Hereditary Cancer Syndromes & Genetic Counselling
Our Center offers comprehensive services for evaluation and management of hereditary and familial gastrointestinal (GI) cancer syndromes with appropriate genetic counseling. Patients and families are at high risk of developing GI cancers including colorectal, pancreatic, gastric and small intestinal due to certain genetic mutations.
Patients who have personal or family history of one of the following are encouraged to visit our clinic:
- Diagnosis of colorectal cancer before the age of 50 years
- History of multiple colonic polyps
- History of multiple GI polyps (non-colorectal)
- Family history of pancreatic cancer
- Two or more primary GI cancers
- Early onset diagnosis of stomach and non-colorectal GI cancers
- Family or personal history breast or uterine cancers
We recommend patients and their families to undergo comprehensive evaluation and risk assessment in our clinic when they have mutation in certain genes associated with the following cancer syndromes:
- Lynch syndrome (also previously known as hereditary non-polyposis colorectal syndrome or HNPCC)
- Familial adenomatous polyposis (FAP) syndrome
- MUTYH (or MYH)-associated polyposis (MAP) syndrome
- Peutz-Jegher’s syndrome
- Juvenile polyposis syndrome
- Familiar pancreatic cancer
- Hereditary diffuse gastric cancer (HDGC) syndrome
Following services are offered for high-risk patients and their families with hereditary and familial GI cancers:
- GI cancer prevention genetic counseling
- GI cancer risk assessment and genetic testing
- Comprehensive GI endoscopic procedures-diagnostic and therapeutic
- Minimally invasive surgical procedures
- GI cancer prevention strategies including participation in clinical and translational research