Dr. Pritesh Mutha is a board-certified interventional gastroenterologist and associate professor at McGovern Medical School at UTHealth Houston. He is also the Director of the Third Space Endoscopy program for the Center for Interventional Gastroenterology (iGUT) at UTHealth Houston, a comprehensive program focusing on cutting-edge endoscopic management of gastrointestinal diseases.

Dr. Mutha has focused on offering personalized care that is tailored to his patients’ needs throughout his ten years of practice. He takes the time to thoroughly explain every procedure to his patients to enable them to make informed decisions. He uses the latest technology to diagnose and treat various types of gastrointestinal diseases including cancers and performs complex endoscopic procedures. Dr. Mutha is also board certified in lifestyle medicine and supports plant-based nutrition. While providing state-of-the-art treatment to his patients, he also recommends diet and lifestyle changes for potential treatment and prevention of GI diseases. In addition to his clinical experience, he also conducts research. His peer-reviewed research work has been presented at national and international conferences and published in prestigious academic journals

Dr. Mutha specializes in many acute and chronic conditions, such as pancreatitis, pancreatic cysts, pancreatic cancer, other GI cancers, gallstones, bile duct diseases, colon polyps, colon cancer, swallowing disorders, GERD, Barrett’s esophagus, achalasia, gastroparesis, small intestinal diseases, and other digestive disorders. Besides upper endoscopy and colonoscopy, he performs endoscopic ultrasound (EUS), ERCP (endoscopic retrograde cholangiopancreatography), per-oral endoscopic myotomy (POEM), gastric-Per-oral endoscopic myotomy (G-POEM), endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), endoscopic ablation therapy, endoscopic stenting, and endoscopic anti-reflux therapy. Dr. Mutha works closely with the oncology and surgery teams to help with timely diagnosis, staging, and management of gastrointestinal tract cancers.

Following his graduation from the Grant Medical College and Sir J.J. Group of Hospitals in Mumbai, India, Dr. Mutha pursued a master’s degree in Public Health at The University of Texas Health Science Center (UTHealth) and simultaneously conducted research studies at MD Anderson Cancer Center. Dr. Mutha completed his internship and residency in Internal Medicine at the University of Pittsburgh Medical Center (UPMC). His passion for understanding and healing digestive disorders led him to pursue a fellowship in gastroenterology and hepatology at the Virginia Commonwealth University of Health Sciences (VCUHS). He was elected as the chief fellow and then transitioned to a faculty role at VCUHS. Dr. Mutha practiced gastroenterology as an advanced endoscopist and GI motility specialist at the McGuire VA Medical Center and simultaneously trained medical students, residents, and fellows as a teaching faculty at VCU Medical School for 7 years before moving back to Houston, Texas.

Dr. Mutha is an active member of several national and international GI societies such as ASGE, ACG, AGA and the American College of Lifestyle Medicine. He has served as a member of Abstract review committee for ACG.

Dr. Mutha, a Houstonian, and his wife are proud parents of a ten-year-old kid. In his free time, he likes to play cricket and tennis, read, teach, volunteer, and spend time with his family and friends. Additionally, Dr. Mutha is a co-founder of a non-profit organization which aims to help patients conquer stress from within.

LANGUAGE PROFICIENCY: English, Hindi, Marathi, Marwari and Gujarati


Bachelor of Medicine, Bachelor of Science (MBBS)
Grant Medical College and Sir JJ Group of Hospital, Maharashtra University of Health Sciences, India
Masters in Public Health – MPH (Epidemiology)
University of Texas Health Science Center at Houston, Texas
Residency in Internal Medicine (ABIM)
University of Pittsburgh Medical Center Presbyterian, Pittsburgh, Pennsylvania
Fellowship in Gastroenterology (ABIM-GI)
Virginia Commonwealth University of Health Sciences, Richmond, Virginia

Areas of Interest

Clinical Interests

Areas of Interest:

  • Pancreas related disorders – pancreatitis, cysts, cancers, etc
  • Bile duct: gallstones, cancers, stenosis of sphincter, biliary strictures, obstructive jaundice etc
  • Esophagus: GERD, dysphagia, achalasia, cancers, strictures, Barrett’s, GI bleeding, etc
  • Stomach: Gastroparesis, gastric intestinal metaplasia, gastric polyps, cancers, gastritis, ulcers, GI bleeding, etc
  • Small intestine: celiac disease, small intestinal bacterial overgrowth, ulcers, cancers, GI bleeding, etc
  • Colon: Screening and follow up colonoscopy, diverticulosis, diarrhea, constipation, GI bleeding, etc

Performs the following procedures:

  • Diagnostic and therapeutic upper endoscopy and colonoscopy
  • Diagnostic and therapeutic endoscopic ultrasound (EUS)
  • Endoscopic retrograde cholangiopancreaticography (ERCP)
  • Endoluminal stenting
  • Endoscopic suturing of Fistulas
  • Third space endoscopy (EMR, ESD, POEM, G-POEM, Z-POEM, D-POEM)
  • Push Enteroscopy
  • Double balloon enteroscopy
  • Capsule endoscopy
  • Esophageal and anorectal manometry
  • pH and impedance studies

Research Interests

Dr. Mutha’s research focuses on Esophageal disorders, pancreatobiliary diseases, and application of innovative endoscopic technologies in diagnosis and management of various gastrointestinal diseases.