Biography

Dr. Liang Zhu received her Ph.D. degree in Statistics in 2008 from University of Missouri – Columbia. After her graduation, she worked in the Department of Biostatistics at St. Jude Children’s Research Hospital. In 2016, she joined the University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School as an Associate Professor. Dr. Zhu’s current research focuses on longitudinal data analysis, survival analysis, semiparametric methods, as well as applications in epidemiology and clinical trials.

Education

Doctoral Degree
Statistics, University of Missouri – Columbia
Bachelor Degree
Engineering Management, Tongji University, Shanghai, China

Areas of Interests

Research Interests

  • Longitudinal data analysis
  • Survival analysis
  • Clinical trials
  • Epidemiology

Publications

Publication Information

Statistical Methods Research

Zhu, L., Tong, X. and Sun, J.: A transformation approach for the analysis of interval- censored failure time data. Lifetime Data Analysis 14, 115-230, 2008.

Zhu, L., Sun, J. and Wood, P.: Statistical methods for the analysis of alcohol and drug use for young adults. Journal of Data Science 7, 469-485, 2009.

Sun, L., Zhu, L. and Sun, J.: Regression analysis of multivariate recurrent event data with time-varying covariate effects. Journal of Multivariate Data Analysis 100, 2214-2223, 2009.

Tong, X., Zhu, L., and Sun, J.: Variable selection of recurrent event data by nonconcave penalized estimating equation. Lifetime Data Analysis 16(4): 478-90, 2010.

Zhu, L., Sun, J., Tong, X. and Srivastava, D.K.: Regression analysis of multivariate recurrent event data with a dependent terminal event. Lifetime Data Analysis 16(4): 478-90, 2010.

Zhu, L., Sun, J., Tong, X. and Pounds, S.: Regression Analysis of Longitudinal Data with Informative Observation Times and Application to Medical Cost Data. Statistics in Medicine 30(12): 1429-1440, 2011.

Zhu, L., Sun, J., Srivastava, D.K., Tong, X., Leisenring W., Zhang, H., and Robison, L.L.: Semi-parametric Transformation Models for Joint Analysis of Multivariate Recurrent and Terminal Events. Statistics in Medicine 30(25): 3010-3023, 2011

Zhang, H., Lu, N., Feng, C., Thurston, S.W., Xia, Y., Zhu, L. and Tu, X.M.: On Fitting Generalized Linear Mixed-effects Models for Binary Responses using Different Statistical Packages. Statistics in Medicine 30(20): 2562-2572, 2011.

Zhu, L., Zhao, H., Sun, J., Pounds, S. and Zhang, H.: Joint Analysis of Longitudinal Data and Recurrent Episodes Data with Application to Medical Cost Analysis. Biometrical Journal 55(1):5-16, 2013.

Zhu, L., Zhao, H., Tong, X., Sun, J., Srivastava, D.K., Leisenring W. and Robison, L.L.: Statistical analysis of mixed recurrent event data with application to cancer survivor study. Statistics in Medicine 32 (11): 2013.

Chen, M., Tong, X., and Zhu, L.: A linear transformation model for multivariate interval-censored failure time data. Canadian Journal of Statistics 41(2): 275-290, 2013.

Tong, X., Zhu, L., Leng, C., Leisenring, W., and Robison, L.L.: A General Semiparametric Hazards Regression Model: Efficient Estimation and Structure Selection. Statistics in Medicine 32(28): 4980-4994, 2013.

Zhu, L., Tong, X., Sun, J., Leisenring, W., and Robison, L.L.: Regression analysis of mixed recurrent-event and panel-count data. Biostatistics 15(3):555-68; 2014

Zhu, L., Zhao, H., Sun, J., and Stanley, P.A.: Conditional Approach for Regression Analysis of Longitudinal Data with Informative Observation Time and Non-negligible Observation Duration. Communications in Statistics, Theory and Methods 43(23), 4998-5011, 2014

Zhu, L., Zhao, H., Sun, J., Leisenring W. and Robison, L.L.: Regression analysis of mixed recurrent-event and panel-count data with additive rate models. Biometrics 71(1):71-79; DOI: 10.1111/biom.12247, 2015.

Jin, J., Zhu, L., Tong, X. and Ness, K.K.: T-type Corrected-Loss Estimation for Error-in-Variable Model. Communications in Statistics, Theory and Methods 2015 (Accepted).

Zhang, H., He, H., Lu, N., Zhu, L., Zhang, B., Zhang, Z. and Tang, L.: A Non-parametric Model to Address Overdispersed Count Response in a Longitudinal Data Setting with Missingness. Statistical Methods in Medical Research 0(0) 1–15, 2015.

Yu, G., Zhu, L., Li, Y., Sun, J., Robison, L.L: Regression Analysis of Mixed Panel Count Data with Dependent Terminal Events. Statistics in Medicine, 36 (10): 1669-1680, 2017

Yu, G., Zhu, L., Sun, J., Robison, L.L: Regression analysis of incomplete data from event history studies with the proportional rates model. Statistics and its Interface, 2017 (In press).

Collaborative Research

Srinivasan A., Seifried S., Zhu, L., Bitar W., Srivastava D.K., Shenep J.L., Bankowski M.J., Flynn P.M. and Hayden R.T.: Methicillin-resistant staphylococcus aureus infections in children and young adults infected with HIV. AIDS Research and Human Retroviruses 25 (12):1219-1224, 2009.

Srinivasan A., Seifried S., Zhu, L., Srivastava D.K., Flynn P.M., Shenep J.L., Bankowski M.J., and Hayden R.T.: Panton-Valentine Leukocidin positive methicillin-resistant Staphylococcus aureus infections in children with cancer. Pediatric Blood and Cancer 53(7):1216-20, 2009.

Srinivasan A., Seifried S., Zhu, L., Srivastava D.K., Flynn P.M., Bankowski M.J., Shenep J.L., and Hayden R.T.: Staphylococcus aureus bacteremia in pediatric patients with cancer. Pediatric Infectious Disease Journal 29(2):172-4, 2010.

Srinivasan A., Seifried S., Zhu, L., Srivastava D.K., Perkins R., Shenep J.L., Bankowski M.J., and Hayden R.T.: Increasing prevalence of nasal and rectal colonization with Methcillin-resistant Staphylococcusaureus in children with cancer. Pediatric Blood and Cancer 55(7):1317-22, 2010.

Krull K.R., Khan R.B., Ness K.K., Ledet D., Zhu, L., Pui C.H., Howard S.C., Srivastava D.K., Sabin N. D., Hudson M.M., and Morris E.B.: Symptoms of Attention-Deficit/Hyperactivity Disorder in Long-Term Survivors of Childhood Leukemia. Pediatric Blood and Cancer 57(7):1191-1196, 2011.

Batson A.K., Lottick N.K., Zhu, L., Bordes V., Srivastava D.K., Zeltzer L.K., Robison L.L., and Krull K.R.: Predictors of independent living status in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. Pediatric Blood and Cancer DOI: 10.1002/pbc.22982 2011.

Cox, C. L., Zhu, L., Hudson, M. M., Steen, B. D., Robison, L. L., and Oeffinger, K. C.. Survivors Intrapersonal Profiles Predict Participation in Medical Surveillance: The Childhood Cancer Survivor Study. Psycho-Oncology 21(5): 469-478, 2011.

Green, D.M, Cox, C.L., Zhu, L., Stovall, M., Nolan, V.G., Ness, K.K., Donaldson, S. S., Oeffinger, K.C., Meacham, L.R., Sklar, C.A., Krull, K.R., Armstrong, G.T., and Robison, L.L.: Antidepressant use and obesity in adult survivors of childhood cancer. A report from the childhood cancer survivor study. Journal of Clinical Oncology 30(3):246-55, 2012.

Cox, C.L., Zhu, L., Finnegan, L., Hudson, M.M., Robison, L.L., and Oeffinger, K.C.: Profiling adult childhood cancer survivors: informing tailored care to modify late effects. Psycho-Oncology 21(5):469-78, 2012.

Krull, K.R., Sabin, N.D., Reddick, W.E., Zhu, L., Armstrong, G.T., Green, D.M., Arevalo, A.R., Krasin, M.J., Srivastava, D.K., Robison, L.L. and Hudson, M.M.: Neurocognitive Function and Central Nervous System Integrity in Adult Survivors of Childhood Hodgkin Lymphoma. Journal of Clinical Oncology 30(29):3618-24, 2012.

Motosue M.M., Zhu L., Srivastava D.K., Stokes D.C., Hudson M.M., McPherson V., Srinivasan S., Krasin M.J., Green D.M., Spunt S.K., and Inaba H.: Pulmonary function after whole lung irradiation in pediatric patients with solid malignancies. Cancer 118(5): 1450-1456, 2012.

Armstrong, G.T., Joshi, V.M., Zhu, L., Srivastava, D., Zhang, N., Ness, K.K., Stokes, D.C., Krasin, M.T., Fowler, J.A., Robison, L.L., Hudson, M.M., and Green, D.M.: Increased Tricuspid Regurgitant Jet Velocity by Doppler Echocardiography in Adult Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study. Journal of Clinical Oncology 1(6):774-781, 2013.

Brinkman T.M., Zhu, L., Zeltzer L.K., Recklitis C.J., Kimberg C., Muriel A.C., Stovall M., Srivastava D.K., Robison L.L., and Krull K.R.: Longitudinal patterns of psychological distress in adult survivors of childhood cancer. British Journal of Cancer 109, 1373-1381, 2013.

Green D.M., Zhu L., Zhang N., Sklar C.A., Ke R.W., Kutteh W.H., Klosky J.L., Spunt S.S., Metzger M.L., Navid F., Srivastava D.K., Robison L.L., and Hudson M.M.: The utility of plasma concentrations of inhibin B and follicle stimulating hormone for identification of azoospermic survivors of childhood cancer. A report from the St. Jude Lifetime Cohort Study. Journal of Clinical Oncology 31: 1324-1328, 2013.

Denbo, J., Zhu, L., Srivastava, D.K., Stokes, D., Srinivasan, S., Hudson, M.M., Ness, K.K., Robison, L.L., Neel, M., Rao, B., Navid, F., Davidoff, A.M., and Green, D.M.: Long-term Pulmonary Function after Metastasectomy for Childhood Osteosarcoma: A Report from the St. Jude Lifetime Cohort Study. Journal of the American College of Surgeons 219(2):265-71, 2014.

Khan, R., Hudson, M.M., Ledet, D.S., Morris, E.B., Pui, C.H., Howard, S.C., Krull, K. R., Hinds, P.S., Crom, D., Brown, E., Zhu, L., Rai, S., Kumar, S., and Ness, K.K.: Neurologic morbidity and related quality of life in long-term survivors of childhood acute lymphoblastic leukemia. Journal of Cancer Survivorship 8(4):688-96, 2014.

Sadighi, Z.S., Ness, K.K., Hudson, M.M., Morris, B.E., Ledet, D.V., Pui, C.H., Howard, S.C., Krull, K.R., Browne, E., Crom, D., Hinds, P.S., Zhu, L., Srivastava, D. K., and Khan, R.B.: Headache types, related morbidity, and quality of life in survivors of childhood acute lymphoblastic leukemia: a prospective cross sectional study. European Journal of Pediatric Neurology 18(6):722-9, 2014.

Ness, K.K., Kaste, S.C., Zhu, L., Pui, C.H., Jeha, S., Nathan, P.C., Inaba, H., Wasilewski, K., Shah, D., Wells, R.J., Karlage, R.E., Robison, L.L., and Cox, C.L.: Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia Leuk Lymphoma 56(4):1004-11, 2015.

Khan, R.B., Hudson, M.M., Ness, K.K., Zhu, L., Srivastava, D.K., and Krull, K. R.: Association of attention deficit disorder with bedside anti-saccades in survivors of childhood leukemia. Journal of Child Neurology DOI: 10.1177/0883073815583689, 31(2):131-3, 2016.

Brimeyer, C., Adams, L, Zhu, L., Srivastava, D.K., Wise, M., Hudson, M.M., and Crabtree, V.M.: Sleep complaints in survivors of pediatric brain tumors. Supportive Care in Cancer 24 (1): 23-31, 2016.

Cox C.L., Zhu L., Ojha R.P., Steen B.D., Ogg S., Robison L.L., Hudson M.M.: Factors supporting cardiomyopathy screening among at-risk adult survivors of pediatric malignancies. Support Care Cancer 25(4):1307-16, 2017.

Sutton J.C., Fay R.M., Huynh C.P., Johnson C.D., Zhu L., Quock R.L.: Dental Faculty Accuracy When Using Diagnostic Codes: A Pilot Study. Journal of Dental Education 81(5): 554-560, 2017. doi: 10.21815/JDE.016.018

Savarraj P., Parsha K.N., Hergenroeder G., Zhu L., Bajgur S., Ahn S., Lee K., Chang T., Kim D., Liu Y., Choi H.: Systematic Model of Peripheral Inflammation after Subarachnoid Hemorrhage. Neurology. 88(16):1535-1545, 2017.

Cox C.L., Zhu L., Ojha R.P., Steen B.D., Ogg S., Robison L.L., Hudson M.M.: Factors Supporting Cardiomyopathy Screening Among At-risk Adult Survivors of Pediatric Malignancies. Supportive Care in Cancer 25(4), 1307–1316, 2017.

Karri J., Cardenas J., Matijevic N., Choi S., Zhu L., Cotton B., Kitagawa R., Holcomb J., Wade C.: The role of fibrinolysis in causing progressive hemorrhagic injury. Shock. (In press), 2017.

Lee C.T., Huang Y.W., Zhu L., Weltman R.: Prevalences of Peri-implantitis and Peri-Implant Mucositis: Systematic Review and Meta-Analysis. Journal of Dentistry. (In press), 2017.