Welcome to the Center for Membrane Biology (CMB) at the University of Texas Medical School.

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The CMB, housed in the Department of Biochemistry & Molecular Biology, with participation also of the Departments of Integrative Biology & Pharmacology, and Microbiology & Molecular Genetics, provides a highly interactive environment with outstanding investigators with complementary research strengths.

CMB is dedicated to advancing our understanding of the structure, function, evolution, and roles of biological membranes in cells and organelles. It is our mission to conduct membrane research, basic and translational, on the cutting edge, stimulate and coordinate graduate education in membrane biology, and foster career development of membrane scientists in a world-class center of research excellence.

Faculty Members

  • John Spudich, Ph.D., Center Director
    Structure and function of photoactive membrane receptors and signal transduction triggered by light; rhodopsins and related heptahelical receptors.
  • Peter Christie, Ph.D.
    Macromolecular transport across prokaryotic and eukaryotic membranes; bacterial pathogenicity.
  • Carmen Dessauer, Ph.D.
    G protein mediated signal transduction; regulation of adenylyl cyclase and production of cyclic AMP; regulators of G protein signaling (RGS proteins); relaxin.
  • William Dowhan, Ph.D.
    Structure, function and assembly of cell membranes; lipid-assisted protein folding.
  • Alemayehu Gorfe, Ph.D.
    Use of computer simulations to study the organization of cell signaling components, interfacial interactions and allostery to aid in the development of treatments for unsolved health challenges
  • John Hancock, M.B., B.Chair, Ph.D.
    Plasma membrane nanostructure and signal transduction
  • Vasanthi Jayaraman, Ph.D.
    Structure and function of ligand gated ion channels; spectroscopic investigations of membrane proteins.
  • Ilya Levental, Ph.D.
    Membrane structure and post-translational lipidation
  • John Putkey, Ph.D.
    Structural and molecular biology of calcium-signaling mechanisms including cardiac muscle contraction, Ca2+ channels, and calmodulin and regulators of calmodulin signaling.
  • Irina Serysheva, Ph.D.
    Structure and function of integral membrane protein complexes; structural basis of ion transport across cell  membranes; calcium channels.
  • Lei Zheng, Ph.D.
    Structural biology of membrane proteins; ion transport and regulation; X-ray Crystallography.

Research Faculty

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