Publications

Jeson J Li, Nan Xin, Chunxia Yang, Larrisa A Tavizon, Ruth Hong, Travis I Moore, Rebecca G Tharyan, Adam Antebi, Hyun-Eui Kim. Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response (MERSR) and its Impact on Proteostasis. BioRxiv, 2023 Sept 8. doi: https://doi.org/10.1101/2023.09.07.556674.

Sukyeong Lee, Sang Bum Lee, Nuri Sung, Wendy Xu, Changsoo Chang, Hyun-Eui Kim, Andre Catic, Francis Tsai. Structural Basis of Impaired Disaggregase Function in the Oxidation-sensitive SKD3 Mutant Causing 3-Methylglutaconic Aciduria. Nat Comm, 2023 Apr 11;14(1):2028. doi: 10.1038/s41467-023-37657-9.

Xin N, Durieux J, Yang C, Wolff S, Kim H*, Dillin A*. The UPRmt Preserves Mitochondrial Import to Extend Lifespan. Journal of cell biology, 2022 Jul 4;221(7):e202201071. doi: 10.1083/jcb.202201071. * co-correspondence

Shengxin Li, Hyun-Eui Kim. Implications of Sphingolipids on Aging and Age-Related Diseases. Frontiers in aging, 2022 March; 2:797320, doi: 10.3389/fragi.2021.797320.

Jian Xiong, Jingquan He, Wendy P. Xie, Ezekiel Hinojosa, Chandra Shekar R. Ambati, Nagireddy Putluri, Hyun-Eui Kim, Michael X. Zhu, Guangwei Du. Rapid affinity purification of intracellular organelles using a twin strep tag. J Cell Sci, 2019 Dec 13;132(24).

Kim HE, Grant AR, Simic MS, Kohnz RA, Nomura DK, Durieux J, Riera CE, Sanchez M, Kapernick E, Wolff S, Dillin A. Lipid biosynthesis coordinates the Mitochondrial to Cytosolic Stress Response. Cell, 2016 Sept 6; 166(6): 1539-1552.

Berendzen, K, Durieux J, Shao LW, Tian Y, Kim HE, Wolff S, Liu Y, Dillin A. Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis. Cell, 2016 Sept 6; 166(6): 1553-1563.

Du D, Murray E, Cohen E, Kim HE, Simkovsky R, Dillin A, Kelly JW. A kinetic aggregation assay that enables highly sensitive A-beta semiquantification in cells and tissues. Biochemistry. 2011 Mar 15; 50(10): 1067-17.

Van Ham TJ, Homberg M, Van der Goot A, Teuling E, Garcia-Arencibia M, Kim HE, Du D, Van Bergeijk, Thijssen KL, Wiersma M, Burggraaff R, van Rheenen J, van Veluw GJ, Hofstra R MW, Rubinsztein DC, Nollen E AA. Identification of Moag-4/SERF as a regulator of age-related proteotoxicity. Cell. 2010 Aug 20;142(4): 601-612.

Kim HE, Wang X. CAS and PHAPI Positively Regulate Apoptosome formation by Enhancing Nucleotide Exchange on Apaf-1. Mol. Cell. 2008 Apr 24; 30(2): 239-47.

Kim HE, Du F, Fang M, Wang X. Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1. Proc Natl Acad Sci U S A. 2005 Dec 6; 102(49): 17545-17550.

Liu Q, Rand TA, Kalidas S, Du F, Kim HE, Smith DP, Wang X. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science. 2003 Sep 26;301(5641): 1921-5.

Jiang X, Kim HE, Shu H, Zhao Y, Zhang H, Kofron J, Donnelly J, Burns D, Ng SC, Rosenberg S, Wang X. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science. 2003 Jan 10;299(5604): 223-6.

Kim HE, Yoon SY, Lee JE, Choi WS, Jin BK, Oh TH, Markelonis GJ, Chun SY, Oh YJ. MPP(+) downregulates mitochondrially encoded gene transcripts and their activities in dopaminergic neuronal cells: protective role of Bcl-2. Biochem Biophys Res Commun. 2001 Aug 24;286(3): 659-65.

Kim HE, Oh JH, Lee SK, Oh YJ. Ginsenoside RH-2 induces apoptotic cell death in rat C6 glioma via a reactive oxygen- and caspase-dependent but Bcl-X(L)-independent pathway. Life Sci. 1999;65(3): PL33-40.

Joo CK, Cho KS, Kim HE, Choi JS, Oh YJ. Protective role for Bcl-2 in experimentally induced cell death of bovine corneal endothelial cells. Ophthalmic Research. 1999: 31(4): 287-96.