ICECAP

Influence of Cooling duration on Efficacy in Cardiac Arrest Patients

Project Summary:

To characterize the duration response curve for hypothermia and determine in each of two populations: The shortest duration of cooling that provides the maximal treatment effect and whether the duration-response implies efficacy versus no cooling

Population:

Comatose adult survivors of out of hospital cardiac arrest that have already been rapidly cooled using a definitive temperature control method. Sample size 1800 subjects

Outcomes:

Modified Rankin scale (mRS) at 90 days after return of spontaneous circulation.

Enrollment:

Preparing for enrollment 2020

Study Team:

Misty Ottman BSN, CCRP |Pratik Doshi, MD, CMQ | Henry Wang, MD, MPH, MS | Ryan Huebinger, MD