Comparative Gene Ontology Analysis of Scleroderma and Normal Fibroblasts:

Number of investigated GO categories: 1297
Random variance model was used

GO categories which discriminate among classes:
Table – Sorted by p-value of the LS permutation test.
The first 35 GO categories are significant at the nominal 0.01 level of the LS permutation test or KS permutation test

GO category GO description Number of genes LS Permutation p-value KS Permutation p-value
1 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		8 1e-05 0.00018
2 0006958 complement activation\, classical pathway 13 0.00113 0.08394
3 0006672 ceramide metabolism 7 0.00166 0.00067
4 0004030 aldehyde dehydrogenase [NAD(P)+] activity 5 0.00245 0.00549
5 0006692 prostanoid metabolism 5 0.00252 0.01296
6 0006693 prostaglandin metabolism 5 0.00252 0.01296
7 0004867 serine-type endopeptidase inhibitor activity 23 0.00345 0.0486
8 0016477 cell migration 26 0.00361 0.00642
9 0030934 anchoring collagen 6 0.00387 0.51802
10 0005201 extracellular matrix structural constituent 40 0.00405 0.09777
11 0006956 complement activation 16 0.00475 0.2066
12 0046519 sphingoid metabolism 9 0.00481 0.01755
13 0000323 lytic vacuole 54 0.00486 0.02689
14 0005764 lysosome 54 0.00486 0.02689
15 0005773 vacuole 54 0.00486 0.02689
16 0006690 icosanoid metabolism 11 0.0055 0.02742
17 0006000 fructose metabolism 8 0.00623 0.20487
18 0009986 cell surface 7 0.00643 0.35003
19 0007411 axon guidance 9 0.00695 0.24773
20 0006665 sphingolipid metabolism 17 0.00769 0.00484
21 0004028 aldehyde dehydrogenase activity 9 0.0084 0.06054
22 0005581 collagen 20 0.00911 0.49494
23 0045664 regulation of neuron differentiation 5 0.00918 0.34871
24 0051094 positive regulation of development 5 0.00959 0.33501
25 0045597 positive regulation of cell differentiation 5 0.00959 0.33501
26 0008154 actin polymerization and/or depolymerization 8 0.01866 0.00857
27 0008645 hexose transport 7 0.02172 0.00039
28 0015749 monosaccharide transport 7 0.02172 0.00039
29 0015758 glucose transport 7 0.02172 0.00039
30 0001871 pattern binding 40 0.02237 0.00552
31 0005087 Ran guanyl nucleotide exchange factor activity 5 0.02321 0.00157
32 0030246 carbohydrate binding 71 0.04249 0.00809
33 0030166 proteoglycan biosynthesis 5 0.09002 0.0035
34 0008047 enzyme activator activity 81 0.11346 0.00602
35 0015078 hydrogen ion transporter activity 73 0.29583 0.00747

Table Significant GO categories consist of the following genes:

GO category GO description Qiagen oligo ID Description GB acc UG cluster Gene symbol Geometric mean of ratios (Disease / Normal) p-value
1 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H001509_01 Aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II)		 D17793 78183 AKR1C3 0.465 3e-05
2 0016628 oxidoreductase activity\, acting on the CH-CH group of donors\, NAD or NADP as acceptor H002522_01 Dihydropyrimidine dehydrogenase U20938 1602 DPYD 0.866 0.08026
3 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H002933_01 Biliverdin reductase B (flavin reductase (NADPH)) D32143 76289 BLVRB 0.915 0.11985
4 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H003233_01 Biliverdin reductase A X93086 81029 BLVRA 0.909 0.06164
5 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H003858_01 Aldo-keto reductase family 1, member C2 (dihydrodiol
dehydrogenase 2; bile acid binding protein; 3-a		 U05598 201967 AKR1C2 0.517 4e-05
6 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H007766_01 Transmembrane 7 superfamily member 2 AF023676 31130 TM7SF2 0.85 0.04199
7 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H000726_01 7-dehydrocholesterol reductase AF034544 11806 DHCR7 0.94 0.38822
8 0016628 oxidoreductase activity\, acting on the CH-CH group of
donors\, NAD or NADP as acceptor 		H014963_01 Peroxisomal trans 2-enoyl CoA reductase; putative short chain
alcohol dehydrogenase		 AF119841 281680 HSA250303 1.096 0.09119
9 0006958 complement activation\, classical pathway H002203_01 Complement component 4-binding protein, alpha M31452 1012 C4BPA 0.981 0.7132
10 0006958 complement activation\, classical pathway H002407_01 I factor (complement) Y00318 36602 IF 0.87 0.08583
11 0006958 complement activation\, classical pathway H002469_01 Complement component 3 K02765 284394 C3 1.036 0.66839
12 0006958 complement activation\, classical pathway H002497_01 Complement component 1, r subcomponent M14058 1279 C1R 0.684 0.00136
13 0006958 complement activation\, classical pathway H002515_01 Clusterin (complement lysis inhibitor, SP-40,40, sulfated
glycoprotein 2, testosterone-repressed pro		 M25915 75106 CLU 0.91 0.46421
14 0006958 complement activation\, classical pathway H002605_01 Mannan-binding lectin serine protease 2 X98400 119983 MASP2 1.039 0.55015
15 0006958 complement activation\, classical pathway H002805_01 Membrane cofactor protein (CD46, trophoblast-lymphocyte
cross-reactive antigen)		 X59405 83532 MCP 0.784 0.0075
16 0006958 complement activation\, classical pathway H002996_01 Complement component (3d/Epstein Barr virus) receptor 2 J03565 73792 CR2 0.978 0.81221
17 0006958 complement activation\, classical pathway H003011_01 Complement component 1, s subcomponent J04080 169756 C1S 0.811 0.02135
18 0006958 complement activation\, classical pathway H003528_01 Decay accelerating factor for complement (CD55, Cromer blood
group system)		 M30142 1369 DAF 0.621 0
19 0006958 complement activation\, classical pathway H011506_01 Homo sapiens mRNA; cDNA DKFZp586F0824 (from clone
DKFZp586F0824); partial cds		 AL137646 146001 0.794 0.05535
20 0006958 complement activation\, classical pathway H001027_01 Complement component 8, alpha polypeptide M16974 93210 C8A 0.954 0.48929
21 0006958 complement activation\, classical pathway H001061_01 Complement component 4A K02403 170250 C4A 1.04 0.62746
22 0006672 ceramide metabolism H000025_01 Neutral sphingomyelinase (N-SMase) activation associated
factor		 X96586 78687 NSMAF 0.742 0.00058
23 0006672 ceramide metabolism H004193_01 Sialyltransferase 9 (CMP-NeuAc:lactosylceramide
alpha-2,3-sialyltransferase; GM3 synthase)		 AB018356 225939 SIAT9 0.814 0.06525
24 0006672 ceramide metabolism H000464_01 Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform		 M65254 108705 PPP2R1B 0.937 0.24318
25 0006672 ceramide metabolism H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
26 0006672 ceramide metabolism H000076_01 UDP-glucose ceramide glucosyltransferase D50840 152601 UGCG 0.81 0.01527
27 0006672 ceramide metabolism H001062_01 N-acylsphingosine amidohydrolase (acid ceramidase) U70063 75811 ASAH 0.761 0.00155
28 0006672 ceramide metabolism H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 0.883 0.0751
29 0004030 aldehyde dehydrogenase [NAD(P)+] activity H001547_01 Aldehyde dehydrogenase 3 family, member A1 M74542 575 ALDH3A1 1.208 0.02494
30 0004030 aldehyde dehydrogenase [NAD(P)+] activity H001572_01 Aldehyde dehydrogenase 3 family, member B2 U37519 87539 ALDH3B2 1.047 0.51127
31 0004030 aldehyde dehydrogenase [NAD(P)+] activity H002609_01 Aldehyde dehydrogenase 3 family, member B1 U10868 83155 ALDH3B1 0.893 0.05664
32 0004030 aldehyde dehydrogenase [NAD(P)+] activity H003022_01 Aldehyde dehydrogenase 1 family, member A3 U07919 75746 ALDH1A3 0.641 0.01304
33 0004030 aldehyde dehydrogenase [NAD(P)+] activity H003776_01 Aldehyde dehydrogenase 2 family (mitochondrial) X05409 195432 ALDH2 1.249 7e-05
34 0006692 prostanoid metabolism H001509_01 Aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II)		 D17793 78183 AKR1C3 0.465 3e-05
35 0006692 prostanoid metabolism H001562_01 Hydroxyprostaglandin dehydrogenase 15-(NAD) L76465 77348 HPGD 1.042 0.50286
36 0006692 prostanoid metabolism H001846_01 Unactive progesterone receptor, 23 kD L24804 278270 P23 0.825 0.05398
37 0006692 prostanoid metabolism H003299_01 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxygenase)		 M59979 88474 PTGS1 1.394 0.00734
38 0006692 prostanoid metabolism H006848_01 Prostaglandin D2 synthase (21kD, brain) NM_000954 8272 PTGDS 0.872 0.10275
39 0006693 prostaglandin metabolism H001509_01 Aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II)		 D17793 78183 AKR1C3 0.465 3e-05
40 0006693 prostaglandin metabolism H001562_01 Hydroxyprostaglandin dehydrogenase 15-(NAD) L76465 77348 HPGD 1.042 0.50286
41 0006693 prostaglandin metabolism H001846_01 Unactive progesterone receptor, 23 kD L24804 278270 P23 0.825 0.05398
42 0006693 prostaglandin metabolism H003299_01 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxygenase)		 M59979 88474 PTGS1 1.394 0.00734
43 0006693 prostaglandin metabolism H006848_01 Prostaglandin D2 synthase (21kD, brain) NM_000954 8272 PTGDS 0.872 0.10275
44 0004867 serine-type endopeptidase inhibitor activity H001614_01 Prostatic binding protein X75252 80423 PBP 1.121 0.01436
45 0004867 serine-type endopeptidase inhibitor activity H001778_01 Gastrointestinal peptide AF048700 129778 PEC-60 0.842 0.00941
46 0004867 serine-type endopeptidase inhibitor activity H001786_01 Serine protease inhibitor, Kazal type, 2 (acrosin-trypsin
inhibitor)		 X57655 98243 SPINK2 0.956 0.58868
47 0004867 serine-type endopeptidase inhibitor activity H001803_01 Serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8		 L40377 41726 SERPINB8 1.026 0.63053
48 0004867 serine-type endopeptidase inhibitor activity H001902_01 Alpha-2-macroglobulin M11313 74561 A2M 1.028 0.77516
49 0004867 serine-type endopeptidase inhibitor activity H001937_01 Serine (or cysteine) proteinase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 1		 X01683 297681 SERPINA1 1.004 0.95043
50 0004867 serine-type endopeptidase inhibitor activity H001981_01 Collagen, type VI, alpha 3 X52022 80988 COL6A3 1.173 0.0519
51 0004867 serine-type endopeptidase inhibitor activity H002016_01 Amyloid beta (A4) precursor-like protein 2 S60099 279518 APLP2 0.856 0.01972
52 0004867 serine-type endopeptidase inhibitor activity H002067_01 Pre-alpha (globulin) inhibitor, H3 polypeptide X67055 76716 ITIH3 0.925 0.23704
53 0004867 serine-type endopeptidase inhibitor activity H002283_01 Secretory leukocyte protease inhibitor (antileukoproteinase) X04470 251754 SLPI 0.907 0.1344
54 0004867 serine-type endopeptidase inhibitor activity H002553_01 Serine (or cysteine) proteinase inhibitor, clade E (nexin,
plasminogen activator inhibitor type 1),		 M14083 82085 SERPINE1 1.045 0.39102
55 0004867 serine-type endopeptidase inhibitor activity H002655_01 Collagen, type VII, alpha 1 (epidermolysis bullosa,
dystrophic, dominant and recessive)		 L02870 1640 COL7A1 1.553 p < 1e-07
56 0004867 serine-type endopeptidase inhibitor activity H002674_01 Serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1		 M93056 183583 SERPINB1 0.914 0.23786
57 0004867 serine-type endopeptidase inhibitor activity H002866_01 Tissue factor pathway inhibitor 2 D29992 295944 TFPI2 0.976 0.87235
58 0004867 serine-type endopeptidase inhibitor activity H002927_01 Serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2		 Y00630 75716 SERPINB2 1.092 0.4661
59 0004867 serine-type endopeptidase inhibitor activity H003006_01 Serine (or cysteine) proteinase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 8		 K02215 3697 SERPINA8 0.872 0.07808
60 0004867 serine-type endopeptidase inhibitor activity H003294_01 Serine (or cysteine) proteinase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 6		 NM_001756 1305 SERPINA6 1.034 0.53555
61 0004867 serine-type endopeptidase inhibitor activity H003880_01 Inter-alpha (globulin) inhibitor, H2 polypeptide X07173 75285 ITIH2 0.905 0.20987
62 0004867 serine-type endopeptidase inhibitor activity H000459_01 Serine protease inhibitor, Kunitz type, 2 AF027205 31439 SPINT2 0.921 0.22427
63 0004867 serine-type endopeptidase inhibitor activity H011225_01 Serine (or cysteine) proteinase inhibitor, clade I
(neuroserpin), member 2		 AB006423 158308 SERPINI2 0.836 0.09596
64 0004867 serine-type endopeptidase inhibitor activity H012614_01 Reversion-inducing-cysteine-rich protein with kazal motifs D50406 29640 RECK 0.716 0.02912
65 0004867 serine-type endopeptidase inhibitor activity H001117_01 Serine (or cysteine) proteinase inhibitor, clade H (heat
shock protein 47), member 2		 D83174 9930 SERPINH2 0.945 0.55266
66 0004867 serine-type endopeptidase inhibitor activity H001133_01 Epididymis-specific, whey-acidic protein type, four-disulfide
core; putative ovarian carcinoma marker		 X63187 2719 HE4 0.971 0.51353
67 0016477 cell migration H002710_01 Interleukin 10 M57627 193717 IL10 1.067 0.18138
68 0016477 cell migration H002937_01 Fibronectin 1 X02761 287820 FN1 1.038 0.4994
69 0016477 cell migration H002944_01 Interleukin 8 M17017 624 IL8 1.499 0.02976
70 0016477 cell migration H003013_01 Vascular endothelial growth factor C U43142 79141 VEGFC 1.208 0.03351
71 0016477 cell migration H003139_01 Integrin, beta 2 (antigen CD18 (p95), lymphocyte
function-associated antigen 1; macrophage antigen 1		 M15395 83968 ITGB2 0.932 0.49748
72 0016477 cell migration H003298_01 Laminin, alpha 4 S78569 78672 LAMA4 0.777 0.00645
73 0016477 cell migration H003652_01 Apolipoprotein E M12529 169401 APOE 1.005 0.94163
74 0016477 cell migration H003847_01 Laminin, alpha 2 (merosin, congenital muscular dystrophy) Z26653 75279 LAMA2 0.924 0.33276
75 0016477 cell migration H000396_01 Fasciculation and elongation protein zeta 1 (zygin I) U60060 79226 FEZ1 0.935 0.23095
76 0016477 cell migration H004459_01 Spondin 2, extracellular matrix protein NM_012445 288126 SPON2 0.926 0.37302
77 0016477 cell migration H006255_01 Syndecan binding protein (syntenin) AF000652 8180 SDCBP 0.83 0.02079
78 0016477 cell migration H007856_01 Chemokine-like factor, alternatively spliced NM_016951 15159 LOC51192 1.07 0.20793
79 0016477 cell migration H000663_01 Plexin B1 AB007867 278311 PLXNB1 0.852 0.02089
80 0016477 cell migration H008817_01 Prostate derived STE20-like kinase PSK NM_016151 66141 PSK 1.045 0.47302
81 0016477 cell migration H009347_01 Neuronal cell adhesion molecule AB002341 7912 NRCAM 0.584 1e-05
82 0016477 cell migration H010897_01 DKFZP434H168 protein AL117580 241431 DKFZP434H168 0.862 0.01431
83 0016477 cell migration H010900_01 Homo sapiens mRNA for plexin-B1 plasma membrane receptor,
truncated splice variant (plexin-B1/SEP ge		 AJ011414 312939 0.953 0.49831
84 0016477 cell migration H011466_01 Thousand and one amino acid protein kinase AB020688 122823 TAO1 0.99 0.82505
85 0016477 cell migration H012243_01 Dedicator of cyto-kinesis 2 D86964 17211 DOCK2 1.086 0.11723
86 0016477 cell migration H000901_01 Sema domain, immunoglobulin domain (Ig), short basic domain,
secreted, (semaphorin) 3B		 U28369 82222 SEMA3B 0.921 0.24356
87 0016477 cell migration H013086_01 Oligophrenin 1 AJ001189 128824 OPHN1 1.059 0.43883
88 0016477 cell migration H015948_01 Homo sapiens cDNA: FLJ22401 fis, clone HRC08032, highly
similar to AB027466 Homo sapiens SPON2 mRNA		 AK024499 306919 0.785 0.01505
89 0016477 cell migration H016066_01 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 321592 1.086 0.4075
90 0016477 cell migration H016249_01 Homo sapiens, Similar to laminin, alpha 4, clone MGC:10389,
mRNA, complete cds		 BC004241 327703 1.047 0.43404
91 0016477 cell migration H001178_01 Pregnancy specific beta-1-glycoprotein 11 M20882 321450 PSG11 0.862 0.07474
92 0016477 cell migration H001239_01 Sema domain, immunoglobulin domain (Ig), transmembrane domain
(TM) and short cytoplasmic domain, (se		 AB021292 25887 SEMA4F 0.972 0.6257
93 0030934 anchoring collagen H001981_01 Collagen, type VI, alpha 3 X52022 80988 COL6A3 1.173 0.0519
94 0030934 anchoring collagen H002090_01 Collagen, type XVI, alpha 1 M92642 26208 COL16A1 0.927 0.27606
95 0030934 anchoring collagen H002655_01 Collagen, type VII, alpha 1 (epidermolysis bullosa,
dystrophic, dominant and recessive)		 L02870 1640 COL7A1 1.553 p < 1e-07
96 0030934 anchoring collagen H000717_01 Collagen, type IX, alpha 3 L41162 53563 COL9A3 1.05 0.45955
97 0030934 anchoring collagen H000734_01 Collagen, type XIV, alpha 1 (undulin) Y11710 36131 COL14A1 1.002 0.98122
98 0030934 anchoring collagen H000774_01 Collagen, type VI, alpha 1 X15880 108885 COL6A1 1.005 0.94306
99 0005201 extracellular matrix structural constituent H001909_01 Collagen, type IV, alpha 2 X05610 75617 COL4A2 1.108 0.39407
100 0005201 extracellular matrix structural constituent H001981_01 Collagen, type VI, alpha 3 X52022 80988 COL6A3 1.173 0.0519
101 0005201 extracellular matrix structural constituent H002090_01 Collagen, type XVI, alpha 1 M92642 26208 COL16A1 0.927 0.27606
102 0005201 extracellular matrix structural constituent H002143_01 Fibrillin 1 (Marfan syndrome) X63556 750 FBN1 0.849 0.01231
103 0005201 extracellular matrix structural constituent H002160_01 Collagen, type V, alpha 2 Y14690 82985 COL5A2 0.867 0.10761
104 0005201 extracellular matrix structural constituent H002196_01 Nidogen (enactin) M30269 62041 NID 0.915 0.21702
105 0005201 extracellular matrix structural constituent H002207_01 Fibrillin 2 (congenital contractural arachnodactyly) U03272 79432 FBN2 1.137 0.50187
106 0005201 extracellular matrix structural constituent H002306_01 Collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV,
autosomal dominant)		 X14420 119571 COL3A1 0.907 0.39389
107 0005201 extracellular matrix structural constituent H002647_01 Collagen, type XV, alpha 1 L25286 83164 COL15A1 1.005 0.91556
108 0005201 extracellular matrix structural constituent H002655_01 Collagen, type VII, alpha 1 (epidermolysis bullosa,
dystrophic, dominant and recessive)		 L02870 1640 COL7A1 1.553 p < 1e-07
109 0005201 extracellular matrix structural constituent H002759_01 Collagen, type IV, alpha 6 D21337 408 COL4A6 1.025 0.70581
110 0005201 extracellular matrix structural constituent H002866_01 Tissue factor pathway inhibitor 2 D29992 295944 TFPI2 0.976 0.87235
111 0005201 extracellular matrix structural constituent H002915_01 Collagen, type VIII, alpha 1 X57527 114599 COL8A1 1.092 0.38509
112 0005201 extracellular matrix structural constituent H002937_01 Fibronectin 1 X02761 287820 FN1 1.038 0.4994
113 0005201 extracellular matrix structural constituent H002994_01 Collagen, type XVIII, alpha 1 AF018081 78409 COL18A1 1.757 8e-05
114 0005201 extracellular matrix structural constituent H003072_01 Collagen, type I, alpha 2 J03464 179573 COL1A2 0.954 0.62985
115 0005201 extracellular matrix structural constituent H003298_01 Laminin, alpha 4 S78569 78672 LAMA4 0.777 0.00645
116 0005201 extracellular matrix structural constituent H003413_01 Lumican U21128 79914 LUM 0.854 0.1425
117 0005201 extracellular matrix structural constituent H003593_01 Collagen, type VI, alpha 2 AL096746 159263 COL6A2 0.991 0.87376
118 0005201 extracellular matrix structural constituent H004095_01 Collagen, type V, alpha 3 AF177941 235368 COL5A3 1.07 0.41285
119 0005201 extracellular matrix structural constituent H004275_01 Elastin microfibril interface located protein AL050138 63348 EMILIN 0.965 0.50466
120 0005201 extracellular matrix structural constituent H005324_01 Elastin microfibril interface located protein NM_007046 63348 EMILIN 0.907 0.20922
121 0005201 extracellular matrix structural constituent H005515_01 EGF-containing fibulin-like extracellular matrix protein 2 AJ132819 6059 EFEMP2 0.982 0.79014
122 0005201 extracellular matrix structural constituent H006623_01 Homo sapiens clone HB-2 mRNA sequence AF216077 48376 1.142 0.17143
123 0005201 extracellular matrix structural constituent H000717_01 Collagen, type IX, alpha 3 L41162 53563 COL9A3 1.05 0.45955
124 0005201 extracellular matrix structural constituent H000734_01 Collagen, type XIV, alpha 1 (undulin) Y11710 36131 COL14A1 1.002 0.98122
125 0005201 extracellular matrix structural constituent H000774_01 Collagen, type VI, alpha 1 X15880 108885 COL6A1 1.005 0.94306
126 0005201 extracellular matrix structural constituent H011443_01 EGF-containing fibulin-like extracellular matrix protein 2 AF109121 6059 EFEMP2 1.132 0.12457
127 0005201 extracellular matrix structural constituent H011464_01 Microfibrillar-associated protein 3 AL049404 28785 MFAP3 1.034 0.57907
128 0005201 extracellular matrix structural constituent H012686_01 Collagen, type XIII, alpha 1 NM_005203 211933 COL13A1 1.064 0.5062
129 0005201 extracellular matrix structural constituent H000992_01 Fibulin 2 X82494 198862 FBLN2 1.019 0.79659
130 0005201 extracellular matrix structural constituent H014507_01 P3ECSL NM_022164 173508 LIECG3 0.934 0.25276
131 0005201 extracellular matrix structural constituent H001006_01 Microfibrillar-associated protein 3 AK000358 28785 MFAP3 0.934 0.32753
132 0005201 extracellular matrix structural constituent H015060_01 Smooth muscle cell-expressed and macrophage conditioned
medium-induced protein smag-64		 NM_020351 283100 LOC57086 1.121 0.13171
133 0005201 extracellular matrix structural constituent H016066_01 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 321592 1.086 0.4075
134 0005201 extracellular matrix structural constituent H016249_01 Homo sapiens, Similar to laminin, alpha 4, clone MGC:10389,
mRNA, complete cds		 BC004241 327703 1.047 0.43404
135 0005201 extracellular matrix structural constituent H001143_01 Matrilin 1, cartilage matrix protein M55683 150366 MATN1 1.128 0.03901
136 0005201 extracellular matrix structural constituent H001149_01 Microfibrillar-associated protein 2 U19718 83551 MFAP2 0.842 0.0108
137 0005201 extracellular matrix structural constituent H001163_01 Cartilage linking protein 1 U43328 2799 CRTL1 0.649 0.0585
138 0005201 extracellular matrix structural constituent H001200_01 Microfibril-associated glycoprotein-2 NM_003480 300946 MAGP2 0.792 0.02533
139 0006956 complement activation H002203_01 Complement component 4-binding protein, alpha M31452 1012 C4BPA 0.981 0.7132
140 0006956 complement activation H002407_01 I factor (complement) Y00318 36602 IF 0.87 0.08583
141 0006956 complement activation H002469_01 Complement component 3 K02765 284394 C3 1.036 0.66839
142 0006956 complement activation H002497_01 Complement component 1, r subcomponent M14058 1279 C1R 0.684 0.00136
143 0006956 complement activation H002509_01 D component of complement (adipsin) M84526 155597 DF 1.01 0.8622
144 0006956 complement activation H002515_01 Clusterin (complement lysis inhibitor, SP-40,40, sulfated
glycoprotein 2, testosterone-repressed pro		 M25915 75106 CLU 0.91 0.46421
145 0006956 complement activation H002605_01 Mannan-binding lectin serine protease 2 X98400 119983 MASP2 1.039 0.55015
146 0006956 complement activation H002805_01 Membrane cofactor protein (CD46, trophoblast-lymphocyte
cross-reactive antigen)		 X59405 83532 MCP 0.784 0.0075
147 0006956 complement activation H002996_01 Complement component (3d/Epstein Barr virus) receptor 2 J03565 73792 CR2 0.978 0.81221
148 0006956 complement activation H003011_01 Complement component 1, s subcomponent J04080 169756 C1S 0.811 0.02135
149 0006956 complement activation H003337_01 B-factor, properdin L15702 69771 BF 0.972 0.75801
150 0006956 complement activation H003528_01 Decay accelerating factor for complement (CD55, Cromer blood
group system)		 M30142 1369 DAF 0.621 0
151 0006956 complement activation H011506_01 Homo sapiens mRNA; cDNA DKFZp586F0824 (from clone
DKFZp586F0824); partial cds		 AL137646 146001 0.794 0.05535
152 0006956 complement activation H001027_01 Complement component 8, alpha polypeptide M16974 93210 C8A 0.954 0.48929
153 0006956 complement activation H001061_01 Complement component 4A K02403 170250 C4A 1.04 0.62746
154 0006956 complement activation H015664_01 Human MHC class III serum complement factor B, mRNA K01566 294163 1.018 0.82251
155 0046519 sphingoid metabolism H000025_01 Neutral sphingomyelinase (N-SMase) activation associated
factor		 X96586 78687 NSMAF 0.742 0.00058
156 0046519 sphingoid metabolism H004193_01 Sialyltransferase 9 (CMP-NeuAc:lactosylceramide
alpha-2,3-sialyltransferase; GM3 synthase)		 AB018356 225939 SIAT9 0.814 0.06525
157 0046519 sphingoid metabolism H000464_01 Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform		 M65254 108705 PPP2R1B 0.937 0.24318
158 0046519 sphingoid metabolism H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
159 0046519 sphingoid metabolism H000076_01 UDP-glucose ceramide glucosyltransferase D50840 152601 UGCG 0.81 0.01527
160 0046519 sphingoid metabolism H001062_01 N-acylsphingosine amidohydrolase (acid ceramidase) U70063 75811 ASAH 0.761 0.00155
161 0046519 sphingoid metabolism H015734_01 Sphingosine kinase type 2 isoform AL136701 301305 SPHK2 1.009 0.87246
162 0046519 sphingoid metabolism H016485_01 Sphingosine kinase 1 NM_021972 68061 SPHK1 1.013 0.883
163 0046519 sphingoid metabolism H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 0.883 0.0751
164 0000323 lytic vacuole H001771_01 Cathepsin S M90696 181301 CTSS 1.092 0.12339
165 0000323 lytic vacuole H001912_01 Hyaluronoglucosaminidase 1 U03056 75619 HYAL1 0.963 0.64564
166 0000323 lytic vacuole H001982_01 Deoxyribonuclease II, lysosomal AF060222 118243 DNASE2 0.851 0.00663
167 0000323 lytic vacuole H002064_01 Galactosidase, beta 1 M34423 79222 GLB1 0.816 0.01277
168 0000323 lytic vacuole H002077_01 Glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) Z12173 321070 GNS 0.93 0.26928
169 0000323 lytic vacuole H002157_01 Prolylcarboxypeptidase (angiotensinase C) L13977 75693 PRCP 0.815 0.00463
170 0000323 lytic vacuole H002162_01 Lysosomal-associated membrane protein 2 U36336 8262 LAMP2 0.864 0.01474
171 0000323 lytic vacuole H002185_01 Niemann-Pick disease, type C1 AF002020 76918 NPC1 0.803 0.00028
172 0000323 lytic vacuole H002206_01 Protease, cysteine, 1 (legumain) D55696 18069 PRSC1 1.008 0.90457
173 0000323 lytic vacuole H002235_01 Ubiquitin specific protease 6 (Tre-2 oncogene) X63547 111065 USP6 0.954 0.41203
174 0000323 lytic vacuole H002290_01 Acid phosphatase 5, tartrate resistant NM_001611 1211 ACP5 1.087 0.31928
175 0000323 lytic vacuole H002483_01 Lysosomal-associated membrane protein 1 J04182 150101 LAMP1 0.925 0.0685
176 0000323 lytic vacuole H002697_01 Myeloperoxidase M19507 1817 MPO 1.015 0.85413
177 0000323 lytic vacuole H002897_01 Cathepsin L X12451 78056 CTSL 0.808 0.00407
178 0000323 lytic vacuole H002948_01 Ubiquitin specific protease 4 (proto-oncogene) U20657 77500 USP4 1.105 0.14385
179 0000323 lytic vacuole H003016_01 Insulin-like growth factor 2 receptor Y00285 76473 IGF2R 0.825 0.00995
180 0000323 lytic vacuole H003024_01 Cathepsin H X16832 288181 CTSH 0.804 0.02033
181 0000323 lytic vacuole H003138_01 Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl
hydrolase)		 U55206 78619 GGH 1.034 0.64814
182 0000323 lytic vacuole H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 0.957 0.41765
183 0000323 lytic vacuole H003254_01 Cathepsin C X87212 10029 CTSC 0.996 0.97068
184 0000323 lytic vacuole H003300_01 CD36 antigen (collagen type I receptor, thrombospondin
receptor)-like 2 (lysosomal integral membrane		 D12676 323567 CD36L2 1.055 0.33252
185 0000323 lytic vacuole H003466_01 CD68 antigen S57235 246381 CD68 0.988 0.7745
186 0000323 lytic vacuole H003574_01 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 D64015 182741 TIAL1 1.011 0.83837
187 0000323 lytic vacuole H003805_01 Lipase A, lysosomal acid, cholesterol esterase (Wolman
disease)		 X76488 85226 LIPA 0.896 0.24882
188 0000323 lytic vacuole H003836_01 Glucuronidase, beta M15182 183868 GUSB 0.974 0.68456
189 0000323 lytic vacuole H005593_01 Homo sapiens clone 23645 mRNA sequence AF052100 6651 0.956 0.57587
190 0000323 lytic vacuole H006334_01 LCAT-like lysophospholipase AL110209 6770 LLPL 0.897 0.14363
191 0000323 lytic vacuole H006538_01 Ceroid-lipofuscinosis, neuronal 5 AF068227 30213 CLN5 0.933 0.28364
192 0000323 lytic vacuole H007373_01 Prenylcysteine lyase AB020715 278627 PCL1 1.03 0.62083
193 0000323 lytic vacuole H007535_01 Hyaluronoglucosaminidase 2 U09577 76873 HYAL2 0.961 0.37587
194 0000323 lytic vacuole H000633_01 Coronin, actin-binding protein, 1A D44497 109606 CORO1A 0.945 0.24739
195 0000323 lytic vacuole H008567_01 Sialidase 1 (lysosomal sialidase) AF040958 118721 NEU1 0.833 0.01207
196 0000323 lytic vacuole H009939_01 Hypothetical protein AF151020 181444 LOC51235 1.017 0.74195
197 0000323 lytic vacuole H000751_01 Anti-oxidant protein 2 (non-selenium glutathione peroxidase,
acidic calcium-independent phospholipas		 D14662 120 KIAA0106 1.121 0.08672
198 0000323 lytic vacuole H010783_01 Palmitoyl-protein thioesterase 2 AF020544 81737 PPT2 0.999 0.99101
199 0000323 lytic vacuole H000868_01 Mannosidase, beta A, lysosomal U60337 115945 MANBA 0.922 0.19365
200 0000323 lytic vacuole H000877_01 Sphingomyelin phosphodiesterase 1, acid lysosomal (acid
sphingomyelinase)		 X59960 77813 SMPD1 0.93 0.19544
201 0000323 lytic vacuole H000879_01 Chitobiase, di-N-acetyl- M95767 135578 CTBS 0.907 0.15643
202 0000323 lytic vacuole H012397_01 ESTs X78261 272177 1.028 0.65963
203 0000323 lytic vacuole H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic
leukodystrophy)		 J03077 78575 PSAP 0.85 0.03087
204 0000323 lytic vacuole H012727_01 Cathepsin F NM_003793 11590 CTSF 0.993 0.93097
205 0000323 lytic vacuole H000926_01 Transmembrane 4 superfamily member 3 M35252 84072 TM4SF3 1.04 0.49676
206 0000323 lytic vacuole H000932_01 N-sulfoglucosamine sulfohydrolase (sulfamidase) U30894 31074 SGSH 0.929 0.35523
207 0000323 lytic vacuole H014980_01 Glucosidase, beta; acid (includes glucosylceramidase) NM_000157 282997 GBA 0.882 0.09493
208 0000323 lytic vacuole H001062_01 N-acylsphingosine amidohydrolase (acid ceramidase) U70063 75811 ASAH 0.761 0.00155
209 0000323 lytic vacuole H001066_01 Fucosidase, alpha-L- 1, tissue M29877 576 FUCA1 0.914 0.19066
210 0000323 lytic vacuole H015633_01 GM2 ganglioside activator protein NM_000405 289082 GM2A 1.007 0.91285
211 0000323 lytic vacuole H015696_01 Cathepsin B NM_001908 297939 CTSB 0.918 0.30063
212 0000323 lytic vacuole H001083_01 Low density lipoprotein-related protein 2 U33837 153595 LRP2 0.925 0.20154
213 0000323 lytic vacuole H001085_01 Mannosidase, alpha, class 2B, member 1 U68382 279854 MAN2B1 1.039 0.56235
214 0000323 lytic vacuole H001116_01 Steroid sulfatase (microsomal), arylsulfatase C, isozyme S M16505 79876 STS 0.812 0.00508
215 0000323 lytic vacuole H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 0.883 0.0751
216 0000323 lytic vacuole H001177_01 Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis,
neuronal 1, infantile)		 U44772 3873 PPT1 0.987 0.84861
217 0000323 lytic vacuole H001185_01 Arylsulfatase A NM_000487 88251 ARSA 0.904 0.14918
218 0005764 lysosome H001771_01 Cathepsin S M90696 181301 CTSS 1.092 0.12339
219 0005764 lysosome H001912_01 Hyaluronoglucosaminidase 1 U03056 75619 HYAL1 0.963 0.64564
220 0005764 lysosome H001982_01 Deoxyribonuclease II, lysosomal AF060222 118243 DNASE2 0.851 0.00663
221 0005764 lysosome H002064_01 Galactosidase, beta 1 M34423 79222 GLB1 0.816 0.01277
222 0005764 lysosome H002077_01 Glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) Z12173 321070 GNS 0.93 0.26928
223 0005764 lysosome H002157_01 Prolylcarboxypeptidase (angiotensinase C) L13977 75693 PRCP 0.815 0.00463
224 0005764 lysosome H002162_01 Lysosomal-associated membrane protein 2 U36336 8262 LAMP2 0.864 0.01474
225 0005764 lysosome H002185_01 Niemann-Pick disease, type C1 AF002020 76918 NPC1 0.803 0.00028
226 0005764 lysosome H002206_01 Protease, cysteine, 1 (legumain) D55696 18069 PRSC1 1.008 0.90457
227 0005764 lysosome H002235_01 Ubiquitin specific protease 6 (Tre-2 oncogene) X63547 111065 USP6 0.954 0.41203
228 0005764 lysosome H002290_01 Acid phosphatase 5, tartrate resistant NM_001611 1211 ACP5 1.087 0.31928
229 0005764 lysosome H002483_01 Lysosomal-associated membrane protein 1 J04182 150101 LAMP1 0.925 0.0685
230 0005764 lysosome H002697_01 Myeloperoxidase M19507 1817 MPO 1.015 0.85413
231 0005764 lysosome H002897_01 Cathepsin L X12451 78056 CTSL 0.808 0.00407
232 0005764 lysosome H002948_01 Ubiquitin specific protease 4 (proto-oncogene) U20657 77500 USP4 1.105 0.14385
233 0005764 lysosome H003016_01 Insulin-like growth factor 2 receptor Y00285 76473 IGF2R 0.825 0.00995
234 0005764 lysosome H003024_01 Cathepsin H X16832 288181 CTSH 0.804 0.02033
235 0005764 lysosome H003138_01 Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl
hydrolase)		 U55206 78619 GGH 1.034 0.64814
236 0005764 lysosome H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 0.957 0.41765
237 0005764 lysosome H003254_01 Cathepsin C X87212 10029 CTSC 0.996 0.97068
238 0005764 lysosome H003300_01 CD36 antigen (collagen type I receptor, thrombospondin
receptor)-like 2 (lysosomal integral membrane		 D12676 323567 CD36L2 1.055 0.33252
239 0005764 lysosome H003466_01 CD68 antigen S57235 246381 CD68 0.988 0.7745
240 0005764 lysosome H003574_01 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 D64015 182741 TIAL1 1.011 0.83837
241 0005764 lysosome H003805_01 Lipase A, lysosomal acid, cholesterol esterase (Wolman
disease)		 X76488 85226 LIPA 0.896 0.24882
242 0005764 lysosome H003836_01 Glucuronidase, beta M15182 183868 GUSB 0.974 0.68456
243 0005764 lysosome H005593_01 Homo sapiens clone 23645 mRNA sequence AF052100 6651 0.956 0.57587
244 0005764 lysosome H006334_01 LCAT-like lysophospholipase AL110209 6770 LLPL 0.897 0.14363
245 0005764 lysosome H006538_01 Ceroid-lipofuscinosis, neuronal 5 AF068227 30213 CLN5 0.933 0.28364
246 0005764 lysosome H007373_01 Prenylcysteine lyase AB020715 278627 PCL1 1.03 0.62083
247 0005764 lysosome H007535_01 Hyaluronoglucosaminidase 2 U09577 76873 HYAL2 0.961 0.37587
248 0005764 lysosome H000633_01 Coronin, actin-binding protein, 1A D44497 109606 CORO1A 0.945 0.24739
249 0005764 lysosome H008567_01 Sialidase 1 (lysosomal sialidase) AF040958 118721 NEU1 0.833 0.01207
250 0005764 lysosome H009939_01 Hypothetical protein AF151020 181444 LOC51235 1.017 0.74195
251 0005764 lysosome H000751_01 Anti-oxidant protein 2 (non-selenium glutathione peroxidase,
acidic calcium-independent phospholipas		 D14662 120 KIAA0106 1.121 0.08672
252 0005764 lysosome H010783_01 Palmitoyl-protein thioesterase 2 AF020544 81737 PPT2 0.999 0.99101
253 0005764 lysosome H000868_01 Mannosidase, beta A, lysosomal U60337 115945 MANBA 0.922 0.19365
254 0005764 lysosome H000877_01 Sphingomyelin phosphodiesterase 1, acid lysosomal (acid
sphingomyelinase)		 X59960 77813 SMPD1 0.93 0.19544
255 0005764 lysosome H000879_01 Chitobiase, di-N-acetyl- M95767 135578 CTBS 0.907 0.15643
256 0005764 lysosome H012397_01 ESTs X78261 272177 1.028 0.65963
257 0005764 lysosome H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic
leukodystrophy)		 J03077 78575 PSAP 0.85 0.03087
258 0005764 lysosome H012727_01 Cathepsin F NM_003793 11590 CTSF 0.993 0.93097
259 0005764 lysosome H000926_01 Transmembrane 4 superfamily member 3 M35252 84072 TM4SF3 1.04 0.49676
260 0005764 lysosome H000932_01 N-sulfoglucosamine sulfohydrolase (sulfamidase) U30894 31074 SGSH 0.929 0.35523
261 0005764 lysosome H014980_01 Glucosidase, beta; acid (includes glucosylceramidase) NM_000157 282997 GBA 0.882 0.09493
262 0005764 lysosome H001062_01 N-acylsphingosine amidohydrolase (acid ceramidase) U70063 75811 ASAH 0.761 0.00155
263 0005764 lysosome H001066_01 Fucosidase, alpha-L- 1, tissue M29877 576 FUCA1 0.914 0.19066
264 0005764 lysosome H015633_01 GM2 ganglioside activator protein NM_000405 289082 GM2A 1.007 0.91285
265 0005764 lysosome H015696_01 Cathepsin B NM_001908 297939 CTSB 0.918 0.30063
266 0005764 lysosome H001083_01 Low density lipoprotein-related protein 2 U33837 153595 LRP2 0.925 0.20154
267 0005764 lysosome H001085_01 Mannosidase, alpha, class 2B, member 1 U68382 279854 MAN2B1 1.039 0.56235
268 0005764 lysosome H001116_01 Steroid sulfatase (microsomal), arylsulfatase C, isozyme S M16505 79876 STS 0.812 0.00508
269 0005764 lysosome H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 0.883 0.0751
270 0005764 lysosome H001177_01 Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis,
neuronal 1, infantile)		 U44772 3873 PPT1 0.987 0.84861
271 0005764 lysosome H001185_01 Arylsulfatase A NM_000487 88251 ARSA 0.904 0.14918
272 0005773 vacuole H001771_01 Cathepsin S M90696 181301 CTSS 1.092 0.12339
273 0005773 vacuole H001912_01 Hyaluronoglucosaminidase 1 U03056 75619 HYAL1 0.963 0.64564
274 0005773 vacuole H001982_01 Deoxyribonuclease II, lysosomal AF060222 118243 DNASE2 0.851 0.00663
275 0005773 vacuole H002064_01 Galactosidase, beta 1 M34423 79222 GLB1 0.816 0.01277
276 0005773 vacuole H002077_01 Glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) Z12173 321070 GNS 0.93 0.26928
277 0005773 vacuole H002157_01 Prolylcarboxypeptidase (angiotensinase C) L13977 75693 PRCP 0.815 0.00463
278 0005773 vacuole H002162_01 Lysosomal-associated membrane protein 2 U36336 8262 LAMP2 0.864 0.01474
279 0005773 vacuole H002185_01 Niemann-Pick disease, type C1 AF002020 76918 NPC1 0.803 0.00028
280 0005773 vacuole H002206_01 Protease, cysteine, 1 (legumain) D55696 18069 PRSC1 1.008 0.90457
281 0005773 vacuole H002235_01 Ubiquitin specific protease 6 (Tre-2 oncogene) X63547 111065 USP6 0.954 0.41203
282 0005773 vacuole H002290_01 Acid phosphatase 5, tartrate resistant NM_001611 1211 ACP5 1.087 0.31928
283 0005773 vacuole H002483_01 Lysosomal-associated membrane protein 1 J04182 150101 LAMP1 0.925 0.0685
284 0005773 vacuole H002697_01 Myeloperoxidase M19507 1817 MPO 1.015 0.85413
285 0005773 vacuole H002897_01 Cathepsin L X12451 78056 CTSL 0.808 0.00407
286 0005773 vacuole H002948_01 Ubiquitin specific protease 4 (proto-oncogene) U20657 77500 USP4 1.105 0.14385
287 0005773 vacuole H003016_01 Insulin-like growth factor 2 receptor Y00285 76473 IGF2R 0.825 0.00995
288 0005773 vacuole H003024_01 Cathepsin H X16832 288181 CTSH 0.804 0.02033
289 0005773 vacuole H003138_01 Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl
hydrolase)		 U55206 78619 GGH 1.034 0.64814
290 0005773 vacuole H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 0.957 0.41765
291 0005773 vacuole H003254_01 Cathepsin C X87212 10029 CTSC 0.996 0.97068
292 0005773 vacuole H003300_01 CD36 antigen (collagen type I receptor, thrombospondin
receptor)-like 2 (lysosomal integral membrane		 D12676 323567 CD36L2 1.055 0.33252
293 0005773 vacuole H003466_01 CD68 antigen S57235 246381 CD68 0.988 0.7745
294 0005773 vacuole H003574_01 TIA1 cytotoxic granule-associated RNA-binding protein-like 1 D64015 182741 TIAL1 1.011 0.83837
295 0005773 vacuole H003805_01 Lipase A, lysosomal acid, cholesterol esterase (Wolman
disease)		 X76488 85226 LIPA 0.896 0.24882
296 0005773 vacuole H003836_01 Glucuronidase, beta M15182 183868 GUSB 0.974 0.68456
297 0005773 vacuole H005593_01 Homo sapiens clone 23645 mRNA sequence AF052100 6651 0.956 0.57587
298 0005773 vacuole H006334_01 LCAT-like lysophospholipase AL110209 6770 LLPL 0.897 0.14363
299 0005773 vacuole H006538_01 Ceroid-lipofuscinosis, neuronal 5 AF068227 30213 CLN5 0.933 0.28364
300 0005773 vacuole H007373_01 Prenylcysteine lyase AB020715 278627 PCL1 1.03 0.62083
301 0005773 vacuole H007535_01 Hyaluronoglucosaminidase 2 U09577 76873 HYAL2 0.961 0.37587
302 0005773 vacuole H000633_01 Coronin, actin-binding protein, 1A D44497 109606 CORO1A 0.945 0.24739
303 0005773 vacuole H008567_01 Sialidase 1 (lysosomal sialidase) AF040958 118721 NEU1 0.833 0.01207
304 0005773 vacuole H009939_01 Hypothetical protein AF151020 181444 LOC51235 1.017 0.74195
305 0005773 vacuole H000751_01 Anti-oxidant protein 2 (non-selenium glutathione peroxidase,
acidic calcium-independent phospholipas		 D14662 120 KIAA0106 1.121 0.08672
306 0005773 vacuole H010783_01 Palmitoyl-protein thioesterase 2 AF020544 81737 PPT2 0.999 0.99101
307 0005773 vacuole H000868_01 Mannosidase, beta A, lysosomal U60337 115945 MANBA 0.922 0.19365
308 0005773 vacuole H000877_01 Sphingomyelin phosphodiesterase 1, acid lysosomal (acid
sphingomyelinase)		 X59960 77813 SMPD1 0.93 0.19544
309 0005773 vacuole H000879_01 Chitobiase, di-N-acetyl- M95767 135578 CTBS 0.907 0.15643
310 0005773 vacuole H012397_01 ESTs X78261 272177 1.028 0.65963
311 0005773 vacuole H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic
leukodystrophy)		 J03077 78575 PSAP 0.85 0.03087
312 0005773 vacuole H012727_01 Cathepsin F NM_003793 11590 CTSF 0.993 0.93097
313 0005773 vacuole H000926_01 Transmembrane 4 superfamily member 3 M35252 84072 TM4SF3 1.04 0.49676
314 0005773 vacuole H000932_01 N-sulfoglucosamine sulfohydrolase (sulfamidase) U30894 31074 SGSH 0.929 0.35523
315 0005773 vacuole H014980_01 Glucosidase, beta; acid (includes glucosylceramidase) NM_000157 282997 GBA 0.882 0.09493
316 0005773 vacuole H001062_01 N-acylsphingosine amidohydrolase (acid ceramidase) U70063 75811 ASAH 0.761 0.00155
317 0005773 vacuole H001066_01 Fucosidase, alpha-L- 1, tissue M29877 576 FUCA1 0.914 0.19066
318 0005773 vacuole H015633_01 GM2 ganglioside activator protein NM_000405 289082 GM2A 1.007 0.91285
319 0005773 vacuole H015696_01 Cathepsin B NM_001908 297939 CTSB 0.918 0.30063
320 0005773 vacuole H001083_01 Low density lipoprotein-related protein 2 U33837 153595 LRP2 0.925 0.20154
321 0005773 vacuole H001085_01 Mannosidase, alpha, class 2B, member 1 U68382 279854 MAN2B1 1.039 0.56235
322 0005773 vacuole H001116_01 Steroid sulfatase (microsomal), arylsulfatase C, isozyme S M16505 79876 STS 0.812 0.00508
323 0005773 vacuole H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 0.883 0.0751
324 0005773 vacuole H001177_01 Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis,
neuronal 1, infantile)		 U44772 3873 PPT1 0.987 0.84861
325 0005773 vacuole H001185_01 Arylsulfatase A NM_000487 88251 ARSA 0.904 0.14918
326 0006690 icosanoid metabolism H001509_01 Aldo-keto reductase family 1, member C3 (3-alpha
hydroxysteroid dehydrogenase, type II)		 D17793 78183 AKR1C3 0.465 3e-05
327 0006690 icosanoid metabolism H001543_01 Cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase)
polypeptide 2		 U37143 152096 CYP2J2 1.006 0.93641
328 0006690 icosanoid metabolism H001562_01 Hydroxyprostaglandin dehydrogenase 15-(NAD) L76465 77348 HPGD 1.042 0.50286
329 0006690 icosanoid metabolism H001773_01 Leukotriene A4 hydrolase J03459 81118 LTA4H 1.061 0.16921
330 0006690 icosanoid metabolism H001846_01 Unactive progesterone receptor, 23 kD L24804 278270 P23 0.825 0.05398
331 0006690 icosanoid metabolism H003299_01 Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H
synthase and cyclooxygenase)		 M59979 88474 PTGS1 1.394 0.00734
332 0006690 icosanoid metabolism H003774_01 Phospholipase A2, group IVA (cytosolic, calcium-dependent) M72393 211587 PLA2G4A 0.854 0.04496
333 0006690 icosanoid metabolism H000390_01 Microsomal glutathione S-transferase 2 U77604 81874 MGST2 1.203 0.02993
334 0006690 icosanoid metabolism H006848_01 Prostaglandin D2 synthase (21kD, brain) NM_000954 8272 PTGDS 0.872 0.10275
335 0006690 icosanoid metabolism H011138_01 Arachidonate 12-lipoxygenase, 12R type AF038461 136574 ALOX12B 0.981 0.77087
336 0006690 icosanoid metabolism H001135_01 Gamma-glutamyltransferase-like activity 1 AL117414 1675 GGTLA1 1.032 0.53679
337 0006000 fructose metabolism H001385_01 Phosphofructokinase, liver X15573 155455 PFKL 1.053 0.23567
338 0006000 fructose metabolism H003374_01 Aldolase A, fructose-bisphosphate M11560 273415 ALDOA 1.008 0.86656
339 0006000 fructose metabolism H004823_01 Aldolase C, fructose-bisphosphate AF054987 155247 ALDOC 0.954 0.4786
340 0006000 fructose metabolism H005445_01 Homo sapiens clone 25028 mRNA sequence AF131846 13396 0.874 0.03765
341 0006000 fructose metabolism H005940_01 Glutamine-fructose-6-phosphate transaminase 1 M90516 1674 GFPT1 1.108 0.25479
342 0006000 fructose metabolism H007211_01 Glutamine-fructose-6-phosphate transaminase 2 AB016789 30332 GFPT2 0.825 0.09538
343 0006000 fructose metabolism H007688_01 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 AF109735 195471 PFKFB3 1.453 0
344 0006000 fructose metabolism H011651_01 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 X52638 739 PFKFB1 1.023 0.6794
345 0009986 cell surface H001650_01 Chloride channel 3 X78520 174139 CLCN3 0.973 0.66948
346 0009986 cell surface H002338_01 Fibroblast growth factor 10 U67918 248049 FGF10 1.018 0.84482
347 0009986 cell surface H005818_01 KIAA1077 protein AB029000 70823 KIAA1077 0.94 0.74856
348 0009986 cell surface H006086_01 Notch (Drosophila) homolog 2 AL133036 8121 NOTCH2 0.988 0.86836
349 0009986 cell surface H009347_01 Neuronal cell adhesion molecule AB002341 7912 NRCAM 0.584 1e-05
350 0009986 cell surface H010125_01 Similar to glucosamine-6-sulfatases AB033073 43857 KIAA1247 0.865 0.09813
351 0009986 cell surface H016122_01 TMTSP for transmembrane molecule with thrombospondin module NM_018676 325667 LOC55901 1.313 0.00083
352 0007411 axon guidance H003652_01 Apolipoprotein E M12529 169401 APOE 1.005 0.94163
353 0007411 axon guidance H000396_01 Fasciculation and elongation protein zeta 1 (zygin I) U60060 79226 FEZ1 0.935 0.23095
354 0007411 axon guidance H004459_01 Spondin 2, extracellular matrix protein NM_012445 288126 SPON2 0.926 0.37302
355 0007411 axon guidance H009347_01 Neuronal cell adhesion molecule AB002341 7912 NRCAM 0.584 1e-05
356 0007411 axon guidance H010897_01 DKFZP434H168 protein AL117580 241431 DKFZP434H168 0.862 0.01431
357 0007411 axon guidance H000901_01 Sema domain, immunoglobulin domain (Ig), short basic domain,
secreted, (semaphorin) 3B		 U28369 82222 SEMA3B 0.921 0.24356
358 0007411 axon guidance H013086_01 Oligophrenin 1 AJ001189 128824 OPHN1 1.059 0.43883
359 0007411 axon guidance H015948_01 Homo sapiens cDNA: FLJ22401 fis, clone HRC08032, highly
similar to AB027466 Homo sapiens SPON2 mRNA		 AK024499 306919 0.785 0.01505
360 0007411 axon guidance H001239_01 Sema domain, immunoglobulin domain (Ig), transmembrane domain
(TM) and short cytoplasmic domain, (se		 AB021292 25887 SEMA4F 0.972 0.6257
361 0006665 sphingolipid metabolism H001450_01 Globotriaosylceramide/CD77 synthase; Gb3/CD77 synthase;
alpha1,4-galactosyltransferase; 4-N-acetylgl		 NM_017436 105956 A14GALT 0.933 0.31929
362 0006665 sphingolipid metabolism H000025_01 Neutral sphingomyelinase (N-SMase) activation associated
factor		 X96586 78687 NSMAF 0.742 0.00058
363 0006665 sphingolipid metabolism H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 0.957 0.41765
364 0006665 sphingolipid metabolism H004193_01 Sialyltransferase 9 (CMP-NeuAc:lactosylceramide
alpha-2,3-sialyltransferase; GM3 synthase)		 AB018356 225939 SIAT9 0.814 0.06525
365 0006665 sphingolipid metabolism H000464_01 Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform		 M65254 108705 PPP2R1B 0.937 0.24318
366 0006665 sphingolipid metabolism H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
367 0006665 sphingolipid metabolism H000076_01 UDP-glucose ceramide glucosyltransferase D50840 152601 UGCG 0.81 0.01527
368 0006665 sphingolipid metabolism H000877_01 Sphingomyelin phosphodiesterase 1, acid lysosomal (acid
sphingomyelinase)		 X59960 77813 SMPD1 0.93 0.19544
369 0006665 sphingolipid metabolism H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic
leukodystrophy)		 J03077 78575 PSAP 0.85 0.03087
370 0006665 sphingolipid metabolism H001022_01 UDP glycosyltransferase 8 (UDP-galactose ceramide
galactosyltransferase)		 U30930 158540 UGT8 0.898 0.18479
371 0006665 sphingolipid metabolism H014980_01 Glucosidase, beta; acid (includes glucosylceramidase) NM_000157 282997 GBA 0.882 0.09493
372 0006665 sphingolipid metabolism H001062_01 N-acylsphingosine amidohydrolase (acid ceramidase) U70063 75811 ASAH 0.761 0.00155
373 0006665 sphingolipid metabolism H015633_01 GM2 ganglioside activator protein NM_000405 289082 GM2A 1.007 0.91285
374 0006665 sphingolipid metabolism H015734_01 Sphingosine kinase type 2 isoform AL136701 301305 SPHK2 1.009 0.87246
375 0006665 sphingolipid metabolism H016485_01 Sphingosine kinase 1 NM_021972 68061 SPHK1 1.013 0.883
376 0006665 sphingolipid metabolism H001148_01 Galactosylceramidase (Krabbe disease) NM_000153 273 GALC 0.883 0.0751
377 0006665 sphingolipid metabolism H001185_01 Arylsulfatase A NM_000487 88251 ARSA 0.904 0.14918
378 0004028 aldehyde dehydrogenase activity H001508_01 Aldehyde dehydrogenase 4 family, member A1 U24266 77448 ALDH4A1 1.071 0.21045
379 0004028 aldehyde dehydrogenase activity H001525_01 Aldehyde dehydrogenase 7 family, member A1 S74728 74294 ALDH7A1 1.065 0.29052
380 0004028 aldehyde dehydrogenase activity H001547_01 Aldehyde dehydrogenase 3 family, member A1 M74542 575 ALDH3A1 1.208 0.02494
381 0004028 aldehyde dehydrogenase activity H001572_01 Aldehyde dehydrogenase 3 family, member B2 U37519 87539 ALDH3B2 1.047 0.51127
382 0004028 aldehyde dehydrogenase activity H002609_01 Aldehyde dehydrogenase 3 family, member B1 U10868 83155 ALDH3B1 0.893 0.05664
383 0004028 aldehyde dehydrogenase activity H002656_01 Aldehyde dehydrogenase 9 family, member A1 U34252 2533 ALDH9A1 0.971 0.54467
384 0004028 aldehyde dehydrogenase activity H003022_01 Aldehyde dehydrogenase 1 family, member A3 U07919 75746 ALDH1A3 0.641 0.01304
385 0004028 aldehyde dehydrogenase activity H003659_01 Aldehyde dehydrogenase 3 family, member A2 U46689 159608 ALDH3A2 0.939 0.45817
386 0004028 aldehyde dehydrogenase activity H003776_01 Aldehyde dehydrogenase 2 family (mitochondrial) X05409 195432 ALDH2 1.249 7e-05
387 0005581 collagen H001909_01 Collagen, type IV, alpha 2 X05610 75617 COL4A2 1.108 0.39407
388 0005581 collagen H001981_01 Collagen, type VI, alpha 3 X52022 80988 COL6A3 1.173 0.0519
389 0005581 collagen H002090_01 Collagen, type XVI, alpha 1 M92642 26208 COL16A1 0.927 0.27606
390 0005581 collagen H002160_01 Collagen, type V, alpha 2 Y14690 82985 COL5A2 0.867 0.10761
391 0005581 collagen H002306_01 Collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV,
autosomal dominant)		 X14420 119571 COL3A1 0.907 0.39389
392 0005581 collagen H002647_01 Collagen, type XV, alpha 1 L25286 83164 COL15A1 1.005 0.91556
393 0005581 collagen H002655_01 Collagen, type VII, alpha 1 (epidermolysis bullosa,
dystrophic, dominant and recessive)		 L02870 1640 COL7A1 1.553 p < 1e-07
394 0005581 collagen H002759_01 Collagen, type IV, alpha 6 D21337 408 COL4A6 1.025 0.70581
395 0005581 collagen H002915_01 Collagen, type VIII, alpha 1 X57527 114599 COL8A1 1.092 0.38509
396 0005581 collagen H002994_01 Collagen, type XVIII, alpha 1 AF018081 78409 COL18A1 1.757 8e-05
397 0005581 collagen H003072_01 Collagen, type I, alpha 2 J03464 179573 COL1A2 0.954 0.62985
398 0005581 collagen H003413_01 Lumican U21128 79914 LUM 0.854 0.1425
399 0005581 collagen H003593_01 Collagen, type VI, alpha 2 AL096746 159263 COL6A2 0.991 0.87376
400 0005581 collagen H004095_01 Collagen, type V, alpha 3 AF177941 235368 COL5A3 1.07 0.41285
401 0005581 collagen H006623_01 Homo sapiens clone HB-2 mRNA sequence AF216077 48376 1.142 0.17143
402 0005581 collagen H000717_01 Collagen, type IX, alpha 3 L41162 53563 COL9A3 1.05 0.45955
403 0005581 collagen H000734_01 Collagen, type XIV, alpha 1 (undulin) Y11710 36131 COL14A1 1.002 0.98122
404 0005581 collagen H000774_01 Collagen, type VI, alpha 1 X15880 108885 COL6A1 1.005 0.94306
405 0005581 collagen H012686_01 Collagen, type XIII, alpha 1 NM_005203 211933 COL13A1 1.064 0.5062
406 0005581 collagen H015060_01 Smooth muscle cell-expressed and macrophage conditioned
medium-induced protein smag-64		 NM_020351 283100 LOC57086 1.121 0.13171
407 0045664 regulation of neuron differentiation H000594_01 STAT induced STAT inhibitor-2 NM_003877 110776 STATI2 1.151 0.02953
408 0045664 regulation of neuron differentiation H009347_01 Neuronal cell adhesion molecule AB002341 7912 NRCAM 0.584 1e-05
409 0045664 regulation of neuron differentiation H010570_01 CGI-05 protein NM_016408 306044 LOC51654 0.988 0.8359
410 0045664 regulation of neuron differentiation H011007_01 Hypothetical protein FLJ10867 AL133161 32360 FLJ10867 1.077 0.33347
411 0045664 regulation of neuron differentiation H012950_01 Neuroligin 1 AB028993 71132 NLGN1 1.04 0.60029
412 0051094 positive regulation of development H002747_01 CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) U04343 27954 CD86 1.044 0.58602
413 0051094 positive regulation of development H002920_01 Nitric oxide synthase 2A (inducible, hepatocytes) X73029 193788 NOS2A 0.964 0.62365
414 0051094 positive regulation of development H000594_01 STAT induced STAT inhibitor-2 NM_003877 110776 STATI2 1.151 0.02953
415 0051094 positive regulation of development H009347_01 Neuronal cell adhesion molecule AB002341 7912 NRCAM 0.584 1e-05
416 0051094 positive regulation of development H012804_01 KIAA0670 protein/acinus NM_014977 227133 KIAA0670 1.029 0.53851
417 0045597 positive regulation of cell differentiation H002747_01 CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) U04343 27954 CD86 1.044 0.58602
418 0045597 positive regulation of cell differentiation H002920_01 Nitric oxide synthase 2A (inducible, hepatocytes) X73029 193788 NOS2A 0.964 0.62365
419 0045597 positive regulation of cell differentiation H000594_01 STAT induced STAT inhibitor-2 NM_003877 110776 STATI2 1.151 0.02953
420 0045597 positive regulation of cell differentiation H009347_01 Neuronal cell adhesion molecule AB002341 7912 NRCAM 0.584 1e-05
421 0045597 positive regulation of cell differentiation H012804_01 KIAA0670 protein/acinus NM_014977 227133 KIAA0670 1.029 0.53851
422 0008154 actin polymerization and/or depolymerization H002337_01 Stromal cell-derived factor 1 L36033 237356 SDF1 1.223 0.07778
423 0008154 actin polymerization and/or depolymerization H000031_01 Gelsolin (amyloidosis, Finnish type) X04412 290070 GSN 1.01 0.86337
424 0008154 actin polymerization and/or depolymerization H003673_01 NCK adaptor protein 1 X17576 54589 NCK1 0.815 0.01282
425 0008154 actin polymerization and/or depolymerization H004619_01 Profilin 2 AL096719 91747 PFN2 1.165 0.07894
426 0008154 actin polymerization and/or depolymerization H005560_01 WAS protein family, member 1 D87459 75850 WASF1 0.744 0.00067
427 0008154 actin polymerization and/or depolymerization H006859_01 Actin-related protein 3-beta AF023453 12887 ARP3BETA 0.984 0.81334
428 0008154 actin polymerization and/or depolymerization H010725_01 Capping protein (actin filament), gelsolin-like M94345 82422 CAPG 0.888 0.15506
429 0008154 actin polymerization and/or depolymerization H014805_01 Wiskott-Aldrich syndrome protein interacting protein NM_003387 24143 WASPIP 1.114 0.09014
430 0008645 hexose transport H001728_01 Phosphoprotein enriched in astrocytes 15 X86809 194673 PEA15 0.88 0.07395
431 0008645 hexose transport H002308_01 Solute carrier family 2 (facilitated glucose transporter),
member 3		 M20681 7594 SLC2A3 0.837 0.00747
432 0008645 hexose transport H004625_01 Homolog of mouse MAT-1 oncogene L37385 278268 HUMMAT1H 0.905 0.11366
433 0008645 hexose transport H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
434 0008645 hexose transport H010794_01 Solute carrier family 2, (facilitated glucose transporter)
member 8		 AJ245937 10574 SLC2A8 1.065 0.21771
435 0008645 hexose transport H015891_01 Solute carrier family 2 (facilitated glucose transporter),
member 10		 AF321240 305971 SLC2A10 0.837 0.01643
436 0008645 hexose transport H016613_01 Solute carrier family 2 (facilitated glucose transporter),
member 9		 NM_020041 95497 SLC2A9 1.099 0.122
437 0015749 monosaccharide transport H001728_01 Phosphoprotein enriched in astrocytes 15 X86809 194673 PEA15 0.88 0.07395
438 0015749 monosaccharide transport H002308_01 Solute carrier family 2 (facilitated glucose transporter),
member 3		 M20681 7594 SLC2A3 0.837 0.00747
439 0015749 monosaccharide transport H004625_01 Homolog of mouse MAT-1 oncogene L37385 278268 HUMMAT1H 0.905 0.11366
440 0015749 monosaccharide transport H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
441 0015749 monosaccharide transport H010794_01 Solute carrier family 2, (facilitated glucose transporter)
member 8		 AJ245937 10574 SLC2A8 1.065 0.21771
442 0015749 monosaccharide transport H015891_01 Solute carrier family 2 (facilitated glucose transporter),
member 10		 AF321240 305971 SLC2A10 0.837 0.01643
443 0015749 monosaccharide transport H016613_01 Solute carrier family 2 (facilitated glucose transporter),
member 9		 NM_020041 95497 SLC2A9 1.099 0.122
444 0015758 glucose transport H001728_01 Phosphoprotein enriched in astrocytes 15 X86809 194673 PEA15 0.88 0.07395
445 0015758 glucose transport H002308_01 Solute carrier family 2 (facilitated glucose transporter),
member 3		 M20681 7594 SLC2A3 0.837 0.00747
446 0015758 glucose transport H004625_01 Homolog of mouse MAT-1 oncogene L37385 278268 HUMMAT1H 0.905 0.11366
447 0015758 glucose transport H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
448 0015758 glucose transport H010794_01 Solute carrier family 2, (facilitated glucose transporter)
member 8		 AJ245937 10574 SLC2A8 1.065 0.21771
449 0015758 glucose transport H015891_01 Solute carrier family 2 (facilitated glucose transporter),
member 10		 AF321240 305971 SLC2A10 0.837 0.01643
450 0015758 glucose transport H016613_01 Solute carrier family 2 (facilitated glucose transporter),
member 9		 NM_020041 95497 SLC2A9 1.099 0.122
451 0001871 pattern binding H001945_01 CD14 antigen X13334 75627 CD14 0.884 0.1688
452 0001871 pattern binding H002047_01 Transforming growth factor, beta receptor III (betaglycan,
300kD)		 L07594 79059 TGFBR3 0.759 0.04091
453 0001871 pattern binding H002052_01 Thrombospondin 2 L12350 108623 THBS2 0.88 0.14324
454 0001871 pattern binding H002068_01 Thrombospondin 1 X14787 87409 THBS1 0.8 0.06406
455 0001871 pattern binding H002081_01 Placental growth factor, vascular endothelial growth
factor-related protein		 X54936 2894 PGF 0.967 0.66427
456 0001871 pattern binding H002117_01 Apolipoprotein B (including Ag(x) antigen) X04506 585 APOB 1.016 0.83969
457 0001871 pattern binding H002255_01 Diphtheria toxin receptor (heparin-binding epidermal growth
factor-like growth factor)		 M60278 799 DTR 1.17 0.04855
458 0001871 pattern binding H002338_01 Fibroblast growth factor 10 U67918 248049 FGF10 1.018 0.84482
459 0001871 pattern binding H002416_01 Apolipoprotein H (beta-2-glycoprotein I) M62839 1252 APOH 0.92 0.41415
460 0001871 pattern binding H002423_01 Vascular endothelial growth factor B U43368 78781 VEGFB 0.756 5e-04
461 0001871 pattern binding H002455_01 Aggrecan 1 (chondroitin sulfate proteoglycan 1, large
aggregating proteoglycan, antigen identified b		 NM_013227 2159 AGC1 1.144 0.21683
462 0001871 pattern binding H002481_01 fibroblast growth factor 2 (basic) J04513 56066 FGF2 0.926 0.38612
463 0001871 pattern binding H002643_01 Low density lipoprotein-related protein-associated protein 1
(alpha-2-macroglobulin receptor-associa		 M63959 75140 LRPAP1 0.944 0.16274
464 0001871 pattern binding H002764_01 Lipase, hepatic X07228 9994 LIPC 0.916 0.25156
465 0001871 pattern binding H002800_01 Connective tissue growth factor X78947 75511 CTGF 0.876 0.33394
466 0001871 pattern binding H002937_01 Fibronectin 1 X02761 287820 FN1 1.038 0.4994
467 0001871 pattern binding H000319_01 Zinc finger protein 146 X70394 301819 ZNF146 1.007 0.91633
468 0001871 pattern binding H002997_01 Vascular endothelial growth factor AF022375 73793 VEGF 0.988 0.80629
469 0001871 pattern binding H003065_01 Osteoblast specific factor 2 (fasciclin I-like) D13666 136348 OSF-2 0.735 0.1187
470 0001871 pattern binding H003296_01 Hepatoma-derived growth factor (high-mobility group protein
1-like)		 D16431 89525 HDGF 0.919 0.14242
471 0001871 pattern binding H003524_01 Vitronectin (serum spreading factor, somatomedin B,
complement S-protein)		 X03168 2257 VTN 1.057 0.39236
472 0001871 pattern binding H003599_01 Fibroblast growth factor 9 (glia-activating factor) D14838 111 FGF9 0.899 0.09819
473 0001871 pattern binding H003652_01 Apolipoprotein E M12529 169401 APOE 1.005 0.94163
474 0001871 pattern binding H006492_01 Homo sapiens CD44 isoform RC (CD44) mRNA, complete cds AF098641 306278 1.375 0.00024
475 0001871 pattern binding H006775_01 A disintegrin-like and metalloprotease (reprolysin type) with
thrombospondin type 1 motif, 1		 AB037767 8230 ADAMTS1 0.83 0.08206
476 0001871 pattern binding H000589_01 Cysteine-rich, angiogenic inducer, 61 Y11307 8867 CYR61 0.972 0.71628
477 0001871 pattern binding H008128_01 Midkine (neurite growth-promoting factor 2) X55110 82045 MDK 0.882 0.11138
478 0001871 pattern binding H008330_01 Lipase, endothelial NM_006033 65370 LIPG 0.958 0.66293
479 0001871 pattern binding H009385_01 Hypothetical protein DKFZp434E0321 AL133021 8658 FELL 0.934 0.31156
480 0001871 pattern binding H000723_01 Angio-associated, migratory cell protein M95627 83347 AAMP 1.016 0.69353
481 0001871 pattern binding H010264_01 Human transformation-related protein mRNA, 3' end L24521 300705 1.079 0.10122
482 0001871 pattern binding H000841_01 Amyloid beta (A4) precursor-like protein 1 U48437 74565 APLP1 0.998 0.97187
483 0001871 pattern binding H000953_01 Amiloride binding protein 1 (amine oxidase
(copper-containing))		 U11863 75741 ABP1 0.91 0.08931
484 0001871 pattern binding H013962_01 Latent transforming growth factor beta binding protein 4 Y13622 85087 LTBP4 1.075 0.29926
485 0001871 pattern binding H001073_01 Thrombospondin 3 L38969 169875 THBS3 0.797 0.01708
486 0001871 pattern binding H015675_01 Follistatin-like 1 BC000055 296267 FSTL1 0.888 0.06529
487 0001871 pattern binding H016066_01 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 321592 1.086 0.4075
488 0001871 pattern binding H016437_01 Hypothetical protein SBBI67 NM_020393 58356 LOC57115 0.931 0.16891
489 0001871 pattern binding H001163_01 Cartilage linking protein 1 U43328 2799 CRTL1 0.649 0.0585
490 0001871 pattern binding H001337_01 Homo sapiens mRNA; cDNA DKFZp586E0524 (from clone
DKFZp586E0524)		 AL110153 326249 0.891 0.03193
491 0005087 Ran guanyl nucleotide exchange factor activity H000401_01 Chromosome condensation 1 X12654 84746 CHC1 1.109 0.06564
492 0005087 Ran guanyl nucleotide exchange factor activity H004699_01 Chromosome condensation 1-like AF060219 27007 CHC1L 0.911 0.18699
493 0005087 Ran guanyl nucleotide exchange factor activity H005580_01 RNA, U17D small nucleolar AJ006835 196769 RNU17D 1.19 0.01592
494 0005087 Ran guanyl nucleotide exchange factor activity H014346_01 Homo sapiens cDNA FLJ12962 fis, clone NT2RP2005694, weakly
similar to X-LINKED RETINITIS PIGMENTOSA		 AK023024 149391 1.172 0.01171
495 0005087 Ran guanyl nucleotide exchange factor activity H014937_01 KIAA1563 protein AB046783 27669 KIAA1563 0.879 0.13441
496 0030246 carbohydrate binding H002042_01 Polycystic kidney disease 1 (autosomal dominant) L33243 75813 PKD1 0.945 0.20851
497 0030246 carbohydrate binding H002047_01 Transforming growth factor, beta receptor III (betaglycan,
300kD)		 L07594 79059 TGFBR3 0.759 0.04091
498 0030246 carbohydrate binding H002052_01 Thrombospondin 2 L12350 108623 THBS2 0.88 0.14324
499 0030246 carbohydrate binding H002053_01 CD72 antigen M54992 116481 CD72 0.982 0.74516
500 0030246 carbohydrate binding H002068_01 Thrombospondin 1 X14787 87409 THBS1 0.8 0.06406
501 0030246 carbohydrate binding H002081_01 Placental growth factor, vascular endothelial growth
factor-related protein		 X54936 2894 PGF 0.967 0.66427
502 0030246 carbohydrate binding H002117_01 Apolipoprotein B (including Ag(x) antigen) X04506 585 APOB 1.016 0.83969
503 0030246 carbohydrate binding H002255_01 Diphtheria toxin receptor (heparin-binding epidermal growth
factor-like growth factor)		 M60278 799 DTR 1.17 0.04855
504 0030246 carbohydrate binding H002338_01 Fibroblast growth factor 10 U67918 248049 FGF10 1.018 0.84482
505 0030246 carbohydrate binding H002395_01 Calnexin L10284 155560 CANX 1.015 0.74622
506 0030246 carbohydrate binding H002416_01 Apolipoprotein H (beta-2-glycoprotein I) M62839 1252 APOH 0.92 0.41415
507 0030246 carbohydrate binding H002423_01 Vascular endothelial growth factor B U43368 78781 VEGFB 0.756 5e-04
508 0030246 carbohydrate binding H002455_01 Aggrecan 1 (chondroitin sulfate proteoglycan 1, large
aggregating proteoglycan, antigen identified b		 NM_013227 2159 AGC1 1.144 0.21683
509 0030246 carbohydrate binding H002481_01 fibroblast growth factor 2 (basic) J04513 56066 FGF2 0.926 0.38612
510 0030246 carbohydrate binding H002643_01 Low density lipoprotein-related protein-associated protein 1
(alpha-2-macroglobulin receptor-associa		 M63959 75140 LRPAP1 0.944 0.16274
511 0030246 carbohydrate binding H002764_01 Lipase, hepatic X07228 9994 LIPC 0.916 0.25156
512 0030246 carbohydrate binding H002800_01 Connective tissue growth factor X78947 75511 CTGF 0.876 0.33394
513 0030246 carbohydrate binding H002931_01 Selectin L (lymphocyte adhesion molecule 1) M25280 82848 SELL 0.942 0.32569
514 0030246 carbohydrate binding H002937_01 Fibronectin 1 X02761 287820 FN1 1.038 0.4994
515 0030246 carbohydrate binding H000319_01 Zinc finger protein 146 X70394 301819 ZNF146 1.007 0.91633
516 0030246 carbohydrate binding H002997_01 Vascular endothelial growth factor AF022375 73793 VEGF 0.988 0.80629
517 0030246 carbohydrate binding H003065_01 Osteoblast specific factor 2 (fasciclin I-like) D13666 136348 OSF-2 0.735 0.1187
518 0030246 carbohydrate binding H003289_01 Killer cell lectin-like receptor subfamily D, member 1 NM_002262 41682 KLRD1 1.042 0.50408
519 0030246 carbohydrate binding H003296_01 Hepatoma-derived growth factor (high-mobility group protein
1-like)		 D16431 89525 HDGF 0.919 0.14242
520 0030246 carbohydrate binding H003524_01 Vitronectin (serum spreading factor, somatomedin B,
complement S-protein)		 X03168 2257 VTN 1.057 0.39236
521 0030246 carbohydrate binding H003599_01 Fibroblast growth factor 9 (glia-activating factor) D14838 111 FGF9 0.899 0.09819
522 0030246 carbohydrate binding H003652_01 Apolipoprotein E M12529 169401 APOE 1.005 0.94163
523 0030246 carbohydrate binding H003890_01 Myelin associated glycoprotein M29273 1780 MAG 1.197 0.00625
524 0030246 carbohydrate binding H004739_01 DiGeorge syndrome gene D L77561 83775 DGS-D 0.983 0.82507
525 0030246 carbohydrate binding H005212_01 C-type (calcium dependent, carbohydrate-recognition domain)
lectin, superfamily member 2 (activation		 X96719 85201 CLECSF2 1.001 0.99201
526 0030246 carbohydrate binding H005445_01 Homo sapiens clone 25028 mRNA sequence AF131846 13396 0.874 0.03765
527 0030246 carbohydrate binding H005586_01 Endoplasmic reticulum glycoprotein U10362 75864 GP36B 0.988 0.82613
528 0030246 carbohydrate binding H005940_01 Glutamine-fructose-6-phosphate transaminase 1 M90516 1674 GFPT1 1.108 0.25479
529 0030246 carbohydrate binding H006119_01 C-type (calcium dependent, carbohydrate-recognition domain)
lectin, superfamily member 5		 AJ271684 126355 CLECSF5 1.033 0.56841
530 0030246 carbohydrate binding H000541_01 Stem cell growth factor; lymphocyte secreted C-type lectin AF020044 105927 SCGF 1.085 0.15994
531 0030246 carbohydrate binding H006492_01 Homo sapiens CD44 isoform RC (CD44) mRNA, complete cds AF098641 306278 1.375 0.00024
532 0030246 carbohydrate binding H006775_01 A disintegrin-like and metalloprotease (reprolysin type) with
thrombospondin type 1 motif, 1		 AB037767 8230 ADAMTS1 0.83 0.08206
533 0030246 carbohydrate binding H007165_01 Collectin sub-family member 10 (C-type lectin) AB002631 176615 COLEC10 0.992 0.90126
534 0030246 carbohydrate binding H007211_01 Glutamine-fructose-6-phosphate transaminase 2 AB016789 30332 GFPT2 0.825 0.09538
535 0030246 carbohydrate binding H000589_01 Cysteine-rich, angiogenic inducer, 61 Y11307 8867 CYR61 0.972 0.71628
536 0030246 carbohydrate binding H008128_01 Midkine (neurite growth-promoting factor 2) X55110 82045 MDK 0.882 0.11138
537 0030246 carbohydrate binding H008262_01 Lectomedin-2 AB020628 107054 KIAA0821 1.007 0.87272
538 0030246 carbohydrate binding H008301_01 Sialic acid binding Ig-like lectin 7 AJ007395 274470 SIGLEC7 1.027 0.61102
539 0030246 carbohydrate binding H008330_01 Lipase, endothelial NM_006033 65370 LIPG 0.958 0.66293
540 0030246 carbohydrate binding H000672_01 KIAA0022 gene product D14664 2441 KIAA0022 1.157 0.06571
541 0030246 carbohydrate binding H008650_01 Endocytic receptor (macrophage mannose receptor family) AB014609 7835 KIAA0709 1.04 0.47157
542 0030246 carbohydrate binding H008709_01 D-siglec precursor, AF178981 149250 LOC51766 1.19 0.00898
543 0030246 carbohydrate binding H009007_01 Attractin AF106861 194019 ATRN 1.113 0.09964
544 0030246 carbohydrate binding H009385_01 Hypothetical protein DKFZp434E0321 AL133021 8658 FELL 0.934 0.31156
545 0030246 carbohydrate binding H000715_01 Phospholipase A2 receptor 1, 180kD U17033 171945 PLA2R1 1.128 0.15487
546 0030246 carbohydrate binding H000723_01 Angio-associated, migratory cell protein M95627 83347 AAMP 1.016 0.69353
547 0030246 carbohydrate binding H009608_01 Absent in melanoma 1 U83115 161002 AIM1 1.366 0.03118
548 0030246 carbohydrate binding H009943_01 Sialic acid binding Ig-like lectin 8 NM_014442 279751 SIGLEC8 1.01 0.86899
549 0030246 carbohydrate binding H010264_01 Human transformation-related protein mRNA, 3' end L24521 300705 1.079 0.10122
550 0030246 carbohydrate binding H010933_01 Lectin, galactoside-binding, soluble, 3 (galectin 3) AB006780 621 LGALS3 1.013 0.87132
551 0030246 carbohydrate binding H000813_01 Tetranectin (plasminogen-binding protein) X64559 65424 TNA 0.817 0.03798
552 0030246 carbohydrate binding H000841_01 Amyloid beta (A4) precursor-like protein 1 U48437 74565 APLP1 0.998 0.97187
553 0030246 carbohydrate binding H011506_01 Homo sapiens mRNA; cDNA DKFZp586F0824 (from clone
DKFZp586F0824); partial cds		 AL137646 146001 0.794 0.05535
554 0030246 carbohydrate binding H011742_01 Killer cell lectin-like receptor F1 AF175206 183125 KLRF1 0.973 0.60636
555 0030246 carbohydrate binding H000953_01 Amiloride binding protein 1 (amine oxidase
(copper-containing))		 U11863 75741 ABP1 0.91 0.08931
556 0030246 carbohydrate binding H013962_01 Latent transforming growth factor beta binding protein 4 Y13622 85087 LTBP4 1.075 0.29926
557 0030246 carbohydrate binding H000975_01 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
N-acetylgalactosaminyltransferase 1 (GalNAc-T1)		 U41514 80120 GALNT1 1.037 0.55496
558 0030246 carbohydrate binding H014626_01 Tumor endothelial marker 1 precursor NM_020404 195727 TEM1 0.992 0.89021
559 0030246 carbohydrate binding H001073_01 Thrombospondin 3 L38969 169875 THBS3 0.797 0.01708
560 0030246 carbohydrate binding H015675_01 Follistatin-like 1 BC000055 296267 FSTL1 0.888 0.06529
561 0030246 carbohydrate binding H001093_01 Asialoglycoprotein receptor 2 X55284 1259 ASGR2 0.881 0.06
562 0030246 carbohydrate binding H016066_01 Homo sapiens mRNA for MSF-FN70 (FN gene) AJ276395 321592 1.086 0.4075
563 0030246 carbohydrate binding H001163_01 Cartilage linking protein 1 U43328 2799 CRTL1 0.649 0.0585
564 0030246 carbohydrate binding H001238_01 Asialoglycoprotein receptor 1 M10058 12056 ASGR1 0.974 0.63722
565 0030246 carbohydrate binding H001257_01 DiGeorge syndrome critical region gene 2 D79985 2491 DGCR2 0.966 0.49242
566 0030246 carbohydrate binding H001337_01 Homo sapiens mRNA; cDNA DKFZp586E0524 (from clone
DKFZp586E0524)		 AL110153 326249 0.891 0.03193
567 0030166 proteoglycan biosynthesis H004560_01 Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 NM_006041 159572 HS3ST3B1 1.102 0.12948
568 0030166 proteoglycan biosynthesis H011024_01 KIAA0836 protein AB020643 183006 KIAA0836 0.901 0.11901
569 0030166 proteoglycan biosynthesis H000873_01 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 U18932 20894 NDST1 0.848 0.0317
570 0030166 proteoglycan biosynthesis H014535_01 Hypothetical protein PRO0082 NM_018590 180758 PRO0082 0.903 0.22169
571 0030166 proteoglycan biosynthesis H014852_01 Chondroitin 4-O-sulfotransferase 2 NM_018641 25204 C4S-2 1.082 0.08933
572 0008047 enzyme activator activity H001587_01 GDP dissociation inhibitor 1 X79353 74576 GDI1 1.078 0.10423
573 0008047 enzyme activator activity H001600_01 RAS p21 protein activator (GTPase activating protein) 1 M23379 758 RASA1 1.159 0.03328
574 0008047 enzyme activator activity H001612_01 RAP1, GTP-GDP dissociation stimulator 1 AF237413 7940 RAP1GDS1 0.845 0.00358
575 0008047 enzyme activator activity H001635_01 GDP dissociation inhibitor 2 Y13286 56845 GDI2 1.065 0.19057
576 0008047 enzyme activator activity H001668_01 Secretory granule, neuroendocrine protein 1 (7B2 protein) Y00757 2265 SGNE1 1.036 0.74881
577 0008047 enzyme activator activity H001717_01 RAP1, GTPase activating protein 1 M64788 75151 RAP1GA1 0.904 0.22222
578 0008047 enzyme activator activity H001752_01 Ran GTPase activating protein 1 X82260 183800 RANGAP1 1.12 0.29546
579 0008047 enzyme activator activity H001881_01 Proteasome (prosome, macropain) activator subunit 2 (PA28
beta)		 D45248 179774 PSME2 1.109 0.08468
580 0008047 enzyme activator activity H001975_01 Rho GDP dissociation inhibitor (GDI) beta L20688 83656 ARHGDIB 1.056 0.5118
581 0008047 enzyme activator activity H000256_01 IQ motif containing GTPase activating protein 2 U51903 78993 IQGAP2 0.995 0.93649
582 0008047 enzyme activator activity H002535_01 Rho GDP dissociation inhibitor (GDI) alpha X69550 159161 ARHGDIA 1.048 0.31969
583 0008047 enzyme activator activity H002630_01 Rho GTPase activating protein 1 U02570 138860 ARHGAP1 0.899 0.14521
584 0008047 enzyme activator activity H000294_01 Deleted in liver cancer 1 AF035119 8700 DLC1 0.955 0.53925
585 0008047 enzyme activator activity H003045_01 Tumor necrosis factor receptor superfamily, member 10b AF016266 51233 TNFRSF10B 0.97 0.5882
586 0008047 enzyme activator activity H003235_01 GM2 ganglioside activator protein X62078 69743 GM2A 0.957 0.41765
587 0008047 enzyme activator activity H003264_01 Caspase 9, apoptosis-related cysteine protease U60521 100641 CASP9 0.979 0.7713
588 0008047 enzyme activator activity H003339_01 Heat shock 27kD protein 2 D89617 78846 HSPB2 0.933 0.25345
589 0008047 enzyme activator activity H003366_01 Rho GTPase activating protein 4 X78817 3109 ARHGAP4 0.956 0.53411
590 0008047 enzyme activator activity H003392_01 Matrix metalloproteinase 15 (membrane-inserted) Z48482 80343 MMP15 0.953 0.57585
591 0008047 enzyme activator activity H003441_01 Breakpoint cluster region X02596 234799 BCR 0.978 0.70681
592 0008047 enzyme activator activity H003632_01 Neurofibromin 1 (neurofibromatosis, von Recklinghausen
disease, Watson disease)		 M89914 93207 NF1 1.098 0.09468
593 0008047 enzyme activator activity H000035_01 Apoptosis-associated speck-like protein containing a CARD NM_013258 71869 ASC 1.226 0.01397
594 0008047 enzyme activator activity H003757_01 MAP-kinase activating death domain U77352 82548 MADD 1.184 0.06185
595 0008047 enzyme activator activity H000390_01 Microsomal glutathione S-transferase 2 U77604 81874 MGST2 1.203 0.02993
596 0008047 enzyme activator activity H000411_01 Regulator of G-protein signalling 19 X91809 22698 RGS19 0.882 0.04412
597 0008047 enzyme activator activity H004200_01 Death effector filament-forming Ced-4-like apoptosis protein AB023143 104305 DEFCAP 0.943 0.34662
598 0008047 enzyme activator activity H000412_01 Regulator of G-protein signalling 14 AF037195 9347 RGS14 1.025 0.65334
599 0008047 enzyme activator activity H004224_01 Hypothetical protein FLJ10767 AK001629 25584 FLJ10767 1.127 0.09385
600 0008047 enzyme activator activity H004296_01 Matrix metalloproteinase 24 (membrane-inserted) AB021227 3743 MMP24 0.999 0.99235
601 0008047 enzyme activator activity H004551_01 Metalloprotease 1 (pitrilysin family) AK002061 260116 MP1 1.1 0.12264
602 0008047 enzyme activator activity H004598_01 Hypothetical protein PP1044 AF131825 7212 PP1044 1.269 0.01003
603 0008047 enzyme activator activity H000440_01 Regulator of G-protein signalling 3 U27655 82294 RGS3 1.032 0.6932
604 0008047 enzyme activator activity H000446_01 Proteasome (prosome, macropain) activator subunit 1 (PA28
alpha)		 L07633 75348 PSME1 0.898 0.05819
605 0008047 enzyme activator activity H004890_01 PDZ domain containing guanine nucleotide exchange factor(GEF)1 AB002311 154545 PDZ-GEF1 0.973 0.67067
606 0008047 enzyme activator activity H004895_01 Hypothetical protein FLJ11323 AK002185 25625 FLJ11323 1.069 0.2911
607 0008047 enzyme activator activity H000475_01 Apoptotic protease activating factor NM_013229 77579 APAF1 1.008 0.87839
608 0008047 enzyme activator activity H006228_01 Deleted in liver cancer 1 AL117604 8700 DLC1 0.916 0.21322
609 0008047 enzyme activator activity H006485_01 Protein kinase, interferon-inducible double stranded RNA
dependent activator		 AF072860 18571 PRKRA 0.901 0.10102
610 0008047 enzyme activator activity H006648_01 PTPL1-associated RhoGAP 1 U90920 70983 PARG1 1.094 0.45938
611 0008047 enzyme activator activity H006668_01 RAS p21 protein activator (GTPase activating protein) 3
(Ins(1,3,4,5)P4-binding protein)		 X89399 119274 RASA3 1.023 0.70325
612 0008047 enzyme activator activity H006707_01 Development and differentiation enhancing factor 2 AB007860 12802 DDEF2 1.221 0.01623
613 0008047 enzyme activator activity H006855_01 KIAA1108 protein AB029031 278586 KIAA1108 1.079 0.30292
614 0008047 enzyme activator activity H007032_01 BCL2/adenovirus E1B 19kD-interacting protein 2 U15173 155596 BNIP2 0.949 0.32291
615 0008047 enzyme activator activity H007037_01 Regulator of G-protein signalling 6 AF073920 3221 RGS6 1.115 0.19727
616 0008047 enzyme activator activity H000584_01 Regulator of G-protein signalling 4 U27768 227571 RGS4 0.92 0.29059
617 0008047 enzyme activator activity H007196_01 General transcription factor IIIC, polypeptide 4 (90kD) NM_012204 22302 GTF3C4 1.011 0.85743
618 0008047 enzyme activator activity H000587_01 Ubiquitin-activating enzyme E1-like L13852 16695 UBE1L 0.971 0.65943
619 0008047 enzyme activator activity H007392_01 ADP-ribosylation factor 5 M57567 77541 ARF5 1.029 0.52757
620 0008047 enzyme activator activity H007564_01 Caspase recruitment domain 4 NM_006092 19405 NOD1 0.94 0.28814
621 0008047 enzyme activator activity H007827_01 Rho guanine exchange factor (GEF) 11 AB002378 47822 ARHGEF11 0.963 0.50601
622 0008047 enzyme activator activity H008350_01 Myosin phosphatase, target subunit 2 AB007972 130760 MYPT2 0.895 0.27031
623 0008047 enzyme activator activity H008446_01 KIAA0167 gene product D79989 184884 KIAA0167 0.973 0.64609
624 0008047 enzyme activator activity H008518_01 Estrogen receptor binding site associated, antigen, 9 AB007619 9222 EBAG9 1.055 0.44919
625 0008047 enzyme activator activity H008553_01 Protein kinase, AMP-activated, alpha 1 catalytic subunit AB022017 9247 PRKAA1 1.089 0.15692
626 0008047 enzyme activator activity H000680_01 Active BCR-related gene U01147 118021 ABR 0.879 0.02186
627 0008047 enzyme activator activity H008771_01 MIL1 protein NM_015367 10267 MIL1 0.875 0.08726
628 0008047 enzyme activator activity H000687_01 Apolipoprotein C-II NM_000483 75615 APOC2 1.016 0.80834
629 0008047 enzyme activator activity H009484_01 G protein-coupled receptor kinase-interactor 1 NM_014030 318339 GIT1 1.067 0.32333
630 0008047 enzyme activator activity H009941_01 Rho GTPase activating protein 1 U62794 138860 ARHGAP1 1.013 0.88343
631 0008047 enzyme activator activity H010039_01 Tuberous sclerosis 2 X75621 90303 TSC2 0.954 0.5158
632 0008047 enzyme activator activity H010766_01 Glia maturation factor, gamma AB001993 5210 GMFG 1.179 0.13646
633 0008047 enzyme activator activity H010923_01 Regulator of G-protein signalling 11 NM_003834 65756 RGS11 0.905 0.17547
634 0008047 enzyme activator activity H011078_01 Chimerin (chimaerin) 1 X51408 169965 CHN1 0.769 0.00978
635 0008047 enzyme activator activity H011501_01 ADP-ribosylation factor 4 NM_001660 75290 ARF4 0.845 0.02658
636 0008047 enzyme activator activity H011986_01 DKFZP727I051 protein AL117478 239370 DKFZP727I051 1.08 0.28838
637 0008047 enzyme activator activity H011998_01 Centaurin-alpha 2 protein AJ272195 28802 HSA272195 0.999 0.9876
638 0008047 enzyme activator activity H012025_01 Homo sapiens cDNA FLJ10023 fis, clone HEMBA1000608,
moderately similar to HYPOTHETICAL PROTEIN KIAA0		 AK000885 306413 0.961 0.63648
639 0008047 enzyme activator activity H000887_01 Prosaposin (variant Gaucher disease and variant metachromatic
leukodystrophy)		 J03077 78575 PSAP 0.85 0.03087
640 0008047 enzyme activator activity H012654_01 Cdc42 effector protein 2 AF001436 12289 CEP2 0.859 0.08372
641 0008047 enzyme activator activity H012678_01 RalA binding protein 1 L42542 75447 RALBP1 0.945 0.30959
642 0008047 enzyme activator activity H013086_01 Oligophrenin 1 AJ001189 128824 OPHN1 1.059 0.43883
643 0008047 enzyme activator activity H013206_01 ADP-ribosylation factor GTPase activating protein 1 AF111847 13014 ARFGAP1 1.202 0.09399
644 0008047 enzyme activator activity H013355_01 Meningioma expressed antigen 6 (coiled-coil proline-rich) U94780 117242 MGEA6 0.918 0.15887
645 0008047 enzyme activator activity H013770_01 Colipase, pancreatic J02883 1340 CLPS 0.98 0.81059
646 0008047 enzyme activator activity H014008_01 Homo sapiens mRNA; cDNA DKFZp434P2235 (from clone
DKFZp434P2235); complete cds		 AL136860 105891 0.93 0.3587
647 0008047 enzyme activator activity H014216_01 Hypothetical protein similar to mouse Dnajl1 NM_022365 13015 DNAJL1 0.939 0.31485
648 0008047 enzyme activator activity H014530_01 Hypothetical protein FLJ22439 NM_024832 180040 FLJ22439 1.182 0.05692
649 0008047 enzyme activator activity H015517_01 Chromosome 6 open reading frame 9 NM_022107 288316 C6ORF9 1.12 0.0883
650 0008047 enzyme activator activity H015633_01 GM2 ganglioside activator protein NM_000405 289082 GM2A 1.007 0.91285
651 0008047 enzyme activator activity H000015_01 Dedicator of cyto-kinesis 1 D50857 82295 DOCK1 0.995 0.95
652 0008047 enzyme activator activity H001274_01 Regulator of G-protein signalling 2, 24kD L13463 78944 RGS2 0.911 0.12621
653 0015078 hydrogen ion transporter activity H001499_01 Ubiquinol-cytochrome c reductase hinge protein Y00764 73818 UQCRH 1.114 0.01812
654 0015078 hydrogen ion transporter activity H001510_01 NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD)
(NADH-coenzyme Q reductase)		 X61100 8248 NDUFS1 1.055 0.28624
655 0015078 hydrogen ion transporter activity H001513_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 (12kD,
B12)		 AF047183 109760 NDUFB3 1.102 0.0437
656 0015078 hydrogen ion transporter activity H001514_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4 (15kD,
B15)		 AF044957 227750 NDUFB4 1.058 0.18971
657 0015078 hydrogen ion transporter activity H001526_01 NADH dehydrogenase (ubiquinone) Fe-S protein 4 (18kD)
(NADH-coenzyme Q reductase)		 AF020351 10758 NDUFS4 1.029 0.52362
658 0015078 hydrogen ion transporter activity H001530_01 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
(14.5kD, B14.5b)		 AL050278 193313 NDUFC2 1 0.99825
659 0015078 hydrogen ion transporter activity H001540_01 NADH dehydrogenase (ubiquinone) Fe-S protein 5 (15kD)
(NADH-coenzyme Q reductase)		 AF047434 80595 NDUFS5 1.035 0.51566
660 0015078 hydrogen ion transporter activity H001544_01 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
(6kD, KFYI)		 AF047184 84549 NDUFC1 1.084 0.06377
661 0015078 hydrogen ion transporter activity H001551_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD,
B14)		 AF047182 274416 NDUFA6 1.088 0.09856
662 0015078 hydrogen ion transporter activity H001555_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7
(14.5kD, B14.5a)		 AF054178 19561 NDUFA7 0.999 0.99
663 0015078 hydrogen ion transporter activity H001563_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD,
B13)		 NM_005000 83916 NDUFA5 0.934 0.19767
664 0015078 hydrogen ion transporter activity H001564_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 (9kD,
B9)		 AF044955 198269 NDUFA3 0.979 0.63748
665 0015078 hydrogen ion transporter activity H001565_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD) AF087661 198271 NDUFA10 0.913 0.06739
666 0015078 hydrogen ion transporter activity H001566_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD,
AGGG)		 AF050639 198272 NDUFB2 1.036 0.45378
667 0015078 hydrogen ion transporter activity H001567_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8 (19kD,
ASHI)		 AF044958 198273 NDUFB8 1.025 0.54405
668 0015078 hydrogen ion transporter activity H001568_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10 (22kD,
PDSW)		 AF088991 198274 NDUFB10 1.039 0.30356
669 0015078 hydrogen ion transporter activity H001570_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 (17kD,
B17)		 AF035840 109646 NDUFB6 1.002 0.96713
670 0015078 hydrogen ion transporter activity H001573_01 NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) M22538 51299 NDUFV2 0.983 0.71504
671 0015078 hydrogen ion transporter activity H001574_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5 (16kD,
SGDH)		 AF047181 19236 NDUFB5 0.918 0.15934
672 0015078 hydrogen ion transporter activity H001576_01 NADH dehydrogenase (ubiquinone) Fe-S protein 2 (49kD)
(NADH-coenzyme Q reductase)		 AF050640 173611 NDUFS2 0.902 0.11184
673 0015078 hydrogen ion transporter activity H000185_01 ATP synthase, H+ transporting, mitochondrial F1 complex,
delta subunit		 X63422 89761 ATP5D 1.029 0.72891
674 0015078 hydrogen ion transporter activity H001580_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9 (39kD) L04490 75227 NDUFA9 0.979 0.66969
675 0015078 hydrogen ion transporter activity H002007_01 ATP synthase, H+ transporting, mitochondrial F1 complex,
alpha subunit, isoform 1, cardiac muscle		 D14710 155101 ATP5A1 0.963 0.52195
676 0015078 hydrogen ion transporter activity H002282_01 NADH dehydrogenase (ubiquinone) flavoprotein 1 (51kD) AF053070 7744 NDUFV1 1.092 0.11392
677 0015078 hydrogen ion transporter activity H003085_01 NADH dehydrogenase (ubiquinone) Fe-S protein 6 (13kD)
(NADH-coenzyme Q reductase)		 AF044959 49767 NDUFS6 1.006 0.88765
678 0015078 hydrogen ion transporter activity H003132_01 Nicotinamide nucleotide transhydrogenase U40490 18136 NNT 0.917 0.25595
679 0015078 hydrogen ion transporter activity H000388_01 ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit F6		 AL110183 73851 ATP5J 1.045 0.27907
680 0015078 hydrogen ion transporter activity H004736_01 Cytochrome c oxidase subunit VIIb Z14244 75752 COX7B 1.06 0.26006
681 0015078 hydrogen ion transporter activity H005548_01 ATP synthase, H+ transporting, mitochondrial F1 complex, O
subunit (oligomycin sensitivity conferrin		 X83218 76572 ATP5O 1.045 0.37569
682 0015078 hydrogen ion transporter activity H005788_01 Vacuolar proton pump delta polypeptide NM_015994 272630 VATD 0.851 0.06815
683 0015078 hydrogen ion transporter activity H005994_01 ATPase, H+ transporting, lysosomal (vacuolar proton pump),
beta polypeptide, 56/58kD, isoform 2		 L35249 1697 ATP6B2 0.927 0.20852
684 0015078 hydrogen ion transporter activity H006153_01 ATPase, vacuolar, 14 kD D49400 78089 ATP6S14 1.02 0.7878
685 0015078 hydrogen ion transporter activity H006240_01 Solute carrier family 9 (sodium/hydrogen exchanger), isoform 5 AF111173 198295 SLC9A5 1.092 0.21488
686 0015078 hydrogen ion transporter activity H006293_01 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD D89052 7476 ATP6F 0.919 0.12836
687 0015078 hydrogen ion transporter activity H006320_01 ATP synthase, H+ transporting, mitochondrial F1 complex,
gamma polypeptide 1		 D16562 155433 ATP5C1 1.036 0.56223
688 0015078 hydrogen ion transporter activity H006566_01 Surfeit 1 Z35093 3196 SURF1 1.012 0.78851
689 0015078 hydrogen ion transporter activity H007321_01 Cytochrome c oxidase subunit Va M22760 181028 COX5A 1.029 0.61125
690 0015078 hydrogen ion transporter activity H007339_01 ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit e		 D50371 85539 ATP5I 1.09 0.05197
691 0015078 hydrogen ion transporter activity H000596_01 T-cell, immune regulator 1 U45285 46465 TCIRG1 1.007 0.89507
692 0015078 hydrogen ion transporter activity H007379_01 Ubiquinol-cytochrome c reductase core protein I L16842 119251 UQCRC1 1.088 0.08601
693 0015078 hydrogen ion transporter activity H007828_01 ATP synthase, H+ transporting, mitochondrial F1F0, subunit d AF087135 64593 ATP5JD 1.048 0.29166
694 0015078 hydrogen ion transporter activity H008257_01 CGI-11 protein NM_015941 19575 LOC51606 0.916 0.08209
695 0015078 hydrogen ion transporter activity H008343_01 ATP synthase, H+ transporting, mitochondrial F1 complex,
epsilon subunit		 NM_006886 177530 ATP5E 0.937 0.20022
696 0015078 hydrogen ion transporter activity H008594_01 CGI-39 protein; cell death-regulatory protein GRIM19 NM_015965 279574 LOC51079 0.951 0.32588
697 0015078 hydrogen ion transporter activity H008752_01 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase) D50487 171872 DDX8 1.107 0.13986
698 0015078 hydrogen ion transporter activity H009190_01 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD X76228 77805 ATP6E 0.882 0.09289
699 0015078 hydrogen ion transporter activity H009563_01 Ubiquinol-cytochrome c reductase binding protein M22348 131255 UQCRB 1.046 0.28769
700 0015078 hydrogen ion transporter activity H009699_01 ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit c (subunit 9) isoform 3		 U09813 429 ATP5G3 1.077 0.21392
701 0015078 hydrogen ion transporter activity H010384_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 (19kD,
PGIV)		 NM_014222 31547 NDUFA8 0.984 0.70072
702 0015078 hydrogen ion transporter activity H000765_01 Cytochrome b-5 M22976 83834 CYB5 0.82 0.01254
703 0015078 hydrogen ion transporter activity H010491_01 Cytochrome c oxidase subunit VIIa polypeptide 2 like AB007618 30888 COX7A2L 1.109 0.09893
704 0015078 hydrogen ion transporter activity H010619_01 Ubiquinol-cytochrome c reductase core protein II J04973 173554 UQCRC2 0.977 0.62446
705 0015078 hydrogen ion transporter activity H010932_01 ATP synthase, H+ transporting, mitochondrial F1F0, subunit g AL050277 107476 ATP5JG 1.071 0.142
706 0015078 hydrogen ion transporter activity H010960_01 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD Y15286 24322 ATP6H 0.879 0.02487
707 0015078 hydrogen ion transporter activity H011203_01 Solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 AF030409 62185 SLC9A6 1.012 0.79956
708 0015078 hydrogen ion transporter activity H011537_01 COX11 (yeast) homolog, cytochrome c oxidase assembly protein AF044321 241515 COX11 0.976 0.7547
709 0015078 hydrogen ion transporter activity H011753_01 ATPase, H+ transporting, lysosomal (vacuolar proton pump) 42kD AK000064 86905 ATP6C 1.003 0.97556
710 0015078 hydrogen ion transporter activity H000085_01 Cytochrome c oxidase subunit VIb X13923 174031 COX6B 0.988 0.76171
711 0015078 hydrogen ion transporter activity H012749_01 NADH dehydrogenase (ubiquinone) Fe-S protein 8 (23kD)
(NADH-coenzyme Q reductase)		 AK002110 90443 NDUFS8 1.109 0.16723
712 0015078 hydrogen ion transporter activity H013186_01 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9 (22kD,
B22)		 NM_005005 15977 NDUFB9 1.048 0.32858
713 0015078 hydrogen ion transporter activity H001053_01 Solute carrier family 9 (sodium/hydrogen exchanger), isoform
1 (antiporter, Na+/H+, amiloride		 S68616 170222 SLC9A1 0.96 0.34393
714 0015078 hydrogen ion transporter activity H015293_01 Ubiquinol-cytochrome c reductase complex (7.2 kD) NM_013387 284292 HSPC051 1.078 0.13086
715 0015078 hydrogen ion transporter activity H001069_01 ATPase, H+ transporting, lysosomal (vacuolar proton pump)
non-catalytic accessory protein 1A (110/11		 Z71460 267871 ATP6N1A 0.876 0.02946
716 0015078 hydrogen ion transporter activity H001097_01 Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 U28043 123044 SLC9A3 0.903 0.1196
717 0015078 hydrogen ion transporter activity H015976_01 Homo sapiens clone 023e08 My032 protein mRNA, complete cds AF061735 307099 1.028 0.60769
718 0015078 hydrogen ion transporter activity H016294_01 Cytochrome c oxidase subunit VIIc NM_001867 3462 COX7C 1.009 0.84276
719 0015078 hydrogen ion transporter activity H016310_01 Low molecular mass ubiquinone-binding protein (9.5kD) NM_014402 3709 QP-C 1.058 0.19398
720 0015078 hydrogen ion transporter activity H016350_01 13kDa differentiation-associated protein NM_018838 44163 LOC55967 1.189 0.00368
721 0015078 hydrogen ion transporter activity H016396_01 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 (9kD,
MLRQ)		 NM_002489 50098 NDUFA4 0.92 0.16861
722 0015078 hydrogen ion transporter activity H016552_01 Ubiquinol-cytochrome c reductase (6.4kD) subunit NM_006830 8372 UQCR 1.005 0.92218
723 0015078 hydrogen ion transporter activity H000121_01 ATP synthase, H+ transporting, mitochondrial F1 complex, beta
polypeptide		 D00022 25 ATP5B 1.07 0.30166
724 0015078 hydrogen ion transporter activity H000125_01 ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit b, isoform 1		 X60221 81634 ATP5F1 1.008 0.90231
725 0015078 hydrogen ion transporter activity H001301_01 Activating transcription factor 7 X52943 55888 ATF7 0.926 0.12647