Scleroderma Publications

  1. Saketkoo LA, Mittoo S, Huscher D, Khanna D, Dellaripa PF, Distler O, Flaherty KR, Frankel S, Oddis CV, Denton CP, Fischer A, Kowal-Bielecka OM, LeSage D, Merkel PA, Phillips K, Pittrow D, Swigris J, Antoniou K, Baughman RP, Castelino FV, Christmann RB, Christopher-Stine L, Collard HR, Cottin V, Dannoff S, Highland KB, Hummers L, Shah AA, Kim DS, Lynch DA, Miller FW, Proudman SM, Richeldi L, Ryu JH, Sandorfi N, Sarver C, Wells AU, Strand V, Matteson EL, Brown KK, Seibold JR. Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials. Thorax. 2014 Jan 28. 10.1136/thoraxjnl-2013-204202. [Epub ahead of print] PubMed
  2. Wang J, Guo X, Yi L, Guo G, Tu W, Wu W, Yang L, Xiao R, Li Y, Chu H, He D, Jin L, Mayes MD, Zou H, Zhou X. Association of HLA-DPB1 with scleroderma and its clinical features in Chinese population. PLoS One. 2014 Jan 31:9(1):e87363 PubMed
  3. Baron M, Chung L, Gyger G, Hummers L, Khanna D, Mayes MD, Pope JE, Shah AA, Steen VD, Steele R, Tatibouet S, Herrick A, Muller-Ladner U, Hudson M. Consensus opinion of a North American working group regarding the classification of digital ulcers in systemic sclerosis. Clin Rheum. 2014 Feb; 13(2):207-14 PubMed
  4. Mayes MD, Bossini-Castillo L, Gorlova O, Martin JE, Zhou X, Chen WV, Assassi S, Ying J, Tan K, Arnett FC, Reveille JD, Guerra S, Teruel M, Carmona FD, Gregersen PK, Lee AT, López-Isac E, Ochoa E, Carreira P, Simeón CP, Castellvi I, González-Gay MA, the Spanish Scleroderma Group, Koeleman BP, Zhernakova A, Padyukov L, Alarcón-Requelme M, Wijmengz C, Brown M, Beretta L, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JHW, Voskuyl AE, Scherwegh AJ, Hesselstrand R, Nordin A, Airó P, Lunardi C, Shiels P, van Laar PM, Herrick A, Worthington J, Denton C, Wigley FM, Hummers LK, Varga J, Hinchcliff ME, Baron M, Hudson M, Pope JE, Furst ED, Khanna D, Phillips K, Schiopu E, Segal BM, Molitor JA, Silver RM, Steen FD, Simms RW, Lafyatis RA, Fessler BJ, Frech TM, AlKassab F, Docherty P, Kaminska E. Khalidi N, Jones HN, Markland J, Robinson D, Broen J, Radstake TRDJ, Fonseca C, Martin J. Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. Am J Hum Genet. 2014 Jan 2;94(1):47-61. Doi: 10.1016/j.alhg.2013.12.002 PubMed
  5. Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK. Identification of cadherin-11 as a mediator of dermal fibrosis and possible role in systemic sclerosis. Arthritis Rheum. 2013 Nov 18. doi: 10.1002/art.38275. [Epub ahead of print] PubMed
  6. Draeger HT, Assassi S, Sharif R, Gonzalez EM, Harper B, Arnette FC, Manzoor A, Lange RA, Mayes MD. Right bundle branch block: A predictor of mortality in early systemic sclerosis. PLoS One. 2013 Oct 31;8(10):e78808 PubMed
  7. Dharamsi JW, Victor S, Aguwa N, Ahn C, Arnett F, Mayes MD, Jacobe H. Morphea in adults and children cohort III: Nested case-control study – the clinical significance of autoantibodies in morphea. JAMA Dermatol. 2013 Oct;149(10):1159-65. doi: 10.1001/jamadermatol.2013.4207 PubMed
  8. Van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifani G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JPH, van der Graaf J, den Heijer M, Kallenberg CGM, Bijl M, Loof A, van den Berg WB, Joosten LAP, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PLCM, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TRDJ. Proteome-wide analysis identifies the chemokine CSCL4 as a unique biological marker that drives critical pathological events in systemic sclerosis. New Eng J Med. 2014 Jan 30;370(5):433-43 PubMed
  9. López-Isac E, Bossini-Castillo L, Simeon CP, Egurbide MV, Alegre-Sancho JJ, Callejas JL, Roman-Ivorra JA, Freire M, Beretta L, Santaniello A, Airó P, Lunardi C, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JHW, Schuerwegh AJ, Vonk MC, Voskuyl AE, Shiels PG, van Laar JM, Fonseca C, Denton C, Herrick A, Worthington J, Assassi S, Koeleman BP, Mayes MD, Radstake TRDJ, Martin J. A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility. Arthritis Res Ther. 2014 Jan 9;16(1):R6 PubMed
  10. Merz EL, Malcarne VL, Assassi S, Nair DK, Graham TA, Yellman BP, Estrada y Martin R, Mayes MD. Biopsychosocial typologies of pain in a cohort of patients with systemic sclerosis. Arthritis Care Res (Hoboken). 2013 Sep 19. Doi: 10.1002/acr.22171. [Epub ahead of print] PubMed
  11. van den Hoogen F, Khanna D, Fransen J, Johnson SR, Baron M, Tyndall A, Matucci-Cerinic M, Naden RP, Medsger TA Jr, Carreira PE, Riemekasten G, Clements PJ, Denton CP, Distler O, Allanore Y, Furst DE, Gabrielli A, Mayes MD, van Laar JM, Seibold JR, Czirjak L, Steen VD, Inanc M, Kowal-Bielecka O, Müller-Ladner U, Valentini G, Veale DJ, Vonk MC, Walker UA, Chung L, Collier DH, Ellen Csuka M, Fessler BJ, Guiducci S, Herrick A, Hsu VM, Jimenez S, Kahaleh B, Merkel PA, Sierakowski S, Silver RM, Simms RW, Varga J, Pope JE. 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative. Ann Rheum Dis. 2013 Nov 1;72(11):1747-55. doi: 10.1136/annrheumdis-2013-204424 PubMed
  12. Zhou XD, Yi L, Guo XJ, Chen E, Zou HJ, Jin L, Mayes MD, Assassi S, Wang JC. Association of HLA-DQB1*0501 with scleroderma and its clinical features in Chinese population. Int J Immunopathol Pharmacol. 2013 Jul-Sept;26(3):747-51 PubMed
  13. Liu X, Mayes MD, Tan FK, Wu M, Reveille JD, Harper BE, Draeger HT, Gonzalez B, Assassi S. Correlation of interferon-inducible chemokine plasma levels with disease severity in systemic sclerosis. Arthritis Rheum. 2013 Jan;65(1):226-35 PubMed
  14. Martin JE, Assassi S, Diaz-Gallo LM, Broen JC, Simeón CP, Castellvi I, Vicente-Rabanda E, Fonollosa V, Ortego-Centeno N, González-Gay MA, Espinosa G, Carreira P; Spanish Scloerderma Group; SLEGEN consortium; U.S. Scleroderma GWAS group; BIOLUPUS, Camps M, Sabio JM, D’Alfonso S, Vonk MC, Voskuyl AE, Schuerwegh AJ, Kreuter A, Witte T, Riemakasten G, Hunzelmann N, Airo P, Beretta L, Scorza R, Lunardi C, vanLaar JM, Chee MM, Worthington J, Herrick A, Denton C, Fonseca C, Tan FK, Arnett F, Zhou X, Reveille JD, Gorlova O, Koeleman BP, Radstake TR, Vyse T, Mayes MD, Arlarcón-Requelme ME, Martin J. A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci, Hum Molec Genet 2013 Oct 1:22(19):4021-9 PubMed
  15. Assassi S, Wu M, Tan FK, Chang J, Graham TA, Furst DE, Khanna D, Charles J, Ferguson EC, Feghali-Bostwick C, Mayes, MD. Skin gene expression correlates of severity of interstitial lung disease in systemic sclerosis. Arthritis Rheum 2013 Nov;65(11):2917-27. PubMed
  16. Kwakkenbos L, Jewett LR, Baron M, Bartlett SJ, Furst D, Gottesman K, Khanna D, Malcarne VL, Mayes MD, Mouthon L, Poiraudeau S, Sauve M, Nielson WR, Poole JL, Assassi S, Boutron I, Ells C, van den Ende CHM, Hudson M, Impens A, Körner A, Leite C, Costa Maia A, Mendelson C, Pope J, Steele RJ, Suarez-Almazor ME, Ahmed S, Coronado-Montaya S, Delisle VC, Gholizadeh S, Jang Y, Levis B, Milette K, Mills SD, Razykov I, Sobel RM, Thombs BD. The Scleroderma Patient-centered Intervention Network (SPIN) cohort: Protocol for a cohort multiple randomized controlled trial (mcRCT) design to support trials of psychosocial and rehabilitation interventions in a rare disease context. BMJOpen 2013;3:e003563 PubMed
  17. Yi L, Wang JC, Guo XJ, Gu YH, Tu WZ, Guo G, Yang L, Xiao R, Yu L, Mayes MD, Assassi S, Zou HJ, Zhou XD. STAT4 is a genetic risk factor for systemic sclerosis in Chinese population. Int. J. Immunopathol. Pharmacol. 2013 Apr-Jun:26(6):473-8 PubMed
  18. Carmona FD, Cénit MC, Diaz-Gallo LM, Broen JC, Simeón CP, Carreria PE, Callejas-Rubio JL, Fonollosa V, López-Longo FJ, González-Gay MA, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JH, Madhok R, Shiels P, van Laar JM, Schuerwegh AJ, Vonk MC, Voskuyl AE, Fonseca C, Denton CP, Herrick A, Worthington J, Arnett FC, Tan FK, Assassi S, Radstake TR, Mayes MD, Martin J; Spanish Scleroderma Group. New insight on the Xq28 association with systemic sclerosis. Ann Rheum Dis 2013 Dec 1;72(12):2032-8. PubMed
  19. Liu X, Mayes M, Pedroza CP, Draeger HT, Gonzalez EB, Harper BE, Reveille JD, Assassi S. Does C-reactive protein predict the long-term progression of interstitial lung disease and survival in patients with early systemic sclerosis? Arthritis Care Res. 2013 Aug;65(8):1375-80. Doi: 10.10002/acr.21968. PubMed
  20. Elhaj M, Charles J, Pedroza C, Liu X, Zhou X, Estrada-Y-Martin RM, Gonzalez E, Lewis DE, Draeger HT, Kim S, Arnett FC, Mayes MD, Assassi S. Can serum surfactant protein D or CC-chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis? J Rheumatol. 2013 Jul;40(7):1114-20. PubMed
  21. de Achaval S, Kallen MA, Mayes MD, Lopez-Olivo MA, Suarez-Almazor ME. Use of the patient generated index in systemic sclerosis. J Rheumatol 2013 Aug;40(8):1337-43. PubMed
  22. Wang J, Assassi S, Guo G, Tu W, Wu W, Yang L, Xiao R, Zhao Y, Chu H, Liu J, Ma Y, Kim SJ, Jin L, Mayes MD, Zou H, Zhou X. Clinical and serological features of systemic sclerosis in a Chinese cohort. Clin Rheumatol. 2013 May;32(5):617-21. PubMed
  23. Diaz-Gallo LM, Simeon CP, Broen JC, Orego-Centeno N, Beretta L, Vonk MC, Carreira PE, Vargas S, Román-Ivorra JA, González-Gay MA, Tolosa C, López-Longo FJ, Espinosa G, Vicente EF, Hesslestrand R, Riemekasten G, Witte T, Distler JH, Voskuyl AE, Schuerwegh AJ, Shiels PG, Nordin A, Padyukov L, Hoffmann-Vold AM, Scorza R, Lunardi C, Airó P, van Laar JM, Hunzelmann N, Gathof BS, Kreuter A, Herrick A, Worthington J, Denton CP, Zhou X, Arnett FC, Fonseca C, Koeleman BP, Assassi S, Radstake TR, Mayes MD, Martin J, the Spanish Scleroderma Group. Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility. Ann Rheum Dis. 2013 Jul;72(7):1233-8. PubMed
  24. Walker KM, Pope J, Scleroderma Clinical Trials Consortium (SCTC), Canadian Scleroderma Research Group (CSRG). Treatment of systemic sclerosis complications: what to use when first-line treatment fails – a consensus of systemic sclerosis experts. Semin Arthritis Rheum. 2012 Aug;42(1):42-55 PubMed
  25. Elhaj M, Charles J, Pedroza C, Liu X, Zhou X, Estrada-Y-Martin RM, Gonzalez E, Lewis DE, Draeger HT, Kim S, Arnett FC, Mayes MD, Assassi S. Can serum surfactant protein D or CC-chemokine ligand 18 predict outcome of interstitial lung disease in patients with early systemic sclerosis? J Rheumatol. 2013 Jul;40(7)1114-20. PubMed
  26. Liu X, Mayes M, Pedroza CP, Draeger HT, Gonzalez EB, Harper BE, Reveille JD, Assassi S. C-Reactive protein predicts the long-term progression of interstitial lung disease and survival in patients with early systemic sclerosis. Arthritis Care Res. 2013 Aug;65(8)1375-80. Doi: 10.10002/acr.21968. PubMed
  27. Hung EW, Mayes MD, Sharif R, Assassi S, Machicao VI, Hosing C, St Clair EW, Furst DE, Khanna D, Forman S, Mineishi S, Phillips K, Seibold JR, Bredeson C, Csuka ME, Nash RA, Wener MH, Simms R, Ballen K, Leclercq S, Storek J, Goldmuntz E, Welch B, Keyes-Elstein L, Castina S, Crofford LJ, McSweeney P, Sullivan KM. Gastic antral vascular ectasia and its clinical correlates in patients with early diffuse systemic scleros in the SCOT trial. J. Rheumatol. 2013 Apr 40(4):455-60. PubMed
  28. Mayes MD. The genetics of scleroderma: looking into the postgenomic era. Curr Opin Rheumatol. 2012 Nov;24(6):677-84. Doi:10.1097/BOR.0b013e328358575b. PubMed
  29. Wang J, Assassi S, Guo G, Tu W, Wu W, Yang L, Xiao R, Zhao Y, Chu H, Liu J, Ma Y, Kim SJ, Jin L, Mayes MD, Zou H, Zhou X. Clinical and serological features of systemic sclerosis in a Chinese cohort. Clin Rheumatol. 2013 May;32(5):617-21. PubMed
  30. Diaz-Gallo L-M, Simeon CP, Broen JCA, Orego-Centeno N, Bereta L, Vonk MC, Carreira P, Vargas S, Román-Ivorra JA, González-Gay MA, Tolosa C, López-Longo FJ, Espinosa G, Vicente E, the Spanish Scleroderma Group, Hesslestrand R, Riemekasten G, Witte T, Distler JHW, Voskuyl AE, Schuerwegh AJ, Shiels P, Nordin A, Padyukov L, Hoffmann-Vold A-M, Scorz R, Lunardi C, Airó P, van Laar JM, Hunzelmann N, Gathof B, Kreuter A, Herrick A, Worthington J, Denton C, Zhou X, Arnett FC, Fonseca C, Koeleman BP, Assassi S, Radstake TRDJ, Mayes MD, Martin J. Implication of IL2-IL21 region in systemic sclerosis genetic susceptibility. Ann Rheum Dis. 2013 July;72(7)1233-8. PubMed
  31. Liu X, Mayes MD, Tan FK, Wu M, Reveille JD, Harper BE, Draeger HT, Gonzalez EB, Assassi S. Correlation of interferon-inducible chemokine plasma levels with disease severity in systemic sclerosis. Arthritis Rheum. 2013 Jan;65(1):226-35. doi: 10.1002/art.37742. PubMed
  32. Merz EL, Malcarne VL, Roesch SC, Sharif R, Harper BE, Draeger HT, Gonzalez EB, Nair DK, McNearney TA, Assassi S, Mayes MD. Measuring illness behavior in patients with systemic sclerosis.Arthritis Care Res (Hoboken). 2013 Apr;65(4):585-93. doi: 10.1002/acr.21874. PubMed
  33. Bossini-Castillo L, Martin JE, Broen J, Simeon CP, Beretta L, Gorlova OY, Vonk MC, Ortego-Centeno N, Espinosa G, Carreira P, García de la Peña P, Oreiro N, Román-Ivorra JA, Castillo MJ, González-Gay MA, Sáez-Comet L, Castellví I, Schuerwegh AJ, Voskuyl AE, Hoffmann-Vold AM, Hesselstrand R, Nordin A, Lunardi C, Scorza R, van Laar JM, Shiels PG, Herrick A, Worthington J, Fonseca C, Denton C, Tan FK, Arnett FC, Assassi S, Koeleman BP, Mayes MD, Radstake TR, Martin J., the Spanish Scleroderma Group. Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factor in a large independent replication study. Ann Rheum Dis.2013 Apr;72(4):602-7. PubMed
  34. Sharif R, Mayes MD, Tan FK, Gorlova OY, Hummers LK, Shah AA, Furst DE, Khanna D, Martin J, Bossini-Castillo L, Gonzalez EB, Ying J, Draeger HT, Agarwal SK, Reveille JD, Arnett FC, Wigley FM, Assassi S. IRF5 polymorphism predicts prognosis in patients with systemic sclerosis. Ann Rheum Dis. 2012 Jul;71(7):1197-202. doi: 10.1136/annrheumdis-2011-200901. PubMed
  35. Coustet B, Bouaziz M, Dieudé P, Guedj M, Bossini-Castillo L, Agarwal S, Radstake T, Martin J, Gourh P, Elhai M, Koumakis E, Avouac J, Ruiz B, Mayes M, Arnett F, Hachulla E, Diot E, Cracowski JL, Tiev K, Sibilia J, Mouthon L, Frances C, Amoura Z, Carpentier P, Cosnes A, Meyer O, Kahan A, Boileau C, Chiocchia G, Allanore Y. Independent replication and metaanalysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis. J Rheumatol. 2012 May;39(5):997-1003. PubMed
  36. Martin JE, Broen JC, Carmona FD, Teruel M, Simeon CP, Vonk MC, van t’Slot R, Rodriguez-Rodriguez L, Vicente E, Fonollosa V, Ortego-Centeno N, González-Gay MA, García-Hernández FJ, de la Peña PG, Carreira P, Spanish Scleroderma Group, Voskuyl AE, Schuerwegh AJ, van Reil PL, Kreuter A, Witte T, Riemekasten G, Airo P, Scorza R, Lunardi C, Hunzelmann N, Distler JH, Beretta L, van Laar J, Chee MM, Worthington J, Herrick A, Denton C, Tan FK, Arnett FC, Assassi S, Fonseca C, Mayes MD, Radstake TR, Koeleman BP, Martin J. Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up. Hum. Mol. Genet. 2012 Jun 15;21(12):2825-35. PubMed
  37. Bossini-Castillo L, Martin JE, Broen J, Gorlova O, Simeón CP, Beretta L, Vonk MC, Callejas JL, Castellvi I, Carreira P, García-Hernández FJ, Fernández Castro M, Spanish Scleroderma Group, Coenen MJ, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JH, Koeleman BP, Voskuyl AE, Schuerwegh AJ, Palm Ø, Hesselstrand R, Nordin A, Airó P, Lunardi C, Scorza R, Shiels P, van Laar JM, Herrick A, Worthington J, Denton C, Tan FK, Arnett FC, Agarwal SK, Assassi S, Fonseca C, Mayes MD, Radstake TR, Martin J. A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet. 2012 Feb 15;21(4):926-33. PubMed
  38. Carmona FD, Gutala R, Simeón CP, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E, García-Hernández FJ, García de la Peña P, Fernández-Castro M, Martínez-Estupiñán L, Egurbide MV, Tsao BP, Gourh P, Agarwal SK, Assassi S, Mayes MD, Arnett FC, Tan FK, Martín J; Spanish Scleroderma Group. Novel identification of IRF7 region as an anti-centromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis. 2012; 71:114-9. PubMed
  39. Gorlova O, Martin JE, Rueda B, Koeleman BP, Ying J, Teruel M, Diaz-Gallo LM, Broen JC, Vonk MC, Simeon CP, Alizadeh BZ, Coenen MJ, Voskuyl AE, Schuerwegh AJ, van Riel PL, Vanthuyne M, van't SlotR,Italiaander A, Ophoff RA, Hunzelmann N, Fonollosa V, Ortego-Centeno N, Gonzalez-Gay MA, Garcia-Hernandez FJ, González-Escribano MF, Airo P, van Laar J, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels PG, Westhovens R, Kreuter A, de Baere E, Witte T, Padyukov L, Nordin A, Scorza R, Lunardi C, Lie BA, Hoffmann-Vold AM, Palm O, Garcia de la Peña P, Carreira P, Spanish Scleroderma Group; Rodriguez-Rodriguez L, Vicente E, Fonollosa V, Voskuyl AE, Schuerwegh AJ, van Riel P LCM, Vanthuyne M, Houssiau F, Smith V, de Keyser F, Westhovens R, de Baere E, Kreuter A, Witte T, Riemekasten G, Hesselstrand R, Padyukov L, Nordin A, Lie BA, Hoffmann-Vold A-M, Palm Ø, Airo P, Scorza R, Lunardi C, Hunzelmann N, Beretta L, Tan FK, Arnett FC, Mayes MD, Martin J. Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. PLoS Genet. 2011 Jul;7(7):e1002178. PubMed
  40. Chaudhary P, Chen X, Assassi S, Gorlova O, Draeger H, Harper BE, Gonzalez E, McNearney T, Perry M, Arnett FC, Mayes MD. Cigarette smoking is not a risk factor for systemic sclerosis. Arthritis Rheum. 2011 Oct;63(10):3098-102. doi: 10.1002/art.30492. PubMed
  41. Assassi S, Leyva A, Mayes MD, Sharif R, Nair DK, Fishbach M, Nguyen N, Reveille JD, Gonzalez EB, McNearny TA. Predictors of fatigue severity in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort. PLoS ONE 6(10): e26061. doi:10.1371/journal.pone.0026061. PubMed
  42. Sharif R, Fritzler MJ, Mayes MD, Gonzalez EB, McNearney TA, Draeger H, Baron M, Canadian Scleroderma Research Group, Furst DE, Khanna DK, Del Junco DJ, Molitor JA, Schiopu E, Phillips K, Seibold JR, Silver RM, Simms RW, GENISOS Study Group, Perry M, Rojo C, Charles J, Zhou X, Agarwal SK, Reveille JD, Assassi S, Arnett FC. Anti-fibrillarin antibody in African American patients with systemic sclerosis: Immunogenetics, clinical features and survival analysis. J Rheumatol. 2011Aug;38(8):1622-30. doi: 10.3899/jrheum.110071. PubMed
  43. Sharif R, Mayes MD, Nicassio PM, Gonzalez EB, Draeger H, McNearney TA, Estrada-Y-Martin RM, Nair DK, Reveille JD, Arnett FC, Assassi S; GENISOS Study Group. Determinants of work disability in patients with systemic sclerosis: A longitudinal study of the GENISOS cohort. Semin Arthritis Rheum. 2011 Aug;41(1):38-47. doi: 10.1016/j.semarthrit.2011.01.002. PubMed
  44. Coustet B, Agarwal SK, Gourh P, Guedj M, Mayes MD, Dieude P, Wipff J, Avouac J, Hachulla E, Diot E, Cracowski JL, Tiev K, Sibilia J, Mouthon L, Frances C, Amoura Z, Carpentier P, Meyer O, Kahan A, Boileau C, Arnett FC, Allanore Y. Association study of ITGAM, ITGAX and CD58 autoimmune risk loci in systemic sclerosis: results from two large European Caucasian cohorts. J Rheumatol. 2011 Jun;38(6):1033-8. PubMed
  45. Agarwal SK, Wu M, Livingston CK, Parks DH, Mayes MD, Arnett FC and Tan FK. Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts. Arthritis Res Ther. 2011 Jan 11;13:R3 PubMed
  46. Diaz-Gallo LM, Gourh P, Broen J, Simeon C, Fonollosa V, Ortego-Centeno N, Agarwal S, Vonk MC, Coenen M, Riemekasten G , Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assassi S, García-Hernandez FJ, Carreira P, Camps MT, Fernandez-Nebro A, de la Peña PG, Nearney T, Hilda D, González-Gay MA, Airo P, Beretta L, Scorza R, Herrick A, Worthington J, Pros A, Gómez-Gracia I, Trapiella L, Espinosa G, Castellvi I, Witte T, de Keyser F, Vanthuyne M, Mayes MD, Radstake TR, Arnett FC, Martin J, Rueda B. Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis. Ann Rheum Dis. 2011 70(3):454-62. PubMed
  47. Nguyen B, Mayes MD, Arnett FC, Del Junco D, Reveille JD, Gonzalez EB, Draeger HT, Perry M, Hendiani A, Anand KK, Assassi S. HLA-DRB1*0407 and *1304 are risk factors for scleroderma renal crisis. Arthritis Rheum. 2011 Feb;63(2):530-4. PubMed
  48. Assassi S, Reveille JD, Arnett FC, Weisman MH, Ward MM, Agarwal SK, Gourh P, Bhula J, Sharif R, Sampat K, Mayes MD, Tan FK. Whole-blood gene expression profiling in ankylosing spondylitis shows upregulation of toll-like receptor 4 and 5. J Rheumatol. 2011 Jan;38(1):87-98. PubMed
  49. Assassi S, Sharif R, Lasky RE, McNearney TA, Estrada-Y-Martin RM, Draeger H, Nair DK, Fritzler MJ, Reveille JD, Arnett FC, Mayes MD; GENISOS Study Group. Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort. Arthritis Res Ther. 2010; 12(5):R166. PubMed
  50. McNearney TA, Sluka KA, Ahn C, Reveille JD, Fischbach M, Mayes, MD. Plasma endogenous enkephalin levels in early systemic sclerosis: clinical and laboratory associations. Clin Exp Rheum 2010 Mar-Apr;28(2 Suppl 58):S7-11. PubMed
  51. Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, Coenen MJ, Vonk MC, Voskuyl AE, Scheurwegh AJ, Broen JC, van Riel PL, van 't Slot R, Italiaander A, Ophoff RA, Riemekasten G, Hunzelmann N, Simeon CP, Ortego-Centeno N, González-Gay MA, González-Escribano MF; Spanish Scleroderma Group, Airo P, van Laar J, Herrick A, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels P, Westhovens R, Kreuter A, Kiener H, de Baere E, Witte T, Padykov L, Klareskog L, Beretta L, Scorza R, Lie BA, Hoffmann-Vold AM, Carreira P, Varga J, Hinchcliff M, Gregersen PK, Lee AT, Ying J, Han Y, Weng SF, Amos CI, Wigley FM, Hummers L, Nelson JL, Agarwal SK, Assassi S, Gourh P, Tan FK, Koeleman BP, Arnett FC, Martin J, Mayes MD. Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet. 2010 May;42(5):426-9. PubMed
  52. Arora-Singh RK, Assassi S, Del Junco DL, Arnett FC, Perry M, Irfan U, Sharif R, Mattar T, Mayes MD. Autoimmune diseases and autoantibodies in the first degree relatives of patients with systemic sclerosis. J Autoimmun 2010 Aug;35(1):52-7. PubMed
  53. Gourh P, Agarwal SK, Martin E, Divecha D, Rueda B, Bunting H, Assassi S, Paz G, Shete S, McNearney T, Draeger H, Reveille JD, Radstake TR, Simeon CP, Rodriguez L, Vicente E, Gonzalez-Gay MA, Mayes MD, Tan FK, Martin J, Arnett FC. Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations. J Autoimmun 2010 Mar;34(2):155-62. PubMed
  54. Rueda B, Gourh P, Broen J, Agarwal SK, Simeon C, Ortego-Centeno N, Vonk MC, Coenen M, Riemekasten G, Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assassi S, Garcia-Hernandez FJ, Carreira P, Camps M, Fernandez-Nebro A, Garcia de la Peña P, McNearney T, Draeger H, Gónzalez-Gay MA, Airo P, Beretta L, Scorza R, Radstake TR, Mayes MD, Arnett FC, Martin J. BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians. Ann Rheum Dis 2010 Apr;69(4):700-5. PubMed
  55. McNearney TA, Sallam HS, Hunnicutt SE, Doshi D, Wollaston DE, Mayes MD, Chen JD. Gastric slow waves, gastrointestinal symptoms and peptides in systemic sclerosis patients. Neurogastroenterol Motil. 2009 Dec;21(12):1269-e120. PubMed
  56. Gourh P, Arnett FC, Assassi S, Tan FK, Huang M, Diekman L, Mayes MD, Reveille JD, Agarwal SK. Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations. Arthritis Res Ther. 2009;11(5):R147. PubMed
  57. Cockrill T, del Junco DJ, Arnett FC, Assassi S, Tan FK, McNearney T, Fischbach M, Perry M, Mayes MD. Separate influences of birth order and gravidity/parity on the development of systemic sclerosis. Arthritis Care Res (Hoboken). 2010 Mar;62(3):418-24. PubMed
  58. Broen J, Gourh P, Rueda B, Coenen M, Mayes M, Martin J, Arnett FC, Radstake TR, European Consortium on Systemic Sclerosis Genetics. The FAS -670A>G polymorphism influences the susceptibility to systemic sclerosis phenotypes. Arthritis Rheum 2009 Dec;60(12):3815-20. PubMed
  59. Zhou X, Lee JE, Arnett FC, Xiong M, Park MY, Yoo YK, Shin ES, Reveille JD, Mayes MD, Kim JH, Song R, Choi JY, Park JA, Lee YJ, Lee EY, Song YW, Lee EB. HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: A genome-wide association study in Koreans with replication in North Americans. Arthritis Rheum 2009 Dec;60(12):3807-14. PubMed
  60. Assassi S, Mayes MD, Arnett FC, Gourh P, Agarwal SK, McNearney TA, Chaussabel D, Oommen N, Fischbach M, Shah KR, Charles J, Pascual V, Reveille JD, Tan FK. Systemic sclerosis and lupus: points in an interferon-mediated continuum. Arthritis Rheum 2010 Feb;62(2):589-98. PubMed
  61. Gourh P, Arnett FC, Tan FK, Assassi S, Divecha D, Paz G, McNearney T, Draeger H, Reveille JD, Mayes, MD, Agarwal SK. Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis. Ann Rheum Dis 2010 Mar;69(3):550-5. PubMed
  62. Karp DR, Marthandan N, Marsh SG, Ahn C, Arnett FC, DeLuca DS, Diehl AD, Dunivin R, Eilbeck K, Feolo M, Guidry PA, Helmberg W, Lewis S, Mayes MD, Mungall C, Natale DA, Peters B, Petersdorf E, Reveille JD, Smith B, Thomson G, Waller MJ, Scheuermanm RH. Novel sequence feature variant type analysis of the HLA genetic association in systemic sclerosis. Hum Mol Genet 2010 Feb 15;19(4):707-19. PubMed
  63. Arnett FC, Gourh P, Shete S, Ahn CW, Honey RE, Agarwal SK, Tan FK, McNearney T, Fischbach M, Fritzler MJ, Mayes MD, Reveille JD. Major histocompatibility complex (MHC) class II alleles, haplotypes, and epitopes which confer susceptibility or protection in systemic sclerosis: Analyses in 1300 Caucasian, African-American and Hispanic cases and 1000 controls. Ann Rheum Dis 2010May;69(5):822-7. PubMed
  64. Agarwal SK, Gourh P, Shete S, Paz G, Divecha D, Reveille JD, Assassi S, Tan FK, Mayes MD, Arnett FC. Association of interleukin23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis. J Rheumatol 2009 Dec;36(12):2715-23. PubMed
  65. Assassi S, Del Junco D, Sutter K, McNearney TA, Reveille JD, Karnavas A, Gourh P, Estrada-Y-Martin RM, Fischbach M, Arnett FC, Mayes, MD. Clinical and genetic factors predictive of mortality in early systemic sclerosis. Arthritis Rheum 2009 Oct 15;61(10):1403-11. PubMed
  66. Gourh P, Agarwal SK, Divecha D, Assassi S, Paz G, Arora-Singh RK, Reveille JD, Shete S, Mayes MD, Arnett FC, Tan FK. Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: Evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines. Arthritis Rheum 2009 Dec;60(12):3794-806. PubMed
  67. Assassi S, Fritzler MJ, Arnett FC, Norman GL, Shah KR, Gourh P, Manek N, Perry M, Ganesh D, Rahbar MH, Mayes MD. Primary biliary cirrhosis (PBC), PBC autoantibodies, and hepatic parameter abnormalities in a large population of systemic sclerosis patients. J Rheumatol 2009 Oct;36(10):2250-6. PubMed
  68. Assassi S, Arnett FC, Reveille JD, Gourh P, Mayes MD. Clinical, immunological, and genetic features of familial systemic sclerosis. Arthritis Rheum 2007 Jun;56(6):2031-7. PubMed
  69. Suarez-Almazor ME, Kallen MA, Roundtree AK, Mayes M. Disease and symptom burden in systemic sclerosis: a patient perspective. J Rheumatol 2007 Aug;34(8):1718-26. PubMed
  70. Alkassab F, Gourh P, Tan FK, McNearney T, Fischbach M, Ahn C, Arnett FC, Mayes MD. An allograft inflammatory factor 1 (AIF1) single nucleotide polymorphism (SNP) is associated with anticentromere antibody positive systemic sclerosis. Rheumatology (Oxford) 2007 Aug; 46(8):1248-51. PubMed
  71. Gourh P, Tan FK, Assassi S, Ahn CW, McNearney TA, Fischbach M, Arnett FC, Mayes, MD. Association of the PTPN22 R620W polymorphism with anti-topoisomerase-I and anticentromere antibody-positive systemic sclerosis. Arthritis Rheum 2006 Dec;54(12):3945-53. PubMed
  72. McNearney TA, Reveille JD, Fischbach M, Friedman AW, Lisse JR, Goel N, Tan FK, Zhou X, Ahn C, Feghali-Bostwick CA, Fritzler M, Arnett FC, Mayes MD. Pulmonary involvement in systemic sclerosis: Associations with genetic, serologic, sociodemographic, and behavioral factors. Arthritis Rheum 2007 Mar 15;57 (2):318-26. PubMed
  73. Wu SP, Leng L, Feng Z, Liu N, Zhao H, McDonald C, Lee A, Arnett FC, Gregersen PK, Mayes MD, Bucala R. Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum 2006 Nov;54(11):3661-9. PubMed
  74. Gardner H, Shearstone JR, Bandaru R, Crowel T, Lynes M, Trojanowska M, Pannu J, Smith E, Jablonska S, Blaszczyk M, Tan FK, Mayes MD. Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts. Arthritis Rheum 2006 Jun;54(6):1961-73. PubMed
  75. Tan FK, Zhou X, Mayes MD, Gourh P, Guo X, Marcum C, Jin L, Arnett FC,Jr. Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients. Rheumatology (Oxford) 2006 Jun;45(6):694-702. PubMed
  76. Assassi S, Mayes MD, McNearney T, Fischbach M, Reveille JD, Arnett FC, Tan FK. Polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in systemic sclerosis. Am J Med 2005 Aug;118(8):907-11. PubMed
  77. Chatterjee S, Dombi GW, Severson RK, Mayes MD. Risk of malignancy in scleroderma: a population-based cohort study. Arthritis Rheum 2005 Aug;52(8); 2415-24. PubMed
  78. Tan FK, Hildebrand BA, Lester MS, Stivers DN, Pounds S, Zhou X, Wallis DD, Milewicz DM, Reveille JD, Mayes MD, Jin L, Arnett FC Jr. Classification analysis of the transcriptosome of nonlesional cultured dermal fibroblasts from systemic sclerosis patients with early disease. Arthritis Rheum 2005 Mar; 52(3):865-76. PubMed
  79. Mayes MD, Lacey JV Jr, Beebe-Dimmer J, Gillespie BW, Cooper B, Laing TJ, Schottenfeld D. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large U.S. population. Arthritis Rheum 2003;48(8):2246-55 PubMed