Biography

National Services:

  • 2001 – 2006 – Member of the National Institute of Health Grant Review Study Section – Brain Disorders and Clinical Neuroscience 1 (BDCN-1/CND)
  • October 2003 – Invited Participant -NIH-NINDS – Priorities for Clinical Research in the Treatment of Acute, non-Traumatic Intracerebral Hemorrhage Workshop, 2003. The panel was established to create new guidelines for research in ICH treatment
  • November 2003 – Invited speaker, NIH-NINDS Stroke Conference
  • 2004 – 2009 – Brain 2 – American Heart Association- grant review panel (co-chairman of the study group)
  • November 2005 – NINDS Special Emphasis Panel ZNS1 SRB-M Study Section
  • 2005 – Advisory Board member for the 1st International Symposium on Cerebral Hemorrhage. Ann Arbor, Michigan
  • November 2006 – Planning Committee member – NIH, NINDS Workshop on Models of Geriatric Epilepsy
  • April 2006 – Loan Repayment Program NIH Study Sections – 2006/08 ZNS1 SRB-M (35)
  • 2006 – Present – Fellowship (F30) NIH-NINDS Study Section – 2006/08 ZNS1 SRB-M (36)
  • 2006 – Stroke Progress Review Group (SPRG) – Topic – Intracerebral Hemorrhage advisory panel – NIH, NINDS. The panel was established to create new research and clinical recommendations to NIH
  • November 2006 – Fellowship (F30/F05) NIH-NINDS grant review study section – 2007/01 ZNS1 SRB-M (39)
  • 2007 – Advisory Board Member for the 2nd International Symposium on Cerebral Hemorrhage
  • 2007 – Organizing Committee, 26th Princeton Conference on Cerebrovascular Disease, Houston, Texas
  • March 2008 – NIH/NINDS – Special Emphasis Panel/Scientific Review 2008/05 ZNS1 SRB-M (57)
  • September 2008 NIH 10 ZRG1 BDCN-N (93) S Neurodegenerative Disorders and Injury
  • October 2008 – present, NIH, NINDS, Charter Member – Neurological Sciences Training Initial Review Group, NST-2 (F30 and K99 awards)
  • June 2009 – NIH – RFA-OD-09-003 Challenge Grant Panel 11
  • October 2009 – NIH – Acute Neural Injury and Epilepsy Study Section (ANIE) Brain Disorders and Clinical Neuroscience Integrated Review Group
  • February 2010 – Invited Moderator of a session on “Hemorrhage – Intraparenchymal” – International Stroke Conference, San Antonio, Texas
  • March 2010 – Invited Chairman of the session on Hematoma Resolution – International Intracerebral Hemorrhage Conference, Palm Springs, CA
  • April 2010 – Invited Speaker at 27th Princeton Conferences on Cerebrovascular Disease, Boston, MA
  • July 2010 – Invited lectures at the symposium “Nuclear receptors”; WorldPharma2010, Copenhagen, Denmark
  • March 2011 – Invited lectures at the 2nd Venusberg Meeting on Neuroinflammation. Bonn. Germany.
  • June 2011 – NIH – Acute Neural Injury and Epilepsy Study Section (ANIE) Brain Disorders and Clinical Neuroscience Integrated Review Group
  • 2011 – NIH, NINDS. Stroke Progress Review Group (SPRG) – Topic – Intracerebral Hemorrhage advisory panel –The panel was established to create new research and clinical recommendations to NIH. Co-Chairman of the panel.
  • 2011 – 2015, Board of Directors of the International Society for Cerebral Blood Flow and Metabolism (ISCBFM).
  • August 2012 – Member of Planning Group to Establish NIH Future Goals/Priorities in Stroke Research – NIH, NINDS. Stroke Progress Review Group (SPRG), Bethesda.
  • September 2012, NIH. ZRG1 BDCN-W 02, Brain Disorders and Clinical Neuroscience Integrated Review Group
  •  August 2012 – Gordon Research Conference — Brain Energy Metabolism and Blood Flow – Chairman of the “Neuroinflammation” session
  • November, 2012 – NIH-NINDS Neurological Sciences and Disorders K (NSD-K) review panel and ZNS1 SRB-G (62) PHASE III CLINICAL TRIALS
  • April 2013 – NIH- Special Emphasis Panel/Scientific Review Group 2013/05 ZNS1 SRB-G (65)
  • June 2013. NIH – ZRG1 BDCN-N (55) RPAR Panel: Brain Disorders in the Developing World Research Across the Lifespan
  • November 2013. NIH-NINDS Neurological Sciences and Disorders K (NSD-K) review panel. PHASE III CLINICAL TRIALS
  • November, 2013 – 2 NIH-NINDS 014/01 ZNS1 SRB-G (73); NEURONEXTEXT SEP – review committee
  • June 2014. NIH (CSR) – Brain Injury and Neurovascular Pathologies Study Section (BINP) – review committee

Education

Medical Degree
Medical Academy of Warsaw, Warsaw, Poland
Doctorate
Polish Academy of Sciences, Warsaw, Poland
Instructor
Department of Pharmacodynamics, The Institute of Physiology, Warsaw, Poland

Research Information

  • Neuropharmacology and laboratory models of ischemic stroke and intracerebral hemorrhage
  • His research involves understanding the cellular and molecular mechanisms underlying the pathology of acute cerebral ischemia, reperfusion injury and intracerebral hemorrhage, with emphasis on calcium related signal transduction, adenosine receptors, protein phosphorylation, transcription factors (specifically NF-kappaB, Nrf2 and PPAR) and neuroinflammation (including role of microglia and macrophages in hematoma resolution)
  • Utilizing behavioral modalities in our animal injury models, he is also investigating the effect of motor and cognitive activities on neuronal plasticity and functional recovery from stroke-induced brain damage. Also, using relevant animal models, including knockout mice, he is evaluating new clinically relevant experimental pharmacotherapies with different mechanisms of action targeting the acute and recovery phase of stroke and ICH pathology
  • Ongoing projects supported by the NIH include:
    1. Inflammatory/Immunological response regulation by transcription factors after ICH
    2. Role of transcription factor PPAR-gamma in neuroprotection after ischemic stroke
    3. Role of rehabilitation in brain re-wiring after stroke
    4. Role of transcription factor Nrf2 in neuroprotection after intracerebral hemorrhage
    5. Role of immune cells (e.g. regulatory T-cell) in post-stroke recovery
    6. Use of stem cells in post stroke recovery