• The DNA methylation canyon (Nature Genetics 2014, Molecular Cell 2020) spatial interaction and its function in hematopoietic stem cell maintenance and leukemia development.
• Transcription condensate dys-regulation in the leukemic gene expression regulation in of NPM1 mutated leukemia.
• 3D genomic organization in development and disease, biomolecular condensate in transcription regulation in development and disease,
gene expression regulation in normal hematopoiesis and leukemia
Biological Sciences, Fudan University
Molecular Human Genetics, Baylor College of Medicine
Van Andel Research Institute
Genetics and Epigenetics
Cancer Biology