Areas of Interest

Research Interests

• The DNA methylation canyon (Nature Genetics 2014, Molecular Cell 2020) spatial interaction and its function in hematopoietic stem cell maintenance and leukemia development.

• Transcription condensate dys-regulation in the leukemic gene expression regulation in of NPM1 mutated leukemia.

• 3D genomic organization in development and disease, biomolecular condensate in transcription regulation in development and disease,
gene expression regulation in normal hematopoiesis and leukemia