New Grants FY 2024

April

Baylor College of Medicine

Title: Gulf Coast Consortia / Houston Area Molecular BioPhysics Pre-Doctoral Fellowship
Principal Investigator: Paula Antonia Bender
Department/Division: Biochemistry and Molecular Biology
Period of Support: 11/1/2023–10/31/2024
Total Direct Costs: $35,788.00

American Heart Association

Title: Associating vascular transformation/fibrinolysis markers and neuropsychiatric sequelae in long COVID-19
Principal Investigator: Vijayasree Vayalanellore Giridharan
Department/Division: Psychiatry & Behavioral Science
Period of Support: 4/1/2024–3/31/2026
Total Direct Costs: $149,764.00

Academy Health

Title: Exploring Consumer and Patient Internet Search and Activity Related to the Diagnosis, Pathways to Care and Outcomes for Alcohol Use Disorder
Principal Investigator: Jane E Hamilton
Department/Division: Psychiatry & Behavioral Science
Period of Support: 4/1/2024–3/31/2025
Total Direct Costs: $68,127.00

American Heart Association

Title: Regulation of systemic pH balance by renal Epac isoforms
Principal Investigator: Kyrylo A Pyrshev
Department/Division: Integrative Biology Pharmacology
Period of Support: 9/1/2024–8/31/2027
Total Direct Costs: $272,727.00

The University of Texas Health Science Center at San Antonio

Title: Role of Neutrophil-derived Hypoxia-Inducible Factor 1 Alpha in Liver Injury (TRC4)
Principal Investigator: Yankai Wen
Department/Division: Anesthesiology
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $90,909.00

The University of Texas Health Science Center at San Antonio

Title: Investigation of the therapeutic potential of eosinophils to attenuate trauma and combat casualty-related liver injury (TRC4)
Principal Investigator: Changqing Ju
Department/Division: Anesthesiology
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $447,990.00

The University of Texas Health Science Center at San Antonio

Title: A novel protective role of eosinophil-specific Cox-2 in hepatic ischemia and reperfusion injury (TRC4)
Principal Investigator: Yang Yang
Department/Division: Anesthesiology
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $181,818.00

National Institute of General Medical Sciences

Title: Biological and structural diversity of bacterial type IV secretion systems
Principal Investigator: Peter J. Christie
Department/Division: Microbiology and Molecular Genetics
Period of Support: 5/1/2024–2/28/2029
Total Direct Costs: $1,545,000.00

Gulf Coast Consortium

Title: Cancer Therapeutics Training Program
Principal Investigator: Yin Yuen Ha
Department/Division: IMM, Texas Therapeutic Institute
Period of Support: 8/1/2023–7/31/2024
Total Direct Costs: $82,449.00

University of Virginia

Title: Decoding the Molecular and Cellular Mechanisms of Mutant KRAS-driven Brain Arteriovenous Malformations
Principal Investigator: Sean Paul Marrelli
Department/Division: Neurology
Period of Support: 12/1/2023–11/30/2025
Total Direct Costs: $17,926.00

The University of Texas Health Science Center at San Antonio

Title: Prevention of Hemorrhagic Shock-induced Acute Kidney Injury by Targeting Hypoxia-sensitive ATP4A with Pantoprazole: A Prospective Randomized Controlled Trial (TRC4)
Principal Investigator: Yafen Liang
Department/Division: Anesthesiology
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $454,545.00

Reach Out Read National Center

Title: ROAR core program in Lubbock, Potter, Randall and Swisher Counties
Principal Investigator: Jocelyn M McConnell
Department/Division: Pediatrics, Childrens Learning Institute
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $40,000.00

The University of Texas Health Science Center at San Antonio

Title: Hemodynamic management following acute traumatic spinal cord injury: A pilot randomized, controlled trial (TRC4)
Principal Investigator: David E Meyer
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $266,828.00

The University of Texas Health Science Center at San Antonio

Title: Freeze Dried Mechotransduced MSC Derived Exosomes for Neurological Injury (TRC4)
Principal Investigator: Charles S Cox Jr
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $454,420.00

The University of Texas Health Science Center at San Antonio

Title: An Assessment of Green Plasma: The Prevalence of, Quantification of “Green-ness,” and Potential Hemostatic Superiority of a Currently Discarded Blood Product
Principal Investigator: Bryan A Cotton
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $411,357.00

The University of Texas Health Science Center at San Antonio

Title: Pediatric Prospective Observational Vascular Injury Trial
Principal Investigator: Natalie Atkinson Drucker
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $167,702.00

The University of Texas Health Science Center at San Antonio

Title: Assessment of the Relationship between Statins, Microvascular Dysregulation, and Venous Thromboembolism in Severely Injured Trauma Patients
Principal Investigator: Gabrielle Elise Hatton
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $214,883.00

National Institute of Dental and Craniofacial Research

Title: A signaling crosstalk regulation in neural crest-derived cranial suture
Principal Investigator: Xiaolei Zhao
Department/Division: Pediatrics, Research Center
Period of Support: 4/8/2024–3/31/2026
Total Direct Costs: $99,582.00

Johns Hopkins University

Title: PO versus IV antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
Principal Investigator: Stephen Warner
Department/Division: Orthopaedics Surgery
Period of Support: 9/30/2022–9/29/2026
Total Direct Costs: $48,478.00

National Institute of Neurological Disorders and Stroke

Title: Pathobiology of ICH in Aging
Principal Investigator: Joo Eun Jung
Department/Division: Neurology
Period of Support: 4/12/2024–1/31/2029
Total Direct Costs: $1,645,035.00

Welch Foundation

Title: Structural characterization of a Chimeric Antigen Receptor and its interactions with tumor associated antigens
Principal Investigator: Matthew Lowell Baker
Department/Division: Biochemistry and Molecular Biology
Period of Support: 6/1/2024–5/31/2027
Total Direct Costs: $300,000.00

The University of Texas Health Science Center at San Antonio

Title: Novel ‘Short Wave Assessment Tool in Texas’ to enhance burn tissue viability assessment
Principal Investigator: John Harvin
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $27,500.00

University of Texas Health Science Center at San Antonio

Title: Improving Veteran Functioning with Intensive Transdiagnostic CBT for Anxiety
Principal Investigator: Charles Green
Department/Division: Center for Clinical Research and Evidence-Based Medicine
Period of Support: 1/1/2024–6/30/2024
Total Direct Costs: $18,105.00

University of Washington

Title: Linking Retinal Circuits to Perception
Principal Investigator: David W. Marshak
Department/Division: Neurobiology and Anatomy
Period of Support: 6/1/2023–5/31/2027
Total Direct Costs: $138,538.00

The University of Texas Health Science Center at San Antonio

Title: Identifying SUR1/TRPM4 Polymorphisms to Reduce Contusion Expansion after TBI: Clinical Trial Planning Grant
Principal Investigator: Charles S Cox Jr
Department/Division: Center for Translational Injury Research
Period of Support: 4/1/2024–7/31/2025
Total Direct Costs: $198,967.00

Wellcome Leap

Title: Identifying miRNA Signatures of Opioid Misuse Risk in Trauma Patients
Principal Investigator: Consuelo Walss-Bass
Department/Division: Psychiatry and Behavioral Science
Period of Support: 4/9/2024–3/31/2027
Total Direct Costs: $2,406,503.00

American Association of Hip and Knee Surgeons

Title: FY23-24 Adult Recon AAHKS
Principal Investigator: Kenneth B Mathis
Department/Division: Orthopaedics Surgery
Period of Support: 8/1/2023–7/31/2024
Total Direct Costs: $13,800.00

The University of Texas Southwestern Medical Center

Title: Collaborative Care for Polysubstance use in Primary Care Settings trial
Principal Investigator: Angela L. Stotts
Department/Division: Family and Community Medicine
Period of Support: 3/1/2024–2/28/2025
Total Direct Costs: $394,819.00

Smith & Nephew

Title: Smith & Nephew 2024-25 Ortho Trauma Fellowship Grant
Principal Investigator: Timothy S Achor
Department/Division: Orthopaedics Surgery
Period of Support: 8/1/2024–7/31/2025
Total Direct Costs: $20,000.00

Arthrex, Inc.

Title: Foot and Ankle Arthrex Fellowship FY23/24
Principal Investigator: William C. McGarvey
Department/Division: Orthopaedics Surgery
Period of Support: 4/23/2024–4/22/2025
Total Direct Costs: $20,000.00

National Institute of Neurological Disorders and Stroke

Title: Radiographic markers and therapeutic targets of cerebral edema after SAH
Principal Investigator: HuiMahn Alex Choi
Department/Division: Neurosurgery
Period of Support: 5/1/2024–4/30/2029
Total Direct Costs: $413,023.00

March

National Institute of Allergy & Infectious Diseases

Title: Maternal-infant transfer of microbial modified immunity
Principal Investigator: Yuying Liu
Department/Division: Pediatrics, Gastroenterology
Period of Support: 3/1/2024–1/31/2026
Total Direct Costs: $260,000.00

Cancer Prevention & Research Institute of Texas

Title: Characterization and optimization of novel allosteric KRAS inhibitors
Principal Investigator: Alemayehu Gorfe Abebe
Department/Division: Integrative Biology Pharmacology
Period of Support: 3/1/2024–2/28/2027
Total Direct Costs: $1,006,500.00

Cincinnati Children’s Hospital Medical Center

Title: Xenopus lung development
Principal Investigator: Rachel Katherine Miller
Department/Division: Pediatrics, Research Center
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $100,000.00

Baylor College of Medicine

Title: Texas Medical Center Digestive Diseases Center
Principal Investigator: J Marc Rhoads
Department/Division: Pediatrics, Gastroenterology
Period of Support: 9/15/2023–5/31/2028
Total Direct Costs: $60,785.00

The University of Texas MD Anderson Cancer Center

Title: Comparative Effectiveness of Sequential Pharmacotherapeutic Strategies and Virtually Delivered Treatment to Optimize Smoking Cessation
Principal Investigator: Charles Green
Department/Division: Center for Clinical Research & Evidence-Based Medicine
Period of Support: 1/1/2024–12/31/2028
Total Direct Costs: $129,380.00

Air Force Office of Scientific Research

Title: Lipidomics after severe TBI in a Porcine model
Principal Investigator: Aaron M. Gusdon
Department/Division: Neurosurgery
Period of Support: 3/6/2024–3/5/2025
Total Direct Costs: $16,960.00

National Institutes of Health

Title: 7th International Enteric Nervous System Development Meeting: Connection, Cross-talk and Collaboration
Principal Investigator: Allison L Speer
Department/Division: Pediatric Surgery
Period of Support: 3/7/2024–3/31/2025
Total Direct Costs: $14,250.00

Pacira Pharmaceuticals, Inc.

Title: Spasticity Management Fellowship
Principal Investigator: Sheng Li
Department/Division: Physical Medicine & Rehabilitation
Period of Support: 3/7/2024–6/30/2025
Total Direct Costs: $74,858.00

National Institute of General Medical Sciences

Title: Mechanisms and Regulation of Cell Division in Bacteria
Principal Investigator: William Margolin
Department/Division: Microbiology and Molecular Genetics
Period of Support: 4/1/2024–2/28/2029
Total Direct Costs: $1,695,800.00

American Heart Association

Title: HSF1-driven cholesterol biosynthesis and smooth muscle cell phenotypic modulation in progeria-associated atherosclerosis
Principal Investigator: Abhijnan Chattopadhyay
Department/Division: Internal Medicine, Medical Genetics
Period of Support: 4/1/2024–3/31/2027
Total Direct Costs: $210,000.00

Alzheimer’s Association

Title: Biological validation of MBI as part of the ADRD spectrum
Principal Investigator: Natalia Pessoa Rocha
Department/Division: Neurology
Period of Support: 6/1/2024–5/31/2027
Total Direct Costs: $181,576.00

National Institute of General Medical Sciences

Title: Mechanisms of inositol trisphosphate receptor-mediated calcium signaling
Principal Investigator: Irina I Serysheva
Department/Division: Biochemistry and Molecular Biology
Period of Support: 4/1/2024–1/31/2029
Total Direct Costs: $1,653,000.00

Huntington’s Disease Society of America

Title: The University of Texas Health Science Center at Houston, McGovern Medical School
Principal Investigator: Erin Furr Stimming
Department/Division: Neurology
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $56,000.00

Arthrex, Inc.

Title: Arthrex Trauma Educational Grant 2023-2024
Principal Investigator: Timothy S Achor
Department/Division: Orthopaedic Surgery
Period of Support: 3/14/2024–3/13/2025
Total Direct Costs: $40,000.00

American Heart Association

Title: Genetic Regulation of Embryonic Pacemaking
Principal Investigator: Jun Wang
Department/Division: Pediatrics, Research Center
Period of Support: 4/1/2024–3/31/2025
Total Direct Costs: $9,091.00

Alzheimer’s Association

Title: Impaired Microglial Modulation of Neuronal Function in Alzheimer’s Disease
Principal Investigator: Keran Ma
Department/Division: Neurobiology & Anatomy
Period of Support: 7/1/2024–6/30/2027
Total Direct Costs: $181,817.00

National Institutes of Health

Title: Esophageal gland-mediated immune evasion by the human parasite Schistosoma mansoni
Principal Investigator: Jayhun Lee
Department/Division: Microbiology and Molecular Genetics
Period of Support: 3/21/2024–7/31/2028
Total Direct Costs: $24,242.00

University of Michigan

Title: MS4A in tumor immune regulation and immunotherapy
Principal Investigator: Zhiqiang An
Department/Division: IMM, Texas Therapeutic Institute
Period of Support: 3/5/2024–2/28/2029
Total Direct Costs: $415,000.00

Texas A&M University

Title: Genetic investigations services for Streptococcus equi subspecies equi
Principal Investigator: Chenggang Wu
Department/Division: Microbiology and Molecular Genetics
Period of Support: 4/1/2024–9/1/2024
Total Direct Costs: $9,000.00

February

University of Texas Foundation, Inc.

Title: Reach Out and Read in Fort Bend, Jefferson and Washington Counties
Principal Investigator: Jocelyn M McConnell
Department/Division: Pediatrics, Childrens Learning Institute
Period of Support: 12/8/2023–9/30/2024
Total Direct Costs: $11,364.00

Dexcom, Inc.

Title: Continuous Glucose Monitoring for Screening for Diabetes in Pregnancy: A comparative effectiveness randomized control trial – PRECISE
Principal Investigator: Michal Fishel Bartal
Department/Division: Obstetrics, Gynecology, & Reproductive Sciences
Period of Support: 2/2/2023–2/1/2026
Total Direct Costs: $688,583.00

University of Alabama at Birmingham

Title: Promoting circadian rhythms to optimize gut-to-brain signaling for Alzheimer’s disease
Principal Investigator: Andrew M. Pickering
Department/Division: Integrative Biology Pharmacology
Period of Support: 8/1/2023–7/31/2025
Total Direct Costs: $25,546.00

Feinstein Institute for Medical Research

Title: Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor after Successful Deep Brain Stimulation to the Dentato-Rubro-Thalamic Tract
Principal Investigator: Mya C. Schiess
Department/Division: Neurology
Period of Support: 5/1/2023–4/30/2026
Total Direct Costs: $431,658.00

University of Texas at San Antonio

Title: Combined Therapies with Hemichannel-Targeting Antibodies and FDA-approved Therapies in Treating Breast Cancer Bone Metastasis
Principal Investigator: Zhiqiang An
Department/Division: IMM, Texas Therapeutic Institute
Period of Support: 9/1/2023–8/31/2024
Total Direct Costs: $40,357.00

University of Houston

Title: Objective Classification of Lupus Nephritis
Principal Investigator: Claudia Pedroza
Department/Division: Center for Clinical Research & Evidence-Based Medicine
Period of Support: 8/20/2023–5/31/2028
Total Direct Costs: $110,065.00

Ed Rachal Foundation

Title: Reach Out and Read Program Corpus Christi Area
Principal Investigator: Jocelyn M McConnell
Department/Division: Pediatrics, Childrens Learning Institute
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $31,818.00

National Institute of Arthritis & Musculoskeletal & Skin Diseases

Title: Molecular Profiling of Spinal Disease Progression in Ankylosing Spondylitis
Principal Investigator: Mark Chiawei Hwang
Department/Division: Internal Medicine, Rheumatology
Period of Support: 2/12/2024–1/31/2029
Total Direct Costs: $752,500.00

Autism Speaks Inc.

Title: A pilot test of a culturally adapted treatment for Latino autistic youth transitioning to adulthood
Principal Investigator: Antonio Francisco Pagan
Department/Division: Psychiatry & Behavioral Science
Period of Support: 12/1/2023–11/30/2025
Total Direct Costs: $134,608.00

W.L. Gore & Associates, Inc.

Title: Integrated Vascular Surgery Residents Program
Principal Investigator: Naveed U Saqib
Department/Division: Cardiothoracic & Vascular Surgery
Period of Support: 7/1/2024–6/30/2025
Total Direct Costs: $25,000.00

Joe Niekro Foundation

Title: Reprogramming reactive astrocytes may improve cognitive outcomes after SAH
Principal Investigator: HuiMahn Alex Choi
Department/Division: Neurosurgery
Period of Support: 2/27/2024–2/26/2025
Total Direct Costs: $34,817.00

University of Houston

Title: Cortical Complications of Perimenopause and Obstructive Sleep Apnea in Underrepresented Middle-Aged Women with Type 2 Diabetes
Principal Investigator: Reeba Mathew
Department/Division: Internal Medicine, Pulmonary
Period of Support: 9/20/2023–9/19/2025
Total Direct Costs: $139,194.00

January

American Heart Association

Title: The Role of Fibroblasts in Cerebral Amyloid Angiopathy
Principal Investigator: Kiersten Anne Scott
Department/Division: Neurology
Period of Support: 1/1/2024–12/31/2025
Total Direct Costs: $67,388.00

Merck Sharp & Dohme Corp.

Title: The effect of SGLT2i ± MK-2947 treatment on the progression of heart failure
Principal Investigator: Emil Martin
Department/Division: Internal Medicine, Cardiology
Period of Support: 1/3/2024–1/2/2026
Total Direct Costs: $210,475.00

Brain & Behavior Research Foundation

Title: Low Intensity Focused Ultrasound of the Amygdala as a Potential Treatment for Depression with Anxious Distress
Principal Investigator: Andrea Boscutti
Department/Division: Psychiatry & Behavioral Science
Period of Support: 1/15/2024–1/14/2026
Total Direct Costs: $70,000.00

Iliad Biotechnologies, LLC

Title: The potential for intranasal pertussis toxin to initiate celiac disease pathology in mice
Principal Investigator: J Marc Rhoads
Department/Division: Pediatrics, Gastroenterology
Period of Support: 1/1/2024–12/31/2025
Total Direct Costs: $211,793.00

The University of Texas MD Anderson Cancer Center

Title: LC220272: Unbiased microfluidics-based isolation of antigen-specific T cells in non-small cell lung cancer
Principal Investigator: Pamela Lynn Wenzel
Department/Division: Integrative Biology and Pharmacology
Period of Support: 9/30/2023–9/29/2025
Total Direct Costs: $18,571.00

Neuroendocrine Tumor Research Foundation

Title: Harnessing ferroptosis initiating drugs to target GEP-NETs
Principal Investigator: Jeffrey A. Frost
Department/Division: Integrative Biology and Pharmacology
Period of Support: 1/4/2024–1/3/2026
Total Direct Costs: $245,456.00

Aotrauma North America

Title: Biomechanics Comparison of Compressive Staples Versus Locked Plating for Lisfranc Injury
Principal Investigator: Timothy S Achor
Department/Division: Orthopaedics Surgery
Period of Support: 7/1/2023–8/31/2024
Total Direct Costs: $10,000.00

Texas Department of State Health Services

Title: Newborn Screening Consultation Program
Principal Investigator: Hope Northrup
Department/Division: Pediatrics, Genetics
Period of Support: 1/8/2024–8/31/2028
Total Direct Costs: $125,000.00

Pediatric Orthopaedic Society of North America

Title: Posterior Spinal Fusion Models in Adolescent Idiopathic Scoliosis Patients
Principal Investigator: Shiraz Younas
Department/Division: Orthopaedics Surgery
Period of Support: 12/1/2023–11/30/2024
Total Direct Costs: $1,000.00

National Heart, Lung, & Blood Institute

Title: On the Basis of Sex: The Role of Sex chromosomal complement in Atrial Fibrillation and Dementia
Principal Investigator: Bharti Manwani
Department/Division: Neurology
Period of Support: 9/1/2023–8/31/2027
Total Direct Costs: $1,751,828.00

Episcopal Health Foundation

Title: HOPEful: Leveraging Pregnancy Medicaid Expansion through Home Outreach
Principal Investigator: Logan Rhea Thornton
Department/Division: UTP DSRIP Projects
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $373,822.00

Texas Alzheimer’s Research & Care Consortium

Title: TARCC Symposium 2024
Principal Investigator: Rodrigo Morales
Department/Division: Neurology
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $19,375.00

Research Triangle Institute

Title: The Darbepoetin Kindergarten Development Study
Principal Investigator: Ricardo Alberto Mosquera
Department/Division: Pediatrics, Pulmonary, Allergy, Immunology, Rhematology
Period of Support: 9/1/2023–8/31/2024
Total Direct Costs: $13,038.00

Baylor College of Medicine

Title: Exploring Pathways through which Structural Racism Impacts Children’s Environmental Health
Principal Investigator: Thomas Francis Northrup
Department/Division: Family Practice
Period of Support: 9/1/2023–5/31/2025
Total Direct Costs: $391,841.00

Methodist Hospital Research Institute

Title: Microbiota-targeted approaches to resolve dysbiosis-induced AD neuropathology following brain injury
Principal Investigator: Rodrigo Morales
Department/Division: Neurology
Period of Support: 9/15/2023–8/31/2024
Total Direct Costs: $65,183.00

National Institute of Diabetes & Digestive & Kidney Diseases

Title: Energizing good fat by neurovascular development
Principal Investigator: Xin Li
Department/Division: IMM, Metabolic Degenerative Diseases
Period of Support: 1/22/2024–12/31/2026
Total Direct Costs: $375,000.00

National Institutes of Health

Title: Structure and Function of Porphyromonas gingivalis Type IX Secretion System
Principal Investigator: Bo Hu
Department/Division: Microbiology and Molecular Genetics
Period of Support: 1/1/2024–12/31/2028
Total Direct Costs: $1,402,079.00

Technical University of Munich

Title: Releasing the full potential of DNA repair inhibition in prostate cancer
Principal Investigator: Ali Azhdarinia
Department/Division: IMM, Precision Biomedicine
Period of Support: 9/30/2022–9/29/2025
Total Direct Costs: $224,277.00

Episcopal Health Foundation

Title: To Strengthen Pediatric Provider Capacity to Support the ERH of their Families through their Clinic’s Reach Out and Read Program starting at the First Newborn Visit
Principal Investigator: Jocelyn M McConnell
Department/Division: Pediatrics, Childrens Learning Institute
Period of Support: 1/1/2024–12/31/2025
Total Direct Costs: $342,123.00

American Gastroenterological Association

Title: Role of Hypoxia-Inducible Factors in Hepatic Ischemia/Reperfusion Injury
Principal Investigator: Yankai Wen
Department/Division: Anesthesiology
Period of Support: 4/1/2024–3/31/2025
Total Direct Costs: $30,000.00

University of Maryland at Baltimore

Title: Lifespan Vascular Biology on White Matter
Principal Investigator: L. Elliot Hong
Department/Division: Psychiatry & Behavioral Science
Period of Support: 8/30/2023–8/29/2024
Total Direct Costs: $88,160.00

University of Alabama at Birmingham

Title: Coronary Artery Risk Development in Young Adults (CARDIA) Study – Coordinating Center
Principal Investigator: Myriam Fornage
Department/Division: IMM, Human Genetics
Period of Support: 7/1/2023–6/30/2024
Total Direct Costs: $70,600.00

St. David’s Foundation

Title: Reach Out and Read: Enhancing Pediatric Provider Supports in Central Texas (St. David’s Foundation)
Principal Investigator: Jocelyn M McConnell
Department/Division: Pediatrics, Childrens Learning Institute
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $43,478.00

December

American Heart Association

Title: BRAINS Summer Undergraduate Research Program
Principal Investigator: Louise D McCullough
Department/Division: Neurology
Period of Support: 1/1/2024–12/31/2026
Total Direct Costs: $245,265.00

National Institute of Mental Health/NIH/DHHS

Title: Corticothalamic circuits mediating behavioral adaptations to unexpected reward omission
Principal Investigator: Fabricio Hoffmann Monte
Department/Division: Neurobiology & Anatomy
Period of Support: 7/13/2023–4/30/2028
Total Direct Costs: $1,938,675.00

National Institute of General Medical Sciences/NIH/DHHS

Title: Medical Scientist Training Program
Principal Investigator: Dianna M. Milewicz
Department/Division: Internal Medicine, Medical Genetics
Period of Support: 8/23/2023–6/30/2028
Total Direct Costs: $2,492,650.00

National Institute of Neurological Disorders & Stroke/NIH/DHHS

Title: Gulf Regional Area Stroke Program and Oklahoma
Principal Investigator: Sean I Savitz
Department/Division: Neurology
Period of Support: 12/5/2023–11/30/2028
Total Direct Costs: $1,332,565.00

The John Ritter Foundation for Aortic Health

Title: John Ritter Research Program in Aortic and Vascular Disease
Principal Investigator: Dianna M. Milewicz
Department/Division: Internal Medicine, Medical Genetics
Period of Support: 9/30/2023–9/29/2024
Total Direct Costs: $100,000.00

The John Ritter Foundation for Aortic Health

Title: John Ritter ACTA2/SMDS research
Principal Investigator: Dianna M. Milewicz
Department/Division: Internal Medicine, Medical Genetics
Period of Support: 9/30/2023–9/29/2024
Total Direct Costs: $75,000.00

University of Maryland at Baltimore

Title: Kynurenic Acid and Cognitive Abnormalities in Schizophrenia
Principal Investigator: L. Elliot Hong
Department/Division: Psychiatry & Behavioral Science
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $55,624.00

Arthrex, Inc.

Title: Sports Medicine Fellowship Program AY 2023-2024
Principal Investigator: Steven Flores
Department/Division: Orthopaedic Surgery
Period of Support: 11/16/2023–11/15/2024
Total Direct Costs: $75,000.00

Emory University

Title: Molecular Regulation of B cells and T cells in Human SLE
Principal Investigator: J William Lindsey
Department/Division: Neurology
Period of Support: 5/1/2023–4/30/2024
Total Direct Costs: $264,160.00

University of Iowa

Title: Brazil quality improvement project at Sao Lucas Hospital in Lucas do Rio Verde, Brazil
Principal Investigator: Mary Becker Rysavy
Department/Division: Obstetrics, Gynecology, & Reproductive Sciences
Period of Support: 7/1/2023–3/31/2024
Total Direct Costs: $24,116.00

University of Iowa

Title: HPV vaccine quality improvement project in Uganda
Principal Investigator: Mary Becker Rysavy
Department/Division: Obstetrics, Gynecology, & Reproductive Sciences
Period of Support: 8/1/2023–7/31/2024
Total Direct Costs: $24,116.00

The Children’s Hospital of Philadelphia Research Institute

Title: Chronic Kidney Disease in Children
Principal Investigator: Joshua Samuels
Department/Division: Pediatrics, Administration
Period of Support: 9/15/2023–7/31/2028
Total Direct Costs: $46,144.00

University of Virginia

Title: AERO ELs: Supporting K-3 Educators to Deliver a Technology-Based Reading Intervention for EL Students at Risk for LDs
Principal Investigator: Michael Peter Mesa
Department/Division: Pediatrics, Children’s Learning Institute
Period of Support: 10/1/2023–9/30/2028
Total Direct Costs: $736,441.00

National Institute of Neurological Disorders & Stroke/NIH/DHHS

Title: Modulation of CSF1R Signaling to Treat Inflammatory Neuropathies
Principal Investigator: Kazim A Sheikh
Department/Division: Neurology
Period of Support: 12/15/2023–11/30/2028
Total Direct Costs: $1,824,146.00

The Research Foundation for the State University of New York

Title: Pediatric Emergency Care Applied Research Network / The Charlotte, Houston, And Milwaukee Prehospital Research Node
Principal Investigator: Kevin J Schulz
Department/Division: Emergency Medical Services
Period of Support: 9/1/2023–8/31/2027
Total Direct Costs: $31,052.00

Huntington Study Group

Title: Open label rollover study for continuing valbenazine administration for the treatment of chorea associated with Huntington disease
Principal Investigator: Erin Furr Stimming
Department/Division: Neurology
Period of Support: 12/11/2023–12/10/2028
Total Direct Costs: $6,741.00

National Institute of Diabetes & Digestive & Kidney Diseases/NIH/DHHS

Title: Neural pathways for obesity development by AgRP neurons
Principal Investigator: Qingchun Tong
Department/Division: IMM, Metabolic Degenerative Diseases
Period of Support: 4/19/2023–3/31/2027
Total Direct Costs: $1,155,076.00

BioGaia

Title: The effect of the combination of probiotic and HMO in immune development of newborn mice
Principal Investigator: J Marc Rhoads
Department/Division: Pediatrics, Gastroenterology
Period of Support: 11/1/2023–12/31/2025
Total Direct Costs: $233,333.00

Ultragenyx Pharmaceutical Inc

Title: Proof-of-concept pharmacology study with UX045 ASO in PSACH mice
Principal Investigator: Karen Posey
Department/Division: Pediatrics, Research Center
Period of Support: 12/11/2023–12/10/2024
Total Direct Costs: $79,487.00

W.L. Gore & Associates, Inc.

Title: IMPROVE-AD: IMPRoving Outcomes in Vascular DisEase – Aortic Dissection
Principal Investigator: Firas F. Mussa
Department/Division: Cardiothoracic & Vascular Surgery
Period of Support: 12/13/2023–12/12/2030
Total Direct Costs: $1,538,462.00

Methodist Hospital Research Institute

Title: MRI characterization of tibial occlusions to predict safety of guidewires with histologic validation
Principal Investigator: L Maximilian Buja
Department/Division: Pathology and Laboratory Medicine
Period of Support: 7/1/2023–6/30/2024
Total Direct Costs: $4,970.00

University of Texas Foundation, Inc.

Title: UTHealth Houston Stroke Institute Educational Outreach Program
Principal Investigator: Elizabeth Noser
Department/Division: Neurology
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $35,624.00

National Institutes of Health/DHHS

Title: Macrophage NUDT21-mediated alternative polyadenylation in lung injury
Principal Investigator: Tingting W Mills
Department/Division: Biochemistry Molecular Biology
Period of Support: 12/15/2023–12/14/2027
Total Direct Costs: $1,376,981.00

Burroughs Wellcome Fund

Title: FEBS Advanced Lecture Course on molecular mechanisms of host-pathogen interactions and virulence in human fungal pathogens
Principal Investigator: Michael Lorenz
Department/Division: Microbiology and Molecular Genetics
Period of Support: 2/1/2024–5/31/2024
Total Direct Costs: $5,000.00

Huntington’s Disease Society of America

Title: Home-based TDCS for cognitive and behavioral symptoms in Huntington’s disease: a pilot feasibility and mechanistic study
Principal Investigator: Thiago Macedo e Cordeiro
Department/Division: Psychiatry & Behavioral Science
Period of Support: 11/1/2023–10/31/2025
Total Direct Costs: $149,138.00

Yale University

Title: Deciphering the single-nucleus genomic regulatory structure of opioid use disorder in the human brain
Principal Investigator: Consuelo Walss-Bass
Department/Division: Psychiatry & Behavioral Science
Period of Support: 7/1/2023–5/31/2028
Total Direct Costs: $123,570.00

American Academy of Neurology

Title: Stroke Translation Assessment Tool (STAT), a Tool for Treating Patients with Limited English Proficiency
Principal Investigator: Ivan Trang
Department/Division: Neurology
Period of Support: 1/1/2024–12/31/2024
Total Direct Costs: $4,715.00

Emory University

Title: Cardiac Arrest Registry to Enhance Survival (CARES) Expansion and Modernization.
Principal Investigator: Bentley Jordan Bobrow
Department/Division: Emergency Medical Services
Period of Support: 9/30/2023–9/29/2028
Total Direct Costs: $1,849,940.00

Joint Admission Medical Program

Title: Joint Admissions Medical Program FY 2024
Principal Investigator: Rachel Jantea
Department/Division: McGovern Medical School Admissions
Period of Support: 9/1/2023–8/31/2024
Total Direct Costs: $186,365.00

November

Zoll Medical Corporation

Title: Traumatic Brain Injury (TBI)/Cardiopulmonary Resuscitation (CPR) University
Principal Investigator: Bentley Jordan Bobrow
Department/Division: Emergency Medical Services
Period of Support: 9/1/2023–8/31/2024
Total Direct Costs: $48,800.00

Huntington’s Disease Society of America

Title: Olfactory dysfunction as a proxy of HD progression
Principal Investigator: Natalia Pessoa Rocha
Department/Division: Neurology
Period of Support: 12/1/2023–11/30/2025
Total Direct Costs: $150,000.00

Edwards Lifesciences, LLC

Title: Interventional and Structural Heart Cardiology Fellowship Grant 2023-2024
Principal Investigator: Salman A Arain
Department/Division: Internal Medicine, Cardiology
Period of Support: 7/1/2023–6/30/2024
Total Direct Costs: $100,000.00

Methodist Hospital Research Institute

Title: Service Agreement for Dr. Dragoi Laboratory Services
Principal Investigator: Pramod Dash
Department/Division: Neurobiology & Anatomy
Period of Support: 9/16/2023–4/30/2024
Total Direct Costs: $779,675.00

University of Southern California

Title: Epidemiological and Biostatistical Assistance for Project 1.2b: Techa River Population Cancer Morbidity and Mortality and Project 2.2: Mayak Worker Cancer Mortality
Principal Investigator: Deukwoo Kwon
Department/Division: Internal Medicine
Period of Support: 4/17/2023–4/16/2024
Total Direct Costs: $48,077.00

Methodist Hospital Research Institute

Title: A randomized sham-controlled clinical trial evaluating individualized neurostimulation of cortical regions involved in neurogenic bladder in Multiple Sclerosis
Principal Investigator: John A Lincoln
Department/Division: Neurology
Period of Support: 1/24/2023–12/31/2027
Total Direct Costs: $120,249.00

Medical Device Business Services, Inc.

Title: AO Trauma NA Blended Course – Advanced Principles of Fracture Management
Principal Investigator: William C. McGarvey
Department/Division: Orthopaedic Surgery
Period of Support: 11/13/2023–10/5/2024
Total Direct Costs: $5,000.00

The Henderson-Wessendorff Foundation

Title: Expanding the Reach of Evidence-Based Early Childhood Services
Principal Investigator: Funlola Ganiat Are
Department/Division: Psychiatry & Behavioral Science
Period of Support: 9/1/2023–12/31/2024
Total Direct Costs: $203,525.00

Houston Galveston Area Council

Title: Early Education Quality
Principal Investigator: April Crawford
Department/Division: Pediatrics, Children’s Learning Institute
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $10,000,000.00

Barbara Bush Houston Literacy Foundation

Title: Reach Out and Read in Metro Houston Pediatric Clinics
Principal Investigator: Jocelyn M McConnell
Department/Division: Pediatrics, Children’s Learning Institute
Period of Support: 9/27/2023–6/30/2024
Total Direct Costs: $13,889.00

MD Anderson Cancer Center

Title: Targeting the A2B Adenosine Receptor for Immunoprevention of Pancreatic Cancer
Principal Investigator: Jennifer M Lundberg
Department/Division: Anesthesiology
Period of Support: 9/15/2023–3/14/2025
Total Direct Costs: $159,007.00

Alzheimer’s Association

Title: The therapeutic effect of plasma exchange in Amyloid beta (Aß) pathology.
Principal Investigator: Suelyn Koerich
Department/Division: Neurology
Period of Support: 12/1/2023–11/30/2026
Total Direct Costs: $183,635.00

Boston University

Title: Precursors of Stroke Incidence and Prognosis
Principal Investigator: Myriam Fornage
Department/Division: IMM, Human Genetics
Period of Support: 9/9/2023–8/31/2028
Total Direct Costs: $50,827.00

October

University of California San Francisco

Title: Peri-ictal respiratory and arousal disturbances in focal epilepsy: Role of the brainstem
Principal Investigator: Samden Lhatoo
Department/Division: Neurology
Period of Support: 6/15/2023–6/14/2024
Total Direct Costs: $24,888.00

Emory University

Title: Sialoglycoproteomic network and target discovery for Alzheimer’s disease
Principal Investigator: Sheng Pan
Department/Division: IMM, Precision Biomedicine
Period of Support: 8/15/2023–6/30/2028
Total Direct Costs: $102,564.00

Baylor College of Medicine

Title: Astrocyte regulation of amygdala circuit function
Principal Investigator: Consuelo Walss-Bass
Department/Division: Psychiatry & Behavioral Science
Period of Support: 9/1/2023–7/31/2025
Total Direct Costs: $39,998.00

Duke University

Title: 1/2 IMPRoving Outcomes in Vascular DisEase – Aortic Dissection (IMPROVE-AD) Clinical Coordinating Center
Principal Investigator: Firas F. Mussa
Department/Division: Cardiothoracic & Vascular Surgery
Period of Support: 7/1/2023–6/30/2030
Total Direct Costs: $110,453.00

Latinos for Education, Inc.

Title: Latinos for Education Program Research Consultant
Principal Investigator: Keisey Glenna Fumero
Department/Division: Pediatrics, Children’s Learning Institute
Period of Support: 8/24/2023–9/15/2024
Total Direct Costs: $14,784.00

MeMed Diagnostics, Ltd.

Title: Diagnostic test utilizing assays to differentiate between viral and bacterial infections in humans based on immune system proteins
Principal Investigator: David J. Robinson
Department/Division: Emergency Medical Services
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $56,996.00

American Psychological Association

Title: Supporting Teachers in Making Data-Driven Decisions about Small-Group Composition
Principal Investigator: Michael Peter Mesa
Department/Division: Pediatrics, Children’s Learning Institute
Period of Support: 8/1/2023–7/31/2024
Total Direct Costs: $6,000.00

American Orthopaedic Foot and Ankle Society

Title: Foot & Ankle Fellowship FY23-24
Principal Investigator: William C. McGarvey
Department/Division: Orthopaedics Surgery
Period of Support: 8/1/2023–7/31/2024
Total Direct Costs: $20,000.00

Ohio State University

Title: ENIGMA-COINSTAC: Advanced worldwide transdiagnostic analysis of valence system brain circuit
Principal Investigator: Peter Kochunov
Department/Division: Psychiatry & Behavioral Science
Period of Support: 8/1/2023–5/31/2024
Total Direct Costs: $57,693.00

Texas Department of Family & Protective Services

Title: Building Capacity to Improve Texas Adult Protective Services Financial Exploitation Investigations and Client Services
Principal Investigator: Jason Burnett
Department/Division: Internal Medicine, Geriatrics
Period of Support: 9/1/2023–8/31/2024
Total Direct Costs: $177,983.00

Weill Medical College of Cornell University

Title: 1/2 Doxycycline for Emphysema in People Living with HIV: The DEPTH Trial
Principal Investigator: Jordan Elizabeth Lake
Department/Division: Internal Medicine, Infectious
Period of Support: 9/1/2022–8/31/2024
Total Direct Costs: $3,979.00

University of California San Diego

Title: Validation of a pediatric thrombosis risk assessment model and characterization of bleeding in hospitalized children through the Children’s Hospital Acquired Thrombosis (CHAT) consortium 7 K23 HL18333
Principal Investigator: Lakshmi Venkat Srivaths
Department/Division: Pediatrics, Gulf States Hemophilia Center
Period of Support: 8/1/2023–7/31/2027
Total Direct Costs: $1,111.00

Michael E. Debakey Veterans Affairs Medical Center/VA

Title: Anatomic Microniches and Their Contribution to Vascular Remodeling in Pulmonary Hypertension
Principal Investigator: Harry Karmouty-Quintana
Department/Division: Biochemistry Molecular Biology
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $3,878.00

Michael E. Debakey Veterans Affairs Medical Center/VA

Title: Anatomic Microniches and Their Contribution to Vascular Remodeling in Pulmonary Hypertension
Principal Investigator: Andrew Milton Peters
Department/Division: Biochemistry Molecular Biology
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $37,552.00

September

National Institute of Child Health & Human Development/NIH/DHHS

Title: Mechanistic investigation into Frizzled-2 signaling for treatment of Osteogenesis Imperfecta
Principal Investigator: Mary I. Adeyeye
Department/Division: Pediatrics, Research Center
Period of Support: 9/1/2023–8/31/2026
Total Direct Costs: $143,082.00

National Institute on Aging/NIH/DHHS

Title: Circadian Pathways Linking Metabolic Homeostasis and Gene Regulation During Aging
Principal Investigator: Zheng Chen
Department/Division: Biochemistry Molecular Biology
Period of Support: 9/15/2023–8/31/2024
Total Direct Costs: $248,013.00

Animal & Plant Health Inspection Service/USDA

Title: Feral swine as spreaders of Chronic Wasting Disease prions
Principal Investigator: Rodrigo Morales
Department/Division: Neurology
Period of Support: 9/30/2023–9/29/2024
Total Direct Costs: $230,908.00

Animal & Plant Health Inspection Service/USDA

Title: Identification and characterization of CWD contaminated meats
Principal Investigator: Rodrigo Morales
Department/Division: Neurology
Period of Support: 9/30/2023–9/29/2024
Total Direct Costs: $231,028.00

Novo Nordisk A/S

Title: A Randomized Controlled Trial of Once-Weekly Semaglutide for Limiting Post-Smoking Cessation Weight Gain in Adult Smokers with Overweight/Obesity
Principal Investigator: Luba Yammine
Department/Division: Psychiatry & Behavioral Science
Period of Support: 9/11/2023–9/10/2026
Total Direct Costs: $719,131.00

Houston Regional HIV/AIDS Resource Group, Inc.

Title: Ryan White Part D
Principal Investigator: Norma Perez
Department/Division: Pediatrics, Infectious Disease
Period of Support: 8/1/2023–7/31/2024
Total Direct Costs: $179,525.00

Abiomed, Inc.

Title: Educational Grant Support for 2023 Brano Heart Failure Forum
Principal Investigator: Igor D. Gregoric
Department/Division: ACTAT
Period of Support: 9/13/2023–9/15/2023
Total Direct Costs: $40,000.00

Baylor College of Medicine

Title: Single Cell Analysis of Epigenetic Mechanisms that Regulate HIV-1 CNS Latency and Neuropathogenesis
Principal Investigator: Consuelo Walss-Bass
Department/Division: Psychiatry & Behavioral Science
Period of Support: 7/6/2023–4/30/2028
Total Direct Costs: $477,705.00

US Army Medical Research Acquisition Activity/DOD

Title: Detection and characterization of alpha-synuclein aggregates in patients with Alzheimer’s disease and related dementia
Principal Investigator: Mohammad Shahnawaz
Department/Division: Neurology
Period of Support: 9/15/2023–9/14/2026
Total Direct Costs: $175,723.00

US Department of Defense

Title: Trauma induced coagulopathy and the blood brain barrier: Impact of resuscitation
Principal Investigator: Charles S Cox Jr
Department/Division: Pediatric Surgery
Period of Support: 9/15/2023–9/14/2027
Total Direct Costs: $4,999,999.00

National Institute of Neurological Disorders and Stroke/NIH/DHHS

Title: Neural Recording and Simulation Tools to Address the Mesoscale Gap
Principal Investigator: John P. Seymour
Department/Division: Neurosurgery
Period of Support: 9/19/2023–8/31/2026
Total Direct Costs: $3,960,846.00

American Association for Cancer Research

Title: Role of RET in Mediating Brain Metastasis of Triple-Negative Breast Cancer
Principal Investigator: Angelina T. Regua
Department/Division: Neurosurgery
Period of Support: 9/1/2023–8/31/2025
Total Direct Costs: $206,000.00

National Institute on Aging/NIH/DHHS

Title: Contribution of HUWE1 to sex differences in aging and Alzheimer’s disease
Principal Investigator: Andrey Tsvetkov
Department/Division: Neurology
Period of Support: 9/22/2023–5/31/2025
Total Direct Costs: $334,864.00

Massachusetts General Hospital

Title: Preventing Graft Thrombosis in the Elderly through Development of a Risk Prediction Tool
Principal Investigator: Jessica C Cardenas
Department/Division: Center for Translational Injury Research
Period of Support: 6/1/2023–5/31/2024
Total Direct Costs: $23,518.00

Bipolar Discoveries

Title: BD2 Integrated Network
Principal Investigator: Jair C Soares
Department/Division: Psychiatry & Behavioral Science
Period of Support: 7/1/2023–6/30/2028
Total Direct Costs: $1,999,999.00

National Cancer Institute/NIH/DHHS

Title: Enhanced Viro-Immunotherapy for Breast Cancer Brain Metastasis
Principal Investigator: Ji Young Yoo
Department/Division: Neurosurgery
Period of Support: 9/22/2023–8/31/2028
Total Direct Costs: $1,603,125.00

Genprex

Title: Efficacy of REQORSA(R) (quaratusugene ozeplasmid) in Glioblastoma
Principal Investigator: Hui-Wen Lo
Department/Division: Neurosurgery
Period of Support: 12/1/2023–9/23/2024
Total Direct Costs: $41,468.00

Case Western Reserve University

Title: Using mHealth to improve adherence and reduce blood pressure in individuals with hypertension and bipolar disorder
Principal Investigator: Rodrigo Machado Vieira
Department/Division: Psychiatry & Behavioral Science
Period of Support: 10/1/2022–4/30/2024
Total Direct Costs: $40,892.00

Joint Admission Medical Program

Title: Joint Admissions Medical Program (JAMP) FY 2024
Principal Investigator: Rachel Jantea
Department/Division: MS Admissions
Period of Support: 9/1/2023–8/31/2024
Total Direct Costs: $186,365.00

Office of the Governor

Title: Serving Domestic Violence Survivors with Evidence-Based, Best Practices Psychotherapy Services
Principal Investigator: Ronald Ettore Acierno
Department/Division: Psychiatry & Behavioral Science
Period of Support: 10/1/2023–9/30/2024
Total Direct Costs: $169,578.00

Yale University

Title: Hematopoietic Stem Cell Transplantation for Young Adults with Sickle Cell Disease
Principal Investigator: Binsah Susan George
Department/Division: Internal Medicine, Hematology
Period of Support: 11/1/2022–10/31/2023
Total Direct Costs: $2,673.00

University of Southern California

Title: Pilot study of linezolid for early syphilis treatment
Principal Investigator: Diane G. Edmondson
Department/Division: Pathology And Laboratory Medicine
Period of Support: 11/22/2022–11/21/2024
Total Direct Costs: $55,618.00

Harris County Public Health

Title: Ryan White Title 1 Formula (DHHS) Output Ambulatory Grants (TS) 2023-2024
Principal Investigator: David D. McPherson
Department/Division: Internal Medicine, Cardiology
Period of Support: 3/1/2023–2/29/2024
Total Direct Costs: $490,172.00

US Department of Defense

Title: Autologous Adipose Derived MSCs for Chronic Traumatic Brain Injury
Principal Investigator: Charles S Cox Jr
Department/Division: Pediatric Surgery
Period of Support: 9/30/2023–9/29/2027
Total Direct Costs: $3,915,209.00