2009 Publications

  • Bastiani M, Liu L, Hill MH, Jedrychowski MP, Nixon SJ, Lo HP, Abankwa D, Luetterforst R, Fernandez-Rojo, Breen MR, Steven P, Gygi SP, Vinten J, Walser PJ, North KN, Hancock JF, Pilch PF and Parton RG (2009). MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. J Cell Biol, 185, 1259-1273.
  • Bhattacharya R, Cabral F (2009). Molecular basis for class V β-tubulin effects on microtubule assembly and paclitaxel resistance. J Biol Chem, 284, 13023–13032.
  • Bick RJ, Oakes J L, Actor J K, Cleary L J, Felleman D J, Ownby A R, Weisbrodt NW, Seifert W E, Jr (2009). Integrative Teaching: Problem Solving and Integration of Basic Science Concepts into Clinical Scenarios using Team-Based Learning. J Int Assoc of Med Sci Ed, 19,126-134.
  • Botelho RJ, Harrison RE, Stone JC, Hancock JF, Philips MR, Jongstra-Bilen J, Mason D, Plumb J, Gold MR, Grinstein S (2009). Localized diacylglycerol-dependent stimulation of Ras and Rap during phagocytosis. J Biol Chem, 284, 28522-28532.
  • Bryan, N and Murad, F (2009). What is Nitric Oxide, Chapter in Food, Nutrition and Nitric Oxide Pathway, N. Bryan, ed, DESTech Pub.
  • Bryan NS, Bian K, Murad F (2009). Discovery of the nitric oxide signaling pathway and targets for drug development. Front Biosci, 14, 1-18.
  • Burke JE, Babakhani A, Gorfe AA, Kokotos G, Li S, Woods VL Jr, McCammon JA, Dennis EA (2009). Location of inhibitors bound to group IVA phospholipase A2 determined by molecular dynamics and deuterium exchange mass spectrometry. J Am Chem Soc, 131:8083-8091.
  • Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, and Wittwer CT (2009). The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR. Clinical Chemistry, 55, 609-620, PMID19246619.
  • Carr HS, Cai C, Keinanen K, and Frost JA (2009). Interaction of the RhoA exchange factor Net1 with Dlg1 protects it from proteasome mediated degradation and potentiates Net1 activity. J Biol Chem, 284, 24269-24280.
  • Cescato R*, Loesch KA*, Waser B, Mäcke HR, Rivier JE, Reubi JC, Schonbrunn A (2009). Agonist biased signaling at the sst2A receptor: The pan-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways. Mol Endocrinology, [Epub ahead of print].
  • Dessauer CW (2009). Adenylyl Cyclase-AKAP Complexes: The Next Dimension in cAMP Signaling. Mol Pharm, 76:935-941.
  • Dial EJ, Tran DM, Romero JJ, Zayat M, Lichtenberger LM (2009). A direct role of secretory phospholipase A2 and lysophosphatidylcholine in the mediation of lipopolysaccharide-induce gastric injury. Shock, [Nov 20 Epub ahead of print].
  • Du G and Frohman MA (2009). A lipid-signaled myosin phosphatase surge disperses cortical contractile force early in cell spreading. Mol Biol Cell, 20, 200-8.
  • Edreira MM, Li S, Hochbaum D, Wong S, Gorfe AA, Ribeiro-Neto F, Woods VL Jr, Altschuler DL (2009). Phosphorylation-induced conformational changes in Rap1b: allosteric effects on switch domains and effector loop. J Biol Chem, 284, 27480-274806.
  • Esechie A and Du G (2009). Increased lipogenesis in cancer. Commun Integr Biol. 2, 86-90.
  • Garg, S, Boerma M, Wang J, Fu Q, Loose DS, Kumar S, Hauer-Jensen M (2009). Influence of sublethal total body irradiation on immune cell populations in the intestinal mucosa. Radiation Research, in press.
  • Gilcrease MZ, Kilpatrick SK, Woodward WA, Zhou X, Nicolas MM, Corley LJ, Fuller GN, Tucker, SL, Diaz LK, Buchholz TA, and Frost JA (2009). Co-Expression of Beta4 Integrin and Guanine Nucleotide Exchange Factor Net1 Identifies an Aggressive Subgroup of HER2-Positive Breast Cancer. Cancer Epidemiology, Biomarkers and Prevention, 18, 80-86.
  • Gorfe AA, Lu B, Yu Z, McCammon JA (2009). Enzymatic activity versus structural dynamics: the case of acetylcholinesterase tetramer. Biophys J, 97, 897-905.
  • Grant BJ, Gorfe AA, McCammon JA (2009). Large conformational changes in proteins: signaling and other functions. Curr Opin Struct Biol, 20, 1–6.
  • Gorfe AA (2009). Mechanisms of Allostery and Membrane Attachment in Ras GTPases: Implications for Anti-cancer Drug Discovery. Current Medical Chem, 2009 Nov 24.
  • Herrera JJ, Haywood-Watson II RJ, Grill RJ (2009). Acute and chronic deficits in the urinary bladder following spinal contusion injury in the adult rat. J Neurotrauma, (epub) Nov 5.
  • Inaba H, Hokamura K, Nakano K, Nomura R, Katayama K, Nakajima A, Yoshioka H, Taniguchi K, Kamisaki Y, Ooshima T, Umemura K, Murad F, Wade K, Amana K (2009). Upregulation of S100 calcium-binding protein A9 is required for induction of smooth muscle cell proliferation by a periodontal pathogen. FEBS Lett. 583, 128-34.
  • Inder K, Lau C, Loo D, Chaudhary N,Goodall A, Martin S, Jones A, Parton RG, Hill M and Hancock JF (2009). Nucleophosmin and nucleolin regulate K-Ras plasma membrane interactions and MAPK signal transduction. J Biol Chem, 284, 28410-28419.
  • Ingelmo-Torres M, González-Moreno E, Kassan A, Hanzal-Bayer M, Tebar F, Herms A, Grewal T, Hancock JF, Enrich C, Bosch M, Gross S, Parton RG and Pol A (2009). Hydrophobic and basic domains target proteins to lipid droplets. Traffic, 10, 1785-1801.
  • Izzat NN, Overturf M, Weisbrodt NW, Loose DS (2009). Bile acid transport in hypercholesterolemic resistant rabbits. J Physiol Pharmacol, 60,79-84.
  • Kapiloff MA, Piggott LA, Sadana R, Li J, Heredia LA, Henson E, Efendiev R, and Dessauer, CW (2009). An adenylyl cyclase-mAKAPβ signaling complex maintains basal cAMP levels in cardiac myocytes. J Biol Chem, 284, 23540-23546.
  • Khavrutskii IV, Gorfe AA, Lu B, McCammon JA (2009). Free energy for the permeation of Na(+) and Cl(-) ions and their ion-pair through a zwitterionic dimyristoyl phosphatidylcholine lipid bilayer by umbrella integration with harmonic fourier beads. J Am Chem Soc, 131, 1706-1716.
  • Kiskowski MA, Hancock JF, Kenworthy AK (2009). On the use of Ripley’s K-function and its derivatives to analyze domain size. Biophys J, 97,1095-103.
  • Kunjilwar KK, Fishman HM, Englot DJ, O’Neil RG, Walters ET (2009). Long-lasting hyperexcitability induced by depolarization in the absence of detectable Ca2+ signals. J Neurophysiol, 101,1351–1360.
  • Lee DF, Kuo HP, Liu M, Chou CK, Xia W, Du Y, Shen J, Huo L, Chen CT, Hsu MC, Li CW, Ding Q, Liao TL, Lai CC, Lin AC, Chang YH, Tsai SF, Li LY, Hung MC. KEAP1 E3 ligase-mediated down regulation of NF-KappaB signaling by targeting IKKbeta. Mol Cell., 2009 Oct 9;36(1):131-40. * Cover paper of 2009 October 9th Issue of Molecular Cell.
  • Lichtenberger LM, Romero JJ, Dial EJ (2009). Evaluation of the GI safety and therapeutic efficacy of parenterally administered phosphatidylcholine-associated indomethacin in rodent model systems. Brit J Pharmacol, 157, 252-7.
  • Lichtenberger LM, Romero, JJ, Dial EJ, Moore JE (2009). Naproxen-PC: a GI safe and highly effective anti-inflammatory. Inflammopharmacology 16: 1-5.
  • Liu Q, Bee MS, Schonbrunn A (2009). Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation. Mol Pharmacol, 76, 68-80.
  • Mor A, Wynne J, Ahearn IM, Dustin M, Du G, Philips MR (2009). Phospholipase D1 Regulates Lymphocyte Adhesion via Upregulation of Rap1 at the Plasma Membrane. Mol Cell Biol, 29, 3297-306.
  • Murad F, Barber R (2009). A hypothesis about cellular signaling with nitric oxide in the earliest life forms in evolution. Free Radical Biol. Med, doe:10.1016/j.freeradbiomed.2009.05.005.
  • Nabilsi NH, Broaddus R, and Loose DS (2009). DNA methylation inhibits p53 mediated survivin repression. Oncogene, 28, 2046-50.
  • Pichot CS, Hartig M, Xia L, Lee FY, Frost JA, and Corey SJ (2009). Dasatinib Synergizes with Doxorubicin to Block Growth, Migration, and Invasion of Breast Cancer Cells. British Journal of Cancer, 101, 38-47.
  • Prior IA, Hancock JF, Henis Y (2009). Ras acylation, compartmentalization and signaling nanoclusters. Mol Membr Biol, 26, 80-92.
  • Puji A, Pike T, Widberg C, Payne E, Harding A, Hancock JF, Gabrielli B (2009). MAPK pathway activation delays G2/M progression by destabilizing CDC25B. J Biol Chem, 284, 33781-33788.
  • Quock R, Chan JT (2009). Fluoride content of bottled water and its implications for the general dentist. General Dentistry, 57, 29-33.
  • Quock R, Chan JT (2009). Water fluoride concentrations in and around the greater Houston metropolitan area. Texas Dental Journal, 126,146-149.
  • Reisenauer MR, Anderson M, Huang L, Zhang Z, Zhou Q, Kone BC, Morris AP, Lesage GD, Dryer SE, Zhang W (2009). AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha. J Biol Chem, 284, 35659-69.
  • Ross JA, Hanyin Cheng H, Nagy ZS, Frost JA and Kirken RA (2009). Protein Phosphatase 2A (PP2A) regulates Interleukin-2 Receptor complex formation and JAK3/STAT5 activation. J Biol Chem, in press.
  • Rubinstein M, Peleg S, Berlin S, Brass D, Keren-Raifman T, Dessauer CW, Ivanina T, and Dascal N (2009). Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by Gαi and Gβγ. J. Physiol, 587, 3473-3491.
  • Sadana R and Dessauer CW (2009). Physiological Roles for G-Protein Regulated Adenylyl Cyclase Isoforms: Insights from Knockout and Overexpression Studies. NeuroSignals, 17, 5-22.
  • Sadana R, Dascal N, and Dessauer CW (2009). N-terminus of Type 5 Adenylyl Cyclase Scaffolds Gs Heterotrimer. Mol Pharm, 76, 1256-1264.
  • Su W, Yeku O, Olepu S, Genna A, Park JS, Ren H, Du G, Gelb M, Morris A, Frohman MA (2009). FIPI, a Phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. Mol Pharmacol, 75, 437-46.
  • Toy EC, Weisbrodt N, Dubinsky WP, O’Neil RG, Walters ET, Harms KP (2009). Case Files: Physiology, 2nd edition. Lange Medical Books/McGraw-Hill, New York.
  • Walters ET (2009). Chronic pain, memory, and injury: Evolutionary clues from snail and rat nociceptors. Int J Comp Psychol, 22,127–140.
  • Walters ET, Moroz, LL (2009). Molluscan memory of injury: Evolutionary insights into chronic pain and neurological disorders. Brain Behav Evol, 74,206-218.
  • Westin SN, Broaddus RR, Deng L, McCampbell A, Lu KH, Lacour RA, Milam MR, Urbauer DL., Mueller P, Pickar JH, Loose DS (2009). Molecular clustering of endometrial carcinoma based on estrogen-induced gene expression. Cancer Biol Ther, 8, 2126-2135.
  • Wu J, Bonsra AN, Du G (2009). pSM155 and pSM30 vectors for miRNA and shRNA expression. Methods Mol Biol, 487, 205-219.
  • Xie R, Schlumbrecht M, Shipley GL, Xie SS, Bassett RL, Broaddus RR (2009). S100A4 mediates endometrial cancer invasion and is a target of TGF-β1 signaling. Lab Invest, 89, 937-947.
  • Yakubovich D, Rishal I, Dessauer CW, and Dascal N (2009). Amplitude histogram-based method of analysis of patch clamp recordings that involve extreme changes in channel activity levels. J. Mol. Neuroscience, 37, 201-211.
  • Yang H, Cabral F, Bhattacharya R (2009). Tubulin isotype specificity and identification of the epitope for antibody Tub 2.1. Protein Engineering, Design and Selection 22, 625–629.
  • Zhang Q, Shen Q, Celestino J, Milam MR, Westin S, Lacour R, Meyer L, Shipley GL, Davies PJ, Deng L, McCampbell AS, Broaddus RR, Lu KH (2009). Enhanced estrogen-induced proliferation in obese rat endometrium. Am J of Obstet and Gynecol, 200, 186.e1-8.
  • Zhang Y and Du G (2009). Phosphatidic acid regulation of Ras small GTPases. Biochim Biophys Acta, 1791,850-5.
  • Zhou, C., Wu, J., Borillo, J., Torres, L., McMahon, J., Lou, Y-H. Potential Roles of a Special CD8αα+ Cell Population and CC Chemokine Thymus-Expressed Chemokine in Ovulation Related Inflammation. The Journal of Immunology, 2009, 182:596-603.
  • Zhou Y, Doyen R, Lichtenberger LM (2009). The role of membrane cholesterol in determining bile acid cytotoxicity and cytoprotection of ursodeoxycholic acid. Biochim Biophys Acta, 1788, 507-527.