Pathway Comparison – Page Four
| Order | Broad Pathway | Pathway description | Unique id | Annotations | Description | Clone | GB acc | UG cluster | Gene symbol | Defined gene lists | Parametric p-value | Geometric mean of ratios (class Disease /class Normal ) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2290 | drug_resistance_and_metabolism_h | BioCarta | H003283_01 | Info | Topoisomerase (DNA) II alpha (170kD) | H003283_01 | J04088 (external link) | 156346 | TOP2A (external link) | Apoptotic DNA fragmentation and tissue homeostasis, DNA_adducts, DNA_damage, DNA_replication | 0.0203748 | 0.733 |
| 2291 | drug_resistance_and_metabolism_h | BioCarta | H002533_01 | Info | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | H002533_01 | AF076622 (external link) | 274260 | ABCC6 (external link) | 0.0229826 | 1.478 | |
| 2292 | drug_resistance_and_metabolism_h | BioCarta | H003410_01 | Info | Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | H003410_01 | U26727 (external link) | 1174 | CDKN2A (external link) | Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0245577 | 0.782 |
| 2293 | drug_resistance_and_metabolism_h | BioCarta | H002789_01 | Info | Tumor protein p53 (Li-Fraumeni syndrome) | H002789_01 | NM_000546 (external link) | 1846 | TP53 (external link) | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc | 0.0273242 | 1.207 |
| 2294 | drug_resistance_and_metabolism_h | BioCarta | H003759_01 | Info | Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | H003759_01 | U40343 (external link) | 29656 | CDKN2D (external link) | Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation | 0.0311312 | 1.253 |
| 2295 | drug_resistance_and_metabolism_h | BioCarta | H002149_01 | Info | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | H002149_01 | U03106 (external link) | 179665 | CDKN1A (external link) | ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc | 0.0349766 | 1.236 |
| 2296 | drug_resistance_and_metabolism_h | BioCarta | H002424_01 | Info | Bleomycin hydrolase | H002424_01 | X92106 (external link) | 78943 | BLMH (external link) | immunology, pharmacology | 0.0414602 | 0.81 |
| 2297 | drug_resistance_and_metabolism_h | BioCarta | H007820_01 | Info | Retinoic acid receptor-beta associated open reading frame | H007820_01 | S82362 (external link) | 1938 | LOC51036 (external link) | Control of Gene Expression by Vitamin D Receptor, DNA_adducts, DNA_damage, gene_regulation, transcription | 0.0421365 | 0.794 |
| 2298 | drug_resistance_and_metabolism_h | BioCarta | H003156_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide | H003156_01 | M83221 (external link) | 858 | RELB (external link) | tsonc | 0.0527226 | 1.209 |
| 2299 | drug_resistance_and_metabolism_h | BioCarta | H007892_01 | Info | Cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 | H007892_01 | M61854 (external link) | 198501 | CYP2C19 (external link) | Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism, pharmacology | 0.0560255 | 0.801 |
| 2300 | drug_resistance_and_metabolism_h | BioCarta | H003713_01 | Info | Topoisomerase (DNA) II beta (180kD) | H003713_01 | X68060 (external link) | 75248 | TOP2B (external link) | Control of Gene Expression by Vitamin D Receptor, DNA_adducts, DNA_damage, gene_regulation, transcription | 0.075384 | 0.83 |
| 2301 | drug_resistance_and_metabolism_h | BioCarta | H002473_01 | Info | Insulin-like growth factor 1 receptor | H002473_01 | NM_000875 (external link) | 239176 | IGF1R (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology | 0.079692 | 1.158 |
| 2302 | drug_resistance_and_metabolism_h | BioCarta | H003600_01 | Info | Epoxide hydrolase 2, cytoplasmic | H003600_01 | L05779 (external link) | 113 | EPHX2 (external link) | Tetrachloroethene degradation, immunology, metabolism, pharmacology | 0.092835 | 0.858 |
| 2303 | drug_resistance_and_metabolism_h | BioCarta | H002323_01 | Info | Cyclin E1 | H002323_01 | M74093 (external link) | 9700 | CCNE1 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle | 0.1107382 | 0.884 |
| 2304 | drug_resistance_and_metabolism_h | BioCarta | H003376_01 | Info | Aryl hydrocarbon receptor nuclear translocator | H003376_01 | M69238 (external link) | 166172 | ARNT (external link) | Ahr Signal Transduction Pathway, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, immunology | 0.1249479 | 1.133 |
| 2305 | drug_resistance_and_metabolism_h | BioCarta | H014546_01 | Info | Peptidylprolyl isomerase A (cyclophilin A) | H014546_01 | NM_021130 (external link) | 182937 | PPIA (external link) | IL-2 Receptor Beta Chain in T cell Activation | 0.129858 | 1.176 |
| 2306 | drug_resistance_and_metabolism_h | BioCarta | H003023_01 | Info | Dihydrofolate reductase | H003023_01 | NM_000791 (external link) | 83765 | DHFR (external link) | Cell Cycle: G1/S Check Point , Folate biosynthesis, One carbon pool by folate, immunology, pharmacology | 0.1336155 | 0.862 |
| 2307 | drug_resistance_and_metabolism_h | BioCarta | H003550_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | H003550_01 | S76638 (external link) | 73090 | NFKB2 (external link) | gene_regulation, immunology, transcription, tsonc | 0.1593331 | 1.165 |
| 2308 | drug_resistance_and_metabolism_h | BioCarta | H001986_01 | Info | Aryl hydrocarbon receptor | H001986_01 | NM_001621 (external link) | 170087 | AHR (external link) | Ahr Signal Transduction Pathway, gene_regulation, immunology, transcription | 0.1792938 | 1.117 |
| 2309 | drug_resistance_and_metabolism_h | BioCarta | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 (external link) | 79070 | MYC (external link) | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 2310 | drug_resistance_and_metabolism_h | BioCarta | H003810_01 | Info | Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | H003810_01 | X02317 (external link) | 75428 | SOD1 (external link) | Cardiac Protection Against ROS , Free Radical Induced Apoptosis, immunology, pharmacology | 0.1871555 | 1.13 |
| 2311 | drug_resistance_and_metabolism_h | BioCarta | H003242_01 | Info | Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pig | H003242_01 | M31899 (external link) | 77929 | ERCC3 (external link) | CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, DNA_damage, DNA_replication, immunology | 0.2157492 | 0.873 |
| 2312 | drug_resistance_and_metabolism_h | BioCarta | H003042_01 | Info | BCL2-like 1 | H003042_01 | Z23115 (external link) | 305890 | BCL2L1 (external link) | Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology | 0.2336065 | 1.143 |
| 2313 | drug_resistance_and_metabolism_h | BioCarta | H003605_01 | Info | BCL2-associated X protein | H003605_01 | L22474 (external link) | 159428 | BAX (external link) | Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology | 0.253339 | 0.907 |
| 2314 | drug_resistance_and_metabolism_h | BioCarta | H003514_01 | Info | Cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 | H003514_01 | M55053 (external link) | 1361 | CYP1A2 (external link) | Mechanism of Acetaminophen Activity and Toxicity, Nuclear Receptors in Lipid Metabolism and Toxicity, Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism, immunology, pharmacology | 0.2704204 | 1.089 |
| 2315 | drug_resistance_and_metabolism_h | BioCarta | H011468_01 | Info | ATP-binding cassette, sub-family G (WHITE), member 2 | H011468_01 | AF103796 (external link) | 194720 | ABCG2 (external link) | 0.2713892 | 0.876 | |
| 2316 | drug_resistance_and_metabolism_h | BioCarta | H002577_01 | Info | MutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2) | H002577_01 | U07418 (external link) | 57301 | MLH1 (external link) | DNA_damage, DNA_replication, tsonc | 0.2947975 | 0.894 |
| 2317 | drug_resistance_and_metabolism_h | BioCarta | H003016_01 | Info | Insulin-like growth factor 2 receptor | H003016_01 | Y00285 (external link) | 76473 | IGF2R (external link) | immunology | 0.3174469 | 1.143 |
| 2318 | drug_resistance_and_metabolism_h | BioCarta | H001999_01 | Info | Cyclin D1 (PRAD1: parathyroid adenomatosis 1) | H001999_01 | X59798 (external link) | 82932 | CCND1 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc | 0.3215316 | 0.898 |
| 2319 | drug_resistance_and_metabolism_h | BioCarta | H002702_01 | Info | Retinoic acid receptor, gamma | H002702_01 | M38258 (external link) | 1497 | RARG (external link) | Nuclear Receptors in Lipid Metabolism and Toxicity, development, gene_regulation, transcription | 0.4297075 | 1.087 |
| 2320 | drug_resistance_and_metabolism_h | BioCarta | H002294_01 | Info | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | H002294_01 | X78338 (external link) | 89433 | ABCC1 (external link) | Multi-Drug Resistance Factors | 0.4691659 | 0.928 |
| 2321 | drug_resistance_and_metabolism_h | BioCarta | H002907_01 | Info | Retinoic acid receptor, alpha | H002907_01 | X06614 (external link) | 250505 | RARA (external link) | Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development | 0.4825926 | 1.084 |
| 2322 | drug_resistance_and_metabolism_h | BioCarta | H000149_01 | Info | Epoxide hydrolase 1, microsomal (xenobiotic) | H000149_01 | NM_000120 (external link) | 89649 | EPHX1 (external link) | Eicosanoid Metabolism, Tetrachloroethene degradation, immunology, metabolism, pharmacology | 0.512274 | 0.938 |
| 2323 | drug_resistance_and_metabolism_h | BioCarta | H001952_01 | Info | Ribosomal protein L13a | H001952_01 | X56932 (external link) | 119122 | RPL13A (external link) | 0.565051 | 1.059 | |
| 2324 | drug_resistance_and_metabolism_h | BioCarta | H006635_01 | Info | Homo sapiens clone 23607 mRNA sequence | H006635_01 | AF038181 (external link) | 167825 | ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc | 0.6181322 | 1.041 | |
| 2325 | drug_resistance_and_metabolism_h | BioCarta | H002777_01 | Info | Cytochrome P450, subfamily IIE (ethanol-inducible) | H002777_01 | J02625 (external link) | 75183 | CYP2E (external link) | Mechanism of Acetaminophen Activity and Toxicity, Nuclear Receptors in Lipid Metabolism and Toxicity, Fatty acid metabolism, gamma-Hexachlorocyclohexane degradation, Tryptophan metabolism | 0.6229802 | 0.953 |
| 2326 | drug_resistance_and_metabolism_h | BioCarta | H003538_01 | Info | Actin, beta | H003538_01 | NM_001101 (external link) | 288061 | ACTB (external link) | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes | 0.6253266 | 0.956 |
| 2327 | drug_resistance_and_metabolism_h | BioCarta | H013267_01 | Info | Homo sapiens clone R2 ErbB-3 R2 (c-erbB-3) mRNA, partial CDS | H013267_01 | U88358 (external link) | 306251 | Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of ERBB2 in Signal Transduction and Oncology, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.6380266 | 1.054 | |
| 2328 | drug_resistance_and_metabolism_h | BioCarta | H001853_01 | Info | Cellular retinoic acid-binding protein 1 | H001853_01 | S74445 (external link) | 7678 | CRABP1 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.6817674 | 0.954 |
| 2329 | drug_resistance_and_metabolism_h | BioCarta | H002094_01 | Info | Thymidylate synthetase | H002094_01 | X02308 (external link) | 82962 | TYMS (external link) | One carbon pool by folate, Pyrimidine metabolism, metabolism, pharmacology | 0.6945693 | 1.041 |
| 2330 | drug_resistance_and_metabolism_h | BioCarta | H002029_01 | Info | V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 | H002029_01 | M34309 (external link) | 199067 | ERBB3 (external link) | Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of ERBB2 in Signal Transduction and Oncology, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.7019431 | 1.035 |
| 2331 | drug_resistance_and_metabolism_h | BioCarta | H003542_01 | Info | V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene | H003542_01 | M11730 (external link) | 323910 | ERBB2 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc | 0.7160857 | 1.031 |
| 2332 | drug_resistance_and_metabolism_h | BioCarta | H003482_01 | Info | Catechol-O-methyltransferase | H003482_01 | NM_000754 (external link) | 240013 | COMT (external link) | Tyrosine metabolism, behavior, immunology | 0.777803 | 1.026 |
| 2333 | drug_resistance_and_metabolism_h | BioCarta | H006841_01 | Info | Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) | H006841_01 | AL049301 (external link) | 278577 | Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology | 0.7810094 | 0.98 | |
| 2334 | drug_resistance_and_metabolism_h | BioCarta | H000245_01 | Info | Peroxisome proliferative activated receptor, gamma | H000245_01 | L40904 (external link) | 100724 | PPARG (external link) | Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome | 0.7837641 | 0.944 |
| 2335 | drug_resistance_and_metabolism_h | BioCarta | H003772_01 | Info | Xeroderma pigmentosum, complementation group C | H003772_01 | D21089 (external link) | 320 | XPC (external link) | DNA_damage, immunology | 0.7950726 | 0.977 |
| 2336 | drug_resistance_and_metabolism_h | BioCarta | H003355_01 | Info | Retinoid X receptor, gamma | H003355_01 | U38480 (external link) | 26550 | RXRG (external link) | development | 0.8348881 | 1.017 |
| 2337 | drug_resistance_and_metabolism_h | BioCarta | H001977_01 | Info | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | H001977_01 | AF085692 (external link) | 90786 | ABCC3 (external link) | Multi-Drug Resistance Factors, Nuclear Receptors in Lipid Metabolism and Toxicity | 0.8363263 | 1.021 |
| 2338 | drug_resistance_and_metabolism_h | BioCarta | H002350_01 | Info | Peroxisome proliferative activated receptor, alpha | H002350_01 | L02932 (external link) | 998 | PPARA (external link) | Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway | 0.8655149 | 1.015 |
| 2339 | drug_resistance_and_metabolism_h | BioCarta | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 (external link) | 83428 | NFKB1 (external link) | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 2340 | drug_resistance_and_metabolism_h | BioCarta | H002373_01 | Info | MutS (E. coli) homolog 3 | H002373_01 | U61981 (external link) | 42674 | MSH3 (external link) | DNA_damage, immunology | 0.8910817 | 0.986 |
| 2341 | drug_resistance_and_metabolism_h | BioCarta | H015889_01 | Info | BCL2-like 1 | H015889_01 | NM_001191 (external link) | 305890 | BCL2L1 (external link) | Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology | 0.996743 | 1.001 |
| 2342 | il10Pathway_h | BioCarta | H002638_01 | Info | Interleukin 10 receptor, beta | H002638_01 | Z17227 (external link) | 173936 | IL10RB (external link) | immunology | 0.0028797 | 1.503 |
| 2343 | il10Pathway_h | BioCarta | H003233_01 | Info | Biliverdin reductase A | H003233_01 | X93086 (external link) | 81029 | BLVRA (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, IL-10 Anti-inflammatory Signaling Pathway, Porphyrin and chlorophyll metabolism | 0.0063489 | 1.363 |
| 2344 | il10Pathway_h | BioCarta | H002933_01 | Info | Biliverdin reductase B (flavin reductase (NADPH)) | H002933_01 | D32143 (external link) | 76289 | BLVRB (external link) | Porphyrin and chlorophyll metabolism | 0.0542266 | 1.306 |
| 2345 | il10Pathway_h | BioCarta | H002710_01 | Info | Interleukin 10 | H002710_01 | M57627 (external link) | 193717 | IL10 (external link) | Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, IL-10 Anti-inflammatory Signaling Pathway, immunology | 0.0986725 | 0.876 |
| 2346 | il10Pathway_h | BioCarta | H003781_01 | Info | Interleukin 10 receptor, alpha | H003781_01 | U00672 (external link) | 327 | IL10RA (external link) | IL-10 Anti-inflammatory Signaling Pathway, IL22 Soluble Receptor Signaling Pathway , immunology | 0.1863247 | 1.157 |
| 2347 | il10Pathway_h | BioCarta | H001349_01 | Info | Janus kinase 1 (a protein tyrosine kinase) | H001349_01 | M64174 (external link) | 50651 | JAK1 (external link) | EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.2754104 | 1.129 |
| 2348 | il10Pathway_h | BioCarta | H003110_01 | Info | Interleukin 6 (interferon, beta 2) | H003110_01 | X04430 (external link) | 93913 | IL6 (external link) | Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology | 0.680804 | 1.036 |
| 2349 | rbPathway_h | BioCarta | H003112_01 | Info | Retinoblastoma 1 (including osteosarcoma) | H003112_01 | L41870 (external link) | 75770 | RB1 (external link) | BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0008596 | 0.674 |
| 2350 | rbPathway_h | BioCarta | H002412_01 | Info | Cyclin-dependent kinase 2 | H002412_01 | M68520 (external link) | 19192 | CDK2 (external link) | CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction | 0.0040171 | 0.711 |
| 2351 | rbPathway_h | BioCarta | H002304_01 | Info | Cell division cycle 25B | H002304_01 | S78187 (external link) | 153752 | CDC25B (external link) | 0.0167858 | 0.8 | |
| 2352 | rbPathway_h | BioCarta | H003739_01 | Info | Cell division cycle 2, G1 to S and G2 to M | H003739_01 | X05360 (external link) | 184572 | CDC2 (external link) | Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle | 0.0222229 | 0.733 |
| 2353 | rbPathway_h | BioCarta | H002789_01 | Info | Tumor protein p53 (Li-Fraumeni syndrome) | H002789_01 | NM_000546 (external link) | 1846 | TP53 (external link) | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc | 0.0273242 | 1.207 |
| 2354 | rbPathway_h | BioCarta | H003048_01 | Info | Cell division cycle 25C | H003048_01 | M34065 (external link) | 656 | CDC25C (external link) | How Progesterone Initiates the Oocyte Maturation, Regulation of cell cycle progression by Plk3, cell_cycle, cell_signaling | 0.1856754 | 1.116 |
| 2355 | rbPathway_h | BioCarta | H007143_01 | Info | Hypothetical protein FLJ10883 | H007143_01 | AB028973 (external link) | 184628 | FLJ10883 (external link) | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage | 0.2391265 | 0.908 |
| 2356 | rbPathway_h | BioCarta | H008573_01 | Info | Myelin transcription factor 1 | H008573_01 | M96980 (external link) | 279562 | MYT1 (external link) | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage | 0.3193113 | 1.107 |
| 2357 | rbPathway_h | BioCarta | H002782_01 | Info | Wee1+ (S. pombe) homolog | H002782_01 | X62048 (external link) | 75188 | WEE1 (external link) | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology | 0.4033875 | 1.142 |
| 2358 | mprPathway_h | BioCarta | H003415_01 | Info | Protein kinase, cAMP-dependent, catalytic, beta | H003415_01 | M34181 (external link) | 87773 | PRKACB (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0048904 | 0.647 |
| 2359 | mprPathway_h | BioCarta | H002890_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 1 | H002890_01 | L07597 (external link) | 149957 | RPS6KA1 (external link) | Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system | 0.0138896 | 1.42 |
| 2360 | mprPathway_h | BioCarta | H003739_01 | Info | Cell division cycle 2, G1 to S and G2 to M | H003739_01 | X05360 (external link) | 184572 | CDC2 (external link) | Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle | 0.0222229 | 0.733 |
| 2361 | mprPathway_h | BioCarta | H002371_01 | Info | Cyclin B1 | H002371_01 | M25753 (external link) | 23960 | CCNB1 (external link) | Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle | 0.037756 | 0.797 |
| 2362 | mprPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 (external link) | 861 | MAPK3 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 2363 | mprPathway_h | BioCarta | H000398_01 | Info | Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 | H000398_01 | U49070 (external link) | 161362 | PIN1 (external link) | How Progesterone Initiates the Oocyte Maturation | 0.1163659 | 1.163 |
| 2364 | mprPathway_h | BioCarta | H003048_01 | Info | Cell division cycle 25C | H003048_01 | M34065 (external link) | 656 | CDC25C (external link) | How Progesterone Initiates the Oocyte Maturation, Regulation of cell cycle progression by Plk3, cell_cycle, cell_signaling | 0.1856754 | 1.116 |
| 2365 | mprPathway_h | BioCarta | H007143_01 | Info | Hypothetical protein FLJ10883 | H007143_01 | AB028973 (external link) | 184628 | FLJ10883 (external link) | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage | 0.2391265 | 0.908 |
| 2366 | mprPathway_h | BioCarta | H001698_01 | Info | Protein kinase, cAMP-dependent, regulatory, type II, alpha | H001698_01 | X14968 (external link) | 289075 | PRKAR2A (external link) | AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation | 0.2569617 | 1.125 |
| 2367 | mprPathway_h | BioCarta | H008573_01 | Info | Myelin transcription factor 1 | H008573_01 | M96980 (external link) | 279562 | MYT1 (external link) | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage | 0.3193113 | 1.107 |
| 2368 | mprPathway_h | BioCarta | H013009_01 | Info | Adenylyl cyclase-associated protein | H013009_01 | L12168 (external link) | 104125 | CAP (external link) | 0.4133824 | 1.094 | |
| 2369 | mprPathway_h | BioCarta | H000645_01 | Info | Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | H000645_01 | M33336 (external link) | 183037 | PRKAR1A (external link) | Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction | 0.4305614 | 0.935 |
| 2370 | mprPathway_h | BioCarta | H000460_01 | Info | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | H000460_01 | AL049933 (external link) | 203862 | GNAI1 (external link) | Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Bioactive Peptide Induced Signaling Pathway, CXCR4 Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Phospholipids as signaling intermediaries, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, cell_signaling, signal_transduction | 0.7235673 | 1.046 |
| 2371 | mprPathway_h | BioCarta | H006522_01 | Info | Neuroendocrine secretory protein 55 | H006522_01 | AF105253 (external link) | 113368 | NESP55 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Attenuation of GPCR Signaling, CCR3 signaling in Eosinophils, ChREBP regulation by carbohydrates and cAMP, Corticosteroids and cardioprotection, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, Erk1/Erk2 Mapk Signaling pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Phospholipase C-epsilon pathway, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Transcription factor CREB and its extracellular signals | 0.7456375 | 1.036 |
| 2372 | S1P_Signaling_h | BioCarta | H000632_01 | Info | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | H000632_01 | M27543 (external link) | 73799 | GNAI3 (external link) | 4.65e-05 | 0.599 | |
| 2373 | S1P_Signaling_h | BioCarta | H005429_01 | Info | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | H005429_01 | X04828 (external link) | 77269 | GNAI2 (external link) | 0.0105146 | 1.325 | |
| 2374 | S1P_Signaling_h | BioCarta | H001062_01 | Info | N-acylsphingosine amidohydrolase (acid ceramidase) | H001062_01 | U70063 (external link) | 75811 | ASAH (external link) | Perou’s – Intrinsic- Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … | 0.0187984 | 1.357 |
| 2375 | S1P_Signaling_h | BioCarta | H016134_01 | Info | V-akt murine thymoma viral oncogene homolog 2 | H016134_01 | NM_001626 (external link) | 326445 | AKT2 (external link) | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.0530988 | 1.287 |
| 2376 | S1P_Signaling_h | BioCarta | H002588_01 | Info | Mitogen-activated protein kinase 7 | H002588_01 | U29725 (external link) | 3080 | MAPK7 (external link) | Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), MAP Kinase Signaling Pathway, Role of Erk5 in Neuronal Survival, Phosphatidylinositol signaling system | 0.0614441 | 0.811 |
| 2377 | S1P_Signaling_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 (external link) | 861 | MAPK3 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 2378 | S1P_Signaling_h | BioCarta | H002346_01 | Info | Phospholipase C, beta 2 | H002346_01 | M95678 (external link) | 994 | PLCB2 (external link) | Inositol phosphate metabolism, Phosphatidylinositol signaling system | 0.158235 | 1.161 |
| 2379 | S1P_Signaling_h | BioCarta | H015734_01 | Info | Sphingosine kinase type 2 isoform | H015734_01 | AL136701 (external link) | 301305 | SPHK2 (external link) | 0.215668 | 1.15 | |
| 2380 | S1P_Signaling_h | BioCarta | H008919_01 | Info | Endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | H008919_01 | AF034780 (external link) | 202672 | EDG5 (external link) | 0.251348 | 1.101 | |
| 2381 | S1P_Signaling_h | BioCarta | H003497_01 | Info | V-akt murine thymoma viral oncogene homolog 2 | H003497_01 | M77198 (external link) | 326445 | AKT2 (external link) | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.3314111 | 0.872 |
| 2382 | S1P_Signaling_h | BioCarta | H008328_01 | Info | Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 | H008328_01 | AF233365 (external link) | 154210 | EDG1 (external link) | Phospholipids as signaling intermediaries, immunology | 0.3391872 | 0.905 |
| 2383 | S1P_Signaling_h | BioCarta | H001368_01 | Info | Phosphoinositide-3-kinase, class 2, beta polypeptide | H001368_01 | Y11312 (external link) | 132463 | PIK3C2B (external link) | Phosphatidylinositol signaling system | 0.5573946 | 0.949 |
| 2384 | S1P_Signaling_h | BioCarta | H016485_01 | Info | Sphingosine kinase 1 | H016485_01 | NM_021972 (external link) | 68061 | SPHK1 (external link) | Phospholipids as signaling intermediaries, Glycosphingolipid metabolism | 0.586652 | 1.06 |
| 2385 | S1P_Signaling_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 (external link) | 71816 | AKT1 (external link) | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 2386 | S1P_Signaling_h | BioCarta | H000460_01 | Info | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | H000460_01 | AL049933 (external link) | 203862 | GNAI1 (external link) | Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Bioactive Peptide Induced Signaling Pathway, CXCR4 Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Phospholipids as signaling intermediaries, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, cell_signaling, signal_transduction | 0.7235673 | 1.046 |
| 2387 | S1P_Signaling_h | BioCarta | H002757_01 | Info | Mitogen-activated protein kinase 6 | H002757_01 | X80692 (external link) | 271980 | MAPK6 (external link) | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.7279385 | 1.033 |
| 2388 | S1P_Signaling_h | BioCarta | H003773_01 | Info | Mitogen-activated protein kinase 4 | H003773_01 | X59727 (external link) | 269222 | MAPK4 (external link) | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.91886 | 1.013 |
| 2389 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H001185_01 | Info | Arylsulfatase A | H001185_01 | NM_000487 (external link) | 88251 | ARSA (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Glycosphingolipid metabolism, immunology | 0.0075221 | 1.385 |
| 2390 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H006143_01 | Info | UDP-Gal:beta GlcNAc beta 1,3-galactosyltransferase, polypeptide 4 | H006143_01 | AB026730 (external link) | 21495 | B3GALT4 (external link) | Ganglioside biosynthesis | 0.0084255 | 1.351 |
| 2391 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H001062_01 | Info | N-acylsphingosine amidohydrolase (acid ceramidase) | H001062_01 | U70063 (external link) | 75811 | ASAH (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … | 0.0187984 | 1.357 |
| 2392 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H010686_01 | Info | Human abnormal beta-hexosaminidase alpha chain (HEXA) mRNA, partial CDS | H010686_01 | J04178 (external link) | 166299 | Aminosugars metabolism, Globoside metabolism, Glycosaminoglycan degradation, N-Glycan degradation, immunology | 0.0245913 | 1.262 | |
| 2393 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H002064_01 | Info | Galactosidase, beta 1 | H002064_01 | M34423 (external link) | 79222 | GLB1 (external link) | Galactose metabolism, Glycerolipid metabolism, Glycosaminoglycan degradation, Glycosphingolipid metabolism, N-Glycan degradation | 0.0569698 | 0.805 |
| 2394 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H000076_01 | Info | UDP-glucose ceramide glucosyltransferase | H000076_01 | D50840 (external link) | 152601 | UGCG (external link) | Glycosphingolipid metabolism | 0.2145948 | 0.879 |
| 2395 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H008567_01 | Info | Sialidase 1 (lysosomal sialidase) | H008567_01 | AF040958 (external link) | 118721 | NEU1 (external link) | Glycosphingolipid metabolism, N-Glycan degradation | 0.2301846 | 0.878 |
| 2396 | MAP00600_Sphingoglycolipid_metabolism_h | GenMAPP (external link) | H014980_01 | Info | Glucosidase, beta; acid (includes glucosylceramidase) | H014980_01 | NM_000157 (external link) | 282997 | GBA (external link) | Cyanoamino acid metabolism, Glycosphingolipid metabolism, Starch and sucrose metabolism, Stilbene, coumarine and lignin biosynthesis, immunology | 0.9305051 | 0.99 |
| 2397 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H008949_01 | Info | Hypothetical protein | H008949_01 | AF151024 (external link) | 122492 | LOC51237 (external link) | 0.0022423 | 1.318 | |
| 2398 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H000570_01 | Info | CREB binding protein (Rubinstein-Taybi syndrome) | H000570_01 | U47741 (external link) | 23598 | CREBBP (external link) | gene_regulation, transcription | 0.0048718 | 1.469 |
| 2399 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H000309_01 | Info | CAMP response element-binding protein CRE-BPa | H000309_01 | L05515 (external link) | 149 | H_GS165L15.1 (external link) | 0.0078273 | 1.479 | |
| 2400 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 (external link) | 75217 | MAP2K4 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 2401 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003332_01 | Info | V-crk avian sarcoma virus CT10 oncogene homolog-like | H003332_01 | X59656 (external link) | 37078 | CRKL (external link) | IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc | 0.0164206 | 0.675 |
| 2402 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H001062_01 | Info | N-acylsphingosine amidohydrolase (acid ceramidase) | H001062_01 | U70063 (external link) | 75811 | ASAH (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … | 0.0187984 | 1.357 |
| 2403 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H000343_01 | Info | Early growth response 3 | H000343_01 | X63741 (external link) | 74088 | EGR3 (external link) | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, cell_signaling | 0.0317099 | 0.777 |
| 2404 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H001348_01 | Info | Phosphoinositide-3-kinase, catalytic, delta polypeptide | H001348_01 | U86453 (external link) | 162808 | PIK3CD (external link) | Inositol phosphate metabolism, Phosphatidylinositol signaling system | 0.0324563 | 1.426 |
| 2405 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003628_01 | Info | Dystroglycan 1 (dystrophin-associated glycoprotein 1) | H003628_01 | L19711 (external link) | 76111 | DAG1 (external link) | Agrin in Postsynaptic Differentiation, immunology | 0.034627 | 0.774 |
| 2406 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H000612_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 3 | H000612_01 | U08316 (external link) | 173965 | RPS6KA3 (external link) | MAP Kinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system | 0.0473043 | 0.79 |
| 2407 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 (external link) | 861 | MAPK3 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 2408 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 (external link) | 190913 | MAPK8 (external link) | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 2409 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H000372_01 | Info | Early growth response 2 (Krox-20 (Drosophila) homolog) | H000372_01 | NM_000399 (external link) | 1395 | EGR2 (external link) | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, immunology | 0.1772326 | 0.796 |
| 2410 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H002943_01 | Info | V-raf murine sarcoma viral oncogene homolog B1 | H002943_01 | M95712 (external link) | 622 | BRAF (external link) | MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc | 0.2376595 | 0.895 |
| 2411 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003309_01 | Info | Mitogen-activated protein kinase kinase 7 | H003309_01 | AF013589 (external link) | 110299 | MAP2K7 (external link) | Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway | 0.3044184 | 1.088 |
| 2412 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H012904_01 | Info | Mitogen-activated protein kinase 8 interacting protein 3 | H012904_01 | AB028989 (external link) | 88500 | MAPK8IP3 (external link) | 0.3112914 | 1.095 | |
| 2413 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H011336_01 | Info | Guanine nucleotide binding protein (G protein), q polypeptide | H011336_01 | U43083 (external link) | 296261 | GNAQ (external link) | Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology | 0.3713616 | 0.89 |
| 2414 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H002673_01 | Info | Tyrosine hydroxylase | H002673_01 | M17589 (external link) | 178237 | TH (external link) | Tyrosine metabolism, behavior, immunology | 0.4825761 | 1.084 |
| 2415 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H011767_01 | Info | SH2-B homolog | H011767_01 | AB037720 (external link) | 15744 | DKFZP547G1110 (external link) | 0.5793807 | 1.053 | |
| 2416 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H014634_01 | Info | Homo sapiens mRNA for FLJ00027 protein, partial CDS | H014634_01 | AK024437 (external link) | 199417 | 0.6135149 | 1.048 | ||
| 2417 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H007842_01 | Info | Gastrin | H007842_01 | NM_000805 (external link) | 2681 | GAS (external link) | immunology | 0.6295543 | 1.041 |
| 2418 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 (external link) | 71816 | AKT1 (external link) | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 2419 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H003163_01 | Info | CAMP responsive element binding protein 1 | H003163_01 | M27691 (external link) | 79194 | CREB1 (external link) | Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology | 0.9300928 | 1.009 |
| 2420 | ST_Differentiation_Pathway_in_PC12_Cells_h | Signalling Transduction KE | H014820_01 | Info | Mitogen-activated protein kinase 9 | H014820_01 | NM_002752 (external link) | 246857 | MAPK9 (external link) | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.9883614 | 0.998 |
| 2421 | integrinPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 (external link) | 296381 | GRB2 (external link) | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 2422 | integrinPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 (external link) | 85181 | RAF1 (external link) | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 2423 | integrinPathway_h | BioCarta | H003332_01 | Info | V-crk avian sarcoma virus CT10 oncogene homolog-like | H003332_01 | X59656 (external link) | 37078 | CRKL (external link) | IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc | 0.0164206 | 0.675 |
| 2424 | integrinPathway_h | BioCarta | H002780_01 | Info | Actinin, alpha 1 | H002780_01 | M95178 (external link) | 119000 | ACTN1 (external link) | 0.0181707 | 0.767 | |
| 2425 | integrinPathway_h | BioCarta | H000692_01 | Info | Actinin, alpha 2 | H000692_01 | M86406 (external link) | 83672 | ACTN2 (external link) | Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, uCalpain and friends in Cell spread, immunology | 0.0617977 | 0.816 |
| 2426 | integrinPathway_h | BioCarta | H005666_01 | Info | KIAA1027 protein | H005666_01 | AB028950 (external link) | 18420 | KIAA1027 (external link) | Apoptotic Signaling in Response to DNA Damage, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Rho cell motility signaling pathway, uCalpain and friends in Cell spread | 0.0638611 | 1.201 |
| 2427 | integrinPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 (external link) | 861 | MAPK3 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 2428 | integrinPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 (external link) | 190913 | MAPK8 (external link) | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 2429 | integrinPathway_h | BioCarta | H002803_01 | Info | Vinculin | H002803_01 | NM_014000 (external link) | 75350 | VCL (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, Rho cell motility signaling pathway, cell_signaling, metastasis | 0.1935883 | 0.885 |
| 2430 | integrinPathway_h | BioCarta | H002112_01 | Info | PTK2 protein tyrosine kinase 2 | H002112_01 | L13616 (external link) | 740 | PTK2 (external link) | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction | 0.2346929 | 0.896 |
| 2431 | integrinPathway_h | BioCarta | H003441_01 | Info | Breakpoint cluster region | H003441_01 | X02596 (external link) | 234799 | BCR (external link) | Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc | 0.2521813 | 1.116 |
| 2432 | integrinPathway_h | BioCarta | H002770_01 | Info | Calpain 4, small subunit (30K) | H002770_01 | X04106 (external link) | 74451 | CAPN4 (external link) | 0.2565365 | 1.091 | |
| 2433 | integrinPathway_h | BioCarta | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 (external link) | 72241 | MAP2K2 (external link) | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 2434 | integrinPathway_h | BioCarta | H008350_01 | Info | Myosin phosphatase, target subunit 2 | H008350_01 | AB007972 (external link) | 130760 | MYPT2 (external link) | CCR3 signaling in Eosinophils, Integrin Signaling Pathway, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Rac 1 cell motility signaling pathway, Rho cell motility signaling pathway, Thrombin signaling and protease-activated receptors | 0.3448422 | 0.932 |
| 2435 | integrinPathway_h | BioCarta | H002440_01 | Info | Homo sapiens clone 24651 mRNA sequence | H002440_01 | AF070648 (external link) | 74034 | Actions of Nitric Oxide in the Heart, Integrin Signaling Pathway | 0.3482926 | 0.855 | |
| 2436 | integrinPathway_h | BioCarta | H002788_01 | Info | Calpain 1, (mu/I) large subunit | H002788_01 | X04366 (external link) | 2575 | CAPN1 (external link) | Deregulation of CDK5 in Alzheimer’s Disease, Integrin Signaling Pathway, mCalpain and friends in Cell motility, uCalpain and friends in Cell spread | 0.4337603 | 1.066 |
| 2437 | integrinPathway_h | BioCarta | H003533_01 | Info | Paxillin | H003533_01 | U14588 (external link) | 102497 | PXN (external link) | Agrin in Postsynaptic Differentiation, Apoptotic Signaling in Response to DNA Damage, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Signaling of Hepatocyte Growth Factor Receptor, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, immunology | 0.4629128 | 1.067 |
| 2438 | integrinPathway_h | BioCarta | H007056_01 | Info | Homo sapiens cDNA FLJ10164 fis, clone HEMBA1003581, moderately similar to TALIN | H007056_01 | AK001026 (external link) | 274265 | Apoptotic Signaling in Response to DNA Damage, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Rho cell motility signaling pathway, uCalpain and friends in Cell spread | 0.5564621 | 1.06 | |
| 2439 | integrinPathway_h | BioCarta | H016089_01 | Info | Caveolin 1, caveolae protein, 22kD | H016089_01 | NM_001753 (external link) | 323469 | CAV1 (external link) | Actions of Nitric Oxide in the Heart, Integrin Signaling Pathway | 0.660791 | 0.934 |
| 2440 | integrinPathway_h | BioCarta | H002212_01 | Info | Zyxin | H002212_01 | X95735 (external link) | 75873 | ZYX (external link) | Integrin Signaling Pathway | 0.7015822 | 1.041 |
| 2441 | integrinPathway_h | BioCarta | H006797_01 | Info | Talin | H006797_01 | AF078828 (external link) | 278559 | TLN (external link) | Apoptotic Signaling in Response to DNA Damage, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Rho cell motility signaling pathway, uCalpain and friends in Cell spread | 0.7205163 | 1.04 |
| 2442 | integrinPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 (external link) | 3446 | MAP2K1 (external link) | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 2443 | integrinPathway_h | BioCarta | H003724_01 | Info | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | H003724_01 | NM_002211 (external link) | 202661 | ITGB1 (external link) | Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis | 0.9378203 | 0.993 |
| 2444 | integrinPathway_h | BioCarta | H003340_01 | Info | C-src tyrosine kinase | H003340_01 | X60114 (external link) | 77793 | CSK (external link) | Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Activation of Src by Protein-tyrosine phosphatase alpha, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, signal_transduction | 0.9390319 | 1.008 |
| 2445 | longevityPathway_h | BioCarta | H000328_01 | Info | Forkhead box O3A | H000328_01 | AF032886 (external link) | 14845 | FOXO3A (external link) | AKT Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, The IGF-1 Receptor and Longevity | 0.0286928 | 0.767 |
| 2446 | longevityPathway_h | BioCarta | H002473_01 | Info | Insulin-like growth factor 1 receptor | H002473_01 | NM_000875 (external link) | 239176 | IGF1R (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology | 0.079692 | 1.158 |
| 2447 | longevityPathway_h | BioCarta | H016047_01 | Info | Superoxide dismutase 2, mitochondrial | H016047_01 | NM_000636 (external link) | 318885 | SOD2 (external link) | Erythropoietin mediated neuroprotection through NF-kB, immunology, pharmacology | 0.0970832 | 1.313 |
| 2448 | longevityPathway_h | BioCarta | H003810_01 | Info | Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | H003810_01 | X02317 (external link) | 75428 | SOD1 (external link) | Cardiac Protection Against ROS , Free Radical Induced Apoptosis, immunology, pharmacology | 0.1871555 | 1.13 |
| 2449 | longevityPathway_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 (external link) | 71816 | AKT1 (external link) | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 2450 | p53_signaling_h | BioCarta | H001935_01 | Info | Glyceraldehyde-3-phosphate dehydrogenase | H001935_01 | U34995 (external link) | 169476 | GAPD (external link) | 0.0001082 | 1.485 | |
| 2451 | p53_signaling_h | BioCarta | H002420_01 | Info | Promyelocytic leukemia | H002420_01 | M79462 (external link) | 89633 | PML (external link) | Regulation of transcriptional activity by PML, gene_regulation, immunology, transcription | 0.0004143 | 0.71 |
| 2452 | p53_signaling_h | BioCarta | H003112_01 | Info | Retinoblastoma 1 (including osteosarcoma) | H003112_01 | L41870 (external link) | 75770 | RB1 (external link) | BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0008596 | 0.674 |
| 2453 | p53_signaling_h | BioCarta | H000570_01 | Info | CREB binding protein (Rubinstein-Taybi syndrome) | H000570_01 | U47741 (external link) | 23598 | CREBBP (external link) | gene_regulation, transcription | 0.0048718 | 1.469 |
| 2454 | p53_signaling_h | BioCarta | H000208_01 | Info | Breast cancer 1, early onset | H000208_01 | NM_007295 (external link) | 194143 | BRCA1 (external link) | ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc | 0.009032 | 0.746 |
| 2455 | p53_signaling_h | BioCarta | H002092_01 | Info | Ataxia telangiectasia and Rad3 related | H002092_01 | U49844 (external link) | 77613 | ATR (external link) | Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology | 0.0105491 | 0.753 |
| 2456 | p53_signaling_h | BioCarta | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 (external link) | 75217 | MAP2K4 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 2457 | p53_signaling_h | BioCarta | H009536_01 | Info | Homo sapiens mRNA for P53TG1-D, complete CDS | H009536_01 | AB007458 (external link) | 306301 | 0.0126191 | 0.748 | ||
| 2458 | p53_signaling_h | BioCarta | H003739_01 | Info | Cell division cycle 2, G1 to S and G2 to M | H003739_01 | X05360 (external link) | 184572 | CDC2 (external link) | Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle | 0.0222229 | 0.733 |
| 2459 | p53_signaling_h | BioCarta | H002519_01 | Info | Heat shock 70kD protein 4 | H002519_01 | AB023420 (external link) | 90093 | HSPA4 (external link) | Chaperones modulate interferon Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) | 0.0234203 | 0.803 |
| 2460 | p53_signaling_h | BioCarta | H003410_01 | Info | Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | H003410_01 | U26727 (external link) | 1174 | CDKN2A (external link) | Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0245577 | 0.782 |
| 2461 | p53_signaling_h | BioCarta | H002789_01 | Info | Tumor protein p53 (Li-Fraumeni syndrome) | H002789_01 | NM_000546 (external link) | 1846 | TP53 (external link) | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc | 0.0273242 | 1.207 |
| 2462 | p53_signaling_h | BioCarta | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 (external link) | 77202 | PRKCB1 (external link) | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 2463 | p53_signaling_h | BioCarta | H002149_01 | Info | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | H002149_01 | U03106 (external link) | 179665 | CDKN1A (external link) | ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc | 0.0349766 | 1.236 |
| 2464 | p53_signaling_h | BioCarta | H002194_01 | Info | Casein kinase 1, alpha 1 | H002194_01 | L37042 (external link) | 283738 | CSNK1A1 (external link) | Deregulation of CDK5 in Alzheimer’s Disease, Hypoxia and p53 in the Cardiovascular system, NFAT and Hypertrophy of the heart (Transcription in the broken heart), WNT Signaling Pathway, cell_cycle, cell_signaling, signal_transduction | 0.0461818 | 0.809 |
| 2465 | p53_signaling_h | BioCarta | H003180_01 | Info | TATA box binding protein | H003180_01 | M55654 (external link) | 1100 | TBP (external link) | CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Hypoxia and p53 in the Cardiovascular system, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, RNA polymerase III transcription, immunology | 0.0482733 | 0.827 |
| 2466 | p53_signaling_h | BioCarta | H003259_01 | Info | Sp1 transcription factor | H003259_01 | J03133 (external link) | 2021 | SP1 (external link) | Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation | 0.0557417 | 0.814 |
| 2467 | p53_signaling_h | BioCarta | H000291_01 | Info | TNF receptor-associated factor 4 | H000291_01 | X80200 (external link) | 8375 | TRAF4 (external link) | immunology | 0.0787384 | 0.81 |
| 2468 | p53_signaling_h | BioCarta | H002049_01 | Info | Death-associated protein 6 | H002049_01 | AB015051 (external link) | 180224 | DAXX (external link) | FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis | 0.0788021 | 1.159 |
| 2469 | p53_signaling_h | BioCarta | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 (external link) | 758 | RASA1 (external link) | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 2470 | p53_signaling_h | BioCarta | H014546_01 | Info | Peptidylprolyl isomerase A (cyclophilin A) | H014546_01 | NM_021130 (external link) | 182937 | PPIA (external link) | IL-2 Receptor Beta Chain in T cell Activation | 0.129858 | 1.176 |
| 2471 | p53_signaling_h | BioCarta | H014140_01 | Info | Leucine rich repeat and death domain containing protein | H014140_01 | NM_018494 (external link) | 123136 | LRDD (external link) | 0.1769387 | 0.848 | |
| 2472 | p53_signaling_h | BioCarta | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 (external link) | 79070 | MYC (external link) | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 2473 | p53_signaling_h | BioCarta | H008177_01 | Info | N-myc downstream-regulated gene 2 | H008177_01 | AB033074 (external link) | 243960 | NDRG2 (external link) | 0.2117752 | 0.899 | |
| 2474 | p53_signaling_h | BioCarta | H007835_01 | Info | Sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 1 | H007835_01 | NM_012238 (external link) | 31176 | SIRT1 (external link) | Regulation of transcriptional activity by PML | 0.2402857 | 0.874 |
| 2475 | p53_signaling_h | BioCarta | H003264_01 | Info | Caspase 9, apoptosis-related cysteine protease | H003264_01 | U60521 (external link) | 100641 | CASP9 (external link) | AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Ras Signaling Pathway, Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, Trefoil Factors Initiate Mucosal Healing, West Nile Virus, apoptosis, immunology | 0.2463073 | 0.872 |
| 2476 | p53_signaling_h | BioCarta | H003605_01 | Info | BCL2-associated X protein | H003605_01 | L22474 (external link) | 159428 | BAX (external link) | Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology | 0.253339 | 0.907 |
| 2477 | p53_signaling_h | BioCarta | H006662_01 | Info | Fas (TNFRSF6)-associated via death domain | H006662_01 | X84709 (external link) | 86131 | FADD (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , NF-kB Signaling Pathway, SODD/TNFR1 Signaling Pathway, TNFR1 Signaling Pathway, immunology | 0.292449 | 1.108 |
| 2478 | p53_signaling_h | BioCarta | H003309_01 | Info | Mitogen-activated protein kinase kinase 7 | H003309_01 | AF013589 (external link) | 110299 | MAP2K7 (external link) | Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway | 0.3044184 | 1.088 |
| 2479 | p53_signaling_h | BioCarta | H002771_01 | Info | APEX nuclease (multifunctional DNA repair enzyme) | H002771_01 | S43127 (external link) | 73722 | APEX (external link) | Granzyme A mediated Apoptosis Pathway | 0.3286377 | 0.907 |
| 2480 | p53_signaling_h | BioCarta | H007300_01 | Info | P53-inducible ribonucleotide reductase small subunit 2 homolog | H007300_01 | AB036063 (external link) | 94262 | p53R2 (external link) | 0.359173 | 1.087 | |
| 2481 | p53_signaling_h | BioCarta | H003351_01 | Info | Protein kinase, DNA-activated, catalytic polypeptide | H003351_01 | U47077 (external link) | 155637 | PRKDC (external link) | Cell Cycle: G2/M Checkpoint, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system, DNA_damage, immunology | 0.3847336 | 0.919 |
| 2482 | p53_signaling_h | BioCarta | H015371_01 | Info | MDM2 (mouse double minute 2)-binding protein, 104kD | H015371_01 | NM_022045 (external link) | 287481 | MTBP (external link) | 0.414917 | 1.078 | |
| 2483 | p53_signaling_h | BioCarta | H000454_01 | Info | Tumor necrosis factor, alpha-induced protein 1 (endothelial) | H000454_01 | M80783 (external link) | 76090 | TNFAIP1 (external link) | apoptosis, cell_cycle, cell_signaling, signal_transduction | 0.4282517 | 0.923 |
| 2484 | p53_signaling_h | BioCarta | H014854_01 | Info | Hypothetical protein FLJ12296 similar to wild-type p53-induced gene 1 | H014854_01 | NM_022470 (external link) | 252406 | FLJ12296 (external link) | 0.5316076 | 1.055 | |
| 2485 | p53_signaling_h | BioCarta | H005981_01 | Info | Homo sapiens clone 24670 mRNA sequence | H005981_01 | AF055019 (external link) | 13417 | 0.5614285 | 1.063 | ||
| 2486 | p53_signaling_h | BioCarta | H001952_01 | Info | Ribosomal protein L13a | H001952_01 | X56932 (external link) | 119122 | RPL13A (external link) | 0.565051 | 1.059 | |
| 2487 | p53_signaling_h | BioCarta | H004814_01 | Info | N-myc downstream regulated | H004814_01 | D87953 (external link) | 75789 | NDRG1 (external link) | 0.5742952 | 1.047 | |
| 2488 | p53_signaling_h | BioCarta | H000059_01 | Info | Etoposide-induced mRNA | H000059_01 | AF010313 (external link) | 286027 | PIG8 (external link) | 0.5894467 | 0.95 | |
| 2489 | p53_signaling_h | BioCarta | H005625_01 | Info | Homo sapiens mRNA; cDNA DKFZp586C1817 (from clone DKFZp586C1817) | H005625_01 | AL133574 (external link) | 42458 | 0.60529 | 0.958 | ||
| 2490 | p53_signaling_h | BioCarta | H003538_01 | Info | Actin, beta | H003538_01 | NM_001101 (external link) | 288061 | ACTB (external link) | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes | 0.6253266 | 0.956 |
| 2491 | p53_signaling_h | BioCarta | H003045_01 | Info | Tumor necrosis factor receptor superfamily, member 10b | H003045_01 | AF016266 (external link) | 51233 | TNFRSF10B (external link) | 0.6371361 | 1.047 | |
| 2492 | p53_signaling_h | BioCarta | H010339_01 | Info | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) | H010339_01 | AF045581 (external link) | 106674 | BAP1 (external link) | 0.6920721 | 0.961 | |
| 2493 | p53_signaling_h | BioCarta | H006401_01 | Info | Fas (TNFRSF6) associated factor 1 | H006401_01 | AJ271408 (external link) | 25821 | FAF1 (external link) | FAS signaling pathway ( CD95 ) | 0.773612 | 1.035 |
| 2494 | p53_signaling_h | BioCarta | H000475_01 | Info | Apoptotic protease activating factor | H000475_01 | NM_013229 (external link) | 77579 | APAF1 (external link) | Apoptotic Signaling in Response to DNA Damage, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , p53 Signaling Pathway, Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, Trefoil Factors Initiate Mucosal Healing, apoptosis, immunology | 0.7764943 | 0.97 |
| 2495 | p53_signaling_h | BioCarta | H006841_01 | Info | Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) | H006841_01 | AL049301 (external link) | 278577 | Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology | 0.7810094 | 0.98 | |
| 2496 | p53_signaling_h | BioCarta | H003558_01 | Info | Tumor protein p53-binding protein, 2 | H003558_01 | U58334 (external link) | 44585 | TP53BP2 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, apoptosis, tsonc | 0.7880942 | 0.97 |
| 2497 | p53_signaling_h | BioCarta | H004162_01 | Info | Mesenchymal stem cell protein DSCD28 | H004162_01 | AF242772 (external link) | 272416 | LOC51336 (external link) | FAS signaling pathway ( CD95 ) | 0.7944947 | 0.98 |
| 2498 | p53_signaling_h | BioCarta | H003766_01 | Info | Mouse double minute 2, human homolog of; p53-binding protein | H003766_01 | M92424 (external link) | 170027 | MDM2 (external link) | ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc | 0.8018001 | 0.978 |
| 2499 | p53_signaling_h | BioCarta | H001681_01 | Info | Protein kinase C, theta | H001681_01 | L01087 (external link) | 211593 | PRKCQ (external link) | Keratinocyte Differentiation, cell_cycle, cell_signaling, immunology, signal_transduction | 0.8037373 | 1.019 |
| 2500 | p53_signaling_h | BioCarta | H009125_01 | Info | Bcl-2 binding component 3 | H009125_01 | U82987 (external link) | 87246 | BBC3 (external link) | 0.8477416 | 0.982 | |
| 2501 | p53_signaling_h | BioCarta | H001596_01 | Info | Protein kinase C, gamma | H001596_01 | Z15114 (external link) | 2890 | PRKCG (external link) | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.8498034 | 1.018 |
| 2502 | p53_signaling_h | BioCarta | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 (external link) | 83428 | NFKB1 (external link) | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 2503 | p53_signaling_h | BioCarta | H007630_01 | Info | TP53 target gene 1 | H007630_01 | AB007455 (external link) | 274329 | TP53TG1 (external link) | 0.894961 | 1.012 | |
| 2504 | p53_signaling_h | BioCarta | H002606_01 | Info | Cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) | H002606_01 | L20320 (external link) | 184298 | CDK7 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Cyclins and Cell Cycle Regulation, Degradation of the RAR and RXR by the proteasome, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.9364784 | 0.991 |
| 2505 | p53_signaling_h | BioCarta | H003151_01 | Info | E1A binding protein p300 | H003151_01 | U01877 (external link) | 25272 | EP300 (external link) | Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription | 0.9607239 | 1.004 |
| 2506 | p53_signaling_h | BioCarta | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 (external link) | 75569 | RELA (external link) | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 2507 | p53_signaling_h | BioCarta | H002746_01 | Info | TNF receptor-associated factor 5 | H002746_01 | AB000509 (external link) | 29736 | TRAF5 (external link) | TACI and BCMA stimulation of B cell immune responses., immunology | 0.9871372 | 0.999 |
| 2508 | ST_ADRENERGIC_h | Signalling Transduction KE | H002040_01 | Info | Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) | H002040_01 | X00588 (external link) | 77432 | EGFR (external link) | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc | 0.0004362 | 0.669 |
| 2509 | ST_ADRENERGIC_h | Signalling Transduction KE | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 (external link) | 85181 | RAF1 (external link) | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 2510 | ST_ADRENERGIC_h | Signalling Transduction KE | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 (external link) | 79107 | MAPK14 (external link) | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 2511 | ST_ADRENERGIC_h | Signalling Transduction KE | H001062_01 | Info | N-acylsphingosine amidohydrolase (acid ceramidase) | H001062_01 | U70063 (external link) | 75811 | ASAH (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … | 0.0187984 | 1.357 |
| 2512 | ST_ADRENERGIC_h | Signalling Transduction KE | H006644_01 | Info | Phosphorylase kinase, alpha 2 (liver) | H006644_01 | X80497 (external link) | 54941 | PHKA2 (external link) | cell_cycle, cell_signaling, signal_transduction | 0.0321533 | 1.233 |
| 2513 | ST_ADRENERGIC_h | Signalling Transduction KE | H001348_01 | Info | Phosphoinositide-3-kinase, catalytic, delta polypeptide | H001348_01 | U86453 (external link) | 162808 | PIK3CD (external link) | Inositol phosphate metabolism, Phosphatidylinositol signaling system | 0.0324563 | 1.426 |
| 2514 | ST_ADRENERGIC_h | Signalling Transduction KE | H003628_01 | Info | Dystroglycan 1 (dystrophin-associated glycoprotein 1) | H003628_01 | L19711 (external link) | 76111 | DAG1 (external link) | Agrin in Postsynaptic Differentiation, immunology | 0.034627 | 0.774 |
| 2515 | ST_ADRENERGIC_h | Signalling Transduction KE | H001748_01 | Info | Inositol 1,4,5-trisphosphate 3-kinase B | H001748_01 | X57206 (external link) | 78877 | ITPKB (external link) | Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction | 0.1283627 | 0.851 |
| 2516 | ST_ADRENERGIC_h | Signalling Transduction KE | H001718_01 | Info | Inositol 1,4,5-trisphosphate 3-kinase A | H001718_01 | X54938 (external link) | 2722 | ITPKA (external link) | Inositol phosphate metabolism, Phosphatidylinositol signaling system | 0.1331494 | 1.16 |
| 2517 | ST_ADRENERGIC_h | Signalling Transduction KE | H002943_01 | Info | V-raf murine sarcoma viral oncogene homolog B1 | H002943_01 | M95712 (external link) | 622 | BRAF (external link) | MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc | 0.2376595 | 0.895 |
| 2518 | ST_ADRENERGIC_h | Signalling Transduction KE | H000614_01 | Info | Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | H000614_01 | M69013 (external link) | 1686 | GNA11 (external link) | 0.3060018 | 0.9 | |
| 2519 | ST_ADRENERGIC_h | Signalling Transduction KE | H003337_01 | Info | B-factor, properdin | H003337_01 | L15702 (external link) | 69771 | BF (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, immunology | 0.3702495 | 1.093 |
| 2520 | ST_ADRENERGIC_h | Signalling Transduction KE | H011336_01 | Info | Guanine nucleotide binding protein (G protein), q polypeptide | H011336_01 | U43083 (external link) | 296261 | GNAQ (external link) | Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology | 0.3713616 | 0.89 |
| 2521 | ST_ADRENERGIC_h | Signalling Transduction KE | H010976_01 | Info | Guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | H010976_01 | M63904 (external link) | 73797 | GNA15 (external link) | 0.4609468 | 0.929 | |
| 2522 | ST_ADRENERGIC_h | Signalling Transduction KE | H000897_01 | Info | Inositol 1,4,5-triphosphate receptor, type 2 | H000897_01 | D26350 (external link) | 238272 | ITPR2 (external link) | 0.5011337 | 1.061 | |
| 2523 | ST_ADRENERGIC_h | Signalling Transduction KE | H001215_01 | Info | Pentaxin-related gene, rapidly induced by IL-1 beta | H001215_01 | M31166 (external link) | 2050 | PTX3 (external link) | cell_cycle, cell_signaling, immunology | 0.5618599 | 0.929 |
| 2524 | ST_ADRENERGIC_h | Signalling Transduction KE | H006635_01 | Info | Homo sapiens clone 23607 mRNA sequence | H006635_01 | AF038181 (external link) | 167825 | ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc | 0.6181322 | 1.041 | |
| 2525 | ST_ADRENERGIC_h | Signalling Transduction KE | H007842_01 | Info | Gastrin | H007842_01 | NM_000805 (external link) | 2681 | GAS (external link) | immunology | 0.6295543 | 1.041 |
| 2526 | ST_ADRENERGIC_h | Signalling Transduction KE | H011599_01 | Info | Homo sapiens mRNA; cDNA DKFZp434J194 (from clone DKFZp434J194) | H011599_01 | AL110227 (external link) | 323067 | 0.661501 | 0.954 | ||
| 2527 | ST_ADRENERGIC_h | Signalling Transduction KE | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 (external link) | 71816 | AKT1 (external link) | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 2528 | ST_ADRENERGIC_h | Signalling Transduction KE | H000460_01 | Info | Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | H000460_01 | AL049933 (external link) | 203862 | GNAI1 (external link) | Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Bioactive Peptide Induced Signaling Pathway, CXCR4 Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Phospholipids as signaling intermediaries, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, cell_signaling, signal_transduction | 0.7235673 | 1.046 |
| 2529 | ST_ADRENERGIC_h | Signalling Transduction KE | H008143_01 | Info | CDA14 | H008143_01 | AF216751 (external link) | 26813 | LOC51290 (external link) | 0.758068 | 1.029 | |
| 2530 | ST_ADRENERGIC_h | Signalling Transduction KE | H007337_01 | Info | Inositol 1,4,5-triphosphate receptor, type 3 | H007337_01 | U01062 (external link) | 77515 | ITPR3 (external link) | 0.8999809 | 0.984 | |
| 2531 | ST_ADRENERGIC_h | Signalling Transduction KE | H003791_01 | Info | Small inducible cytokine subfamily A (Cys-Cys), member 13 | H003791_01 | U59808 (external link) | 11383 | SCYA13 (external link) | 0.9937199 | 1.001 | |
| 2532 | ptenPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 (external link) | 296381 | GRB2 (external link) | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 2533 | ptenPathway_h | BioCarta | H000328_01 | Info | Forkhead box O3A | H000328_01 | AF032886 (external link) | 14845 | FOXO3A (external link) | AKT Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, The IGF-1 Receptor and Longevity | 0.0286928 | 0.767 |
| 2534 | ptenPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 (external link) | 861 | MAPK3 (external link) | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 2535 | ptenPathway_h | BioCarta | H002970_01 | Info | Integrin-linked kinase | H002970_01 | U40282 (external link) | 6196 | ILK (external link) | PTEN dependent cell cycle arrest and apoptosis, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.1701136 | 1.128 |
| 2536 | ptenPathway_h | BioCarta | H002112_01 | Info | PTK2 protein tyrosine kinase 2 | H002112_01 | L13616 (external link) | 740 | PTK2 (external link) | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction | 0.2346929 | 0.896 |
| 2537 | ptenPathway_h | BioCarta | H003286_01 | Info | 3-phosphoinositide dependent protein kinase-1 | H003286_01 | AF017995 (external link) | 154729 | PDPK1 (external link) | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.2543058 | 1.119 |
| 2538 | ptenPathway_h | BioCarta | H013300_01 | Info | Pyruvate dehydrogenase kinase, isoenzyme 2 | H013300_01 | L42451 (external link) | 92261 | PDK2 (external link) | mTOR Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, cell_cycle, cell_signaling, signal_transduction | 0.5991595 | 0.949 |
| 2539 | ptenPathway_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 (external link) | 71816 | AKT1 (external link) | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 2540 | ptenPathway_h | BioCarta | H003724_01 | Info | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | H003724_01 | NM_002211 (external link) | 202661 | ITGB1 (external link) | Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis | 0.9378203 | 0.993 |
Date and time of the analysis:
Name of the project file: SSc PBC.xls
Time of the analysis: Sun May 06 14:48:57 2007
BRB-ArrayTools Version: 3.6.0 – Beta_1 (May 2007)
Spot Filters:
Exclude the spot if the Spot Flag contains any of the following values: 0
Normalization:
Normalize (center) each array using lowess smoother.
Exclude a gene under any of the following conditions:
Percent of data missing or filtered out exceeds 25 %
Gene Subsets: OFF