2. Li Laboratory
  3. Selected Publications

Selected Publications

Year 2021:

  • Wang R *, Lee J-H *, Xiong F, Kim J, Al Hasani L, Krakowiak J, Yuan X, et al. Eltzschig KH, Li W#. SARS-CoV-2 Restructures the Host Chromatin Architecture. bioRxiv. 2021 Jul 21. doi: 10.1101/2021.07.20.453146. PubMed PMID: 34312624; PubMed Central PMCID: PMC8312896. [Pre-print] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312896/ (external link)
  • Lee J-H *, Wang R *, Xiong F *, Krakowiak J, Liao Z, Nguyen P T, et al. Li W#. Enhancer RNA Methylation Orchestrates Transcriptional Condensate Formation and Gene Activation. Molecular Cell. (2021). 81(16):3368-3385.e9. doi: 10.1016/j.molcel.2021.07.024. PubMed PMID: 34375583. https://pubmed.ncbi.nlm.nih.gov/34375583/ (external link)
  • Oh S, Shao J *, Mitra J *, Xiong F, et al. Li W#, Rosenfeld MG#. “Enhancer Release and Retargeting” Activates Disease Susceptibility Genes. Nature. (2021). 595(7869):735-740. doi: 10.1038/s41586-021-03577-1. PubMed PMID: 34040254. https://pubmed.ncbi.nlm.nih.gov/34040254/ (external link)
  • Xiong F *, Wang R *, Lee J-H, Li S, Chen S-F, Liao Z, Nguyen P T, Zhu X, Krakowiak J, Tsai K-L, Liu Y, Li W#. RNA m6A Modification Orchestrates a LINE-1/Host Interaction That Facilitates Retrotransposition and Contributes to Long Gene Vulnerability. Cell Research. (2021) 8:861-885. doi: 10.1038/s41422-021-00515-8. PubMed PMID: 34108665. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324889/ (external link)
  • Hanmandlu A, Zhu L, Mertens TC, Collum S, Bi W, Xiong F, Wang R, Amirthalingam RT, Ren D, Han L, Jyothula SS, Li W, Zheng WJ, Karmouty-Quintana H. Transcriptomic and Epigenetic Profiling of Fibroblasts in Idiopathic Pulmonary Fibrosis (IPF). Am J Respir Cell Mol Biol. (2021). doi: 10.1165/rcmb.2020-0437OC. PubMed PMID: 34370624. https://pubmed.ncbi.nlm.nih.gov/34370624/ (external link)
  • Zhang Z, Hong W, Ruan H, Jing Y, Li S, Liu Y, Wang J, Li W, Diao L, Han L. HeRA: an atlas of enhancer RNAs across human tissues.  doi: 10.1093/nar/gkaa940. PubMed PMID: 33119754; Nucleic Acids Res. (2021). 49(D1):D932-D938. doi: 10.1093/nar/gkaa940. PubMed PMID: 33119754. https://pubmed.ncbi.nlm.nih.gov/33119754/ (external link)

Year 2020:

  • Lin C, Li W. Noncoding RNAs as regulators of cancer. doi: 10.1080/15476286.2020.1813920. RNA Biol. (2020) [Editorial]. https://pubmed.ncbi.nlm.nih.gov/32892700/ (external link)
  • Yang M, Lee JH, Zhang Z, De La Rosa R, Bi M, Tan Y, Liao Y, Hong J, Du B, Wu Y, Scheirer J, Hong T, Li W, Fei T, Hsieh CL, Liu Z, Li W, Rosenfeld MG, Xu K. Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor.  Cell Rep. (2020). doi: 10.1016/j.celrep.2020.107803. https://pubmed.ncbi.nlm.nih.gov/32579929/ (external link)
  • González-Rodríguez P, Cheray M, Füllgrabe J, Salli M, Engskog-Vlachos M, Keane L, Cunha V, Agata Lupa A, Li W, Ma Q, Dreij K, Rosenfeld MG, Joseph B. The DNA methyltransferase DNMT3A contributes to autophagy long-term memory. Autophagy. (2020). https://europepmc.org/article/pmc/pmc8143216 (external link)
  • Liao Z*, Lee J-H*, Krakowiak J, Wang R, Li W#. Enforced Activation of Enhancer RNAs In Situ through the dCas9 Synergistic Activation Mediator System. J Vis Exp. PMID: 32568241. (2020). https://pubmed.ncbi.nlm.nih.gov/32568241/ (external link)
  • Nguyen T; Kabotyanski E; Reineke L; Shao J; Xiong F; Lee J-H; Dubrulle J; Johnson H; Stossi F; Tsoi, P; Choi K-J; Ellis A; Zhao N; Cao J; Adewunmi O; Ferreon J; Ferreon A; Neilson J; Mancini M; Chen X; Kim J; Ma L; Li W; Rosen M. Jeff. The SINEB1 Element in the Long Non-coding RNA Malat1 is Necessary for TDP-43 Proteostasis. Nucleic Acids Research. (2020). https://pubmed.ncbi.nlm.nih.gov/31863590/ (external link)
  • Lee J-H*, Xiong F*, Li W#. Enhancer RNAs in Cancer: regulation, mechanisms and therapeutic potential. RNA Biology, (2020). [Review] https://pubmed.ncbi.nlm.nih.gov/31916476/ (external link)

Years 2018 and 2019:

Years 2017 and 2016: