Publications
Selected Publications
Dumbali SP, Horton PD, Moore TI, Wenzel PM. (2024). Mitochondrial permeability transition dictates mitochondrial maturation in hematopoietic precursors. Communications Biology, 7(1):967. PMID: 39122870.
Mise K, Long J, Galvan D, Ye Z, Fan G, Serysheva II, Moore TI, Wada J, Schumacker PT, Chang BH and Danesh FR. (2024) Improving Mitochondrial Respiration as a Strategy to Prevent Diabetic Kidney Disease Progression. Nature Communications. PMID: 37461606.
Zhu X*, Qi C*, Wang R*, Lee JH*, Shao J, Lanxin B. Xiong F, Nguyen PT, Li G, Krakowiak J, Koh S, Simon L, Han L, Moore TI, Li W. (2022). Acute Depletion of Human Core Nucleoporin Reveals Direct Roles in Transcription Control but Dispensability for 3D Genome Organization. Cell Reports. 41(5) 111576. PMID: 36323253.
Moore TI, Aaron J, Chew TL, and Springer TA, Measuring integrin conformational change on the cell surface with super-resolution microscopy. (2019) Cell Reports, 22 (7), 1903–1912. PMID: 29444440.
Moore TI*, Nordenfelt P*, Mehta SB*, Matthew JK, Swaminathan S, Nobuyasu K, Lambert TJ, Baker D, Waters JC, Oldenbourg R, Tani T, Mayor S, Waterman CM and Springer TA. (2017). Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration. Nature Communications, 8(1), 673. PMID: 29229906.
Swaminathan V*, Matthew JK*, Mehta SB*, Nordenfelt P, Moore TI, Nobuyasu K, Baker D, Oldenbourg R, Tani T, Mayor S, Springer TA and Waterman CM. (2017). Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions. PNAS, 114(40) 40648-10653. PMID: 29073038.
Moore TI*, Chou CS*, Nie Q, and Yi TM. Alternative cell polarity behaviors arise from bifurcations in G-protein spatial dynamics. (2015). IET Systems Biology, 9(2) 52-63. PMID: 26029251.
Moore TI, Tanaka H, Kim KJ, Jeon NL, and Yi TM. (2013). Yeast G-proteins mediate directional sensing and polarization behaviors in response to changes in pheromone gradient direction. Molecular Biology of the Cell, 24(4) 521-534. PMID: 23255559.
Quinones GA, Moore TI, Nicholes K, Lee H, Sun L, Jeon NL, and Stephan JP. (2013) New wall-less plate technology enabling cell-based investigations. Blood, 21(7) 25-35. PMID: 23242998.
Moore TI*, Chou CS*, Chang S, Nie Q, and Yi TM. (2012) Signaling regulated endocytosis and exocytosis lead to mating pheromone concentration dependent morphologies in yeast. FEBS letters. 586(23). PMID: 23108052.
Moore TI, Chou CS, Jeon NL, Nie Q, and Yi TM. (2008) Robust spatial sensing of mating pheromone gradients by yeast cells. PLoS One, 3, e3865. PMID: 19052645.
Waksman R, McEwan PE, Moore TI, Kolodige FD, Hellinga DG, Seabron RC, Rychnovsky S, Vasek J, Scott RW, Virmani R. (2008) PhotoPoint photodynamic therapy promotes stabilization of atherosclerotic plaques and inhibits plaque progression. Journal of the American College of Cardiology, 52, 1024-1032. PMID: 18786486.
Deane JD, Kharas MG, Oak JS, Stiles LN, Luo J, Moore TI, Ji H, Rommel C, Cantley LC, Lane TE, and Fruman DA. (2007) T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling. Blood. 109, 2894-2902. PMID: 17164340.
Hess KL, Donahue AC, Ng KL, Moore TI, Oak J, and Fruman DA. (2004). Frontline: The p85alpha isoform of phosphoinositide 3-kinase is essential for a subset of B cell receptor-initiated signaling responses. European Journal of Immunology. 34, 2968-2976. PMID: 15384044.