Assistant Professor, Vivian L. Smith Department of Neurosurgery
Education & Training
- Graduate School
- University of Cincinnati (Medical Genetics)
Clinical & Research Interests
My clinical interests involve evaluating and educating patients with a personal or family history of hereditary neurological, brain or spine conditions. As the field of medicine evolves, we continue to discover the importance of considering an individual’s family medical history when assessing their risk for developing various health conditions in the future. Genetic risk factors have been shown to impact the development of several adult neurological conditions, such as brain aneurysms, hereditary cancer syndromes associated with brain tumors, neurofibromatosis, epilepsy, neuromuscular dystrophies and hereditary movement disorders. Education and counseling regarding potential genetic risk factors allows the individual to make informed choices regarding issues such as genetic testing, disease screening options, and reproductive decisions. During a typical genetic counseling appointment, we will discuss a variety of topics related to genetics and disease, including personal and family medical history, genetic risk and inheritance patterns, and the impact of disease on the family.
My research interests include working with the Neurosciences Research Repository with the goal of understanding the genetic basis of hereditary neurological disease. Specifically, I am working with Dr. Teresa Santiago-Sim in her efforts discover new genetic variants implicated in familial intracranial aneurysms.
- Nguyen, J., Qualmann, K., Okashah, R., Reilly, A., Alexeyev, M., & Campbell, D. (In press). 5p Deletions: Current Knowledge and Future Directions. American Journal of Medical Genetics Part C: Seminars in Medical Genetics.
- Lutgen, V., Resch, J., Qualmann, K., Raddatz, N.J., Panhans, C., Olander, E.M., Kong, L., Choi, S., Mantsch, J.R., & Baker, D.A. (2014). Behavioral assessment of acute inhibition of system xc– in rats. Psychopharmacology, 1-11.
- Lutgen, V., Qualmann, K., Resch, J., Kong, L., Choi, S., & Baker, D. A. (2013). Reduction in phencyclidine induced sensorimotor gating deficits in the rat following increased system xc– activity in the medial prefrontal cortex. Psychopharmacology. 226(3), 531-540.
- Qualmann, K., Greiner, H.M., Myers, M.F. Horn, P.S. & Spaeth, C.G. (2014, Fall). “Family history of epilepsy and central nervous system comorbidities as a prognostic indicator for resective surgery outcomes among pediatric epilepsy patients.” Platform presentation to be given at Concurrent Papers session at the National Society of Genetic Counselors Annual Education Conference, New Orleans, LA.
- Lutgen, V., Madayag, A., Dietrich, P., Qualmann, K., Baker, D.A. (2011, Fall). “Cognitive deficits produced by impaired glutamate release from astrocytes: potential implications of diminished system xc– activity for schizophrenia and addiction.” Poster session presented at American College of Neuropsychopharmacology, Waikoloa, HI.
- Lutgen, V., Choi, S., Madayag, A., Qualmann, K., Dietrich, P., Bolsvert, J., Baker, D.A. (2011, Fall). “Contribution of system xc– to cognitive deficits associated with schizophrenia.” Poster session presented at Society for Neuroscience, Washington, D.C.
- Lutgen, V., Madayag, A., Dietrich, P., Qualmann, K., Baker, D.A. (2010, Fall). “System xc– as a novel target in the etiology and treatment of schizophrenia.” Poster session presented at American College of Neuropsychopharmacology, Hollywood, FL.
- Lutgen, V., Madayag, A., Qualmann, K., Dietrich, P., Baker, D.A. (2010, Fall). “Cystine-glutamate exchange in the prefrontal cortex of gestational methylazoxymethanol treatment.” Poster session presented at Society for Neuroscience, San Diego, CA.