Overview

The Department of Integrative Biology and Pharmacology (IBP) is interested in the cell biology, physiology and pharmacology of cell regulation and communication. Our major research themes include the molecular mechanisms and spatiotemporal dynamics of membrane signaling, intracellular and metabolic signaling, the biology and physiology of cell-cell interactions, and the use of computational, structural and systems approaches to decipher signaling networks.

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Upcoming Events & Seminars

October 22, 2018 IBP SEMINAR SERIES from 4:00pm to 5:00pm MSB 2.135 "Axons as a Barrier to Mitochondrial Transport" Neal Waxham, Ph.D. Professor UTHealth Questions? Contact Patricia.McFarland@uth.tmc.edu October 29, 2018 IBP SEMINAR SERIES from 4:00pm to 5:00pm MSB 2.135 "Keeping things straight: Mechanisms of spine stability and cartilage homeostatis" Ryan S. Gray, Ph.D. Assistant Professor The University of Texas at Austin Questions? Contact Patricia.McFarland@uth.tmc.edu November 5, 2018 IBP SEMINAR SERIES from 4:00pm to 5:00pm MSB 2.135 "TBA"
Guang Peng, M.D., Ph.D.
Associate Professor
M.D. Anderson Cancer Center, The University of Texas Health Science Center, Houston

Questions? Contact Patricia.McFarland@uth.tmc.edu
November 12, 2018 IBP SEMINAR SERIES from 4:00pm to 5:00pm MSB 2.135 "Novel mutations in human SLC12A transporters: Challenges of unique clinical cases" Eric Delpire, Ph.D. Professor Vanderbilt University Questions? Contact Patricia.McFarland@uth.tmc.edu November 19, 2018 IBP SEMINAR SERIES from 4:00pm to 5:00pm MSB 2.135 "TBA" Jason T Yustein, M.D., Ph.D. Assistant Professor Baylor College of Medicine Questions? Contact Patricia.McFarland@uth.tmc.edu

Recent Faculty Publications

  • Akhmedov D, Mendoza Rodriguez MG, Rajendran K, Rossi M, Wess J and Berdeaux R.  (2017).  Gs-DREADD knock-in mice for tissue-specific, temporal stimulation of cAMP signalingMol Cell Biol. 2017 Apr 14;37(9). pii: e00584-16. doi: 10.1128/MCB.00584-16. Print May 1.
  • Armstrong TS, Vera E, Zhou R, Acquaye AA, Sullaway CM, Berger A, Breton G, Mahajan A, Wefel JS, Gilbert MR and Scheurer M. (2017).  Association of Genetic Variants with Fatigue in Patients with Malignant Glioma. Neuro-Oncology Practice. In press.
  • Bonaldi K, Li Z, Kang SE, Breton G, Pruneda-Paz JL. (2017).  Novel cell surface luciferase reporter for high-throughput quantitative yeast one-hybrid screens. Nucleic Acids Res.  Jul 31. doi: 10.1093/nar/gkx682. [Epub ahead of print].
  • Burns M, Wisser K, Wu J, Levental I, Veatch SL. (2017). Miscibility Transition Temperature Scales with Growth Temperature in a Zebrafish Cell Line. Biophys J., May 25. pii: S0006-3495(17)30505-2. doi: 10.1016/j.bpj.2017.04.052.
  • Cornell CE, McCarthy NLC, Levental KR, Levental I, Brooks NJ, Keller SL. (2017).  n-Alcohol Length Governs Shift in Lo-Ld Mixing Temperatures in Synthetic and Cell-Derived Membranes. Biophys J.  Sep 19;113(6):1200-1211. doi: 10.1016/j.bpj.2017.06.066. Epub 2017 Aug 9.
  • Daquinag AC, Dadbin A, Snyder B, Wang X, Sahin AA, Ueno NT, Kolonin MG. (2017). Non-glycanated Decorin Is a Drug Target on Human Adipose Stromal Cells. Mol Ther Oncolytics. May 17;6:1-9. doi: 10.1016/j.omto.2017.05.003. eCollection Sep 15.