Recently, in a university-wide e-newsletter, Dean Barbara Stoll highlighted the work of Cardiovascular Medicine’s own Dr. Heinrich Taegtmeyer for his work examining cardiac metabolism and the various methods employed in its study. Her comments, shown below as an excerpt from her newsletter, reflect a growing pride in the members of McGovern Medical School with whom she has met and interacted on various occasions. Please take a moment to look through Dr. Taegtmeyer’s article in Circulation Research by clicking on the link in the excerpt below.
Dr. Heinrich Taegtmeyer, professor of medicine, is the lead author on a recently published American Heart Association (AHA) Statement on “Assessing Cardiac Metabolism.” The work was commissioned, reviewed, and approved by the AHA’s Council on Basic Cardiovascular Sciences to provide a collective and curated resource on methods and models used to investigate cardiac metabolism, ranging from gene expression of metabolic genes to enzyme activities and metabolic flux analyses. A second important aim of the statement is to serve as a standard for rigor and reproducibility in scientific research. I asked Dr. Taegtmeyer to comment on this remarkable work. His thoughts, “How does the heart make just enough ATP to sustain its pump action, one beat at a time? As an engine, that heart turns chemical energy into mechanical energy, and it does this in a highly regulated and intricate way. As all medical students know, the intermediary metabolism of energy providing substrates (glucose and fat) is probably the best understood of any major biochemical networks. Yet understanding and correcting disturbances in the flux of energy remains a major unmet medical need, for example in the treatment of patients with heart failure. The same can be said about cancer, diabetes, or epilepsy.” Read the full article in Circulation Research.