Pathway Comparison – Page Three

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Order Broad Pathway Pathway description Unique id Annotations Description Clone GB acc UG cluster Gene symbol Defined gene lists Parametric p-value Geometric mean of ratios (class Disease /class Normal )
1162 ST_G_alpha_i_Pathway__h Signalling Transduction KE H001717_01 Info RAP1, GTPase activating protein 1 H001717_01 M64788 (external link) 75151 RAP1GA1 (external link) 0.0888214 1.197
1163 ST_G_alpha_i_Pathway__h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 (external link) 78877 ITPKB (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
1164 ST_G_alpha_i_Pathway__h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 (external link) 2722 ITPKA (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
1165 ST_G_alpha_i_Pathway__h Signalling Transduction KE H002097_01 Info Dopamine receptor D2 H002097_01 X51362 (external link) 73893 DRD2 (external link) behavior, immunology 0.1531006 0.865
1166 ST_G_alpha_i_Pathway__h Signalling Transduction KE H002346_01 Info Phospholipase C, beta 2 H002346_01 M95678 (external link) 994 PLCB2 (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.158235 1.161
1167 ST_G_alpha_i_Pathway__h Signalling Transduction KE H009013_01 Info Dopamine receptor D2 H009013_01 AF176812 (external link) 73893 DRD2 (external link) behavior, immunology 0.2238033 1.119
1168 ST_G_alpha_i_Pathway__h Signalling Transduction KE H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 (external link) 622 BRAF (external link) MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
1169 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1170 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 (external link) 69771 BF (external link) Perou’s – Intrinsi c- Breast-Cancer-Genes, immunology 0.3702495 1.093
1171 ST_G_alpha_i_Pathway__h Signalling Transduction KE H000897_01 Info Inositol 1,4,5-triphosphate receptor, type 2 H000897_01 D26350 (external link) 238272 ITPR2 (external link) 0.5011337 1.061
1172 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1173 ST_G_alpha_i_Pathway__h Signalling Transduction KE H003651_01 Info EphB2 H003651_01 AF025304 (external link) 125124 EPHB2 (external link) development 0.7855294 0.971
1174 ST_G_alpha_i_Pathway__h Signalling Transduction KE H007337_01 Info Inositol 1,4,5-triphosphate receptor, type 3 H007337_01 U01062 (external link) 77515 ITPR3 (external link) 0.8999809 0.984
1175 ST_G_alpha_i_Pathway__h Signalling Transduction KE H014981_01 Info Phospholipase C, beta 4 H014981_01 NM_000933 (external link) 283006 PLCB4 (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.9133619 0.989
1176 tpoPathway_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1177 tpoPathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1178 tpoPathway_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1179 tpoPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1180 tpoPathway_h BioCarta H001600_01 Info RAS p21 protein activator (GTPase activating protein) 1 H001600_01 M23379 (external link) 758 RASA1 (external link) EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction 0.1015906 0.844
1181 tpoPathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 (external link) 244613 STAT5B (external link) 0.441402 1.071
1182 tpoPathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 (external link) 24064 0.509279 1.056
1183 tpoPathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1184 gleevecPathway_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1185 gleevecPathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1186 gleevecPathway_h BioCarta H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1187 gleevecPathway_h BioCarta H003332_01 Info V-crk avian sarcoma virus CT10 oncogene homolog-like H003332_01 X59656 (external link) 37078 CRKL (external link) IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc 0.0164206 0.675
1188 gleevecPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1189 gleevecPathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1190 gleevecPathway_h BioCarta H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 (external link) 79070 MYC (external link) Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
1191 gleevecPathway_h BioCarta H003441_01 Info Breakpoint cluster region H003441_01 X02596 (external link) 234799 BCR (external link) Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc 0.2521813 1.116
1192 gleevecPathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 (external link) 244613 STAT5B (external link) 0.441402 1.071
1193 gleevecPathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 (external link) 24064 0.509279 1.056
1194 gleevecPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1195 gleevecPathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1196 il2Pathway_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1197 il2Pathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1198 il2Pathway_h BioCarta H003718_01 Info Interleukin 2 receptor, gamma (severe combined immunodeficiency) H003718_01 D11086 (external link) 84 IL2RG (external link) IL 2 signaling pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, immunology 0.0314631 1.258
1199 il2Pathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1200 il2Pathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1201 il2Pathway_h BioCarta H003820_01 Info Lymphocyte-specific protein tyrosine kinase H003820_01 X05027 (external link) 1765 LCK (external link) Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc 0.2266863 0.873
1202 il2Pathway_h BioCarta H001349_01 Info Janus kinase 1 (a protein tyrosine kinase) H001349_01 M64174 (external link) 50651 JAK1 (external link) EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction 0.2754104 1.129
1203 il2Pathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 (external link) 244613 STAT5B (external link) 0.441402 1.071
1204 il2Pathway_h BioCarta H002824_01 Info Janus kinase 3 (a protein tyrosine kinase, leukocyte) H002824_01 U09607 (external link) 99877 JAK3 (external link) IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction 0.4735774 1.051
1205 il2Pathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 (external link) 24064 0.509279 1.056
1206 il2Pathway_h BioCarta H003650_01 Info Interleukin 2 receptor, alpha H003650_01 X01057 (external link) 1724 IL2RA (external link) IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology 0.5932248 1.054
1207 il2Pathway_h BioCarta H002570_01 Info Interleukin 2 H002570_01 S82692 (external link) 89679 IL2 (external link) Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology 0.6483346 1.043
1208 il2Pathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1209 pparaPathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
1210 pparaPathway_h BioCarta H002547_01 Info Lipoprotein lipase H002547_01 M15856 (external link) 180878 LPL (external link) Low-density lipoprotein (LDL) pathway during atherogenesis, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome, Glycerolipid metabolism, immunology 0.0011159 0.719
1211 pparaPathway_h BioCarta H000570_01 Info CREB binding protein (Rubinstein-Taybi syndrome) H000570_01 U47741 (external link) 23598 CREBBP (external link) gene_regulation, transcription 0.0048718 1.469
1212 pparaPathway_h BioCarta H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 (external link) 87773 PRKACB (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1213 pparaPathway_h BioCarta H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 (external link) 20084 RXRA (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
1214 pparaPathway_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1215 pparaPathway_h BioCarta H001374_01 Info PPAR binding protein H001374_01 Y13467 (external link) 15589 PPARBP (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, CARM1 and Regulation of the Estrogen Receptor, Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Multi-step Regulation of Transcription by Pitx2, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis 0.0333785 0.803
1216 pparaPathway_h BioCarta H002187_01 Info Nuclear receptor subfamily 2, group F, member 1 H002187_01 X16155 (external link) 144630 NR2F1 (external link) Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.0403086 0.792
1217 pparaPathway_h BioCarta H003259_01 Info Sp1 transcription factor H003259_01 J03133 (external link) 2021 SP1 (external link) Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.0557417 0.814
1218 pparaPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1219 pparaPathway_h BioCarta H008186_01 Info Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 H008186_01 AF109161 (external link) 82071 CITED2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.1031104 0.841
1220 pparaPathway_h BioCarta H003198_01 Info Fatty acid binding protein 1, liver H003198_01 M10050 (external link) 5241 FABP1 (external link) Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), immunology 0.1414926 0.883
1221 pparaPathway_h BioCarta H002871_01 Info Apolipoprotein A-I H002871_01 X02162 (external link) 93194 APOA1 (external link) Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), immunology 0.1551541 0.794
1222 pparaPathway_h BioCarta H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 (external link) 79070 MYC (external link) Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
1223 pparaPathway_h BioCarta H013590_01 Info Nuclear receptor co-repressor 1 H013590_01 AF044209 (external link) 144904 NCOR1 (external link) Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.2336483 0.899
1224 pparaPathway_h BioCarta H001698_01 Info Protein kinase, cAMP-dependent, regulatory, type II, alpha H001698_01 X14968 (external link) 289075 PRKAR2A (external link) AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation 0.2569617 1.125
1225 pparaPathway_h BioCarta H000174_01 Info Heat shock 90kD protein 1, alpha H000174_01 X15183 (external link) 289088 HSPCA (external link) 0.3292659 0.896
1226 pparaPathway_h BioCarta H002882_01 Info Nuclear receptor co-repressor 2 H002882_01 NM_006312 (external link) 287994 NCOR2 (external link) CARM1 and Regulation of the Estrogen Receptor, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), METS affect on Macrophage Differentiation, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells 0.3492591 0.931
1227 pparaPathway_h BioCarta H007099_01 Info Choline kinase-like H007099_01 AL096780 (external link) 154886 CHKL (external link) Fatty acid metabolism 0.3964303 0.907
1228 pparaPathway_h BioCarta H000645_01 Info Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 (external link) 183037 PRKAR1A (external link) Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction 0.4305614 0.935
1229 pparaPathway_h BioCarta H002261_01 Info Signal transducer and activator of transcription 5B H002261_01 U47686 (external link) 244613 STAT5B (external link) 0.441402 1.071
1230 pparaPathway_h BioCarta H002035_01 Info FAT tumor suppressor (Drosophila) homolog H002035_01 X87241 (external link) 166994 FAT (external link) cell_signaling, immunology, metastasis, tsonc 0.4989072 0.922
1231 pparaPathway_h BioCarta H009068_01 Info Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) H009068_01 AL080218 (external link) 24064 0.509279 1.056
1232 pparaPathway_h BioCarta H000780_01 Info Nuclear receptor subfamily 1, group H, member 3 H000780_01 U22662 (external link) 81336 NR1H3 (external link) FXR and LXR Regulation of Cholesterol Metabolism, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity 0.578592 1.089
1233 pparaPathway_h BioCarta H008686_01 Info DUTP pyrophosphatase H008686_01 U31930 (external link) 82113 DUT (external link) Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Pyrimidine metabolism, gene_regulation, transcription 0.6087897 1.051
1234 pparaPathway_h BioCarta H003231_01 Info Platelet-derived growth factor alpha polypeptide H003231_01 X06374 (external link) 37040 PDGFA (external link) Cytokines and Inflammatory Response, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), PDGF Signaling Pathway, Phospholipids as signaling intermediaries, immunology, misc, signal_transduction 0.6989894 1.039
1235 pparaPathway_h BioCarta H003875_01 Info Hydroxysteroid (17-beta) dehydrogenase 4 H003875_01 X87176 (external link) 75441 HSD17B4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Androgen and estrogen metabolism 0.7514294 0.968
1236 pparaPathway_h BioCarta H003434_01 Info Dual specificity phosphatase 1 H003434_01 NM_004417 (external link) 171695 DUSP1 (external link) CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway 0.8183145 0.968
1237 pparaPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1238 pparaPathway_h BioCarta H002350_01 Info Peroxisome proliferative activated receptor, alpha H002350_01 L02932 (external link) 998 PPARA (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway 0.8655149 1.015
1239 pparaPathway_h BioCarta H015634_01 Info Heat shock 90kD protein 1, alpha H015634_01 NM_005348 (external link) 289088 HSPCA (external link) 0.8774982 1.018
1240 pparaPathway_h BioCarta H003151_01 Info E1A binding protein p300 H003151_01 U01877 (external link) 25272 EP300 (external link) Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
1241 pparaPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1242 pparaPathway_h BioCarta H004913_01 Info CGI-113 protein H004913_01 NM_016050 (external link) 152738 LOC51017 (external link) Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.9894647 0.999
1243 GNF_FEMALE_GENES_h na H006305_01 Info O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylgluco H006305_01 NM_003605 (external link) 100293 OGT (external link) 0.0029258 1.335
1244 GNF_FEMALE_GENES_h na H000959_01 Info Glycophorin C (Gerbich blood group) H000959_01 NM_002101 (external link) 81994 GYPC (external link) 0.0034104 1.545
1245 GNF_FEMALE_GENES_h na H009875_01 Info Lysosomal-associated multispanning membrane protein-5 H009875_01 U51240 (external link) 79356 LAPTM5 (external link) 0.0035021 1.539
1246 GNF_FEMALE_GENES_h na H000665_01 Info Guanylate binding protein 2, interferon-inducible H000665_01 M55543 (external link) 171862 GBP2 (external link) cell_signaling 0.003713 1.543
1247 GNF_FEMALE_GENES_h na H009171_01 Info GRB2-associated binding protein 2 H009171_01 AB011143 (external link) 30687 GAB2 (external link) 0.0046478 1.423
1248 GNF_FEMALE_GENES_h na H012004_01 Info Retinal short-chain dehydrogenase/reductase retSDR2 H012004_01 NM_016245 (external link) 12150 LOC51170 (external link) 0.0066239 1.439
1249 GNF_FEMALE_GENES_h na H002047_01 Info Transforming growth factor, beta receptor III (betaglycan, 300kD) H002047_01 L07594 (external link) 79059 TGFBR3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, ALK in cardiac myocytes, CTCF: First Multivalent Nuclear Factor, Role of Tob in T-cell activation, immunology 0.0081449 0.728
1250 GNF_FEMALE_GENES_h na H001037_01 Info Proteoglycan 1, secretory granule H001037_01 X17042 (external link) 1908 PRG1 (external link) immunology 0.0087226 1.629
1251 GNF_FEMALE_GENES_h na H014142_01 Info Sodium calcium exchanger H014142_01 NM_020689 (external link) 12321 NCKX3 (external link) 0.0169504 1.231
1252 GNF_FEMALE_GENES_h na H006288_01 Info AE-binding protein 1 H006288_01 AF053944 (external link) 118397 AEBP1 (external link) 0.0298793 0.787
1253 GNF_FEMALE_GENES_h na H000044_01 Info Ribosomal protein L31 H000044_01 X15940 (external link) 184014 RPL31 (external link) 0.0622533 0.75
1254 GNF_FEMALE_GENES_h na H003123_01 Info Nicotinamide N-methyltransferase H003123_01 U08021 (external link) 76669 NNMT (external link) Nicotinate and nicotinamide metabolism, immunology 0.070177 0.777
1255 GNF_FEMALE_GENES_h na H000486_01 Info Interferon induced transmembrane protein 2 (1-8D) H000486_01 X57351 (external link) 174195 IFITM2 (external link) 0.0726328 0.803
1256 GNF_FEMALE_GENES_h na H001954_01 Info Milk fat globule-EGF factor 8 protein H001954_01 U58516 (external link) 3745 MFGE8 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.082982 0.826
1257 GNF_FEMALE_GENES_h na H004936_01 Info DKFZP564A122 protein H004936_01 AL110269 (external link) 187991 DKFZP564A122 (external link) 0.0852946 1.175
1258 GNF_FEMALE_GENES_h na H002959_01 Info Small inducible cytokine subfamily A (Cys-Cys), member 21 H002959_01 AB002409 (external link) 57907 SCYA21 (external link) 0.0998916 0.822
1259 GNF_FEMALE_GENES_h na H003735_01 Info Insulin-like growth factor binding protein 5 H003735_01 AF055033 (external link) 107169 IGFBP5 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Ghrelin: Regulation of Food Intake and Energy Homeostasis 0.1007284 0.858
1260 GNF_FEMALE_GENES_h na H012158_01 Info Upregulated by 1,25-dihydroxyvitamin D-3 H012158_01 S73591 (external link) 179526 VDUP1 (external link) 0.1293789 1.193
1261 GNF_FEMALE_GENES_h na H005384_01 Info Homo sapiens mRNA; cDNA DKFZp564H0764 (from clone DKFZp564H0764) H005384_01 AL117617 (external link) 239870 0.1303249 1.15
1262 GNF_FEMALE_GENES_h na H000774_01 Info Collagen, type VI, alpha 1 H000774_01 X15880 (external link) 108885 COL6A1 (external link) 0.1448402 0.841
1263 GNF_FEMALE_GENES_h na H010255_01 Info Ribosomal protein S17 H010255_01 M13932 (external link) 5174 RPS17 (external link) 0.1480605 1.185
1264 GNF_FEMALE_GENES_h na H002105_01 Info Ribosomal protein S3 H002105_01 X55715 (external link) 252259 RPS3 (external link) 0.1493113 1.139
1265 GNF_FEMALE_GENES_h na H000239_01 Info Microphthalmia-associated transcription factor H000239_01 AB006909 (external link) 166017 MITF (external link) Melanocyte Development and Pigmentation Pathway, immunology 0.1500822 0.862
1266 GNF_FEMALE_GENES_h na H001266_01 Info RNA binding motif, single stranded interacting protein 1 H001266_01 X77494 (external link) 241567 RBMS1 (external link) 0.261805 1.109
1267 GNF_FEMALE_GENES_h na H000626_01 Info Ribosomal protein L10 H000626_01 M64241 (external link) 29797 RPL10 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.2841001 0.912
1268 GNF_FEMALE_GENES_h na H001270_01 Info Interferon, gamma-inducible protein 16 H001270_01 M63838 (external link) 155530 IFI16 (external link) cell_signaling 0.2909837 1.116
1269 GNF_FEMALE_GENES_h na H008012_01 Info Ribosomal protein S24 H008012_01 M31520 (external link) 180450 RPS24 (external link) 0.3379111 1.131
1270 GNF_FEMALE_GENES_h na H001198_01 Info Homo sapiens, alpha-1 (VI) collagen H001198_01 M20776 (external link) 25459 0.3632512 1.1
1271 GNF_FEMALE_GENES_h na H006775_01 Info A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 H006775_01 AB037767 (external link) 8230 ADAMTS1 (external link) 0.3720854 1.072
1272 GNF_FEMALE_GENES_h na H005212_01 Info C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 2 (activation H005212_01 X96719 (external link) 85201 CLECSF2 (external link) 0.3801627 1.089
1273 GNF_FEMALE_GENES_h na H005723_01 Info Ribosomal protein L34 H005723_01 L38941 (external link) 250895 RPL34 (external link) 0.4130435 1.133
1274 GNF_FEMALE_GENES_h na H003115_01 Info Low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) H003115_01 X13916 (external link) 89137 LRP1 (external link) cell_cycle, cell_signaling, immunology 0.4443931 0.926
1275 GNF_FEMALE_GENES_h na H014105_01 Info Ribosomal protein L36a H014105_01 NM_001001 (external link) 118857 RPL36A (external link) 0.4522347 1.101
1276 GNF_FEMALE_GENES_h na H012632_01 Info Ribosomal protein L9 H012632_01 U09953 (external link) 157850 RPL9 (external link) 0.5126569 1.077
1277 GNF_FEMALE_GENES_h na H000213_01 Info Eukaryotic translation initiation factor 3, subunit 6 (48kD) H000213_01 U62962 (external link) 106673 EIF3S6 (external link) gene_regulation, immunology, transcription, tsonc 0.5258922 1.066
1278 GNF_FEMALE_GENES_h na H000034_01 Info Ribosomal protein L7 H000034_01 X57958 (external link) 153 RPL7 (external link) 0.5440511 1.085
1279 GNF_FEMALE_GENES_h na H007807_01 Info Ribosomal protein L39 H007807_01 D79205 (external link) 300141 RPL39 (external link) 0.550634 1.065
1280 GNF_FEMALE_GENES_h na H011160_01 Info Eukaryotic translation elongation factor 1 beta 1 H011160_01 X60656 (external link) 261802 EEF1B1 (external link) 0.5824813 1.068
1281 GNF_FEMALE_GENES_h na H002689_01 Info Ribosomal protein L15 H002689_01 L25899 (external link) 74267 RPL15 (external link) 0.6165764 0.94
1282 GNF_FEMALE_GENES_h na H012998_01 Info Homo sapiens cDNA FLJ11256 fis, clone PLACE1008925 H012998_01 AK002118 (external link) 272247 0.6438646 1.044
1283 GNF_FEMALE_GENES_h na H007375_01 Info Hypothetical protein DKFZp586F2423 H007375_01 AL080209 (external link) 13659 DKFZP586F2423 (external link) 0.6776451 0.96
1284 GNF_FEMALE_GENES_h na H015333_01 Info Ribosomal protein L35a H015333_01 NM_000996 (external link) 287361 RPL35A (external link) 0.7045738 1.05
1285 GNF_FEMALE_GENES_h na H000589_01 Info Cysteine-rich, angiogenic inducer, 61 H000589_01 Y11307 (external link) 8867 CYR61 (external link) 0.7640549 0.976
1286 GNF_FEMALE_GENES_h na H012850_01 Info Nucleosome assembly protein 1-like 1 H012850_01 AL162068 (external link) 179662 NAP1L1 (external link) 0.7805775 0.973
1287 GNF_FEMALE_GENES_h na H003196_01 Info Ribosomal protein L6 H003196_01 X69391 (external link) 174131 RPL6 (external link) 0.806836 1.029
1288 GNF_FEMALE_GENES_h na H006606_01 Info Ribosomal protein L24 H006606_01 M94314 (external link) 184582 RPL24 (external link) 0.8560724 1.02
1289 GNF_FEMALE_GENES_h na H009456_01 Info Ribosomal protein L17 H009456_01 X53777 (external link) 82202 RPL17 (external link) 0.8757496 0.983
1290 GNF_FEMALE_GENES_h na H012065_01 Info Ribosomal protein S4, X-linked H012065_01 M58458 (external link) 108124 RPS4X (external link) immunology 0.8900601 1.017
1291 GNF_FEMALE_GENES_h na H000071_01 Info Ribosomal protein S3A H000071_01 M84711 (external link) 77039 RPS3A (external link) 0.9635871 0.994
1292 GNF_FEMALE_GENES_h na H009310_01 Info Immunoglobulin superfamily containing leucine-rich repeat H009310_01 AB024536 (external link) 102171 ISLR (external link) 0.9743631 0.997
1293 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H003208_01 Info Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase H003208_01 NM_002408 (external link) 172195 MGAT2 (external link) N-Glycan biosynthesis 0.0033074 0.717
1294 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H016058_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 3 H016058_01 NM_003779 (external link) 321231 B4GALT3 (external link) Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.0064647 0.72
1295 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H003403_01 Info Mannosidase, alpha, class 2A, member 1 H003403_01 D63998 (external link) 32965 MAN2A1 (external link) N-Glycan biosynthesis 0.0334798 0.831
1296 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H001712_01 Info Dolichyl – diphosphooligosaccharide – protein glycosyltransferase H001712_01 D29643 (external link) 34789 DDOST (external link) N-Glycan biosynthesis 0.1164599 0.856
1297 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H006144_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 3 H006144_01 AF038661 (external link) 321231 B4GALT3 (external link) Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.1629007 1.121
1298 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H001158_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 1 H001158_01 D29805 (external link) 198248 B4GALT1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Galactose metabolism, Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.1752304 1.141
1299 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H014296_01 Info Hypothetical protein FLJ21924 H014296_01 NM_024774 (external link) 143509 FLJ21924 (external link) 0.2628233 0.878
1300 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H001166_01 Info Glucosidase I H001166_01 X87237 (external link) 83919 GCS1 (external link) ER associated degradation (ERAD) Pathway, N-Glycan biosynthesis 0.3340129 0.922
1301 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H001585_01 Info Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase H001585_01 NM_002406 (external link) 151513 MGAT1 (external link) N-Glycan biosynthesis 0.3439299 1.076
1302 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H016296_01 Info Dolichyl – diphosphooligosaccharide – protein glycosyltransferase H016296_01 NM_005216 (external link) 34789 DDOST (external link) N-Glycan biosynthesis 0.4721938 0.93
1303 MAP00510_N_Glycans_biosynthesis_h GenMAPP (external link) H002721_01 Info Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) H002721_01 X62822 (external link) 2554 SIAT1 (external link) angiogenesis, metastasis 0.8087218 1.023
1304 CR_PROTEIN_MOD_h PNAS_2010 H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 (external link) 87773 PRKACB (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1305 CR_PROTEIN_MOD_h PNAS_2010 H000599_01 Info Protein phosphatase 1D magnesium-dependent, delta isoform H000599_01 U78305 (external link) 100980 PPM1D (external link) 0.0049252 1.53
1306 CR_PROTEIN_MOD_h PNAS_2010 H000474_01 Info Testis-specific kinase 1 H000474_01 D50863 (external link) 79358 TESK1 (external link) cell_cycle, cell_signaling, signal_transduction 0.005093 1.591
1307 CR_PROTEIN_MOD_h PNAS_2010 H001868_01 Info Dual specificity phosphatase 9 H001868_01 Y08302 (external link) 144879 DUSP9 (external link) Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.0053314 0.725
1308 CR_PROTEIN_MOD_h PNAS_2010 H002290_01 Info Acid phosphatase 5, tartrate resistant H002290_01 NM_001611 (external link) 1211 ACP5 (external link) gamma-Hexachlorocyclohexane degradation, Riboflavin metabolism, cell_cycle, cell_signaling, immunology 0.0064683 1.315
1309 CR_PROTEIN_MOD_h PNAS_2010 H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 (external link) 80887 LYN (external link) BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
1310 CR_PROTEIN_MOD_h PNAS_2010 H002847_01 Info Protein tyrosine phosphatase, receptor type, B H002847_01 X54131 (external link) 123641 PTPRB (external link) Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling 0.0110757 1.299
1311 CR_PROTEIN_MOD_h PNAS_2010 H002041_01 Info Protein kinase, cAMP-dependent, catalytic, alpha H002041_01 X07767 (external link) 77271 PRKACA (external link) Activation of cAMP-dependent protein kinase, PKA, AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0156701 1.282
1312 CR_PROTEIN_MOD_h PNAS_2010 H003224_01 Info Ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) H003224_01 M30496 (external link) 77917 UCHL3 (external link) 0.0181978 0.767
1313 CR_PROTEIN_MOD_h PNAS_2010 H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 (external link) 86858 RPS6KB1 (external link) CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1314 CR_PROTEIN_MOD_h PNAS_2010 H003028_01 Info Protein tyrosine phosphatase, receptor type, M H003028_01 X58288 (external link) 154151 PTPRM (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.0218926 0.763
1315 CR_PROTEIN_MOD_h PNAS_2010 H008575_01 Info Protein phosphatase 6, catalytic subunit H008575_01 X92972 (external link) 279563 PPP6C (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.0235177 0.753
1316 CR_PROTEIN_MOD_h PNAS_2010 H002124_01 Info Protein phosphatase 1, catalytic subunit, gamma isoform H002124_01 X74008 (external link) 79081 PPP1CC (external link) cell_cycle, cell_signaling 0.02467 0.747
1317 CR_PROTEIN_MOD_h PNAS_2010 H003657_01 Info Protein kinase, interferon-inducible double stranded RNA dependent H003657_01 NM_002759 (external link) 274382 PRKR (external link) cell_cycle, cell_signaling, signal_transduction 0.0267646 1.238
1318 CR_PROTEIN_MOD_h PNAS_2010 H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1319 CR_PROTEIN_MOD_h PNAS_2010 H006644_01 Info Phosphorylase kinase, alpha 2 (liver) H006644_01 X80497 (external link) 54941 PHKA2 (external link) cell_cycle, cell_signaling, signal_transduction 0.0321533 1.233
1320 CR_PROTEIN_MOD_h PNAS_2010 H001785_01 Info Hepsin (transmembrane protease, serine 1) H001785_01 X07732 (external link) 823 HPN (external link) immunology 0.0349261 0.752
1321 CR_PROTEIN_MOD_h PNAS_2010 H002876_01 Info Protein tyrosine phosphatase, non-receptor type 2 H002876_01 M25393 (external link) 82829 PTPN2 (external link) cell_cycle, cell_signaling 0.0354884 0.704
1322 CR_PROTEIN_MOD_h PNAS_2010 H001127_01 Info Leukocyte tyrosine kinase H001127_01 D16105 (external link) 210 LTK (external link) cell_cycle, cell_signaling, immunology, signal_transduction 0.0368769 0.812
1323 CR_PROTEIN_MOD_h PNAS_2010 H000507_01 Info Tubulin-specific chaperone c H000507_01 U61234 (external link) 75064 TBCC (external link) cell_signaling, metastasis 0.0442081 1.496
1324 CR_PROTEIN_MOD_h PNAS_2010 H002194_01 Info Casein kinase 1, alpha 1 H002194_01 L37042 (external link) 283738 CSNK1A1 (external link) Deregulation of CDK5 in Alzheimer’s Disease, Hypoxia and p53 in the Cardiovascular system, NFAT and Hypertrophy of the heart (Transcription in the broken heart), WNT Signaling Pathway, cell_cycle, cell_signaling, signal_transduction 0.0461818 0.809
1325 CR_PROTEIN_MOD_h PNAS_2010 H000387_01 Info Cullin 2 H000387_01 U83410 (external link) 82919 CUL2 (external link) 0.0570922 0.832
1326 CR_PROTEIN_MOD_h PNAS_2010 H000521_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 2 H000521_01 X85106 (external link) 301664 RPS6KA2 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0604408 1.207
1327 CR_PROTEIN_MOD_h PNAS_2010 H000451_01 Info Protein tyrosine kinase 9 H000451_01 U02680 (external link) 82643 PTK9 (external link) cell_cycle, cell_signaling, signal_transduction 0.0657095 0.808
1328 CR_PROTEIN_MOD_h PNAS_2010 H003873_01 Info Protein tyrosine phosphatase, receptor type, K H003873_01 L77886 (external link) 79005 PTPRK (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.0658539 0.801
1329 CR_PROTEIN_MOD_h PNAS_2010 H001676_01 Info Protein kinase C, iota H001676_01 L33881 (external link) 1904 PRKCI (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0761126 0.777
1330 CR_PROTEIN_MOD_h PNAS_2010 H002475_01 Info Pim-1 oncogene H002475_01 M54915 (external link) 81170 PIM1 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0799298 1.166
1331 CR_PROTEIN_MOD_h PNAS_2010 H003808_01 Info V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog H003808_01 X06182 (external link) 81665 KIT (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Melanocyte Development and Pigmentation Pathway, Regulation of BAD phosphorylation, immunology, tsonc 0.0813112 1.349
1332 CR_PROTEIN_MOD_h PNAS_2010 H003804_01 Info PTK7 protein tyrosine kinase 7 H003804_01 U33635 (external link) 90572 PTK7 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling, signal_transduction 0.0836802 0.82
1333 CR_PROTEIN_MOD_h PNAS_2010 H001730_01 Info Dual specificity phosphatase 7 H001730_01 X93921 (external link) 296938 DUSP7 (external link) 0.1170133 1.223
1334 CR_PROTEIN_MOD_h PNAS_2010 H002155_01 Info Casein kinase 1, delta H002155_01 U29171 (external link) 75852 CSNK1D (external link) Regulation of ck1/cdk5 by type 1 glutamate receptors, cell_cycle, cell_signaling, signal_transduction 0.12119 0.868
1335 CR_PROTEIN_MOD_h PNAS_2010 H003207_01 Info V-abl Abelson murine leukemia viral oncogene homolog 1 H003207_01 NM_005157 (external link) 146355 ABL1 (external link) cell_signaling, signal_transduction, tsonc 0.1292454 0.826
1336 CR_PROTEIN_MOD_h PNAS_2010 H015696_01 Info Cathepsin B H015696_01 NM_001908 (external link) 297939 CTSB (external link) immunology, misc 0.1306532 1.18
1337 CR_PROTEIN_MOD_h PNAS_2010 H001631_01 Info Protein phosphatase 4 (formerly X), catalytic subunit H001631_01 AF097996 (external link) 2903 PPP4C (external link) cell_cycle, cell_signaling 0.1363218 1.131
1338 CR_PROTEIN_MOD_h PNAS_2010 H002356_01 Info Alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD1 H002356_01 M22324 (external link) 1239 ANPEP (external link) Dendritic cells in regulating TH1 and TH2 Development, SARS Coronavirus Protease, Glutathione metabolism, angiogenesis, immunology, metastasis 0.1526923 1.194
1339 CR_PROTEIN_MOD_h PNAS_2010 H002669_01 Info LIM domain kinase 2 H002669_01 NM_016733 (external link) 278027 LIMK2 (external link) cell_cycle, cell_signaling, signal_transduction 0.1587394 1.231
1340 CR_PROTEIN_MOD_h PNAS_2010 H001679_01 Info Protein phosphatase, EF hand calcium-binding domain 1 H001679_01 X97867 (external link) 211589 PPEF1 (external link) 0.1646513 0.872
1341 CR_PROTEIN_MOD_h PNAS_2010 H001296_01 Info Protein tyrosine phosphatase, non-receptor type 7 H001296_01 M64322 (external link) 35 PTPN7 (external link) T Cell Receptor Signaling Pathway, cell_cycle, cell_signaling 0.165907 0.84
1342 CR_PROTEIN_MOD_h PNAS_2010 H000198_01 Info V-ski avian sarcoma viral oncogene homolog H000198_01 X15218 (external link) 2969 SKI (external link) tsonc 0.1691582 0.874
1343 CR_PROTEIN_MOD_h PNAS_2010 H003518_01 Info V-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) H003518_01 M35296 (external link) 121521 ABL2 (external link) cell_cycle, cell_signaling, signal_transduction, tsonc 0.1694499 1.149
1344 CR_PROTEIN_MOD_h PNAS_2010 H000558_01 Info Serine/threonine kinase 4 H000558_01 U60207 (external link) 35140 STK4 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.1725076 0.861
1345 CR_PROTEIN_MOD_h PNAS_2010 H003621_01 Info Fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94) H003621_01 J03358 (external link) 121558 FER (external link) signal_transduction, tsonc 0.1752525 0.868
1346 CR_PROTEIN_MOD_h PNAS_2010 H008496_01 Info Cullin 1 H008496_01 AF062536 (external link) 14541 CUL1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.1769614 1.122
1347 CR_PROTEIN_MOD_h PNAS_2010 H000644_01 Info Protein phosphatase 2, regulatory subunit B (B56), alpha isoform H000644_01 L42373 (external link) 155079 PPP2R5A (external link) cell_cycle, cell_signaling, signal_transduction 0.1872145 0.884
1348 CR_PROTEIN_MOD_h PNAS_2010 H001706_01 Info Protein tyrosine phosphatase, non-receptor type 3 H001706_01 M64572 (external link) 153932 PTPN3 (external link) cell_cycle, cell_signaling 0.2117298 1.123
1349 CR_PROTEIN_MOD_h PNAS_2010 H003820_01 Info Lymphocyte-specific protein tyrosine kinase H003820_01 X05027 (external link) 1765 LCK (external link) Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc 0.2266863 0.873
1350 CR_PROTEIN_MOD_h PNAS_2010 H002457_01 Info Protein kinase C, zeta H002457_01 Z15108 (external link) 78793 PRKCZ (external link) Phosphoinositides and their downstream targets., Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2375152 0.898
1351 CR_PROTEIN_MOD_h PNAS_2010 H003441_01 Info Breakpoint cluster region H003441_01 X02596 (external link) 234799 BCR (external link) Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc 0.2521813 1.116
1352 CR_PROTEIN_MOD_h PNAS_2010 H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 (external link) 154729 PDPK1 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1353 CR_PROTEIN_MOD_h PNAS_2010 H000682_01 Info Phosphorylase kinase, gamma 2 (testis) H000682_01 M31606 (external link) 196177 PHKG2 (external link) cell_cycle, cell_signaling, signal_transduction 0.2546262 1.097
1354 CR_PROTEIN_MOD_h PNAS_2010 H001876_01 Info 3′-phosphoadenosine 5′-phosphosulfate synthase 1 H001876_01 AF105227 (external link) 3833 PAPSS1 (external link) Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism 0.2713835 0.89
1355 CR_PROTEIN_MOD_h PNAS_2010 H001393_01 Info Protein tyrosine phosphatase type IVA, member 2 H001393_01 AF208850 (external link) 82911 PTP4A2 (external link) 0.2727324 0.892
1356 CR_PROTEIN_MOD_h PNAS_2010 H002947_01 Info Protein phosphatase 1, catalytic subunit, alpha isoform H002947_01 S57501 (external link) 183994 PPP1CA (external link) cell_cycle, cell_signaling 0.2817559 1.112
1357 CR_PROTEIN_MOD_h PNAS_2010 H003484_01 Info B lymphoid tyrosine kinase H003484_01 S76617 (external link) 2243 BLK (external link) cell_cycle, cell_signaling, immunology, signal_transduction 0.3077997 1.161
1358 CR_PROTEIN_MOD_h PNAS_2010 H000392_01 Info Human renal cell carcinoma antigen RAGE-4 mRNA, complete putative CDS H000392_01 U46194 (external link) 189253 Phosphatidylinositol signaling system 0.3127126 0.9
1359 CR_PROTEIN_MOD_h PNAS_2010 H001273_01 Info BMX non-receptor tyrosine kinase H001273_01 AF045459 (external link) 27372 BMX (external link) cell_cycle, cell_signaling, signal_transduction 0.3145394 0.907
1360 CR_PROTEIN_MOD_h PNAS_2010 H002235_01 Info Ubiquitin specific protease 6 (Tre-2 oncogene) H002235_01 X63547 (external link) 111065 USP6 (external link) tsonc 0.3321253 0.887
1361 CR_PROTEIN_MOD_h PNAS_2010 H000617_01 Info Protein phosphatase 2, regulatory subunit B (B56), beta isoform H000617_01 L42374 (external link) 75199 PPP2R5B (external link) cell_cycle, cell_signaling, signal_transduction 0.3383822 1.102
1362 CR_PROTEIN_MOD_h PNAS_2010 H001979_01 Info Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) H001979_01 M29551 (external link) 151531 PPP3CB (external link) cell_cycle, cell_signaling 0.3386238 0.898
1363 CR_PROTEIN_MOD_h PNAS_2010 H002948_01 Info Ubiquitin specific protease 4 (proto-oncogene) H002948_01 U20657 (external link) 77500 USP4 (external link) tsonc 0.3395867 1.14
1364 CR_PROTEIN_MOD_h PNAS_2010 H003637_01 Info Protein tyrosine phosphatase, non-receptor type 12 H003637_01 M93425 (external link) 62 PTPN12 (external link) cell_cycle, cell_signaling 0.3503541 1.098
1365 CR_PROTEIN_MOD_h PNAS_2010 H003877_01 Info Paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein) H003877_01 X17094 (external link) 59242 PACE (external link) Proteolysis and Signaling Pathway of Notch 0.3592119 1.111
1366 CR_PROTEIN_MOD_h PNAS_2010 H001703_01 Info Protein phosphatase 2 (formerly 2A), regulatory subunit B” (PR 72), alpha isoform and (PR 130), bet H001703_01 L07590 (external link) 28219 PPP2R3 (external link) 0.3677168 0.922
1367 CR_PROTEIN_MOD_h PNAS_2010 H015748_01 Info Serine/threonine kinase 11 (Peutz-Jeghers syndrome) H015748_01 NM_000455 (external link) 301772 STK11 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.3807438 1.093
1368 CR_PROTEIN_MOD_h PNAS_2010 H003351_01 Info Protein kinase, DNA-activated, catalytic polypeptide H003351_01 U47077 (external link) 155637 PRKDC (external link) Cell Cycle: G2/M Checkpoint, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system, DNA_damage, immunology 0.3847336 0.919
1369 CR_PROTEIN_MOD_h PNAS_2010 H001347_01 Info Protein tyrosine phosphatase, non-receptor type 18 (brain-derived) H001347_01 X79568 (external link) 278597 PTPN18 (external link) 0.3923457 0.914
1370 CR_PROTEIN_MOD_h PNAS_2010 H015456_01 Info Homo sapiens mRNA for FLJ00047 protein, partial CDS H015456_01 AK024455 (external link) 287753 Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.4000256 1.107
1371 CR_PROTEIN_MOD_h PNAS_2010 H000645_01 Info Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 (external link) 183037 PRKAR1A (external link) Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction 0.4305614 0.935
1372 CR_PROTEIN_MOD_h PNAS_2010 H003529_01 Info ELK3, ETS-domain protein (SRF accessory protein 2) H003529_01 Z36715 (external link) 121529 ELK3 (external link) tsonc 0.4403881 0.913
1373 CR_PROTEIN_MOD_h PNAS_2010 H015286_01 Info Homo sapiens PAK2 mRNA, complete CDS H015286_01 AF092132 (external link) 284275 FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAP Kinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system 0.4868167 1.068
1374 CR_PROTEIN_MOD_h PNAS_2010 H007319_01 Info Histone deacetylase 5 H007319_01 NM_005474 (external link) 9028 HDAC5 (external link) Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Regulation of PGC-1a 0.5427846 1.062
1375 CR_PROTEIN_MOD_h PNAS_2010 H005412_01 Info Protein phosphatase 2, regulatory subunit B (B56), delta isoform H005412_01 L76702 (external link) 118244 PPP2R5D (external link) cell_cycle, cell_signaling, signal_transduction 0.5741013 1.063
1376 CR_PROTEIN_MOD_h PNAS_2010 H013300_01 Info Pyruvate dehydrogenase kinase, isoenzyme 2 H013300_01 L42451 (external link) 92261 PDK2 (external link) mTOR Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, cell_cycle, cell_signaling, signal_transduction 0.5991595 0.949
1377 CR_PROTEIN_MOD_h PNAS_2010 H002812_01 Info Protein tyrosine phosphatase, receptor type, C H002812_01 Y00062 (external link) 170121 PTPRC (external link) Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology 0.6066202 1.093
1378 CR_PROTEIN_MOD_h PNAS_2010 H001923_01 Info Protein kinase, cGMP-dependent, type I H001923_01 Y07512 (external link) 2689 PRKG1 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.6231152 0.956
1379 CR_PROTEIN_MOD_h PNAS_2010 H001896_01 Info Protein phosphatase 1, catalytic subunit, beta isoform H001896_01 X80910 (external link) 21537 PPP1CB (external link) cell_cycle, cell_signaling 0.6410125 0.947
1380 CR_PROTEIN_MOD_h PNAS_2010 H002495_01 Info Protein tyrosine phosphatase, receptor type, N H002495_01 L18983 (external link) 89655 PTPRN (external link) cell_cycle, cell_signaling 0.6620657 0.963
1381 CR_PROTEIN_MOD_h PNAS_2010 H003698_01 Info Protein tyrosine phosphatase, non-receptor type 1 H003698_01 M31724 (external link) 155894 PTPN1 (external link) cell_cycle, cell_signaling 0.6633733 1.054
1382 CR_PROTEIN_MOD_h PNAS_2010 H001721_01 Info Protein phosphatase 5, catalytic subunit H001721_01 X89416 (external link) 75180 PPP5C (external link) 0.6792992 1.036
1383 CR_PROTEIN_MOD_h PNAS_2010 H000479_01 Info Dual specificity phosphatase 8 H000479_01 U27193 (external link) 41688 DUSP8 (external link) Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.7214843 1.03
1384 CR_PROTEIN_MOD_h PNAS_2010 H007840_01 Info KIAA0508 protein H007840_01 AB007977 (external link) 270010 KIAA0508 (external link) tsonc 0.7438349 1.027
1385 CR_PROTEIN_MOD_h PNAS_2010 H001646_01 Info Dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) H001646_01 AL049417 (external link) 181046 DUSP3 (external link) cell_cycle, cell_signaling 0.7811469 0.968
1386 CR_PROTEIN_MOD_h PNAS_2010 H001681_01 Info Protein kinase C, theta H001681_01 L01087 (external link) 211593 PRKCQ (external link) Keratinocyte Differentiation, cell_cycle, cell_signaling, immunology, signal_transduction 0.8037373 1.019
1387 CR_PROTEIN_MOD_h PNAS_2010 H002721_01 Info Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) H002721_01 X62822 (external link) 2554 SIAT1 (external link) angiogenesis, metastasis 0.8087218 1.023
1388 CR_PROTEIN_MOD_h PNAS_2010 H003160_01 Info RYK receptor-like tyrosine kinase H003160_01 S59184 (external link) 79350 RYK (external link) cell_cycle, cell_signaling, signal_transduction 0.8388374 0.98
1389 CR_PROTEIN_MOD_h PNAS_2010 H001596_01 Info Protein kinase C, gamma H001596_01 Z15114 (external link) 2890 PRKCG (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.8498034 1.018
1390 CR_PROTEIN_MOD_h PNAS_2010 H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 (external link) 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1391 CR_PROTEIN_MOD_h PNAS_2010 H003541_01 Info Protein tyrosine phosphatase, non-receptor type 9 H003541_01 M83738 (external link) 147663 PTPN9 (external link) cell_cycle, cell_signaling 0.8676444 1.016
1392 CR_PROTEIN_MOD_h PNAS_2010 H002806_01 Info Protein tyrosine phosphatase, receptor type, N polypeptide 2 H002806_01 U66702 (external link) 74624 PTPRN2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, cell_cycle, cell_signaling 0.8826274 1.014
1393 CR_PROTEIN_MOD_h PNAS_2010 H003074_01 Info Protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform H003074_01 M64929 (external link) 179574 PPP2R2A (external link) cell_cycle, cell_signaling 0.9053085 0.989
1394 CR_PROTEIN_MOD_h PNAS_2010 H001766_01 Info Protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) H001766_01 M68941 (external link) 73826 PTPN4 (external link) cell_cycle, cell_signaling 0.9219914 0.991
1395 CR_PROTEIN_MOD_h PNAS_2010 H001353_01 Info Casein kinase 1, epsilon H001353_01 AB024597 (external link) 79658 CSNK1E (external link) Circadian Rhythms, cell_cycle, cell_signaling, signal_transduction 0.9225285 1.008
1396 CR_PROTEIN_MOD_h PNAS_2010 H000464_01 Info Protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform H000464_01 M65254 (external link) 108705 PPP2R1B (external link) cell_cycle, cell_signaling 0.9562489 0.994
1397 CR_PROTEIN_MOD_h PNAS_2010 H003151_01 Info E1A binding protein p300 H003151_01 U01877 (external link) 25272 EP300 (external link) Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
1398 CR_PROTEIN_MOD_h PNAS_2010 H001715_01 Info Dual specificity phosphatase 4 H001715_01 AL137704 (external link) 2359 DUSP4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling 0.9634643 1.004
1399 CR_PROTEIN_MOD_h PNAS_2010 H001448_01 Info HtrA-like serine protease H001448_01 NM_013247 (external link) 115721 OMI (external link) 0.9961185 1
1400 p27Pathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
1401 p27Pathway_h BioCarta H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
1402 p27Pathway_h BioCarta H002802_01 Info Neural precursor cell expressed, developmentally down-regulated 8 H002802_01 D23662 (external link) 75512 NEDD8 (external link) Regulation of p27 Phosphorylation during Cell Cycle Progression 0.0045178 1.293
1403 p27Pathway_h BioCarta H002323_01 Info Cyclin E1 H002323_01 M74093 (external link) 9700 CCNE1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle 0.1107382 0.884
1404 p27Pathway_h BioCarta H008496_01 Info Cullin 1 H008496_01 AF062536 (external link) 14541 CUL1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.1769614 1.122
1405 p27Pathway_h BioCarta H003109_01 Info CDC28 protein kinase 1 H003109_01 X54941 (external link) 77550 CKS1 (external link) Regulation of p27 Phosphorylation during Cell Cycle Progression 0.3099586 1.102
1406 p27Pathway_h BioCarta H009086_01 Info S-phase kinase-associated protein 2 (p45) H009086_01 U33761 (external link) 23348 SKP2 (external link) Cell Cycle: G1/S Check Point , E2F1 Destruction Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.330649 1.089
1407 p27Pathway_h BioCarta H008244_01 Info S-phase kinase-associated protein 1A (p19A) H008244_01 U33760 (external link) 227950 SKP1A (external link) Cyclin E Destruction Pathway, E2F1 Destruction Pathway, ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.4920203 0.951
1408 p27Pathway_h BioCarta H011149_01 Info Ring-box 1 H011149_01 NM_014248 (external link) 279919 RBX1 (external link) ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.603709 1.055
1409 p27Pathway_h BioCarta H003162_01 Info Transcription factor Dp-1 H003162_01 L23959 (external link) 279576 TFDP1 (external link) Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression 0.6646128 0.958
1410 SA_PTEN_PATHWAY_h SigmaAldrich H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1411 SA_PTEN_PATHWAY_h SigmaAldrich H003191_01 Info Retinoblastoma-like 2 (p130) H003191_01 X76061 (external link) 79362 RBL2 (external link) METS affect on Macrophage Differentiation 0.00669 0.724
1412 SA_PTEN_PATHWAY_h SigmaAldrich H002573_01 Info Protein tyrosine kinase 2 beta H002573_01 U43522 (external link) 20313 PTK2B (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction 0.0091935 1.367
1413 SA_PTEN_PATHWAY_h SigmaAldrich H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 (external link) 162808 PIK3CD (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1414 SA_PTEN_PATHWAY_h SigmaAldrich H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1415 SA_PTEN_PATHWAY_h SigmaAldrich H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1416 SA_PTEN_PATHWAY_h SigmaAldrich H004340_01 Info 3′(2′), 5′-bisphosphate nucleotidase 1 H004340_01 NM_006085 (external link) 271752 BPNT1 (external link) Sulfur metabolism 0.1694685 1.176
1417 SA_PTEN_PATHWAY_h SigmaAldrich H002970_01 Info Integrin-linked kinase H002970_01 U40282 (external link) 6196 ILK (external link) PTEN dependent cell cycle arrest and apoptosis, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.1701136 1.128
1418 SA_PTEN_PATHWAY_h SigmaAldrich H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1419 SA_PTEN_PATHWAY_h SigmaAldrich H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1420 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H003000_01 Info RAB5A, member RAS oncogene family H003000_01 M28215 (external link) 73957 RAB5A (external link) Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc 0.0003278 0.591
1421 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H002296_01 Info RAB5B, member RAS oncogene family H002296_01 X54871 (external link) 77690 RAB5B (external link) tsonc 0.0071339 1.264
1422 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001623_01 Info RAB3A, member RAS oncogene family H001623_01 M28210 (external link) 27744 RAB3A (external link) Rab GTPases Mark Targets In The Endocytotic Machinery, tsonc 0.0155278 0.773
1423 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001739_01 Info Adaptor-related protein complex 2, mu 1 subunit H001739_01 D63475 (external link) 152936 AP2M1 (external link) 0.0326931 0.787
1424 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001641_01 Info RAB5C, member RAS oncogene family H001641_01 U18420 (external link) 479 RAB5C (external link) 0.124762 1.135
1425 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001711_01 Info RAB3B, member RAS oncogene family H001711_01 M28214 (external link) 123072 RAB3B (external link) tsonc 0.1338843 0.849
1426 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001622_01 Info RAB31, member RAS oncogene family H001622_01 U59877 (external link) 223025 RAB31 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.152499 1.183
1427 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001723_01 Info RAB4, member RAS oncogene family H001723_01 M28211 (external link) 119007 RAB4 (external link) Rab GTPases Mark Targets In The Endocytotic Machinery 0.1838619 0.841
1428 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001731_01 Info RAB6A, member RAS oncogene family H001731_01 AF052130 (external link) 5636 RAB6A (external link) Rab GTPases Mark Targets In The Endocytotic Machinery 0.2234269 1.121
1429 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001719_01 Info Golgi autoantigen, golgin subfamily a, 4 H001719_01 X82834 (external link) 183773 GOLGA4 (external link) 0.2608724 0.87
1430 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H002973_01 Info RAB1, member RAS oncogene family H002973_01 M28209 (external link) 3642 RAB1 (external link) Rab GTPases Mark Targets In The Endocytotic Machinery 0.292711 1.103
1431 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H005768_01 Info ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha) H005768_01 X82206 (external link) 153961 ACTR1A (external link) 0.2959858 1.106
1432 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H007601_01 Info RAB27A, member RAS oncogene family H007601_01 U57094 (external link) 50477 RAB27A (external link) Rab GTPases Mark Targets In The Endocytotic Machinery, tsonc 0.6368779 1.053
1433 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001985_01 Info RAB13, member RAS oncogene family H001985_01 X75593 (external link) 151536 RAB13 (external link) tsonc 0.6547022 0.954
1434 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H012333_01 Info RAB27B, member RAS oncogene family H012333_01 NM_004163 (external link) 97189 RAB27B (external link) tsonc 0.6900974 0.957
1435 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H001910_01 Info RAB11A, member RAS oncogene family H001910_01 AF000231 (external link) 75618 RAB11A (external link) Rab GTPases Mark Targets In The Endocytotic Machinery, tsonc 0.7408236 1.034
1436 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H010181_01 Info RAB7, member RAS oncogene family-like 1 H010181_01 D84488 (external link) 115325 RAB7L1 (external link) tsonc 0.7680291 0.961
1437 CR_TRANSPORT_OF_VESICLES_h PNAS_2015 H009706_01 Info RAB1, member RAS oncogene family H009706_01 AL050268 (external link) 3642 RAB1 (external link) Rab GTPases Mark Targets In The Endocytotic Machinery 0.7686339 0.971
1438 il1rPathway_h BioCarta H003352_01 Info Interleukin 1 receptor, type I H003352_01 M27492 (external link) 82112 IL1R1 (external link) NF-kB Signaling Pathway, Signal transduction through IL1R, immunology 0.000502 0.677
1439 il1rPathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 (external link) 180533 MAP2K3 (external link) fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
1440 il1rPathway_h BioCarta H003232_01 Info Mitogen-activated protein kinase kinase kinase 14 H003232_01 Y10256 (external link) 47007 MAP3K14 (external link) CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.005309 0.755
1441 il1rPathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1442 il1rPathway_h BioCarta H000657_01 Info Myeloid differentiation primary response gene (88) H000657_01 U70451 (external link) 82116 MYD88 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, Toll-Like Receptor Pathway, apoptosis, immunology, misc 0.0732203 1.23
1443 il1rPathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1444 il1rPathway_h BioCarta H007884_01 Info TOLLIP protein H007884_01 AJ242972 (external link) 25413 LOC54472 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Signal transduction through IL1R, Toll-Like Receptor Pathway 0.3826742 0.898
1445 il1rPathway_h BioCarta H001957_01 Info Interleukin 1, beta H001957_01 M15330 (external link) 126256 IL1B (external link) IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology 0.4390274 1.089
1446 il1rPathway_h BioCarta H006060_01 Info ECSIT H006060_01 AF243044 (external link) 22199 LOC51295 (external link) Signal transduction through IL1R, Toll-Like Receptor Pathway 0.525719 1.065
1447 il1rPathway_h BioCarta H003110_01 Info Interleukin 6 (interferon, beta 2) H003110_01 X04430 (external link) 93913 IL6 (external link) Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology 0.680804 1.036
1448 il1rPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1449 il1rPathway_h BioCarta H002076_01 Info Interleukin-1 receptor-associated kinase 1 H002076_01 L76191 (external link) 182018 IRAK1 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NF-kB Signaling Pathway, Toll-Like Receptor Pathway, immunology, signal_transduction 0.8472418 0.982
1450 il1rPathway_h BioCarta H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 (external link) 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1451 il1rPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1452 il1rPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1453 tollPathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 (external link) 180533 MAP2K3 (external link) fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
1454 tollPathway_h BioCarta H003232_01 Info Mitogen-activated protein kinase kinase kinase 14 H003232_01 Y10256 (external link) 47007 MAP3K14 (external link) CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.005309 0.755
1455 tollPathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1456 tollPathway_h BioCarta H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1457 tollPathway_h BioCarta H003657_01 Info Protein kinase, interferon-inducible double stranded RNA dependent H003657_01 NM_002759 (external link) 274382 PRKR (external link) cell_cycle, cell_signaling, signal_transduction 0.0267646 1.238
1458 tollPathway_h BioCarta H000657_01 Info Myeloid differentiation primary response gene (88) H000657_01 U70451 (external link) 82116 MYD88 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, Toll-Like Receptor Pathway, apoptosis, immunology, misc 0.0732203 1.23
1459 tollPathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1460 tollPathway_h BioCarta H000042_01 Info Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma H000042_01 AF074382 (external link) 43505 IKBKG (external link) CD40L Signaling Pathway, NF-kB Signaling Pathway, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway 0.2784213 1.13
1461 tollPathway_h BioCarta H007884_01 Info TOLLIP protein H007884_01 AJ242972 (external link) 25413 LOC54472 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Signal transduction through IL1R, Toll-Like Receptor Pathway 0.3826742 0.898
1462 tollPathway_h BioCarta H006851_01 Info TAK1-binding protein 2; KIAA0733 protein H006851_01 AL117407 (external link) 109727 KIAA0733 (external link) Toll-Like Receptor Pathway 0.4908732 1.066
1463 tollPathway_h BioCarta H006060_01 Info ECSIT H006060_01 AF243044 (external link) 22199 LOC51295 (external link) Signal transduction through IL1R, Toll-Like Receptor Pathway 0.525719 1.065
1464 tollPathway_h BioCarta H011421_01 Info Toll-like receptor 3 H011421_01 U88879 (external link) 29499 TLR3 (external link) Toll-Like Receptor Pathway, immunology 0.5596679 1.057
1465 tollPathway_h BioCarta H006116_01 Info MD-2 protein H006116_01 AB018549 (external link) 69328 MD-2 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Toll-Like Receptor Pathway 0.661613 1.048
1466 tollPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1467 tollPathway_h BioCarta H002076_01 Info Interleukin-1 receptor-associated kinase 1 H002076_01 L76191 (external link) 182018 IRAK1 (external link) Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NF-kB Signaling Pathway, Toll-Like Receptor Pathway, immunology, signal_transduction 0.8472418 0.982
1468 tollPathway_h BioCarta H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 (external link) 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1469 tollPathway_h BioCarta H002350_01 Info Peroxisome proliferative activated receptor, alpha H002350_01 L02932 (external link) 998 PPARA (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway 0.8655149 1.015
1470 tollPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1471 tollPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1472 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000616_01 Info Nucleoside phosphorylase H000616_01 X00737 (external link) 75514 NP (external link) Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism, gene_regulation, immunology, transcription 0.0005739 0.632
1473 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002879_01 Info Polymerase (DNA directed), beta H002879_01 D29013 (external link) 180107 POLB (external link) DNA polymerase, Purine metabolism, Pyrimidine metabolism, cell_cycle, DNA_damage, DNA_replication, immunology 0.0052758 0.781
1474 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H001903_01 Info Polymerase (DNA directed), gamma H001903_01 X98093 (external link) 80961 POLG (external link) DNA polymerase, Purine metabolism, Pyrimidine metabolism 0.0148856 0.783
1475 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002569_01 Info Thymidine kinase 1, soluble H002569_01 K02581 (external link) 105097 TK1 (external link) Pyrimidine metabolism, gene_regulation, immunology, pharmacology, transcription 0.0152534 1.253
1476 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000456_01 Info Adenylate kinase 3 H000456_01 X60673 (external link) 274691 AK3 (external link) Pyrimidine metabolism, cell_cycle, cell_signaling, signal_transduction 0.0174112 0.738
1477 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002908_01 Info Ribonucleotide reductase M1 polypeptide H002908_01 X59543 (external link) 2934 RRM1 (external link) Purine metabolism, Pyrimidine metabolism, immunology, pharmacology 0.0183576 0.781
1478 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H007908_01 Info Polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) H007908_01 Z47727 (external link) 150675 POLR2K (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.0188042 0.756
1479 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000522_01 Info Cytidine deaminase H000522_01 L27943 (external link) 72924 CDA (external link) Pyrimidine metabolism, immunology, pharmacology 0.0460601 1.313
1480 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H007101_01 Info Polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) H007101_01 L37127 (external link) 80475 POLR2J (external link) 0.0526802 1.218
1481 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H003792_01 Info Polymerase (DNA directed), alpha H003792_01 X06745 (external link) 267289 POLA (external link) DNA polymerase, Purine metabolism, Pyrimidine metabolism, DNA_replication 0.072381 0.83
1482 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002687_01 Info Ribonucleotide reductase M2 polypeptide H002687_01 X59618 (external link) 75319 RRM2 (external link) Purine metabolism, Pyrimidine metabolism, pharmacology 0.0826808 0.823
1483 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H011566_01 Info Homo sapiens mutant DNA polymerase beta mRNA, partial CDS H011566_01 S69873 (external link) 241525 DNA polymerase, Purine metabolism, Pyrimidine metabolism, cell_cycle, DNA_damage, DNA_replication, immunology 0.096998 0.865
1484 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002522_01 Info Dihydropyrimidine dehydrogenase H002522_01 U20938 (external link) 1602 DPYD (external link) beta-Alanine metabolism, Pantothenate and CoA biosynthesis, Pyrimidine metabolism, immunology, pharmacology 0.104101 0.85
1485 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000394_01 Info Deoxycytidine kinase H000394_01 M60527 (external link) 709 DCK (external link) Purine metabolism, Pyrimidine metabolism, gene_regulation, pharmacology, transcription 0.1931198 0.887
1486 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000074_01 Info Polymerase (DNA directed), delta 2, regulatory subunit (50kD) H000074_01 U21090 (external link) 74598 POLD2 (external link) DNA polymerase, Purine metabolism, Pyrimidine metabolism 0.203416 0.871
1487 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000658_01 Info Uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5′-decarboxylase) H000658_01 J03626 (external link) 2057 UMPS (external link) Pyrimidine metabolism, immunology, pharmacology 0.2195884 1.099
1488 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H000484_01 Info CTP synthase H000484_01 X52142 (external link) 251871 CTPS (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Pyrimidine metabolism, gene_regulation, transcription 0.2236373 0.879
1489 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H010908_01 Info Polymerase (RNA) II (DNA directed) polypeptide E (25kD) H010908_01 D38251 (external link) 24301 POLR2E (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.2811044 1.09
1490 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H006451_01 Info Polymerase (RNA) II (DNA directed) polypeptide H H006451_01 U37689 (external link) 3128 POLR2H (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.3071417 0.912
1491 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H016370_01 Info Polymerase (RNA) II (DNA directed) polypeptide I (14.5kD) H016370_01 NM_006233 (external link) 47062 POLR2I (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.3118426 1.12
1492 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H007868_01 Info Similar to DNA-directed RNA polymerase I (135 kDa) H007868_01 AK001678 (external link) 86337 FLJ10816 (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.3875312 1.072
1493 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H005570_01 Info Polymerase (RNA) II (DNA directed) polypeptide B (140kD) H005570_01 X63563 (external link) 296014 POLR2B (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.4005386 0.927
1494 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H008768_01 Info Polymerase (RNA) II (DNA directed) polypeptide A (220kD) H008768_01 X63564 (external link) 171880 POLR2A (external link) CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Repression of Pain Sensation by the Transcriptional Regulator DREAM, Telomeres, Telomerase, Cellular Aging, and Immortality, The information-processing pathway at the IFN-beta enhancer, Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.4709936 0.933
1495 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H006464_01 Info Polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) H006464_01 U37690 (external link) 71618 POLR2L (external link) Purine metabolism, Pyrimidine metabolism, RNA polymerase 0.5110537 0.933
1496 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H008686_01 Info DUTP pyrophosphatase H008686_01 U31930 (external link) 82113 DUT (external link) Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Pyrimidine metabolism, gene_regulation, transcription 0.6087897 1.051
1497 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002572_01 Info Non-metastatic cells 2, protein (NM23B) expressed in H002572_01 M36981 (external link) 275163 NME2 (external link) cell_cycle, cell_signaling, signal_transduction 0.6557968 0.941
1498 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002195_01 Info Non-metastatic cells 1, protein (NM23A) expressed in H002195_01 X17620 (external link) 118638 NME1 (external link) Endocytotic role of NDK, Phosphins and Dynamin, Granzyme A mediated Apoptosis Pathway, Purine metabolism, Pyrimidine metabolism, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.6910793 0.967
1499 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H002094_01 Info Thymidylate synthetase H002094_01 X02308 (external link) 82962 TYMS (external link) One carbon pool by folate, Pyrimidine metabolism, metabolism, pharmacology 0.6945693 1.041
1500 MAP00240_Pyrimidine_metabolism_h GenMAPP (external link) H007289_01 Info Insulin-like growth factor binding protein 7 H007289_01 S75725 (external link) 119206 IGFBP7 (external link) 0.80895 1.034
1501 g2Pathway_h BioCarta H000208_01 Info Breast cancer 1, early onset H000208_01 NM_007295 (external link) 194143 BRCA1 (external link) ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc 0.009032 0.746
1502 g2Pathway_h BioCarta H002092_01 Info Ataxia telangiectasia and Rad3 related H002092_01 U49844 (external link) 77613 ATR (external link) Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology 0.0105491 0.753
1503 g2Pathway_h BioCarta H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 (external link) 149957 RPS6KA1 (external link) Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1504 g2Pathway_h BioCarta H001323_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide H001323_01 X56468 (external link) 74405 YWHAQ (external link) Cell Cycle: G2/M Checkpoint 0.0151437 0.755
1505 g2Pathway_h BioCarta H002304_01 Info Cell division cycle 25B H002304_01 S78187 (external link) 153752 CDC25B (external link) 0.0167858 0.8
1506 g2Pathway_h BioCarta H003739_01 Info Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 (external link) 184572 CDC2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle 0.0222229 0.733
1507 g2Pathway_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 (external link) 1846 TP53 (external link) Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
1508 g2Pathway_h BioCarta H003759_01 Info Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) H003759_01 U40343 (external link) 29656 CDKN2D (external link) Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation 0.0311312 1.253
1509 g2Pathway_h BioCarta H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
1510 g2Pathway_h BioCarta H002371_01 Info Cyclin B1 H002371_01 M25753 (external link) 23960 CCNB1 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle 0.037756 0.797
1511 g2Pathway_h BioCarta H003048_01 Info Cell division cycle 25C H003048_01 M34065 (external link) 656 CDC25C (external link) How Progesterone Initiates the Oocyte Maturation, Regulation of cell cycle progression by Plk3, cell_cycle, cell_signaling 0.1856754 1.116
1512 g2Pathway_h BioCarta H007143_01 Info Hypothetical protein FLJ10883 H007143_01 AB028973 (external link) 184628 FLJ10883 (external link) cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage 0.2391265 0.908
1513 g2Pathway_h BioCarta H008573_01 Info Myelin transcription factor 1 H008573_01 M96980 (external link) 279562 MYT1 (external link) cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, How Progesterone Initiates the Oocyte Maturation, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage 0.3193113 1.107
1514 g2Pathway_h BioCarta H003351_01 Info Protein kinase, DNA-activated, catalytic polypeptide H003351_01 U47077 (external link) 155637 PRKDC (external link) Cell Cycle: G2/M Checkpoint, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system, DNA_damage, immunology 0.3847336 0.919
1515 g2Pathway_h BioCarta H002782_01 Info Wee1+ (S. pombe) homolog H002782_01 X62048 (external link) 75188 WEE1 (external link) cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology 0.4033875 1.142
1516 g2Pathway_h BioCarta H003766_01 Info Mouse double minute 2, human homolog of; p53-binding protein H003766_01 M92424 (external link) 170027 MDM2 (external link) ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc 0.8018001 0.978
1517 g2Pathway_h BioCarta H002232_01 Info Cell division cycle 34 H002232_01 L22005 (external link) 76932 CDC34 (external link) Cell Cycle: G2/M Checkpoint, Cyclin E Destruction Pathway, E2F1 Destruction Pathway, Ubiquitin mediated proteolysis 0.8799021 0.983
1518 g2Pathway_h BioCarta H003151_01 Info E1A binding protein p300 H003151_01 U01877 (external link) 25272 EP300 (external link) Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
1519 gabaPathway_h BioCarta H007996_01 Info GABA(A) receptor-associated protein H007996_01 NM_007278 (external link) 7719 GABARAP (external link) Gamma-aminobutyric Acid Receptor Life Cycle 0.0021636 1.497
1520 gabaPathway_h BioCarta H001660_01 Info Dynamin 1 H001660_01 L07807 (external link) 166161 DNM1 (external link) Endocytotic role of NDK, Phosphins and Dynamin, Gamma-aminobutyric Acid Receptor Life Cycle, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, �-arrestins in GPCR Desensitization 0.0631163 0.822
1521 gabaPathway_h BioCarta H001124_01 Info Gamma-aminobutyric acid (GABA) A receptor, alpha 1 H001124_01 NM_000806 (external link) 45740 GABRA1 (external link) 0.4106398 0.915
1522 gabaPathway_h BioCarta H005952_01 Info Gephyrin H005952_01 AB037806 (external link) 13405 GPHN (external link) Gamma-aminobutyric Acid Receptor Life Cycle 0.633937 0.932
1523 gabaPathway_h BioCarta H002383_01 Info Gamma-aminobutyric acid (GABA) A receptor, alpha 3 H002383_01 S62908 (external link) 123024 GABRA3 (external link) Cardiac Protection Against ROS , Gamma-aminobutyric Acid Receptor Life Cycle 0.853131 0.98
1524 keratinocytePathway_h BioCarta H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 (external link) 77432 EGFR (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
1525 keratinocytePathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 (external link) 180533 MAP2K3 (external link) fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
1526 keratinocytePathway_h BioCarta H003232_01 Info Mitogen-activated protein kinase kinase kinase 14 H003232_01 Y10256 (external link) 47007 MAP3K14 (external link) CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.005309 0.755
1527 keratinocytePathway_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1528 keratinocytePathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1529 keratinocytePathway_h BioCarta H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1530 keratinocytePathway_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1531 keratinocytePathway_h BioCarta H003259_01 Info Sp1 transcription factor H003259_01 J03133 (external link) 2021 SP1 (external link) Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.0557417 0.814
1532 keratinocytePathway_h BioCarta H003107_01 Info Mitogen-activated protein kinase 13 H003107_01 AF004709 (external link) 178695 MAPK13 (external link) Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system 0.0717244 1.171
1533 keratinocytePathway_h BioCarta H002049_01 Info Death-associated protein 6 H002049_01 AB015051 (external link) 180224 DAXX (external link) FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis 0.0788021 1.159
1534 keratinocytePathway_h BioCarta H002906_01 Info Protein kinase C, eta H002906_01 M55284 (external link) 315366 PRKCH (external link) 0.0889748 0.857
1535 keratinocytePathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1536 keratinocytePathway_h BioCarta H002506_01 Info Tumor necrosis factor receptor superfamily, member 1B H002506_01 M32315 (external link) 256278 TNFRSF1B (external link) TNFR2 Signaling Pathway, immunology 0.1166754 1.17
1537 keratinocytePathway_h BioCarta H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1538 keratinocytePathway_h BioCarta H002238_01 Info Protein kinase C, delta H002238_01 D10495 (external link) 155342 PRKCD (external link) HIV-I Nef: negative effector of Fas and TNF 0.1330434 1.177
1539 keratinocytePathway_h BioCarta H003249_01 Info V-ets avian erythroblastosis virus E26 oncogene homolog 1 H003249_01 X14798 (external link) 248109 ETS1 (external link) Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc 0.1428371 0.878
1540 keratinocytePathway_h BioCarta H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 (external link) 110299 MAP2K7 (external link) Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
1541 keratinocytePathway_h BioCarta H003644_01 Info Tumor necrosis factor receptor superfamily, member 6 H003644_01 X63717 (external link) 82359 TNFRSF6 (external link) apoptosis, immunology 0.4621499 0.927
1542 keratinocytePathway_h BioCarta H002340_01 Info Mitogen-activated protein kinase kinase kinase 5 H002340_01 U67156 (external link) 151988 MAP3K5 (external link) HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response 0.5393151 1.07
1543 keratinocytePathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1544 keratinocytePathway_h BioCarta H001681_01 Info Protein kinase C, theta H001681_01 L01087 (external link) 211593 PRKCQ (external link) Keratinocyte Differentiation, cell_cycle, cell_signaling, immunology, signal_transduction 0.8037373 1.019
1545 keratinocytePathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1546 keratinocytePathway_h BioCarta H001596_01 Info Protein kinase C, gamma H001596_01 Z15114 (external link) 2890 PRKCG (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.8498034 1.018
1547 keratinocytePathway_h BioCarta H001376_01 Info Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) H001376_01 AL133012 (external link) 306440 Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction 0.8639394 0.98
1548 keratinocytePathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1549 keratinocytePathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1550 lairPathway_h BioCarta H003139_01 Info Integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 H003139_01 M15395 (external link) 83968 ITGB2 (external link) Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis 0.0091308 1.578
1551 lairPathway_h BioCarta H002944_01 Info Interleukin 8 H002944_01 M17017 (external link) 624 IL8 (external link) Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology 0.0100881 0.681
1552 lairPathway_h BioCarta H002233_01 Info Selectin P ligand H002233_01 NM_003006 (external link) 79283 SELPLG (external link) Adhesion and Diapedesis of Granulocytes, Cells and Molecules involved in local acute inflammatory response, angiogenesis, immunology, metastasis 0.0126025 1.69
1553 lairPathway_h BioCarta H002526_01 Info Complement component 5 H002526_01 M57729 (external link) 1281 C5 (external link) Adhesion and Diapedesis of Granulocytes, Alternative Complement Pathway, Cells and Molecules involved in local acute inflammatory response, Classical Complement Pathway, Complement Pathway, Lectin Induced Complement Pathway, immunology, misc 0.245454 0.865
1554 lairPathway_h BioCarta H003794_01 Info Selectin P (granule membrane protein 140kD, antigen CD62) H003794_01 NM_003005 (external link) 73800 SELP (external link) Adhesion and Diapedesis of Granulocytes, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Monocyte and its Surface Molecules, cell_signaling, immunology, metastasis 0.3754462 1.081
1555 lairPathway_h BioCarta H003784_01 Info Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor H003784_01 M24283 (external link) 168383 ICAM1 (external link) Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis 0.4642919 0.93
1556 lairPathway_h BioCarta H002469_01 Info Complement component 3 H002469_01 K02765 (external link) 284394 C3 (external link) Alternative Complement Pathway, Cells and Molecules involved in local acute inflammatory response, Classical Complement Pathway, Complement Pathway, Lectin Induced Complement Pathway, immunology 0.6788808 1.044
1557 lairPathway_h BioCarta H003110_01 Info Interleukin 6 (interferon, beta 2) H003110_01 X04430 (external link) 93913 IL6 (external link) Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology 0.680804 1.036
1558 lairPathway_h BioCarta H003724_01 Info integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) H003724_01 NM_002211 (external link) 202661 ITGB1 (external link) Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis 0.9378203 0.993
1559 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H004823_01 Info Aldolase C, fructose-bisphosphate H004823_01 AF054987 (external link) 155247 ALDOC (external link) Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway 0.001576 0.707
1560 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H003374_01 Info Aldolase A, fructose-bisphosphate H003374_01 M11560 (external link) 273415 ALDOA (external link) Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology 0.0300936 1.252
1561 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H005517_01 Info Transaldolase 1 H005517_01 NM_006755 (external link) 77290 TALDO1 (external link) Pentose phosphate pathway 0.097425 1.207
1562 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H001387_01 Info Phosphofructokinase, platelet H001387_01 D25328 (external link) 99910 PFKP (external link) Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.101431 0.866
1563 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H002248_01 Info Glucose-6-phosphate dehydrogenase H002248_01 X03674 (external link) 80206 G6PD (external link) Glutathione metabolism, Pentose phosphate pathway, immunology 0.1773825 0.891
1564 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H005470_01 Info Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial CDS H005470_01 AL162062 (external link) 198182 0.1944956 1.125
1565 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H001378_01 Info Phosphofructokinase, muscle H001378_01 U24183 (external link) 75160 PFKM (external link) Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.2927445 0.908
1566 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H000502_01 Info Phosphoribosyl pyrophosphate synthetase 1 H000502_01 D00860 (external link) 56 PRPS1 (external link) Histidine metabolism, Pentose phosphate pathway, Purine metabolism, gene_regulation, transcription 0.3045664 0.909
1567 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H001548_01 Info Phosphogluconate dehydrogenase H001548_01 U30255 (external link) 75888 PGD (external link) Pentose phosphate pathway, immunology 0.3414801 1.107
1568 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H003868_01 Info Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) H003868_01 AJ012590 (external link) 194728 H6PD (external link) Pentose phosphate pathway 0.4449595 0.923
1569 MAP00030_Pentose_phosphate_pathway_h GenMAPP (external link) H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 (external link) 155455 PFKL (external link) Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
1570 ANDROGEN_UP_GENES_h na H001845_01 Info Spermidine/spermine N1-acetyltransferase H001845_01 AL050290 (external link) 28491 SAT (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Arginine and proline metabolism 0.0010835 1.431
1571 ANDROGEN_UP_GENES_h na H010168_01 Info SEC24 (S. cerevisiae) related gene family, member D H010168_01 AB018298 (external link) 19822 SEC24D (external link) 0.0012977 0.668
1572 ANDROGEN_UP_GENES_h na H005263_01 Info Kruppel-like factor 4 (gut) H005263_01 U70663 (external link) 7934 KLF4 (external link) 0.0051337 1.303
1573 ANDROGEN_UP_GENES_h na H001207_01 Info Cell membrane glycoprotein, 110000M(r) (surface antigen) H001207_01 D64154 (external link) 90107 GP110 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.0054987 0.761
1574 ANDROGEN_UP_GENES_h na H003576_01 Info Protein tyrosine phosphatase, non-receptor type 21 H003576_01 X79510 (external link) 155693 PTPN21 (external link) 0.0156683 0.71
1575 ANDROGEN_UP_GENES_h na H002780_01 Info Actinin, alpha 1 H002780_01 M95178 (external link) 119000 ACTN1 (external link) 0.0181707 0.767
1576 ANDROGEN_UP_GENES_h na H003902_01 Info Seladin-1 H003902_01 D13643 (external link) 75616 KIAA0018 (external link) 0.0276493 1.192
1577 ANDROGEN_UP_GENES_h na H001749_01 Info Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) H001749_01 M14200 (external link) 78888 DBI (external link) 0.0383862 1.259
1578 ANDROGEN_UP_GENES_h na H003086_01 Info Lectin, mannose-binding, 1 H003086_01 X71661 (external link) 287912 LMAN1 (external link) immunology 0.0472878 1.215
1579 ANDROGEN_UP_GENES_h na H001028_01 Info Alpha-2-glycoprotein 1, zinc H001028_01 X59766 (external link) 71 AZGP1 (external link) immunology 0.0695461 0.839
1580 ANDROGEN_UP_GENES_h na H006601_01 Info V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog H006601_01 AF055376 (external link) 30250 MAF (external link) GATA3 participate in activating the Th2 cytokine genes expression, tsonc 0.079493 0.812
1581 ANDROGEN_UP_GENES_h na H000736_01 Info 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) H000736_01 X66435 (external link) 77910 HMGCS1 (external link) SREBP control of lipid synthesis, Butanoate metabolism, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation 0.0809163 0.84
1582 ANDROGEN_UP_GENES_h na H004099_01 Info Phosphatidic acid phosphatase type 2A H004099_01 AF014403 (external link) 41569 PPAP2A (external link) Glycerolipid metabolism, Glycerophospholipid metabolism, Glycosphingolipid metabolism 0.0934873 0.851
1583 ANDROGEN_UP_GENES_h na H001575_01 Info UDP-glucose dehydrogenase H001575_01 AF061016 (external link) 28309 UGDH (external link) Nucleotide sugars metabolism, Pentose and glucuronate interconversions, Starch and sucrose metabolism, immunology 0.1026426 0.854
1584 ANDROGEN_UP_GENES_h na H001158_01 Info UDP-Gal:beta GlcNAc beta 1,4- galactosyltransferase, polypeptide 1 H001158_01 D29805 (external link) 198248 B4GALT1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Galactose metabolism, Keratan sulfate biosynthesis, N-Glycan biosynthesis 0.1752304 1.141
1585 ANDROGEN_UP_GENES_h na H012626_01 Info Beta-2-microglobulin H012626_01 AB021288 (external link) 75415 B2M (external link) Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology 0.1923361 1.156
1586 ANDROGEN_UP_GENES_h na H005886_01 Info Tumor protein D52 H005886_01 U18914 (external link) 2384 TPD52 (external link) 0.2657411 0.9
1587 ANDROGEN_UP_GENES_h na H000256_01 Info IQ motif containing GTPase activating protein 2 H000256_01 U51903 (external link) 78993 IQGAP2 (external link) 0.2689376 0.912
1588 ANDROGEN_UP_GENES_h na H001535_01 Info Sorbitol dehydrogenase H001535_01 L29008 (external link) 878 SORD (external link) Fructose and mannose metabolism, metabolism 0.3484797 1.082
1589 ANDROGEN_UP_GENES_h na H000577_01 Info Keratin 19 H000577_01 Y00503 (external link) 182265 KRT19 (external link) 0.3887528 0.905
1590 ANDROGEN_UP_GENES_h na H006429_01 Info Spermine synthase H006429_01 AD001528 (external link) 89718 SMS (external link) Arginine and proline metabolism, beta-Alanine metabolism, Urea cycle and metabolism of amino groups 0.475118 1.081
1591 ANDROGEN_UP_GENES_h na H004814_01 Info N-myc downstream regulated H004814_01 D87953 (external link) 75789 NDRG1 (external link) 0.5742952 1.047
1592 ANDROGEN_UP_GENES_h na H009428_01 Info Stearoyl-CoA desaturase (delta-9-desaturase) H009428_01 AB032261 (external link) 119597 SCD (external link) 0.6120428 0.959
1593 ANDROGEN_UP_GENES_h na H004696_01 Info Calcium/calmodulin-dependent protein kinase kinase 2, beta H004696_01 AB018330 (external link) 108708 CAMKK2 (external link) Ca++/ Calmodulin-dependent Protein Kinase Activation, Phosphatidylinositol signaling system 0.6902672 0.947
1594 ANDROGEN_UP_GENES_h na H007232_01 Info Ankylosis, progressive (mouse) homolog H007232_01 AK001799 (external link) 168640 ANKH (external link) 0.7291801 1.03
1595 ANDROGEN_UP_GENES_h na H005249_01 Info Homo sapiens 10q21 mRNA sequence H005249_01 AF198444 (external link) 279024 Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation 0.761598 0.965
1596 ANDROGEN_UP_GENES_h na H004975_01 Info RNA binding motif protein 10 H004975_01 AL137421 (external link) 154583 RBM10 (external link) 0.7811927 0.971
1597 ANDROGEN_UP_GENES_h na H000721_01 Info Isopentenyl-diphosphate delta isomerase H000721_01 X17025 (external link) 76038 IDI1 (external link) Biosynthesis of steroids, Terpenoid biosynthesis 0.8096306 0.973
1598 ANDROGEN_UP_GENES_h na H002975_01 Info Leukemia inhibitory factor receptor H002975_01 NM_002310 (external link) 2798 LIFR (external link) immunology 0.8467409 1.028
1599 ANDROGEN_UP_GENES_h na H003522_01 Info Glutathione reductase H003522_01 AF228704 (external link) 121524 GSR (external link) Free Radical Induced Apoptosis, Glutamate metabolism, Glutathione metabolism, immunology, pharmacology 0.906259 1.012
1600 ANDROGEN_UP_GENES_h na H000269_01 Info LIM protein (similar to rat protein kinase C-binding enigma) H000269_01 AF061258 (external link) 154103 LIM (external link) 0.9813357 1.002
1601 ANDROGEN_UP_GENES_h na H000425_01 Info C-mer proto-oncogene tyrosine kinase H000425_01 U08023 (external link) 306178 MERTK (external link) 0.9915103 1.001
1602 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000732_01 Info Insulin receptor substrate 1 H000732_01 S62539 (external link) 96063 IRS1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology 0.0013348 0.643
1603 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1604 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1605 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 (external link) 149957 RPS6KA1 (external link) Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1606 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H001323_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide H001323_01 X56468 (external link) 74405 YWHAQ (external link) Cell Cycle: G2/M Checkpoint 0.0151437 0.755
1607 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 (external link) 86858 RPS6KB1 (external link) CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1608 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003410_01 Info Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) H003410_01 U26727 (external link) 1174 CDKN2A (external link) Cell Cycle: G1/S Check Point , CTCF: First Multivalent Nuclear Factor, Cyclins and Cell Cycle Regulation, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0245577 0.782
1609 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 (external link) 162808 PIK3CD (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1610 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000612_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 3 H000612_01 U08316 (external link) 173965 RPS6KA3 (external link) MAP Kinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system 0.0473043 0.79
1611 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1612 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H014573_01 Info Homo sapiens HSPC106 mRNA, partial CDS H014573_01 AF161369 (external link) 187763 How Progesterone Initiates the Oocyte Maturation 0.0559133 0.793
1613 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000521_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 2 H000521_01 X85106 (external link) 301664 RPS6KA2 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0604408 1.207
1614 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1615 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002508_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide H002508_01 M86400 (external link) 75103 YWHAZ (external link) 0.153375 1.146
1616 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H005908_01 Info Flotillin 2 H005908_01 M60922 (external link) 184488 FLOT2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.179195 1.18
1617 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H007271_01 Info KIAA0894 protein H007271_01 AB020701 (external link) 199117 KIAA0894 (external link) 0.3201299 0.917
1618 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1619 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 (external link) 78802 GSK3B (external link) ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1620 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H010532_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide H010532_01 U54778 (external link) 79474 YWHAE (external link) Lissencephaly gene (LIS1) in neuronal migration and development 0.3886293 1.083
1621 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H013009_01 Info Adenylyl cyclase-associated protein H013009_01 L12168 (external link) 104125 CAP (external link) 0.4133824 1.094
1622 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002745_01 Info Inositol polyphosphate phosphatase-like 1 H002745_01 Y14385 (external link) 75339 INPPL1 (external link) Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Inositol phosphate metabolism, Phosphatidylinositol signaling system, DNA_damage 0.5531012 1.065
1623 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H008369_01 Info Tax interaction protein 40 H008369_01 NM_016948 (external link) 112933 TAX40 (external link) 0.5577165 1.057
1624 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H004961_01 Info Flotillin 1 H004961_01 AF089750 (external link) 179986 FLOT1 (external link) 0.5740947 1.05
1625 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H010826_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide H010826_01 AB024334 (external link) 25001 YWHAG (external link) 0.6175419 1.047
1626 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H002173_01 Info Cell division cycle 42 (GTP-binding protein, 25kD) H002173_01 AL121735 (external link) 146409 CDC42 (external link) Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction 0.6486191 1.035
1627 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003698_01 Info Protein tyrosine phosphatase, non-receptor type 1 H003698_01 M31724 (external link) 155894 PTPN1 (external link) cell_cycle, cell_signaling 0.6633733 1.054
1628 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1629 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H003654_01 Info Coagulation factor II (thrombin) receptor-like 2 H003654_01 U92971 (external link) 194351 F2RL2 (external link) immunology 0.6746058 0.966
1630 SIG_InsulinReceptorPathwayInCardiacMyocytes_h Signalling Alliance H011166_01 Info Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide H011166_01 X57346 (external link) 279920 YWHAB (external link) 0.8206709 0.982
1631 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1632 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 (external link) 87773 PRKACB (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1633 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1634 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 (external link) 149957 RPS6KA1 (external link) Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1635 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1636 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H005657_01 Info Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma H005657_01 L07044 (external link) 250857 CAMK2G (external link) Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Regulation of PGC-1a, Stathmin and breast cancer resistance to antimicrotubule agents, Transcription factor CREB and its extracellular signals 0.0367532 1.297
1637 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1638 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H012917_01 Info Homo sapiens clone 25048 mRNA sequence H012917_01 AF131776 (external link) 321572 0.1524925 0.87
1639 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 (external link) 173737 RAC1 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
1640 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H001698_01 Info Protein kinase, cAMP-dependent, regulatory, type II, alpha H001698_01 X14968 (external link) 289075 PRKAR2A (external link) AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation 0.2569617 1.125
1641 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H000645_01 Info Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) H000645_01 M33336 (external link) 183037 PRKAR1A (external link) Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction 0.4305614 0.935
1642 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1643 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H006522_01 Info Neuroendocrine secretory protein 55 H006522_01 AF105253 (external link) 113368 NESP55 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Attenuation of GPCR Signaling, CCR3 signaling in Eosinophils, ChREBP regulation by carbohydrates and cAMP, Corticosteroids and cardioprotection, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, Erk1/Erk2 Mapk Signaling pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Phospholipase C-epsilon pathway, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Transcription factor CREB and its extracellular signals 0.7456375 1.036
1644 crebPathway_h CREB is a transcription factor that binds to cAMP-responsive elements (CREs) to activate transcription in response to extracellular signaling. H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 (external link) 79194 CREB1 (external link) Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
1645 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003352_01 Info Interleukin 1 receptor, type I H003352_01 M27492 (external link) 82112 IL1R1 (external link) NF-kB Signaling Pathway, Signal transduction through IL1R, immunology 0.000502 0.677
1646 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002486_01 Info Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) H002486_01 M90299 (external link) 1270 GCK (external link) Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology 0.0014569 1.288
1647 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H004176_01 Info Mitogen-activated protein kinase kinase kinase 11 H004176_01 L32976 (external link) 89449 MAP3K11 (external link) MAP Kinase Signaling Pathway 0.0101996 1.263
1648 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1649 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003008_01 Info Mitogen-activated protein kinase kinase kinase 4 H003008_01 AF002715 (external link) 32353 MAP3K4 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.0127738 0.707
1650 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H001992_01 Info Activating transcription factor 2 H001992_01 X15875 (external link) 198166 ATF2 (external link) ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer 0.0178377 0.749
1651 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 (external link) 1846 TP53 (external link) Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
1652 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002588_01 Info Mitogen-activated protein kinase 7 H002588_01 U29725 (external link) 3080 MAPK7 (external link) Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), MAP Kinase Signaling Pathway, Role of Erk5 in Neuronal Survival, Phosphatidylinositol signaling system 0.0614441 0.811
1653 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H008870_01 Info Sterile-alpha motif and leucine zipper containing kinase AZK H008870_01 AF251441 (external link) 115175 ZAK (external link) Phosphatidylinositol signaling system 0.1273337 1.204
1654 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1655 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H000029_01 Info Mitogen-activated protein kinase kinase kinase 3 H000029_01 U78876 (external link) 29282 MAP3K3 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.2027051 1.138
1656 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002632_01 Info GRB2-associated binding protein 1 H002632_01 U43885 (external link) 239706 GAB1 (external link) Signaling of Hepatocyte Growth Factor Receptor 0.3021702 1.095
1657 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 (external link) 110299 MAP2K7 (external link) Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
1658 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002559_01 Info Mitogen-activated protein kinase kinase kinase 12 H002559_01 U07358 (external link) 211601 MAP3K12 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.3172697 1.101
1659 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H008351_01 Info Dual specificity phosphatase 10 H008351_01 AB026436 (external link) 177534 DUSP10 (external link) 0.382916 0.922
1660 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H006851_01 Info TAK1-binding protein 2; KIAA0733 protein H006851_01 AL117407 (external link) 109727 KIAA0733 (external link) Toll-Like Receptor Pathway 0.4908732 1.066
1661 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002340_01 Info Mitogen-activated protein kinase kinase kinase 5 H002340_01 U67156 (external link) 151988 MAP3K5 (external link) HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response 0.5393151 1.07
1662 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002173_01 Info Cell division cycle 42 (GTP-binding protein, 25kD) H002173_01 AL121735 (external link) 146409 CDC42 (external link) Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction 0.6486191 1.035
1663 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1664 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H001386_01 Info Mitogen-activated protein kinase kinase kinase 10 H001386_01 X90846 (external link) 30223 MAP3K10 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.7007387 0.968
1665 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H002470_01 Info Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 H002470_01 L41067 (external link) 172674 NFATC3 (external link) immunology 0.7190859 0.97
1666 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H000479_01 Info Dual specificity phosphatase 8 H000479_01 U27193 (external link) 41688 DUSP8 (external link) Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.7214843 1.03
1667 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H001715_01 Info Dual specificity phosphatase 4 H001715_01 AL137704 (external link) 2359 DUSP4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling 0.9634643 1.004
1668 ST_JNK_MAPK_Pathway_h Signalling Transduction KE H014820_01 Info Mitogen-activated protein kinase 9 H014820_01 NM_002752 (external link) 246857 MAPK9 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.9883614 0.998
1669 radiation_sensitivity_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 (external link) 169476 GAPD (external link) 0.0001082 1.485
1670 radiation_sensitivity_h BioCarta H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 (external link) 77432 EGFR (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
1671 radiation_sensitivity_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
1672 radiation_sensitivity_h BioCarta H002681_01 Info Cyclin D3 H002681_01 M92287 (external link) 83173 CCND3 (external link) Cyclins and Cell Cycle Regulation, cell_cycle 0.0084801 1.28
1673 radiation_sensitivity_h BioCarta H002092_01 Info Ataxia telangiectasia and Rad3 related H002092_01 U49844 (external link) 77613 ATR (external link) Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology 0.0105491 0.753
1674 radiation_sensitivity_h BioCarta H003739_01 Info Cell division cycle 2, G1 to S and G2 to M H003739_01 X05360 (external link) 184572 CDC2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle 0.0222229 0.733
1675 radiation_sensitivity_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 (external link) 1846 TP53 (external link) Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
1676 radiation_sensitivity_h BioCarta H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
1677 radiation_sensitivity_h BioCarta H002473_01 Info Insulin-like growth factor 1 receptor H002473_01 NM_000875 (external link) 239176 IGF1R (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology 0.079692 1.158
1678 radiation_sensitivity_h BioCarta H002987_01 Info Cyclin B2 H002987_01 AK001404 (external link) 194698 CCNB2 (external link) Estrogen-responsive protein Efp controls cell cycle and breast tumors growth 0.0829851 0.84
1679 radiation_sensitivity_h BioCarta H002323_01 Info Cyclin E1 H002323_01 M74093 (external link) 9700 CCNE1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle 0.1107382 0.884
1680 radiation_sensitivity_h BioCarta H002760_01 Info RAD51 (S. cerevisiae) homolog (E coli RecA homolog) H002760_01 D14134 (external link) 23044 RAD51 (external link) ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication 0.1212274 1.154
1681 radiation_sensitivity_h BioCarta H003605_01 Info BCL2-associated X protein H003605_01 L22474 (external link) 159428 BAX (external link) Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.253339 0.907
1682 radiation_sensitivity_h BioCarta H003644_01 Info Tumor necrosis factor receptor superfamily, member 6 H003644_01 X63717 (external link) 82359 TNFRSF6 (external link) apoptosis, immunology 0.4621499 0.927
1683 radiation_sensitivity_h BioCarta H003538_01 Info Actin, beta H003538_01 NM_001101 (external link) 288061 ACTB (external link) Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes 0.6253266 0.956
1684 radiation_sensitivity_h BioCarta H003542_01 Info V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene H003542_01 M11730 (external link) 323910 ERBB2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc 0.7160857 1.031
1685 radiation_sensitivity_h BioCarta H006841_01 Info Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) H006841_01 AL049301 (external link) 278577 Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.7810094 0.98
1686 radiation_sensitivity_h BioCarta H003766_01 Info Mouse double minute 2, human homolog of; p53-binding protein H003766_01 M92424 (external link) 170027 MDM2 (external link) ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc 0.8018001 0.978
1687 radiation_sensitivity_h BioCarta H003816_01 Info Caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) H003816_01 M87507 (external link) 2490 CASP1 (external link) Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, IL 18 Signaling Pathway, apoptosis, immunology 0.9157209 1.011
1688 radiation_sensitivity_h BioCarta H003027_01 Info Cyclin D2 H003027_01 D13639 (external link) 75586 CCND2 (external link) Cyclins and Cell Cycle Regulation, cell_cycle 0.9682473 0.996
1689 mtorPathway_h BioCarta H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 (external link) 86858 RPS6KB1 (external link) CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1690 mtorPathway_h BioCarta H002633_01 Info FK506 binding protein 12-rapamycin associated protein 1 H002633_01 U88966 (external link) 250723 FRAP1 (external link) B Cell Survival Pathway, CTCF: First Multivalent Nuclear Factor, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Stat3 Signaling Pathway, immunology 0.0222345 1.277
1691 mtorPathway_h BioCarta H002145_01 Info FK506-binding protein 1A (12kD) H002145_01 M34539 (external link) 752 FKBP1A (external link) mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart) 0.0298997 1.239
1692 mtorPathway_h BioCarta H005703_01 Info Eukaryotic translation initiation factor 4 gamma, 3 H005703_01 AF012072 (external link) 25732 EIF4G3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.0342104 1.272
1693 mtorPathway_h BioCarta H012604_01 Info Human clone 23933 mRNA sequence H012604_01 U79273 (external link) 239483 Internal Ribosome entry pathway, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase 0.0546956 1.194
1694 mtorPathway_h BioCarta H013804_01 Info Eukaryotic translation initiation factor 4A, isoform 1 H013804_01 D13748 (external link) 129673 EIF4A1 (external link) Internal Ribosome entry pathway, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase 0.1156946 1.148
1695 mtorPathway_h BioCarta H007640_01 Info Eukaryotic translation initiation factor 4A, isoform 2 H007640_01 AL117412 (external link) 173912 EIF4A2 (external link) 0.1166617 0.881
1696 mtorPathway_h BioCarta H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 (external link) 154729 PDPK1 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1697 mtorPathway_h BioCarta H003743_01 Info Eukaryotic translation initiation factor 4 gamma, 2 H003743_01 U73824 (external link) 183684 EIF4G2 (external link) gene_regulation, immunology 0.4776424 0.941
1698 mtorPathway_h BioCarta H007698_01 Info Eukaryotic translation initiation factor 4E binding protein 1 H007698_01 L36055 (external link) 71819 EIF4EBP1 (external link) mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway 0.5191259 1.06
1699 mtorPathway_h BioCarta H013300_01 Info Pyruvate dehydrogenase kinase, isoenzyme 2 H013300_01 L42451 (external link) 92261 PDK2 (external link) mTOR Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, cell_cycle, cell_signaling, signal_transduction 0.5991595 0.949
1700 mtorPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1701 mtorPathway_h BioCarta H010093_01 Info Eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD) H010093_01 D50929 (external link) 198899 EIF3S10 (external link) 0.8934066 1.012
1702 mtorPathway_h BioCarta H012856_01 Info MAP kinase-interacting serine/threonine kinase 1 H012856_01 AB000409 (external link) 5591 MKNK1 (external link) Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system 0.9455231 0.992
1703 glycolysisPathway_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 (external link) 169476 GAPD (external link) 0.0001082 1.485
1704 glycolysisPathway_h BioCarta H001878_01 Info Enolase 1, (alpha) H001878_01 M14328 (external link) 254105 ENO1 (external link) Glycolysis Pathway, Glycolysis / Gluconeogenesis, Phenylalanine, tyrosine and tryptophan biosynthesis 0.0756084 1.187
1705 glycolysisPathway_h BioCarta H007138_01 Info Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi H007138_01 S81916 (external link) 169313 Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology 0.0923463 1.164
1706 glycolysisPathway_h BioCarta H001636_01 Info Phosphoglycerate mutase 1 (brain) H001636_01 J04173 (external link) 181013 PGAM1 (external link) Glycolysis Pathway, Glycolysis / Gluconeogenesis, misc 0.2631445 1.109
1707 glycolysisPathway_h BioCarta H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 (external link) 155455 PFKL (external link) Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
1708 shh_lisa_h Manually Curated H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
1709 shh_lisa_h Manually Curated H003415_01 Info Protein kinase, cAMP-dependent, catalytic, beta H003415_01 M34181 (external link) 87773 PRKACB (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0048904 0.647
1710 shh_lisa_h Manually Curated H003183_01 Info Cyclin-dependent kinase 8 H003183_01 X85753 (external link) 25283 CDK8 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0083884 0.714
1711 shh_lisa_h Manually Curated H000211_01 Info Glioma-associated oncogene homolog (zinc finger protein) H000211_01 X07384 (external link) 2693 GLI (external link) development, gene_regulation, transcription, tsonc 0.0229022 0.821
1712 shh_lisa_h Manually Curated H002371_01 Info Cyclin B1 H002371_01 M25753 (external link) 23960 CCNB1 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle 0.037756 0.797
1713 shh_lisa_h Manually Curated H001698_01 Info Protein kinase, cAMP-dependent, regulatory, type II, alpha H001698_01 X14968 (external link) 289075 PRKAR2A (external link) AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation 0.2569617 1.125
1714 shh_lisa_h Manually Curated H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 (external link) 78802 GSK3B (external link) ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1715 shh_lisa_h Manually Curated H002127_01 Info Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A H002127_01 D86550 (external link) 75842 DYRK1A (external link) Sonic Hedgehog (Shh) Pathway 0.4628734 0.926
1716 shh_lisa_h Manually Curated H002675_01 Info Patched (Drosophila) homolog H002675_01 U43148 (external link) 159526 PTCH (external link) Sonic Hedgehog (Shh) Pathway, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, angiogenesis, development, immunology, metastasis, tsonc 0.4755683 0.942
1717 shh_lisa_h Manually Curated H000557_01 Info Exportin 1 (CRM1, yeast, homolog) H000557_01 Y08614 (external link) 79090 XPO1 (external link) Regulation of Spermatogenesis by CREM, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, gene_regulation, transcription 0.5346168 0.946
1718 shh_lisa_h Manually Curated H002165_01 Info Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 H002165_01 Y13493 (external link) 173135 DYRK2 (external link) Phosphatidylinositol signaling system, signal_transduction 0.6071417 1.067
1719 shh_lisa_h Manually Curated H006274_01 Info Ras protein-specific guanine nucleotide-releasing factor 1 H006274_01 L26584 (external link) 169350 RASGRF1 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle 0.7256743 1.03
1720 shh_lisa_h Manually Curated H000610_01 Info Glioma pathogenesis-related protein H000610_01 U16307 (external link) 64639 RTVP1 (external link) 0.9468739 1.009
1721 ST_G_alpha_5_Pathway_h Signalling Transduction KE H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1722 ST_G_alpha_5_Pathway_h Signalling Transduction KE H000309_01 Info CAMP response element-binding protein CRE-BPa H000309_01 L05515 (external link) 149 H_GS165L15.1 (external link) 0.0078273 1.479
1723 ST_G_alpha_5_Pathway_h Signalling Transduction KE H001062_01 Info N-acylsphingosine amidohydrolase (acid ceramidase) H001062_01 U70063 (external link) 75811 ASAH (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … 0.0187984 1.357
1724 ST_G_alpha_5_Pathway_h Signalling Transduction KE H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 (external link) 622 BRAF (external link) MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
1725 ST_G_alpha_5_Pathway_h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 (external link) 69771 BF (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.3702495 1.093
1726 ST_G_alpha_5_Pathway_h Signalling Transduction KE H007842_01 Info Gastrin H007842_01 NM_000805 (external link) 2681 GAS (external link) immunology 0.6295543 1.041
1727 ST_G_alpha_5_Pathway_h Signalling Transduction KE H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 (external link) 79194 CREB1 (external link) Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
1728 ptdinsPathway_h BioCarta H003000_01 Info RAB5A, member RAS oncogene family H003000_01 M28215 (external link) 73957 RAB5A (external link) Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc 0.0003278 0.591
1729 ptdinsPathway_h BioCarta H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 (external link) 80887 LYN (external link) BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
1730 ptdinsPathway_h BioCarta H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 (external link) 86858 RPS6KB1 (external link) CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1731 ptdinsPathway_h BioCarta H001739_01 Info Adaptor-related protein complex 2, mu 1 subunit H001739_01 D63475 (external link) 152936 AP2M1 (external link) 0.0326931 0.787
1732 ptdinsPathway_h BioCarta H001590_01 Info Early endosome antigen 1, 162kD H001590_01 L40157 (external link) 2864 EEA1 (external link) Phosphoinositides and their downstream targets., The role of FYVE-finger proteins in vesicle transport 0.0683087 0.8
1733 ptdinsPathway_h BioCarta H001387_01 Info Phosphofructokinase, platelet H001387_01 D25328 (external link) 99910 PFKP (external link) Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.101431 0.866
1734 ptdinsPathway_h BioCarta H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 (external link) 173737 RAC1 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
1735 ptdinsPathway_h BioCarta H002457_01 Info Protein kinase C, zeta H002457_01 Z15108 (external link) 78793 PRKCZ (external link) Phosphoinositides and their downstream targets., Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2375152 0.898
1736 ptdinsPathway_h BioCarta H003870_01 Info Bruton agammaglobulinemia tyrosine kinase H003870_01 NM_000061 (external link) 159494 BTK (external link) BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction 0.251649 1.148
1737 ptdinsPathway_h BioCarta H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 (external link) 154729 PDPK1 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1738 ptdinsPathway_h BioCarta H001378_01 Info Phosphofructokinase, muscle H001378_01 U24183 (external link) 75160 PFKM (external link) Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.2927445 0.908
1739 ptdinsPathway_h BioCarta H001586_01 Info ADP-ribosylation factor 1 H001586_01 AK000620 (external link) 74571 ARF1 (external link) ADP-Ribosylation Factor, Phosphoinositides and their downstream targets. 0.3260826 1.087
1740 ptdinsPathway_h BioCarta H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 (external link) 78802 GSK3B (external link) ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1741 ptdinsPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1742 ptdinsPathway_h BioCarta H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 (external link) 76366 BAD (external link) AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
1743 ptdinsPathway_h BioCarta H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 (external link) 155455 PFKL (external link) Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
1744 insulin_signaling_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 (external link) 169476 GAPD (external link) 0.0001082 1.485
1745 insulin_signaling_h BioCarta H000732_01 Info Insulin receptor substrate 1 H000732_01 S62539 (external link) 96063 IRS1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology 0.0013348 0.643
1746 insulin_signaling_h BioCarta H002486_01 Info Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) H002486_01 M90299 (external link) 1270 GCK (external link) Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology 0.0014569 1.288
1747 insulin_signaling_h BioCarta H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1748 insulin_signaling_h BioCarta H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1749 insulin_signaling_h BioCarta H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 (external link) 149957 RPS6KA1 (external link) Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
1750 insulin_signaling_h BioCarta H003305_01 Info Ribosomal protein S6 kinase, 70kD, polypeptide 1 H003305_01 M60724 (external link) 86858 RPS6KB1 (external link) CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0214523 1.448
1751 insulin_signaling_h BioCarta H002633_01 Info FK506 binding protein 12-rapamycin associated protein 1 H002633_01 U88966 (external link) 250723 FRAP1 (external link) B Cell Survival Pathway, CTCF: First Multivalent Nuclear Factor, mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Stat3 Signaling Pathway, immunology 0.0222345 1.277
1752 insulin_signaling_h BioCarta H006288_01 Info AE-binding protein 1 H006288_01 AF053944 (external link) 118397 AEBP1 (external link) 0.0298793 0.787
1753 insulin_signaling_h BioCarta H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1754 insulin_signaling_h BioCarta H002997_01 Info Vascular endothelial growth factor H002997_01 AF022375 (external link) 73793 VEGF (external link) Actions of Nitric Oxide in the Heart, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, misc 0.0306231 0.782
1755 insulin_signaling_h BioCarta H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1756 insulin_signaling_h BioCarta H014573_01 Info Homo sapiens HSPC106 mRNA, partial CDS H014573_01 AF161369 (external link) 187763 How Progesterone Initiates the Oocyte Maturation 0.0559133 0.793
1757 insulin_signaling_h BioCarta H007864_01 Info Solute carrier family 27 (fatty acid transporter), member 4 H007864_01 AF055899 (external link) 248953 SLC27A4 (external link) 0.07271 0.822
1758 insulin_signaling_h BioCarta H001676_01 Info Protein kinase C, iota H001676_01 L33881 (external link) 1904 PRKCI (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0761126 0.777
1759 insulin_signaling_h BioCarta H010696_01 Info NCK adaptor protein 2 H010696_01 AF047487 (external link) 101695 NCK2 (external link) 0.1245534 1.19
1760 insulin_signaling_h BioCarta H014546_01 Info Peptidylprolyl isomerase A (cyclophilin A) H014546_01 NM_021130 (external link) 182937 PPIA (external link) IL-2 Receptor Beta Chain in T cell Activation 0.129858 1.176
1761 insulin_signaling_h BioCarta H006546_01 Info Neuronal Shc H006546_01 D84361 (external link) 151123 SHC3 (external link) 0.1304854 1.158
1762 insulin_signaling_h BioCarta H001682_01 Info Oncogene TC21 H001682_01 M31468 (external link) 206097 TC21 (external link) 0.1382996 1.119
1763 insulin_signaling_h BioCarta H002248_01 Info Glucose-6-phosphate dehydrogenase H002248_01 X03674 (external link) 80206 G6PD (external link) Glutathione metabolism, Pentose phosphate pathway, immunology 0.1773825 0.891
1764 insulin_signaling_h BioCarta H005943_01 Info Docking protein 1, 62kD (downstream of tyrosine kinase 1) H005943_01 AF035299 (external link) 103854 DOK1 (external link) 0.179807 1.125
1765 insulin_signaling_h BioCarta H003783_01 Info Sterol regulatory element binding transcription factor 1 H003783_01 U00968 (external link) 166 SREBF1 (external link) SREBP control of lipid synthesis 0.2210756 0.895
1766 insulin_signaling_h BioCarta H002750_01 Info Neuropeptide Y H002750_01 K01911 (external link) 1832 NPY (external link) 0.2221305 1.126
1767 insulin_signaling_h BioCarta H000420_01 Info Eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD) H000420_01 X95648 (external link) 78592 EIF2B1 (external link) gene_regulation 0.2277796 0.855
1768 insulin_signaling_h BioCarta H003042_01 Info BCL2-like 1 H003042_01 Z23115 (external link) 305890 BCL2L1 (external link) Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology 0.2336065 1.143
1769 insulin_signaling_h BioCarta H002457_01 Info Protein kinase C, zeta H002457_01 Z15108 (external link) 78793 PRKCZ (external link) Phosphoinositides and their downstream targets., Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2375152 0.898
1770 insulin_signaling_h BioCarta H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 (external link) 622 BRAF (external link) MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
1771 insulin_signaling_h BioCarta H003286_01 Info 3-phosphoinositide dependent protein kinase-1 H003286_01 AF017995 (external link) 154729 PDPK1 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.2543058 1.119
1772 insulin_signaling_h BioCarta H002947_01 Info Protein phosphatase 1, catalytic subunit, alpha isoform H002947_01 S57501 (external link) 183994 PPP1CA (external link) cell_cycle, cell_signaling 0.2817559 1.112
1773 insulin_signaling_h BioCarta H006615_01 Info Acetyl-Coenzyme A carboxylase beta H006615_01 U89344 (external link) 183857 ACACB (external link) Fatty acid biosynthesis (path 1), Propanoate metabolism, Pyruvate metabolism 0.2905076 1.107
1774 insulin_signaling_h BioCarta H002652_01 Info Uncoupling protein 2 (mitochondrial, proton carrier) H002652_01 U94592 (external link) 80658 UCP2 (external link) immunology, misc 0.2962436 1.12
1775 insulin_signaling_h BioCarta H002632_01 Info GRB2-associated binding protein 1 H002632_01 U43885 (external link) 239706 GAB1 (external link) Signaling of Hepatocyte Growth Factor Receptor 0.3021702 1.095
1776 insulin_signaling_h BioCarta H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 (external link) 72241 MAP2K2 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
1777 insulin_signaling_h BioCarta H007271_01 Info KIAA0894 protein H007271_01 AB020701 (external link) 199117 KIAA0894 (external link) 0.3201299 0.917
1778 insulin_signaling_h BioCarta H001136_01 Info Glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) H001136_01 U01120 (external link) 242 G6PC (external link) Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism 0.3211576 0.901
1779 insulin_signaling_h BioCarta H002553_01 Info Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), H002553_01 M14083 (external link) 82085 SERPINE1 (external link) Fibrinolysis Pathway, Platelet Amyloid Precursor Protein Pathway 0.3225313 0.914
1780 insulin_signaling_h BioCarta H003068_01 Info Pyruvate kinase, muscle H003068_01 M26252 (external link) 198281 PKM2 (external link) Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism 0.3246109 1.102
1781 insulin_signaling_h BioCarta H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1782 insulin_signaling_h BioCarta H000650_01 Info Glycogen synthase kinase 3 beta H000650_01 L33801 (external link) 78802 GSK3B (external link) ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system 0.353328 1.118
1783 insulin_signaling_h BioCarta H002509_01 Info D component of complement (adipsin) H002509_01 M84526 (external link) 155597 DF (external link) immunology 0.3850381 0.93
1784 insulin_signaling_h BioCarta H013009_01 Info Adenylyl cyclase-associated protein H013009_01 L12168 (external link) 104125 CAP (external link) 0.4133824 1.094
1785 insulin_signaling_h BioCarta H003579_01 Info TGFB inducible early growth response H003579_01 S81439 (external link) 82173 TIEG (external link) angiogenesis, cell_cycle, cell_signaling, immunology, misc 0.431719 1.086
1786 insulin_signaling_h BioCarta H002624_01 Info Insulin receptor H002624_01 X02160 (external link) 89695 INSR (external link) Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology 0.433218 0.919
1787 insulin_signaling_h BioCarta H002698_01 Info Adrenergic, beta-3-, receptor H002698_01 NM_000025 (external link) 2549 ADRB3 (external link) behavior, immunology 0.4399337 0.93
1788 insulin_signaling_h BioCarta H002085_01 Info Orosomucoid 1 H002085_01 X02544 (external link) 572 ORM1 (external link) immunology 0.476851 1.07
1789 insulin_signaling_h BioCarta H002039_01 Info Phosphoenolpyruvate carboxykinase 2 (mitochondrial) H002039_01 X92720 (external link) 75812 PCK2 (external link) Citrate cycle (TCA cycle), Pyruvate metabolism 0.4857451 0.932
1790 insulin_signaling_h BioCarta H007698_01 Info Eukaryotic translation initiation factor 4E binding protein 1 H007698_01 L36055 (external link) 71819 EIF4EBP1 (external link) mTOR Signaling Pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway 0.5191259 1.06
1791 insulin_signaling_h BioCarta H001952_01 Info Ribosomal protein L13a H001952_01 X56932 (external link) 119122 RPL13A (external link) 0.565051 1.059
1792 insulin_signaling_h BioCarta H003538_01 Info Actin, beta H003538_01 NM_001101 (external link) 288061 ACTB (external link) Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes 0.6253266 0.956
1793 insulin_signaling_h BioCarta H003698_01 Info Protein tyrosine phosphatase, non-receptor type 1 H003698_01 M31724 (external link) 155894 PTPN1 (external link) cell_cycle, cell_signaling 0.6633733 1.054
1794 insulin_signaling_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1795 insulin_signaling_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1796 insulin_signaling_h BioCarta H001045_01 Info Thyroglobulin H001045_01 X05615 (external link) 305916 TG (external link) immunology 0.7668664 0.97
1797 insulin_signaling_h BioCarta H000245_01 Info Peroxisome proliferative activated receptor, gamma H000245_01 L40904 (external link) 100724 PPARG (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome 0.7837641 0.944
1798 insulin_signaling_h BioCarta H003015_01 Info Excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes over H003015_01 M13194 (external link) 59544 ERCC1 (external link) DNA_damage, DNA_replication, immunology 0.8177868 1.024
1799 insulin_signaling_h BioCarta H001596_01 Info Protein kinase C, gamma H001596_01 Z15114 (external link) 2890 PRKCG (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.8498034 1.018
1800 insulin_signaling_h BioCarta H012856_01 Info MAP kinase-interacting serine/threonine kinase 1 H012856_01 AB000409 (external link) 5591 MKNK1 (external link) Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system 0.9455231 0.992
1801 insulin_signaling_h BioCarta H015889_01 Info BCL2-like 1 H015889_01 NM_001191 (external link) 305890 BCL2L1 (external link) Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology 0.996743 1.001
1802 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1803 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1804 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H003006_01 Info Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 H003006_01 K02215 (external link) 3697 SERPINA8 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology 0.0063778 1.296
1805 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
1806 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002573_01 Info Protein tyrosine kinase 2 beta H002573_01 U43522 (external link) 20313 PTK2B (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction 0.0091935 1.367
1807 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
1808 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H005657_01 Info Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma H005657_01 L07044 (external link) 250857 CAMK2G (external link) Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Regulation of PGC-1a, Stathmin and breast cancer resistance to antimicrotubule agents, Transcription factor CREB and its extracellular signals 0.0367532 1.297
1809 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1810 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1811 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H012917_01 Info Homo sapiens clone 25048 mRNA sequence H012917_01 AF131776 (external link) 321572 0.1524925 0.87
1812 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H001649_01 Info Microtubule-associated protein tau H001649_01 NM_016835 (external link) 101174 MAPT (external link) Bioactive Peptide Induced Signaling Pathway, Deregulation of CDK5 in Alzheimer’s Disease 0.2534636 1.111
1813 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H000614_01 Info Guanine nucleotide binding protein (G protein), alpha 11 (Gq class) H000614_01 M69013 (external link) 1686 GNA11 (external link) 0.3060018 0.9
1814 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 (external link) 72241 MAP2K2 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
1815 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002329_01 Info Cyclin-dependent kinase 5 H002329_01 L04658 (external link) 166071 CDK5 (external link) cell_cycle, cell_signaling, signal_transduction 0.3594933 0.914
1816 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H011599_01 Info Homo sapiens mRNA; cDNA DKFZp434J194 (from clone DKFZp434J194) H011599_01 AL110227 (external link) 323067 0.661501 0.954
1817 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H000460_01 Info Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 H000460_01 AL049933 (external link) 203862 GNAI1 (external link) Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Bioactive Peptide Induced Signaling Pathway, CXCR4 Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Phospholipids as signaling intermediaries, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, cell_signaling, signal_transduction 0.7235673 1.046
1818 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1819 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H002404_01 Info Synaptotagmin I H002404_01 M55047 (external link) 154679 SYT1 (external link) 0.8170962 0.971
1820 biopeptidesPathway_h Extracellular signaling peptides exert biological effects via G-protein coupled receptors (GPCRs), which activate intracellular GTPases. H000579_01 Info Calmodulin 2 (phosphorylase kinase, delta) H000579_01 D45887 (external link) 182278 CALM2 (external link) 0.9689776 1.004
1821 ST_Ga13_Pathway_h Signalling Transduction KE H002186_01 Info Serum response factor (c-fos serum response element-binding transcription factor) H002186_01 J03161 (external link) 155321 SRF (external link) EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription 0.0017465 0.722
1822 ST_Ga13_Pathway_h Signalling Transduction KE H001360_01 Info Rho-associated, coiled-coil containing protein kinase 2 H001360_01 NM_004850 (external link) 58617 ROCK2 (external link) CCR3 signaling in Eosinophils, Phosphatidylinositol signaling system 0.0029412 0.776
1823 ST_Ga13_Pathway_h Signalling Transduction KE H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1824 ST_Ga13_Pathway_h Signalling Transduction KE H002188_01 Info Lipoprotein, Lp(a) H002188_01 X06290 (external link) 119520 LPA (external link) immunology 0.0147871 0.763
1825 ST_Ga13_Pathway_h Signalling Transduction KE H006644_01 Info Phosphorylase kinase, alpha 2 (liver) H006644_01 X80497 (external link) 54941 PHKA2 (external link) cell_cycle, cell_signaling, signal_transduction 0.0321533 1.233
1826 ST_Ga13_Pathway_h Signalling Transduction KE H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1827 ST_Ga13_Pathway_h Signalling Transduction KE H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1828 ST_Ga13_Pathway_h Signalling Transduction KE H003550_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) H003550_01 S76638 (external link) 73090 NFKB2 (external link) gene_regulation, immunology, transcription, tsonc 0.1593331 1.165
1829 ST_Ga13_Pathway_h Signalling Transduction KE H003747_01 Info Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 H003747_01 L19684 (external link) 159628 SERPINA4 (external link) 0.2081201 0.866
1830 ST_Ga13_Pathway_h Signalling Transduction KE H002112_01 Info PTK2 protein tyrosine kinase 2 H002112_01 L13616 (external link) 740 PTK2 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction 0.2346929 0.896
1831 ST_Ga13_Pathway_h Signalling Transduction KE H007827_01 Info Rho guanine exchange factor (GEF) 11 H007827_01 AB002378 (external link) 47822 ARHGEF11 (external link) Rho cell motility signaling pathway 0.2493266 1.109
1832 ST_Ga13_Pathway_h Signalling Transduction KE H000042_01 Info Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma H000042_01 AF074382 (external link) 43505 IKBKG (external link) CD40L Signaling Pathway, NF-kB Signaling Pathway, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway 0.2784213 1.13
1833 ST_Ga13_Pathway_h Signalling Transduction KE H000220_01 Info Guanine nucleotide binding protein (G protein), alpha 13 H000220_01 L22075 (external link) 1666 GNA13 (external link) PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Thrombin signaling and protease-activated receptors 0.2922764 1.182
1834 ST_Ga13_Pathway_h Signalling Transduction KE H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
1835 ST_Ga13_Pathway_h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 (external link) 69771 BF (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.3702495 1.093
1836 ST_Ga13_Pathway_h Signalling Transduction KE H005813_01 Info Phospholipase D2 H005813_01 AF038440 (external link) 104519 PLD2 (external link) Metabolism of Anandamide, an Endogenous Cannabinoid, Glycerophospholipid metabolism 0.4846144 1.066
1837 ST_Ga13_Pathway_h Signalling Transduction KE H008413_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 H008413_01 X77909 (external link) 2764 NFKBIL1 (external link) 0.5281661 1.058
1838 ST_Ga13_Pathway_h Signalling Transduction KE H002340_01 Info Mitogen-activated protein kinase kinase kinase 5 H002340_01 U67156 (external link) 151988 MAP3K5 (external link) HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response 0.5393151 1.07
1839 ST_Ga13_Pathway_h Signalling Transduction KE H001914_01 Info Phospholipase D1, phosphatidylcholine-specific H001914_01 U38545 (external link) 82587 PLD1 (external link) Metabolism of Anandamide, an Endogenous Cannabinoid, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Glycerophospholipid metabolism 0.5637309 1.056
1840 ST_Ga13_Pathway_h Signalling Transduction KE H002198_01 Info Discs, large (Drosophila) homolog 4 H002198_01 U83192 (external link) 23731 DLG4 (external link) Nitric Oxide Signaling Pathway, Synaptic Proteins at the Synaptic Junction 0.5763482 1.072
1841 ST_Ga13_Pathway_h Signalling Transduction KE H011529_01 Info Similar to vaccinia virus HindIII K4L ORF H011529_01 U60644 (external link) 74573 HU-K4 (external link) Metabolism of Anandamide, an Endogenous Cannabinoid 0.5878171 1.054
1842 ST_Ga13_Pathway_h Signalling Transduction KE H002173_01 Info Cell division cycle 42 (GTP-binding protein, 25kD) H002173_01 AL121735 (external link) 146409 CDC42 (external link) Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction 0.6486191 1.035
1843 ST_Ga13_Pathway_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1844 ST_Ga13_Pathway_h Signalling Transduction KE H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
1845 ST_Ga13_Pathway_h Signalling Transduction KE H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1846 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001655_01 Info Grancalcin H001655_01 M81637 (external link) 79381 GCL (external link) 0.0047006 1.807
1847 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H002704_01 Info Integrin, alpha 9 H002704_01 D25303 (external link) 222 ITGA9 (external link) cell_signaling, metastasis 0.0133682 0.766
1848 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H004577_01 Info Vasodilator-stimulated phosphoprotein H004577_01 Z46389 (external link) 93183 VASP (external link) cell_signaling, immunology, signal_transduction 0.0236006 1.288
1849 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H013335_01 Info Homo sapiens clone 24923 mRNA sequence H013335_01 AF131859 (external link) 7037 0.0241253 1.215
1850 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 (external link) 162808 PIK3CD (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1851 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003628_01 Info Dystroglycan 1 (dystrophin-associated glycoprotein 1) H003628_01 L19711 (external link) 76111 DAG1 (external link) Agrin in Postsynaptic Differentiation, immunology 0.034627 0.774
1852 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H000446_01 Info Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) H000446_01 L07633 (external link) 75348 PSME1 (external link) cell_signaling 0.0443091 1.231
1853 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001620_01 Info Diacylglycerol kinase, alpha (80kD) H001620_01 X62535 (external link) 172690 DGKA (external link) Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0809489 1.164
1854 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1855 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H002287_01 Info P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) H002287_01 U24152 (external link) 62402 PAK1 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway 0.1104284 0.815
1856 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 (external link) 78877 ITPKB (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
1857 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 (external link) 2722 ITPKA (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
1858 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H016038_01 Info Pallid (mouse) homolog, pallidin H016038_01 BC004819 (external link) 317714 PA (external link) 0.3260679 1.082
1859 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003337_01 Info B-factor, properdin H003337_01 L15702 (external link) 69771 BF (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.3702495 1.093
1860 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H000897_01 Info Inositol 1,4,5-triphosphate receptor, type 2 H000897_01 D26350 (external link) 238272 ITPR2 (external link) 0.5011337 1.061
1861 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
1862 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1863 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H010993_01 Info Electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) H010993_01 J04058 (external link) 169919 ETFA (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.7904014 0.968
1864 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H013182_01 Info ARP2 (actin-related protein 2, yeast) homolog H013182_01 AF006082 (external link) 42915 ACTR2 (external link) 0.840062 0.978
1865 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H011434_01 Info ARP3 (actin-related protein 3, yeast) homolog H011434_01 NM_005721 (external link) 5321 ACTR3 (external link) 0.8741333 1.017
1866 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H012065_01 Info Ribosomal protein S4, X-linked H012065_01 M58458 (external link) 108124 RPS4X (external link) immunology 0.8900601 1.017
1867 ST_Dictyostelium_discoideum_cAMP_Chemotaxis_Pathway_h Signalling Transduction KE H007337_01 Info Inositol 1,4,5-triphosphate receptor, type 3 H007337_01 U01062 (external link) 77515 ITPR3 (external link) 0.8999809 0.984
1868 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002227_01 Info Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) H002227_01 NM_000419 (external link) 785 ITGA2B (external link) immunology 0.0006863 1.674
1869 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002931_01 Info Selectin L (lymphocyte adhesion molecule 1) H002931_01 M25280 (external link) 82848 SELL (external link) Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis 0.0013165 2.024
1870 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002552_01 Info Integrin beta 3 binding protein (beta3-endonexin) H002552_01 U37139 (external link) 82084 ITGB3BP (external link) 0.0013566 0.728
1871 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002398_01 Info CD22 antigen H002398_01 X59350 (external link) 171763 CD22 (external link) angiogenesis, immunology, metastasis 0.0039052 1.468
1872 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000396_01 Info Fasciculation and elongation protein zeta 1 (zygin I) H000396_01 U60060 (external link) 79226 FEZ1 (external link) 0.0041715 0.684
1873 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006226_01 Info Protein tyrosine phosphatase, non-receptor type substrate 1 H006226_01 AB023430 (external link) 156114 PTPNS1 (external link) 0.0082221 1.447
1874 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H004690_01 Info G protein-coupled receptor 56 H004690_01 AJ011001 (external link) 6527 GPR56 (external link) 0.0090947 0.782
1875 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003139_01 Info Integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 H003139_01 M15395 (external link) 83968 ITGB2 (external link) Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis 0.0091308 1.578
1876 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002573_01 Info Protein tyrosine kinase 2 beta H002573_01 U43522 (external link) 20313 PTK2B (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction 0.0091935 1.367
1877 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002944_01 Info Interleukin 8 H002944_01 M17017 (external link) 624 IL8 (external link) Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology 0.0100881 0.681
1878 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001984_01 Info Hyaluronan-binding protein 2 H001984_01 D49742 (external link) 241363 HABP2 (external link) 0.0120275 0.727
1879 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002233_01 Info Selectin P ligand H002233_01 NM_003006 (external link) 79283 SELPLG (external link) Adhesion and Diapedesis of Granulocytes, Cells and Molecules involved in local acute inflammatory response, angiogenesis, immunology, metastasis 0.0126025 1.69
1880 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002704_01 Info Integrin, alpha 9 H002704_01 D25303 (external link) 222 ITGA9 (external link) cell_signaling, metastasis 0.0133682 0.766
1881 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002955_01 Info Discoidin domain receptor family, member 1 H002955_01 NM_013994 (external link) 75562 DDR1 (external link) 0.0169265 0.724
1882 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002921_01 Info CD33 antigen (gp67) H002921_01 M23197 (external link) 83731 CD33 (external link) Dendritic cells in regulating TH1 and TH2 Development, angiogenesis, metastasis 0.0177347 1.324
1883 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003049_01 Info Integrin, alpha X (antigen CD11C (p150), alpha polypeptide) H003049_01 M81695 (external link) 51077 ITGAX (external link) Dendritic cells in regulating TH1 and TH2 Development, cell_signaling, immunology, metastasis 0.0199733 1.464
1884 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002134_01 Info Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (se H002134_01 U60800 (external link) 79089 SEMA4D (external link) 0.0210381 1.307
1885 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002661_01 Info Egf-like module containing, mucin-like, hormone receptor-like sequence 1 H002661_01 X81479 (external link) 2375 EMR1 (external link) 0.0264536 1.293
1886 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006288_01 Info AE-binding protein 1 H006288_01 AF053944 (external link) 118397 AEBP1 (external link) 0.0298793 0.787
1887 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000986_01 Info Glycoprotein IX (platelet) H000986_01 X52997 (external link) 1144 GP9 (external link) immunology 0.0311848 1.262
1888 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002243_01 Info Ras homolog gene family, member E H002243_01 S82240 (external link) 6838 ARHE (external link) immunology 0.032366 1.421
1889 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003546_01 Info Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) H003546_01 X06256 (external link) 149609 ITGA5 (external link) cell_signaling, immunology, metastasis 0.0363906 1.254
1890 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H013467_01 Info Claudin 10 H013467_01 U89916 (external link) 26126 CLDN10 (external link) 0.0518009 0.837
1891 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003719_01 Info Integrin, beta 7 H003719_01 M68892 (external link) 1741 ITGB7 (external link) cell_signaling, immunology, metastasis 0.0529984 0.815
1892 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001223_01 Info Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and sh H001223_01 U52840 (external link) 27621 SEMA5A (external link) 0.0591735 0.853
1893 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003051_01 Info Neural cell adhesion molecule 1 H003051_01 S71824 (external link) 167988 NCAM1 (external link) Synaptic Proteins at the Synaptic Junction, cell_signaling, immunology, metastasis 0.0668517 1.161
1894 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005433_01 Info Claudin 1 H005433_01 AF134160 (external link) 7327 CLDN1 (external link) 0.0719995 0.772
1895 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H012084_01 Info Contactin 6 H012084_01 AB003592 (external link) 109050 CNTN6 (external link) 0.0825203 1.155
1896 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001954_01 Info Milk fat globule-EGF factor 8 protein H001954_01 U58516 (external link) 3745 MFGE8 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.082982 0.826
1897 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H008629_01 Info Spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive) H008629_01 Y16610 (external link) 296847 SPG7 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.103499 1.154
1898 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003524_01 Info Vitronectin (serum spreading factor, somatomedin B, complement S-protein) H003524_01 X03168 (external link) 2257 VTN (external link) angiogenesis, immunology, misc 0.1100276 0.835
1899 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011697_01 Info Bystin-like H011697_01 L36720 (external link) 106880 BYSL (external link) 0.1129454 0.796
1900 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001908_01 Info Discoidin domain receptor family, member 2 H001908_01 X74764 (external link) 71891 DDR2 (external link) 0.1167676 0.839
1901 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H009546_01 Info Small EDRK-rich factor 2 H009546_01 NM_005770 (external link) 323806 SERF2 (external link) 0.120338 1.195
1902 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003899_01 Info Chemokine (C-C motif) receptor 1 H003899_01 D10925 (external link) 301921 CCR1 (external link) Selective expression of chemokine receptors during T-cell polarization, immunology 0.1258208 1.15
1903 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002937_01 Info Fibronectin 1 H002937_01 X02761 (external link) 287820 FN1 (external link) angiogenesis, cell_signaling, immunology, metastasis 0.128354 1.194
1904 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002990_01 Info Cadherin 8, type 2 H002990_01 AB035305 (external link) 79133 CDH8 (external link) 0.1344667 0.864
1905 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000087_01 Info Transforming growth factor beta 1 induced transcript 1 H000087_01 AB007836 (external link) 25511 TGFB1I1 (external link) 0.1561907 1.139
1906 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H015048_01 Info Protocadherin beta 3 H015048_01 NM_018937 (external link) 283086 PCDHB3 (external link) 0.1614222 0.865
1907 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H008391_01 Info Plakophilin 4 H008391_01 X81889 (external link) 152151 PKP4 (external link) 0.1673938 1.162
1908 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006236_01 Info Coagulation factor VIII, procoagulant component (hemophilia A) H006236_01 M90707 (external link) 79345 F8 (external link) Intrinsic Prothrombin Activation Pathway 0.1700597 0.828
1909 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002555_01 Info Junction plakoglobin H002555_01 Z68228 (external link) 2340 JUP (external link) immunology 0.1776342 0.877
1910 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005908_01 Info Flotillin 2 H005908_01 M60922 (external link) 184488 FLOT2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.179195 1.18
1911 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 (external link) 173737 RAC1 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
1912 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000520_01 Info Cell adhesion molecule with homology to L1CAM (close homologue of L1) H000520_01 AF002246 (external link) 210863 CHL1 (external link) 0.2072085 0.87
1913 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002477_01 Info Neogenin (chicken) homolog 1 H002477_01 U61262 (external link) 90408 NEO1 (external link) angiogenesis, metastasis 0.2084414 1.135
1914 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003818_01 Info Ectonucleoside triphosphate diphosphohydrolase 1 H003818_01 AJ133133 (external link) 205353 ENTPD1 (external link) Purine metabolism, Pyrimidine metabolism 0.2115941 1.145
1915 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001101_01 Info CD164 antigen, sialomucin H001101_01 D14043 (external link) 43910 CD164 (external link) 0.2123692 0.89
1916 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002456_01 Info Cadherin 4, type 1, R-cadherin (retinal) H002456_01 L34059 (external link) 89484 CDH4 (external link) cell_signaling, metastasis 0.213629 0.879
1917 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H010955_01 Info Peanut (Drosophila)-like 1 H010955_01 U74628 (external link) 3847 PNUTL1 (external link) immunology 0.2330497 1.154
1918 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001382_01 Info Calcium/calmodulin-dependent serine protein kinase (MAGUK family) H001382_01 AF035582 (external link) 151469 CASK (external link) Synaptic Proteins at the Synaptic Junction 0.2450624 0.894
1919 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011988_01 Info Mucosal vascular addressin cell adhesion molecule 1 H011988_01 U43628 (external link) 102598 MADCAM1 (external link) Adhesion and Diapedesis of Lymphocytes 0.2675057 1.096
1920 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002337_01 Info Stromal cell-derived factor 1 H002337_01 L36033 (external link) 237356 SDF1 (external link) CXCR4 Signaling Pathway, Pertussis toxin-insensitive CCR5 Signaling in Macrophage 0.2981205 1.118
1921 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H015755_01 Info Chemokine (C-C motif) receptor 1 H015755_01 NM_001295 (external link) 301921 CCR1 (external link) Selective expression of chemokine receptors during T-cell polarization, immunology 0.3366567 1.129
1922 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H008328_01 Info Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 H008328_01 AF233365 (external link) 154210 EDG1 (external link) Phospholipids as signaling intermediaries, immunology 0.3391872 0.905
1923 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005782_01 Info Retinoschisis (X-linked, juvenile) 1 H005782_01 AF014459 (external link) 113250 RS1 (external link) 0.3512019 1.069
1924 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002557_01 Info Protein tyrosine phosphatase, receptor type, U H002557_01 X97198 (external link) 19718 PTPRU (external link) 0.3521897 1.092
1925 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003699_01 Info Chondroitin sulfate proteoglycan 2 (versican) H003699_01 U16306 (external link) 81800 CSPG2 (external link) immunology 0.3780363 0.892
1926 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006685_01 Info Macrophage erythroblast attacher H006685_01 AK001088 (external link) 20815 MAEA (external link) 0.4159192 1.104
1927 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011069_01 Info Nephrosis 1, congenital, Finnish type (nephrin) H011069_01 AF035835 (external link) 190311 NPHS1 (external link) 0.4304362 1.087
1928 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002976_01 Info G protein-coupled receptor 9 H002976_01 X95876 (external link) 198252 GPR9 (external link) IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization 0.4390046 0.918
1929 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011423_01 Info C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 H011423_01 AJ133532 (external link) 115515 CLECSF6 (external link) 0.4493538 1.095
1930 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001943_01 Info CD58 antigen, (lymphocyte function-associated antigen 3) H001943_01 Y00636 (external link) 75626 CD58 (external link) IL 17 Signaling Pathway, cell_signaling, immunology, metastasis 0.4535251 0.932
1931 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002328_01 Info Integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage an H002328_01 J03925 (external link) 172631 ITGAM (external link) Adhesion and Diapedesis of Granulocytes, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis 0.4578639 0.936
1932 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001175_01 Info Lutheran blood group (Auberger b antigen included) H001175_01 X83425 (external link) 155048 LU (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, immunology 0.4765592 1.07
1933 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H004192_01 Info Homo sapiens mRNA; cDNA DKFZp566E103 (from clone DKFZp566E103) H004192_01 AL050053 (external link) 227397 Synaptic Proteins at the Synaptic Junction, cell_signaling, immunology, metastasis 0.4769586 0.93
1934 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H010984_01 Info Contactin associated protein 1 H010984_01 U87223 (external link) 31622 CNTNAP1 (external link) 0.4850281 0.941
1935 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002035_01 Info FAT tumor suppressor (Drosophila) homolog H002035_01 X87241 (external link) 166994 FAT (external link) cell_signaling, immunology, metastasis, tsonc 0.4989072 0.922
1936 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H010407_01 Info Adhesion glycoprotein H010407_01 U56102 (external link) 57699 DNAM-1 (external link) 0.5470565 0.946
1937 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003424_01 Info Chemokine (C-C motif) receptor 3 H003424_01 U28694 (external link) 158324 CCR3 (external link) CCR3 signaling in Eosinophils, IL 5 Signaling Pathway, Selective expression of chemokine receptors during T-cell polarization, The Role of Eosinophils in the Chemokine Network of Allergy, immunology 0.5671442 1.138
1938 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003454_01 Info Integrin, beta 6 H003454_01 M35198 (external link) 123125 ITGB6 (external link) immunology 0.6028747 1.064
1939 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001310_01 Info Natural killer cell transcript 4 H001310_01 M59807 (external link) 943 NK4 (external link) 0.6125553 1.066
1940 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H012881_01 Info Homo sapiens cDNA FLJ20843 fis, clone ADKA01954 H012881_01 AK000850 (external link) 272203 0.6176754 1.054
1941 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006635_01 Info Homo sapiens clone 23607 mRNA sequence H006635_01 AF038181 (external link) 167825 ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc 0.6181322 1.041
1942 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H013889_01 Info SEEK1 protein H013889_01 AB031479 (external link) 91600 SEEK1 (external link) 0.6212047 1.057
1943 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000279_01 Info Leupaxin H000279_01 AF062075 (external link) 49587 LPXN (external link) 0.6381623 1.046
1944 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002570_01 Info Interleukin 2 H002570_01 S82692 (external link) 89679 IL2 (external link) Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology 0.6483346 1.043
1945 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H000757_01 Info Calcium and integrin binding protein (DNA-dependent protein kinase interacting protein) H000757_01 U85611 (external link) 10803 SIP2-28 (external link) 0.6487041 0.959
1946 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001985_01 Info RAB13, member RAS oncogene family H001985_01 X75593 (external link) 151536 RAB13 (external link) tsonc 0.6547022 0.954
1947 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005759_01 Info Vinexin beta (SH3-containing adaptor molecule-1) H005759_01 AF037261 (external link) 33787 SCAM-1 (external link) 0.6677983 0.927
1948 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002380_01 Info Chemokine (C-C motif) receptor 8 H002380_01 D49919 (external link) 113222 CCR8 (external link) immunology 0.6915296 1.035
1949 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002212_01 Info Zyxin H002212_01 X95735 (external link) 75873 ZYX (external link) Integrin Signaling Pathway 0.7015822 1.041
1950 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002425_01 Info CD2 antigen (p50), sheep red blood cell receptor H002425_01 M16336 (external link) 89476 CD2 (external link) Dendritic cells in regulating TH1 and TH2 Development, IL 17 Signaling Pathway, NO2-dependent IL 12 Pathway in NK cells, Stathmin and breast cancer resistance to antimicrotubule agents, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, angiogenesis, immunology, metastasis 0.7161918 1.064
1951 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002317_01 Info Chemokine (C-X3-C) receptor 1 H002317_01 U20350 (external link) 78913 CX3CR1 (external link) immunology 0.7275779 1.038
1952 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H007610_01 Info Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 H007610_01 AB016898 (external link) 100469 MLLT4 (external link) misc 0.7354494 0.972
1953 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005451_01 Info Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) H005451_01 S70348 (external link) 87149 ITGB3 (external link) Phospholipids as signaling intermediaries, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis 0.7730219 1.027
1954 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002330_01 Info Cadherin 15, M-cadherin (myotubule) H002330_01 D83542 (external link) 148090 CDH15 (external link) 0.7996949 0.974
1955 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H006776_01 Info Tetraspan 1 H006776_01 AF065388 (external link) 38972 TSPAN-1 (external link) 0.819954 1.022
1956 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H003407_01 Info Von Willebrand factor H003407_01 X04385 (external link) 110802 VWF (external link) angiogenesis, immunology, misc 0.8290575 1.021
1957 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H009708_01 Info Cell recognition molecule Caspr2 H009708_01 NM_014141 (external link) 106552 KIAA0868 (external link) 0.8379152 1.017
1958 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H001286_01 Info Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4 H001286_01 AL161973 (external link) 100469 MLLT4 (external link) misc 0.8547896 1.027
1959 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002490_01 Info Hexabrachion (tenascin C, cytotactin) H002490_01 X78565 (external link) 289114 HXB (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.856155 0.983
1960 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H005864_01 Info Immunoglobulin superfamily, member 1 H005864_01 AB002362 (external link) 22111 IGSF1 (external link) 0.8881091 0.983
1961 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H002891_01 Info Small inducible cytokine A4 (homologous to mouse Mip-1b) H002891_01 J04130 (external link) 75703 SCYA4 (external link) Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization 0.8975649 1.014
1962 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H004275_01 Info Elastin microfibril interface located protein H004275_01 AL050138 (external link) 63348 EMILIN (external link) 0.8986492 1.013
1963 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H011503_01 Info Integrin, beta-like 1 (with EGF-like repeat domains) H011503_01 AF072752 (external link) 82582 ITGBL1 (external link) angiogenesis 0.9588704 0.995
1964 cell_adhesion_h The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. H009310_01 Info Immunoglobulin superfamily containing leucine-rich repeat H009310_01 AB024536 (external link) 102171 ISLR (external link) 0.9743631 0.997
1965 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1966 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H000877_01 Info Sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) H000877_01 X59960 (external link) 77813 SMPD1 (external link) Ceramide Signaling Pathway, Glycosphingolipid metabolism 0.0075987 1.354
1967 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
1968 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
1969 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002786_01 Info Caspase 8, apoptosis-related cysteine protease H002786_01 X98172 (external link) 19949 CASP8 (external link) Caspase Cascade in Apoptosis, Ceramide Signaling Pathway, D4-GDI Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, SODD/TNFR1 Signaling Pathway, TNFR1 Signaling Pathway, apoptosis, immunology 0.1208497 1.128
1970 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
1971 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003605_01 Info BCL2-associated X protein H003605_01 L22474 (external link) 159428 BAX (external link) Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.253339 0.907
1972 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H006662_01 Info Fas (TNFRSF6)-associated via death domain H006662_01 X84709 (external link) 86131 FADD (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , NF-kB Signaling Pathway, SODD/TNFR1 Signaling Pathway, TNFR1 Signaling Pathway, immunology 0.292449 1.108
1973 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002660_01 Info TNFRSF1A-associated via death domain H002660_01 L41690 (external link) 89862 TRADD (external link) Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , MAP Kinase Signaling Pathway, NF-kB Signaling Pathway, p38 MAPK Signaling Pathway , SODD/TNFR1 Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway 0.3157474 1.092
1974 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H000028_01 Info Programmed cell death 8 (apoptosis-inducing factor) H000028_01 AL049703 (external link) 18720 PDCD8 (external link) Ceramide Signaling Pathway, Opposing roles of AIF in Apoptosis and Cell Survival, Role of Mitochondria in Apoptotic Signaling 0.3727024 0.894
1975 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H000025_01 Info Neutral sphingomyelinase (N-SMase) activation associated factor H000025_01 X96586 (external link) 78687 NSMAF (external link) Ceramide Signaling Pathway 0.5133585 0.948
1976 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 (external link) 76366 BAD (external link) AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
1977 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
1978 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H006841_01 Info Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) H006841_01 AL049301 (external link) 278577 Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.7810094 0.98
1979 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
1980 ceramidePathway_h Ceramide is a lipid signaling molecule that can activate proliferative or apoptotic pathways, depending on signaling context, localization, and cell type. H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H00 2963_01L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
1981 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H003000_01 Info RAB5A, member RAS oncogene family H003000_01 M28215 (external link) 73957 RAB5A (external link) Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc 0.0003278 0.591
1982 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 (external link) 77432 EGFR (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
1983 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H001590_01 Info Early endosome antigen 1, 162kD H001590_01 L40157 (external link) 2864 EEA1 (external link) Phosphoinositides and their downstream targets., The role of FYVE-finger proteins in vesicle transport 0.0683087 0.8
1984 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H002682_01 Info Transferrin H002682_01 S95936 (external link) 284176 TF (external link) The role of FYVE-finger proteins in vesicle transport, immunology 0.5663067 0.93
1985 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H000655_01 Info Hepatocyte growth factor-regulated tyrosine kinase substrate H000655_01 U43895 (external link) 24756 HGS (external link) The role of FYVE-finger proteins in vesicle transport 0.7645593 1.024
1986 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H015257_01 Info Transferrin H015257_01 NM_001063 (external link) 284176 TF (external link) The role of FYVE-finger proteins in vesicle transport, immunology 0.860187 1.017
1987 eea1Pathway_h The FYVE-finger proteins EEA1 and HRS are localized to endosome membranes and regulate sorting and ubiquitination in the vesicle transport system. H002993_01 Info Transferrin receptor (p90, CD71) H002993_01 X01060 (external link) 77356 TFRC (external link) The role of FYVE-finger proteins in vesicle transport, immunology 0.9856571 1.002
1988 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
1989 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
1990 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 (external link) 80887 LYN (external link) BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
1991 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001348_01 Info Phosphoinositide-3-kinase, catalytic, delta polypeptide H001348_01 U86453 (external link) 162808 PIK3CD (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.0324563 1.426
1992 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003628_01 Info Dystroglycan 1 (dystrophin-associated glycoprotein 1) H003628_01 L19711 (external link) 76111 DAG1 (external link) Agrin in Postsynaptic Differentiation, immunology 0.034627 0.774
1993 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H016134_01 Info V-akt murine thymoma viral oncogene homolog 2 H016134_01 NM_001626 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.0530988 1.287
1994 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001591_01 Info Phospholipase C, gamma 2 (phosphatidylinositol-specific) H001591_01 M37238 (external link) 75648 PLCG2 (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1077771 1.239
1995 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 (external link) 78877 ITPKB (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
1996 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 (external link) 2722 ITPKA (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
1997 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003550_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) H003550_01 S76638 (external link) 73090 NFKB2 (external link) gene_regulation, immunology, transcription, tsonc 0.1593331 1.165
1998 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003747_01 Info Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 H003747_01 L19684 (external link) 159628 SERPINA4 (external link) 0.2081201 0.866
1999 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003870_01 Info Bruton agammaglobulinemia tyrosine kinase H003870_01 NM_000061 (external link) 159494 BTK (external link) BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction 0.251649 1.148
2000 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003441_01 Info Breakpoint cluster region H003441_01 X02596 (external link) 234799 BCR (external link) Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, immunology, tsonc 0.2521813 1.116
2001 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 (external link) 72241 MAP2K2 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
2002 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003497_01 Info V-akt murine thymoma viral oncogene homolog 2 H003497_01 M77198 (external link) 326445 AKT2 (external link) Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc 0.3314111 0.872
2003 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H008413_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 H008413_01 X77909 (external link) 2764 NFKBIL1 (external link) 0.5281661 1.058
2004 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
2005 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 (external link) 76366 BAD (external link) AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
2006 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2007 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003651_01 Info EphB2 H003651_01 AF025304 (external link) 125124 EPHB2 (external link) development 0.7855294 0.971
2008 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
2009 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H012662_01 Info Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954 H012662_01 AK001067 (external link) 6226 0.8484663 1.017
2010 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2011 ST_B_Cell_Antigen_Receptor_h Signalling Transduction KE H003340_01 Info C-src tyrosine kinase H003340_01 X60114 (external link) 77793 CSK (external link) Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Activation of Src by Protein-tyrosine phosphatase alpha, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, signal_transduction 0.9390319 1.008
2012 tidPathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2013 tidPathway_h BioCarta H002834_01 Info Interferon gamma receptor 2 (interferon gamma transducer 1) H002834_01 U05875 (external link) 177559 IFNGR2 (external link) Chaperones modulate interferon Signaling Pathway, IFN gamma signaling pathway , Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, immunology 0.0062495 1.401
2014 tidPathway_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 (external link) 1846 TP53 (external link) Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
2015 tidPathway_h BioCarta H002506_01 Info Tumor necrosis factor receptor superfamily, member 1B H002506_01 M32315 (external link) 256278 TNFRSF1B (external link) TNFR2 Signaling Pathway, immunology 0.1166754 1.17
2016 tidPathway_h BioCarta H006206_01 Info PDZ-73 protein H006206_01 AB006955 (external link) 132945 PDZ-73/NY-CO-38 (external link) 0.3146985 1.083
2017 tidPathway_h BioCarta H002447_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha H002447_01 M69043 (external link) 81328 NFKBIA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … 0.8245205 0.975
2018 tidPathway_h BioCarta H012648_01 Info DnaJ (Hsp40) homolog, subfamily A, member 3 H012648_01 AF061749 (external link) 311057 DNAJA3 (external link) Chaperones modulate interferon Signaling Pathway 0.8393634 0.984
2019 tidPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2020 tidPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
2021 DOWNREG_BY_HOXA9_h Manually Curated H003124_01 Info Fc fragment of IgG, receptor, transporter, alpha H003124_01 U12255 (external link) 111903 FCGRT (external link) 2.86e-05 1.917
2022 DOWNREG_BY_HOXA9_h Manually Curated H002406_01 Info Jun B proto-oncogene H002406_01 X51345 (external link) 198951 JUNB (external link) GATA3 participate in activating the Th2 cytokine genes expression, tsonc 0.0021761 1.408
2023 DOWNREG_BY_HOXA9_h Manually Curated H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 (external link) 80887 LYN (external link) BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
2024 DOWNREG_BY_HOXA9_h Manually Curated H000316_01 Info Delta sleep inducing peptide, immunoreactor H000316_01 AL110191 (external link) 75450 DSIPI (external link) 0.0102545 1.531
2025 DOWNREG_BY_HOXA9_h Manually Curated H006355_01 Info KIAA1451 protein H006355_01 AL049923 (external link) 109694 KIAA1451 (external link) 0.0105169 1.369
2026 DOWNREG_BY_HOXA9_h Manually Curated H000199_01 Info Translocated promoter region (to activated MET oncogene) H000199_01 X66397 (external link) 169750 TPR (external link) tsonc 0.036441 0.801
2027 DOWNREG_BY_HOXA9_h Manually Curated H001971_01 Info Retinoblastoma-binding protein 6 H001971_01 X85133 (external link) 85273 RBBP6 (external link) 0.0366619 0.747
2028 DOWNREG_BY_HOXA9_h Manually Curated H006255_01 Info Syndecan binding protein (syntenin) H006255_01 AF000652 (external link) 8180 SDCBP (external link) 0.0567867 1.234
2029 DOWNREG_BY_HOXA9_h Manually Curated H002168_01 Info GATA-binding protein 2 H002168_01 M68891 (external link) 760 GATA2 (external link) gene_regulation, misc, transcription 0.0841754 0.806
2030 DOWNREG_BY_HOXA9_h Manually Curated H004936_01 Info DKFZP564A122 protein H004936_01 AL110269 (external link) 187991 DKFZP564A122 (external link) 0.0852946 1.175
2031 DOWNREG_BY_HOXA9_h Manually Curated H007504_01 Info Hemoglobin, epsilon 1 H007504_01 NM_005330 (external link) 117848 HBE1 (external link) 0.118007 0.749
2032 DOWNREG_BY_HOXA9_h Manually Curated H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 (external link) 79070 MYC (external link) Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
2033 DOWNREG_BY_HOXA9_h Manually Curated H001023_01 Info Mannosidase, alpha, class 2A, member 2 H001023_01 L28821 (external link) 295605 MAN2A2 (external link) ER associated degradation (ERAD) Pathway, Steps in the Glycosylation of Mammalian N-linked Oligosaccharides, N-Glycan biosynthesis 0.2111813 1.139
2034 DOWNREG_BY_HOXA9_h Manually Curated H003255_01 Info CDC37 (cell division cycle 37, S. cerevisiae, homolog) H003255_01 U43077 (external link) 160958 CDC37 (external link) 0.2178008 0.878
2035 DOWNREG_BY_HOXA9_h Manually Curated H000068_01 Info Signal recognition particle 72kD H000068_01 AF069765 (external link) 237825 SRP72 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.2609516 0.897
2036 DOWNREG_BY_HOXA9_h Manually Curated H012741_01 Info Glutaredoxin (thioltransferase) H012741_01 AF069668 (external link) 28988 GLRX (external link) pharmacology 0.2704585 1.145
2037 DOWNREG_BY_HOXA9_h Manually Curated H006807_01 Info Cytokine inducible SH2-containing protein H006807_01 AF132297 (external link) 8257 CISH (external link) Growth Hormone Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, immunology 0.3746206 0.888
2038 DOWNREG_BY_HOXA9_h Manually Curated H006584_01 Info Splicing factor, arginine/serine-rich 11 H006584_01 M74002 (external link) 11482 SFRS11 (external link) 0.4576641 1.062
2039 DOWNREG_BY_HOXA9_h Manually Curated H016588_01 Info Hypothetical protein DKFZp761B2423 H016588_01 AK026954 (external link) 91065 DKFZp761B2423 (external link) 0.6339659 1.046
2040 DOWNREG_BY_HOXA9_h Manually Curated H010792_01 Info Dynein, cytoplasmic, light intermediate polypeptide 2 H010792_01 AF035812 (external link) 194625 DNCLI2 (external link) 0.6511108 1.058
2041 DOWNREG_BY_HOXA9_h Manually Curated H002850_01 Info Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 (external link) 431 BMI1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc 0.7846354 0.976
2042 DOWNREG_BY_HOXA9_h Manually Curated H003618_01 Info Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) H003618_01 D17547 (external link) 301865 DCT (external link) Tyrosine metabolism 0.9648525 0.996
2043 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H006300_01 Info Hypothetical protein FLJ23239 H006300_01 AL137600 (external link) 34516 FLJ23239 (external link) Glycosphingolipid metabolism 0.0007944 0.727
2044 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H008949_01 Info Hypothetical protein H008949_01 AF151024 (external link) 122492 LOC51237 (external link) 0.0022423 1.318
2045 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H000309_01 Info CAMP response element-binding protein CRE-BPa H000309_01 L05515 (external link) 149 H_GS165L15.1 (external link) 0.0078273 1.479
2046 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003611_01 Info Mitogen-activated protein kinase kinase 4 H003611_01 L36870 (external link) 75217 MAP2K4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system 0.012502 0.753
2047 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H001062_01 Info N-acylsphingosine amidohydrolase (acid ceramidase) H001062_01 U70063 (external link) 75811 ASAH (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … 0.0187984 1.357
2048 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003130_01 Info Interleukin 8 receptor, beta H003130_01 L19593 (external link) 846 IL8RB (external link) immunology 0.0345675 1.307
2049 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003628_01 Info Dystroglycan 1 (dystrophin-associated glycoprotein 1) H003628_01 L19711 (external link) 76111 DAG1 (external link) Agrin in Postsynaptic Differentiation, immunology 0.034627 0.774
2050 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H001748_01 Info Inositol 1,4,5-trisphosphate 3-kinase B H001748_01 X57206 (external link) 78877 ITPKB (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction 0.1283627 0.851
2051 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
2052 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H001718_01 Info Inositol 1,4,5-trisphosphate 3-kinase A H001718_01 X54938 (external link) 2722 ITPKA (external link) Inositol phosphate metabolism, Phosphatidylinositol signaling system 0.1331494 1.16
2053 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003878_01 Info Caspase 3, apoptosis-related cysteine protease H003878_01 U13737 (external link) 74552 CASP3 (external link) Apoptotic DNA fragmentation and tissue homeostasis, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, TNFR1 Signaling Pathway, TSP-1 Induced Apoptosis in Microvascular Endothelial Cell , apoptosis, immunology 0.1364651 1.175
2054 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 (external link) 110299 MAP2K7 (external link) Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
2055 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H012904_01 Info Mitogen-activated protein kinase 8 interacting protein 3 H012904_01 AB028989 (external link) 88500 MAPK8IP3 (external link) 0.3112914 1.095
2056 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H011336_01 Info Guanine nucleotide binding protein (G protein), q polypeptide H011336_01 U43083 (external link) 296261 GNAQ (external link) Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology 0.3713616 0.89
2057 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H014634_01 Info Homo sapiens mRNA for FLJ00027 protein, partial CDS H014634_01 AK024437 (external link) 199417 0.6135149 1.048
2058 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H006635_01 Info Homo sapiens clone 23607 mRNA sequence H006635_01 AF038181 (external link) 167825 ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc 0.6181322 1.041
2059 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003651_01 Info EphB2 H003651_01 AF025304 (external link) 125124 EPHB2 (external link) development 0.7855294 0.971
2060 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 (external link) 79194 CREB1 (external link) Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
2061 ST_GRANULE_CELL_SURVIVAL_PATHWAY_h Signalling Transduction KE H014820_01 Info Mitogen-activated protein kinase 9 H014820_01 NM_002752 (external link) 246857 MAPK9 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.9883614 0.998
2062 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
2063 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002893_01 Info V-raf-1 murine leukemia viral oncogene homolog 1 H002893_01 X03484 (external link) 85181 RAF1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … 0.0062484 1.596
2064 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002878_01 Info V-yes-1 Yamaguchi sarcoma viral related oncogene homolog H002878_01 M16038 (external link) 80887 LYN (external link) BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc 0.0068841 1.545
2065 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2066 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H001365_01 Info Protein kinase C, beta 1 H001365_01 X07109 (external link) 77202 PRKCB1 (external link) Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction 0.0304335 1.379
2067 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
2068 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003158_01 Info Mitogen-activated protein kinase 8 H003158_01 L26318 (external link) 190913 MAPK8 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … 0.1287835 1.166
2069 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002501_01 Info Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) H002501_01 D25274 (external link) 173737 RAC1 (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments 0.1980127 1.118
2070 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003870_01 Info Bruton agammaglobulinemia tyrosine kinase H003870_01 NM_000061 (external link) 159494 BTK (external link) BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction 0.251649 1.148
2071 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H001979_01 Info Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) H001979_01 M29551 (external link) 151531 PPP3CB (external link) cell_cycle, cell_signaling 0.3386238 0.898
2072 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003578_01 Info Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) H003578_01 S46622 (external link) 75206 PPP3CC (external link) 0.5197011 0.934
2073 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002045_01 Info Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 H002045_01 U80917 (external link) 96149 NFATC1 (external link) BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology 0.623508 1.051
2074 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002470_01 Info Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 H002470_01 L41067 (external link) 172674 NFATC3 (external link) immunology 0.7190859 0.97
2075 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2076 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H003499_01 Info CD79B antigen (immunoglobulin-associated beta) H003499_01 M89957 (external link) 89575 CD79B (external link) B Cell Receptor Complex, BCR Signaling Pathway, CTCF: First Multivalent Nuclear Factor, immunology 0.8100034 1.033
2077 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H002404_01 Info Synaptotagmin I H002404_01 M55047 (external link) 154679 SYT1 (external link) 0.8170962 0.971
2078 bcrPathway_h B cell antigen receptors (BCRs) activate tyrosine kinases and transiently increase tyrosine phosphorylation on binding to antigen. H000579_01 Info Calmodulin 2 (phosphorylase kinase, delta) H000579_01 D45887 (external link) 182278 CALM2 (external link) 0.9689776 1.004
2079 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 (external link) 77432 EGFR (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
2080 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2081 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 (external link) 20084 RXRA (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
2082 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002882_01 Info Nuclear receptor co-repressor 2 H002882_01 NM_006312 (external link) 287994 NCOR2 (external link) CARM1 and Regulation of the Estrogen Receptor, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), METS affect on Macrophage Differentiation, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells 0.3492591 0.931
2083 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002907_01 Info Retinoic acid receptor, alpha H002907_01 X06614 (external link) 250505 RARA (external link) Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development 0.4825926 1.084
2084 egfr_smrtePathway_h EGF receptor activation inhibits SMRT, a transcriptional co-repressor that interacts with transcription factor complexes and gene silencers. H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2085 HEMO_TF_LIST_JP_h Manually Curated H003463_01 Info Spleen focus forming virus (SFFV) proviral integration oncogene spi1 H003463_01 X52056 (external link) 157441 SPI1 (external link) tsonc 0.0010958 1.855
2086 HEMO_TF_LIST_JP_h Manually Curated H002186_01 Info Serum response factor (c-fos serum response element-binding transcription factor) H002186_01 J03161 (external link) 155321 SRF (external link) EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription 0.0017465 0.722
2087 HEMO_TF_LIST_JP_h Manually Curated H001284_01 Info Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) H001284_01 L04731 (external link) 199160 MLL (external link) misc 0.0019854 0.707
2088 HEMO_TF_LIST_JP_h Manually Curated H003948_01 Info Nuclear factor (erythroid-derived 2), 45kD H003948_01 S77763 (external link) 75643 NFE2 (external link) gene_regulation, immunology, transcription 0.0024537 1.435
2089 HEMO_TF_LIST_JP_h Manually Curated H000570_01 Info CREB binding protein (Rubinstein-Taybi syndrome) H000570_01 U47741 (external link) 23598 CREBBP (external link) gene_regulation, transcription 0.0048718 1.469
2090 HEMO_TF_LIST_JP_h Manually Curated H000640_01 Info Ets variant gene 4 (E1A enhancer-binding protein, E1AF) H000640_01 U18018 (external link) 77711 ETV4 (external link) gene_regulation, immunology, transcription 0.0049082 0.628
2091 HEMO_TF_LIST_JP_h Manually Curated H013956_01 Info Kruppel-like factor 1 (erythroid) H013956_01 U65404 (external link) 37860 KLF1 (external link) 0.0114587 1.338
2092 HEMO_TF_LIST_JP_h Manually Curated H001315_01 Info Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) H001315_01 D43968 (external link) 129914 RUNX1 (external link) 0.0288879 0.822
2093 HEMO_TF_LIST_JP_h Manually Curated H007370_01 Info Kruppel-like factor 13 H007370_01 NM_015995 (external link) 7104 KLF13 (external link) 0.0315326 1.302
2094 HEMO_TF_LIST_JP_h Manually Curated H002057_01 Info Zinc finger protein 42 (myeloid-specific retinoic acid- responsive) H002057_01 AF055078 (external link) 169832 ZNF42 (external link) gene_regulation, transcription 0.0372699 0.808
2095 HEMO_TF_LIST_JP_h Manually Curated H016113_01 Info Homeo box B8 H016113_01 NM_024016 (external link) 324916 HOXB8 (external link) development 0.0540634 1.307
2096 HEMO_TF_LIST_JP_h Manually Curated H002315_01 Info Transcription factor AP-4 (activating enhancer-binding protein 4) H002315_01 S73885 (external link) 3005 TFAP4 (external link) gene_regulation, transcription 0.0600253 0.853
2097 HEMO_TF_LIST_JP_h Manually Curated H000315_01 Info Nuclear factor I/C (CCAAT-binding transcription factor) H000315_01 X12492 (external link) 184771 NFIC (external link) 0.07748 0.815
2098 HEMO_TF_LIST_JP_h Manually Curated H002168_01 Info GATA-binding protein 2 H002168_01 M68891 (external link) 760 GATA2 (external link) gene_regulation, misc, transcription 0.0841754 0.806
2099 HEMO_TF_LIST_JP_h Manually Curated H000251_01 Info Mediterranean fever H000251_01 AF018080 (external link) 173730 MEFV (external link) 0.0879179 1.152
2100 HEMO_TF_LIST_JP_h Manually Curated H008525_01 Info Homo sapiens cDNA FLJ12900 fis, clone NT2RP2004321 H008525_01 AL049381 (external link) 21851 Perou’s – Intrinsic – Breast-Cancer-Genes, development, gene_regulation, transcription 0.0950204 0.767
2101 HEMO_TF_LIST_JP_h Manually Curated H001313_01 Info Hematopoietically expressed homeobox H001313_01 L16499 (external link) 118651 HHEX (external link) misc, transcription 0.110793 1.2
2102 HEMO_TF_LIST_JP_h Manually Curated H003249_01 Info V-ets avian erythroblastosis virus E26 oncogene homolog 1 H003249_01 X14798 (external link) 248109 ETS1 (external link) Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc 0.1428371 0.878
2103 HEMO_TF_LIST_JP_h Manually Curated H003550_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) H003550_01 S76638 (external link) 73090 NFKB2 (external link) gene_regulation, immunology, transcription, tsonc 0.1593331 1.165
2104 HEMO_TF_LIST_JP_h Manually Curated H001297_01 Info Pre-B-cell leukemia transcription factor 1 H001297_01 M86546 (external link) 155691 PBX1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, development, gene_regulation, transcription 0.1724831 1.132
2105 HEMO_TF_LIST_JP_h Manually Curated H002091_01 Info V-myc avian myelocytomatosis viral oncogene homolog H002091_01 K02276 (external link) 79070 MYC (external link) Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc 0.1797519 0.824
2106 HEMO_TF_LIST_JP_h Manually Curated H013484_01 Info H2.0 (Drosophila)-like homeo box 1 H013484_01 M60721 (external link) 74870 HLX1 (external link) immunology 0.1970503 1.197
2107 HEMO_TF_LIST_JP_h Manually Curated H003787_01 Info LIM domain only 2 (rhombotin-like 1) H003787_01 X61118 (external link) 184585 LMO2 (external link) 0.2060088 1.164
2108 HEMO_TF_LIST_JP_h Manually Curated H015892_01 Info Early development regulator 1 (homolog of polyhomeotic 1) H015892_01 NM_004426 (external link) 305985 EDR1 (external link) The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails 0.2199906 0.855
2109 HEMO_TF_LIST_JP_h Manually Curated H003656_01 Info Ets variant gene 6 (TEL oncogene) H003656_01 U11732 (external link) 169081 ETV6 (external link) immunology, tsonc 0.3132143 0.905
2110 HEMO_TF_LIST_JP_h Manually Curated H002611_01 Info Interferon regulatory factor 1 H002611_01 X14454 (external link) 80645 IRF1 (external link) gene_regulation, transcription 0.3284273 0.915
2111 HEMO_TF_LIST_JP_h Manually Curated H012191_01 Info Meis1 (mouse) homolog H012191_01 U85707 (external link) 170177 MEIS1 (external link) development 0.3687496 1.11
2112 HEMO_TF_LIST_JP_h Manually Curated H002241_01 Info POU domain, class 2, transcription factor 1 H002241_01 X13403 (external link) 182237 POU2F1 (external link) gene_regulation, misc, transcription 0.4573205 1.072
2113 HEMO_TF_LIST_JP_h Manually Curated H003580_01 Info Nuclear factor I/X (CCAAT-binding transcription factor) H003580_01 L31881 (external link) 35841 NFIX (external link) 0.4626847 0.927
2114 HEMO_TF_LIST_JP_h Manually Curated H011704_01 Info GATA-binding protein 1 (globin transcription factor 1) H011704_01 X17254 (external link) 765 GATA1 (external link) Hemoglobin\’s Chaperone, gene_regulation, misc, transcription 0.4642197 1.099
2115 HEMO_TF_LIST_JP_h Manually Curated H010176_01 Info Homeo box C4 H010176_01 X07495 (external link) 50895 HOXC4 (external link) development 0.5228139 0.945
2116 HEMO_TF_LIST_JP_h Manually Curated H007160_01 Info E2F transcription factor 2 H007160_01 L22846 (external link) 121487 E2F2 (external link) cell_cycle, gene_regulation, transcription 0.5789709 0.945
2117 HEMO_TF_LIST_JP_h Manually Curated H002518_01 Info Zinc finger protein, subfamily 1A, 1 (Ikaros) H002518_01 U40462 (external link) 54452 ZNFN1A1 (external link) 0.5915437 0.94
2118 HEMO_TF_LIST_JP_h Manually Curated H009346_01 Info AML1 H009346_01 S76346 (external link) 166060 0.6048212 1.054
2119 HEMO_TF_LIST_JP_h Manually Curated H012261_01 Info Homeo box C6 H012261_01 M16938 (external link) 820 HOXC6 (external link) development 0.6427939 0.963
2120 HEMO_TF_LIST_JP_h Manually Curated H002070_01 Info Transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) H002070_01 M31523 (external link) 101047 TCF3 (external link) gene_regulation, immunology, transcription 0.6844305 0.958
2121 HEMO_TF_LIST_JP_h Manually Curated H014209_01 Info Homo sapiens NOTCH 1 (N1) mRNA, complete CDS H014209_01 AF308602 (external link) 129053 Presenilin action in Notch and Wnt signaling, Proteolysis and Signaling Pathway of Notch , Segmentation Clock, immunology 0.7088381 1.031
2122 HEMO_TF_LIST_JP_h Manually Curated H007855_01 Info Kreisler (mouse) maf-related leucine zipper homolog H007855_01 NM_005461 (external link) 169487 KRML (external link) 0.7205744 0.957
2123 HEMO_TF_LIST_JP_h Manually Curated H002850_01 Info Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 (external link) 431 BMI1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc 0.7846354 0.976
2124 HEMO_TF_LIST_JP_h Manually Curated H007065_01 Info Growth factor independent 1 H007065_01 U67369 (external link) 73172 GFI1 (external link) immunology 0.8418068 0.979
2125 HEMO_TF_LIST_JP_h Manually Curated H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2126 HEMO_TF_LIST_JP_h Manually Curated H000647_01 Info E74-like factor 1 (ets domain transcription factor) H000647_01 M82882 (external link) 154365 ELF1 (external link) gene_regulation, transcription 0.879249 1.014
2127 HEMO_TF_LIST_JP_h Manually Curated H003151_01 Info E1A binding protein p300 H003151_01 U01877 (external link) 25272 EP300 (external link) Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
2128 HEMO_TF_LIST_JP_h Manually Curated H000247_01 Info Sp3 transcription factor H000247_01 X68560 (external link) 44450 SP3 (external link) Effects of calcineurin in Keratinocyte Differentiation, Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.985621 0.998
2129 HEMO_TF_LIST_JP_h Manually Curated H005603_01 Info High-mobility group (nonhistone chromosomal) protein 4 H005603_01 Y10043 (external link) 19114 HMG4 (external link) 0.9931402 1.001
2130 hcmvPathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2131 hcmvPathway_h BioCarta H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 (external link) 180533 MAP2K3 (external link) fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
2132 hcmvPathway_h BioCarta H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2133 hcmvPathway_h BioCarta H003259_01 Info Sp1 transcription factor H003259_01 J03133 (external link) 2021 SP1 (external link) Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation 0.0557417 0.814
2134 hcmvPathway_h BioCarta H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
2135 hcmvPathway_h BioCarta H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 (external link) 72241 MAP2K2 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
2136 hcmvPathway_h BioCarta H003612_01 Info V-akt murine thymoma viral oncogene homolog 1 H003612_01 M63167 (external link) 71816 AKT1 (external link) Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … 0.6741257 1.038
2137 hcmvPathway_h BioCarta H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2138 hcmvPathway_h BioCarta H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2139 hcmvPathway_h BioCarta H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 (external link) 79194 CREB1 (external link) Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway, Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
2140 hcmvPathway_h BioCarta H002963_01 Info V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide H002963_01 L19067 (external link) 75569 RELA (external link) Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc 0.9724165 1.003
2141 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H002486_01 Info Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) H002486_01 M90299 (external link) 1270 GCK (external link) Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology 0.0014569 1.288
2142 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H004823_01 Info Aldolase C, fructose-bisphosphate H004823_01 AF054987 (external link) 155247 ALDOC (external link) Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway 0.001576 0.707
2143 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H004836_01 Info GDP-mannose pyrophosphorylase A H004836_01 AK000999 (external link) 27059 GMPPA (external link) Fructose and mannose metabolism 0.00381 0.698
2144 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H003374_01 Info Aldolase A, fructose-bisphosphate H003374_01 M11560 (external link) 273415 ALDOA (external link) Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology 0.0300936 1.252
2145 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H001522_01 Info Aldo-keto reductase family 1, member B1 (aldose reductase) H001522_01 X15414 (external link) 75313 AKR1B1 (external link) Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Pentose and glucuronate interconversions, Pyruvate metabolism 0.0453087 0.846
2146 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H001387_01 Info Phosphofructokinase, platelet H001387_01 D25328 (external link) 99910 PFKP (external link) Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.101431 0.866
2147 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H005470_01 Info Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial CDS H005470_01 AL162062 (external link) 198182 0.1944956 1.125
2148 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H011651_01 Info 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 H011651_01 X52638 (external link) 739 PFKFB1 (external link) Fructose and mannose metabolism 0.2588895 1.131
2149 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H001378_01 Info Phosphofructokinase, muscle H001378_01 U24183 (external link) 75160 PFKM (external link) Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.2927445 0.908
2150 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H001535_01 Info Sorbitol dehydrogenase H001535_01 L29008 (external link) 878 SORD (external link) Fructose and mannose metabolism, metabolism 0.3484797 1.082
2151 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H005772_01 Info Phosphomannomutase 2 H005772_01 U85773 (external link) 154695 PMM2 (external link) Fructose and mannose metabolism 0.9121231 0.987
2152 MAP00051_Fructose_and_mannose_metabolism_h GenMAPP (external link) H001385_01 Info Phosphofructokinase, liver H001385_01 X15573 (external link) 155455 PFKL (external link) Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology 0.9581627 1.005
2153 MAP_kinase_kinase_activity_h GenMAPP H003200_01 Info Mitogen-activated protein kinase kinase 3 H003200_01 D87116 (external link) 180533 MAP2K3 (external link) fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway 0.0009666 1.561
2154 MAP_kinase_kinase_activity_h GenMAPP H002895_01 Info Mitogen-activated protein kinase 14 H002895_01 L35263 (external link) 79107 MAPK14 (external link) BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … 0.0086925 1.429
2155 MAP_kinase_kinase_activity_h GenMAPP H003309_01 Info Mitogen-activated protein kinase kinase 7 H003309_01 AF013589 (external link) 110299 MAP2K7 (external link) Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway 0.3044184 1.088
2156 MAP_kinase_kinase_activity_h GenMAPP H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2157 MAP_kinase_kinase_activity_h GenMAPP H002580_01 Info Mitogen-activated protein kinase-activated protein kinase 3 H002580_01 U09578 (external link) 227789 MAPKAPK3 (external link) MAP Kinase Signaling Pathway, Stress Induction of HSP Regulation, immunology 0.8269383 0.981
2158 LEU_UP_h Peng_et_al_2002 H001704_01 Info Protein phosphatase 2, regulatory subunit B (B56), gamma isoform H001704_01 U37352 (external link) 171734 PPP2R5C (external link) signal_transduction 0.0003843 0.708
2159 LEU_UP_h Peng_et_al_2002 H000670_01 Info Interferon stimulated gene (20kD) H000670_01 U88964 (external link) 183487 ISG20 (external link) cell_cycle, cell_signaling 0.0004988 1.6
2160 LEU_UP_h Peng_et_al_2002 H002552_01 Info Integrin beta 3 binding protein (beta3-endonexin) H002552_01 U37139 (external link) 82084 ITGB3BP (external link) 0.0013566 0.728
2161 LEU_UP_h Peng_et_al_2002 H009875_01 Info Lysosomal-associated multispanning membrane protein-5 H009875_01 U51240 (external link) 79356 LAPTM5 (external link) 0.0035021 1.539
2162 LEU_UP_h Peng_et_al_2002 H002398_01 Info CD22 antigen H002398_01 X59350 (external link) 171763 CD22 (external link) angiogenesis, immunology, metastasis 0.0039052 1.468
2163 LEU_UP_h Peng_et_al_2002 H003036_01 Info Bone morphogenetic protein 7 (osteogenic protein 1) H003036_01 X51801 (external link) 170195 BMP7 (external link) ALK in cardiac myocytes, development 0.0073416 0.679
2164 LEU_UP_h Peng_et_al_2002 H011715_01 Info Plexin B2 H011715_01 AB002313 (external link) 3989 PLXNB2 (external link) 0.0128867 1.248
2165 LEU_UP_h Peng_et_al_2002 H009608_01 Info Absent in melanoma 1 H009608_01 U83115 (external link) 161002 AIM1 (external link) 0.0140873 1.306
2166 LEU_UP_h Peng_et_al_2002 H003493_01 Info MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) H003493_01 X63380 (external link) 78881 MEF2B (external link) 0.0145042 1.328
2167 LEU_UP_h Peng_et_al_2002 H012762_01 Info POU transcription factor H012762_01 NM_014352 (external link) 227115 11-Oct (external link) 0.0161056 1.229
2168 LEU_UP_h Peng_et_al_2002 H009473_01 Info DKFZP586D0623 protein H009473_01 AL050197 (external link) 44468 DKFZP586D0623 (external link) 0.034552 1.201
2169 LEU_UP_h Peng_et_al_2002 H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
2170 LEU_UP_h Peng_et_al_2002 H008794_01 Info Prostate cancer overexpressed gene 1 H008794_01 AF045584 (external link) 18910 POV1 (external link) 0.0472666 0.794
2171 LEU_UP_h Peng_et_al_2002 H008614_01 Info Cold inducible RNA-binding protein H008614_01 D78134 (external link) 119475 CIRBP (external link) 0.0552495 1.222
2172 LEU_UP_h Peng_et_al_2002 H009951_01 Info Exportin, tRNA (nuclear export receptor for tRNAs) H009951_01 AF039022 (external link) 85951 XPOT (external link) 0.0554912 0.798
2173 LEU_UP_h Peng_et_al_2002 H000887_01 Info Prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) H000887_01 J03077 (external link) 78575 PSAP (external link) immunology 0.0585383 1.205
2174 LEU_UP_h Peng_et_al_2002 H010777_01 Info Unc119 (C.elegans) homolog H010777_01 AF028789 (external link) 81728 UNC119 (external link) 0.0677067 1.248
2175 LEU_UP_h Peng_et_al_2002 H014131_01 Info Microtubule-associated proteins 1A/1B light chain 3 H014131_01 NM_022818 (external link) 121849 MAP1A/1BLC3 (external link) 0.0790174 1.225
2176 LEU_UP_h Peng_et_al_2002 H002361_01 Info Casein kinase 1, gamma 2 H002361_01 U89896 (external link) 181390 CSNK1G2 (external link) 0.0815742 0.849
2177 LEU_UP_h Peng_et_al_2002 H000564_01 Info Protein kinase C binding protein 1 H000564_01 AB032951 (external link) 75871 PRKCBP1 (external link) 0.0986503 0.835
2178 LEU_UP_h Peng_et_al_2002 H000999_01 Info Glycosylphosphatidylinositol specific phospholipase D1 H000999_01 L11702 (external link) 272529 GPLD1 (external link) ADP-Ribosylation Factor 0.0992549 1.126
2179 LEU_UP_h Peng_et_al_2002 H000172_01 Info Kinesin-like 6 (mitotic centromere-associated kinesin) H000172_01 U63743 (external link) 69360 KNSL6 (external link) 0.1008966 0.82
2180 LEU_UP_h Peng_et_al_2002 H011237_01 Info Methionine-tRNA synthetase H011237_01 X94754 (external link) 279946 MARS (external link) Aminoacyl-tRNA synthetases, Methionine metabolism, Selenoamino acid metabolism 0.1030499 0.862
2181 LEU_UP_h Peng_et_al_2002 H002491_01 Info Bone morphogenetic protein 1 H002491_01 NM_006129 (external link) 1274 BMP1 (external link) development 0.1079128 0.821
2182 LEU_UP_h Peng_et_al_2002 H002418_01 Info Fc fragment of IgE, low affinity II, receptor for (CD23A) H002418_01 M15059 (external link) 1416 FCER2 (external link) immunology 0.1086867 1.218
2183 LEU_UP_h Peng_et_al_2002 H000998_01 Info Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 H000998_01 AB018010 (external link) 79748 SLC3A2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.1156436 0.843
2184 LEU_UP_h Peng_et_al_2002 H003890_01 Info Myelin associated glycoprotein H003890_01 M29273 (external link) 1780 MAG (external link) 0.1166451 1.147
2185 LEU_UP_h Peng_et_al_2002 H012158_01 Info Upregulated by 1,25-dihydroxyvitamin D-3 H012158_01 S73591 (external link) 179526 VDUP1 (external link) 0.1293789 1.193
2186 LEU_UP_h Peng_et_al_2002 H003118_01 Info Interferon regulatory factor 2 H003118_01 NM_002199 (external link) 83795 IRF2 (external link) gene_regulation, transcription 0.1483763 1.175
2187 LEU_UP_h Peng_et_al_2002 H011942_01 Info Activating transcription factor 5 H011942_01 AB021663 (external link) 9754 ATF5 (external link) 0.1666639 1.141
2188 LEU_UP_h Peng_et_al_2002 H002429_01 Info Tumor necrosis factor receptor superfamily, member 7 H002429_01 M63928 (external link) 180841 TNFRSF7 (external link) immunology 0.1865182 1.133
2189 LEU_UP_h Peng_et_al_2002 H007340_01 Info Putative translation initiation factor H007340_01 AL050005 (external link) 150580 SUI1 (external link) 0.2203743 0.897
2190 LEU_UP_h Peng_et_al_2002 H003820_01 Info Lymphocyte-specific protein tyrosine kinase H003820_01 X05027 (external link) 1765 LCK (external link) Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc 0.2266863 0.873
2191 LEU_UP_h Peng_et_al_2002 H001256_01 Info Sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) H001256_01 X74570 (external link) 75268 SIAT4C (external link) 0.2276302 0.892
2192 LEU_UP_h Peng_et_al_2002 H013590_01 Info Nuclear receptor co-repressor 1 H013590_01 AF044209 (external link) 144904 NCOR1 (external link) Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) 0.2336483 0.899
2193 LEU_UP_h Peng_et_al_2002 H001713_01 Info S100 calcium-binding protein A11 (calgizzarin) H001713_01 D38583 (external link) 256290 S100A11 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes 0.2360494 1.115
2194 LEU_UP_h Peng_et_al_2002 H010167_01 Info GTP cyclohydrolase I feedback regulatory protein H010167_01 NM_005258 (external link) 83081 GCHFR (external link) 0.2423472 1.112
2195 LEU_UP_h Peng_et_al_2002 H000426_01 Info Adaptor protein with pleckstrin homology and src homology 2 domains H000426_01 AB000520 (external link) 105052 APS (external link) 0.252114 1.104
2196 LEU_UP_h Peng_et_al_2002 H009957_01 Info KIAA0770 protein H009957_01 AB018313 (external link) 9452 KIAA0770 (external link) 0.2820493 1.119
2197 LEU_UP_h Peng_et_al_2002 H000515_01 Info Lymphoid-restricted membrane protein H000515_01 U10485 (external link) 40202 LRMP (external link) misc 0.2845333 1.106
2198 LEU_UP_h Peng_et_al_2002 H014122_01 Info Poly(rC)-binding protein 3 H014122_01 NM_020528 (external link) 121241 PCBP3 (external link) 0.3199569 1.111
2199 LEU_UP_h Peng_et_al_2002 H004471_01 Info Chromosome 22 open reading frame 1 H004471_01 U84894 (external link) 159538 C22ORF1 (external link) 0.3224188 0.908
2200 LEU_UP_h Peng_et_al_2002 H012354_01 Info Argininosuccinate synthetase H012354_01 X01630 (external link) 160786 ASS (external link) Alanine and aspartate metabolism, Arginine and proline metabolism, Urea cycle and metabolism of amino groups 0.3231469 1.108
2201 LEU_UP_h Peng_et_al_2002 H008885_01 Info Arginine-glutamic acid dipeptide (RE) repeats H008885_01 AB007927 (external link) 194369 RERE (external link) Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline 0.4084586 0.922
2202 LEU_UP_h Peng_et_al_2002 H003935_01 Info KIAA0922 protein H003935_01 AB023139 (external link) 37892 KIAA0922 (external link) 0.4306564 1.134
2203 LEU_UP_h Peng_et_al_2002 H001583_01 Info Isocitrate dehydrogenase 2 (NADP+), mitochondrial H001583_01 X69433 (external link) 5337 IDH2 (external link) Citrate cycle (TCA cycle), Glutathione metabolism, Reductive carboxylate cycle (CO2 fixation) 0.4311395 0.932
2204 LEU_UP_h Peng_et_al_2002 H010281_01 Info KIAA1330 protein H010281_01 AB037751 (external link) 301242 KIAA1330 (external link) 0.4359424 0.887
2205 LEU_UP_h Peng_et_al_2002 H009376_01 Info ORF H009376_01 M68864 (external link) 77868 LOC51035 (external link) 0.4511731 1.055
2206 LEU_UP_h Peng_et_al_2002 H009071_01 Info HS1 binding protein H009071_01 U68566 (external link) 15318 HAX1 (external link) 0.4562948 0.927
2207 LEU_UP_h Peng_et_al_2002 H002039_01 Info Phosphoenolpyruvate carboxykinase 2 (mitochondrial) H002039_01 X92720 (external link) 75812 PCK2 (external link) Citrate cycle (TCA cycle), Pyruvate metabolism 0.4857451 0.932
2208 LEU_UP_h Peng_et_al_2002 H004208_01 Info Excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pig H004208_01 AF041410 (external link) 99987 ERCC2 (external link) 0.5075942 1.062
2209 LEU_UP_h Peng_et_al_2002 H007025_01 Info Homo sapiens mRNA; cDNA DKFZp434H2418 (from clone DKFZp434H2418) H007025_01 AL133636 (external link) 274252 0.5107696 1.077
2210 LEU_UP_h Peng_et_al_2002 H000840_01 Info Signal sequence receptor, beta (translocon-associated protein beta) H000840_01 NM_003145 (external link) 74564 SSR2 (external link) 0.5124039 0.937
2211 LEU_UP_h Peng_et_al_2002 H007319_01 Info Histone deacetylase 5 H007319_01 NM_005474 (external link) 9028 HDAC5 (external link) Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Regulation of PGC-1a 0.5427846 1.062
2212 LEU_UP_h Peng_et_al_2002 H004277_01 Info KIAA0801 gene product H004277_01 AB018344 (external link) 17585 KIAA0801 (external link) 0.6020006 0.947
2213 LEU_UP_h Peng_et_al_2002 H010714_01 Info Chloride channel 6 H010714_01 X83378 (external link) 211614 CLCN6 (external link) 0.6039191 0.953
2214 LEU_UP_h Peng_et_al_2002 H006566_01 Info Surfeit 1 H006566_01 Z35093 (external link) 3196 SURF1 (external link) immunology 0.6139479 1.054
2215 LEU_UP_h Peng_et_al_2002 H007902_01 Info FE65-LIKE 2 H007902_01 AB018247 (external link) 173103 FE65L2 (external link) 0.6201659 0.951
2216 LEU_UP_h Peng_et_al_2002 H000390_01 Info Microsomal glutathione S-transferase 2 H000390_01 U77604 (external link) 81874 MGST2 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Glutathione metabolism, pharmacology 0.6454088 1.048
2217 LEU_UP_h Peng_et_al_2002 H015369_01 Info Homo sapiens cDNA FLJ11961 fis, clone HEMBB1001020, highly similar to Homo sapiens mRNA for KIAA0889 H015369_01 AK022023 (external link) 287469 0.6728969 0.969
2218 LEU_UP_h Peng_et_al_2002 H002427_01 Info Calcium/calmodulin-dependent protein kinase I H002427_01 L41816 (external link) 184402 CAMK1 (external link) Actions of Nitric Oxide in the Heart, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Effects of calcineurin in Keratinocyte Differentiation, Endocytotic role of NDK, Phosphins and Dynamin, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Nitric Oxide Signaling Pathway, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of PGC-1a, Role of MEF2D in T-cell Apoptosis, Signal Dependent Regulation of Myogenesis by Corepressor MITR, Signaling Pathway from G-Protein Families, … 0.6744118 1.052
2219 LEU_UP_h Peng_et_al_2002 H000910_01 Info Solute carrier family 1 (neutral amino acid transporter), member 5 H000910_01 U53347 (external link) 183556 SLC1A5 (external link) immunology 0.7186183 0.971
2220 LEU_UP_h Peng_et_al_2002 H003776_01 Info Aldehyde dehydrogenase 2 family (mitochondrial) H003776_01 X05409 (external link) 195432 ALDH2 (external link) Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, immunology, pharmacology 0.7225282 0.971
2221 LEU_UP_h Peng_et_al_2002 H000419_01 Info Pleckstrin homology, Sec7 and coiled/coil domains 1(cytohesin 1) H000419_01 M85169 (external link) 1050 PSCD1 (external link) ADP-Ribosylation Factor 0.7795723 1.029
2222 LEU_UP_h Peng_et_al_2002 H002850_01 Info Murine leukemia viral (bmi-1) oncogene homolog H002850_01 L13689 (external link) 431 BMI1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc 0.7846354 0.976
2223 LEU_UP_h Peng_et_al_2002 H007376_01 Info Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 H007376_01 AL049932 (external link) 326248 0.785212 1.026
2224 LEU_UP_h Peng_et_al_2002 H001506_01 Info Pyrroline-5-carboxylate reductase 1 H001506_01 M77836 (external link) 79217 PYCR1 (external link) Arginine and proline metabolism, Urea cycle and metabolism of amino groups, immunology 0.8073734 0.973
2225 LEU_UP_h Peng_et_al_2002 H002397_01 Info Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase H002397_01 X16396 (external link) 154672 MTHFD2 (external link) Glyoxylate and dicarboxylate metabolism, One carbon pool by folate 0.8081788 0.975
2226 LEU_UP_h Peng_et_al_2002 H002721_01 Info Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) H002721_01 X62822 (external link) 2554 SIAT1 (external link) angiogenesis, metastasis 0.8087218 1.023
2227 LEU_UP_h Peng_et_al_2002 H001939_01 Info BTG family, member 2 H001939_01 U72649 (external link) 75462 BTG2 (external link) BTG family proteins and cell cycle regulation 0.8452859 0.981
2228 LEU_UP_h Peng_et_al_2002 H006441_01 Info Golgi-specific brefeldin A resistance factor 1 H006441_01 AF068755 (external link) 155499 GBF1 (external link) ADP-Ribosylation Factor 0.8714172 0.982
2229 LEU_UP_h Peng_et_al_2002 H000327_01 Info BTB and CNC homology 1, basic leucine zipper transcription factor 1 H000327_01 AB002803 (external link) 154276 BACH1 (external link) 0.881473 1.018
2230 LEU_UP_h Peng_et_al_2002 H004001_01 Info Trefoil factor 3 (intestinal) H004001_01 L15203 (external link) 82961 TFF3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Trefoil Factors Initiate Mucosal Healing 0.9010781 0.99
2231 LEU_UP_h Peng_et_al_2002 H001599_01 Info Prepronociceptin H001599_01 U48263 (external link) 89040 PNOC (external link) 0.9577235 1.006
2232 LEU_UP_h Peng_et_al_2002 H002511_01 Info KH-type splicing regulatory protein (FUSE binding protein 2) H002511_01 U94832 (external link) 91142 KHSRP (external link) 0.9705349 0.997
2233 LEU_UP_h Peng_et_al_2002 H008685_01 Info Metallothionein 2A H008685_01 V00594 (external link) 118786 MT2A (external link) 0.9730896 1.006
2234 LEU_UP_h Peng_et_al_2002 H000065_01 Info BCL2/adenovirus E1B 19kD-interacting protein 3-like H000065_01 AL132665 (external link) 132955 BNIP3L (external link) 0.9898676 0.999
2235 p53Pathway_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2236 p53Pathway_h BioCarta H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
2237 p53Pathway_h BioCarta H002789_01 Info Tumor protein p53 (Li-Fraumeni syndrome) H002789_01 NM_000546 (external link) 1846 TP53 (external link) Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc 0.0273242 1.207
2238 p53Pathway_h BioCarta H002599_01 Info Proliferating cell nuclear antigen H002599_01 M15796 (external link) 78996 PCNA (external link) p53 Signaling Pathway, cell_cycle, gene_regulation, transcription 0.0303031 0.732
2239 p53Pathway_h BioCarta H002149_01 Info Cyclin-dependent kinase inhibitor 1A (p21, Cip1) H002149_01 U03106 (external link) 179665 CDKN1A (external link) ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc 0.0349766 1.236
2240 p53Pathway_h BioCarta H002323_01 Info Cyclin E1 H002323_01 M74093 (external link) 9700 CCNE1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle 0.1107382 0.884
2241 p53Pathway_h BioCarta H003605_01 Info BCL2-associated X protein H003605_01 L22474 (external link) 159428 BAX (external link) Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.253339 0.907
2242 p53Pathway_h BioCarta H001999_01 Info Cyclin D1 (PRAD1: parathyroid adenomatosis 1) H001999_01 X59798 (external link) 82932 CCND1 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc 0.3215316 0.898
2243 p53Pathway_h BioCarta H000475_01 Info Apoptotic protease activating factor H000475_01 NM_013229 (external link) 77579 APAF1 (external link) Apoptotic Signaling in Response to DNA Damage, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , p53 Signaling Pathway, Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, Trefoil Factors Initiate Mucosal Healing, apoptosis, immunology 0.7764943 0.97
2244 p53Pathway_h BioCarta H006841_01 Info Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) H006841_01 AL049301 (external link) 278577 Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology 0.7810094 0.98
2245 p53Pathway_h BioCarta H003766_01 Info Mouse double minute 2, human homolog of; p53-binding protein H003766_01 M92424 (external link) 170027 MDM2 (external link) ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc 0.8018001 0.978
2246 ppargPathway_h BioCarta H002547_01 Info Lipoprotein lipase H002547_01 M15856 (external link) 180878 LPL (external link) Low-density lipoprotein (LDL) pathway during atherogenesis, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome, Glycerolipid metabolism, immunology 0.0011159 0.719
2247 ppargPathway_h BioCarta H000570_01 Info CREB binding protein (Rubinstein-Taybi syndrome) H000570_01 U47741 (external link) 23598 CREBBP (external link) gene_regulation, transcription 0.0048718 1.469
2248 ppargPathway_h BioCarta H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 (external link) 20084 RXRA (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
2249 ppargPathway_h BioCarta H001374_01 Info PPAR binding protein H001374_01 Y13467 (external link) 15589 PPARBP (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, CARM1 and Regulation of the Estrogen Receptor, Control of Gene Expression by Vitamin D Receptor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Multi-step Regulation of Transcription by Pitx2, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis 0.0333785 0.803
2250 ppargPathway_h BioCarta H000245_01 Info Peroxisome proliferative activated receptor, gamma H000245_01 L40904 (external link) 100724 PPARG (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Nuclear Receptors in Lipid Metabolism and Toxicity, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Visceral Fat Deposits and the Metabolic Syndrome 0.7837641 0.944
2251 ppargPathway_h BioCarta H003151_01 Info E1A binding protein p300 H003151_01 U01877 (external link) 25272 EP300 (external link) Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription 0.9607239 1.004
2252 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002055_01 Info Growth factor receptor-bound protein 2 H002055_01 M96995 (external link) 296381 GRB2 (external link) Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … 0.0022348 1.459
2253 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H015306_01 Info Core promoter element binding protein H015306_01 NM_001300 (external link) 285313 COPEB (external link) 0.0052134 1.473
2254 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H001868_01 Info Dual specificity phosphatase 9 H001868_01 Y08302 (external link) 144879 DUSP9 (external link) Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases 0.0053314 0.725
2255 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002763_01 Info Mitogen-activated protein kinase kinase kinase 8 H002763_01 D14497 (external link) 248 MAP3K8 (external link) MAP Kinase Signaling Pathway 0.005954 1.333
2256 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H000309_01 Info CAMP response element-binding protein CRE-BPa H000309_01 L05515 (external link) 149 H_GS165L15.1 (external link) 0.0078273 1.479
2257 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H004258_01 Info Elongation factor-2 kinase H004258_01 U93850 (external link) 259855 HSU93850 (external link) Eukaryotic protein translation 0.0132437 0.748
2258 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002890_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 1 H002890_01 L07597 (external link) 149957 RPS6KA1 (external link) Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system 0.0138896 1.42
2259 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H000612_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 3 H000612_01 U08316 (external link) 173965 RPS6KA3 (external link) MAP Kinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system 0.0473043 0.79
2260 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H011228_01 Info G protein-coupled receptor kinase 7 H011228_01 AL137615 (external link) 261828 GPRK7 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system 0.0572981 1.27
2261 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H000521_01 Info Ribosomal protein S6 kinase, 90kD, polypeptide 2 H000521_01 X85106 (external link) 301664 RPS6KA2 (external link) MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction 0.0604408 1.207
2262 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H003178_01 Info Mitogen-activated protein kinase 3 H003178_01 X60188 (external link) 861 MAPK3 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … 0.0986041 1.184
2263 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002943_01 Info V-raf murine sarcoma viral oncogene homolog B1 H002943_01 M95712 (external link) 622 BRAF (external link) MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc 0.2376595 0.895
2264 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002405_01 Info Mitogen-activated protein kinase kinase 2 H002405_01 L11285 (external link) 72241 MAP2K2 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor 0.3118803 1.093
2265 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002565_01 Info TNF receptor-associated factor 3 H002565_01 U21092 (external link) 297660 TRAF3 (external link) CD40L Signaling Pathway, TACI and BCMA stimulation of B cell immune responses., TNFR2 Signaling Pathway, immunology 0.3225034 1.104
2266 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H001974_01 Info BCL2-antagonist of cell death H001974_01 U66879 (external link) 76366 BAD (external link) AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development 0.6985187 0.954
2267 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H002722_01 Info Mitogen-activated protein kinase kinase 1 H002722_01 L11284 (external link) 3446 MAP2K1 (external link) Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … 0.7377933 0.973
2268 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H003711_01 Info Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) H003711_01 M58603 (external link) 83428 NFKB1 (external link) Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … 0.8665095 1.017
2269 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H003163_01 Info CAMP responsive element binding protein 1 H003163_01 M27691 (external link) 79194 CREB1 (external link) Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology 0.9300928 1.009
2270 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H012856_01 Info MAP kinase-interacting serine/threonine kinase 1 H012856_01 AB000409 (external link) 5591 MKNK1 (external link) Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system 0.9455231 0.992
2271 ST_ERK1_ERK2_MAPK_Pathway_h Signalling Transduction KE H001715_01 Info Dual specificity phosphatase 4 H001715_01 AL137704 (external link) 2359 DUSP4 (external link) Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling 0.9634643 1.004
2272 MAP00710_Carbon_fixation_h GenMAPP (external link) H004823_01 Info Aldolase C, fructose-bisphosphate H004823_01 AF054987 (external link) 155247 ALDOC (external link) Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway 0.001576 0.707
2273 MAP00710_Carbon_fixation_h GenMAPP (external link) H003374_01 Info Aldolase A, fructose-bisphosphate H003374_01 M11560 (external link) 273415 ALDOA (external link) Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology 0.0300936 1.252
2274 MAP00710_Carbon_fixation_h GenMAPP (external link) H007138_01 Info Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi H007138_01 S81916 (external link) 169313 Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology 0.0923463 1.164
2275 MAP00710_Carbon_fixation_h GenMAPP (external link) H002872_01 Info Malate dehydrogenase 1, NAD (soluble) H002872_01 D55654 (external link) 75375 MDH1 (external link) Carbon fixation, Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Pyruvate metabolism, Reductive carboxylate cycle (CO2 fixation) 0.2471473 0.895
2276 MAP00710_Carbon_fixation_h GenMAPP (external link) H001847_01 Info Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) H001847_01 M22632 (external link) 170197 GOT2 (external link) Alanine and aspartate metabolism, Alkaloid biosynthesis I, Arginine and proline metabolism, Carbon fixation, Cysteine metabolism, Glutamate metabolism, Novobiocin biosynthesis, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Tyrosine metabolism, immunology 0.287796 0.905
2277 MAP00710_Carbon_fixation_h GenMAPP (external link) H003068_01 Info Pyruvate kinase, muscle H003068_01 M26252 (external link) 198281 PKM2 (external link) Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism 0.3246109 1.102
2278 MAP00710_Carbon_fixation_h GenMAPP (external link) H002150_01 Info Glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) H002150_01 M37400 (external link) 597 GOT1 (external link) Malate-aspartate shuttle, Alanine and aspartate metabolism, Alkaloid biosynthesis I, Arginine and proline metabolism, Carbon fixation, Cysteine metabolism, Glutamate metabolism, Novobiocin biosynthesis, Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Tyrosine metabolism 0.3605272 0.917
2279 MAP00710_Carbon_fixation_h GenMAPP (external link) H001549_01 Info Malate dehydrogenase 2, NAD (mitochondrial) H001549_01 AF047470 (external link) 111076 MDH2 (external link) Malate-aspartate shuttle, Shuttle for transfer of acetyl groups from mitochondria to the cytosol, Carbon fixation, Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Pyruvate metabolism, Reductive carboxylate cycle (CO2 fixation), immunology 0.7163304 0.952
2280 drug_resistance_and_metabolism_h BioCarta H001935_01 Info Glyceraldehyde-3-phosphate dehydrogenase H001935_01 U34995 (external link) 169476 GAPD (external link) 0.0001082 1.485
2281 drug_resistance_and_metabolism_h BioCarta H002040_01 Info Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) H002040_01 X00588 (external link) 77432 EGFR (external link) Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc 0.0004362 0.669
2282 drug_resistance_and_metabolism_h BioCarta H003596_01 Info O-6-methylguanine-DNA methyltransferase H003596_01 M29971 (external link) 1384 MGMT (external link) DNA_adducts, DNA_damage 0.0006291 0.667
2283 drug_resistance_and_metabolism_h BioCarta H003112_01 Info Retinoblastoma 1 (including osteosarcoma) H003112_01 L41870 (external link) 75770 RB1 (external link) BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc 0.0008596 0.674
2284 drug_resistance_and_metabolism_h BioCarta H002412_01 Info Cyclin-dependent kinase 2 H002412_01 M68520 (external link) 19192 CDK2 (external link) CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction 0.0040171 0.711
2285 drug_resistance_and_metabolism_h BioCarta H000872_01 Info ATP-binding cassette, sub-family C (CFTR/MRP), member 5 H000872_01 AF104942 (external link) 108660 ABCC5 (external link) 0.00423 0.773
2286 drug_resistance_and_metabolism_h BioCarta H002387_01 Info MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1) H002387_01 NM_000251 (external link) 78934 MSH2 (external link) DNA_damage, tsonc 0.004273 0.694
2287 drug_resistance_and_metabolism_h BioCarta H000208_01 Info Breast cancer 1, early onset H000208_01 NM_007295 (external link) 194143 BRCA1 (external link) ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc 0.009032 0.746
2288 drug_resistance_and_metabolism_h BioCarta H003606_01 Info Retinoid X receptor, alpha H003606_01 U66306 (external link) 20084 RXRA (external link) Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription 0.0142664 1.308
2289 drug_resistance_and_metabolism_h BioCarta H001848_01 Info Glutathione S-transferase M1 H001848_01 J03817 (external link) 324730 GSTM1 (external link) Glutathione metabolism, immunology, pharmacology 0.018415 0.773

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