Biography

Dr. Marrelli received a BA in Chemistry from the University of Houston and then a PhD in Cardiovascular Sciences from Baylor College of Medicine. His lab is funded through the NIH and AHA to study multiple aspects of cerebral blood flow in normal and post-stroke conditions.

Education

Doctorate Degree
Baylor College of Medicine - Houston, TX

Areas of Interest

Research Interests

Regulation of cerebral blood flow in healthy conditions and in disease states (e.g. following ischemic stroke, in conditions of amyloidosis, etc.).; Role of endothelial Piezo1 mechanosensitive ion channel in cerebral blood flow regulation; Brain vascular remodeling in aging and pathology; Novel methods of promoting therapeutic hypothermia following stroke.

Publications

  1. Cao, Z. et al. TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke. Sci Rep 7, 17685 (2017).
  2. Fasipe, T.A. et al. Extracellular Vimentin/VWF (von Willebrand Factor) Interaction Contributes to VWF String Formation and Stroke Pathology. Stroke 49, 2536-2540 (2018).
  3. Hong, S.H. et al. Development of barium-based low viscosity contrast agents for micro CT vascular casting: Application to 3D visualization of the adult mouse cerebrovasculature. J Neurosci Res 98, 312-324 (2020).
  4. Kim, G.S. et al. Determining the effect of aging, recovery time, and post-stroke memantine treatment on delayed thalamic gliosis after cortical infarct. Sci Rep 11, 12613 (2021).
  5. Kim, G.S. et al. Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke. Res Sq (2023).