The focus Dr. Huard’s lab is to understand basic stem cell biology and translate that knowledge to the clinic to aid in healing and regeneration of a variety of tissues. He is concentration on gene therapy, tissue engineering and regenerative medicine applications based on the use of muscle-derived stem cells (MDSCs). The MDSCs that have been isolated by Dr. Huard’s lab are currently undergoing clinical trials for the treatment of urinary stress incontinence and myocardial infarction. As of this date, more than 400 patients in Canada and the US have volunteered for this stem cell therapy.
Major Research Interests:
- Skeletal muscle stem cell isolation and their characterization
- Alleviation of the muscular degeneration associated with Duchenne’s muscular dystrophy (DMD) through MDSC transplantation
- Bone, articular cartilage, ligament, meniscus regeneration and repair through stem cell transplantation
- Cardiac and skeletal muscle injury repair, regeneration, and fibrosis prevention
- Peripheral nerve regeneration using MDSCs
- The use of MDSCs as a source for paracrine factors to alleviate the phenotypic changes association with natural aging and progeria