Research sheds light on oxygen treatment for cardiovascular diseases

By Darla Brown, Office of Communications
June 23, 2023

Collaborative research from two McGovern Medical School departments on the role of oxygen in cardiovascular disease treatment recently was published in Nature Reviews Cardiology (Impact Factor 49.4).

Basic scientists and clinicians from the departments of Anesthesiology, Critical Care and Pain Medicine and Internal Medicine reviewed multiple randomized controlled trials on the use of oxygen and cardiac injury to produce “Interplay of Hypoxia-Inducible Factors and Oxygen Therapy in Cardiovascular Medicine.”

Based on their review of recent large clinical trials on oxygen therapy during myocardial ischemia, cardiac arrest, heart failure, and cardiac surgery, the authors found that oxygen therapy does not have a universally safe dose range for different cardiovascular diseases.

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