2. Gene Ontology Comparison Results

Gene Ontology Comparison Results

Description of the problem:
Number of classes: 2
Number of genes: 6799
Number of genes that passed filtering criteria: 6799
Number of investigated GO categories: 1231
Random variance model was not used because distribution assumptions of this model were not satisfied

GO categories which discriminate among classes:

Table – Sorted by p-value of the LS permutation test.
The first 15 GO categories are significant at the nominal 0.01 level of the LS permutation test or KS permutation test

GO category GO description Number of genes LS Permutation p-value KS Permutation p-value
1 0019992 diacylglycerol binding 11 0.00095 0.00018
2 0030532 small nuclear ribonucleoprotein complex 6 0.00111 0.0099
3 0016208 AMP binding 6 0.00496 0.12196
4 0015300 solute\:solute antiporter activity 6 0.00515 0.05095
5 0009072 aromatic amino acid family metabolism 7 0.00621 0.4628
6 0046148 pigment biosynthesis 7 0.00651 0.34548
7 0000160 two-component signal transduction system (phosphorelay) 5 0.00953 0.15316
8 0016779 nucleotidyltransferase activity 42 0.02063 0.00723
9 0051325 interphase 43 0.0393 0.00019
10 0051329 interphase of mitotic cell cycle 43 0.0393 0.00019
11 0000080 G1 phase of mitotic cell cycle 9 0.04143 0.00563
12 0051318 G1 phase 9 0.04143 0.00563
13 0019199 transmembrane receptor protein kinase activity 31 0.06295 0.00289
14 0000082 G1/S transition of mitotic cell cycle 29 0.08562 0.00556
15 0030934 anchoring collagen 5 0.14383 0.00528

Table Significant GO categories consist of the following genes:

GO category GO description Description Qiagen ID GB acc UG cluster Gene symbol Geometric mean of ratios ( Disease / Normal ) p-value
1 0019992 diacylglycerol binding V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) 1.243 0.33932
2 0019992 diacylglycerol binding Rho/rac guanine nucleotide exchange factor (GEF) 2 H003985_01 AB014551 (external link) 155120 ARHGEF2 (external link) 1.355 0.10846
3 0019992 diacylglycerol binding Protein kinase D2 H005622_01 AF151021 (external link) 91146 PKD2 (external link) 0.803 0.46456
4 0019992 diacylglycerol binding Ras association (RalGDS/AF-6) domain family 1 H008796_01 AF061836 (external link) 26931 RASSF1 (external link) 1.706 0.07124
5 0019992 diacylglycerol binding Chimerin (chimaerin) 1 H011078_01 X51408 (external link) 169965 CHN1 (external link) 2.371 0.00707
6 0019992 diacylglycerol binding Cholinephosphotransferase 1 H014496_01 NM_020244 (external link) 171889 LOC56994 (external link) 0.734 0.14947
7 0019992 diacylglycerol binding Rho-associated, coiled-coil containing protein kinase 2 H001360_01 NM_004850 (external link) 58617 ROCK2 (external link) 0.841 0.22988
8 0019992 diacylglycerol binding Protein kinase C, gamma H001596_01 Z15114 (external link) 2890 PRKCG (external link) 1.216 0.31059
9 0019992 diacylglycerol binding Diacylglycerol kinase, alpha (80kD) H001620_01 X62535 (external link) 172690 DGKA (external link) 0.721 0.27692
10 0019992 diacylglycerol binding Protein kinase C, iota H001676_01 L33881 (external link) 1904 PRKCI (external link) 0.627 0.09671
11 0019992 diacylglycerol binding Diacylglycerol kinase, zeta (104kD) H001680_01 U94905 (external link) 89981 DGKZ (external link) 0.633 0.12362
12 0030532 small nuclear ribonucleoprotein complex DKFZP434D174 protein H006736_01 AL080150 (external link) 302421 DKFZP434D174 (external link) 0.646 0.01071
13 0030532 small nuclear ribonucleoprotein complex U6 snRNA-associated Sm-like protein H006779_01 NM_012321 (external link) 76719 LSM4 (external link) 1.217 0.34087
14 0030532 small nuclear ribonucleoprotein complex Small nuclear ribonucleoprotein polypeptide A' H007604_01 X13482 (external link) 80506 SNRPA1 (external link) 0.764 0.08756
15 0030532 small nuclear ribonucleoprotein complex Gemin4 H008741_01 AF173856 (external link) 19614 GEMIN4 (external link) 0.505 0.02841
16 0030532 small nuclear ribonucleoprotein complex U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p H009322_01 AB007510 (external link) 181368 PRP8 (external link) 0.961 0.74755
17 0030532 small nuclear ribonucleoprotein complex Nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs) H009404_01 AJ276003 (external link) 69851 NOLA1 (external link) 0.551 0.02424
18 0016208 AMP binding Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 (external link) 183037 PRKAR1A (external link) 1.244 0.00681
19 0016208 AMP binding Rap1 guanine-nucleotide-exchange factor directly activated by cAMP H008675_01 U78168 (external link) 8578 EPAC (external link) 1.035 0.81688
20 0016208 AMP binding Cyclic nucleotide gated channel beta 1 H009827_01 AF042498 (external link) 93909 CNGB1 (external link) 0.885 0.16333
21 0016208 AMP binding Acetyl-CoA synthetase H009930_01 AK000188 (external link) 14779 LOC55902 (external link) 0.554 0.01774
22 0016208 AMP binding Hyperpolarization activated cyclic nucleotide-gated potassium channel 2 H010769_01 AJ012582 (external link) 124161 HCN2 (external link) 1.202 0.44732
23 0016208 AMP binding KIAA1535 protein H015256_01 AB040968 (external link) 284171 KIAA1535 (external link) 1.282 0.29396
24 0015300 solute\:solute antiporter activity Solute carrier family 22 (organic cation transporter), member 1-like H001870_01 AF030302 (external link) 50868 SLC22A1L (external link) 0.783 0.37607
25 0015300 solute\:solute antiporter activity Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 H004295_01 AB026891 (external link) 6682 SLC7A11 (external link) 1.331 0.00413
26 0015300 solute\:solute antiporter activity Solute carrier family 9 (sodium/hydrogen exchanger), isoform 5 H006240_01 AF111173 (external link) 198295 SLC9A5 (external link) 1.356 0.31776
27 0015300 solute\:solute antiporter activity Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 H006923_01 J03592 (external link) 164280 SLC25A6 (external link) 0.969 0.84669
28 0015300 solute\:solute antiporter activity Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 H008432_01 AF070548 (external link) 184877 SLC25A11 (external link) 1.17 0.36497
29 0015300 solute\:solute antiporter activity Solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride H001053_01 S68616 (external link) 170222 SLC9A1 (external link) 1.615 0.01454
30 0009072 aromatic amino acid family metabolism Tyrosine hydroxylase H002673_01 M17589 (external link) 178237 TH (external link) 1.055 0.8706
31 0009072 aromatic amino acid family metabolism Tyrosinase (oculocutaneous albinism IA) H003362_01 M27160 (external link) 2053 TYR (external link) 3.308 1e-04
32 0009072 aromatic amino acid family metabolism Silver (mouse homolog) like H003494_01 M77348 (external link) 95972 SILV (external link) 0.864 0.67214
33 0009072 aromatic amino acid family metabolism Kynureninase (L-kynurenine hydrolase) H005832_01 U57721 (external link) 169139 KYNU (external link) 0.771 0.36427
34 0009072 aromatic amino acid family metabolism Fumarylacetoacetate H000004_01 M55150 (external link) 73875 FAH (external link) 1.093 0.81499
35 0009072 aromatic amino acid family metabolism Quinoid dihydropteridine reductase H001542_01 M16447 (external link) 75438 QDPR (external link) 1.296 0.28212
36 0009072 aromatic amino acid family metabolism Phenylalanine hydroxylase H001632_01 U49897 (external link) 1870 PAH (external link) 0.51 0.12984
37 0046148 pigment biosynthesis Tyrosinase (oculocutaneous albinism IA) H003362_01 M27160 (external link) 2053 TYR (external link) 3.308 1e-04
38 0046148 pigment biosynthesis Silver (mouse homolog) like H003494_01 M77348 (external link) 95972 SILV (external link) 0.864 0.67214
39 0046148 pigment biosynthesis Ferrochelatase (protoporphyria) H005094_01 D00726 (external link) 26 FECH (external link) 0.67 0.18109
40 0046148 pigment biosynthesis Uroporphyrinogen III synthase (congenital erythropoietic porphyria) H000636_01 J03824 (external link) 75593 UROS (external link) 1.487 0.12987
41 0046148 pigment biosynthesis Aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) H008422_01 X60364 (external link) 323383 ALAS2 (external link) 1.085 0.87138
42 0046148 pigment biosynthesis Uroporphyrinogen decarboxylase H009835_01 AF104421 (external link) 78601 UROD (external link) 0.971 0.75631
43 0046148 pigment biosynthesis Aminolevulinate, delta-, synthase 1 H001696_01 Y00451 (external link) 78712 ALAS1 (external link) 1.093 0.65249
44 0000160 two-component signal transduction system (phosphorelay) Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 (external link) 431 BMI1 (external link) 0.857 0.38405
45 0000160 two-component signal transduction system (phosphorelay) BUP protein H008754_01 NM_012071 (external link) 35660 BUP (external link) 1.524 0.00307
46 0000160 two-component signal transduction system (phosphorelay) MMS19 (MET18 S. cerevisiae)-like H011462_01 AF007151 (external link) 288891 MMS19L (external link) 0.759 0.40935
47 0000160 two-component signal transduction system (phosphorelay) Hypothetical protein FLJ23132 H015444_01 NM_025054 (external link) 287727 FLJ23132 (external link) 0.933 0.62566
48 0000160 two-component signal transduction system (phosphorelay) Homo sapiens mRNA; cDNA DKFZp564I172 (from clone DKFZp564I172); complete CDS H015715_01 AL136635 (external link) 300816 0.726 0.08272
49 0016779 nucleotidyltransferase activity Unactive progesterone receptor, 23 kD H001846_01 L24804 (external link) 278270 P23 (external link) 1.03 0.89309
50 0016779 nucleotidyltransferase activity 3'-phosphoadenosine 5'-phosphosulfate synthase 1 H001876_01 AF105227 (external link) 3833 PAPSS1 (external link) 1.307 0.26494
51 0016779 nucleotidyltransferase activity Polymerase (DNA directed), gamma H001903_01 X98093 (external link) 80961 POLG (external link) 1.118 0.59162
52 0016779 nucleotidyltransferase activity 2'-5'oligoadenylate synthetase 2 H001966_01 M87284 (external link) 264981 OAS2 (external link) 0.744 0.50026
53 0016779 nucleotidyltransferase activity UDP-glucose pyrophosphorylase 2 H002258_01 U27460 (external link) 77837 UGP2 (external link) 1.189 0.63283
54 0016779 nucleotidyltransferase activity Proliferating cell nuclear antigen H002599_01 M15796 (external link) 78996 PCNA (external link) 0.875 0.66117
55 0016779 nucleotidyltransferase activity Telomerase reverse transcriptase H002699_01 AF015950 (external link) 115256 TERT (external link) 0.937 0.62951
56 0016779 nucleotidyltransferase activity Polymerase (DNA directed), beta H002879_01 D29013 (external link) 180107 POLB (external link) 1.092 0.77827
57 0016779 nucleotidyltransferase activity Polymerase (DNA directed), alpha H003792_01 X06745 (external link) 267289 POLA (external link) 0.935 0.80067
58 0016779 nucleotidyltransferase activity Galactose-1-phosphate uridylyltransferase H003947_01 M60091 (external link) 75641 GALT (external link) 1.672 0.12632
59 0016779 nucleotidyltransferase activity Topoisomerase-related function protein 4-1 H004233_01 AB005754 (external link) 225951 TRF4 (external link) 1.363 0.42912
60 0016779 nucleotidyltransferase activity UDP-N-acetylglucosamine pyrophosphorylase 1 H004589_01 AB011004 (external link) 21293 UAP1 (external link) 1.379 0.22684
61 0016779 nucleotidyltransferase activity Pericentriolar material 1 H004678_01 L27841 (external link) 75737 PCM1 (external link) 0.719 0.17315
62 0016779 nucleotidyltransferase activity Phosphate cytidylyltransferase 1, choline, beta isoform H004782_01 AF052510 (external link) 132794 PCYT1B (external link) 1.064 0.27452
63 0016779 nucleotidyltransferase activity Polymerase (RNA) III (DNA directed) (62kD) H004821_01 U93867 (external link) 250745 RPC62 (external link) 1.378 0.12697
64 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide B (140kD) H005570_01 X63563 (external link) 296014 POLR2B (external link) 0.429 0.00651
65 0016779 nucleotidyltransferase activity Ubiquitin specific protease 14 (tRNA-guanine transglycosylase) H006332_01 U30888 (external link) 75981 USP14 (external link) 0.898 0.65472
66 0016779 nucleotidyltransferase activity Nucleotide binding protein H006333_01 U18919 (external link) 296422 NBP (external link) 1.374 0.13261
67 0016779 nucleotidyltransferase activity Poly(A) polymerase alpha H006445_01 X76770 (external link) 49007 PAPOLA (external link) 1.457 0.0877
68 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide H H006451_01 U37689 (external link) 3128 POLR2H (external link) 1.246 0.1232
69 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) H006464_01 U37690 (external link) 71618 POLR2L (external link) 0.652 0.18083
70 0016779 nucleotidyltransferase activity Telomerase-associated protein 1 H006594_01 U86136 (external link) 232070 TEP1 (external link) 0.966 0.82723
71 0016779 nucleotidyltransferase activity Polymerase (DNA-directed), mu H006716_01 AJ131891 (external link) 46964 POLM (external link) 0.575 0.32178
72 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) H007101_01 L37127 (external link) 80475 POLR2J (external link) 0.765 0.1425
73 0016779 nucleotidyltransferase activity Hypothetical protein FLJ10509 H007616_01 AK001371 (external link) 274319 FLJ10509 (external link) 1.587 0.10474
74 0016779 nucleotidyltransferase activity Similar to DNA-directed RNA polymerase I (135 kDa) H007868_01 AK001678 (external link) 86337 FLJ10816 (external link) 0.838 0.24108
75 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) H007908_01 Z47727 (external link) 150675 POLR2K (external link) 0.891 0.67863
76 0016779 nucleotidyltransferase activity N-acetylneuraminic acid phosphate synthase; sialic acid synthase H008206_01 AK001659 (external link) 274424 SAS (external link) 0.779 0.36438
77 0016779 nucleotidyltransferase activity Polymerase (DNA directed), gamma 2, accessory subunit H008428_01 U94703 (external link) 30541 POLG2 (external link) 1.327 0.0338
78 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide A (220kD) H008768_01 X63564 (external link) 171880 POLR2A (external link) 1.279 0.41871
79 0016779 nucleotidyltransferase activity Polymerase (DNA directed), delta 2, regulatory subunit (50kD) H000074_01 U21090 (external link) 74598 POLD2 (external link) 1.102 0.70683
80 0016779 nucleotidyltransferase activity Histone fold protein CHRAC17; DNA polymerase epsilon p17 subunit H010753_01 AF070640 (external link) 108112 CHRAC17 (external link) 0.616 0.1856
81 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide E (25kD) H010908_01 D38251 (external link) 24301 POLR2E (external link) 0.821 0.37832
82 0016779 nucleotidyltransferase activity Transcriptional coactivator H011559_01 AF047002 (external link) 241520 ALY (external link) 0.756 0.17392
83 0016779 nucleotidyltransferase activity Dyskeratosis congenita 1, dyskerin H012214_01 AF067008 (external link) 4747 DKC1 (external link) 1.49 0.14225
84 0016779 nucleotidyltransferase activity Phosphate cytidylyltransferase 2, ethanolamine H012323_01 D84307 (external link) 226377 PCYT2 (external link) 0.542 0.17937
85 0016779 nucleotidyltransferase activity BN51 (BHK21) temperature sensitivity complementing H013188_01 M17754 (external link) 1276 BN51T (external link) 0.987 0.96033
86 0016779 nucleotidyltransferase activity CMP-N-acetylneuraminic acid synthase H014153_01 NM_018686 (external link) 12492 LOC55907 (external link) 0.962 0.89372
87 0016779 nucleotidyltransferase activity DNA polymerase epsilon p12 subunit H014636_01 NM_019896 (external link) 19980 P12 (external link) 0.666 0.17962
88 0016779 nucleotidyltransferase activity Hypothetical protein FLJ13390 similar to PAF53 H014829_01 NM_022490 (external link) 24884 FLJ13390 (external link) 0.988 0.97023
89 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide I (14.5kD) H016370_01 NM_006233 (external link) 47062 POLR2I (external link) 1.137 0.4602
90 0016779 nucleotidyltransferase activity X-ray repair complementing defective repair in Chinese hamster cells 3 H000124_01 AF035586 (external link) 99742 XRCC3 (external link) 1.422 0.23269
91 0051325 interphase Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 (external link) 82932 CCND1 (external link) 1.251 0.36936
92 0051325 interphase Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) 0.838 0.33129
93 0051325 interphase Cell division cycle 34 H002232_01 L22005 (external link) 76932 CDC34 (external link) 1.415 0.21701
94 0051325 interphase Cyclin E1 H002323_01 M74093 (external link) 9700 CCNE1 (external link) 1.288 0.47974
95 0051325 interphase Cyclin B1 H002371_01 M25753 (external link) 23960 CCNB1 (external link) 0.675 0.15891
96 0051325 interphase Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) 1.853 0.11588
97 0051325 interphase Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) H002606_01 L20320 (external link) 184298 CDK7 (external link) 1.055 0.83498
98 0051325 interphase Menage a trois 1 (CAK assembly factor) H000312_01 X87843 (external link) 82380 MNAT1 (external link) 0.689 0.32732
99 0051325 interphase Cyclin A2 H002740_01 X51688 (external link) 85137 CCNA2 (external link) 1.344 0.24008
100 0051325 interphase Cyclin G1 H002889_01 X77794 (external link) 79101 CCNG1 (external link) 0.613 0.00464
101 0051325 interphase Cell division cycle 25C H003048_01 M34065 (external link) 656 CDC25C (external link) 0.762 0.17709
102 0051325 interphase CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 (external link) 69563 CDC6 (external link) 1.021 0.86789
103 0051325 interphase V-abl Abelson murine leukemia viral oncogene homolog 1 H003207_01 NM_005157 (external link) 146355 ABL1 (external link) 1.038 0.88522
104 0051325 interphase General transcription factor IIH, polypeptide 1 (62kD subunit) H003500_01 M95809 (external link) 89578 GTF2H1 (external link) 1.304 0.40518
105 0051325 interphase Cullin 2 H000387_01 U83410 (external link) 82919 CUL2 (external link) 1.456 0.24367
106 0051325 interphase Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 (external link) 106070 CDKN1C (external link) 1.211 0.40117
107 0051325 interphase Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 (external link) 184572 CDC2 (external link) 0.503 0.10961
108 0051325 interphase Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) H003750_01 AF004819 (external link) 72901 CDKN2B (external link) 1.264 0.44457
109 0051325 interphase Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 (external link) 29656 CDKN2D (external link) 0.909 0.73706
110 0051325 interphase Chromosome condensation 1 H000401_01 X12654 (external link) 84746 CHC1 (external link) 0.789 0.22395
111 0051325 interphase Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) H004513_01 U28386 (external link) 159557 KPNA2 (external link) 0.832 0.76185
112 0051325 interphase Cell cycle progression 2 protein H000462_01 AF011792 (external link) 170980 CPR2 (external link) 0.794 0.28286
113 0051325 interphase CDC28 protein kinase 2 H000463_01 X54942 (external link) 83758 CKS2 (external link) 0.849 0.4051
114 0051325 interphase Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 (external link) 180059 1.389 0.13754
115 0051325 interphase RNA, U17D small nucleolar H005580_01 AJ006835 (external link) 196769 RNU17D (external link) 1.352 0.3504
116 0051325 interphase DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 (external link) 21189 DNAJA2 (external link) 1.364 0.12707
117 0051325 interphase Cullin 4A H006657_01 U58090 (external link) 183874 CUL4A (external link) 0.602 0.37343
118 0051325 interphase Cyclin-E binding protein 1 H007016_01 AB027289 (external link) 26663 LOC51191 (external link) 1.057 0.91297
119 0051325 interphase Deleted in oral cancer (mouse, homolog) 1 H000606_01 AF006484 (external link) 3436 DOC1 (external link) 0.941 0.64521
120 0051325 interphase G1 to S phase transition 1 H000607_01 X17644 (external link) 2707 GSPT1 (external link) 1.06 0.69634
121 0051325 interphase DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H007565_01 U75967 (external link) 27424 DDX11 (external link) 0.658 0.23892
122 0051325 interphase Cullin 5 H008068_01 X81882 (external link) 101299 CUL5 (external link) 0.892 0.48091
123 0051325 interphase Cullin 1 H008496_01 AF062536 (external link) 14541 CUL1 (external link) 0.824 0.17857
124 0051325 interphase Protein phosphatase 6, catalytic subunit H008575_01 X92972 (external link) 279563 PPP6C (external link) 0.688 0.19804
125 0051325 interphase Branched chain aminotransferase 1, cytosolic H008589_01 U21551 (external link) 157205 BCAT1 (external link) 1.516 0.15679
126 0051325 interphase GAP-associated tyrosine phosphoprotein p62 (Sam68) H009232_01 M88108 (external link) 119537 SAM68 (external link) 0.663 0.15228
127 0051325 interphase DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H009291_01 U75968 (external link) 27424 DDX11 (external link) 0.811 0.38746
128 0051325 interphase Cdk inhibitor p21 binding protein H010584_01 AB040450 (external link) 279862 TOK-1 (external link) 0.875 0.63115
129 0051325 interphase Anaphase-promoting complex subunit 5 H010633_01 NM_016237 (external link) 7101 APC5 (external link) 1.211 0.40229
130 0051325 interphase Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 (external link) 283948 0.858 0.22618
131 0051325 interphase Cyclin T2 H001491_01 AF048731 (external link) 155478 CCNT2 (external link) 0.884 0.75297
132 0051325 interphase Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) H001670_01 L25876 (external link) 84113 CDKN3 (external link) 0.581 0.10101
133 0051325 interphase Dynamin 2 H001738_01 L36983 (external link) 167013 DNM2 (external link) 1.065 0.74997
134 0051329 interphase of mitotic cell cycle Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 (external link) 82932 CCND1 (external link) 1.251 0.36936
135 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) 0.838 0.33129
136 0051329 interphase of mitotic cell cycle Cell division cycle 34 H002232_01 L22005 (external link) 76932 CDC34 (external link) 1.415 0.21701
137 0051329 interphase of mitotic cell cycle Cyclin E1 H002323_01 M74093 (external link) 9700 CCNE1 (external link) 1.288 0.47974
138 0051329 interphase of mitotic cell cycle Cyclin B1 H002371_01 M25753 (external link) 23960 CCNB1 (external link) 0.675 0.15891
139 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) 1.853 0.11588
140 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) H002606_01 L20320 (external link) 184298 CDK7 (external link) 1.055 0.83498
141 0051329 interphase of mitotic cell cycle Menage a trois 1 (CAK assembly factor) H000312_01 X87843 (external link) 82380 MNAT1 (external link) 0.689 0.32732
142 0051329 interphase of mitotic cell cycle Cyclin A2 H002740_01 X51688 (external link) 85137 CCNA2 (external link) 1.344 0.24008
143 0051329 interphase of mitotic cell cycle Cyclin G1 H002889_01 X77794 (external link) 79101 CCNG1 (external link) 0.613 0.00464
144 0051329 interphase of mitotic cell cycle Cell division cycle 25C H003048_01 M34065 (external link) 656 CDC25C (external link) 0.762 0.17709
145 0051329 interphase of mitotic cell cycle CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 (external link) 69563 CDC6 (external link) 1.021 0.86789
146 0051329 interphase of mitotic cell cycle V-abl Abelson murine leukemia viral oncogene homolog 1 H003207_01 NM_005157 (external link) 146355 ABL1 (external link) 1.038 0.88522
147 0051329 interphase of mitotic cell cycle General transcription factor IIH, polypeptide 1 (62kD subunit) H003500_01 M95809 (external link) 89578 GTF2H1 (external link) 1.304 0.40518
148 0051329 interphase of mitotic cell cycle Cullin 2 H000387_01 U83410 (external link) 82919 CUL2 (external link) 1.456 0.24367
149 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 (external link) 106070 CDKN1C (external link) 1.211 0.40117
150 0051329 interphase of mitotic cell cycle Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 (external link) 184572 CDC2 (external link) 0.503 0.10961
151 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) H003750_01 AF004819 (external link) 72901 CDKN2B (external link) 1.264 0.44457
152 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 (external link) 29656 CDKN2D (external link) 0.909 0.73706
153 0051329 interphase of mitotic cell cycle Chromosome condensation 1 H000401_01 X12654 (external link) 84746 CHC1 (external link) 0.789 0.22395
154 0051329 interphase of mitotic cell cycle Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) H004513_01 U28386 (external link) 159557 KPNA2 (external link) 0.832 0.76185
155 0051329 interphase of mitotic cell cycle Cell cycle progression 2 protein H000462_01 AF011792 (external link) 170980 CPR2 (external link) 0.794 0.28286
156 0051329 interphase of mitotic cell cycle CDC28 protein kinase 2 H000463_01 X54942 (external link) 83758 CKS2 (external link) 0.849 0.4051
157 0051329 interphase of mitotic cell cycle Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 (external link) 180059 1.389 0.13754
158 0051329 interphase of mitotic cell cycle RNA, U17D small nucleolar H005580_01 AJ006835 (external link) 196769 RNU17D (external link) 1.352 0.3504
159 0051329 interphase of mitotic cell cycle DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 (external link) 21189 DNAJA2 (external link) 1.364 0.12707
160 0051329 interphase of mitotic cell cycle Cullin 4A H006657_01 U58090 (external link) 183874 CUL4A (external link) 0.602 0.37343
161 0051329 interphase of mitotic cell cycle Cyclin-E binding protein 1 H007016_01 AB027289 (external link) 26663 LOC51191 (external link) 1.057 0.91297
162 0051329 interphase of mitotic cell cycle Deleted in oral cancer (mouse, homolog) 1 H000606_01 AF006484 (external link) 3436 DOC1 (external link) 0.941 0.64521
163 0051329 interphase of mitotic cell cycle G1 to S phase transition 1 H000607_01 X17644 (external link) 2707 GSPT1 (external link) 1.06 0.69634
164 0051329 interphase of mitotic cell cycle DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H007565_01 U75967 (external link) 27424 DDX11 (external link) 0.658 0.23892
165 0051329 interphase of mitotic cell cycle Cullin 5 H008068_01 X81882 (external link) 101299 CUL5 (external link) 0.892 0.48091
166 0051329 interphase of mitotic cell cycle Cullin 1 H008496_01 AF062536 (external link) 14541 CUL1 (external link) 0.824 0.17857
167 0051329 interphase of mitotic cell cycle Protein phosphatase 6, catalytic subunit H008575_01 X92972 (external link) 279563 PPP6C (external link) 0.688 0.19804
168 0051329 interphase of mitotic cell cycle Branched chain aminotransferase 1, cytosolic H008589_01 U21551 (external link) 157205 BCAT1 (external link) 1.516 0.15679
169 0051329 interphase of mitotic cell cycle GAP-associated tyrosine phosphoprotein p62 (Sam68) H009232_01 M88108 (external link) 119537 SAM68 (external link) 0.663 0.15228
170 0051329 interphase of mitotic cell cycle DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H009291_01 U75968 (external link) 27424 DDX11 (external link) 0.811 0.38746
171 0051329 interphase of mitotic cell cycle Cdk inhibitor p21 binding protein H010584_01 AB040450 (external link) 279862 TOK-1 (external link) 0.875 0.63115
172 0051329 interphase of mitotic cell cycle Anaphase-promoting complex subunit 5 H010633_01 NM_016237 (external link) 7101 APC5 (external link) 1.211 0.40229
173 0051329 interphase of mitotic cell cycle Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 (external link) 283948 0.858 0.22618
174 0051329 interphase of mitotic cell cycle Cyclin T2 H001491_01 AF048731 (external link) 155478 CCNT2 (external link) 0.884 0.75297
175 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) H001670_01 L25876 (external link) 84113 CDKN3 (external link) 0.581 0.10101
176 0051329 interphase of mitotic cell cycle Dynamin 2 H001738_01 L36983 (external link) 167013 DNM2 (external link) 1.065 0.74997
177 0000080 G1 phase of mitotic cell cycle Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) 1.853 0.11588
178 0000080 G1 phase of mitotic cell cycle Cell division cycle 25C H003048_01 M34065 (external link) 656 CDC25C (external link) 0.762 0.17709
179 0000080 G1 phase of mitotic cell cycle CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 (external link) 69563 CDC6 (external link) 1.021 0.86789
180 0000080 G1 phase of mitotic cell cycle Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 (external link) 106070 CDKN1C (external link) 1.211 0.40117
181 0000080 G1 phase of mitotic cell cycle Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 (external link) 184572 CDC2 (external link) 0.503 0.10961
182 0000080 G1 phase of mitotic cell cycle Cell cycle progression 2 protein H000462_01 AF011792 (external link) 170980 CPR2 (external link) 0.794 0.28286
183 0000080 G1 phase of mitotic cell cycle Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 (external link) 180059 1.389 0.13754
184 0000080 G1 phase of mitotic cell cycle DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 (external link) 21189 DNAJA2 (external link) 1.364 0.12707
185 0000080 G1 phase of mitotic cell cycle Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 (external link) 283948 0.858 0.22618
186 0051318 G1 phase Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) 1.853 0.11588
187 0051318 G1 phase Cell division cycle 25C H003048_01 M34065 (external link) 656 CDC25C (external link) 0.762 0.17709
188 0051318 G1 phase CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 (external link) 69563 CDC6 (external link) 1.021 0.86789
189 0051318 G1 phase Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 (external link) 106070 CDKN1C (external link) 1.211 0.40117
190 0051318 G1 phase Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 (external link) 184572 CDC2 (external link) 0.503 0.10961
191 0051318 G1 phase Cell cycle progression 2 protein H000462_01 AF011792 (external link) 170980 CPR2 (external link) 0.794 0.28286
192 0051318 G1 phase Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 (external link) 180059 1.389 0.13754
193 0051318 G1 phase DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 (external link) 21189 DNAJA2 (external link) 1.364 0.12707
194 0051318 G1 phase Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 (external link) 283948 0.858 0.22618
195 0019199 transmembrane receptor protein kinase activity Discoidin domain receptor family, member 2 H001908_01 X74764 71891 DDR2 (external link) 0.831 0.53593
196 0019199 transmembrane receptor protein kinase activity V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 H002029_01 M34309 (external link) 199067 ERBB3 (external link) 1.307 0.48426
197 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) H002119_01 X66945 (external link) 748 FGFR1 (external link) 0.861 0.34712
198 0019199 transmembrane receptor protein kinase activity Ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hir H002140_01 X12949 (external link) 287270 RET (external link) 0.828 0.65442
199 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, H002197_01 M87770 (external link) 278581 FGFR2 (external link) 1.129 0.68541
200 0019199 transmembrane receptor protein kinase activity Neurotrophic tyrosine kinase, receptor, type 1 H002234_01 M23102 (external link) 85844 NTRK1 (external link) 0.765 0.17994
201 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) H002448_01 M64347 (external link) 1420 FGFR3 (external link) 1.597 0.05694
202 0019199 transmembrane receptor protein kinase activity Fms-related tyrosine kinase 4 H002485_01 X69878 (external link) 74049 FLT4 (external link) 0.756 0.37366
203 0019199 transmembrane receptor protein kinase activity Activin A receptor, type IIB H002488_01 X77533 (external link) 23994 ACVR2B (external link) 0.642 0.03331
204 0019199 transmembrane receptor protein kinase activity EphA1 H002568_01 M18391 (external link) 89839 EPHA1 (external link) 0.961 0.83855
205 0019199 transmembrane receptor protein kinase activity Kinase insert domain receptor (a type III receptor tyrosine kinase) H002712_01 AF035121 (external link) 12337 KDR (external link) 0.74 0.11432
206 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 4 H002756_01 L03840 (external link) 165950 FGFR4 (external link) 0.649 0.23236
207 0019199 transmembrane receptor protein kinase activity Platelet-derived growth factor receptor, alpha polypeptide H002775_01 M21574 (external link) 74615 PDGFRA (external link) 1.096 0.25256
208 0019199 transmembrane receptor protein kinase activity Ret finger protein H000323_01 J03407 (external link) 142653 RFP (external link) 0.784 0.31172
209 0019199 transmembrane receptor protein kinase activity Macrophage stimulating 1 receptor (c-met-related tyrosine kinase) H002936_01 X70040 (external link) 2942 MST1R (external link) 1.543 0.12996
210 0019199 transmembrane receptor protein kinase activity Discoidin domain receptor family, member 1 H002955_01 NM_013994 (external link) 75562 DDR1 (external link) 0.792 0.55617
211 0019199 transmembrane receptor protein kinase activity Insulin-like growth factor 2 receptor H003016_01 Y00285 (external link) 76473 IGF2R (external link) 0.813 0.33053
212 0019199 transmembrane receptor protein kinase activity Ephrin-A4 H003069_01 AJ006352 (external link) 42331 EFNA4 (external link) 1.67 0.1254
213 0019199 transmembrane receptor protein kinase activity EphB4 H003096_01 U07695 (external link) 155227 EPHB4 (external link) 0.849 0.29767
214 0019199 transmembrane receptor protein kinase activity RYK receptor-like tyrosine kinase H003160_01 S59184 (external link) 79350 RYK (external link) 0.838 0.49926
215 0019199 transmembrane receptor protein kinase activity V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene H003542_01 M11730 (external link) 323910 ERBB2 (external link) 1.004 0.98391
216 0019199 transmembrane receptor protein kinase activity Neurotrophic tyrosine kinase, receptor, type 3 H003588_01 U05012 (external link) 26776 NTRK3 (external link) 1.151 0.20942
217 0019199 transmembrane receptor protein kinase activity Platelet-derived growth factor receptor, beta polypeptide H003752_01 J03278 (external link) 76144 PDGFRB (external link) 1.509 0.21888
218 0019199 transmembrane receptor protein kinase activity PTK7 protein tyrosine kinase 7 H003804_01 U33635 (external link) 90572 PTK7 (external link) 1.351 0.22758
219 0019199 transmembrane receptor protein kinase activity V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog H003808_01 X06182 (external link) 81665 KIT (external link) 0.788 0.49109
220 0019199 transmembrane receptor protein kinase activity Activin A receptor, type IB H003853_01 Z22536 (external link) 99954 ACVR1B (external link) 1.179 0.26984
221 0019199 transmembrane receptor protein kinase activity C-mer proto-oncogene tyrosine kinase H000425_01 U08023 (external link) 306178 MERTK (external link) 0.944 0.86201
222 0019199 transmembrane receptor protein kinase activity Homo sapiens cDNA FLJ11309 fis, clone PLACE1010076 H006813_01 AK002171 (external link) 28005 1.2 0.52528
223 0019199 transmembrane receptor protein kinase activity Latent transforming growth factor beta binding protein 1 H000940_01 M34057 (external link) 241257 LTBP1 (external link) 0.82 0.49965
224 0019199 transmembrane receptor protein kinase activity Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial CDS H013267_01 U88358 (external link) 306251 1.182 0.39888
225 0019199 transmembrane receptor protein kinase activity Platelet-derived growth factor receptor-like H001341_01 D37965 (external link) 170040 PDGFRL (external link) 0.652 0.09963
226 0000082 G1/S transition of mitotic cell cycle Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 (external link) 82932 CCND1 (external link) 1.251 0.36936
227 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) 0.838 0.33129
228 0000082 G1/S transition of mitotic cell cycle Cell division cycle 34 H002232_01 L22005 (external link) 76932 CDC34 (external link) 1.415 0.21701
229 0000082 G1/S transition of mitotic cell cycle Cyclin E1 H002323_01 M74093 (external link) 9700 CCNE1 (external link) 1.288 0.47974
230 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) H002606_01 L20320 (external link) 184298 CDK7 (external link) 1.055 0.83498
231 0000082 G1/S transition of mitotic cell cycle Menage a trois 1 (CAK assembly factor) H000312_01 X87843 (external link) 82380 MNAT1 (external link) 0.689 0.32732
232 0000082 G1/S transition of mitotic cell cycle Cyclin A2 H002740_01 X51688 (external link) 85137 CCNA2 (external link) 1.344 0.24008
233 0000082 G1/S transition of mitotic cell cycle Cyclin G1 H002889_01 X77794 (external link) 79101 CCNG1 (external link) 0.613 0.00464
234 0000082 G1/S transition of mitotic cell cycle Cell division cycle 25C H003048_01 M34065 (external link) 656 CDC25C (external link) 0.762 0.17709
235 0000082 G1/S transition of mitotic cell cycle CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 (external link) 69563 CDC6 (external link) 1.021 0.86789
236 0000082 G1/S transition of mitotic cell cycle General transcription factor IIH, polypeptide 1 (62kD subunit) H003500_01 M95809 (external link) 89578 GTF2H1 (external link) 1.304 0.40518
237 0000082 G1/S transition of mitotic cell cycle Cullin 2 H000387_01 U83410 (external link) 82919 CUL2 (external link) 1.456 0.24367
238 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 (external link) 106070 CDKN1C (external link) 1.211 0.40117
239 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) H003750_01 AF004819 (external link) 72901 CDKN2B (external link) 1.264 0.44457
240 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 (external link) 29656 CDKN2D (external link) 0.909 0.73706
241 0000082 G1/S transition of mitotic cell cycle Chromosome condensation 1 H000401_01 X12654 (external link) 84746 CHC1 (external link) 0.789 0.22395
242 0000082 G1/S transition of mitotic cell cycle CDC28 protein kinase 2 H000463_01 X54942 (external link) 83758 CKS2 (external link) 0.849 0.4051
243 0000082 G1/S transition of mitotic cell cycle RNA, U17D small nucleolar H005580_01 AJ006835 (external link) 196769 RNU17D (external link) 1.352 0.3504
244 0000082 G1/S transition of mitotic cell cycle Cullin 4A H006657_01 U58090 (external link) 183874 CUL4A (external link) 0.602 0.37343
245 0000082 G1/S transition of mitotic cell cycle Cyclin-E binding protein 1 H007016_01 AB027289 (external link) 26663 LOC51191 (external link) 1.057 0.91297
246 0000082 G1/S transition of mitotic cell cycle G1 to S phase transition 1 H000607_01 X17644 (external link) 2707 GSPT1 (external link) 1.06 0.69634
247 0000082 G1/S transition of mitotic cell cycle Cullin 5 H008068_01 X81882 (external link) 101299 CUL5 (external link) 0.892 0.48091
248 0000082 G1/S transition of mitotic cell cycle Cullin 1 H008496_01 AF062536 (external link) 14541 CUL1 (external link) 0.824 0.17857
249 0000082 G1/S transition of mitotic cell cycle Protein phosphatase 6, catalytic subunit H008575_01 X92972 (external link) 279563 PPP6C (external link) 0.688 0.19804
250 0000082 G1/S transition of mitotic cell cycle Branched chain aminotransferase 1, cytosolic H008589_01 U21551 (external link) 157205 BCAT1 (external link) 1.516 0.15679
251 0000082 G1/S transition of mitotic cell cycle GAP-associated tyrosine phosphoprotein p62 (Sam68) H009232_01 M88108 (external link) 119537 SAM68 (external link) 0.663 0.15228
252 0000082 G1/S transition of mitotic cell cycle Cdk inhibitor p21 binding protein H010584_01 AB040450 (external link) 279862 TOK-1 (external link) 0.875 0.63115
253 0000082 G1/S transition of mitotic cell cycle Cyclin T2 H001491_01 AF048731 (external link) 155478 CCNT2 (external link) 0.884 0.75297
254 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) H001670_01 L25876 (external link) 84113 CDKN3 (external link) 0.581 0.10101
255 0030934 anchoring collagen Collagen, type VI, alpha 3 H001981_01 X52022 (external link) 80988 COL6A3 (external link) 1.236 0.26989
256 0030934 anchoring collagen Collagen, type XVI, alpha 1 H002090_01 M92642 (external link) 26208 COL16A1 (external link) 1.157 0.19594
257 0030934 anchoring collagen Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) H002655_01 L02870 (external link) 1640 COL7A1 (external link) 1.292 0.26637
258 0030934 anchoring collagen Collagen, type VI, alpha 1 H000774_01 X15880 (external link) 108885 COL6A1 (external link) 1.311 0.20447
259 0030934 anchoring collagen Homo sapiens, alpha-1 (VI) collagen H001198_01 M20776 (external link) 25459 1.299 0.34272