STICU Ventilator Weaning and Extubation Protocol


Original Date: 04/2003 | Supersedes: 11/2013, 06/2016 | Last Review Date: 04/2021
Purpose: To safely wean and extubate injured patients.


Ready to Wean Assessment

  • The following clinical criteria must be met:
    • Hemodynamically stable (Not actively titrating)
    • Not receiving paralytics
    • Stable arrhythmia
    • Not on ICP Protocol
    • Acute Neurological events > 24hrs
    • Not on hypothermia protocol
    • Not on ECMO
    • Not Chronic Ventilator Dependence
  • Above assessment can be overridden by Critical care Attending

SIMV Weaning

  • Ventilator weaning can start on all patients when patient is over breathing the ventilator. Respiratory therapist can wean rate, FiO2, and Pressure Support. All other settings should be discussed with MD and orders placed in computer.

Spontaneous Breathing Trial Assessment

  • FiO2 <50%
  • PEEP ≤ 8 cm H20
  • pH (> 7.32)
  • RR (8 – 35 bpm)
  • HR < 130 bpm, MAP > 60 mm Hg and requiring < 5 μg/min norepinephrine or equivalent
  • Hgb (> 7 gm/dL)
  • Able to breathe spontaneously
  • Not chemically paralyzed
  • Improvement or resolution of the indication for ventilation
  • Arousability, Richmond Agitation Sedation Scale (RASS) > -2) and ability to cough.
    • RASS score will be documented by the day shift nurse in the am daily

If answered YES to all above, Respiratory Therapy will coordinate a sedation holiday with nursing and perform Spontaneous Breathing Trial (SBT).

SIMV Weaning

  • Ventilator weaning can start on all patients when patient is over breathing the ventilator. Respiratory Therapist can wean rate, FiO2, and Pressure Support. All other settings should be discussed with MD and orders placed in computer.

Spontaneous Breathing Trial (SBT)

  • Initiate SBT; ventilator settings:
    • PSV 5 cm H20 or PSV 0 with Automatic Airway Compensation or equivalent
    • Peep ≤ 8 cmH20
    • FIO2 ≤ 50%
    • Duration of trial 30 minutes
    • Respiratory Therapist must remain at the bedside for the 1st 5-10 minutes of the trial to observe patient tolerance, and appropriateness to continue; then remain in the unit thereafter for the duration of the trial

After trial has been passed and completed, attempt mechanics and extubation criteria. Notify STICU Fellow or Attending if patient is ready to extubate.

Extubation Criteria

  • Secretions (Moderate or less secretions)
  • Oxygenation (SaO2 >92% on 50% FiO2 or less)
  • Airway / alert (Patient able to protect airway)
  • Parameters (Pulmonary Mechanics)
    • RR < 30
    • VT > 5 cc/kg
    • Minute ventilation < 12 LPM
    • NIF < – 20 cm H2O
    • Vital Capacity >15cc/kg/IBW
    • RSBI < 105
    • Cuff leak present when cuff deflated

(Endotracheal tube cuff leak must be verified by a physician before extubation is attempted).

Weaning Intolerance Criteria

  • RR > 35 bpm
  • SaO2 < 88%
  • HR > 140
  • MAP >120 or < 60 mm Hg
  • Acute change in mental status
  • New arrhythmia occurs

Should the above “fail” criteria be demonstrated, the SBT shall be stopped, PS increased to a comfortable level (non fatiguing level of support) that maintains a VT of > 5 ml/kg and a RR of < 35 bpm and the physician will be informed.


References:

  • Timothy D Girard, John P Kress, Barry D Fuchs, Jason W W Thomason, William D Schweickert, Brenda T Pun, Darren B Taichman, Jan G Dunn,. (2008). Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled tri. Lancet. 371, 126-134.
  • Tanios, MA, et al. A randomized, controlled trial of the role of weaning predictors in clinical decision-making. Critical Care Medicine. 2006; 34(10). 2676-7
  • Cohen, JD et al. Extubation outcome following a spontaneous breathing trial with automatic tube compensation versus continuous positive airway pressure. Critical Care Medicine. 2006 ; 34(3) 682-6
  • Haberthur, C. et al. Extubation after breathing trials with automatic tube compensation, T-tube or pressure support ventilation. Acta Anesthesiology Scanda. 2002 46(8) 973-9
  • Perren, A. et al. Protocol-directed weaning from mechanical ventilation: clinical outcome in patients randomized for a 30 min or 120 min trial with pressure support ventilation. Intensive Care Medicine. 2002 28(8). 1058-63.
  • MacIntyre, N. et al. Evidence-based guidelines for weaning and discontinuing ventilatory support. Chest 120(6) 2001 375s-95s.
  • Marelich, GP et al. Protocol weaning of mechanical ventilation in medical and surgical patients by respiratory care practitioners and nurses. Chest 2000 118 459-67.
  • Esteban, A. et al. Effect of spontaneous breathing trial duration on outcome of attempts to discontinue mechanical ventilation: the Spanish Lung Failure Group. Am J Respiratory Crit Care Med 1999; 159: 512-18
  • Kollef, MH. Et al. A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. Critical Care Medicine. 1997 25; 567-74
  • Estaban, A et al. Extubation outcome after spontaneous breathing trials with t-tube or pressure support ventilation. The Spanish Lung Failure Collaboration Group. Am J Respir Crit Care. 1997 156; 459-65
  • Ely, WE, et al. Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N. Eng J Med 1996; 335; 1864-69
  • Estaban, A, et al. A comparison of four methods of weaning patients from mechanical ventilation: The Spanish Lung Failure Collaborative Group. N Eng J Med. 1995; 332; 345-50
  • Brochard, L. et al. Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation. Am J Respir Crit Care Med 1994; 150; 896-903.