Selected Publications
ExPortal and the LiaFSR Regulatory System Coordinate the Response to Cell Membrane Stress in Streptococcus pyogenes
Lin Y, Sanson MA, Vega LA, Shah B, Regmi S, Cubria MB, Flores AR. ExPortal and the LiaFSR Regulatory System Coordinate the Response to Cell Membrane Stress in Streptococcus pyogenes. mBio. 2020 Sep 15;11(5). doi: 10.1128/mBio.01804-20. PubMed PMID: 32934083; PubMed Central PMCID: PMC7492735.
Strain-Dependent Effect of Capsule on Transmission and Persistence in an Infant Mouse Model of Group A Streptococcus Infection
Vega LA, Sanson MA, Shah BJ, Flores AR. Strain-Dependent Effect of Capsule on Transmission and Persistence in an Infant Mouse Model of Group A Streptococcus Infection. Infect Immun. 2020 Mar 23;88(4). doi: 10.1128/IAI.00709-19. Print 2020 Mar 23. PubMed PMID: 32014891; PubMed Central PMCID: PMC7093130.
Unexpected relationships between frequency of antimicrobial resistance, disease phenotype and emm type in group A Streptococcus
Sanson MA, Macias OR, Shah BJ, Hanson B, Vega LA, Alamarat Z, Flores AR. Unexpected relationships between frequency of antimicrobial resistance, disease phenotype and emm type in group A Streptococcus. Microb Genom. 2019 Nov;5(11). doi: 10.1099/mgen.0.000316. PubMed PMID: 31755853; PubMed Central PMCID: PMC6927302.
Clinical Manifestations and Bacterial Genomic Analysis of Group A Streptococcus Strains That Cause Pediatric Toxic Shock Syndrome
Deniskin R, Shah B, Muñoz FM, Flores AR. Clinical Manifestations and Bacterial Genomic Analysis of Group A Streptococcus Strains That Cause Pediatric Toxic Shock Syndrome. J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):265-268. doi: 10.1093/jpids/piy069. PubMed PMID: 30085250; PubMed Central PMCID: PMC6601382.
Capsule-Negative emm Types Are an Increasing Cause of Pediatric Group A Streptococcal Infections at a Large Pediatric Hospital in Texas
Flores AR, Chase McNeil J, Shah B, Van Beneden C, Shelburne SA. Capsule-Negative emm Types Are an Increasing Cause of Pediatric Group A Streptococcal Infections at a Large Pediatric Hospital in Texas. J Pediatric Infect Dis Soc. 2019 Jul 1;8(3):244-250. doi: 10.1093/jpids/piy053. PubMed PMID: 30085121.
Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus
DebRoy S, Li X, Kalia A, Galloway-Pena J, Shah BJ, Fowler VG, Flores AR, Shelburne SA. Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus. Microb Genom. 2018 Nov;4(11). doi: 10.1099/mgen.0.000235. Epub 2018 Nov 9. PubMed PMID: 30412460; PubMed Central PMCID: PMC6321872.
Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes
Flores AR, Olsen RJ, Cantu C, Pallister KB, Guerra FE, Voyich JM, Musser JM. Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes. Infect Immun. 2017 May;85(5). doi: 10.1128/IAI.00949-16. Print 2017 May. PubMed PMID: 28264907; PubMed Central PMCID: PMC5400840.
Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes
Flores AR, Galloway-Peña J, Sahasrabhojane P, Saldaña M, Yao H, Su X, Ajami NJ, Holder ME, Petrosino JF, Thompson E, Margarit Y Ros I, Rosini R, Grandi G, Horstmann N, Teatero S, McGeer A, Fittipaldi N, Rappuoli R, Baker CJ, Shelburne SA. Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6431-6. doi: 10.1073/pnas.1504725112. Epub 2015 May 4. PubMed PMID: 25941374; PubMed Central PMCID: PMC4443349.