Gene Ontology Comparison Results

Description of the problem:
Number of classes: 2
Number of genes: 6799
Number of genes that passed filtering criteria: 6799
Number of investigated GO categories: 1231
Random variance model was not used because distribution assumptions of this model were not satisfied

GO categories which discriminate among classes:

Table – Sorted by p-value of the LS permutation test.
The first 15 GO categories are significant at the nominal 0.01 level of the LS permutation test or KS permutation test

GO category GO description Number of genes LS Permutation p-value KS Permutation p-value
1 0019992 diacylglycerol binding 11 0.00095 0.00018
2 0030532 small nuclear ribonucleoprotein complex 6 0.00111 0.0099
3 0016208 AMP binding 6 0.00496 0.12196
4 0015300 solute\:solute antiporter activity 6 0.00515 0.05095
5 0009072 aromatic amino acid family metabolism 7 0.00621 0.4628
6 0046148 pigment biosynthesis 7 0.00651 0.34548
7 0000160 two-component signal transduction system (phosphorelay) 5 0.00953 0.15316
8 0016779 nucleotidyltransferase activity 42 0.02063 0.00723
9 0051325 interphase 43 0.0393 0.00019
10 0051329 interphase of mitotic cell cycle 43 0.0393 0.00019
11 0000080 G1 phase of mitotic cell cycle 9 0.04143 0.00563
12 0051318 G1 phase 9 0.04143 0.00563
13 0019199 transmembrane receptor protein kinase activity 31 0.06295 0.00289
14 0000082 G1/S transition of mitotic cell cycle 29 0.08562 0.00556
15 0030934 anchoring collagen 5 0.14383 0.00528

Table Significant GO categories consist of the following genes:

GO category GO description Description Qiagen ID GB acc UG cluster Gene symbol Geometric mean of ratios ( Disease / Normal ) p-value
1 0019992 diacylglycerol binding V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 85181 RAF1 1.243 0.33932
2 0019992 diacylglycerol binding Rho/rac guanine nucleotide exchange factor (GEF) 2 H003985_01 AB014551 155120 ARHGEF2 1.355 0.10846
3 0019992 diacylglycerol binding Protein kinase D2 H005622_01 AF151021 91146 PKD2 0.803 0.46456
4 0019992 diacylglycerol binding Ras association (RalGDS/AF-6) domain family 1 H008796_01 AF061836 26931 RASSF1 1.706 0.07124
5 0019992 diacylglycerol binding Chimerin (chimaerin) 1 H011078_01 X51408 169965 CHN1 2.371 0.00707
6 0019992 diacylglycerol binding Cholinephosphotransferase 1 H014496_01 NM_020244 171889 LOC56994 0.734 0.14947
7 0019992 diacylglycerol binding Rho-associated, coiled-coil containing protein kinase 2 H001360_01 NM_004850 58617 ROCK2 0.841 0.22988
8 0019992 diacylglycerol binding Protein kinase C, gamma H001596_01 Z15114 2890 PRKCG 1.216 0.31059
9 0019992 diacylglycerol binding Diacylglycerol kinase, alpha (80kD) H001620_01 X62535 172690 DGKA 0.721 0.27692
10 0019992 diacylglycerol binding Protein kinase C, iota H001676_01 L33881 1904 PRKCI 0.627 0.09671
11 0019992 diacylglycerol binding Diacylglycerol kinase, zeta (104kD) H001680_01 U94905 89981 DGKZ 0.633 0.12362
12 0030532 small nuclear ribonucleoprotein complex DKFZP434D174 protein H006736_01 AL080150 302421 DKFZP434D174 0.646 0.01071
13 0030532 small nuclear ribonucleoprotein complex U6 snRNA-associated Sm-like protein H006779_01 NM_012321 76719 LSM4 1.217 0.34087
14 0030532 small nuclear ribonucleoprotein complex Small nuclear ribonucleoprotein polypeptide A' H007604_01 X13482 80506 SNRPA1 0.764 0.08756
15 0030532 small nuclear ribonucleoprotein complex Gemin4 H008741_01 AF173856 19614 GEMIN4 0.505 0.02841
16 0030532 small nuclear ribonucleoprotein complex U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p H009322_01 AB007510 181368 PRP8 0.961 0.74755
17 0030532 small nuclear ribonucleoprotein complex Nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs) H009404_01 AJ276003 69851 NOLA1 0.551 0.02424
18 0016208 AMP binding Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 183037 PRKAR1A 1.244 0.00681
19 0016208 AMP binding Rap1 guanine-nucleotide-exchange factor directly activated by cAMP H008675_01 U78168 8578 EPAC 1.035 0.81688
20 0016208 AMP binding Cyclic nucleotide gated channel beta 1 H009827_01 AF042498 93909 CNGB1 0.885 0.16333
21 0016208 AMP binding Acetyl-CoA synthetase H009930_01 AK000188 14779 LOC55902 0.554 0.01774
22 0016208 AMP binding Hyperpolarization activated cyclic nucleotide-gated potassium channel 2 H010769_01 AJ012582 124161 HCN2 1.202 0.44732
23 0016208 AMP binding KIAA1535 protein H015256_01 AB040968 284171 KIAA1535 1.282 0.29396
24 0015300 solute\:solute antiporter activity Solute carrier family 22 (organic cation transporter), member 1-like H001870_01 AF030302 50868 SLC22A1L 0.783 0.37607
25 0015300 solute\:solute antiporter activity Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 H004295_01 AB026891 6682 SLC7A11 1.331 0.00413
26 0015300 solute\:solute antiporter activity Solute carrier family 9 (sodium/hydrogen exchanger), isoform 5 H006240_01 AF111173 198295 SLC9A5 1.356 0.31776
27 0015300 solute\:solute antiporter activity Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 H006923_01 J03592 164280 SLC25A6 0.969 0.84669
28 0015300 solute\:solute antiporter activity Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 H008432_01 AF070548 184877 SLC25A11 1.17 0.36497
29 0015300 solute\:solute antiporter activity Solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride H001053_01 S68616 170222 SLC9A1 1.615 0.01454
30 0009072 aromatic amino acid family metabolism Tyrosine hydroxylase H002673_01 M17589 178237 TH 1.055 0.8706
31 0009072 aromatic amino acid family metabolism Tyrosinase (oculocutaneous albinism IA) H003362_01 M27160 2053 TYR 3.308 1e-04
32 0009072 aromatic amino acid family metabolism Silver (mouse homolog) like H003494_01 M77348 95972 SILV 0.864 0.67214
33 0009072 aromatic amino acid family metabolism Kynureninase (L-kynurenine hydrolase) H005832_01 U57721 169139 KYNU 0.771 0.36427
34 0009072 aromatic amino acid family metabolism Fumarylacetoacetate H000004_01 M55150 73875 FAH 1.093 0.81499
35 0009072 aromatic amino acid family metabolism Quinoid dihydropteridine reductase H001542_01 M16447 75438 QDPR 1.296 0.28212
36 0009072 aromatic amino acid family metabolism Phenylalanine hydroxylase H001632_01 U49897 1870 PAH 0.51 0.12984
37 0046148 pigment biosynthesis Tyrosinase (oculocutaneous albinism IA) H003362_01 M27160 2053 TYR 3.308 1e-04
38 0046148 pigment biosynthesis Silver (mouse homolog) like H003494_01 M77348 95972 SILV 0.864 0.67214
39 0046148 pigment biosynthesis Ferrochelatase (protoporphyria) H005094_01 D00726 26 FECH 0.67 0.18109
40 0046148 pigment biosynthesis Uroporphyrinogen III synthase (congenital erythropoietic porphyria) H000636_01 J03824 75593 UROS 1.487 0.12987
41 0046148 pigment biosynthesis Aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) H008422_01 X60364 323383 ALAS2 1.085 0.87138
42 0046148 pigment biosynthesis Uroporphyrinogen decarboxylase H009835_01 AF104421 78601 UROD 0.971 0.75631
43 0046148 pigment biosynthesis Aminolevulinate, delta-, synthase 1 H001696_01 Y00451 78712 ALAS1 1.093 0.65249
44 0000160 two-component signal transduction system (phosphorelay) Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 431 BMI1 0.857 0.38405
45 0000160 two-component signal transduction system (phosphorelay) BUP protein H008754_01 NM_012071 35660 BUP 1.524 0.00307
46 0000160 two-component signal transduction system (phosphorelay) MMS19 (MET18 S. cerevisiae)-like H011462_01 AF007151 288891 MMS19L 0.759 0.40935
47 0000160 two-component signal transduction system (phosphorelay) Hypothetical protein FLJ23132 H015444_01 NM_025054 287727 FLJ23132 0.933 0.62566
48 0000160 two-component signal transduction system (phosphorelay) Homo sapiens mRNA; cDNA DKFZp564I172 (from clone DKFZp564I172); complete CDS H015715_01 AL136635 300816 0.726 0.08272
49 0016779 nucleotidyltransferase activity Unactive progesterone receptor, 23 kD H001846_01 L24804 278270 P23 1.03 0.89309
50 0016779 nucleotidyltransferase activity 3'-phosphoadenosine 5'-phosphosulfate synthase 1 H001876_01 AF105227 3833 PAPSS1 1.307 0.26494
51 0016779 nucleotidyltransferase activity Polymerase (DNA directed), gamma H001903_01 X98093 80961 POLG 1.118 0.59162
52 0016779 nucleotidyltransferase activity 2'-5'oligoadenylate synthetase 2 H001966_01 M87284 264981 OAS2 0.744 0.50026
53 0016779 nucleotidyltransferase activity UDP-glucose pyrophosphorylase 2 H002258_01 U27460 77837 UGP2 1.189 0.63283
54 0016779 nucleotidyltransferase activity Proliferating cell nuclear antigen H002599_01 M15796 78996 PCNA 0.875 0.66117
55 0016779 nucleotidyltransferase activity Telomerase reverse transcriptase H002699_01 AF015950 115256 TERT 0.937 0.62951
56 0016779 nucleotidyltransferase activity Polymerase (DNA directed), beta H002879_01 D29013 180107 POLB 1.092 0.77827
57 0016779 nucleotidyltransferase activity Polymerase (DNA directed), alpha H003792_01 X06745 267289 POLA 0.935 0.80067
58 0016779 nucleotidyltransferase activity Galactose-1-phosphate uridylyltransferase H003947_01 M60091 75641 GALT 1.672 0.12632
59 0016779 nucleotidyltransferase activity Topoisomerase-related function protein 4-1 H004233_01 AB005754 225951 TRF4 1.363 0.42912
60 0016779 nucleotidyltransferase activity UDP-N-acetylglucosamine pyrophosphorylase 1 H004589_01 AB011004 21293 UAP1 1.379 0.22684
61 0016779 nucleotidyltransferase activity Pericentriolar material 1 H004678_01 L27841 75737 PCM1 0.719 0.17315
62 0016779 nucleotidyltransferase activity Phosphate cytidylyltransferase 1, choline, beta isoform H004782_01 AF052510 132794 PCYT1B 1.064 0.27452
63 0016779 nucleotidyltransferase activity Polymerase (RNA) III (DNA directed) (62kD) H004821_01 U93867 250745 RPC62 1.378 0.12697
64 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide B (140kD) H005570_01 X63563 296014 POLR2B 0.429 0.00651
65 0016779 nucleotidyltransferase activity Ubiquitin specific protease 14 (tRNA-guanine transglycosylase) H006332_01 U30888 75981 USP14 0.898 0.65472
66 0016779 nucleotidyltransferase activity Nucleotide binding protein H006333_01 U18919 296422 NBP 1.374 0.13261
67 0016779 nucleotidyltransferase activity Poly(A) polymerase alpha H006445_01 X76770 49007 PAPOLA 1.457 0.0877
68 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide H H006451_01 U37689 3128 POLR2H 1.246 0.1232
69 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) H006464_01 U37690 71618 POLR2L 0.652 0.18083
70 0016779 nucleotidyltransferase activity Telomerase-associated protein 1 H006594_01 U86136 232070 TEP1 0.966 0.82723
71 0016779 nucleotidyltransferase activity Polymerase (DNA-directed), mu H006716_01 AJ131891 46964 POLM 0.575 0.32178
72 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) H007101_01 L37127 80475 POLR2J 0.765 0.1425
73 0016779 nucleotidyltransferase activity Hypothetical protein FLJ10509 H007616_01 AK001371 274319 FLJ10509 1.587 0.10474
74 0016779 nucleotidyltransferase activity Similar to DNA-directed RNA polymerase I (135 kDa) H007868_01 AK001678 86337 FLJ10816 0.838 0.24108
75 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) H007908_01 Z47727 150675 POLR2K 0.891 0.67863
76 0016779 nucleotidyltransferase activity N-acetylneuraminic acid phosphate synthase; sialic acid synthase H008206_01 AK001659 274424 SAS 0.779 0.36438
77 0016779 nucleotidyltransferase activity Polymerase (DNA directed), gamma 2, accessory subunit H008428_01 U94703 30541 POLG2 1.327 0.0338
78 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide A (220kD) H008768_01 X63564 171880 POLR2A 1.279 0.41871
79 0016779 nucleotidyltransferase activity Polymerase (DNA directed), delta 2, regulatory subunit (50kD) H000074_01 U21090 74598 POLD2 1.102 0.70683
80 0016779 nucleotidyltransferase activity Histone fold protein CHRAC17; DNA polymerase epsilon p17 subunit H010753_01 AF070640 108112 CHRAC17 0.616 0.1856
81 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide E (25kD) H010908_01 D38251 24301 POLR2E 0.821 0.37832
82 0016779 nucleotidyltransferase activity Transcriptional coactivator H011559_01 AF047002 241520 ALY 0.756 0.17392
83 0016779 nucleotidyltransferase activity Dyskeratosis congenita 1, dyskerin H012214_01 AF067008 4747 DKC1 1.49 0.14225
84 0016779 nucleotidyltransferase activity Phosphate cytidylyltransferase 2, ethanolamine H012323_01 D84307 226377 PCYT2 0.542 0.17937
85 0016779 nucleotidyltransferase activity BN51 (BHK21) temperature sensitivity complementing H013188_01 M17754 1276 BN51T 0.987 0.96033
86 0016779 nucleotidyltransferase activity CMP-N-acetylneuraminic acid synthase H014153_01 NM_018686 12492 LOC55907 0.962 0.89372
87 0016779 nucleotidyltransferase activity DNA polymerase epsilon p12 subunit H014636_01 NM_019896 19980 P12 0.666 0.17962
88 0016779 nucleotidyltransferase activity Hypothetical protein FLJ13390 similar to PAF53 H014829_01 NM_022490 24884 FLJ13390 0.988 0.97023
89 0016779 nucleotidyltransferase activity Polymerase (RNA) II (DNA directed) polypeptide I (14.5kD) H016370_01 NM_006233 47062 POLR2I 1.137 0.4602
90 0016779 nucleotidyltransferase activity X-ray repair complementing defective repair in Chinese hamster cells 3 H000124_01 AF035586 99742 XRCC3 1.422 0.23269
91 0051325 interphase Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 82932 CCND1 1.251 0.36936
92 0051325 interphase Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A 0.838 0.33129
93 0051325 interphase Cell division cycle 34 H002232_01 L22005 76932 CDC34 1.415 0.21701
94 0051325 interphase Cyclin E1 H002323_01 M74093 9700 CCNE1 1.288 0.47974
95 0051325 interphase Cyclin B1 H002371_01 M25753 23960 CCNB1 0.675 0.15891
96 0051325 interphase Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 1.853 0.11588
97 0051325 interphase Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) H002606_01 L20320 184298 CDK7 1.055 0.83498
98 0051325 interphase Menage a trois 1 (CAK assembly factor) H000312_01 X87843 82380 MNAT1 0.689 0.32732
99 0051325 interphase Cyclin A2 H002740_01 X51688 85137 CCNA2 1.344 0.24008
100 0051325 interphase Cyclin G1 H002889_01 X77794 79101 CCNG1 0.613 0.00464
101 0051325 interphase Cell division cycle 25C H003048_01 M34065 656 CDC25C 0.762 0.17709
102 0051325 interphase CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 69563 CDC6 1.021 0.86789
103 0051325 interphase V-abl Abelson murine leukemia viral oncogene homolog 1 H003207_01 NM_005157 146355 ABL1 1.038 0.88522
104 0051325 interphase General transcription factor IIH, polypeptide 1 (62kD subunit) H003500_01 M95809 89578 GTF2H1 1.304 0.40518
105 0051325 interphase Cullin 2 H000387_01 U83410 82919 CUL2 1.456 0.24367
106 0051325 interphase Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 106070 CDKN1C 1.211 0.40117
107 0051325 interphase Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 184572 CDC2 0.503 0.10961
108 0051325 interphase Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) H003750_01 AF004819 72901 CDKN2B 1.264 0.44457
109 0051325 interphase Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 29656 CDKN2D 0.909 0.73706
110 0051325 interphase Chromosome condensation 1 H000401_01 X12654 84746 CHC1 0.789 0.22395
111 0051325 interphase Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) H004513_01 U28386 159557 KPNA2 0.832 0.76185
112 0051325 interphase Cell cycle progression 2 protein H000462_01 AF011792 170980 CPR2 0.794 0.28286
113 0051325 interphase CDC28 protein kinase 2 H000463_01 X54942 83758 CKS2 0.849 0.4051
114 0051325 interphase Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 180059 1.389 0.13754
115 0051325 interphase RNA, U17D small nucleolar H005580_01 AJ006835 196769 RNU17D 1.352 0.3504
116 0051325 interphase DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 21189 DNAJA2 1.364 0.12707
117 0051325 interphase Cullin 4A H006657_01 U58090 183874 CUL4A 0.602 0.37343
118 0051325 interphase Cyclin-E binding protein 1 H007016_01 AB027289 26663 LOC51191 1.057 0.91297
119 0051325 interphase Deleted in oral cancer (mouse, homolog) 1 H000606_01 AF006484 3436 DOC1 0.941 0.64521
120 0051325 interphase G1 to S phase transition 1 H000607_01 X17644 2707 GSPT1 1.06 0.69634
121 0051325 interphase DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H007565_01 U75967 27424 DDX11 0.658 0.23892
122 0051325 interphase Cullin 5 H008068_01 X81882 101299 CUL5 0.892 0.48091
123 0051325 interphase Cullin 1 H008496_01 AF062536 14541 CUL1 0.824 0.17857
124 0051325 interphase Protein phosphatase 6, catalytic subunit H008575_01 X92972 279563 PPP6C 0.688 0.19804
125 0051325 interphase Branched chain aminotransferase 1, cytosolic H008589_01 U21551 157205 BCAT1 1.516 0.15679
126 0051325 interphase GAP-associated tyrosine phosphoprotein p62 (Sam68) H009232_01 M88108 119537 SAM68 0.663 0.15228
127 0051325 interphase DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H009291_01 U75968 27424 DDX11 0.811 0.38746
128 0051325 interphase Cdk inhibitor p21 binding protein H010584_01 AB040450 279862 TOK-1 0.875 0.63115
129 0051325 interphase Anaphase-promoting complex subunit 5 H010633_01 NM_016237 7101 APC5 1.211 0.40229
130 0051325 interphase Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 283948 0.858 0.22618
131 0051325 interphase Cyclin T2 H001491_01 AF048731 155478 CCNT2 0.884 0.75297
132 0051325 interphase Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) H001670_01 L25876 84113 CDKN3 0.581 0.10101
133 0051325 interphase Dynamin 2 H001738_01 L36983 167013 DNM2 1.065 0.74997
134 0051329 interphase of mitotic cell cycle Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 82932 CCND1 1.251 0.36936
135 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A 0.838 0.33129
136 0051329 interphase of mitotic cell cycle Cell division cycle 34 H002232_01 L22005 76932 CDC34 1.415 0.21701
137 0051329 interphase of mitotic cell cycle Cyclin E1 H002323_01 M74093 9700 CCNE1 1.288 0.47974
138 0051329 interphase of mitotic cell cycle Cyclin B1 H002371_01 M25753 23960 CCNB1 0.675 0.15891
139 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 1.853 0.11588
140 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) H002606_01 L20320 184298 CDK7 1.055 0.83498
141 0051329 interphase of mitotic cell cycle Menage a trois 1 (CAK assembly factor) H000312_01 X87843 82380 MNAT1 0.689 0.32732
142 0051329 interphase of mitotic cell cycle Cyclin A2 H002740_01 X51688 85137 CCNA2 1.344 0.24008
143 0051329 interphase of mitotic cell cycle Cyclin G1 H002889_01 X77794 79101 CCNG1 0.613 0.00464
144 0051329 interphase of mitotic cell cycle Cell division cycle 25C H003048_01 M34065 656 CDC25C 0.762 0.17709
145 0051329 interphase of mitotic cell cycle CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 69563 CDC6 1.021 0.86789
146 0051329 interphase of mitotic cell cycle V-abl Abelson murine leukemia viral oncogene homolog 1 H003207_01 NM_005157 146355 ABL1 1.038 0.88522
147 0051329 interphase of mitotic cell cycle General transcription factor IIH, polypeptide 1 (62kD subunit) H003500_01 M95809 89578 GTF2H1 1.304 0.40518
148 0051329 interphase of mitotic cell cycle Cullin 2 H000387_01 U83410 82919 CUL2 1.456 0.24367
149 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 106070 CDKN1C 1.211 0.40117
150 0051329 interphase of mitotic cell cycle Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 184572 CDC2 0.503 0.10961
151 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) H003750_01 AF004819 72901 CDKN2B 1.264 0.44457
152 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 29656 CDKN2D 0.909 0.73706
153 0051329 interphase of mitotic cell cycle Chromosome condensation 1 H000401_01 X12654 84746 CHC1 0.789 0.22395
154 0051329 interphase of mitotic cell cycle Karyopherin alpha 2 (RAG cohort 1, importin alpha 1) H004513_01 U28386 159557 KPNA2 0.832 0.76185
155 0051329 interphase of mitotic cell cycle Cell cycle progression 2 protein H000462_01 AF011792 170980 CPR2 0.794 0.28286
156 0051329 interphase of mitotic cell cycle CDC28 protein kinase 2 H000463_01 X54942 83758 CKS2 0.849 0.4051
157 0051329 interphase of mitotic cell cycle Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 180059 1.389 0.13754
158 0051329 interphase of mitotic cell cycle RNA, U17D small nucleolar H005580_01 AJ006835 196769 RNU17D 1.352 0.3504
159 0051329 interphase of mitotic cell cycle DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 21189 DNAJA2 1.364 0.12707
160 0051329 interphase of mitotic cell cycle Cullin 4A H006657_01 U58090 183874 CUL4A 0.602 0.37343
161 0051329 interphase of mitotic cell cycle Cyclin-E binding protein 1 H007016_01 AB027289 26663 LOC51191 1.057 0.91297
162 0051329 interphase of mitotic cell cycle Deleted in oral cancer (mouse, homolog) 1 H000606_01 AF006484 3436 DOC1 0.941 0.64521
163 0051329 interphase of mitotic cell cycle G1 to S phase transition 1 H000607_01 X17644 2707 GSPT1 1.06 0.69634
164 0051329 interphase of mitotic cell cycle DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H007565_01 U75967 27424 DDX11 0.658 0.23892
165 0051329 interphase of mitotic cell cycle Cullin 5 H008068_01 X81882 101299 CUL5 0.892 0.48091
166 0051329 interphase of mitotic cell cycle Cullin 1 H008496_01 AF062536 14541 CUL1 0.824 0.17857
167 0051329 interphase of mitotic cell cycle Protein phosphatase 6, catalytic subunit H008575_01 X92972 279563 PPP6C 0.688 0.19804
168 0051329 interphase of mitotic cell cycle Branched chain aminotransferase 1, cytosolic H008589_01 U21551 157205 BCAT1 1.516 0.15679
169 0051329 interphase of mitotic cell cycle GAP-associated tyrosine phosphoprotein p62 (Sam68) H009232_01 M88108 119537 SAM68 0.663 0.15228
170 0051329 interphase of mitotic cell cycle DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S. cerevisiae CHL1-like helicase) H009291_01 U75968 27424 DDX11 0.811 0.38746
171 0051329 interphase of mitotic cell cycle Cdk inhibitor p21 binding protein H010584_01 AB040450 279862 TOK-1 0.875 0.63115
172 0051329 interphase of mitotic cell cycle Anaphase-promoting complex subunit 5 H010633_01 NM_016237 7101 APC5 1.211 0.40229
173 0051329 interphase of mitotic cell cycle Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 283948 0.858 0.22618
174 0051329 interphase of mitotic cell cycle Cyclin T2 H001491_01 AF048731 155478 CCNT2 0.884 0.75297
175 0051329 interphase of mitotic cell cycle Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) H001670_01 L25876 84113 CDKN3 0.581 0.10101
176 0051329 interphase of mitotic cell cycle Dynamin 2 H001738_01 L36983 167013 DNM2 1.065 0.74997
177 0000080 G1 phase of mitotic cell cycle Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 1.853 0.11588
178 0000080 G1 phase of mitotic cell cycle Cell division cycle 25C H003048_01 M34065 656 CDC25C 0.762 0.17709
179 0000080 G1 phase of mitotic cell cycle CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 69563 CDC6 1.021 0.86789
180 0000080 G1 phase of mitotic cell cycle Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 106070 CDKN1C 1.211 0.40117
181 0000080 G1 phase of mitotic cell cycle Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 184572 CDC2 0.503 0.10961
182 0000080 G1 phase of mitotic cell cycle Cell cycle progression 2 protein H000462_01 AF011792 170980 CPR2 0.794 0.28286
183 0000080 G1 phase of mitotic cell cycle Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 180059 1.389 0.13754
184 0000080 G1 phase of mitotic cell cycle DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 21189 DNAJA2 1.364 0.12707
185 0000080 G1 phase of mitotic cell cycle Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 283948 0.858 0.22618
186 0051318 G1 phase Cyclin-dependent kinase 2 H002412_01 M68520 19192 CDK2 1.853 0.11588
187 0051318 G1 phase Cell division cycle 25C H003048_01 M34065 656 CDC25C 0.762 0.17709
188 0051318 G1 phase CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 69563 CDC6 1.021 0.86789
189 0051318 G1 phase Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 106070 CDKN1C 1.211 0.40117
190 0051318 G1 phase Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 184572 CDC2 0.503 0.10961
191 0051318 G1 phase Cell cycle progression 2 protein H000462_01 AF011792 170980 CPR2 0.794 0.28286
192 0051318 G1 phase Homo sapiens cDNA FLJ20653 fis, clone KAT01739 H005436_01 AK000660 180059 1.389 0.13754
193 0051318 G1 phase DnaJ (Hsp40) homolog, subfamily A, member 2 H006052_01 AF011793 21189 DNAJA2 1.364 0.12707
194 0051318 G1 phase Homo sapiens ING1-like tumor suppressor protein mRNA, complete CDS H015232_01 AF149724 283948 0.858 0.22618
195 0019199 transmembrane receptor protein kinase activity Discoidin domain receptor family, member 2 H001908_01 X74764 71891 DDR2 0.831 0.53593
196 0019199 transmembrane receptor protein kinase activity V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 H002029_01 M34309 199067 ERBB3 1.307 0.48426
197 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) H002119_01 X66945 748 FGFR1 0.861 0.34712
198 0019199 transmembrane receptor protein kinase activity Ret proto-oncogene (multiple endocrine neoplasia MEN2A, MEN2B and medullary thyroid carcinoma 1, Hir H002140_01 X12949 287270 RET 0.828 0.65442
199 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, H002197_01 M87770 278581 FGFR2 1.129 0.68541
200 0019199 transmembrane receptor protein kinase activity Neurotrophic tyrosine kinase, receptor, type 1 H002234_01 M23102 85844 NTRK1 0.765 0.17994
201 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) H002448_01 M64347 1420 FGFR3 1.597 0.05694
202 0019199 transmembrane receptor protein kinase activity Fms-related tyrosine kinase 4 H002485_01 X69878 74049 FLT4 0.756 0.37366
203 0019199 transmembrane receptor protein kinase activity Activin A receptor, type IIB H002488_01 X77533 23994 ACVR2B 0.642 0.03331
204 0019199 transmembrane receptor protein kinase activity EphA1 H002568_01 M18391 89839 EPHA1 0.961 0.83855
205 0019199 transmembrane receptor protein kinase activity Kinase insert domain receptor (a type III receptor tyrosine kinase) H002712_01 AF035121 12337 KDR 0.74 0.11432
206 0019199 transmembrane receptor protein kinase activity Fibroblast growth factor receptor 4 H002756_01 L03840 165950 FGFR4 0.649 0.23236
207 0019199 transmembrane receptor protein kinase activity Platelet-derived growth factor receptor, alpha polypeptide H002775_01 M21574 74615 PDGFRA 1.096 0.25256
208 0019199 transmembrane receptor protein kinase activity Ret finger protein H000323_01 J03407 142653 RFP 0.784 0.31172
209 0019199 transmembrane receptor protein kinase activity Macrophage stimulating 1 receptor (c-met-related tyrosine kinase) H002936_01 X70040 2942 MST1R 1.543 0.12996
210 0019199 transmembrane receptor protein kinase activity Discoidin domain receptor family, member 1 H002955_01 NM_013994 75562 DDR1 0.792 0.55617
211 0019199 transmembrane receptor protein kinase activity Insulin-like growth factor 2 receptor H003016_01 Y00285 76473 IGF2R 0.813 0.33053
212 0019199 transmembrane receptor protein kinase activity Ephrin-A4 H003069_01 AJ006352 42331 EFNA4 1.67 0.1254
213 0019199 transmembrane receptor protein kinase activity EphB4 H003096_01 U07695 155227 EPHB4 0.849 0.29767
214 0019199 transmembrane receptor protein kinase activity RYK receptor-like tyrosine kinase H003160_01 S59184 79350 RYK 0.838 0.49926
215 0019199 transmembrane receptor protein kinase activity V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene H003542_01 M11730 323910 ERBB2 1.004 0.98391
216 0019199 transmembrane receptor protein kinase activity Neurotrophic tyrosine kinase, receptor, type 3 H003588_01 U05012 26776 NTRK3 1.151 0.20942
217 0019199 transmembrane receptor protein kinase activity Platelet-derived growth factor receptor, beta polypeptide H003752_01 J03278 76144 PDGFRB 1.509 0.21888
218 0019199 transmembrane receptor protein kinase activity PTK7 protein tyrosine kinase 7 H003804_01 U33635 90572 PTK7 1.351 0.22758
219 0019199 transmembrane receptor protein kinase activity V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog H003808_01 X06182 81665 KIT 0.788 0.49109
220 0019199 transmembrane receptor protein kinase activity Activin A receptor, type IB H003853_01 Z22536 99954 ACVR1B 1.179 0.26984
221 0019199 transmembrane receptor protein kinase activity C-mer proto-oncogene tyrosine kinase H000425_01 U08023 306178 MERTK 0.944 0.86201
222 0019199 transmembrane receptor protein kinase activity Homo sapiens cDNA FLJ11309 fis, clone PLACE1010076 H006813_01 AK002171 28005 1.2 0.52528
223 0019199 transmembrane receptor protein kinase activity Latent transforming growth factor beta binding protein 1 H000940_01 M34057 241257 LTBP1 0.82 0.49965
224 0019199 transmembrane receptor protein kinase activity Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial CDS H013267_01 U88358 306251 1.182 0.39888
225 0019199 transmembrane receptor protein kinase activity Platelet-derived growth factor receptor-like H001341_01 D37965 170040 PDGFRL 0.652 0.09963
226 0000082 G1/S transition of mitotic cell cycle Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 82932 CCND1 1.251 0.36936
227 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 179665 CDKN1A 0.838 0.33129
228 0000082 G1/S transition of mitotic cell cycle Cell division cycle 34 H002232_01 L22005 76932 CDC34 1.415 0.21701
229 0000082 G1/S transition of mitotic cell cycle Cyclin E1 H002323_01 M74093 9700 CCNE1 1.288 0.47974
230 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) H002606_01 L20320 184298 CDK7 1.055 0.83498
231 0000082 G1/S transition of mitotic cell cycle Menage a trois 1 (CAK assembly factor) H000312_01 X87843 82380 MNAT1 0.689 0.32732
232 0000082 G1/S transition of mitotic cell cycle Cyclin A2 H002740_01 X51688 85137 CCNA2 1.344 0.24008
233 0000082 G1/S transition of mitotic cell cycle Cyclin G1 H002889_01 X77794 79101 CCNG1 0.613 0.00464
234 0000082 G1/S transition of mitotic cell cycle Cell division cycle 25C H003048_01 M34065 656 CDC25C 0.762 0.17709
235 0000082 G1/S transition of mitotic cell cycle CDC6 (cell division cycle 6, S. cerevisiae) homolog H003192_01 U77949 69563 CDC6 1.021 0.86789
236 0000082 G1/S transition of mitotic cell cycle General transcription factor IIH, polypeptide 1 (62kD subunit) H003500_01 M95809 89578 GTF2H1 1.304 0.40518
237 0000082 G1/S transition of mitotic cell cycle Cullin 2 H000387_01 U83410 82919 CUL2 1.456 0.24367
238 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 1C (p57, Kip2) H003594_01 U22398 106070 CDKN1C 1.211 0.40117
239 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) H003750_01 AF004819 72901 CDKN2B 1.264 0.44457
240 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 29656 CDKN2D 0.909 0.73706
241 0000082 G1/S transition of mitotic cell cycle Chromosome condensation 1 H000401_01 X12654 84746 CHC1 0.789 0.22395
242 0000082 G1/S transition of mitotic cell cycle CDC28 protein kinase 2 H000463_01 X54942 83758 CKS2 0.849 0.4051
243 0000082 G1/S transition of mitotic cell cycle RNA, U17D small nucleolar H005580_01 AJ006835 196769 RNU17D 1.352 0.3504
244 0000082 G1/S transition of mitotic cell cycle Cullin 4A H006657_01 U58090 183874 CUL4A 0.602 0.37343
245 0000082 G1/S transition of mitotic cell cycle Cyclin-E binding protein 1 H007016_01 AB027289 26663 LOC51191 1.057 0.91297
246 0000082 G1/S transition of mitotic cell cycle G1 to S phase transition 1 H000607_01 X17644 2707 GSPT1 1.06 0.69634
247 0000082 G1/S transition of mitotic cell cycle Cullin 5 H008068_01 X81882 101299 CUL5 0.892 0.48091
248 0000082 G1/S transition of mitotic cell cycle Cullin 1 H008496_01 AF062536 14541 CUL1 0.824 0.17857
249 0000082 G1/S transition of mitotic cell cycle Protein phosphatase 6, catalytic subunit H008575_01 X92972 279563 PPP6C 0.688 0.19804
250 0000082 G1/S transition of mitotic cell cycle Branched chain aminotransferase 1, cytosolic H008589_01 U21551 157205 BCAT1 1.516 0.15679
251 0000082 G1/S transition of mitotic cell cycle GAP-associated tyrosine phosphoprotein p62 (Sam68) H009232_01 M88108 119537 SAM68 0.663 0.15228
252 0000082 G1/S transition of mitotic cell cycle Cdk inhibitor p21 binding protein H010584_01 AB040450 279862 TOK-1 0.875 0.63115
253 0000082 G1/S transition of mitotic cell cycle Cyclin T2 H001491_01 AF048731 155478 CCNT2 0.884 0.75297
254 0000082 G1/S transition of mitotic cell cycle Cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) H001670_01 L25876 84113 CDKN3 0.581 0.10101
255 0030934 anchoring collagen Collagen, type VI, alpha 3 H001981_01 X52022 80988 COL6A3 1.236 0.26989
256 0030934 anchoring collagen Collagen, type XVI, alpha 1 H002090_01 M92642 26208 COL16A1 1.157 0.19594
257 0030934 anchoring collagen Collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) H002655_01 L02870 1640 COL7A1 1.292 0.26637
258 0030934 anchoring collagen Collagen, type VI, alpha 1 H000774_01 X15880 108885 COL6A1 1.311 0.20447
259 0030934 anchoring collagen Homo sapiens, alpha-1 (VI) collagen H001198_01 M20776 25459 1.299 0.34272