CLOVERS
Crystalloid Liberal Or Vasopressors Early Resuscitation In Sepsis
Project Summary
To determine the impact of a restrictive fluids strategy (vasopressors first followed by rescue fluids) as compared to a liberal fluid strategy (fluids first followed by rescue vasopressors) on 90-day in-hospital mortality in patients with sepsis-induced hypotension.
Population:
Adult septic and hypotensive patients who are seeking care in the emergency department.
Outcomes:
Measure patient-centered outcomes caused by markedly different initial resuscitation strategies.
Enrollment:
Began September 2018, 25 patients enrolled as of December 2019
Study Team:
Pratik Doshi, MD, CMQ| Ryan Huebinger, MD | Vishal Demla, MD| Richard Gordon, MD | Benjamin Karfunkle, MD | Shabana Walia, MD| Elizabeth Vidales (Research Coordinator)| Emergency Medicine Research Assistants.