Education

Neonatal-Perinatal Medicine Fellowship
University of Iowa
Pediatric Residency
University of Iowa
Pediatric Residency
University of Wisconsin
Certificate in Biostatistics
University of Iowa
PhD Epidemiology
University of Iowa
MD Medicine
University of Iowa
BS Biomedical Engineering
Saint Louis University

Publications

  • Romero-Lopez, M., Naik, M., Holzapfel, L.F. Tyson L., Pedroza, C., Ahmad, K.A., Rysavy, M.A., Carlo, W.A., Zhang, Y., Tibe, C., and Salas, K.A. Enteral nutritional practices in extremely preterm infants: a survey of U.S. NICUs. J Perinatol (2024). https://doi.org/10.1038/s41372-024-02198-6
  • Li L, Rysavy MA, Bobashev G, Das A. Comparing methods for risk prediction of multicategory outcomes: dichotomized logistic regression vs. multinomial logit regression. BMC Med Res Methodol. 2024 Oct 31;24(1):261. doi: 10.1186/s12874-024-02389-x. PMID: 39482630; PMCID: PMC11526521.
  • Boghossian NS, Mack NA, Bell EF, Tan S, Stoll BJ, Rysavy MA, Ambalavanan N, Tyson JE, Das A, Hintz SR; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Trends in sex differences in neurodevelopmental outcomes among extremely preterm infants. Arch Dis Child Fetal Neonatal Ed. 2024 Sep 20:fetalneonatal-2024-327239. doi: 10.1136/archdischild-2024-327239. Epub ahead of print. PMID: 39288987.
  • Speer, Allison L. MD; Lally, Kevin P. MD, MS; Pedroza, Claudia PhD; Zhang, Yuxin MSc; Poindexter, Brenda B. MD, MS; Chwals, Walter J. MD; Hintz, Susan R. MD, MS; Besner, Gail E. MD; Stevenson, David K. MD; Ohls, Robin K. MD; Truog, William E. MD; Stoll, Barbara J. MD; Rysavy, Matthew A. MD, PhD; Das, Abhik PhD; Tyson, Jon E. MD, MPH; Blakely, Martin L. MD, MS; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Surgical Necrotizing Enterocolitis and Spontaneous Intestinal Perforation Lead to Severe Growth Failure in Infants. Annals of Surgery 280(3):p 432-443, September 2024. | DOI: 10.1097/SLA.0000000000006378
  • Romero-Lopez, M., Naik, M., Holzapfel, L.F. Salas, A.A, Ahmad, K.A., Rysavy, M.A., Carlo, W.A., Zhang, Y., Tibe, C., Tyson J.E. Survey of vitamin D supplementation practices in extremely preterm infants. Pediatr Res (2024). https://doi.org/10.1038/s41390-024-03514-8
  • Rysavy MA, Battarbee AN, Gibson KS. Four Important Questions About Between-Hospital Differences in Care at <25 Weeks’ Gestation. Pediatrics. 2024 Aug 12:e2024066182. doi: 10.1542/peds.2024-066182. Epub ahead of print. PMID: 39129508.
  • Jensen EA, DeMauro SB, Rysavy MA, Patel RM, Laughon MM, Eichenwald EC, Do BT, Das A, Wright CJ; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Acetaminophen for Patent Ductus Arteriosus and Risk of Mortality and Pulmonary Morbidity. Pediatrics. 2024 Jul 16:e2023065056. doi: 10.1542/peds.2023-065056. Epub ahead of print. PMID: 39011550.
  • Romero-Lopez M, Tyson JE, Naik M, Pedroza C, Holzapfel LF, Avritscher E, Mosquera R, Khan A, Rysavy M. Randomized controlled trial of enteral vitamin D supplementation (ViDES) in infants <28 weeks gestational age or <1000 g birth weight: study protocol. Trials. 2024 Jun 28;25(1):423. doi: 10.1186/s13063-024-08274-8. PMID: 38943179.
  • Jain VG, Parikh NA, Rysavy MA, Shukla VV, Trotta M, Jobe A, Carlo WA, Ambalavanan N. Histological Chorioamnionitis Increases the Risk of Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2024 May 15;209(10):1272-1275. doi: 10.1164/rccm.202311-2084LE. PMID: 38416515; PMCID: PMC11146533.
  • Wootton SH, Rysavy M, Davis P, Thio M, Romero-Lopez M, Holzapfel LF, et al. Practical approaches for supporting informed consent in neonatal clinical trials. Acta Paediatr. 2024;00:1–8. https://doi. org/10.1111/apa.17165
  • Shukla VV, Carper BA, Ambalavanan N, Rysavy MA, Bell EF, Das A, Patel RM, D’Angio CT, Watterberg KL, Cotten CM, Merhar SL, Wyckoff MH, Sánchez PJ, Kumbhat N, Carlo WA; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Social distancing and extremely preterm births in the initial COVID-19 pandemic period. J Perinatol. 2024 Feb 22. doi: 10.1038/s41372-024-01898-3. Epub ahead of print. PMID: 38388715.

  • Rysavy MA, Bennett MM, Ahmad KA, et al. Neonatal Intensive Care Unit Resource Use for Infants at 22 Weeks’ Gestation in the US, 2008-2021. JAMA Netw Open. 2024;7(2):e240124. doi:10.1001/jamanetworkopen.2024.0124

  • Goodman DC, Stuchlik P, Ganduglia-Cazaban C, Tyson JE, Leyenaar J, Avritscher EBC, Rysavy M, Gautham KS, Lynch D, Stukel TA; Texas Neonatal Care Research Collaborative. Hospital-Level NICU Capacity, Utilization, and 30-Day Outcomes in Texas. JAMA Netw Open. 2024 Feb 5;7(2):e2355982. doi: 10.1001/jamanetworkopen.2023.55982. PMID: 38353952; PMCID: PMC10867701.

  • Kaluarachchi DC, Rysavy MA, Carper BA, Chock VY, Laughon MM, Backes CH, Colaizy TT, Bell EF, McNamara PJ. Secular Trends in Patent Ductus Arteriosus Management in Infants Born Preterm in the NICHD Neonatal Research Network. J Pediatr. 2023 Dec 20:113877. doi: 10.1016/j.jpeds.2023.113877. Epub ahead of print. PMID: 38135028.
  • Baba A, Webbe J, Butcher NJ, Rodrigues C, Stallwood E, Goren K, Monsour A, Chang ASM, Trivedi A, Manley BJ, McCall E, Bogossian F, Namba F, Schmölzer GM, Harding J, Nguyen KA, Doyle LW, Jardine L, Rysavy MA, Konstantinidis M, Meyer M, Helmi MAM, Lai NM, Hay S, Onland W, Choo YM, Gale C, Soll RF, Offringa M; Core Outcome Reporting in Neonatal Trials Study Group. Heterogeneity and Gaps in Reporting Primary Outcomes From Neonatal Trials. Pediatrics. 2023 Sep 1;152(3):e2022060751. doi: 10.1542/peds.2022-060751. PMID: 37641881.
  • Green CE, Tyson JE, Heyne RJ, Hintz SR, Vohr BR, Bann CM, Das A, Bell EF, Debsareea SB, Stephens E, Gantz MG, Petrie Huitema CM, Johnson KJ, Watterberg KL, Mosquera R, Peralta-Carcelen M, Wilson-Costello DE, Colaizy TT, Maitre NL, Merhar SL, Adams-Chapman I, Fuller J, Hartley-McAndrew ME, Malcolm WF, Winter S, Duncan AF, Myer GJ, Kicklighter SD, Wyckoff MH, DeMauro SB, Hibbs AM, Stoll BJ, Carlo WA, Van Meurs KP, Rysavy MA, Patel RM, Sánchez PJ, Laptook AR, Cotten CM, D’Angio CT, Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study. J Perinatol. 2023 Nov;43(11):1398-1405. doi: 10.1038/s41372-023-01729-x. Epub 2023 Aug 4. PMID: 37542155; PMCID: PMC10615749.
  • Jensen EA, Wiener LE, Rysavy MA, Dysart KC, Gantz MG, Eichenwald EC, Greenberg RG, Harmon HM, Laughon MM, Watterberg KL, Walsh MC, Yoder BA, Lorch SA, DeMauro SB; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Assessment of Corticosteroid Therapy and Death or Disability According to Pretreatment Risk of Death or Bronchopulmonary Dysplasia in Extremely Preterm Infants. JAMA Netw Open. 2023 May 1;6(5):e2312277. doi: 10.1001/jamanetworkopen.2023.12277. PMID: 37155165; PMCID: PMC10167571.
  • Evans PT, Blakely ML, Mixon AS, Canvasser J, Rysavy MA, Fernandez ME, Pedroza C, Tyson JE. The evidence base for surgical treatment of infants with necrotizing enterocolitis or spontaneous intestinal perforation: Impact of trial design and questions regarding implementation of trial recommendations. Semin Pediatr Surg. 2023 Jun;32(3):151304. doi: 10.1016/j.sempedsurg.2023.151304. Epub 2023 May 24. PMID: 37276785.
  • Rysavy MA, Eggleston B, Dahabreh I, Tyson JE, Patel RM, Watterberg KL, Greenberg RG, Pedroza C, Trotta M, Stevenson DK, Stoll BJ, Lally KP, Das A, Blakely ML; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Generalizability of the Necrotizing Enterocolitis Surgery Trial (NEST) to the Target Population of Eligible Infants. J Pediatr. 2023 May 9:113453. doi: 10.1016/j.jpeds.2023.113453. Epub ahead of print. PMID: 37169336.
  • Sewell EK, Shankaran S, Natarajan G, Laptook A, Das A, McDonald SA, Hamrick S, Baack M, Rysavy M, Higgins RD, Chalak L, Patel RM. Evaluation of heterogeneity in effect of therapeutic hypothermia by sex among infants with neonatal encephalopathy. Pediatr Res. 2023 Apr 3. doi: 10.1038/s41390-023-02586-2. Epub ahead of print. PMID: 37012412.
  • Holzapfel L, Arnold C, Tyson J, Shapiro S, Reynolds E, Pedroza C, Stephens E, Kleinfeld A, Huber A, Rysavy M, Khan A, Lopez MDMR. Effect of Reduced Versus Usual Lipid Emulsion Dosing on Bilirubin Neurotoxicity and Neurodevelopmental Impairment in Extremely Preterm Infants: Study Protocol for a Randomized Controlled Trial. Res Sq [Preprint]. 2023 Mar 7:rs.3.rs-2566352. doi: 10.21203/rs.3.rs-2566352/v1. PMID: 36945475; PMCID: PMC10029123.
  • Dryer RA, Salem A, Saroha V, Greenberg RG, Rysavy MA, Chawla S, Patel RM. Evaluation and validation of a prediction model for extubation success in very preterm infants. J Perinatol. 2022 Sep 24. doi: 10.1038/s41372-022-01517-z. Epub ahead of print. PMID: 36153409.
  • Chawla S, Wyckoff MH, Rysavy MA, Patel RM, Chowdhury D, Natarajan G, Laptook AR, Lakshminrusimha S, Bell EF, Shankaran S, Van Meurs KP, Ambalavanan N, Greenberg RG, Younge N, Werner EF, Das A, Carlo WA; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Association of Antenatal Steroid Exposure at 21 to 22 Weeks of Gestation With Neonatal Survival and Survival Without Morbidities. JAMA Netw Open. 2022 Sep 1;5(9):e2233331. doi: 10.1001/jamanetworkopen.2022.33331. PMID: 36156145.
  • Blakely ML, Rysavy MA, Lally KP, Eggleston B, Pedroza C, Tyson JE. Special considerations in randomized trials investigating neonatal surgical treatments [published online ahead of print, 2022 Jun 10]. Semin Perinatol. 2022;151640. doi:10.1016/j.semperi.2022.151640
  • Bell EF, Stoll BJ, Hansen NI, et al. Contributions of the NICHD neonatal research network’s generic database to documenting and advancing the outcomes of extremely preterm infants [published online ahead of print, 2022 Jun 10]. Semin Perinatol. 2022;151635. doi:10.1016/j.semperi.2022.151635
  • Bouey NJ, Saha S, Wilson-Costello DE, et al. Delayed-interval delivery in multiple gestation pregnancies: neonatal mortality, morbidity, and development [published online ahead of print, 2022 Jul 29]. J Perinatol. 2022;10.1038/s41372-022-01462-x. doi:10.1038/s41372-022-01462-x
  • Chen X, Lu T, Gould J, et al. Active treatment of infants born at 22-25 weeks of gestation in California, 2011-2018 [published online ahead of print, 2022 Jun 14]. J Pediatr. 2022;S0022-3476(22)00546-7. doi:10.1016/j.jpeds.2022.06.013
  • Travers CP, Hansen NI, Das A, et al. Potential missed opportunities for antenatal corticosteroid exposure and outcomes among periviable births: observational cohort study [published online ahead of print, 2022 May 24]. BJOG. 2022;10.1111/1471-0528.17230. doi:10.1111/1471-0528.17230
  • Bane S, Rysavy MA, Carmichael SL, Lu T, Bennett M, Lee HC. Does active treatment in infants born at 22-23 weeks correlate with outcomes of more mature infants at the same hospital? An analysis of California NICU data, 2015-2019 [published online ahead of print, 2022 Mar 31]. J Perinatol. 2022;10.1038/s41372-022-01381-x. doi:10.1038/s41372-022-01381-xRysavy M, Nakamura T, Mehler K, et al. Use of 2.0-mm endotracheal tubes for periviable infants [published online ahead of print, 2022 Jan 26]. J Perinatol. 2022;10.1038/s41372-022-01323-7. doi:10.1038/s41372-022-01323-7
  • Bell EF, Hintz SR, Hansen NI, et al. Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018. JAMA. 2022;327(3):248-263. doi:10.1001/jama.2021.23580
  • Dagle JM, Rysavy MA, Hunter SK, et al. Cardiorespiratory management of infants born at 22 weeks’ gestation: The Iowa approach [published online ahead of print, 2021 Nov 10]. Semin Perinatol. 2021;151545. doi:10.1016/j.semperi.2021.151545
  • Rysavy MA, Li L, Tyson JE, et al. Should Vitamin A Injections to Prevent Bronchopulmonary Dysplasia or Death Be Reserved for High-Risk Infants? Reanalysis of the National Institute of Child Health and Human Development Neonatal Research Network Randomized Trial. J Pediatr. 2021;236:78-85.e5. doi:10.1016/j.jpeds.2021.05.022
  • Rysavy, M.A., Colaizy, T.T., Bann, C.M. et al. The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants. J Perinatol 41, 2270–2278 (2021). https://doi.org/10.1038/s41372-021-00999-7
  • Pavlek LR, Rivera BK, Smith CV, et al. Eligibility Criteria and Representativeness of Randomized Clinical Trials That Include Infants Born Extremely Premature: A Systematic Review. J Pediatr. 2021;235:63-74.e12. doi:10.1016/j.jpeds.2021.04.028
  • Rysavy MA, Bell EF. Neonatal Intensive Care for Very Preterm Infants in China. JAMA Network Open. 2021;4(8):e2118940. Published 2021 Aug 2. doi:10.1001/jamanetworkopen.2021.18940
  • Hoover AC, Segal RS, Zimmerman MB, et al. Urine Trouble: Reducing Midstream Clean Catch Urine Contamination Among Children 3-17 Years Old. Pediatrics. 2021;148(2):e2020049787. doi:10.1542/peds.2020-049787
  • Rysavy MA, Colaizy TT, Bann CM, et al. The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants. J Perinatol. 2021;41(9):2270-2278. doi:10.1038/s41372-021-00999-7
  • Rysavy MA, Mehler K, Oberthür A, et al. An Immature Science: Intensive Care for Infants Born at ≤23 Weeks of Gestation. J Pediatr. 2021;233:16-25.e1. doi:10.1016/j.jpeds.2021.03.006
  • Kono Y, Rysavy MA, Nakanishi H, Kusuda S. Outcomes of infants born at periviable gestations in Japan. Acta Paediatr. 2021;110(5):1694-1695. doi:10.1111/apa.15796
  • Rysavy MA, Haward MF. Providing Neonatal Outcome Estimates as an Intervention. JAMA Pediatr. 2021;175(3):325. doi:10.1001/jamapediatrics.2020.5167
  • Rysavy MA, Horbar JD, Bell EF, et al. Assessment of an Updated Neonatal Research Network Extremely Preterm Birth Outcome Model in the Vermont Oxford Network. JAMA Pediatr. 2020;174(5):e196294. doi:10.1001/jamapediatrics.2019.6294
  • Brumbaugh JE, Bell EF, Grey SF, et al. Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia. J Pediatr. 2020;219:152-159.e5. doi:10.1016/j.jpeds.2019.12.028
  • Rysavy MA, Watkins PL, Colaizy TT, Das A. Is routine evaluation of gastric residuals for premature infants safe or effective?. J Perinatol. 2020;40(3):540-543. doi:10.1038/s41372-019-0582-8
  • Smith A, Rysavy MA, El-Khuffash AF, McNamara PJ. Reply to: Methodological considerations in accuracy and reliability of qualitative echocardiography assessment of right ventricular size and function in neonates. Echocardiography. 2019;36(10):1961-1962. doi:10.1111/echo.14484
  • Rysavy MA, Ehret DEY. Extremely Preterm Birth Outcomes in Sweden. JAMA. 2019;321(12):1163-1164. doi:10.1001/jama.2019.2020
  • Brumbaugh JE, Hansen NI, Bell EF, et al. Outcomes of Extremely Preterm Infants With Birth Weight Less Than 400 g. JAMA Pediatr. 2019;173(5):434-445. doi:10.1001/jamapediatrics.2019.0180
  • Rysavy MA, Bell EF, Iams JD, et al. Discordance in Antenatal Corticosteroid Use and Resuscitation Following Extremely Preterm Birth. J Pediatr. 2019;208:156-162.e5. doi:10.1016/j.jpeds.2018.12.063