Research

Mitochondrial Stress Response We investigate how mitochondria, the powerhouses of the cell, manage stress to maintain protein homeostasis. Our research delves into the signaling pathways that enable mitochondria to adapt to stress, ensuring cellular function and survival. By understanding these pathways, we aim to identify potential therapeutic targets for diseases marked by mitochondrial dysfunction.

Cross-Compartmental Communication Our lab explores the intricate communication networks between different cellular compartments under stress. We study how stress responses in mitochondria interact with other organelles, such as the endoplasmic reticulum (ER), and how these interactions influence overall cellular health. This research area provides insight into how cells coordinate responses to maintain stability and function, even in challenging conditions.

Aging and Age-Related Diseases We focus on the role of mitochondrial dysfunction in aging and age-related diseases, including Alzheimer’s, Parkinson’s, and Huntington’s disease. By examining the cellular and molecular mechanisms that link mitochondrial health to neurodegeneration, we aim to identify factors that could be targeted to slow disease progression and enhance quality of life in aging populations.