Targeting enzyme could alleviate muscle wasting for cancer patients

December 8, 2022

By Caitie Barkley, Office of Public Affairs
December 8, 2022

Targeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially prolong their survival, according to research from UTHealth Houston.

A study led by Yi-Ping Li, PhD, professor in the Department of Integrative Biology and Pharmacology, found that an enzyme known as UBR2 plays a critical role in cancer-induced muscle wasting, also called cancer cachexia.

The results are published in the scientific journal PNAS.


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