Research

Ayala Lab in Action

The research in Dr. Ayala’s laboratory focuses on understanding cancer biology through both experimental and clinical pathology approaches. His team studies how tumors develop, progress, and interact with their surrounding microenvironment, with a strong emphasis on nerve–tumor interactions and mechanisms of metastasis.

The lab integrates molecular pathology, translational research, and advanced laboratory techniques to investigate how cancer cells communicate with surrounding tissues. By combining clinical data with laboratory findings, the team aims to uncover key biological pathways that drive cancer progression and resistance to therapy.

A major focus of the lab is exploring perineural invasion and neuroepithelial interactions in cancer, helping to better understand how tumors spread along nerves and how these processes can be targeted for treatment.

Through these efforts, Dr. Ayala’s lab seeks to improve early detection, refine diagnostic methods, and contribute to the development of more effective, targeted cancer therapies that ultimately enhance patient outcomes.