Pathway Comparison – Page Two
Table – Significant pathway by running the Hotelling T-square test consists of the following genes (sorted by p-values).
| Broad Pathway | Pathway description | Unique id | Annotations | Description | Clone | GB acc | UG cluster | Gene symbol | Defined gene lists | Parametric p-value | Geometric mean of ratios (class Disease /class Normal ) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | spryPathway_h | BioCarta | H002040_01 | Info | Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) | H002040_01 | X00588 | 77432 | EGFR | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc | 0.0004362 | 0.669 |
| 2 | spryPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 3 | spryPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 4 | spryPathway_h | BioCarta | H002847_01 | Info | Protein tyrosine phosphatase, receptor type, B | H002847_01 | X54131 | 123641 | PTPRB | Sprouty regulation of tyrosine kinase signals, cell_cycle, cell_signaling | 0.0110757 | 1.299 |
| 5 | spryPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 6 | spryPathway_h | BioCarta | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 | 758 | RASA1 | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 7 | spryPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 8 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003352_01 | Info | Interleukin 1 receptor, type I | H003352_01 | M27492 | 82112 | IL1R1 | NF-kB Signaling Pathway, Signal transduction through IL1R, immunology | 0.000502 | 0.677 |
| 9 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 10 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 11 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H000309_01 | Info | CAMP response element-binding protein CRE-BPa | H000309_01 | L05515 | 149 | H_GS165L15.1 | 0.0078273 | 1.479 | |
| 12 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 13 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 14 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003008_01 | Info | Mitogen-activated protein kinase kinase kinase 4 | H003008_01 | AF002715 | 32353 | MAP3K4 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.0127738 | 0.707 |
| 15 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H004258_01 | Info | Elongation factor-2 kinase | H004258_01 | U93850 | 259855 | HSU93850 | Eukaryotic protein translation | 0.0132437 | 0.748 |
| 16 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H011228_01 | Info | G protein-coupled receptor kinase 7 | H011228_01 | AL137615 | 261828 | GPRK7 | Perou’s – Intrinsic – Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.0572981 | 1.27 |
| 17 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003107_01 | Info | Mitogen-activated protein kinase 13 | H003107_01 | AF004709 | 178695 | MAPK13 | Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system | 0.0717244 | 1.171 |
| 18 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H008351_01 | Info | Dual specificity phosphatase 10 | H008351_01 | AB026436 | 177534 | DUSP10 | 0.382916 | 0.922 | |
| 19 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H006851_01 | Info | TAK1-binding protein 2; KIAA0733 protein | H006851_01 | AL117407 | 109727 | KIAA0733 | Toll-Like Receptor Pathway | 0.4908732 | 1.066 |
| 20 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H002340_01 | Info | Mitogen-activated protein kinase kinase kinase 5 | H002340_01 | U67156 | 151988 | MAP3K5 | HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response | 0.5393151 | 1.07 |
| 21 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H002173_01 | Info | Cell division cycle 42 (GTP-binding protein, 25kD) | H002173_01 | AL121735 | 146409 | CDC42 | Agrin in Postsynaptic Differentiation, How does salmonella hijack a cell, p38 MAPK Signaling Pathway , Ras Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, cell_cycle, cell_signaling, signal_transduction | 0.6486191 | 1.035 |
| 22 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 | 71816 | AKT1 | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 23 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H001386_01 | Info | Mitogen-activated protein kinase kinase kinase 10 | H001386_01 | X90846 | 30223 | MAP3K10 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.7007387 | 0.968 |
| 24 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003434_01 | Info | Dual specificity phosphatase 1 | H003434_01 | NM_004417 | 171695 | DUSP1 | CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway | 0.8183145 | 0.968 |
| 25 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 26 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H003163_01 | Info | CAMP responsive element binding protein 1 | H003163_01 | M27691 | 79194 | CREB1 | Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology | 0.9300928 | 1.009 |
| 27 | ST_p38_MAPK_Pathway_h | Signalling Transduction KE | H012856_01 | Info | MAP kinase-interacting serine/threonine kinase 1 | H012856_01 | AB000409 | 5591 | MKNK1 | Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system | 0.9455231 | 0.992 |
| 28 | EMT_UP_h | Jechlinger_et_al_2003 | H003225_01 | Info | Interferon regulatory factor 7 | H003225_01 | AF076494 | 166120 | IRF7 | gene_regulation, transcription | 6.44e-05 | 1.728 |
| 29 | EMT_UP_h | Jechlinger_et_al_2003 | H000825_01 | Info | S100 calcium-binding protein A8 (calgranulin A) | H000825_01 | X06234 | 100000 | S100A8 | immunology | 0.0001788 | 2.746 |
| 30 | EMT_UP_h | Jechlinger_et_al_2003 | H001850_01 | Info | Interferon-stimulated protein, 15 kDa | H001850_01 | M13755 | 833 | ISG15 | 0.0003862 | 1.943 | |
| 31 | EMT_UP_h | Jechlinger_et_al_2003 | H000473_01 | Info | Uridine phosphorylase | H000473_01 | X90858 | 77573 | UP | Pyrimidine metabolism | 0.0005102 | 1.339 |
| 32 | EMT_UP_h | Jechlinger_et_al_2003 | H002726_01 | Info | B-cell CLL/lymphoma 3 | H002726_01 | M31732 | 31210 | BCL3 | tsonc | 0.0147426 | 1.351 |
| 33 | EMT_UP_h | Jechlinger_et_al_2003 | H003466_01 | Info | CD68 antigen | H003466_01 | S57235 | 246381 | CD68 | angiogenesis, immunology, metastasis | 0.0179458 | 1.335 |
| 34 | EMT_UP_h | Jechlinger_et_al_2003 | H003299_01 | Info | Prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | H003299_01 | M59979 | 88474 | PTGS1 | Aspirin Blocks Signaling Pathway Involved in Platelet Activation, Eicosanoid Metabolism, Mechanism of Acetaminophen Activity and Toxicity, Prostaglandin and leukotriene metabolism, immunology | 0.023304 | 0.813 |
| 35 | EMT_UP_h | Jechlinger_et_al_2003 | H003029_01 | Info | Disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein) | H003029_01 | U53446 | 81988 | DAB2 | 0.0291633 | 0.78 | |
| 36 | EMT_UP_h | Jechlinger_et_al_2003 | H003752_01 | Info | Platelet-derived growth factor receptor, beta polypeptide | H003752_01 | J03278 | 76144 | PDGFRB | cell_cycle, cell_signaling, immunology, misc, signal_transduction | 0.0333891 | 0.832 |
| 37 | EMT_UP_h | Jechlinger_et_al_2003 | H006885_01 | Info | Ribonuclease 6 precursor | H006885_01 | NM_003730 | 8297 | RNASE6PL | 0.0955467 | 1.208 | |
| 38 | EMT_UP_h | Jechlinger_et_al_2003 | H000998_01 | Info | Solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | H000998_01 | AB018010 | 79748 | SLC3A2 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.1156436 | 0.843 |
| 39 | EMT_UP_h | Jechlinger_et_al_2003 | H001908_01 | Info | Discoidin domain receptor family, member 2 | H001908_01 | X74764 | 71891 | DDR2 | 0.1167676 | 0.839 | |
| 40 | EMT_UP_h | Jechlinger_et_al_2003 | H001001_01 | Info | Procollagen C-endopeptidase enhancer | H001001_01 | NM_002593 | 202097 | PCOLCE | 0.1228497 | 0.868 | |
| 41 | EMT_UP_h | Jechlinger_et_al_2003 | H000774_01 | Info | Collagen, type VI, alpha 1 | H000774_01 | X15880 | 108885 | COL6A1 | 0.1448402 | 0.841 | |
| 42 | EMT_UP_h | Jechlinger_et_al_2003 | H002775_01 | Info | Platelet-derived growth factor receptor, alpha polypeptide | H002775_01 | M21574 | 74615 | PDGFRA | Perou’s – Intrinsic – Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction | 0.1636921 | 1.107 |
| 43 | EMT_UP_h | Jechlinger_et_al_2003 | H010646_01 | Info | Ribonuclease 6 precursor | H010646_01 | AK001769 | 8297 | RNASE6PL | 0.1872503 | 1.127 | |
| 44 | EMT_UP_h | Jechlinger_et_al_2003 | H002295_01 | Info | Adenosine deaminase | H002295_01 | X02994 | 1217 | ADA | Purine metabolism, gene_regulation, immunology, transcription | 0.1882263 | 0.871 |
| 45 | EMT_UP_h | Jechlinger_et_al_2003 | H012626_01 | Info | Beta-2-microglobulin | H012626_01 | AB021288 | 75415 | B2M | Antigen Processing and Presentation, CTL mediated immune response against target cells , Ras-Independent pathway in NK cell-mediated cytotoxicity, immunology | 0.1923361 | 1.156 |
| 46 | EMT_UP_h | Jechlinger_et_al_2003 | H003645_01 | Info | Interleukin 11 | H003645_01 | X58377 | 1721 | IL11 | Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, Regulation of hematopoiesis by cytokines, immunology | 0.2074062 | 1.116 |
| 47 | EMT_UP_h | Jechlinger_et_al_2003 | H003593_01 | Info | Collagen, type VI, alpha 2 | H003593_01 | AL096746 | 159263 | COL6A2 | 0.300891 | 1.098 | |
| 48 | EMT_UP_h | Jechlinger_et_al_2003 | H001198_01 | Info | Homo sapiens, alpha-1 (VI) collagen | H001198_01 | M20776 | 25459 | 0.3632512 | 1.1 | ||
| 49 | EMT_UP_h | Jechlinger_et_al_2003 | H002451_01 | Info | Flavin containing monooxygenase 1 | H002451_01 | M64082 | 1424 | FMO1 | immunology, misc | 0.3681883 | 0.911 |
| 50 | EMT_UP_h | Jechlinger_et_al_2003 | H000592_01 | Info | Interferon-induced protein with tetratricopeptide repeats 1 | H000592_01 | X03557 | 20315 | IFIT1 | 0.4335751 | 1.121 | |
| 51 | EMT_UP_h | Jechlinger_et_al_2003 | H002713_01 | Info | Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | H002713_01 | U24577 | 93304 | PLA2G7 | Glycerophospholipid metabolism | 0.4631812 | 0.89 |
| 52 | EMT_UP_h | Jechlinger_et_al_2003 | H010497_01 | Info | Interferon induced transmembrane protein 3 (1-8U) | H010497_01 | X57352 | 182241 | IFITM3 | 0.5875785 | 1.062 | |
| 53 | EMT_UP_h | Jechlinger_et_al_2003 | H003695_01 | Info | Secreted protein, acidic, cysteine-rich (osteonectin) | H003695_01 | J03040 | 111779 | SPARC | misc | 0.6414286 | 1.051 |
| 54 | EMT_UP_h | Jechlinger_et_al_2003 | H002330_01 | Info | Cadherin 15, M-cadherin (myotubule) | H002330_01 | D83542 | 148090 | CDH15 | 0.7996949 | 0.974 | |
| 55 | EMT_UP_h | Jechlinger_et_al_2003 | H002397_01 | Info | Methylene tetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase | H002397_01 | X16396 | 154672 | MTHFD2 | Glyoxylate and dicarboxylate metabolism, One carbon pool by folate | 0.8081788 | 0.975 |
| 56 | EMT_UP_h | Jechlinger_et_al_2003 | H002672_01 | Info | G protein-coupled receptor | H002672_01 | U67784 | 23016 | RDC1 | 0.8527585 | 0.967 | |
| 57 | EMT_UP_h | Jechlinger_et_al_2003 | H002490_01 | Info | Hexabrachion (tenascin C, cytotactin) | H002490_01 | X78565 | 289114 | HXB | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.856155 | 0.983 |
| 58 | EMT_UP_h | Jechlinger_et_al_2003 | H002283_01 | Info | Secretory leukocyte protease inhibitor (antileukoproteinase) | H002283_01 | X04470 | 251754 | SLPI | Perou’s – Intrinsic – Breast-Cancer-Genes, Proepithelin Conversion to Epithelin and Wound Repair Control, immunology | 0.9075348 | 1.012 |
| 59 | EMT_UP_h | Jechlinger_et_al_2003 | H004245_01 | Info | Snail 1 (drosophila homolog), zinc finger protein | H004245_01 | AF125377 | 48029 | SNAI1 | Downregulated of MTA-3 in ER-negative Breast Tumors | 0.9743253 | 1.003 |
| 60 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H002040_01 | Info | Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) | H002040_01 | X00588 | 77432 | EGFR | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc | 0.0004362 | 0.669 |
| 61 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 62 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 63 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 64 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 65 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 | 77202 | PRKCB1 | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 66 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 67 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 | 758 | RASA1 | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 68 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 69 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H001349_01 | Info | Janus kinase 1 (a protein tyrosine kinase) | H001349_01 | M64174 | 50651 | JAK1 | EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.2754104 | 1.129 |
| 70 | egfPathway_h | The epidermal growth factor (EGF) peptide stimulates the EGF receptor to promote cell proliferation via the MAP kinase and Ras pathways. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 71 | insulinPathway_h | BioCarta | H000732_01 | Info | Insulin receptor substrate 1 | H000732_01 | S62539 | 96063 | IRS1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology | 0.0013348 | 0.643 |
| 72 | insulinPathway_h | BioCarta | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 73 | insulinPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 74 | insulinPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 75 | insulinPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 76 | insulinPathway_h | BioCarta | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 | 758 | RASA1 | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 77 | insulinPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 78 | insulinPathway_h | BioCarta | H002624_01 | Info | Insulin receptor | H002624_01 | X02160 | 89695 | INSR | Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology | 0.433218 | 0.919 |
| 79 | insulinPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 80 | igf1Pathway_h | BioCarta | H000732_01 | Info | Insulin receptor substrate 1 | H000732_01 | S62539 | 96063 | IRS1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology | 0.0013348 | 0.643 |
| 81 | igf1Pathway_h | BioCarta | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 82 | igf1Pathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 83 | igf1Pathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 84 | igf1Pathway_h | BioCarta | H002473_01 | Info | Insulin-like growth factor 1 receptor | H002473_01 | NM_000875 | 239176 | IGF1R | Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology | 0.079692 | 1.158 |
| 85 | igf1Pathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 86 | igf1Pathway_h | BioCarta | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 | 758 | RASA1 | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 87 | igf1Pathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 88 | igf1Pathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 89 | il6Pathway_h | BioCarta | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 90 | il6Pathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 91 | il6Pathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 92 | il6Pathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 93 | il6Pathway_h | BioCarta | H001349_01 | Info | Janus kinase 1 (a protein tyrosine kinase) | H001349_01 | M64174 | 50651 | JAK1 | EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.2754104 | 1.129 |
| 94 | il6Pathway_h | BioCarta | H002824_01 | Info | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | H002824_01 | U09607 | 99877 | JAK3 | IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.4735774 | 1.051 |
| 95 | il6Pathway_h | BioCarta | H008390_01 | Info | Homo sapiens mRNA; cDNA DKFZp564F053 (from clone DKFZp564F053) | H008390_01 | AL049265 | 71968 | immunology | 0.6157756 | 1.05 | |
| 96 | il6Pathway_h | BioCarta | H003110_01 | Info | Interleukin 6 (interferon, beta 2) | H003110_01 | X04430 | 93913 | IL6 | Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology | 0.680804 | 1.036 |
| 97 | il6Pathway_h | BioCarta | H003456_01 | Info | Interleukin 6 receptor | H003456_01 | X12830 | 193400 | IL6R | IL 6 signaling pathway, Role of ERBB2 in Signal Transduction and Oncology, immunology | 0.7143407 | 1.03 |
| 98 | il6Pathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 99 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003000_01 | Info | RAB5A, member RAS oncogene family | H003000_01 | M28215 | 73957 | RAB5A | Phosphoinositides and their downstream targets., Rab GTPases Mark Targets In The Endocytotic Machinery, The role of FYVE-finger proteins in vesicle transport, tsonc | 0.0003278 | 0.591 |
| 100 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003112_01 | Info | Retinoblastoma 1 (including osteosarcoma) | H003112_01 | L41870 | 75770 | RB1 | BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0008596 | 0.674 |
| 101 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001800_01 | Info | Proteasome (prosome, macropain) subunit, alpha type, 5 | H001800_01 | X61970 | 76913 | PSMA5 | Proteasome | 0.00104 | 0.69 |
| 102 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003760_01 | Info | DnaJ (Hsp40) homolog, subfamily A, member 1 | H003760_01 | L08069 | 94 | DNAJA1 | 0.0016053 | 0.695 | |
| 103 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H007996_01 | Info | GABA(A) receptor-associated protein | H007996_01 | NM_007278 | 7719 | GABARAP | Gamma-aminobutyric Acid Receptor Life Cycle | 0.0021636 | 1.497 |
| 104 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001791_01 | Info | Ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | H001791_01 | X04741 | 76118 | UCHL1 | 0.002493 | 0.711 | |
| 105 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002387_01 | Info | MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1) | H002387_01 | NM_000251 | 78934 | MSH2 | DNA_damage, tsonc | 0.004273 | 0.694 |
| 106 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H006293_01 | Info | ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD | H006293_01 | D89052 | 7476 | ATP6F | Perou’s – Intrinsic – Breast-Cancer-Genes, ATP synthesis, Oxidative phosphorylation | 0.0071282 | 1.372 |
| 107 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000152_01 | Info | Kinesin-like 1 | H000152_01 | U37426 | 8878 | KNSL1 | 0.0084868 | 0.761 | |
| 108 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H011911_01 | Info | KIAA0594 protein | H011911_01 | AB011166 | 103283 | KIAA0594 | 0.0129673 | 1.228 | |
| 109 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001903_01 | Info | Polymerase (DNA directed), gamma | H001903_01 | X98093 | 80961 | POLG | DNA polymerase, Purine metabolism, Pyrimidine metabolism | 0.0148856 | 0.783 |
| 110 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H007126_01 | Info | Mouse Mammary Turmor Virus Receptor homolog | H007126_01 | AF052151 | 18686 | MTVR | 0.0175107 | 1.245 | |
| 111 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003739_01 | Info | Cell division cycle 2, G1 to S and G2 to M | H003739_01 | X05360 | 184572 | CDC2 | Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Protein Kinase A at the Centrosome, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of Splicing through Sam68, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system, cell_cycle | 0.0222229 | 0.733 |
| 112 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012105_01 | Info | Testis enhanced gene transcript (BAX inhibitor 1) | H012105_01 | X75861 | 74637 | TEGT | transcription | 0.0238861 | 1.237 |
| 113 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001391_01 | Info | KIAA1093 protein | H001391_01 | AB029016 | 117333 | KIAA1093 | 0.0266235 | 1.238 | |
| 114 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H007917_01 | Info | Translation factor sui1 homolog | H007917_01 | NM_005875 | 21756 | GC20 | 0.0373086 | 1.222 | |
| 115 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001311_01 | Info | ATP/GTP-binding protein | H001311_01 | U73524 | 87465 | HEAB | 0.0452149 | 0.788 | |
| 116 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003973_01 | Info | EH domain containing 1 | H003973_01 | NM_006795 | 155119 | EHD1 | 0.0507649 | 1.257 | |
| 117 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000449_01 | Info | Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4 | H000449_01 | AF011466 | 122575 | EDG4 | 0.0524489 | 1.347 | |
| 118 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003719_01 | Info | Integrin, beta 7 | H003719_01 | M68892 | 1741 | ITGB7 | cell_signaling, immunology, metastasis | 0.0529984 | 0.815 |
| 119 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001798_01 | Info | Ubiquitin specific protease 12 | H001798_01 | AF022789 | 42400 | USP12 | 0.0549997 | 1.187 | |
| 120 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000564_01 | Info | Protein kinase C binding protein 1 | H000564_01 | AB032951 | 75871 | PRKCBP1 | 0.0986503 | 0.835 | |
| 121 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002491_01 | Info | Bone morphogenetic protein 1 | H002491_01 | NM_006129 | 1274 | BMP1 | development | 0.1079128 | 0.821 |
| 122 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002928_01 | Info | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | H002928_01 | X69398 | 82685 | CD47 | Perou’s – Intrinsic – Breast-Cancer-Genes, angiogenesis, cell_signaling, immunology, metastasis | 0.11106 | 0.854 |
| 123 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012158_01 | Info | Upregulated by 1,25-dihydroxyvitamin D-3 | H012158_01 | S73591 | 179526 | VDUP1 | 0.1293789 | 1.193 | |
| 124 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003050_01 | Info | Chaperonin containing TCP1, subunit 4 (delta) | H003050_01 | AF026291 | 79150 | CCT4 | B Cell Survival Pathway | 0.1325252 | 1.126 |
| 125 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001622_01 | Info | RAB31, member RAS oncogene family | H001622_01 | U59877 | 223025 | RAB31 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.152499 | 1.183 |
| 126 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002970_01 | Info | Integrin-linked kinase | H002970_01 | U40282 | 6196 | ILK | PTEN dependent cell cycle arrest and apoptosis, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.1701136 | 1.128 |
| 127 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002365_01 | Info | Activated p21cdc42Hs kinase | H002365_01 | L13738 | 153937 | ACK1 | 0.173678 | 1.162 | |
| 128 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000644_01 | Info | Protein phosphatase 2, regulatory subunit B (B56), alpha isoform | H000644_01 | L42373 | 155079 | PPP2R5A | cell_cycle, cell_signaling, signal_transduction | 0.1872145 | 0.884 |
| 129 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H009793_01 | Info | Rac/Cdc42 guanine exchange factor (GEF) 6 | H009793_01 | D25304 | 79307 | ARHGEF6 | Agrin in Postsynaptic Differentiation | 0.2184793 | 1.139 |
| 130 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001256_01 | Info | Sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase) | H001256_01 | X74570 | 75268 | SIAT4C | 0.2276302 | 0.892 | |
| 131 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H009783_01 | Info | KIAA0281 gene product | H009783_01 | D87457 | 31463 | KIAA0281 | 0.2322521 | 1.152 | |
| 132 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002298_01 | Info | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break | H002298_01 | M30938 | 84981 | XRCC5 | Telomeres, Telomerase, Cellular Aging, and Immortality, DNA_damage, DNA_replication | 0.2435454 | 1.101 |
| 133 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H010810_01 | Info | Splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) | H010810_01 | M72709 | 73737 | SFRS1 | 0.2552533 | 0.909 | |
| 134 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H011501_01 | Info | ADP-ribosylation factor 4 | H011501_01 | NM_001660 | 75290 | ARF4 | 0.2579932 | 0.884 | |
| 135 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001876_01 | Info | 3′-phosphoadenosine 5′-phosphosulfate synthase 1 | H001876_01 | AF105227 | 3833 | PAPSS1 | Purine metabolism, Selenoamino acid metabolism, Sulfur metabolism | 0.2713835 | 0.89 |
| 136 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008985_01 | Info | Eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) | H008985_01 | U54559 | 58189 | EIF3S3 | 0.2852233 | 0.906 | |
| 137 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001270_01 | Info | Interferon, gamma-inducible protein 16 | H001270_01 | M63838 | 155530 | IFI16 | cell_signaling | 0.2909837 | 1.116 |
| 138 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002973_01 | Info | RAB1, member RAS oncogene family | H002973_01 | M28209 | 3642 | RAB1 | Rab GTPases Mark Targets In The Endocytotic Machinery | 0.292711 | 1.103 |
| 139 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003828_01 | Info | Retinoblastoma-binding protein 4 | H003828_01 | X74262 | 16003 | RBBP4 | Mechanisms of transcriptional repression by DNA methylation, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails | 0.3028553 | 0.925 |
| 140 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002889_01 | Info | Cyclin G1 | H002889_01 | X77794 | 79101 | CCNG1 | 0.3030012 | 0.898 | |
| 141 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003933_01 | Info | General transcription factor IIA, 2 (12kD subunit) | H003933_01 | U14193 | 76362 | GTF2A2 | 0.3056055 | 0.899 | |
| 142 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H009033_01 | Info | Neuromedin U | H009033_01 | X76029 | 2841 | NMU | 0.3059932 | 1.152 | |
| 143 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001344_01 | Info | Fusion, derived from t(12;16) malignant liposarcoma | H001344_01 | S62140 | 99969 | FUS | misc | 0.3107752 | 0.912 |
| 144 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012325_01 | Info | Extra spindle poles, S. cerevisiae, homolog of | H012325_01 | D79987 | 153479 | KIAA0165 | 0.3223766 | 1.126 | |
| 145 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008280_01 | Info | Era (E. coli G-protein homolog)-like 1 | H008280_01 | AF082657 | 3426 | ERAL1 | 0.326229 | 1.083 | |
| 146 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001406_01 | Info | Huntingtin interacting protein-1-related | H001406_01 | AB014555 | 96731 | KIAA0655 | 0.3265079 | 0.911 | |
| 147 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000325_01 | Info | Nuclear transcription factor Y, beta | H000325_01 | X59710 | 84928 | NFYB | Overview of telomerase RNA component gene hTerc Transcriptional Regulation | 0.3282461 | 0.893 |
| 148 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002715_01 | Info | Prohibitin | H002715_01 | NM_002634 | 75323 | PHB | immunology | 0.3408704 | 0.898 |
| 149 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000723_01 | Info | Angio-associated, migratory cell protein | H000723_01 | M95627 | 83347 | AAMP | 0.3859087 | 0.934 | |
| 150 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002782_01 | Info | Wee1+ (S. pombe) homolog | H002782_01 | X62048 | 75188 | WEE1 | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology | 0.4033875 | 1.142 |
| 151 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012030_01 | Info | Chromosome 1 open reading frame 8 | H012030_01 | AF047439 | 11441 | C1ORF8 | 0.424321 | 0.929 | |
| 152 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001314_01 | Info | DEK oncogene (DNA binding) | H001314_01 | X64229 | 110713 | DEK | 0.4424083 | 0.934 | |
| 153 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008388_01 | Info | Melanoma antigen, family D, 1 | H008388_01 | NM_006986 | 177556 | MAGED1 | 0.4445493 | 0.9 | |
| 154 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002127_01 | Info | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | H002127_01 | D86550 | 75842 | DYRK1A | Sonic Hedgehog (Shh) Pathway | 0.4628734 | 0.926 |
| 155 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008179_01 | Info | PTD017 protein | H008179_01 | AL050361 | 274417 | PTD017 | 0.5042695 | 1.068 | |
| 156 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H013411_01 | Info | Ribosomal protein, large P2 | H013411_01 | M17887 | 119500 | RPLP2 | 0.5256547 | 1.063 | |
| 157 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H010641_01 | Info | Bromodomain adjacent to zinc finger domain, 1A | H010641_01 | AB032252 | 8858 | BAZ1A | 0.5315479 | 1.065 | |
| 158 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H011767_01 | Info | SH2-B homolog | H011767_01 | AB037720 | 15744 | DKFZP547G1110 | 0.5793807 | 1.053 | |
| 159 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008484_01 | Info | Heterogeneous nuclear ribonucleoprotein R | H008484_01 | AF000364 | 15265 | HNRPR | 0.5936826 | 1.065 | |
| 160 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001516_01 | Info | Guanosine monophosphate reductase | H001516_01 | M24470 | 1435 | GMPR | Purine metabolism | 0.5998588 | 0.932 |
| 161 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001288_01 | Info | ELL gene (11-19 lysine-rich leukemia gene) | H001288_01 | U16282 | 5881 | ELL | 0.6032943 | 1.082 | |
| 162 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001304_01 | Info | ALL1-fused gene from chromosome 1q | H001304_01 | U16954 | 75823 | AF1Q | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.603919 | 1.053 |
| 163 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012106_01 | Info | Src-like-adapter | H012106_01 | D89077 | 75367 | SLA | 0.6044071 | 0.939 | |
| 164 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002217_01 | Info | Dishevelled 3 (homologous to Drosophila dsh) | H002217_01 | NM_004423 | 174044 | DVL3 | cell_signaling, signal_transduction | 0.6065023 | 1.058 |
| 165 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H011167_01 | Info | HSPC035 protein | H011167_01 | NM_016127 | 279921 | LOC51669 | 0.6199261 | 1.046 | |
| 166 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H011548_01 | Info | Fzr1 protein | H011548_01 | AB033068 | 268384 | FZR1 | 0.6646964 | 1.035 | |
| 167 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002527_01 | Info | Replication protein A3 (14kD) | H002527_01 | L07493 | 1608 | RPA3 | DNA_replication | 0.6875779 | 0.952 |
| 168 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000388_01 | Info | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | H000388_01 | AL110183 | 73851 | ATP5J | ATP synthesis, Oxidative phosphorylation, misc | 0.7600099 | 0.953 |
| 169 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H010946_01 | Info | Artemin | H010946_01 | AF109401 | 194689 | ARTN | 0.7609159 | 1.05 | |
| 170 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H009706_01 | Info | RAB1, member RAS oncogene family | H009706_01 | AL050268 | 3642 | RAB1 | Rab GTPases Mark Targets In The Endocytotic Machinery | 0.7686339 | 0.971 |
| 171 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003482_01 | Info | Catechol-O-methyltransferase | H003482_01 | NM_000754 | 240013 | COMT | Tyrosine metabolism, behavior, immunology | 0.777803 | 1.026 |
| 172 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H011214_01 | Info | Williams-Beuren syndrome chromosome region 1 | H011214_01 | D26068 | 180900 | WBSCR1 | 0.7785992 | 0.975 | |
| 173 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012850_01 | Info | Nucleosome assembly protein 1-like 1 | H012850_01 | AL162068 | 179662 | NAP1L1 | 0.7805775 | 0.973 | |
| 174 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H007376_01 | Info | Homo sapiens cDNA: FLJ22071 fis, clone HEP11691 | H007376_01 | AL049932 | 326248 | 0.785212 | 1.026 | ||
| 175 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H007641_01 | Info | Solute carrier family 12 (potassium/chloride transporters), member 4 | H007641_01 | AF054506 | 10094 | SLC12A4 | 0.7951601 | 1.026 | |
| 176 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001333_01 | Info | Phosphatidylinositol binding clathrin assembly protein | H001333_01 | U45976 | 7885 | PICALM | Endocytotic role of NDK, Phosphins and Dynamin | 0.8121842 | 0.978 |
| 177 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008039_01 | Info | DnaJ (Hsp40) homolog, subfamily B, member 6 | H008039_01 | AB015798 | 181195 | DNAJB6 | Prion Pathway | 0.8136927 | 1.024 |
| 178 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H008319_01 | Info | KIAA0461 protein | H008319_01 | AB007930 | 107088 | KIAA0461 | 0.8286286 | 1.017 | |
| 179 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H003056_01 | Info | FOS-like antigen 2 | H003056_01 | X16706 | 301612 | FOSL2 | Bone Remodelling, tsonc | 0.85065 | 1.018 |
| 180 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012188_01 | Info | E2F transcription factor 4, p107/p130-binding | H012188_01 | S75174 | 108371 | E2F4 | METS affect on Macrophage Differentiation | 0.8845118 | 0.986 |
| 181 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000641_01 | Info | Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | H000641_01 | J02683 | 79172 | SLC25A5 | 0.8966066 | 1.014 | |
| 182 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H012177_01 | Info | SEC24 (S. cerevisiae) related gene family, member C | H012177_01 | D38555 | 81964 | SEC24C | 0.9009444 | 0.987 | |
| 183 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H000555_01 | Info | MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 | H000555_01 | U65410 | 79078 | MAD2L1 | cell_cycle | 0.9117596 | 1.012 |
| 184 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H010542_01 | Info | M-phase phosphoprotein homolog | H010542_01 | NM_016107 | 173518 | LOC51663 | 0.9533604 | 0.995 | |
| 185 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H001079_01 | Info | Sodium channel, voltage-gated, type IV, alpha polypeptide | H001079_01 | M81758 | 46038 | SCN4A | immunology | 0.9599901 | 1.005 |
| 186 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H004613_01 | Info | Telomeric repeat binding factor 2 | H004613_01 | AF002999 | 100030 | TERF2 | immunology | 0.9802633 | 0.997 |
| 187 | GLUCOSE_DOWN_h | Peng_et_al_2002 | H002746_01 | Info | TNF receptor-associated factor 5 | H002746_01 | AB000509 | 29736 | TRAF5 | TACI and BCMA stimulation of B cell immune responses., immunology | 0.9871372 | 0.999 |
| 188 | ghPathway_h | BioCarta | H000732_01 | Info | Insulin receptor substrate 1 | H000732_01 | S62539 | 96063 | IRS1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology | 0.0013348 | 0.643 |
| 189 | ghPathway_h | BioCarta | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 190 | ghPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 191 | ghPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 192 | ghPathway_h | BioCarta | H002890_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 1 | H002890_01 | L07597 | 149957 | RPS6KA1 | Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system | 0.0138896 | 1.42 |
| 193 | ghPathway_h | BioCarta | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 | 77202 | PRKCB1 | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 194 | ghPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 195 | ghPathway_h | BioCarta | H002624_01 | Info | Insulin receptor | H002624_01 | X02160 | 89695 | INSR | Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Growth Hormone Signaling Pathway, Insulin Signaling Pathway, immunology | 0.433218 | 0.919 |
| 196 | ghPathway_h | BioCarta | H002261_01 | Info | Signal transducer and activator of transcription 5B | H002261_01 | U47686 | 244613 | STAT5B | 0.441402 | 1.071 | |
| 197 | ghPathway_h | BioCarta | H009068_01 | Info | Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) | H009068_01 | AL080218 | 24064 | 0.509279 | 1.056 | ||
| 198 | ghPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 199 | il2rbPathway_h | BioCarta | H000732_01 | Info | Insulin receptor substrate 1 | H000732_01 | S62539 | 96063 | IRS1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology | 0.0013348 | 0.643 |
| 200 | il2rbPathway_h | BioCarta | H000600_01 | Info | STAT induced STAT inhibitor 3 | H000600_01 | AB004904 | 296176 | SSI-3 | IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway | 0.0013931 | 0.69 |
| 201 | il2rbPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 202 | il2rbPathway_h | BioCarta | H000438_01 | Info | CASP8 and FADD-like apoptosis regulator | H000438_01 | Y14039 | 195175 | CFLAR | FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, IL-2 Receptor Beta Chain in T cell Activation, Induction of apoptosis through DR3 and DR4/5 Death Receptors | 0.00266 | 1.745 |
| 203 | il2rbPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 204 | il2rbPathway_h | BioCarta | H003332_01 | Info | V-crk avian sarcoma virus CT10 oncogene homolog-like | H003332_01 | X59656 | 37078 | CRKL | IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc | 0.0164206 | 0.675 |
| 205 | il2rbPathway_h | BioCarta | H003305_01 | Info | Ribosomal protein S6 kinase, 70kD, polypeptide 1 | H003305_01 | M60724 | 86858 | RPS6KB1 | CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0214523 | 1.448 |
| 206 | il2rbPathway_h | BioCarta | H003718_01 | Info | Interleukin 2 receptor, gamma (severe combined immunodeficiency) | H003718_01 | D11086 | 84 | IL2RG | IL 2 signaling pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, immunology | 0.0314631 | 1.258 |
| 207 | il2rbPathway_h | BioCarta | H013244_01 | Info | N-myc (and STAT) interactor | H013244_01 | U32849 | 54483 | NMI | IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, signal_transduction | 0.0799702 | 1.269 |
| 208 | il2rbPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 209 | il2rbPathway_h | BioCarta | H014546_01 | Info | Peptidylprolyl isomerase A (cyclophilin A) | H014546_01 | NM_021130 | 182937 | PPIA | IL-2 Receptor Beta Chain in T cell Activation | 0.129858 | 1.176 |
| 210 | il2rbPathway_h | BioCarta | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 | 79070 | MYC | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 211 | il2rbPathway_h | BioCarta | H003042_01 | Info | BCL2-like 1 | H003042_01 | Z23115 | 305890 | BCL2L1 | Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology | 0.2336065 | 1.143 |
| 212 | il2rbPathway_h | BioCarta | H001349_01 | Info | Janus kinase 1 (a protein tyrosine kinase) | H001349_01 | M64174 | 50651 | JAK1 | EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.2754104 | 1.129 |
| 213 | il2rbPathway_h | BioCarta | H002261_01 | Info | Signal transducer and activator of transcription 5B | H002261_01 | U47686 | 244613 | STAT5B | 0.441402 | 1.071 | |
| 214 | il2rbPathway_h | BioCarta | H003644_01 | Info | Tumor necrosis factor receptor superfamily, member 6 | H003644_01 | X63717 | 82359 | TNFRSF6 | apoptosis, immunology | 0.4621499 | 0.927 |
| 215 | il2rbPathway_h | BioCarta | H002824_01 | Info | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | H002824_01 | U09607 | 99877 | JAK3 | IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.4735774 | 1.051 |
| 216 | il2rbPathway_h | BioCarta | H009068_01 | Info | Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) | H009068_01 | AL080218 | 24064 | 0.509279 | 1.056 | ||
| 217 | il2rbPathway_h | BioCarta | H003650_01 | Info | Interleukin 2 receptor, alpha | H003650_01 | X01057 | 1724 | IL2RA | IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology | 0.5932248 | 1.054 |
| 218 | il2rbPathway_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 | 71816 | AKT1 | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 219 | il2rbPathway_h | BioCarta | H001974_01 | Info | BCL2-antagonist of cell death | H001974_01 | U66879 | 76366 | BAD | AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development | 0.6985187 | 0.954 |
| 220 | il2rbPathway_h | BioCarta | H015889_01 | Info | BCL2-like 1 | H015889_01 | NM_001191 | 305890 | BCL2L1 | Apoptotic Signaling in Response to DNA Damage, IL-2 Receptor Beta Chain in T cell Activation, Opposing roles of AIF in Apoptosis and Cell Survival, Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, immunology | 0.996743 | 1.001 |
| 221 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H001032_01 | Info | Cytotoxic T-lymphocyte-associated protein 4 | H001032_01 | L15006 | 247824 | CTLA4 | The Co-Stimulatory Signal During T-cell Activation, immunology | 0.0001134 | 0.56 |
| 222 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H008261_01 | Info | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | H008261_01 | Y12336 | 99491 | RASGRP2 | 0.0002126 | 1.594 | |
| 223 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 224 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 225 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003628_01 | Info | Dystroglycan 1 (dystrophin-associated glycoprotein 1) | H003628_01 | L19711 | 76111 | DAG1 | Agrin in Postsynaptic Differentiation, immunology | 0.034627 | 0.774 |
| 226 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003212_01 | Info | Zeta-chain (TCR) associated protein kinase (70 kD) | H003212_01 | L05148 | 234569 | ZAP70 | Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, cell_cycle, cell_signaling, signal_transduction | 0.0970422 | 0.833 |
| 227 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 228 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H001748_01 | Info | Inositol 1,4,5-trisphosphate 3-kinase B | H001748_01 | X57206 | 78877 | ITPKB | Inositol phosphate metabolism, Phosphatidylinositol signaling system, cell_signaling, signal_transduction | 0.1283627 | 0.851 |
| 229 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H001718_01 | Info | Inositol 1,4,5-trisphosphate 3-kinase A | H001718_01 | X54938 | 2722 | ITPKA | Inositol phosphate metabolism, Phosphatidylinositol signaling system | 0.1331494 | 1.16 |
| 230 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003550_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | H003550_01 | S76638 | 73090 | NFKB2 | gene_regulation, immunology, transcription, tsonc | 0.1593331 | 1.165 |
| 231 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H011731_01 | Info | P21 (CDKN1A)-activated kinase 3 | H011731_01 | AF068864 | 152663 | PAK3 | Phosphatidylinositol signaling system | 0.1960548 | 1.141 |
| 232 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003820_01 | Info | Lymphocyte-specific protein tyrosine kinase | H003820_01 | X05027 | 1765 | LCK | Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, IL 2 signaling pathway, IL-7 Signal Transduction, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cell Receptor Signaling Pathway, The Co-Stimulatory Signal During T-cell Activation, immunology, signal_transduction, tsonc | 0.2266863 | 0.873 |
| 233 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H000543_01 | Info | Linker for activation of T cells | H000543_01 | AJ223280 | 83496 | LAT | Ras-Independent pathway in NK cell-mediated cytotoxicity, T Cell Receptor Signaling Pathway | 0.354745 | 0.903 |
| 234 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H013901_01 | Info | Protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs | H013901_01 | AB032968 | 20447 | PAK4 | Phosphatidylinositol signaling system | 0.3636917 | 0.913 |
| 235 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H012554_01 | Info | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | H012554_01 | AF081195 | 182591 | RASGRP1 | 0.3661482 | 0.901 | |
| 236 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H015286_01 | Info | Homo sapiens PAK2 mRNA, complete CDS | H015286_01 | AF092132 | 284275 | FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAP Kinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system | 0.4868167 | 1.068 | |
| 237 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H008413_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | H008413_01 | X77909 | 2764 | NFKBIL1 | 0.5281661 | 1.058 | |
| 238 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H002812_01 | Info | Protein tyrosine phosphatase, receptor type, C | H002812_01 | Y00062 | 170121 | PTPRC | Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology | 0.6066202 | 1.093 |
| 239 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003651_01 | Info | EphB2 | H003651_01 | AF025304 | 125124 | EPHB2 | development | 0.7855294 | 0.971 |
| 240 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H002447_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | H002447_01 | M69043 | 81328 | NFKBIA | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … | 0.8245205 | 0.975 |
| 241 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H012662_01 | Info | Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954 | H012662_01 | AK001067 | 6226 | 0.8484663 | 1.017 | ||
| 242 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 243 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H001340_01 | Info | Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) | H001340_01 | U20158 | 2488 | LCP2 | immunology | 0.9191876 | 1.009 |
| 244 | ST_T_Cell_Signal_Transduction_h | Signalling Transduction KE | H003340_01 | Info | C-src tyrosine kinase | H003340_01 | X60114 | 77793 | CSK | Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Activation of Src by Protein-tyrosine phosphatase alpha, Cell to Cell Adhesion Signaling, Integrin Signaling Pathway, signal_transduction | 0.9390319 | 1.008 |
| 245 | pdgfPathway_h | BioCarta | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 246 | pdgfPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 247 | pdgfPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 248 | pdgfPathway_h | BioCarta | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 249 | pdgfPathway_h | BioCarta | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 | 77202 | PRKCB1 | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 250 | pdgfPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 251 | pdgfPathway_h | BioCarta | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 | 758 | RASA1 | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 252 | pdgfPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 253 | pdgfPathway_h | BioCarta | H002775_01 | Info | Platelet-derived growth factor receptor, alpha polypeptide | H002775_01 | M21574 | 74615 | PDGFRA | Perou’s – Intrinsic – Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction | 0.1636921 | 1.107 |
| 254 | pdgfPathway_h | BioCarta | H001349_01 | Info | Janus kinase 1 (a protein tyrosine kinase) | H001349_01 | M64174 | 50651 | JAK1 | EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.2754104 | 1.129 |
| 255 | pdgfPathway_h | BioCarta | H003231_01 | Info | Platelet-derived growth factor alpha polypeptide | H003231_01 | X06374 | 37040 | PDGFA | Cytokines and Inflammatory Response, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), PDGF Signaling Pathway, Phospholipids as signaling intermediaries, immunology, misc, signal_transduction | 0.6989894 | 1.039 |
| 256 | pdgfPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 257 | igf1rPathway_h | BioCarta | H000732_01 | Info | Insulin receptor substrate 1 | H000732_01 | S62539 | 96063 | IRS1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology | 0.0013348 | 0.643 |
| 258 | igf1rPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 259 | igf1rPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 260 | igf1rPathway_h | BioCarta | H002473_01 | Info | Insulin-like growth factor 1 receptor | H002473_01 | NM_000875 | 239176 | IGF1R | Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology | 0.079692 | 1.158 |
| 261 | igf1rPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 262 | igf1rPathway_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 | 71816 | AKT1 | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 263 | igf1rPathway_h | BioCarta | H001974_01 | Info | BCL2-antagonist of cell death | H001974_01 | U66879 | 76366 | BAD | AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development | 0.6985187 | 0.954 |
| 264 | igf1rPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 265 | MAPK_Cascade_h | GO | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 266 | MAPK_Cascade_h | GO | H001648_01 | Info | Myelin basic protein | H001648_01 | M13577 | 69547 | MBP | 0.0014651 | 0.667 | |
| 267 | MAPK_Cascade_h | GO | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 268 | MAPK_Cascade_h | GO | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 269 | MAPK_Cascade_h | GO | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 270 | MAPK_Cascade_h | GO | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 271 | MAPK_Cascade_h | GO | H000029_01 | Info | Mitogen-activated protein kinase kinase kinase 3 | H000029_01 | U78876 | 29282 | MAP3K3 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.2027051 | 1.138 |
| 272 | MAPK_Cascade_h | GO | H002943_01 | Info | V-raf murine sarcoma viral oncogene homolog B1 | H002943_01 | M95712 | 622 | BRAF | MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc | 0.2376595 | 0.895 |
| 273 | MAPK_Cascade_h | GO | H003309_01 | Info | Mitogen-activated protein kinase kinase 7 | H003309_01 | AF013589 | 110299 | MAP2K7 | Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway | 0.3044184 | 1.088 |
| 274 | MAPK_Cascade_h | GO | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 275 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H002038_01 | Info | Flavin containing monooxygenase 5 | H002038_01 | Z47553 | 14286 | FMO5 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.0001007 | 1.877 |
| 276 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003352_01 | Info | Interleukin 1 receptor, type I | H003352_01 | M27492 | 82112 | IL1R1 | NF-kB Signaling Pathway, Signal transduction through IL1R, immunology | 0.000502 | 0.677 |
| 277 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H000872_01 | Info | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | H000872_01 | AF104942 | 108660 | ABCC5 | 0.00423 | 0.773 | |
| 278 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H015306_01 | Info | Core promoter element binding protein | H015306_01 | NM_001300 | 285313 | COPEB | 0.0052134 | 1.473 | |
| 279 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H000896_01 | Info | Stanniocalcin 1 | H000896_01 | U25997 | 25590 | STC1 | 0.0071618 | 0.726 | |
| 280 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H001508_01 | Info | Aldehyde dehydrogenase 4 family, member A1 | H001508_01 | U24266 | 77448 | ALDH4A1 | Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline, Arginine and proline metabolism, Glutamate metabolism | 0.0262657 | 0.769 |
| 281 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H002243_01 | Info | Ras homolog gene family, member E | H002243_01 | S82240 | 6838 | ARHE | immunology | 0.032366 | 1.421 |
| 282 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003570_01 | Info | Annexin A3 | H003570_01 | M20560 | 1378 | ANXA3 | 0.049571 | 1.236 | |
| 283 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H002515_01 | Info | Clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed pro | H002515_01 | M25915 | 75106 | CLU | Perou’s – Intrinsic – Breast-Cancer-Genes, immunology | 0.0769494 | 0.829 |
| 284 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H001717_01 | Info | RAP1, GTPase activating protein 1 | H001717_01 | M64788 | 75151 | RAP1GA1 | 0.0888214 | 1.197 | |
| 285 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H015322_01 | Info | CD24 antigen (small cell lung carcinoma cluster 4 antigen) | H015322_01 | NM_013230 | 286124 | CD24 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.0961671 | 1.127 |
| 286 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H007609_01 | Info | Protein phosphatase 1, regulatory (inhibitor) subunit 5 | H007609_01 | Y18207 | 303090 | PPP1R5 | 0.1045358 | 1.172 | |
| 287 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H015668_01 | Info | Parvalbumin | H015668_01 | NM_002854 | 295449 | PVALB | 0.153268 | 0.857 | |
| 288 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H009511_01 | Info | Melanoma associated gene | H009511_01 | D86983 | 118893 | D2S448 | 0.1767501 | 0.81 | |
| 289 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H008648_01 | Info | Selenium binding protein 1 | H008648_01 | U29091 | 288973 | SELENBP1 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.2017613 | 1.203 |
| 290 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H001905_01 | Info | LPS-induced TNF-alpha factor | H001905_01 | NM_004862 | 76507 | PIG7 | 0.2026162 | 1.209 | |
| 291 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003391_01 | Info | Laminin, beta 1 | H003391_01 | NM_002291 | 82124 | LAMB1 | Prion Pathway | 0.2163833 | 0.846 |
| 292 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H000262_01 | Info | KIAA0307 gene product | H000262_01 | AB002305 | 6111 | KIAA0307 | 0.2604448 | 0.889 | |
| 293 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H007445_01 | Info | Homo sapiens cDNA FLJ20153 fis, clone COL08656, highly similar to AJ001381 Homo sapiens incomplete c | H007445_01 | AK000160 | 121576 | 0.2652388 | 0.847 | ||
| 294 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H000651_01 | Info | Mad4 homolog | H000651_01 | AF040963 | 102402 | MAD4 | 0.266447 | 0.891 | |
| 295 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H000502_01 | Info | Phosphoribosyl pyrophosphate synthetase 1 | H000502_01 | D00860 | 56 | PRPS1 | Histidine metabolism, Pentose phosphate pathway, Purine metabolism, gene_regulation, transcription | 0.3045664 | 0.909 |
| 296 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H008715_01 | Info | ATP-binding cassette, sub-family G (WHITE), member 1 | H008715_01 | X91249 | 10237 | ABCG1 | Nuclear Receptors in Lipid Metabolism and Toxicity | 0.4098523 | 1.096 |
| 297 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003763_01 | Info | Folate hydrolase (prostate-specific membrane antigen) 1 | H003763_01 | M99487 | 1915 | FOLH1 | 0.4171314 | 0.905 | |
| 298 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H013236_01 | Info | Monocyte to macrophage differentiation-associated | H013236_01 | X85750 | 79889 | MMD | 0.4241064 | 0.921 | |
| 299 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003935_01 | Info | KIAA0922 protein | H003935_01 | AB023139 | 37892 | KIAA0922 | 0.4306564 | 1.134 | |
| 300 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003371_01 | Info | Erythropoietin receptor | H003371_01 | NM_000121 | 89548 | EPOR | Perou’s – Intrinsic – Breast-Cancer-Genes, EPO Signaling Pathway, Erythropoietin mediated neuroprotection through NF-kB, immunology | 0.4485722 | 0.93 |
| 301 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H005832_01 | Info | Kynureninase (L-kynurenine hydrolase) | H005832_01 | U57721 | 169139 | KYNU | Tryptophan metabolism | 0.5223633 | 1.074 |
| 302 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H011966_01 | Info | Syntaxin binding protein 1 | H011966_01 | AF004563 | 239356 | STXBP1 | 0.5388587 | 1.065 | |
| 303 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H004814_01 | Info | N-myc downstream regulated | H004814_01 | D87953 | 75789 | NDRG1 | 0.5742952 | 1.047 | |
| 304 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003024_01 | Info | Cathepsin H | H003024_01 | X16832 | 288181 | CTSH | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.5964026 | 1.048 |
| 305 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H001606_01 | Info | Drebrin 1 | H001606_01 | AL110225 | 89434 | DBN1 | 0.6301138 | 1.048 | |
| 306 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H013890_01 | Info | Slit (Drosophila) homolog 2 | H013890_01 | AF055585 | 29802 | SLIT2 | 0.696259 | 0.965 | |
| 307 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H000900_01 | Info | Matrilin 2 | H000900_01 | AL137638 | 19368 | MATN2 | 0.7034604 | 0.949 | |
| 308 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003542_01 | Info | V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene | H003542_01 | M11730 | 323910 | ERBB2 | Perou’s – Intrinsic – Breast-Cancer-Genes, Role of ERBB2 in Signal Transduction and Oncology, Trefoil Factors Initiate Mucosal Healing, immunology, signal_transduction, tsonc | 0.7160857 | 1.031 |
| 309 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003155_01 | Info | CD24 antigen (small cell lung carcinoma cluster 4 antigen) | H003155_01 | L33930 | 286124 | CD24 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.7363586 | 0.966 |
| 310 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H003434_01 | Info | Dual specificity phosphatase 1 | H003434_01 | NM_004417 | 171695 | DUSP1 | CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway | 0.8183145 | 0.968 |
| 311 | FRASOR_ER_DOWN_h | Frasor_et_al_2004 | H001715_01 | Info | Dual specificity phosphatase 4 | H001715_01 | AL137704 | 2359 | DUSP4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, cell_cycle, cell_signaling | 0.9634643 | 1.004 |
| 312 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H000732_01 | Info | Insulin receptor substrate 1 | H000732_01 | S62539 | 96063 | IRS1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Insulin Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of eIF4e and p70 S6 Kinase, immunology | 0.0013348 | 0.643 |
| 313 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 314 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 315 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H001348_01 | Info | Phosphoinositide-3-kinase, catalytic, delta polypeptide | H001348_01 | U86453 | 162808 | PIK3CD | Inositol phosphate metabolism, Phosphatidylinositol signaling system | 0.0324563 | 1.426 |
| 316 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H016134_01 | Info | V-akt murine thymoma viral oncogene homolog 2 | H016134_01 | NM_001626 | 326445 | AKT2 | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.0530988 | 1.287 |
| 317 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 318 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H001349_01 | Info | Janus kinase 1 (a protein tyrosine kinase) | H001349_01 | M64174 | 50651 | JAK1 | EGF Signaling Pathway, IFN alpha signaling pathway, IFN gamma signaling pathway , IL 2 signaling pathway, IL 4 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, PDGF Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.2754104 | 1.129 |
| 319 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H003497_01 | Info | V-akt murine thymoma viral oncogene homolog 2 | H003497_01 | M77198 | 326445 | AKT2 | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.3314111 | 0.872 |
| 320 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H000650_01 | Info | Glycogen synthase kinase 3 beta | H000650_01 | L33801 | 78802 | GSK3B | ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system | 0.353328 | 1.118 |
| 321 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H002824_01 | Info | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | H002824_01 | U09607 | 99877 | JAK3 | IL 2 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, IL22 Soluble Receptor Signaling Pathway , IL-7 Signal Transduction, Stat3 Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.4735774 | 1.051 |
| 322 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H002236_01 | Info | Mitogen-activated protein kinase kinase kinase kinase 1 | H002236_01 | U66464 | 86575 | MAP4K1 | MAP Kinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system | 0.5747172 | 0.927 |
| 323 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 | 71816 | AKT1 | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 324 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES_h | Signalling Alliance | H001974_01 | Info | BCL2-antagonist of cell death | H001974_01 | U66879 | 76366 | BAD | AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development | 0.6985187 | 0.954 |
| 325 | mapkPathway_h | BioCarta | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 326 | mapkPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 327 | mapkPathway_h | BioCarta | H003232_01 | Info | Mitogen-activated protein kinase kinase kinase 14 | H003232_01 | Y10256 | 47007 | MAP3K14 | CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.005309 | 0.755 |
| 328 | mapkPathway_h | BioCarta | H002763_01 | Info | Mitogen-activated protein kinase kinase kinase 8 | H002763_01 | D14497 | 248 | MAP3K8 | MAP Kinase Signaling Pathway | 0.005954 | 1.333 |
| 329 | mapkPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 330 | mapkPathway_h | BioCarta | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 331 | mapkPathway_h | BioCarta | H002320_01 | Info | Ribosomal protein S6 kinase, 70kD, polypeptide 2 | H002320_01 | AB016869 | 103081 | RPS6KB2 | MAP Kinase Signaling Pathway | 0.0093261 | 0.755 |
| 332 | mapkPathway_h | BioCarta | H004176_01 | Info | Mitogen-activated protein kinase kinase kinase 11 | H004176_01 | L32976 | 89449 | MAP3K11 | MAP Kinase Signaling Pathway | 0.0101996 | 1.263 |
| 333 | mapkPathway_h | BioCarta | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 334 | mapkPathway_h | BioCarta | H003008_01 | Info | Mitogen-activated protein kinase kinase kinase 4 | H003008_01 | AF002715 | 32353 | MAP3K4 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.0127738 | 0.707 |
| 335 | mapkPathway_h | BioCarta | H002890_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 1 | H002890_01 | L07597 | 149957 | RPS6KA1 | Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system | 0.0138896 | 1.42 |
| 336 | mapkPathway_h | BioCarta | H003493_01 | Info | MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) | H003493_01 | X63380 | 78881 | MEF2B | 0.0145042 | 1.328 | |
| 337 | mapkPathway_h | BioCarta | H001992_01 | Info | Activating transcription factor 2 | H001992_01 | X15875 | 198166 | ATF2 | ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer | 0.0178377 | 0.749 |
| 338 | mapkPathway_h | BioCarta | H003305_01 | Info | Ribosomal protein S6 kinase, 70kD, polypeptide 1 | H003305_01 | M60724 | 86858 | RPS6KB1 | CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0214523 | 1.448 |
| 339 | mapkPathway_h | BioCarta | H000612_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 3 | H000612_01 | U08316 | 173965 | RPS6KA3 | MAP Kinase Signaling Pathway, Signaling Pathway from G-Protein Families, Phosphatidylinositol signaling system | 0.0473043 | 0.79 |
| 340 | mapkPathway_h | BioCarta | H003259_01 | Info | Sp1 transcription factor | H003259_01 | J03133 | 2021 | SP1 | Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation | 0.0557417 | 0.814 |
| 341 | mapkPathway_h | BioCarta | H011228_01 | Info | G protein-coupled receptor kinase 7 | H011228_01 | AL137615 | 261828 | GPRK7 | Perou’s – Intrinsic – Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.0572981 | 1.27 |
| 342 | mapkPathway_h | BioCarta | H000521_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 2 | H000521_01 | X85106 | 301664 | RPS6KA2 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0604408 | 1.207 |
| 343 | mapkPathway_h | BioCarta | H002588_01 | Info | Mitogen-activated protein kinase 7 | H002588_01 | U29725 | 3080 | MAPK7 | Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), MAP Kinase Signaling Pathway, Role of Erk5 in Neuronal Survival, Phosphatidylinositol signaling system | 0.0614441 | 0.811 |
| 344 | mapkPathway_h | BioCarta | H009683_01 | Info | Mitogen-activated protein kinase kinase kinase kinase 4 | H009683_01 | AB014587 | 3628 | MAP4K4 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.0707782 | 1.203 |
| 345 | mapkPathway_h | BioCarta | H003107_01 | Info | Mitogen-activated protein kinase 13 | H003107_01 | AF004709 | 178695 | MAPK13 | Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Stathmin and breast cancer resistance to antimicrotubule agents, Phosphatidylinositol signaling system | 0.0717244 | 1.171 |
| 346 | mapkPathway_h | BioCarta | H002049_01 | Info | Death-associated protein 6 | H002049_01 | AB015051 | 180224 | DAXX | FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of transcriptional activity by PML, Stress Induction of HSP Regulation, apoptosis | 0.0788021 | 1.159 |
| 347 | mapkPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 348 | mapkPathway_h | BioCarta | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 349 | mapkPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 350 | mapkPathway_h | BioCarta | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 | 79070 | MYC | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 351 | mapkPathway_h | BioCarta | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 352 | mapkPathway_h | BioCarta | H000029_01 | Info | Mitogen-activated protein kinase kinase kinase 3 | H000029_01 | U78876 | 29282 | MAP3K3 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.2027051 | 1.138 |
| 353 | mapkPathway_h | BioCarta | H002943_01 | Info | V-raf murine sarcoma viral oncogene homolog B1 | H002943_01 | M95712 | 622 | BRAF | MAP Kinase Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc | 0.2376595 | 0.895 |
| 354 | mapkPathway_h | BioCarta | H003309_01 | Info | Mitogen-activated protein kinase kinase 7 | H003309_01 | AF013589 | 110299 | MAP2K7 | Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway | 0.3044184 | 1.088 |
| 355 | mapkPathway_h | BioCarta | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 | 72241 | MAP2K2 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 356 | mapkPathway_h | BioCarta | H002660_01 | Info | TNFRSF1A-associated via death domain | H002660_01 | L41690 | 89862 | TRADD | Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , MAP Kinase Signaling Pathway, NF-kB Signaling Pathway, p38 MAPK Signaling Pathway , SODD/TNFR1 Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway | 0.3157474 | 1.092 |
| 357 | mapkPathway_h | BioCarta | H002559_01 | Info | Mitogen-activated protein kinase kinase kinase 12 | H002559_01 | U07358 | 211601 | MAP3K12 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.3172697 | 1.101 |
| 358 | mapkPathway_h | BioCarta | H000203_01 | Info | MAX protein | H000203_01 | X60287 | 42712 | MAX | MAP Kinase Signaling Pathway, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , gene_regulation, transcription, tsonc | 0.3220945 | 1.09 |
| 359 | mapkPathway_h | BioCarta | H002700_01 | Info | Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) | H002700_01 | L11695 | 220 | TGFBR1 | ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development | 0.3279632 | 0.903 |
| 360 | mapkPathway_h | BioCarta | H015286_01 | Info | Homo sapiens PAK2 mRNA, complete CDS | H015286_01 | AF092132 | 284275 | FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAP Kinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system | 0.4868167 | 1.068 | |
| 361 | mapkPathway_h | BioCarta | H001369_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 4 | H001369_01 | AJ010119 | 105584 | RPS6KA4 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.5303179 | 0.95 |
| 362 | mapkPathway_h | BioCarta | H002340_01 | Info | Mitogen-activated protein kinase kinase kinase 5 | H002340_01 | U67156 | 151988 | MAP3K5 | HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response | 0.5393151 | 1.07 |
| 363 | mapkPathway_h | BioCarta | H002236_01 | Info | Mitogen-activated protein kinase kinase kinase kinase 1 | H002236_01 | U66464 | 86575 | MAP4K1 | MAP Kinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system | 0.5747172 | 0.927 |
| 364 | mapkPathway_h | BioCarta | H010968_01 | Info | Mitogen-activated protein kinase kinase kinase 6 | H010968_01 | AF100318 | 194694 | MAP3K6 | MAP Kinase Signaling Pathway | 0.6538459 | 1.04 |
| 365 | mapkPathway_h | BioCarta | H001386_01 | Info | Mitogen-activated protein kinase kinase kinase 10 | H001386_01 | X90846 | 30223 | MAP3K10 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.7007387 | 0.968 |
| 366 | mapkPathway_h | BioCarta | H002757_01 | Info | Mitogen-activated protein kinase 6 | H002757_01 | X80692 | 271980 | MAPK6 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.7279385 | 1.033 |
| 367 | mapkPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 368 | mapkPathway_h | BioCarta | H002136_01 | Info | Mitogen-activating protein kinase kinase kinase kinase 2 | H002136_01 | U07349 | 82979 | MAP4K2 | MAP Kinase Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, TNF/Stress Related Signaling, Phosphatidylinositol signaling system | 0.8239916 | 1.021 |
| 369 | mapkPathway_h | BioCarta | H002447_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | H002447_01 | M69043 | 81328 | NFKBIA | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … | 0.8245205 | 0.975 |
| 370 | mapkPathway_h | BioCarta | H002580_01 | Info | Mitogen-activated protein kinase-activated protein kinase 3 | H002580_01 | U09578 | 227789 | MAPKAPK3 | MAP Kinase Signaling Pathway, Stress Induction of HSP Regulation, immunology | 0.8269383 | 0.981 |
| 371 | mapkPathway_h | BioCarta | H001376_01 | Info | Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) | H001376_01 | AL133012 | 306440 | Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction | 0.8639394 | 0.98 | |
| 372 | mapkPathway_h | BioCarta | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 373 | mapkPathway_h | BioCarta | H003860_01 | Info | Mitogen-activated protein kinase kinase kinase kinase 5 | H003860_01 | U77129 | 246970 | MAP4K5 | MAP Kinase Signaling Pathway, The 4-1BB-dependent immune response, Phosphatidylinositol signaling system | 0.8968151 | 1.015 |
| 374 | mapkPathway_h | BioCarta | H003773_01 | Info | Mitogen-activated protein kinase 4 | H003773_01 | X59727 | 269222 | MAPK4 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.91886 | 1.013 |
| 375 | mapkPathway_h | BioCarta | H003163_01 | Info | CAMP responsive element binding protein 1 | H003163_01 | M27691 | 79194 | CREB1 | Ca++/ Calmodulin-dependent Protein Kinase Activation, Calcium Signaling by HBx of Hepatitis B virus, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia-Inducible Factor in the Cardiovascular System, Inhibition of Huntington\’s disease neurodegeneration by histone deacetylase inhibitors, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Repression of Pain Sensation by the Transcriptional Regulator DREAM, Role of Erk5 in Neuronal Survival, Signaling Pathway from G-Protein Families, Transcription factor CREB and its extracellular signals, Transcription Regulation by Methyltransferase of CARM1, immunology | 0.9300928 | 1.009 |
| 376 | mapkPathway_h | BioCarta | H012856_01 | Info | MAP kinase-interacting serine/threonine kinase 1 | H012856_01 | AB000409 | 5591 | MKNK1 | Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system | 0.9455231 | 0.992 |
| 377 | mapkPathway_h | BioCarta | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 378 | mapkPathway_h | BioCarta | H014820_01 | Info | Mitogen-activated protein kinase 9 | H014820_01 | NM_002752 | 246857 | MAPK9 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.9883614 | 0.998 |
| 379 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001935_01 | Info | Glyceraldehyde-3-phosphate dehydrogenase | H001935_01 | U34995 | 169476 | GAPD | 0.0001082 | 1.485 | |
| 380 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H002486_01 | Info | Glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | H002486_01 | M90299 | 1270 | GCK | Aminosugars metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism, Streptomycin biosynthesis, immunology | 0.0014569 | 1.288 |
| 381 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H004823_01 | Info | Aldolase C, fructose-bisphosphate | H004823_01 | AF054987 | 155247 | ALDOC | Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway | 0.001576 | 0.707 |
| 382 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H003374_01 | Info | Aldolase A, fructose-bisphosphate | H003374_01 | M11560 | 273415 | ALDOA | Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology | 0.0300936 | 1.252 |
| 383 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001878_01 | Info | Enolase 1, (alpha) | H001878_01 | M14328 | 254105 | ENO1 | Glycolysis Pathway, Glycolysis / Gluconeogenesis, Phenylalanine, tyrosine and tryptophan biosynthesis | 0.0756084 | 1.187 |
| 384 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H007138_01 | Info | Phosphoglycerate kinase {alternatively spliced} [human, phosphoglycerate kinase deficient patient wi | H007138_01 | S81916 | 169313 | Glycolysis Pathway, Carbon fixation, Glycolysis / Gluconeogenesis, immunology | 0.0923463 | 1.164 | |
| 385 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001387_01 | Info | Phosphofructokinase, platelet | H001387_01 | D25328 | 99910 | PFKP | Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology | 0.101431 | 0.866 |
| 386 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001572_01 | Info | Aldehyde dehydrogenase 3 family, member B2 | H001572_01 | U37519 | 87539 | ALDH3B2 | Glycolysis / Gluconeogenesis, Histidine metabolism, Phenylalanine metabolism, Tyrosine metabolism | 0.1278934 | 0.831 |
| 387 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H005470_01 | Info | Homo sapiens mRNA; cDNA DKFZp762B245 (from clone DKFZp762B245); partial CDS | H005470_01 | AL162062 | 198182 | 0.1944956 | 1.125 | ||
| 388 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H002972_01 | Info | Lactate dehydrogenase A | H002972_01 | X02152 | 2795 | LDHA | Hypoxia-Inducible Factor in the Cardiovascular System, SARS Coronavirus Protease, Cysteine metabolism, Glycolysis / Gluconeogenesis, Propanoate metabolism, Pyruvate metabolism, immunology, misc | 0.2007271 | 0.841 |
| 389 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H003659_01 | Info | Aldehyde dehydrogenase 3 family, member A2 | H003659_01 | U46689 | 159608 | ALDH3A2 | Perou’s – Intrinsic – Breast-Cancer-Genes, Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation | 0.2326293 | 0.892 |
| 390 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001636_01 | Info | Phosphoglycerate mutase 1 (brain) | H001636_01 | J04173 | 181013 | PGAM1 | Glycolysis Pathway, Glycolysis / Gluconeogenesis, misc | 0.2631445 | 1.109 |
| 391 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001378_01 | Info | Phosphofructokinase, muscle | H001378_01 | U24183 | 75160 | PFKM | Phosphoinositides and their downstream targets., Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology | 0.2927445 | 0.908 |
| 392 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001136_01 | Info | Glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) | H001136_01 | U01120 | 242 | G6PC | Galactose metabolism, Glycolysis / Gluconeogenesis, Starch and sucrose metabolism | 0.3211576 | 0.901 |
| 393 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H003068_01 | Info | Pyruvate kinase, muscle | H003068_01 | M26252 | 198281 | PKM2 | Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism | 0.3246109 | 1.102 |
| 394 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H000053_01 | Info | BH3 interacting domain death agonist | H000053_01 | AF042083 | 172894 | BID | Apoptotic Signaling in Response to DNA Damage, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Role of Mitochondria in Apoptotic Signaling, immunology | 0.4598136 | 1.076 |
| 395 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H002609_01 | Info | Aldehyde dehydrogenase 3 family, member B1 | H002609_01 | U10868 | 83155 | ALDH3B1 | Glycolysis / Gluconeogenesis, Histidine metabolism, Phenylalanine metabolism, Tyrosine metabolism | 0.6584857 | 1.053 |
| 396 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001558_01 | Info | Lactate dehydrogenase C | H001558_01 | U13680 | 99881 | LDHC | 0.6951457 | 1.058 | |
| 397 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H003776_01 | Info | Aldehyde dehydrogenase 2 family (mitochondrial) | H003776_01 | X05409 | 195432 | ALDH2 | Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation, immunology, pharmacology | 0.7225282 | 0.971 |
| 398 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H005249_01 | Info | Homo sapiens 10q21 mRNA sequence | H005249_01 | AF198444 | 279024 | Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation | 0.761598 | 0.965 | |
| 399 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H006795_01 | Info | 2,3-bisphosphoglycerate mutase | H006795_01 | X04327 | 198365 | BPGM | Glycolysis / Gluconeogenesis | 0.8901914 | 1.013 |
| 400 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001385_01 | Info | Phosphofructokinase, liver | H001385_01 | X15573 | 155455 | PFKL | Glycolysis Pathway, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Pentose phosphate pathway, immunology | 0.9581627 | 1.005 |
| 401 | MAP00010_Glycolysis_Gluconeogenesis_h | GenMAPP | H001547_01 | Info | Aldehyde dehydrogenase 3 family, member A1 | H001547_01 | M74542 | 575 | ALDH3A1 | Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Bile acid biosynthesis, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Phenylalanine metabolism, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Tyrosine metabolism, Valine, leucine and isoleucine degradation | 0.999646 | 1 |
| 402 | pyk2Pathway_h | BioCarta | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 403 | pyk2Pathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 404 | pyk2Pathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 405 | pyk2Pathway_h | BioCarta | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 406 | pyk2Pathway_h | BioCarta | H002573_01 | Info | Protein tyrosine kinase 2 beta | H002573_01 | U43522 | 20313 | PTK2B | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction | 0.0091935 | 1.367 |
| 407 | pyk2Pathway_h | BioCarta | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 408 | pyk2Pathway_h | BioCarta | H003332_01 | Info | V-crk avian sarcoma virus CT10 oncogene homolog-like | H003332_01 | X59656 | 37078 | CRKL | IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc | 0.0164206 | 0.675 |
| 409 | pyk2Pathway_h | BioCarta | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 | 77202 | PRKCB1 | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 410 | pyk2Pathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 411 | pyk2Pathway_h | BioCarta | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 412 | pyk2Pathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 413 | pyk2Pathway_h | BioCarta | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 414 | pyk2Pathway_h | BioCarta | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 | 72241 | MAP2K2 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 415 | pyk2Pathway_h | BioCarta | H011336_01 | Info | Guanine nucleotide binding protein (G protein), q polypeptide | H011336_01 | U43083 | 296261 | GNAQ | Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology | 0.3713616 | 0.89 |
| 416 | pyk2Pathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 417 | pyk2Pathway_h | BioCarta | H002404_01 | Info | Synaptotagmin I | H002404_01 | M55047 | 154679 | SYT1 | 0.8170962 | 0.971 | |
| 418 | pyk2Pathway_h | BioCarta | H000579_01 | Info | Calmodulin 2 (phosphorylase kinase, delta) | H000579_01 | D45887 | 182278 | CALM2 | 0.9689776 | 1.004 | |
| 419 | mta3Pathway_h | BioCarta | H001935_01 | Info | Glyceraldehyde-3-phosphate dehydrogenase | H001935_01 | U34995 | 169476 | GAPD | 0.0001082 | 1.485 | |
| 420 | mta3Pathway_h | BioCarta | H002279_01 | Info | Metastasis associated 1 | H002279_01 | U35113 | 101448 | MTA1 | Downregulated of MTA-3 in ER-negative Breast Tumors | 0.0268932 | 0.814 |
| 421 | mta3Pathway_h | BioCarta | H003374_01 | Info | Aldolase A, fructose-bisphosphate | H003374_01 | M11560 | 273415 | ALDOA | Downregulated of MTA-3 in ER-negative Breast Tumors, Carbon fixation, Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Inositol metabolism, Pentose phosphate pathway, immunology | 0.0300936 | 1.252 |
| 422 | mta3Pathway_h | BioCarta | H015409_01 | Info | Hypothetical protein FLJ13940 | H015409_01 | NM_025019 | 287610 | FLJ13940 | 0.0928487 | 1.183 | |
| 423 | mta3Pathway_h | BioCarta | H003339_01 | Info | Heat shock 27kD protein 2 | H003339_01 | D89617 | 78846 | HSPB2 | 0.4094065 | 0.924 | |
| 424 | gata3Pathway_h | BioCarta | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 425 | gata3Pathway_h | BioCarta | H002406_01 | Info | Jun B proto-oncogene | H002406_01 | X51345 | 198951 | JUNB | GATA3 participate in activating the Th2 cytokine genes expression, tsonc | 0.0021761 | 1.408 |
| 426 | gata3Pathway_h | BioCarta | H003415_01 | Info | Protein kinase, cAMP-dependent, catalytic, beta | H003415_01 | M34181 | 87773 | PRKACB | Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0048904 | 0.647 |
| 427 | gata3Pathway_h | BioCarta | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 428 | gata3Pathway_h | BioCarta | H006601_01 | Info | V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog | H006601_01 | AF055376 | 30250 | MAF | GATA3 participate in activating the Th2 cytokine genes expression, tsonc | 0.079493 | 0.812 |
| 429 | gata3Pathway_h | BioCarta | H001698_01 | Info | Protein kinase, cAMP-dependent, regulatory, type II, alpha | H001698_01 | X14968 | 289075 | PRKAR2A | AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation | 0.2569617 | 1.125 |
| 430 | gata3Pathway_h | BioCarta | H000645_01 | Info | Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | H000645_01 | M33336 | 183037 | PRKAR1A | Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction | 0.4305614 | 0.935 |
| 431 | gata3Pathway_h | BioCarta | H002045_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | H002045_01 | U80917 | 96149 | NFATC1 | BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology | 0.623508 | 1.051 |
| 432 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H000403_01 | Info | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | H000403_01 | M33195 | 743 | FCER1G | Fc Epsilon Receptor I Signaling in Mast Cells | 0.0002683 | 2.278 |
| 433 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 434 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 435 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002878_01 | Info | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog | H002878_01 | M16038 | 80887 | LYN | BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc | 0.0068841 | 1.545 |
| 436 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 437 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 | 77202 | PRKCB1 | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 438 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 439 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 440 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H003870_01 | Info | Bruton agammaglobulinemia tyrosine kinase | H003870_01 | NM_000061 | 159494 | BTK | BCR Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., cell_cycle, cell_signaling, immunology, signal_transduction | 0.251649 | 1.148 |
| 441 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H003309_01 | Info | Mitogen-activated protein kinase kinase 7 | H003309_01 | AF013589 | 110299 | MAP2K7 | Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway | 0.3044184 | 1.088 |
| 442 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H001979_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | H001979_01 | M29551 | 151531 | PPP3CB | cell_cycle, cell_signaling | 0.3386238 | 0.898 |
| 443 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H015286_01 | Info | Homo sapiens PAK2 mRNA, complete CDS | H015286_01 | AF092132 | 284275 | FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, MAP Kinase Signaling Pathway, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system | 0.4868167 | 1.068 | |
| 444 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H003578_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | H003578_01 | S46622 | 75206 | PPP3CC | 0.5197011 | 0.934 | |
| 445 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002045_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | H002045_01 | U80917 | 96149 | NFATC1 | BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology | 0.623508 | 1.051 |
| 446 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H000983_01 | Info | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | H000983_01 | X06948 | 897 | FCER1A | Fc Epsilon Receptor I Signaling in Mast Cells, immunology | 0.6468177 | 0.954 |
| 447 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002470_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | H002470_01 | L41067 | 172674 | NFATC3 | immunology | 0.7190859 | 0.97 |
| 448 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 449 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H002404_01 | Info | Synaptotagmin I | H002404_01 | M55047 | 154679 | SYT1 | 0.8170962 | 0.971 | |
| 450 | fcer1Pathway_h | In mast cells, Fc epsilon receptor 1 activates BTK, PKC, and the MAP kinase pathway to promote degranulation and arachidonic acid release. | H000579_01 | Info | Calmodulin 2 (phosphorylase kinase, delta) | H000579_01 | D45887 | 182278 | CALM2 | 0.9689776 | 1.004 | |
| 451 | metPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 452 | metPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 453 | metPathway_h | BioCarta | H002573_01 | Info | Protein tyrosine kinase 2 beta | H002573_01 | U43522 | 20313 | PTK2B | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction | 0.0091935 | 1.367 |
| 454 | metPathway_h | BioCarta | H003332_01 | Info | V-crk avian sarcoma virus CT10 oncogene homolog-like | H003332_01 | X59656 | 37078 | CRKL | IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc | 0.0164206 | 0.675 |
| 455 | metPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 456 | metPathway_h | BioCarta | H001600_01 | Info | RAS p21 protein activator (GTPase activating protein) 1 | H001600_01 | M23379 | 758 | RASA1 | EGF Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, IGF-1 Signaling Pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Regulation of Splicing through Sam68, Signaling of Hepatocyte Growth Factor Receptor, Sprouty regulation of tyrosine kinase signals, T Cell Receptor Signaling Pathway, TPO Signaling Pathway, cell_signaling, signal_transduction | 0.1015906 | 0.844 |
| 457 | metPathway_h | BioCarta | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 458 | metPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 459 | metPathway_h | BioCarta | H002112_01 | Info | PTK2 protein tyrosine kinase 2 | H002112_01 | L13616 | 740 | PTK2 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction | 0.2346929 | 0.896 |
| 460 | metPathway_h | BioCarta | H002632_01 | Info | GRB2-associated binding protein 1 | H002632_01 | U43885 | 239706 | GAB1 | Signaling of Hepatocyte Growth Factor Receptor | 0.3021702 | 1.095 |
| 461 | metPathway_h | BioCarta | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 | 72241 | MAP2K2 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 462 | metPathway_h | BioCarta | H000015_01 | Info | Dedicator of cyto-kinesis 1 | H000015_01 | D50857 | 82295 | DOCK1 | Signaling of Hepatocyte Growth Factor Receptor, immunology | 0.334442 | 0.886 |
| 463 | metPathway_h | BioCarta | H003533_01 | Info | Paxillin | H003533_01 | U14588 | 102497 | PXN | Agrin in Postsynaptic Differentiation, Apoptotic Signaling in Response to DNA Damage, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Signaling of Hepatocyte Growth Factor Receptor, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, immunology | 0.4629128 | 1.067 |
| 464 | metPathway_h | BioCarta | H002236_01 | Info | Mitogen-activated protein kinase kinase kinase kinase 1 | H002236_01 | U66464 | 86575 | MAP4K1 | MAP Kinase Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor, Phosphatidylinositol signaling system | 0.5747172 | 0.927 |
| 465 | metPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 466 | metPathway_h | BioCarta | H003724_01 | Info | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | H003724_01 | NM_002211 | 202661 | ITGB1 | Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis | 0.9378203 | 0.993 |
| 467 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002800_01 | Info | Connective tissue growth factor | H002800_01 | X78947 | 75511 | CTGF | immunology, misc | 0.0004011 | 0.555 |
| 468 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002931_01 | Info | Selectin L (lymphocyte adhesion molecule 1) | H002931_01 | M25280 | 82848 | SELL | Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, cell_signaling, immunology, metastasis | 0.0013165 | 2.024 |
| 469 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 470 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000459_01 | Info | Serine protease inhibitor, Kunitz type, 2 | H000459_01 | AF027205 | 31439 | SPINT2 | 0.009031 | 0.736 | |
| 471 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002944_01 | Info | Interleukin 8 | H002944_01 | M17017 | 624 | IL8 | Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology | 0.0100881 | 0.681 |
| 472 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003332_01 | Info | V-crk avian sarcoma virus CT10 oncogene homolog-like | H003332_01 | X59656 | 37078 | CRKL | IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, Signaling of Hepatocyte Growth Factor Receptor, tsonc | 0.0164206 | 0.675 |
| 473 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000633_01 | Info | Coronin, actin-binding protein, 1A | H000633_01 | D44497 | 109606 | CORO1A | 0.0167926 | 1.342 | |
| 474 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002936_01 | Info | Macrophage stimulating 1 receptor (c-met-related tyrosine kinase) | H002936_01 | X70040 | 2942 | MST1R | Msp/Ron Receptor Signaling Pathway, cell_cycle, cell_signaling, immunology, signal_transduction | 0.0189711 | 0.747 |
| 475 | cell_motility_h | Any process involved in the controlled movement of a cell. | H004577_01 | Info | Vasodilator-stimulated phosphoprotein | H004577_01 | Z46389 | 93183 | VASP | cell_signaling, immunology, signal_transduction | 0.0236006 | 1.288 |
| 476 | cell_motility_h | Any process involved in the controlled movement of a cell. | H004361_01 | Info | Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial CDS | H004361_01 | AF065241 | 306243 | Chaperones modulate interferon Signaling Pathway, immunology | 0.028408 | 1.271 | |
| 477 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002347_01 | Info | Leukotriene b4 receptor (chemokine receptor-like 1) | H002347_01 | D89078 | 28408 | LTB4R | immunology | 0.0284508 | 1.35 |
| 478 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002869_01 | Info | Platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD) | H002869_01 | NM_000430 | 77318 | PAFAH1B1 | Glycerophospholipid metabolism, immunology | 0.0323993 | 0.822 |
| 479 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003130_01 | Info | Interleukin 8 receptor, beta | H003130_01 | L19593 | 846 | IL8RB | immunology | 0.0345675 | 1.307 |
| 480 | cell_motility_h | Any process involved in the controlled movement of a cell. | H001342_01 | Info | Lymphocyte-specific protein 1 | H001342_01 | M33552 | 56729 | LSP1 | immunology | 0.0390011 | 1.407 |
| 481 | cell_motility_h | Any process involved in the controlled movement of a cell. | H015282_01 | Info | Dynein, axonemal, heavy polypeptide 9 | H015282_01 | AJ404468 | 284259 | DNAH9 | 0.0393936 | 1.221 | |
| 482 | cell_motility_h | Any process involved in the controlled movement of a cell. | H005850_01 | Info | Dynein, axonemal, heavy polypeptide 17-like | H005850_01 | AB002355 | 169148 | DNAH17L | 0.0500062 | 1.217 | |
| 483 | cell_motility_h | Any process involved in the controlled movement of a cell. | H012622_01 | Info | Actin related protein 2/3 complex, subunit 1A (41 kD) | H012622_01 | AF006084 | 11538 | ARPC1B | 0.0686508 | 1.204 | |
| 484 | cell_motility_h | Any process involved in the controlled movement of a cell. | H001765_01 | Info | Myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) | H001765_01 | D10522 | 75607 | MACS | Effects of calcineurin in Keratinocyte Differentiation | 0.1075359 | 1.166 |
| 485 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002937_01 | Info | Fibronectin 1 | H002937_01 | X02761 | 287820 | FN1 | angiogenesis, cell_signaling, immunology, metastasis | 0.128354 | 1.194 |
| 486 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 487 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000967_01 | Info | Thrombospondin 4 | H000967_01 | Z19585 | 75774 | THBS4 | angiogenesis | 0.1424962 | 0.85 |
| 488 | cell_motility_h | Any process involved in the controlled movement of a cell. | H015328_01 | Info | Junctional adhesion molecule | H015328_01 | AF172398 | 286218 | JAM | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.1497802 | 1.165 |
| 489 | cell_motility_h | Any process involved in the controlled movement of a cell. | H011553_01 | Info | Katanin p80 (WD40-containing) subunit B 1 | H011553_01 | AF052432 | 275675 | KATNB1 | 0.1512807 | 0.867 | |
| 490 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003564_01 | Info | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | H003564_01 | AB002329 | 212414 | SEMA3E | 0.1517956 | 0.885 | |
| 491 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002110_01 | Info | Coagulation factor II (thrombin) receptor | H002110_01 | NM_001992 | 128087 | F2R | Perou’s – Intrinsic – Breast-Cancer-Genes, Acute Myocardial Infarction, Extrinsic Prothrombin Activation Pathway, Fibrinolysis Pathway, Intrinsic Prothrombin Activation Pathway, immunology | 0.1560498 | 0.883 |
| 492 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 493 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002477_01 | Info | Neogenin (chicken) homolog 1 | H002477_01 | U61262 | 90408 | NEO1 | angiogenesis, metastasis | 0.2084414 | 1.135 |
| 494 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002750_01 | Info | Neuropeptide Y | H002750_01 | K01911 | 1832 | NPY | 0.2221305 | 1.126 | |
| 495 | cell_motility_h | Any process involved in the controlled movement of a cell. | H010731_01 | Info | Partner of RAC1 (arfaptin 2) | H010731_01 | U52522 | 75139 | POR1 | Rac 1 cell motility signaling pathway | 0.259825 | 0.88 |
| 496 | cell_motility_h | Any process involved in the controlled movement of a cell. | H007632_01 | Info | Type I transmembrane protein Fn14 | H007632_01 | AB035480 | 10086 | FN14 | 0.2727261 | 0.885 | |
| 497 | cell_motility_h | Any process involved in the controlled movement of a cell. | H005765_01 | Info | A kinase (PRKA) anchor protein 3 | H005765_01 | NM_006422 | 98397 | AKAP3 | 0.2830261 | 1.114 | |
| 498 | cell_motility_h | Any process involved in the controlled movement of a cell. | H005714_01 | Info | A kinase (PRKA) anchor protein 4 | H005714_01 | AF072756 | 97633 | AKAP4 | 0.284392 | 1.108 | |
| 499 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000220_01 | Info | Guanine nucleotide binding protein (G protein), alpha 13 | H000220_01 | L22075 | 1666 | GNA13 | PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Thrombin signaling and protease-activated receptors | 0.2922764 | 1.182 |
| 500 | cell_motility_h | Any process involved in the controlled movement of a cell. | H013061_01 | Info | Cerebral cell adhesion molecule | H013061_01 | NM_016174 | 23954 | LOC51148 | 0.3332267 | 0.884 | |
| 501 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002922_01 | Info | Annexin A1 | H002922_01 | X05908 | 78225 | ANXA1 | Corticosteroids and cardioprotection | 0.348625 | 1.12 |
| 502 | cell_motility_h | Any process involved in the controlled movement of a cell. | H013901_01 | Info | Protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs | H013901_01 | AB032968 | 20447 | PAK4 | Phosphatidylinositol signaling system | 0.3636917 | 0.913 |
| 503 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000723_01 | Info | Angio-associated, migratory cell protein | H000723_01 | M95627 | 83347 | AAMP | 0.3859087 | 0.934 | |
| 504 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002976_01 | Info | G protein-coupled receptor 9 | H002976_01 | X95876 | 198252 | GPR9 | IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization | 0.4390046 | 0.918 |
| 505 | cell_motility_h | Any process involved in the controlled movement of a cell. | H013376_01 | Info | Capping protein (actin filament) muscle Z-line, alpha 2 | H013376_01 | U03851 | 75546 | CAPZA2 | 0.4421974 | 1.117 | |
| 506 | cell_motility_h | Any process involved in the controlled movement of a cell. | H011225_01 | Info | Serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2 | H011225_01 | AB006423 | 158308 | SERPINI2 | 0.4705964 | 0.919 | |
| 507 | cell_motility_h | Any process involved in the controlled movement of a cell. | H004767_01 | Info | Tetraspan 3 | H004767_01 | AK001326 | 100090 | TSPAN-3 | 0.4723725 | 1.074 | |
| 508 | cell_motility_h | Any process involved in the controlled movement of a cell. | H015920_01 | Info | Homo sapiens thioredoxin delta 3 (TXN delta 3) mRNA, partial CDS | H015920_01 | AF065241 | 306243 | Chaperones modulate interferon Signaling Pathway, immunology | 0.5292008 | 1.077 | |
| 509 | cell_motility_h | Any process involved in the controlled movement of a cell. | H010773_01 | Info | Actin related protein 2/3 complex, subunit 4 (20 kD) | H010773_01 | AF006087 | 323342 | ARPC4 | 0.5595709 | 0.946 | |
| 510 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000791_01 | Info | Platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD) | H000791_01 | D63390 | 93354 | PAFAH1B2 | immunology | 0.5668546 | 0.933 |
| 511 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003496_01 | Info | Small inducible cytokine subfamily B (Cys-X-Cys), member 10 | H003496_01 | X02530 | 2248 | SCYB10 | 0.572348 | 1.053 | |
| 512 | cell_motility_h | Any process involved in the controlled movement of a cell. | H007284_01 | Info | Chondroitin sulfate proteoglycan 4 (melanoma-associated) | H007284_01 | X96753 | 9004 | CSPG4 | 0.6004302 | 0.95 | |
| 513 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003538_01 | Info | Actin, beta | H003538_01 | NM_001101 | 288061 | ACTB | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes | 0.6253266 | 0.956 |
| 514 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003708_01 | Info | Thioredoxin | H003708_01 | X77584 | 76136 | TXN | Chaperones modulate interferon Signaling Pathway, immunology | 0.6582476 | 1.041 |
| 515 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 516 | cell_motility_h | Any process involved in the controlled movement of a cell. | H006937_01 | Info | Hypothetical protein FLJ10211 | H006937_01 | AK001073 | 274206 | FLJ10211 | 0.8108637 | 0.973 | |
| 517 | cell_motility_h | Any process involved in the controlled movement of a cell. | H006776_01 | Info | Tetraspan 1 | H006776_01 | AF065388 | 38972 | TSPAN-1 | 0.819954 | 1.022 | |
| 518 | cell_motility_h | Any process involved in the controlled movement of a cell. | H013182_01 | Info | ARP2 (actin-related protein 2, yeast) homolog | H013182_01 | AF006082 | 42915 | ACTR2 | 0.840062 | 0.978 | |
| 519 | cell_motility_h | Any process involved in the controlled movement of a cell. | H007017_01 | Info | Extracellular link domain-containing 1 | H007017_01 | NM_006691 | 17917 | XLKD1 | 0.841013 | 0.971 | |
| 520 | cell_motility_h | Any process involved in the controlled movement of a cell. | H011434_01 | Info | ARP3 (actin-related protein 3, yeast) homolog | H011434_01 | NM_005721 | 5321 | ACTR3 | 0.8741333 | 1.017 | |
| 521 | cell_motility_h | Any process involved in the controlled movement of a cell. | H003854_01 | Info | Burkitt lymphoma receptor 1, GTP-binding protein | H003854_01 | X68149 | 113916 | BLR1 | 0.882872 | 0.982 | |
| 522 | cell_motility_h | Any process involved in the controlled movement of a cell. | H002891_01 | Info | Small inducible cytokine A4 (homologous to mouse Mip-1b) | H002891_01 | J04130 | 75703 | SCYA4 | Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization | 0.8975649 | 1.014 |
| 523 | cell_motility_h | Any process involved in the controlled movement of a cell. | H000822_01 | Info | Filamin A, alpha (actin-binding protein-280) | H000822_01 | X53416 | 195464 | FLNA | cell_signaling, metastasis | 0.9573941 | 1.004 |
| 524 | cell_motility_h | Any process involved in the controlled movement of a cell. | H009065_01 | Info | Muskelin 1, intracellular mediator containing kelch motifs | H009065_01 | NM_013255 | 288791 | MKLN1 | 0.9931275 | 1.001 | |
| 525 | ca_nf_at_signaling_h | GEArray | H001935_01 | Info | Glyceraldehyde-3-phosphate dehydrogenase | H001935_01 | U34995 | 169476 | GAPD | 0.0001082 | 1.485 | |
| 526 | ca_nf_at_signaling_h | GEArray | H001032_01 | Info | Cytotoxic T-lymphocyte-associated protein 4 | H001032_01 | L15006 | 247824 | CTLA4 | The Co-Stimulatory Signal During T-cell Activation, immunology | 0.0001134 | 0.56 |
| 527 | ca_nf_at_signaling_h | GEArray | H003672_01 | Info | FOS-like antigen-1 | H003672_01 | X16707 | 283565 | FOSL1 | Bone Remodelling, tsonc | 0.0019097 | 0.779 |
| 528 | ca_nf_at_signaling_h | GEArray | H002406_01 | Info | Jun B proto-oncogene | H002406_01 | X51345 | 198951 | JUNB | GATA3 participate in activating the Th2 cytokine genes expression, tsonc | 0.0021761 | 1.408 |
| 529 | ca_nf_at_signaling_h | GEArray | H000570_01 | Info | CREB binding protein (Rubinstein-Taybi syndrome) | H000570_01 | U47741 | 23598 | CREBBP | gene_regulation, transcription | 0.0048718 | 1.469 |
| 530 | ca_nf_at_signaling_h | GEArray | H008667_01 | Info | Calcineurin binding protein 1 | H008667_01 | NM_012295 | 7840 | KIAA0330 | Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Role of MEF2D in T-cell Apoptosis | 0.0071054 | 1.322 |
| 531 | ca_nf_at_signaling_h | GEArray | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 532 | ca_nf_at_signaling_h | GEArray | H002944_01 | Info | Interleukin 8 | H002944_01 | M17017 | 624 | IL8 | Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology | 0.0100881 | 0.681 |
| 533 | ca_nf_at_signaling_h | GEArray | H002831_01 | Info | Fc fragment of IgG, low affinity IIIb, receptor for (CD16) | H002831_01 | J04162 | 176663 | FCGR3B | immunology | 0.0108963 | 1.803 |
| 534 | ca_nf_at_signaling_h | GEArray | H003493_01 | Info | MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) | H003493_01 | X63380 | 78881 | MEF2B | 0.0145042 | 1.328 | |
| 535 | ca_nf_at_signaling_h | GEArray | H015723_01 | Info | Fc fragment of IgG, low affinity IIIa, receptor for (CD16) | H015723_01 | NM_000569 | 300983 | FCGR3A | immunology | 0.0160639 | 1.577 |
| 536 | ca_nf_at_signaling_h | GEArray | H002997_01 | Info | Vascular endothelial growth factor | H002997_01 | AF022375 | 73793 | VEGF | Actions of Nitric Oxide in the Heart, Hypoxia-Inducible Factor in the Cardiovascular System, VEGF, Hypoxia, and Angiogenesis, angiogenesis, misc | 0.0306231 | 0.782 |
| 537 | ca_nf_at_signaling_h | GEArray | H000343_01 | Info | Early growth response 3 | H000343_01 | X63741 | 74088 | EGR3 | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, cell_signaling | 0.0317099 | 0.777 |
| 538 | ca_nf_at_signaling_h | GEArray | H002149_01 | Info | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | H002149_01 | U03106 | 179665 | CDKN1A | ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc | 0.0349766 | 1.236 |
| 539 | ca_nf_at_signaling_h | GEArray | H001320_01 | Info | GATA-binding protein 4 | H001320_01 | L34357 | 243987 | GATA4 | ALK in cardiac myocytes, Hop Pathway in Cardiac Development, NFAT and Hypertrophy of the heart (Transcription in the broken heart), gene_regulation, misc, transcription | 0.0421967 | 0.782 |
| 540 | ca_nf_at_signaling_h | GEArray | H003259_01 | Info | Sp1 transcription factor | H003259_01 | J03133 | 2021 | SP1 | Agrin in Postsynaptic Differentiation, Effects of calcineurin in Keratinocyte Differentiation, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation | 0.0557417 | 0.814 |
| 541 | ca_nf_at_signaling_h | GEArray | H002545_01 | Info | CD69 antigen (p60, early T-cell activation antigen) | H002545_01 | Z22576 | 82401 | CD69 | cell_cycle, cell_signaling, immunology | 0.0914627 | 1.212 |
| 542 | ca_nf_at_signaling_h | GEArray | H002710_01 | Info | Interleukin 10 | H002710_01 | M57627 | 193717 | IL10 | Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, IL-10 Anti-inflammatory Signaling Pathway, immunology | 0.0986725 | 0.876 |
| 543 | ca_nf_at_signaling_h | GEArray | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 544 | ca_nf_at_signaling_h | GEArray | H000398_01 | Info | Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 | H000398_01 | U49070 | 161362 | PIN1 | How Progesterone Initiates the Oocyte Maturation | 0.1163659 | 1.163 |
| 545 | ca_nf_at_signaling_h | GEArray | H001128_01 | Info | Fc fragment of IgG, low affinity IIIb, receptor for (CD16) | H001128_01 | X16863 | 176663 | FCGR3B | immunology | 0.1164721 | 1.303 |
| 546 | ca_nf_at_signaling_h | GEArray | H010696_01 | Info | NCK adaptor protein 2 | H010696_01 | AF047487 | 101695 | NCK2 | 0.1245534 | 1.19 | |
| 547 | ca_nf_at_signaling_h | GEArray | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 548 | ca_nf_at_signaling_h | GEArray | H014546_01 | Info | Peptidylprolyl isomerase A (cyclophilin A) | H014546_01 | NM_021130 | 182937 | PPIA | IL-2 Receptor Beta Chain in T cell Activation | 0.129858 | 1.176 |
| 549 | ca_nf_at_signaling_h | GEArray | H012917_01 | Info | Homo sapiens clone 25048 mRNA sequence | H012917_01 | AF131776 | 321572 | 0.1524925 | 0.87 | ||
| 550 | ca_nf_at_signaling_h | GEArray | H003550_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | H003550_01 | S76638 | 73090 | NFKB2 | gene_regulation, immunology, transcription, tsonc | 0.1593331 | 1.165 |
| 551 | ca_nf_at_signaling_h | GEArray | H000372_01 | Info | Early growth response 2 (Krox-20 (Drosophila) homolog) | H000372_01 | NM_000399 | 1395 | EGR2 | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, immunology | 0.1772326 | 0.796 |
| 552 | ca_nf_at_signaling_h | GEArray | H003309_01 | Info | Mitogen-activated protein kinase kinase 7 | H003309_01 | AF013589 | 110299 | MAP2K7 | Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Keratinocyte Differentiation, MAP Kinase Signaling Pathway | 0.3044184 | 1.088 |
| 553 | ca_nf_at_signaling_h | GEArray | H001979_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | H001979_01 | M29551 | 151531 | PPP3CB | cell_cycle, cell_signaling | 0.3386238 | 0.898 |
| 554 | ca_nf_at_signaling_h | GEArray | H000650_01 | Info | Glycogen synthase kinase 3 beta | H000650_01 | L33801 | 78802 | GSK3B | ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system | 0.353328 | 1.118 |
| 555 | ca_nf_at_signaling_h | GEArray | H001957_01 | Info | Interleukin 1, beta | H001957_01 | M15330 | 126256 | IL1B | IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology | 0.4390274 | 1.089 |
| 556 | ca_nf_at_signaling_h | GEArray | H003578_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | H003578_01 | S46622 | 75206 | PPP3CC | 0.5197011 | 0.934 | |
| 557 | ca_nf_at_signaling_h | GEArray | H002104_01 | Info | Nucleoporin 214kD (CAIN) | H002104_01 | D14689 | 170285 | NUP214 | 0.5384146 | 1.074 | |
| 558 | ca_nf_at_signaling_h | GEArray | H001952_01 | Info | Ribosomal protein L13a | H001952_01 | X56932 | 119122 | RPL13A | 0.565051 | 1.059 | |
| 559 | ca_nf_at_signaling_h | GEArray | H003650_01 | Info | Interleukin 2 receptor, alpha | H003650_01 | X01057 | 1724 | IL2RA | IL 2 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Role of Tob in T-cell activation, Th1/Th2 Differentiation, immunology | 0.5932248 | 1.054 |
| 560 | ca_nf_at_signaling_h | GEArray | H007966_01 | Info | FK506-binding protein 1B (12.6 kD) | H007966_01 | D38037 | 77643 | FKBP1B | 0.6042574 | 0.956 | |
| 561 | ca_nf_at_signaling_h | GEArray | H012106_01 | Info | Src-like-adapter | H012106_01 | D89077 | 75367 | SLA | 0.6044071 | 0.939 | |
| 562 | ca_nf_at_signaling_h | GEArray | H002812_01 | Info | Protein tyrosine phosphatase, receptor type, C | H002812_01 | Y00062 | 170121 | PTPRC | Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, B Lymphocyte Cell Surface Molecules, Lck and Fyn tyrosine kinases in initiation of TCR Activation, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_cycle, cell_signaling, immunology | 0.6066202 | 1.093 |
| 563 | ca_nf_at_signaling_h | GEArray | H006762_01 | Info | Alu-binding protein with zinc finger domain | H006762_01 | U82613 | 289104 | ABP/ZF | 0.6091962 | 0.938 | |
| 564 | ca_nf_at_signaling_h | GEArray | H002045_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | H002045_01 | U80917 | 96149 | NFATC1 | BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology | 0.623508 | 1.051 |
| 565 | ca_nf_at_signaling_h | GEArray | H003538_01 | Info | Actin, beta | H003538_01 | NM_001101 | 288061 | ACTB | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes | 0.6253266 | 0.956 |
| 566 | ca_nf_at_signaling_h | GEArray | H000983_01 | Info | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | H000983_01 | X06948 | 897 | FCER1A | Fc Epsilon Receptor I Signaling in Mast Cells, immunology | 0.6468177 | 0.954 |
| 567 | ca_nf_at_signaling_h | GEArray | H002570_01 | Info | Interleukin 2 | H002570_01 | S82692 | 89679 | IL2 | Antigen Dependent B Cell Activation, Cytokine Network, Cytokines and Inflammatory Response, IL 18 Signaling Pathway, IL 2 signaling pathway, OX40 Signaling Pathway, Regulation of hematopoiesis by cytokines, Role of Tob in T-cell activation, Selective expression of chemokine receptors during T-cell polarization, Th1/Th2 Differentiation, The 4-1BB-dependent immune response, The Co-Stimulatory Signal During T-cell Activation, immunology | 0.6483346 | 1.043 |
| 568 | ca_nf_at_signaling_h | GEArray | H003110_01 | Info | Interleukin 6 (interferon, beta 2) | H003110_01 | X04430 | 93913 | IL6 | Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology | 0.680804 | 1.036 |
| 569 | ca_nf_at_signaling_h | GEArray | H001974_01 | Info | BCL2-antagonist of cell death | H001974_01 | U66879 | 76366 | BAD | AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phosphoinositides and their downstream targets., Ras Signaling Pathway, Regulation of BAD phosphorylation, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Trefoil Factors Initiate Mucosal Healing, apoptosis, development | 0.6985187 | 0.954 |
| 570 | ca_nf_at_signaling_h | GEArray | H003153_01 | Info | Interleukin 3 (colony-stimulating factor, multiple) | H003153_01 | M20137 | 694 | IL3 | Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 3 signaling pathway, Regulation of BAD phosphorylation, Regulation of hematopoiesis by cytokines, The Role of Eosinophils in the Chemokine Network of Allergy, immunology | 0.7001094 | 1.037 |
| 571 | ca_nf_at_signaling_h | GEArray | H002470_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | H002470_01 | L41067 | 172674 | NFATC3 | immunology | 0.7190859 | 0.97 |
| 572 | ca_nf_at_signaling_h | GEArray | H003043_01 | Info | Tumor necrosis factor (ligand) superfamily, member 5 (hyper-IgM syndrome) | H003043_01 | X68550 | 652 | TNFSF5 | angiogenesis, cell_cycle, cell_signaling, immunology, metastasis | 0.7231202 | 1.028 |
| 573 | ca_nf_at_signaling_h | GEArray | H001267_01 | Info | CD3Z antigen, zeta polypeptide (TiT3 complex) | H001267_01 | NM_000734 | 97087 | CD3Z | immunology | 0.8300402 | 1.024 |
| 574 | ca_nf_at_signaling_h | GEArray | H011554_01 | Info | Vav 3 oncogene | H011554_01 | NM_006113 | 267659 | VAV3 | 0.8411784 | 1.028 | |
| 575 | ca_nf_at_signaling_h | GEArray | H012662_01 | Info | Homo sapiens cDNA FLJ10205 fis, clone HEMBA1004954 | H012662_01 | AK001067 | 6226 | 0.8484663 | 1.017 | ||
| 576 | ca_nf_at_signaling_h | GEArray | H011889_01 | Info | Glucocorticoid receptor DNA binding factor 1 | H011889_01 | M73077 | 102548 | GRLF1 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.876973 | 0.984 |
| 577 | ca_nf_at_signaling_h | GEArray | H012455_01 | Info | KIAA1291 protein | H012455_01 | AB033117 | 9805 | KIAA1291 | 0.9257104 | 1.011 | |
| 578 | ca_nf_at_signaling_h | GEArray | H003151_01 | Info | E1A binding protein p300 | H003151_01 | U01877 | 25272 | EP300 | Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription | 0.9607239 | 1.004 |
| 579 | ca_nf_at_signaling_h | GEArray | H000579_01 | Info | Calmodulin 2 (phosphorylase kinase, delta) | H000579_01 | D45887 | 182278 | CALM2 | 0.9689776 | 1.004 | |
| 580 | ca_nf_at_signaling_h | GEArray | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 581 | ca_nf_at_signaling_h | GEArray | H000247_01 | Info | Sp3 transcription factor | H000247_01 | X68560 | 44450 | SP3 | Effects of calcineurin in Keratinocyte Differentiation, Overview of telomerase protein component gene hTert Transcriptional Regulation , Overview of telomerase RNA component gene hTerc Transcriptional Regulation | 0.985621 | 0.998 |
| 582 | ca_nf_at_signaling_h | GEArray | H014820_01 | Info | Mitogen-activated protein kinase 9 | H014820_01 | NM_002752 | 246857 | MAPK9 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.9883614 | 0.998 |
| 583 | nfatPathway_h | BioCarta | H000570_01 | Info | CREB binding protein (Rubinstein-Taybi syndrome) | H000570_01 | U47741 | 23598 | CREBBP | gene_regulation, transcription | 0.0048718 | 1.469 |
| 584 | nfatPathway_h | BioCarta | H003415_01 | Info | Protein kinase, cAMP-dependent, catalytic, beta | H003415_01 | M34181 | 87773 | PRKACB | Perou’s – Intrinsic – Breast-Cancer-Genes, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0048904 | 0.647 |
| 585 | nfatPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 586 | nfatPathway_h | BioCarta | H003006_01 | Info | Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 | H003006_01 | K02215 | 3697 | SERPINA8 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology | 0.0063778 | 1.296 |
| 587 | nfatPathway_h | BioCarta | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 588 | nfatPathway_h | BioCarta | H010817_01 | Info | Heart and neural crest derivatives expressed 2 | H010817_01 | AF087940 | 36029 | HAND2 | NFAT and Hypertrophy of the heart (Transcription in the broken heart) | 0.0143304 | 1.266 |
| 589 | nfatPathway_h | BioCarta | H003305_01 | Info | Ribosomal protein S6 kinase, 70kD, polypeptide 1 | H003305_01 | M60724 | 86858 | RPS6KB1 | CTCF: First Multivalent Nuclear Factor, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Rac 1 cell motility signaling pathway, Regulation of eIF4e and p70 S6 Kinase, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0214523 | 1.448 |
| 590 | nfatPathway_h | BioCarta | H002145_01 | Info | FK506-binding protein 1A (12kD) | H002145_01 | M34539 | 752 | FKBP1A | mTOR Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart) | 0.0298997 | 1.239 |
| 591 | nfatPathway_h | BioCarta | H001320_01 | Info | GATA-binding protein 4 | H001320_01 | L34357 | 243987 | GATA4 | ALK in cardiac myocytes, Hop Pathway in Cardiac Development, NFAT and Hypertrophy of the heart (Transcription in the broken heart), gene_regulation, misc, transcription | 0.0421967 | 0.782 |
| 592 | nfatPathway_h | BioCarta | H002194_01 | Info | Casein kinase 1, alpha 1 | H002194_01 | L37042 | 283738 | CSNK1A1 | Deregulation of CDK5 in Alzheimer’s Disease, Hypoxia and p53 in the Cardiovascular system, NFAT and Hypertrophy of the heart (Transcription in the broken heart), WNT Signaling Pathway, cell_cycle, cell_signaling, signal_transduction | 0.0461818 | 0.809 |
| 593 | nfatPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 594 | nfatPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 595 | nfatPathway_h | BioCarta | H001698_01 | Info | Protein kinase, cAMP-dependent, regulatory, type II, alpha | H001698_01 | X14968 | 289075 | PRKAR2A | AKAP95 role in mitosis and chromosome dynamics, Protein Kinase A at the Centrosome, Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation | 0.2569617 | 1.125 |
| 596 | nfatPathway_h | BioCarta | H012897_01 | Info | Myosin, heavy polypeptide 2, skeletal muscle, adult | H012897_01 | S73840 | 931 | MYH2 | NFAT and Hypertrophy of the heart (Transcription in the broken heart) | 0.3008555 | 0.888 |
| 597 | nfatPathway_h | BioCarta | H014455_01 | Info | Calreticulin | H014455_01 | NM_004343 | 16488 | CALR | NFAT and Hypertrophy of the heart (Transcription in the broken heart) | 0.3289938 | 0.903 |
| 598 | nfatPathway_h | BioCarta | H003511_01 | Info | Leukemia inhibitory factor (cholinergic differentiation factor) | H003511_01 | NM_002309 | 2250 | LIF | NFAT and Hypertrophy of the heart (Transcription in the broken heart), immunology | 0.3368076 | 0.897 |
| 599 | nfatPathway_h | BioCarta | H001979_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | H001979_01 | M29551 | 151531 | PPP3CB | cell_cycle, cell_signaling | 0.3386238 | 0.898 |
| 600 | nfatPathway_h | BioCarta | H000650_01 | Info | Glycogen synthase kinase 3 beta | H000650_01 | L33801 | 78802 | GSK3B | ALK in cardiac myocytes, Cell Cycle: G1/S Check Point , Deregulation of CDK5 in Alzheimer’s Disease, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Presenilin action in Notch and Wnt signaling, Regulation of eIF2, Segmentation Clock, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Sonic Hedgehog (Shh) Pathway, WNT Signaling Pathway, Phosphatidylinositol signaling system | 0.353328 | 1.118 |
| 601 | nfatPathway_h | BioCarta | H000645_01 | Info | Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | H000645_01 | M33336 | 183037 | PRKAR1A | Activation of cAMP-dependent protein kinase, PKA, cell_cycle, cell_signaling, signal_transduction | 0.4305614 | 0.935 |
| 602 | nfatPathway_h | BioCarta | H013229_01 | Info | Cardiac-specific homeo box | H013229_01 | U34962 | 54473 | CSX | ALK in cardiac myocytes | 0.4458316 | 1.087 |
| 603 | nfatPathway_h | BioCarta | H003578_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | H003578_01 | S46622 | 75206 | PPP3CC | 0.5197011 | 0.934 | |
| 604 | nfatPathway_h | BioCarta | H002045_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | H002045_01 | U80917 | 96149 | NFATC1 | BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology | 0.623508 | 1.051 |
| 605 | nfatPathway_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 | 71816 | AKT1 | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 606 | nfatPathway_h | BioCarta | H002427_01 | Info | Calcium/calmodulin-dependent protein kinase I | H002427_01 | L41816 | 184402 | CAMK1 | Actions of Nitric Oxide in the Heart, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Effects of calcineurin in Keratinocyte Differentiation, Endocytotic role of NDK, Phosphins and Dynamin, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Nitric Oxide Signaling Pathway, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of PGC-1a, Role of MEF2D in T-cell Apoptosis, Signal Dependent Regulation of Myogenesis by Corepressor MITR, Signaling Pathway from G-Protein Families, … | 0.6744118 | 1.052 |
| 607 | nfatPathway_h | BioCarta | H002470_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | H002470_01 | L41067 | 172674 | NFATC3 | immunology | 0.7190859 | 0.97 |
| 608 | nfatPathway_h | BioCarta | H010996_01 | Info | Heart and neural crest derivatives expressed 1 | H010996_01 | AF061756 | 152531 | HAND1 | NFAT and Hypertrophy of the heart (Transcription in the broken heart) | 0.7251839 | 0.966 |
| 609 | nfatPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 610 | nfatPathway_h | BioCarta | H002404_01 | Info | Synaptotagmin I | H002404_01 | M55047 | 154679 | SYT1 | 0.8170962 | 0.971 | |
| 611 | nfatPathway_h | BioCarta | H000579_01 | Info | Calmodulin 2 (phosphorylase kinase, delta) | H000579_01 | D45887 | 182278 | CALM2 | 0.9689776 | 1.004 | |
| 612 | il3Pathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 613 | il3Pathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 614 | il3Pathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 615 | il3Pathway_h | BioCarta | H002261_01 | Info | Signal transducer and activator of transcription 5B | H002261_01 | U47686 | 244613 | STAT5B | 0.441402 | 1.071 | |
| 616 | il3Pathway_h | BioCarta | H009068_01 | Info | Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) | H009068_01 | AL080218 | 24064 | 0.509279 | 1.056 | ||
| 617 | il3Pathway_h | BioCarta | H003501_01 | Info | Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | H003501_01 | M59941 | 285401 | CSF2RB | IL 3 signaling pathway, immunology | 0.683589 | 1.037 |
| 618 | il3Pathway_h | BioCarta | H003153_01 | Info | Interleukin 3 (colony-stimulating factor, multiple) | H003153_01 | M20137 | 694 | IL3 | Cytokine Network, Cytokines and Inflammatory Response, Dendritic cells in regulating TH1 and TH2 Development, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 3 signaling pathway, Regulation of BAD phosphorylation, Regulation of hematopoiesis by cytokines, The Role of Eosinophils in the Chemokine Network of Allergy, immunology | 0.7001094 | 1.037 |
| 619 | il3Pathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 620 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000375_01 | Info | ELK4, ETS-domain protein (SRF accessory protein 1) | H000375_01 | M85164 | 169241 | ELK4 | gene_regulation, transcription | 0.000821 | 0.552 |
| 621 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H003463_01 | Info | Spleen focus forming virus (SFFV) proviral integration oncogene spi1 | H003463_01 | X52056 | 157441 | SPI1 | tsonc | 0.0010958 | 1.855 |
| 622 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 623 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H001284_01 | Info | Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) | H001284_01 | L04731 | 199160 | MLL | misc | 0.0019854 | 0.707 |
| 624 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000316_01 | Info | Delta sleep inducing peptide, immunoreactor | H000316_01 | AL110191 | 75450 | DSIPI | 0.0102545 | 1.531 | |
| 625 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000370_01 | Info | Transcription factor binding to IGHM enhancer 3 | H000370_01 | AL161985 | 274184 | TFE3 | 0.0200243 | 1.264 | |
| 626 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H001315_01 | Info | Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | H001315_01 | D43968 | 129914 | RUNX1 | 0.0288879 | 0.822 | |
| 627 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000343_01 | Info | Early growth response 3 | H000343_01 | X63741 | 74088 | EGR3 | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, cell_signaling | 0.0317099 | 0.777 |
| 628 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H014573_01 | Info | Homo sapiens HSPC106 mRNA, partial CDS | H014573_01 | AF161369 | 187763 | How Progesterone Initiates the Oocyte Maturation | 0.0559133 | 0.793 | |
| 629 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000716_01 | Info | Nuclear receptor coactivator 3 | H000716_01 | AF012108 | 225977 | NCOA3 | Control of Gene Expression by Vitamin D Receptor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Transcription Regulation by Methyltransferase of CARM1 | 0.0573314 | 0.753 |
| 630 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H001476_01 | Info | Polyamine-modulated factor 1 | H001476_01 | AL080101 | 94446 | PMF1 | 0.0616383 | 0.814 | |
| 631 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000318_01 | Info | Ring finger protein 4 | H000318_01 | AB000468 | 66394 | RNF4 | 0.0636643 | 0.831 | |
| 632 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H013244_01 | Info | N-myc (and STAT) interactor | H013244_01 | U32849 | 54483 | NMI | IL-2 Receptor Beta Chain in T cell Activation, IL-7 Signal Transduction, signal_transduction | 0.0799702 | 1.269 |
| 633 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H002168_01 | Info | GATA-binding protein 2 | H002168_01 | M68891 | 760 | GATA2 | gene_regulation, misc, transcription | 0.0841754 | 0.806 |
| 634 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H009444_01 | Info | GTF2I repeat domain-containing 1 | H009444_01 | NM_016328 | 21075 | GTF2IRD1 | 0.0990864 | 0.84 | |
| 635 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H001313_01 | Info | Hematopoietically expressed homeobox | H001313_01 | L16499 | 118651 | HHEX | misc, transcription | 0.110793 | 1.2 |
| 636 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H006426_01 | Info | Transcriptional regulator protein | H006426_01 | AK002202 | 27299 | HCNGP | 0.1148626 | 0.866 | |
| 637 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H003249_01 | Info | V-ets avian erythroblastosis virus E26 oncogene homolog 1 | H003249_01 | X14798 | 248109 | ETS1 | Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc | 0.1428371 | 0.878 |
| 638 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 | 79070 | MYC | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 639 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H014806_01 | Info | DNA (cytosine-5-)-methyltransferase 3 alpha | H014806_01 | NM_022552 | 241565 | DNMT3A | Methionine metabolism | 0.1805543 | 1.16 |
| 640 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000147_01 | Info | TG-interacting factor (TALE family homeobox) | H000147_01 | X89750 | 90077 | TGIF | 0.213685 | 0.86 | |
| 641 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H004003_01 | Info | FBJ murine osteosarcoma viral oncogene homolog B | H004003_01 | L49169 | 75678 | FOSB | FOSB gene expression and drug abuse, immunology, tsonc | 0.2326486 | 1.128 |
| 642 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H009897_01 | Info | Ring finger protein 14 | H009897_01 | AB022663 | 215857 | RNF14 | 0.2702283 | 0.871 | |
| 643 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H007149_01 | Info | SRY (sex determining region Y)-box 13 | H007149_01 | AF083105 | 201671 | SOX13 | 0.3124097 | 1.096 | |
| 644 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H009485_01 | Info | Zinc finger protein 220 | H009485_01 | U47742 | 82210 | ZNF220 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.3321862 | 1.126 |
| 645 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H005858_01 | Info | GLI-Kruppel family member HKR3 | H005858_01 | NM_005341 | 2364 | HKR3 | tsonc | 0.3984807 | 1.092 |
| 646 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H003529_01 | Info | ELK3, ETS-domain protein (SRF accessory protein 2) | H003529_01 | Z36715 | 121529 | ELK3 | tsonc | 0.4403881 | 0.913 |
| 647 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H002830_01 | Info | Spi-B transcription factor (Spi-1/PU.1 related) | H002830_01 | X66079 | 192861 | SPIB | gene_regulation, transcription | 0.4694779 | 1.107 |
| 648 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H006672_01 | Info | Regulatory factor X-associated ankyrin containing protein | H006672_01 | AF094760 | 296776 | RFXANK | 0.5074495 | 0.935 | |
| 649 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H013862_01 | Info | Prospero-related homeobox 1 | H013862_01 | U44060 | 159437 | PROX1 | 0.5310492 | 1.091 | |
| 650 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000780_01 | Info | Nuclear receptor subfamily 1, group H, member 3 | H000780_01 | U22662 | 81336 | NR1H3 | FXR and LXR Regulation of Cholesterol Metabolism, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity | 0.578592 | 1.089 |
| 651 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H010945_01 | Info | Bromodomain adjacent to zinc finger domain, 1B | H010945_01 | AF072810 | 194688 | BAZ1B | 0.6010528 | 0.956 | |
| 652 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H011149_01 | Info | Ring-box 1 | H011149_01 | NM_014248 | 279919 | RBX1 | ER associated degradation (ERAD) Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression | 0.603709 | 1.055 |
| 653 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H009346_01 | Info | AML1 | H009346_01 | S76346 | 166060 | 0.6048212 | 1.054 | ||
| 654 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H005868_01 | Info | Speckle-type POZ protein | H005868_01 | AJ000644 | 129951 | SPOP | 0.6154454 | 1.066 | |
| 655 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H004156_01 | Info | Sirtuin (silent mating type information regulation 2, S. cerevisiae, homolog) 2 | H004156_01 | NM_012237 | 44017 | SIRT2 | 0.6844495 | 0.961 | |
| 656 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H016647_01 | Info | Hypothetical protein FLJ22263 similar to nuclear receptor-binding SET-domain protein 1 | H016647_01 | NM_022455 | 99010 | FLJ22263 | Lysine degradation | 0.7870953 | 1.027 |
| 657 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000578_01 | Info | Histone deacetylase 1 | H000578_01 | D50405 | 88556 | HDAC1 | immunology | 0.8155423 | 1.017 |
| 658 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000060_01 | Info | Polyglutamine binding protein 1 | H000060_01 | AJ005893 | 30570 | PQBP1 | 0.824418 | 0.98 | |
| 659 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000554_01 | Info | Nuclear antigen Sp100 | H000554_01 | AF056322 | 77617 | SP100 | Regulation of transcriptional activity by PML, gene_regulation, transcription | 0.8369981 | 0.979 |
| 660 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H007065_01 | Info | Growth factor independent 1 | H007065_01 | U67369 | 73172 | GFI1 | immunology | 0.8418068 | 0.979 |
| 661 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 662 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000647_01 | Info | E74-like factor 1 (ets domain transcription factor) | H000647_01 | M82882 | 154365 | ELF1 | gene_regulation, transcription | 0.879249 | 1.014 |
| 663 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H000083_01 | Info | H2A histone family, member Z | H000083_01 | M37583 | 119192 | H2AFZ | 0.8912337 | 0.987 | |
| 664 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H015533_01 | Info | Hypothetical protein FLJ22191 | H015533_01 | NM_025231 | 288539 | FLJ22191 | 0.9459425 | 1.008 | |
| 665 | FETAL_LIVER_HS_ENRICHED_TF_JP_h | Manually Curated | H009837_01 | Info | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 | H009837_01 | U66617 | 79335 | SMARCD1 | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Control of Gene Expression by Vitamin D Receptor, development | 0.9574513 | 0.995 |
| 666 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 667 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 668 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 669 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 670 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H002261_01 | Info | Signal transducer and activator of transcription 5B | H002261_01 | U47686 | 244613 | STAT5B | 0.441402 | 1.071 | |
| 671 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H003371_01 | Info | Erythropoietin receptor | H003371_01 | NM_000121 | 89548 | EPOR | Perou’s – Intrinsic – Breast-Cancer-Genes, EPO Signaling Pathway, Erythropoietin mediated neuroprotection through NF-kB, immunology | 0.4485722 | 0.93 |
| 672 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H009068_01 | Info | Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) | H009068_01 | AL080218 | 24064 | 0.509279 | 1.056 | ||
| 673 | epoPathway_h | Erythropoietin, which activates the MAPK pathway, stimulates erythrocyte production and is an effective treatment for anemia. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 674 | nthiPathway_h | BioCarta | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 675 | nthiPathway_h | BioCarta | H000570_01 | Info | CREB binding protein (Rubinstein-Taybi syndrome) | H000570_01 | U47741 | 23598 | CREBBP | gene_regulation, transcription | 0.0048718 | 1.469 |
| 676 | nthiPathway_h | BioCarta | H003232_01 | Info | Mitogen-activated protein kinase kinase kinase 14 | H003232_01 | Y10256 | 47007 | MAP3K14 | CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.005309 | 0.755 |
| 677 | nthiPathway_h | BioCarta | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 678 | nthiPathway_h | BioCarta | H002944_01 | Info | Interleukin 8 | H002944_01 | M17017 | 624 | IL8 | Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology | 0.0100881 | 0.681 |
| 679 | nthiPathway_h | BioCarta | H000657_01 | Info | Myeloid differentiation primary response gene (88) | H000657_01 | U70451 | 82116 | MYD88 | Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, Toll-Like Receptor Pathway, apoptosis, immunology, misc | 0.0732203 | 1.23 |
| 680 | nthiPathway_h | BioCarta | H000598_01 | Info | Human glucocorticoid receptor alpha mRNA, variant 3′ UTR | H000598_01 | U25029 | 102761 | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Corticosteroids and cardioprotection, NFkB activation by Nontypeable Hemophilus influenzae, Visceral Fat Deposits and the Metabolic Syndrome | 0.2214106 | 1.108 | |
| 681 | nthiPathway_h | BioCarta | H002700_01 | Info | Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) | H002700_01 | L11695 | 220 | TGFBR1 | ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development | 0.3279632 | 0.903 |
| 682 | nthiPathway_h | BioCarta | H001957_01 | Info | Interleukin 1, beta | H001957_01 | M15330 | 126256 | IL1B | IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology | 0.4390274 | 1.089 |
| 683 | nthiPathway_h | BioCarta | H003434_01 | Info | Dual specificity phosphatase 1 | H003434_01 | NM_004417 | 171695 | DUSP1 | CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway | 0.8183145 | 0.968 |
| 684 | nthiPathway_h | BioCarta | H002447_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | H002447_01 | M69043 | 81328 | NFKBIA | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … | 0.8245205 | 0.975 |
| 685 | nthiPathway_h | BioCarta | H001376_01 | Info | Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) | H001376_01 | AL133012 | 306440 | Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction | 0.8639394 | 0.98 | |
| 686 | nthiPathway_h | BioCarta | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 687 | nthiPathway_h | BioCarta | H003151_01 | Info | E1A binding protein p300 | H003151_01 | U01877 | 25272 | EP300 | Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription | 0.9607239 | 1.004 |
| 688 | nthiPathway_h | BioCarta | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 689 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H003124_01 | Info | Fc fragment of IgG, receptor, transporter, alpha | H003124_01 | U12255 | 111903 | FCGRT | 2.86e-05 | 1.917 | |
| 690 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H000825_01 | Info | S100 calcium-binding protein A8 (calgranulin A) | H000825_01 | X06234 | 100000 | S100A8 | immunology | 0.0001788 | 2.746 |
| 691 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H002406_01 | Info | Jun B proto-oncogene | H002406_01 | X51345 | 198951 | JUNB | GATA3 participate in activating the Th2 cytokine genes expression, tsonc | 0.0021761 | 1.408 |
| 692 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H002878_01 | Info | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog | H002878_01 | M16038 | 80887 | LYN | BCR Signaling Pathway, Eph Kinases and ephrins support platelet aggregation, Fc Epsilon Receptor I Signaling in Mast Cells, Phosphoinositides and their downstream targets., immunology, signal_transduction, tsonc | 0.0068841 | 1.545 |
| 693 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H000316_01 | Info | Delta sleep inducing peptide, immunoreactor | H000316_01 | AL110191 | 75450 | DSIPI | 0.0102545 | 1.531 | |
| 694 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H006355_01 | Info | KIAA1451 protein | H006355_01 | AL049923 | 109694 | KIAA1451 | 0.0105169 | 1.369 | |
| 695 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H000199_01 | Info | Translocated promoter region (to activated MET oncogene) | H000199_01 | X66397 | 169750 | TPR | tsonc | 0.036441 | 0.801 |
| 696 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H001971_01 | Info | Retinoblastoma-binding protein 6 | H001971_01 | X85133 | 85273 | RBBP6 | 0.0366619 | 0.747 | |
| 697 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H006255_01 | Info | Syndecan binding protein (syntenin) | H006255_01 | AF000652 | 8180 | SDCBP | 0.0567867 | 1.234 | |
| 698 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H002168_01 | Info | GATA-binding protein 2 | H002168_01 | M68891 | 760 | GATA2 | gene_regulation, misc, transcription | 0.0841754 | 0.806 |
| 699 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H004936_01 | Info | DKFZP564A122 protein | H004936_01 | AL110269 | 187991 | DKFZP564A122 | 0.0852946 | 1.175 | |
| 700 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H007504_01 | Info | Hemoglobin, epsilon 1 | H007504_01 | NM_005330 | 117848 | HBE1 | 0.118007 | 0.749 | |
| 701 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 | 79070 | MYC | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 702 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H001023_01 | Info | Mannosidase, alpha, class 2A, member 2 | H001023_01 | L28821 | 295605 | MAN2A2 | ER associated degradation (ERAD) Pathway, Steps in the Glycosylation of Mammalian N-linked Oligosaccharides, N-Glycan biosynthesis | 0.2111813 | 1.139 |
| 703 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H003255_01 | Info | CDC37 (cell division cycle 37, S. cerevisiae, homolog) | H003255_01 | U43077 | 160958 | CDC37 | 0.2178008 | 0.878 | |
| 704 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H000068_01 | Info | Signal recognition particle 72kD | H000068_01 | AF069765 | 237825 | SRP72 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.2609516 | 0.897 |
| 705 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H012741_01 | Info | Glutaredoxin (thioltransferase) | H012741_01 | AF069668 | 28988 | GLRX | pharmacology | 0.2704585 | 1.145 |
| 706 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H006807_01 | Info | Cytokine inducible SH2-containing protein | H006807_01 | AF132297 | 8257 | CISH | Growth Hormone Signaling Pathway, IL-2 Receptor Beta Chain in T cell Activation, immunology | 0.3746206 | 0.888 |
| 707 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H004864_01 | Info | Ubiquitin specific protease 1 | H004864_01 | AF117386 | 35086 | USP1 | 0.3871195 | 0.908 | |
| 708 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H006584_01 | Info | Splicing factor, arginine/serine-rich 11 | H006584_01 | M74002 | 11482 | SFRS11 | 0.4576641 | 1.062 | |
| 709 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H010826_01 | Info | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | H010826_01 | AB024334 | 25001 | YWHAG | 0.6175419 | 1.047 | |
| 710 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H016588_01 | Info | Hypothetical protein DKFZp761B2423 | H016588_01 | AK026954 | 91065 | DKFZp761B2423 | 0.6339659 | 1.046 | |
| 711 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H010792_01 | Info | Dynein, cytoplasmic, light intermediate polypeptide 2 | H010792_01 | AF035812 | 194625 | DNCLI2 | 0.6511108 | 1.058 | |
| 712 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H002850_01 | Info | Murine leukemia viral (bmi-1) oncogene homolog | H002850_01 | L13689 | 431 | BMI1 | Perou’s – Intrinsic – Breast-Cancer-Genes, The PRC2 Complex Sets Long-term Gene Silencing Through Modification of Histone Tails, immunology, tsonc | 0.7846354 | 0.976 |
| 713 | HOXA9_DOWN_h | Dorsam_et_al_2004 | H003618_01 | Info | Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) | H003618_01 | D17547 | 301865 | DCT | Tyrosine metabolism | 0.9648525 | 0.996 |
| 714 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 715 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H000514_01 | Info | Neutrophil cytosolic factor 1 (47kD, chronic granulomatous disease, autosomal 1) | H000514_01 | M55067 | 1583 | NCF1 | immunology | 0.0060162 | 1.915 |
| 716 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 717 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 718 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 719 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 720 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 721 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 | 72241 | MAP2K2 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 722 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H001979_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | H001979_01 | M29551 | 151531 | PPP3CB | cell_cycle, cell_signaling | 0.3386238 | 0.898 |
| 723 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H010976_01 | Info | Guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | H010976_01 | M63904 | 73797 | GNA15 | 0.4609468 | 0.929 | |
| 724 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H003578_01 | Info | Protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | H003578_01 | S46622 | 75206 | PPP3CC | 0.5197011 | 0.934 | |
| 725 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002045_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | H002045_01 | U80917 | 96149 | NFATC1 | BCR Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Effects of calcineurin in Keratinocyte Differentiation, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of MEF2D in T-cell Apoptosis, Signaling Pathway from G-Protein Families, T Cell Receptor Signaling Pathway, immunology | 0.623508 | 1.051 |
| 726 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002427_01 | Info | Calcium/calmodulin-dependent protein kinase I | H002427_01 | L41816 | 184402 | CAMK1 | Actions of Nitric Oxide in the Heart, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Ca++/ Calmodulin-dependent Protein Kinase Activation, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Effects of calcineurin in Keratinocyte Differentiation, Endocytotic role of NDK, Phosphins and Dynamin, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Nitric Oxide Signaling Pathway, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of PGC-1a, Role of MEF2D in T-cell Apoptosis, Signal Dependent Regulation of Myogenesis by Corepressor MITR, Signaling Pathway from G-Protein Families, … | 0.6744118 | 1.052 |
| 727 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002470_01 | Info | Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | H002470_01 | L41067 | 172674 | NFATC3 | immunology | 0.7190859 | 0.97 |
| 728 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 729 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002404_01 | Info | Synaptotagmin I | H002404_01 | M55047 | 154679 | SYT1 | 0.8170962 | 0.971 | |
| 730 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002447_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | H002447_01 | M69043 | 81328 | NFKBIA | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … | 0.8245205 | 0.975 |
| 731 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 732 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H000579_01 | Info | Calmodulin 2 (phosphorylase kinase, delta) | H000579_01 | D45887 | 182278 | CALM2 | 0.9689776 | 1.004 | |
| 733 | fmlppathway_h | The fMLP receptor is a G-protein coupled receptor in neutrophiles that recognizes formylated bacterial peptides and activates NADPH oxidase. | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 734 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002040_01 | Info | Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) | H002040_01 | X00588 | 77432 | EGFR | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc | 0.0004362 | 0.669 |
| 735 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 736 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 737 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H003006_01 | Info | Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8 | H003006_01 | K02215 | 3697 | SERPINA8 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Angiotensin-converting enzyme 2 regulates heart function, Bioactive Peptide Induced Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, immunology | 0.0063778 | 1.296 |
| 738 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002573_01 | Info | Protein tyrosine kinase 2 beta | H002573_01 | U43522 | 20313 | PTK2B | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CXCR4 Signaling Pathway, IL-7 Signal Transduction, Ion Channel and Phorbol Esters Signaling Pathway, Links between Pyk2 and Map Kinases, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Thrombin signaling and protease-activated receptors, angiogenesis, immunology, signal_transduction | 0.0091935 | 1.367 |
| 739 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 740 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H003493_01 | Info | MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B) | H003493_01 | X63380 | 78881 | MEF2B | 0.0145042 | 1.328 | |
| 741 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H001992_01 | Info | Activating transcription factor 2 | H001992_01 | X15875 | 198166 | ATF2 | ALK in cardiac myocytes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , The 4-1BB-dependent immune response, The information-processing pathway at the IFN-beta enhancer | 0.0178377 | 0.749 |
| 742 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H001365_01 | Info | Protein kinase C, beta 1 | H001365_01 | X07109 | 77202 | PRKCB1 | Bioactive Peptide Induced Signaling Pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Ion Channel and Phorbol Esters Signaling Pathway, T Cell Receptor Signaling Pathway, Phosphatidylinositol signaling system, angiogenesis, cell_cycle, cell_signaling, signal_transduction | 0.0304335 | 1.379 |
| 743 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 744 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 745 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 746 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 747 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002112_01 | Info | PTK2 protein tyrosine kinase 2 | H002112_01 | L13616 | 740 | PTK2 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Apoptotic Signaling in Response to DNA Damage, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, CCR3 signaling in Eosinophils, Cell to Cell Adhesion Signaling, CXCR4 Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, HIV-I Nef: negative effector of Fas and TNF, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, VEGF, Hypoxia, and Angiogenesis, angiogenesis, signal_transduction | 0.2346929 | 0.896 |
| 748 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 | 72241 | MAP2K2 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 749 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H011336_01 | Info | Guanine nucleotide binding protein (G protein), q polypeptide | H011336_01 | U43083 | 296261 | GNAQ | Activation of PKC through G protein coupled receptor, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CCR3 signaling in Eosinophils, CXCR4 Signaling Pathway, Effects of calcineurin in Keratinocyte Differentiation, G-Protein Signaling Through Tubby Proteins, Links between Pyk2 and Map Kinases, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase, Signaling Pathway from G-Protein Families, Thrombin signaling and protease-activated receptors, immunology | 0.3713616 | 0.89 |
| 750 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 751 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H002404_01 | Info | Synaptotagmin I | H002404_01 | M55047 | 154679 | SYT1 | 0.8170962 | 0.971 | |
| 752 | at1rPathway_h | Binding of angiotensin II to AT1-R activates Ca2+ signaling and the JNK pathway. | H000579_01 | Info | Calmodulin 2 (phosphorylase kinase, delta) | H000579_01 | D45887 | 182278 | CALM2 | 0.9689776 | 1.004 | |
| 753 | tumor_supressor_h | BioCarta | H001935_01 | Info | Glyceraldehyde-3-phosphate dehydrogenase | H001935_01 | U34995 | 169476 | GAPD | 0.0001082 | 1.485 | |
| 754 | tumor_supressor_h | BioCarta | H003112_01 | Info | Retinoblastoma 1 (including osteosarcoma) | H003112_01 | L41870 | 75770 | RB1 | BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0008596 | 0.674 |
| 755 | tumor_supressor_h | BioCarta | H002387_01 | Info | MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1) | H002387_01 | NM_000251 | 78934 | MSH2 | DNA_damage, tsonc | 0.004273 | 0.694 |
| 756 | tumor_supressor_h | BioCarta | H000570_01 | Info | CREB binding protein (Rubinstein-Taybi syndrome) | H000570_01 | U47741 | 23598 | CREBBP | gene_regulation, transcription | 0.0048718 | 1.469 |
| 757 | tumor_supressor_h | BioCarta | H000208_01 | Info | Breast cancer 1, early onset | H000208_01 | NM_007295 | 194143 | BRCA1 | ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc | 0.009032 | 0.746 |
| 758 | tumor_supressor_h | BioCarta | H002789_01 | Info | Tumor protein p53 (Li-Fraumeni syndrome) | H002789_01 | NM_000546 | 1846 | TP53 | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc | 0.0273242 | 1.207 |
| 759 | tumor_supressor_h | BioCarta | H003759_01 | Info | Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | H003759_01 | U40343 | 29656 | CDKN2D | Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation | 0.0311312 | 1.253 |
| 760 | tumor_supressor_h | BioCarta | H002114_01 | Info | Neurofibromin 2 (bilateral acoustic neuroma) | H002114_01 | L11353 | 902 | NF2 | immunology, tsonc | 0.2904249 | 0.837 |
| 761 | tumor_supressor_h | BioCarta | H002700_01 | Info | Transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD) | H002700_01 | L11695 | 220 | TGFBR1 | ALK in cardiac myocytes, Function of SLRP in Bone: An Integrated View, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, p38 MAPK Signaling Pathway , TGF beta signaling pathway, Phosphatidylinositol signaling system, angiogenesis, development | 0.3279632 | 0.903 |
| 762 | tumor_supressor_h | BioCarta | H002611_01 | Info | Interferon regulatory factor 1 | H002611_01 | X14454 | 80645 | IRF1 | gene_regulation, transcription | 0.3284273 | 0.915 |
| 763 | tumor_supressor_h | BioCarta | H006635_01 | Info | Homo sapiens clone 23607 mRNA sequence | H006635_01 | AF038181 | 167825 | ALK in cardiac myocytes, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Multi-step Regulation of Transcription by Pitx2, Presenilin action in Notch and Wnt signaling, TGF beta signaling pathway, WNT Signaling Pathway, development, immunology, tsonc | 0.6181322 | 1.041 | |
| 764 | tumor_supressor_h | BioCarta | H003538_01 | Info | Actin, beta | H003538_01 | NM_001101 | 288061 | ACTB | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes | 0.6253266 | 0.956 |
| 765 | tumor_supressor_h | BioCarta | H007492_01 | Info | Cofilin 1 (non-muscle) | H007492_01 | X95404 | 180370 | CFL1 | CCR3 signaling in Eosinophils, Rac 1 cell motility signaling pathway, Rho cell motility signaling pathway | 0.685636 | 1.038 |
| 766 | tumor_supressor_h | BioCarta | H003594_01 | Info | Cyclin-dependent kinase inhibitor 1C (p57, Kip2) | H003594_01 | U22398 | 106070 | CDKN1C | cell_cycle, immunology, tsonc | 0.7532847 | 0.968 |
| 767 | tumor_supressor_h | BioCarta | H003151_01 | Info | E1A binding protein p300 | H003151_01 | U01877 | 25272 | EP300 | Acetylation and Deacetylation of RelA in The Nucleus, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Control of Gene Expression by Vitamin D Receptor, Hypoxia and p53 in the Cardiovascular system, Hypoxia-Inducible Factor in the Cardiovascular System, IL-7 Signal Transduction, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Melanocyte Development and Pigmentation Pathway, Multi-step Regulation of Transcription by Pitx2, NFkB activation by Nontypeable Hemophilus influenzae, Pelp1 Modulation of Estrogen Receptor Activity, Role of ERBB2 in Signal Transduction and Oncology, Role of MEF2D in T-cell Apoptosis, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, TGF beta signaling pathway, Transcription Regulation by Methyltransferase of CARM1, gene_regulation, transcription | 0.9607239 | 1.004 |
| 768 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002927_01 | Info | Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 | H002927_01 | Y00630 | 75716 | SERPINB2 | Fibrinolysis Pathway | 8.72e-05 | 0.627 |
| 769 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001857_01 | Info | ATP-binding cassette, sub-family B (MDR/TAP), member 2 | H001857_01 | X57522 | 158164 | ABCB2 | Perou’s – Intrinsic – Breast-Cancer-Genes, Antigen Processing and Presentation, cell_signaling, immunology, misc, pharmacology | 0.0004469 | 1.641 |
| 770 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 771 | NFKB_INDUCED_h | Hinata_et_al_2003 | H000438_01 | Info | CASP8 and FADD-like apoptosis regulator | H000438_01 | Y14039 | 195175 | CFLAR | FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, IL-2 Receptor Beta Chain in T cell Activation, Induction of apoptosis through DR3 and DR4/5 Death Receptors | 0.00266 | 1.745 |
| 772 | NFKB_INDUCED_h | Hinata_et_al_2003 | H010080_01 | Info | Homo sapiens mRNA; cDNA DKFZp564M0264 (from clone DKFZp564M0264) | H010080_01 | AL117621 | 180777 | 0.0054124 | 1.799 | ||
| 773 | NFKB_INDUCED_h | Hinata_et_al_2003 | H000649_01 | Info | Proline-rich protein with nuclear targeting signal | H000649_01 | U03105 | 75969 | B4-2 | 0.0061172 | 1.332 | |
| 774 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002671_01 | Info | Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | H002671_01 | X15357 | 167382 | NPR1 | Purine metabolism | 0.0065717 | 0.774 |
| 775 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002944_01 | Info | Interleukin 8 | H002944_01 | M17017 | 624 | IL8 | Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Free Radical Induced Apoptosis, IL 17 Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Proepithelin Conversion to Epithelin and Wound Repair Control, Regulation of hematopoiesis by cytokines, immunology | 0.0100881 | 0.681 |
| 776 | NFKB_INDUCED_h | Hinata_et_al_2003 | H008666_01 | Info | Tumor necrosis factor, alpha-induced protein 2 | H008666_01 | M92357 | 101382 | TNFAIP2 | immunology | 0.0141217 | 1.495 |
| 777 | NFKB_INDUCED_h | Hinata_et_al_2003 | H013461_01 | Info | Nef-associated factor 1 | H013461_01 | AJ011895 | 109281 | NAF1 | 0.0170206 | 1.321 | |
| 778 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001630_01 | Info | Adaptor-related protein complex 2, beta 1 subunit | H001630_01 | M34175 | 74626 | AP2B1 | 0.0220385 | 1.231 | |
| 779 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002243_01 | Info | Ras homolog gene family, member E | H002243_01 | S82240 | 6838 | ARHE | immunology | 0.032366 | 1.421 |
| 780 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002149_01 | Info | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | H002149_01 | U03106 | 179665 | CDKN1A | ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc | 0.0349766 | 1.236 |
| 781 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002371_01 | Info | Cyclin B1 | H002371_01 | M25753 | 23960 | CCNB1 | Activation of Src by Protein-tyrosine phosphatase alpha, AKAP95 role in mitosis and chromosome dynamics, Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, How Progesterone Initiates the Oocyte Maturation, Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle, Stathmin and breast cancer resistance to antimicrotubule agents, cell_cycle | 0.037756 | 0.797 |
| 782 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001462_01 | Info | Homo sapiens cDNA FLJ11941 fis, clone HEMBB1000649 | H001462_01 | AK000942 | 124106 | 0.0396409 | 0.834 | ||
| 783 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003156_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide | H003156_01 | M83221 | 858 | RELB | tsonc | 0.0527226 | 1.209 |
| 784 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002381_01 | Info | CD9 antigen (p24) | H002381_01 | M38690 | 1244 | CD9 | angiogenesis, metastasis | 0.0657959 | 0.78 |
| 785 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002151_01 | Info | Replication protein A2 (32kD) | H002151_01 | J05249 | 79411 | RPA2 | DNA_replication | 0.0882481 | 0.865 |
| 786 | NFKB_INDUCED_h | Hinata_et_al_2003 | H012840_01 | Info | TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56 | H012840_01 | U51334 | 66772 | TAF2N | 0.0908377 | 0.855 | |
| 787 | NFKB_INDUCED_h | Hinata_et_al_2003 | H016047_01 | Info | Superoxide dismutase 2, mitochondrial | H016047_01 | NM_000636 | 318885 | SOD2 | Erythropoietin mediated neuroprotection through NF-kB, immunology, pharmacology | 0.0970832 | 1.313 |
| 788 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002937_01 | Info | Fibronectin 1 | H002937_01 | X02761 | 287820 | FN1 | angiogenesis, cell_signaling, immunology, metastasis | 0.128354 | 1.194 |
| 789 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003382_01 | Info | BCL2-related protein A1 | H003382_01 | Y09397 | 227817 | BCL2A1 | apoptosis, immunology | 0.1341711 | 1.195 |
| 790 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003249_01 | Info | V-ets avian erythroblastosis virus E26 oncogene homolog 1 | H003249_01 | X14798 | 248109 | ETS1 | Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc | 0.1428371 | 0.878 |
| 791 | NFKB_INDUCED_h | Hinata_et_al_2003 | H000433_01 | Info | Guanylate binding protein 1, interferon-inducible, 67kD | H000433_01 | M55542 | 62661 | GBP1 | cell_signaling | 0.1588062 | 1.172 |
| 792 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002107_01 | Info | Matrix metalloproteinase 9 (gelatinase B, 92kD gelatinase, 92kD type IV collagenase) | H002107_01 | J05070 | 151738 | MMP9 | Inhibition of Matrix Metalloproteinases, angiogenesis, immunology | 0.158933 | 1.438 |
| 793 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003550_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | H003550_01 | S76638 | 73090 | NFKB2 | gene_regulation, immunology, transcription, tsonc | 0.1593331 | 1.165 |
| 794 | NFKB_INDUCED_h | Hinata_et_al_2003 | H010496_01 | Info | Spectrin, beta, non-erythrocytic 1 | H010496_01 | AJ005694 | 107164 | SPTBN1 | Synaptic Proteins at the Synaptic Junction | 0.1646123 | 1.14 |
| 795 | NFKB_INDUCED_h | Hinata_et_al_2003 | H010713_01 | Info | SEC24 (S. cerevisiae) related gene family, member A | H010713_01 | AJ131244 | 211612 | SEC24A | 0.1754982 | 1.137 | |
| 796 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003810_01 | Info | Superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | H003810_01 | X02317 | 75428 | SOD1 | Cardiac Protection Against ROS , Free Radical Induced Apoptosis, immunology, pharmacology | 0.1871555 | 1.13 |
| 797 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 798 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001905_01 | Info | LPS-induced TNF-alpha factor | H001905_01 | NM_004862 | 76507 | PIG7 | 0.2026162 | 1.209 | |
| 799 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002591_01 | Info | General transcription factor IIH, polypeptide 4 (52kD subunit) | H002591_01 | Y07595 | 102910 | GTF2H4 | 0.2232784 | 0.812 | |
| 800 | NFKB_INDUCED_h | Hinata_et_al_2003 | H010732_01 | Info | A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 | H010732_01 | AB002364 | 27916 | ADAMTS3 | 0.2368079 | 0.872 | |
| 801 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002727_01 | Info | Matrix metalloproteinase 14 (membrane-inserted) | H002727_01 | Z48481 | 2399 | MMP14 | Perou’s – Intrinsic – Breast-Cancer-Genes, Inhibition of Matrix Metalloproteinases, immunology | 0.2434161 | 0.916 |
| 802 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002460_01 | Info | Plasminogen activator, tissue | H002460_01 | M15518 | 274404 | PLAT | Perou’s – Intrinsic – Breast-Cancer-Genes, Acute Myocardial Infarction, Fibrinolysis Pathway, Platelet Amyloid Precursor Protein Pathway, immunology | 0.3044479 | 0.927 |
| 803 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002553_01 | Info | Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), | H002553_01 | M14083 | 82085 | SERPINE1 | Fibrinolysis Pathway, Platelet Amyloid Precursor Protein Pathway | 0.3225313 | 0.914 |
| 804 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002611_01 | Info | Interferon regulatory factor 1 | H002611_01 | X14454 | 80645 | IRF1 | gene_regulation, transcription | 0.3284273 | 0.915 |
| 805 | NFKB_INDUCED_h | Hinata_et_al_2003 | H008736_01 | Info | Human clone 23612 mRNA sequence | H008736_01 | U90902 | 82141 | cell_signaling, signal_transduction, tsonc | 0.3721668 | 1.128 | |
| 806 | NFKB_INDUCED_h | Hinata_et_al_2003 | H005970_01 | Info | Butyrophilin, subfamily 3, member A3 | H005970_01 | U90548 | 167741 | BTN3A3 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.4000193 | 1.093 |
| 807 | NFKB_INDUCED_h | Hinata_et_al_2003 | H005605_01 | Info | Endothelial cell-specific molecule 1 | H005605_01 | X89426 | 41716 | ESM1 | 0.4029274 | 0.924 | |
| 808 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001957_01 | Info | Interleukin 1, beta | H001957_01 | M15330 | 126256 | IL1B | IL 5 Signaling Pathway, Msp/Ron Receptor Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, immunology | 0.4390274 | 1.089 |
| 809 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002617_01 | Info | GRO3 oncogene | H002617_01 | M36821 | 89690 | GRO3 | 0.4549631 | 0.919 | |
| 810 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003784_01 | Info | Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | H003784_01 | M24283 | 168383 | ICAM1 | Adhesion and Diapedesis of Granulocytes, Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, B Lymphocyte Cell Surface Molecules, Cells and Molecules involved in local acute inflammatory response, CTL mediated immune response against target cells , Monocyte and its Surface Molecules, Neutrophil and Its Surface Molecules, T Cytotoxic Cell Surface Molecules, T Helper Cell Surface Molecules, cell_signaling, immunology, metastasis | 0.4642919 | 0.93 |
| 811 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002294_01 | Info | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | H002294_01 | X78338 | 89433 | ABCC1 | Multi-Drug Resistance Factors | 0.4691659 | 0.928 |
| 812 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001215_01 | Info | Pentaxin-related gene, rapidly induced by IL-1 beta | H001215_01 | M31166 | 2050 | PTX3 | cell_cycle, cell_signaling, immunology | 0.5618599 | 0.929 |
| 813 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003496_01 | Info | Small inducible cytokine subfamily B (Cys-X-Cys), member 10 | H003496_01 | X02530 | 2248 | SCYB10 | 0.572348 | 1.053 | |
| 814 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003454_01 | Info | Integrin, beta 6 | H003454_01 | M35198 | 123125 | ITGB6 | immunology | 0.6028747 | 1.064 |
| 815 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001310_01 | Info | Natural killer cell transcript 4 | H001310_01 | M59807 | 943 | NK4 | 0.6125553 | 1.066 | |
| 816 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001133_01 | Info | Epididymis-specific, whey-acidic protein type, four-disulfide core; putative ovarian carcinoma marker | H001133_01 | X63187 | 2719 | HE4 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.6153965 | 0.937 |
| 817 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003110_01 | Info | Interleukin 6 (interferon, beta 2) | H003110_01 | X04430 | 93913 | IL6 | Cells and Molecules involved in local acute inflammatory response, Cytokine Network, Cytokines and Inflammatory Response, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, IL 5 Signaling Pathway, IL 6 signaling pathway, IL-10 Anti-inflammatory Signaling Pathway, Low-density lipoprotein (LDL) pathway during atherogenesis, Regulation of hematopoiesis by cytokines, Role of ERBB2 in Signal Transduction and Oncology, Signal transduction through IL1R, immunology | 0.680804 | 1.036 |
| 818 | NFKB_INDUCED_h | Hinata_et_al_2003 | H001975_01 | Info | Rho GDP dissociation inhibitor (GDI) beta | H001975_01 | L20688 | 83656 | ARHGDIB | Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, cell_signaling, misc, signal_transduction | 0.7369181 | 1.046 |
| 819 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003772_01 | Info | Xeroderma pigmentosum, complementation group C | H003772_01 | D21089 | 320 | XPC | DNA_damage, immunology | 0.7950726 | 0.977 |
| 820 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003015_01 | Info | Excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes over | H003015_01 | M13194 | 59544 | ERCC1 | DNA_damage, DNA_replication, immunology | 0.8177868 | 1.024 |
| 821 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003687_01 | Info | T-cell lymphoma invasion and metastasis 1 | H003687_01 | U16296 | 115176 | TIAM1 | cell_signaling, signal_transduction, tsonc | 0.8406417 | 1.019 |
| 822 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002490_01 | Info | Hexabrachion (tenascin C, cytotactin) | H002490_01 | X78565 | 289114 | HXB | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.856155 | 0.983 |
| 823 | NFKB_INDUCED_h | Hinata_et_al_2003 | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 824 | NFKB_INDUCED_h | Hinata_et_al_2003 | H013445_01 | Info | Rabaptin-5 | H013445_01 | X77723 | 326056 | RAB5EP | 0.8712741 | 0.984 | |
| 825 | NFKB_INDUCED_h | Hinata_et_al_2003 | H000653_01 | Info | Gamma-aminobutyric acid (GABA) B receptor, 1 | H000653_01 | AJ225028 | 167017 | GABBR1 | 0.9073787 | 1.014 | |
| 826 | NFKB_INDUCED_h | Hinata_et_al_2003 | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 827 | NFKB_INDUCED_h | Hinata_et_al_2003 | H014820_01 | Info | Mitogen-activated protein kinase 9 | H014820_01 | NM_002752 | 246857 | MAPK9 | MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.9883614 | 0.998 |
| 828 | DNA_DAMAGE_SIGNALLING_h | GO | H001935_01 | Info | Glyceraldehyde-3-phosphate dehydrogenase | H001935_01 | U34995 | 169476 | GAPD | 0.0001082 | 1.485 | |
| 829 | DNA_DAMAGE_SIGNALLING_h | GO | H002964_01 | Info | B-cell CLL/lymphoma 6 (zinc finger protein 51) | H002964_01 | U00115 | 155024 | BCL6 | misc, transcription | 0.0026913 | 1.659 |
| 830 | DNA_DAMAGE_SIGNALLING_h | GO | H002387_01 | Info | MutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1) | H002387_01 | NM_000251 | 78934 | MSH2 | DNA_damage, tsonc | 0.004273 | 0.694 |
| 831 | DNA_DAMAGE_SIGNALLING_h | GO | H001948_01 | Info | Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pig | H001948_01 | X69978 | 48576 | ERCC5 | DNA_damage, DNA_replication, immunology | 0.0043898 | 0.685 |
| 832 | DNA_DAMAGE_SIGNALLING_h | GO | H000599_01 | Info | Protein phosphatase 1D magnesium-dependent, delta isoform | H000599_01 | U78305 | 100980 | PPM1D | 0.0049252 | 1.53 | |
| 833 | DNA_DAMAGE_SIGNALLING_h | GO | H000208_01 | Info | Breast cancer 1, early onset | H000208_01 | NM_007295 | 194143 | BRCA1 | ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc | 0.009032 | 0.746 |
| 834 | DNA_DAMAGE_SIGNALLING_h | GO | H006842_01 | Info | Growth arrest and DNA-damage-inducible, beta | H006842_01 | AF078077 | 110571 | GADD45B | 0.0097838 | 1.244 | |
| 835 | DNA_DAMAGE_SIGNALLING_h | GO | H002092_01 | Info | Ataxia telangiectasia and Rad3 related | H002092_01 | U49844 | 77613 | ATR | Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology | 0.0105491 | 0.753 |
| 836 | DNA_DAMAGE_SIGNALLING_h | GO | H002799_01 | Info | Postmeiotic segregation increased (S. cerevisiae) 2 | H002799_01 | U14658 | 177548 | PMS2 | DNA_damage, immunology | 0.01291 | 0.772 |
| 837 | DNA_DAMAGE_SIGNALLING_h | GO | H002304_01 | Info | Cell division cycle 25B | H002304_01 | S78187 | 153752 | CDC25B | 0.0167858 | 0.8 | |
| 838 | DNA_DAMAGE_SIGNALLING_h | GO | H006026_01 | Info | Hypothetical protein | H006026_01 | AL137745 | 278408 | DKFZp434J0310 | Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.0211038 | 1.291 |
| 839 | DNA_DAMAGE_SIGNALLING_h | GO | H001906_01 | Info | CDC20 (cell division cycle 20, S. cerevisiae, homolog) | H001906_01 | U05340 | 82906 | CDC20 | 0.0270662 | 0.753 | |
| 840 | DNA_DAMAGE_SIGNALLING_h | GO | H002789_01 | Info | Tumor protein p53 (Li-Fraumeni syndrome) | H002789_01 | NM_000546 | 1846 | TP53 | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc | 0.0273242 | 1.207 |
| 841 | DNA_DAMAGE_SIGNALLING_h | GO | H004571_01 | Info | Meiotic recombination (S. cerevisiae) 11 homolog A | H004571_01 | U37359 | 20555 | MRE11A | ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.0280596 | 0.822 |
| 842 | DNA_DAMAGE_SIGNALLING_h | GO | H000328_01 | Info | Forkhead box O3A | H000328_01 | AF032886 | 14845 | FOXO3A | AKT Signaling Pathway, PTEN dependent cell cycle arrest and apoptosis, Role of nicotinic acetylcholine receptors in the regulation of apoptosis, The IGF-1 Receptor and Longevity | 0.0286928 | 0.767 |
| 843 | DNA_DAMAGE_SIGNALLING_h | GO | H002599_01 | Info | Proliferating cell nuclear antigen | H002599_01 | M15796 | 78996 | PCNA | p53 Signaling Pathway, cell_cycle, gene_regulation, transcription | 0.0303031 | 0.732 |
| 844 | DNA_DAMAGE_SIGNALLING_h | GO | H003759_01 | Info | Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | H003759_01 | U40343 | 29656 | CDKN2D | Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation | 0.0311312 | 1.253 |
| 845 | DNA_DAMAGE_SIGNALLING_h | GO | H002149_01 | Info | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | H002149_01 | U03106 | 179665 | CDKN1A | ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc | 0.0349766 | 1.236 |
| 846 | DNA_DAMAGE_SIGNALLING_h | GO | H002396_01 | Info | Ligase IV, DNA, ATP-dependent | H002396_01 | X83441 | 166091 | LIG4 | DNA_adducts, DNA_damage | 0.0568237 | 0.768 |
| 847 | DNA_DAMAGE_SIGNALLING_h | GO | H003113_01 | Info | Alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog) | H003113_01 | U72936 | 96264 | ATRX | DNA_replication, immunology, misc | 0.0585052 | 1.259 |
| 848 | DNA_DAMAGE_SIGNALLING_h | GO | H003091_01 | Info | X-ray repair complementing defective repair in Chinese hamster cells 4 | H003091_01 | U40622 | 150930 | XRCC4 | DNA_damage, DNA_replication | 0.0912208 | 0.871 |
| 849 | DNA_DAMAGE_SIGNALLING_h | GO | H000398_01 | Info | Protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 | H000398_01 | U49070 | 161362 | PIN1 | How Progesterone Initiates the Oocyte Maturation | 0.1163659 | 1.163 |
| 850 | DNA_DAMAGE_SIGNALLING_h | GO | H003271_01 | Info | N-methylpurine-DNA glycosylase | H003271_01 | M74905 | 79396 | MPG | DNA_damage | 0.1165252 | 0.866 |
| 851 | DNA_DAMAGE_SIGNALLING_h | GO | H002760_01 | Info | RAD51 (S. cerevisiae) homolog (E coli RecA homolog) | H002760_01 | D14134 | 23044 | RAD51 | ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication | 0.1212274 | 1.154 |
| 852 | DNA_DAMAGE_SIGNALLING_h | GO | H014546_01 | Info | Peptidylprolyl isomerase A (cyclophilin A) | H014546_01 | NM_021130 | 182937 | PPIA | IL-2 Receptor Beta Chain in T cell Activation | 0.129858 | 1.176 |
| 853 | DNA_DAMAGE_SIGNALLING_h | GO | H002699_01 | Info | Telomerase reverse transcriptase | H002699_01 | AF015950 | 115256 | TERT | Role of nicotinic acetylcholine receptors in the regulation of apoptosis, Telomeres, Telomerase, Cellular Aging, and Immortality, DNA_adducts, DNA_damage | 0.1330289 | 0.815 |
| 854 | DNA_DAMAGE_SIGNALLING_h | GO | H002171_01 | Info | Purine-rich element binding protein A | H002171_01 | M96684 | 29117 | PURA | 0.1338155 | 1.135 | |
| 855 | DNA_DAMAGE_SIGNALLING_h | GO | H002443_01 | Info | Baculoviral IAP repeat-containing 3 | H002443_01 | NM_001165 | 127799 | BIRC3 | Caspase Cascade in Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Role of Mitochondria in Apoptotic Signaling, SODD/TNFR1 Signaling Pathway | 0.1402862 | 0.84 |
| 856 | DNA_DAMAGE_SIGNALLING_h | GO | H014140_01 | Info | Leucine rich repeat and death domain containing protein | H014140_01 | NM_018494 | 123136 | LRDD | 0.1769387 | 0.848 | |
| 857 | DNA_DAMAGE_SIGNALLING_h | GO | H003048_01 | Info | Cell division cycle 25C | H003048_01 | M34065 | 656 | CDC25C | How Progesterone Initiates the Oocyte Maturation, Regulation of cell cycle progression by Plk3, cell_cycle, cell_signaling | 0.1856754 | 1.116 |
| 858 | DNA_DAMAGE_SIGNALLING_h | GO | H002206_01 | Info | Protease, cysteine, 1 (legumain) | H002206_01 | D55696 | 18069 | PRSC1 | 0.1971064 | 0.873 | |
| 859 | DNA_DAMAGE_SIGNALLING_h | GO | H003242_01 | Info | Excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pig | H003242_01 | M31899 | 77929 | ERCC3 | CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, DNA_damage, DNA_replication, immunology | 0.2157492 | 0.873 |
| 860 | DNA_DAMAGE_SIGNALLING_h | GO | H002298_01 | Info | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break | H002298_01 | M30938 | 84981 | XRCC5 | Telomeres, Telomerase, Cellular Aging, and Immortality, DNA_damage, DNA_replication | 0.2435454 | 1.101 |
| 861 | DNA_DAMAGE_SIGNALLING_h | GO | H003605_01 | Info | BCL2-associated X protein | H003605_01 | L22474 | 159428 | BAX | Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology | 0.253339 | 0.907 |
| 862 | DNA_DAMAGE_SIGNALLING_h | GO | H002577_01 | Info | MutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2) | H002577_01 | U07418 | 57301 | MLH1 | DNA_damage, DNA_replication, tsonc | 0.2947975 | 0.894 |
| 863 | DNA_DAMAGE_SIGNALLING_h | GO | H002771_01 | Info | APEX nuclease (multifunctional DNA repair enzyme) | H002771_01 | S43127 | 73722 | APEX | Granzyme A mediated Apoptosis Pathway | 0.3286377 | 0.907 |
| 864 | DNA_DAMAGE_SIGNALLING_h | GO | H007300_01 | Info | P53-inducible ribonucleotide reductase small subunit 2 homolog | H007300_01 | AB036063 | 94262 | p53R2 | 0.359173 | 1.087 | |
| 865 | DNA_DAMAGE_SIGNALLING_h | GO | H011910_01 | Info | Growth arrest and DNA-damage-inducible, beta | H011910_01 | AL050044 | 110571 | GADD45B | 0.3649069 | 1.104 | |
| 866 | DNA_DAMAGE_SIGNALLING_h | GO | H003192_01 | Info | CDC6 (cell division cycle 6, S. cerevisiae) homolog | H003192_01 | U77949 | 69563 | CDC6 | CDK Regulation of DNA Replication | 0.3771474 | 1.068 |
| 867 | DNA_DAMAGE_SIGNALLING_h | GO | H003351_01 | Info | Protein kinase, DNA-activated, catalytic polypeptide | H003351_01 | U47077 | 155637 | PRKDC | Cell Cycle: G2/M Checkpoint, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, TNFR1 Signaling Pathway, Phosphatidylinositol signaling system, DNA_damage, immunology | 0.3847336 | 0.919 |
| 868 | DNA_DAMAGE_SIGNALLING_h | GO | H010490_01 | Info | Three prime repair exonuclease 1 | H010490_01 | AJ243797 | 23595 | TREX1 | Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.3918377 | 1.111 |
| 869 | DNA_DAMAGE_SIGNALLING_h | GO | H002782_01 | Info | Wee1+ (S. pombe) homolog | H002782_01 | X62048 | 75188 | WEE1 | cdc25 and chk1 Regulatory Pathway in response to DNA damage, Cell Cycle: G2/M Checkpoint, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, immunology | 0.4033875 | 1.142 |
| 870 | DNA_DAMAGE_SIGNALLING_h | GO | H005930_01 | Info | P53 regulated PA26 nuclear protein | H005930_01 | AF033122 | 14125 | PA26 | 0.4606086 | 0.938 | |
| 871 | DNA_DAMAGE_SIGNALLING_h | GO | H003644_01 | Info | Tumor necrosis factor receptor superfamily, member 6 | H003644_01 | X63717 | 82359 | TNFRSF6 | apoptosis, immunology | 0.4621499 | 0.927 |
| 872 | DNA_DAMAGE_SIGNALLING_h | GO | H006805_01 | Info | Small fragment nuclease | H006805_01 | AL110239 | 7527 | DKFZP566E144 | 0.5304326 | 1.066 | |
| 873 | DNA_DAMAGE_SIGNALLING_h | GO | H001952_01 | Info | Ribosomal protein L13a | H001952_01 | X56932 | 119122 | RPL13A | 0.565051 | 1.059 | |
| 874 | DNA_DAMAGE_SIGNALLING_h | GO | H002242_01 | Info | RAD23 (S. cerevisiae) homolog A | H002242_01 | D21235 | 180455 | RAD23A | DNA_damage | 0.6207626 | 1.046 |
| 875 | DNA_DAMAGE_SIGNALLING_h | GO | H003538_01 | Info | Actin, beta | H003538_01 | NM_001101 | 288061 | ACTB | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes | 0.6253266 | 0.956 |
| 876 | DNA_DAMAGE_SIGNALLING_h | GO | H003045_01 | Info | Tumor necrosis factor receptor superfamily, member 10b | H003045_01 | AF016266 | 51233 | TNFRSF10B | 0.6371361 | 1.047 | |
| 877 | DNA_DAMAGE_SIGNALLING_h | GO | H002401_01 | Info | X-ray repair complementing defective repair in Chinese hamster cells 2 | H002401_01 | AF035587 | 129727 | XRCC2 | DNA_damage, DNA_replication, immunology | 0.638867 | 0.965 |
| 878 | DNA_DAMAGE_SIGNALLING_h | GO | H002986_01 | Info | RAD23 (S. cerevisiae) homolog B | H002986_01 | D21090 | 178658 | RAD23B | DNA_damage | 0.6468245 | 1.038 |
| 879 | DNA_DAMAGE_SIGNALLING_h | GO | H002063_01 | Info | Damage-specific DNA binding protein 2 (48kD) | H002063_01 | U18300 | 77602 | DDB2 | DNA_damage | 0.6666997 | 0.96 |
| 880 | DNA_DAMAGE_SIGNALLING_h | GO | H002571_01 | Info | Meiotic recombination (S. cerevisiae) 11 homolog B | H002571_01 | AF022778 | 202379 | MRE11B | ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.7288114 | 0.971 |
| 881 | DNA_DAMAGE_SIGNALLING_h | GO | H002821_01 | Info | Damage-specific DNA binding protein 1 (127kD) | H002821_01 | U32986 | 108327 | DDB1 | Perou’s – Intrinsic – Breast-Cancer-Genes, DNA_damage | 0.7405572 | 0.975 |
| 882 | DNA_DAMAGE_SIGNALLING_h | GO | H010946_01 | Info | Artemin | H010946_01 | AF109401 | 194689 | ARTN | 0.7609159 | 1.05 | |
| 883 | DNA_DAMAGE_SIGNALLING_h | GO | H003803_01 | Info | Baculoviral IAP repeat-containing 2 | H003803_01 | U37547 | 289107 | BIRC2 | Caspase Cascade in Apoptosis, Role of Mitochondria in Apoptotic Signaling | 0.7664906 | 1.03 |
| 884 | DNA_DAMAGE_SIGNALLING_h | GO | H000475_01 | Info | Apoptotic protease activating factor | H000475_01 | NM_013229 | 77579 | APAF1 | Apoptotic Signaling in Response to DNA Damage, Caspase Cascade in Apoptosis, D4-GDI Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , p53 Signaling Pathway, Role of Mitochondria in Apoptotic Signaling, Stress Induction of HSP Regulation, Trefoil Factors Initiate Mucosal Healing, apoptosis, immunology | 0.7764943 | 0.97 |
| 885 | DNA_DAMAGE_SIGNALLING_h | GO | H006841_01 | Info | Homo sapiens mRNA; cDNA DKFZp564P073 (from clone DKFZp564P073) | H006841_01 | AL049301 | 278577 | Apoptotic Signaling in Response to DNA Damage, Ceramide Signaling Pathway, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Regulation of BAD phosphorylation, Role of Mitochondria in Apoptotic Signaling, apoptosis, development, immunology | 0.7810094 | 0.98 | |
| 886 | DNA_DAMAGE_SIGNALLING_h | GO | H003772_01 | Info | Xeroderma pigmentosum, complementation group C | H003772_01 | D21089 | 320 | XPC | DNA_damage, immunology | 0.7950726 | 0.977 |
| 887 | DNA_DAMAGE_SIGNALLING_h | GO | H003766_01 | Info | Mouse double minute 2, human homolog of; p53-binding protein | H003766_01 | M92424 | 170027 | MDM2 | ATM Signaling Pathway, Cell Cycle: G2/M Checkpoint, CTCF: First Multivalent Nuclear Factor, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, p53 Signaling Pathway, Sumoylation by RanBP2 Regulates Transcriptional Repression, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, gene_regulation, transcription, tsonc | 0.8018001 | 0.978 |
| 888 | DNA_DAMAGE_SIGNALLING_h | GO | H003015_01 | Info | Excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes over | H003015_01 | M13194 | 59544 | ERCC1 | DNA_damage, DNA_replication, immunology | 0.8177868 | 1.024 |
| 889 | DNA_DAMAGE_SIGNALLING_h | GO | H001939_01 | Info | BTG family, member 2 | H001939_01 | U72649 | 75462 | BTG2 | BTG family proteins and cell cycle regulation | 0.8452859 | 0.981 |
| 890 | DNA_DAMAGE_SIGNALLING_h | GO | H009125_01 | Info | Bcl-2 binding component 3 | H009125_01 | U82987 | 87246 | BBC3 | 0.8477416 | 0.982 | |
| 891 | DNA_DAMAGE_SIGNALLING_h | GO | H002373_01 | Info | MutS (E. coli) homolog 3 | H002373_01 | U61981 | 42674 | MSH3 | DNA_damage, immunology | 0.8910817 | 0.986 |
| 892 | DNA_DAMAGE_SIGNALLING_h | GO | H000083_01 | Info | H2A histone family, member Z | H000083_01 | M37583 | 119192 | H2AFZ | 0.8912337 | 0.987 | |
| 893 | DNA_DAMAGE_SIGNALLING_h | GO | H000077_01 | Info | RAD1 (S. pombe) homolog | H000077_01 | AF030933 | 7179 | RAD1 | Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication | 0.927706 | 0.993 |
| 894 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002088_01 | Info | Prostaglandin E receptor 4 (subtype EP4) | H002088_01 | L25124 | 199248 | PTGER4 | Eicosanoid Metabolism | 0.0029063 | 0.734 |
| 895 | GPCRs_Class_A_Rhodopsin-like_h | GO | H004080_01 | Info | Histamine receptor H3 | H004080_01 | NM_007232 | 251399 | HRH3 | 0.0035969 | 0.66 | |
| 896 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003668_01 | Info | Histamine receptor H1 | H003668_01 | Z34897 | 1570 | HRH1 | 0.0076811 | 0.709 | |
| 897 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002813_01 | Info | 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled) | H002813_01 | U68488 | 73739 | HTR7 | immunology | 0.0089719 | 1.292 |
| 898 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002667_01 | Info | Prostaglandin E receptor 1 (subtype EP1), 42kD | H002667_01 | L22647 | 159360 | PTGER1 | Eicosanoid Metabolism, Phospholipase C-epsilon pathway | 0.0102067 | 1.228 |
| 899 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003590_01 | Info | Retinal G protein coupled receptor | H003590_01 | U14910 | 1544 | RGR | 0.0153777 | 1.301 | |
| 900 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002494_01 | Info | Adrenergic, alpha-1B-, receptor | H002494_01 | U03865 | 123055 | ADRA1B | Phospholipase C d1 in phospholipid associated cell signaling | 0.0200341 | 1.572 |
| 901 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002167_01 | Info | Chemokine binding protein 2 | H002167_01 | U94888 | 117572 | CCBP2 | 0.0225142 | 0.731 | |
| 902 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002027_01 | Info | Prostaglandin I2 (prostacyclin) receptor (IP) | H002027_01 | D25418 | 393 | PTGIR | Eicosanoid Metabolism, immunology | 0.0236242 | 0.789 |
| 903 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003343_01 | Info | Galanin receptor 1 | H003343_01 | NM_001480 | 272191 | GALR1 | 0.0260438 | 0.759 | |
| 904 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002347_01 | Info | Leukotriene b4 receptor (chemokine receptor-like 1) | H002347_01 | D89078 | 28408 | LTB4R | immunology | 0.0284508 | 1.35 |
| 905 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003130_01 | Info | Interleukin 8 receptor, beta | H003130_01 | L19593 | 846 | IL8RB | immunology | 0.0345675 | 1.307 |
| 906 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002464_01 | Info | G protein-coupled receptor 2 | H002464_01 | AF215981 | 278446 | GPR2 | immunology | 0.0493902 | 0.772 |
| 907 | GPCRs_Class_A_Rhodopsin-like_h | GO | H006487_01 | Info | Neuropeptide Y receptor Y6 (pseudogene) | H006487_01 | D86519 | 73086 | NPY6R | 0.0535714 | 1.212 | |
| 908 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003428_01 | Info | 5-hydroxytryptamine (serotonin) receptor 2A | H003428_01 | X57830 | 298623 | HTR2A | immunology | 0.0558704 | 1.169 |
| 909 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002592_01 | Info | Opioid receptor, mu 1 | H002592_01 | L25119 | 2353 | OPRM1 | behavior, immunology | 0.0609704 | 0.812 |
| 910 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003745_01 | Info | Neuropeptide Y receptor Y1 | H003745_01 | NM_000909 | 169266 | NPY1R | Perou’s – Intrinsic – Breast-Cancer-Genes, immunology | 0.0754043 | 1.285 |
| 911 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002332_01 | Info | Bradykinin receptor B2 | H002332_01 | NM_000623 | 250882 | BDKRB2 | Actions of Nitric Oxide in the Heart, angiogenesis, immunology | 0.0806551 | 0.852 |
| 912 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003670_01 | Info | Adrenergic, beta-1-, receptor | H003670_01 | J03019 | 99913 | ADRB1 | behavior, immunology | 0.0878218 | 1.205 |
| 913 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002366_01 | Info | Chemokine (C-C motif) receptor 9 | H002366_01 | NM_006641 | 225946 | CCR9 | 0.0908646 | 1.196 | |
| 914 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002585_01 | Info | G protein-coupled receptor 17 | H002585_01 | Z94155 | 46453 | GPR17 | 0.1077387 | 1.234 | |
| 915 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002758_01 | Info | Chemokine-like receptor 1 | H002758_01 | U79526 | 159553 | CMKLR1 | immunology | 0.1103372 | 1.187 |
| 916 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003899_01 | Info | Chemokine (C-C motif) receptor 1 | H003899_01 | D10925 | 301921 | CCR1 | Selective expression of chemokine receptors during T-cell polarization, immunology | 0.1258208 | 1.15 |
| 917 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002321_01 | Info | G protein-coupled receptor 30 | H002321_01 | AF015257 | 113207 | GPR30 | immunology | 0.1344665 | 1.164 |
| 918 | GPCRs_Class_A_Rhodopsin-like_h | GO | H015702_01 | Info | G protein-coupled receptor 44 | H015702_01 | NM_004778 | 299567 | GPR44 | 0.1450231 | 1.171 | |
| 919 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002567_01 | Info | Thyroid stimulating hormone receptor | H002567_01 | M31774 | 123078 | TSHR | immunology | 0.1458901 | 0.876 |
| 920 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002097_01 | Info | Dopamine receptor D2 | H002097_01 | X51362 | 73893 | DRD2 | behavior, immunology | 0.1531006 | 0.865 |
| 921 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002110_01 | Info | Coagulation factor II (thrombin) receptor | H002110_01 | NM_001992 | 128087 | F2R | Perou’s – Intrinsic – Breast-Cancer-Genes, Acute Myocardial Infarction, Extrinsic Prothrombin Activation Pathway, Fibrinolysis Pathway, Intrinsic Prothrombin Activation Pathway, immunology | 0.1560498 | 0.883 |
| 922 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002476_01 | Info | Chemokine (C-C motif) receptor 5 | H002476_01 | NM_000579 | 54443 | CCR5 | HIV Induced T Cell Apoptosis, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, NO2-dependent IL 12 Pathway in NK cells, Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Selective expression of chemokine receptors during T-cell polarization, immunology | 0.1574808 | 0.842 |
| 923 | GPCRs_Class_A_Rhodopsin-like_h | GO | H015524_01 | Info | AD026 protein | H015524_01 | NM_020683 | 28847 | AD026 | 0.1577677 | 1.184 | |
| 924 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002454_01 | Info | Follicle stimulating hormone receptor | H002454_01 | M65085 | 1428 | FSHR | Regulation of Spermatogenesis by CREM | 0.1580303 | 1.111 |
| 925 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002487_01 | Info | Complement component 5 receptor 1 (C5a ligand) | H002487_01 | M62505 | 2161 | C5R1 | immunology | 0.1622511 | 1.213 |
| 926 | GPCRs_Class_A_Rhodopsin-like_h | GO | H000667_01 | Info | Purinergic receptor (family A group 5) | H000667_01 | AF000546 | 189999 | P2Y5 | 0.1930389 | 0.884 | |
| 927 | GPCRs_Class_A_Rhodopsin-like_h | GO | H009013_01 | Info | Dopamine receptor D2 | H009013_01 | AF176812 | 73893 | DRD2 | behavior, immunology | 0.2238033 | 1.119 |
| 928 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003535_01 | Info | Galanin receptor 3 | H003535_01 | AF073799 | 158353 | GALR3 | 0.227577 | 1.12 | |
| 929 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003381_01 | Info | Melatonin receptor 1A | H003381_01 | U14108 | 248147 | MTNR1A | 0.3138134 | 1.113 | |
| 930 | GPCRs_Class_A_Rhodopsin-like_h | GO | H015755_01 | Info | Chemokine (C-C motif) receptor 1 | H015755_01 | NM_001295 | 301921 | CCR1 | Selective expression of chemokine receptors during T-cell polarization, immunology | 0.3366567 | 1.129 |
| 931 | GPCRs_Class_A_Rhodopsin-like_h | GO | H006918_01 | Info | Neuropeptide G protein-coupled receptor; neuropeptide FF 2 | H006918_01 | NM_004885 | 99231 | NPGPR | 0.4203767 | 0.905 | |
| 932 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002976_01 | Info | G protein-coupled receptor 9 | H002976_01 | X95876 | 198252 | GPR9 | IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, mCalpain and friends in Cell motility, NO2-dependent IL 12 Pathway in NK cells, Selective expression of chemokine receptors during T-cell polarization | 0.4390046 | 0.918 |
| 933 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002698_01 | Info | Adrenergic, beta-3-, receptor | H002698_01 | NM_000025 | 2549 | ADRB3 | behavior, immunology | 0.4399337 | 0.93 |
| 934 | GPCRs_Class_A_Rhodopsin-like_h | GO | H010325_01 | Info | Chemokine (C-C motif) receptor-like 2 | H010325_01 | AF015525 | 302043 | CCRL2 | 0.4610352 | 0.915 | |
| 935 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002378_01 | Info | Adrenergic, alpha-2C-, receptor | H002378_01 | J03853 | 123022 | ADRA2C | behavior, immunology | 0.4753686 | 1.073 |
| 936 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003577_01 | Info | Adrenergic, alpha-1A-, receptor | H003577_01 | D32202 | 52931 | ADRA1A | behavior | 0.5296756 | 1.062 |
| 937 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003424_01 | Info | Chemokine (C-C motif) receptor 3 | H003424_01 | U28694 | 158324 | CCR3 | CCR3 signaling in Eosinophils, IL 5 Signaling Pathway, Selective expression of chemokine receptors during T-cell polarization, The Role of Eosinophils in the Chemokine Network of Allergy, immunology | 0.5671442 | 1.138 |
| 938 | GPCRs_Class_A_Rhodopsin-like_h | GO | H007948_01 | Info | F-box and WD-40 domain protein 2 | H007948_01 | NM_012164 | 13755 | FBXW2 | 0.5814024 | 1.048 | |
| 939 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003584_01 | Info | Platelet-activating factor receptor | H003584_01 | D10202 | 46 | PTAFR | angiogenesis, immunology | 0.5977382 | 1.05 |
| 940 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003654_01 | Info | Coagulation factor II (thrombin) receptor-like 2 | H003654_01 | U92971 | 194351 | F2RL2 | immunology | 0.6746058 | 0.966 |
| 941 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002380_01 | Info | Chemokine (C-C motif) receptor 8 | H002380_01 | D49919 | 113222 | CCR8 | immunology | 0.6915296 | 1.035 |
| 942 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002317_01 | Info | Chemokine (C-X3-C) receptor 1 | H002317_01 | U20350 | 78913 | CX3CR1 | immunology | 0.7275779 | 1.038 |
| 943 | GPCRs_Class_A_Rhodopsin-like_h | GO | H016261_01 | Info | Putative G protein-coupled receptor 92 | H016261_01 | NM_020400 | 330563 | GPR92 | 0.7713793 | 0.962 | |
| 944 | GPCRs_Class_A_Rhodopsin-like_h | GO | H012371_01 | Info | Thyroid stimulating hormone receptor | H012371_01 | S82807 | 123078 | TSHR | immunology | 0.7783963 | 1.03 |
| 945 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003426_01 | Info | Prostaglandin D2 receptor (DP) | H003426_01 | U31099 | 158326 | PTGDR | 0.800069 | 0.971 | |
| 946 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003721_01 | Info | Dopamine receptor D4 | H003721_01 | L12398 | 99922 | DRD4 | behavior, immunology | 0.8251335 | 1.023 |
| 947 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002672_01 | Info | G protein-coupled receptor | H002672_01 | U67784 | 23016 | RDC1 | 0.8527585 | 0.967 | |
| 948 | GPCRs_Class_A_Rhodopsin-like_h | GO | H003854_01 | Info | Burkitt lymphoma receptor 1, GTP-binding protein | H003854_01 | X68149 | 113916 | BLR1 | 0.882872 | 0.982 | |
| 949 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002271_01 | Info | Neuropeptide Y receptor Y2 | H002271_01 | NM_000910 | 37125 | NPY2R | 0.9438408 | 0.993 | |
| 950 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002797_01 | Info | Adenosine A3 receptor | H002797_01 | NM_000677 | 258 | ADORA3 | 0.9481775 | 0.993 | |
| 951 | GPCRs_Class_A_Rhodopsin-like_h | GO | H002327_01 | Info | Adenosine A1 receptor | H002327_01 | L22214 | 77867 | ADORA1 | immunology | 0.9613941 | 1.005 |
| 952 | MAP00230_Purine_metabolism_h | GenMAPP | H000616_01 | Info | Nucleoside phosphorylase | H000616_01 | X00737 | 75514 | NP | Nicotinate and nicotinamide metabolism, Purine metabolism, Pyrimidine metabolism, gene_regulation, immunology, transcription | 0.0005739 | 0.632 |
| 953 | MAP00230_Purine_metabolism_h | GenMAPP | H001694_01 | Info | Phosphodiesterase 1A, calmodulin-dependent | H001694_01 | AL110263 | 41717 | PDE1A | Purine metabolism | 0.0008892 | 1.444 |
| 954 | MAP00230_Purine_metabolism_h | GenMAPP | H001384_01 | Info | Adenylate kinase 2 | H001384_01 | NM_013411 | 171811 | AK2 | Purine metabolism, cell_cycle, cell_signaling, signal_transduction | 0.0012864 | 0.699 |
| 955 | MAP00230_Purine_metabolism_h | GenMAPP | H002879_01 | Info | Polymerase (DNA directed), beta | H002879_01 | D29013 | 180107 | POLB | DNA polymerase, Purine metabolism, Pyrimidine metabolism, cell_cycle, DNA_damage, DNA_replication, immunology | 0.0052758 | 0.781 |
| 956 | MAP00230_Purine_metabolism_h | GenMAPP | H002671_01 | Info | Natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | H002671_01 | X15357 | 167382 | NPR1 | Purine metabolism | 0.0065717 | 0.774 |
| 957 | MAP00230_Purine_metabolism_h | GenMAPP | H000696_01 | Info | Natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) | H000696_01 | L13436 | 78518 | NPR2 | Purine metabolism | 0.0104594 | 0.718 |
| 958 | MAP00230_Purine_metabolism_h | GenMAPP | H001903_01 | Info | Polymerase (DNA directed), gamma | H001903_01 | X98093 | 80961 | POLG | DNA polymerase, Purine metabolism, Pyrimidine metabolism | 0.0148856 | 0.783 |
| 959 | MAP00230_Purine_metabolism_h | GenMAPP | H002908_01 | Info | Ribonucleotide reductase M1 polypeptide | H002908_01 | X59543 | 2934 | RRM1 | Purine metabolism, Pyrimidine metabolism, immunology, pharmacology | 0.0183576 | 0.781 |
| 960 | MAP00230_Purine_metabolism_h | GenMAPP | H000395_01 | Info | Guanine monophosphate synthetase | H000395_01 | U10860 | 5398 | GMPS | Glutamate metabolism, Purine metabolism | 0.0187326 | 0.757 |
| 961 | MAP00230_Purine_metabolism_h | GenMAPP | H007908_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide K (7.0kD) | H007908_01 | Z47727 | 150675 | POLR2K | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.0188042 | 0.756 |
| 962 | MAP00230_Purine_metabolism_h | GenMAPP | H002792_01 | Info | Xanthene dehydrogenase | H002792_01 | U39487 | 250 | XDH | Free Radical Induced Apoptosis, Purine metabolism, pharmacology | 0.0440945 | 0.829 |
| 963 | MAP00230_Purine_metabolism_h | GenMAPP | H003146_01 | Info | IMP (inosine monophosphate) dehydrogenase 1 | H003146_01 | J05272 | 850 | IMPDH1 | Purine metabolism, pharmacology | 0.0446339 | 1.284 |
| 964 | MAP00230_Purine_metabolism_h | GenMAPP | H007246_01 | Info | Phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal d | H007246_01 | S41458 | 2593 | PDE6B | Visual Signal Transduction, Purine metabolism | 0.0469463 | 1.226 |
| 965 | MAP00230_Purine_metabolism_h | GenMAPP | H007101_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide J (13.3kD) | H007101_01 | L37127 | 80475 | POLR2J | 0.0526802 | 1.218 | |
| 966 | MAP00230_Purine_metabolism_h | GenMAPP | H003792_01 | Info | Polymerase (DNA directed), alpha | H003792_01 | X06745 | 267289 | POLA | DNA polymerase, Purine metabolism, Pyrimidine metabolism, DNA_replication | 0.072381 | 0.83 |
| 967 | MAP00230_Purine_metabolism_h | GenMAPP | H002687_01 | Info | Ribonucleotide reductase M2 polypeptide | H002687_01 | X59618 | 75319 | RRM2 | Purine metabolism, Pyrimidine metabolism, pharmacology | 0.0826808 | 0.823 |
| 968 | MAP00230_Purine_metabolism_h | GenMAPP | H001372_01 | Info | Adenosine kinase | H001372_01 | NM_006721 | 94382 | ADK | Purine metabolism, cell_cycle, cell_signaling, immunology, signal_transduction | 0.0840666 | 0.848 |
| 969 | MAP00230_Purine_metabolism_h | GenMAPP | H002686_01 | Info | Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylamine | H002686_01 | X54199 | 82285 | GART | One carbon pool by folate, Purine metabolism, gene_regulation, transcription | 0.0902172 | 0.819 |
| 970 | MAP00230_Purine_metabolism_h | GenMAPP | H003507_01 | Info | Hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome) | H003507_01 | M31642 | 82314 | HPRT1 | Purine metabolism, immunology, pharmacology | 0.0959675 | 0.811 |
| 971 | MAP00230_Purine_metabolism_h | GenMAPP | H011566_01 | Info | Homo sapiens mutant DNA polymerase beta mRNA, partial CDS | H011566_01 | S69873 | 241525 | DNA polymerase, Purine metabolism, Pyrimidine metabolism, cell_cycle, DNA_damage, DNA_replication, immunology | 0.096998 | 0.865 | |
| 972 | MAP00230_Purine_metabolism_h | GenMAPP | H004544_01 | Info | Phosphodiesterase 6C, cGMP-specific, cone, alpha prime | H004544_01 | U31973 | 93173 | PDE6C | Purine metabolism | 0.141391 | 0.886 |
| 973 | MAP00230_Purine_metabolism_h | GenMAPP | H000576_01 | Info | Multifunctional polypeptide similar to SAICAR synthetase and AIR carboxylase | H000576_01 | X53793 | 117950 | ADE2H1 | Purine metabolism | 0.1457345 | 0.864 |
| 974 | MAP00230_Purine_metabolism_h | GenMAPP | H002295_01 | Info | Adenosine deaminase | H002295_01 | X02994 | 1217 | ADA | Purine metabolism, gene_regulation, immunology, transcription | 0.1882263 | 0.871 |
| 975 | MAP00230_Purine_metabolism_h | GenMAPP | H000394_01 | Info | Deoxycytidine kinase | H000394_01 | M60527 | 709 | DCK | Purine metabolism, Pyrimidine metabolism, gene_regulation, pharmacology, transcription | 0.1931198 | 0.887 |
| 976 | MAP00230_Purine_metabolism_h | GenMAPP | H010579_01 | Info | Guanine deaminase | H010579_01 | AB033084 | 239147 | GDA | Purine metabolism | 0.1976734 | 0.889 |
| 977 | MAP00230_Purine_metabolism_h | GenMAPP | H000074_01 | Info | Polymerase (DNA directed), delta 2, regulatory subunit (50kD) | H000074_01 | U21090 | 74598 | POLD2 | DNA polymerase, Purine metabolism, Pyrimidine metabolism | 0.203416 | 0.871 |
| 978 | MAP00230_Purine_metabolism_h | GenMAPP | H005568_01 | Info | Phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) | H005568_01 | U02882 | 172081 | PDE4D | Purine metabolism | 0.2410554 | 0.88 |
| 979 | MAP00230_Purine_metabolism_h | GenMAPP | H010908_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide E (25kD) | H010908_01 | D38251 | 24301 | POLR2E | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.2811044 | 1.09 |
| 980 | MAP00230_Purine_metabolism_h | GenMAPP | H000895_01 | Info | Guanylate cyclase 2C (heat stable enterotoxin receptor) | H000895_01 | M73489 | 1085 | GUCY2C | Purine metabolism | 0.2851741 | 1.091 |
| 981 | MAP00230_Purine_metabolism_h | GenMAPP | H002612_01 | Info | Adenylate cyclase 8 (brain) | H002612_01 | Z35309 | 2522 | ADCY8 | Purine metabolism | 0.2967064 | 0.881 |
| 982 | MAP00230_Purine_metabolism_h | GenMAPP | H000502_01 | Info | Phosphoribosyl pyrophosphate synthetase 1 | H000502_01 | D00860 | 56 | PRPS1 | Histidine metabolism, Pentose phosphate pathway, Purine metabolism, gene_regulation, transcription | 0.3045664 | 0.909 |
| 983 | MAP00230_Purine_metabolism_h | GenMAPP | H006451_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide H | H006451_01 | U37689 | 3128 | POLR2H | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.3071417 | 0.912 |
| 984 | MAP00230_Purine_metabolism_h | GenMAPP | H016370_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide I (14.5kD) | H016370_01 | NM_006233 | 47062 | POLR2I | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.3118426 | 1.12 |
| 985 | MAP00230_Purine_metabolism_h | GenMAPP | H003068_01 | Info | Pyruvate kinase, muscle | H003068_01 | M26252 | 198281 | PKM2 | Carbon fixation, Glycolysis / Gluconeogenesis, Purine metabolism, Pyruvate metabolism | 0.3246109 | 1.102 |
| 986 | MAP00230_Purine_metabolism_h | GenMAPP | H007868_01 | Info | Similar to DNA-directed RNA polymerase I (135 kDa) | H007868_01 | AK001678 | 86337 | FLJ10816 | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.3875312 | 1.072 |
| 987 | MAP00230_Purine_metabolism_h | GenMAPP | H005570_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide B (140kD) | H005570_01 | X63563 | 296014 | POLR2B | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.4005386 | 0.927 |
| 988 | MAP00230_Purine_metabolism_h | GenMAPP | H001616_01 | Info | Guanylate cyclase 1, soluble, beta 3 | H001616_01 | X66533 | 77890 | GUCY1B3 | Purine metabolism, signal_transduction | 0.4632953 | 0.93 |
| 989 | MAP00230_Purine_metabolism_h | GenMAPP | H008768_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide A (220kD) | H008768_01 | X63564 | 171880 | POLR2A | CARM1 and Regulation of the Estrogen Receptor, Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Repression of Pain Sensation by the Transcriptional Regulator DREAM, Telomeres, Telomerase, Cellular Aging, and Immortality, The information-processing pathway at the IFN-beta enhancer, Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.4709936 | 0.933 |
| 990 | MAP00230_Purine_metabolism_h | GenMAPP | H006464_01 | Info | Polymerase (RNA) II (DNA directed) polypeptide L (7.6kD) | H006464_01 | U37690 | 71618 | POLR2L | Purine metabolism, Pyrimidine metabolism, RNA polymerase | 0.5110537 | 0.933 |
| 991 | MAP00230_Purine_metabolism_h | GenMAPP | H001516_01 | Info | Guanosine monophosphate reductase | H001516_01 | M24470 | 1435 | GMPR | Purine metabolism | 0.5998588 | 0.932 |
| 992 | MAP00230_Purine_metabolism_h | GenMAPP | H001195_01 | Info | Adenylate cyclase 7 | H001195_01 | D25538 | 172199 | ADCY7 | Purine metabolism | 0.6383997 | 0.95 |
| 993 | MAP00230_Purine_metabolism_h | GenMAPP | H002833_01 | Info | Adenylate cyclase 6 | H002833_01 | AB007882 | 12373 | ADCY6 | Purine metabolism | 0.6504486 | 1.043 |
| 994 | MAP00230_Purine_metabolism_h | GenMAPP | H002572_01 | Info | Non-metastatic cells 2, protein (NM23B) expressed in | H002572_01 | M36981 | 275163 | NME2 | cell_cycle, cell_signaling, signal_transduction | 0.6557968 | 0.941 |
| 995 | MAP00230_Purine_metabolism_h | GenMAPP | H002590_01 | Info | Adenylate cyclase 2 (brain) | H002590_01 | AB028983 | 2352 | ADCY2 | Purine metabolism | 0.6751746 | 1.034 |
| 996 | MAP00230_Purine_metabolism_h | GenMAPP | H002195_01 | Info | Non-metastatic cells 1, protein (NM23A) expressed in | H002195_01 | X17620 | 118638 | NME1 | Endocytotic role of NDK, Phosphins and Dynamin, Granzyme A mediated Apoptosis Pathway, Purine metabolism, Pyrimidine metabolism, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc | 0.6910793 | 0.967 |
| 997 | MAP00230_Purine_metabolism_h | GenMAPP | H000388_01 | Info | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | H000388_01 | AL110183 | 73851 | ATP5J | ATP synthesis, Oxidative phosphorylation, misc | 0.7600099 | 0.953 |
| 998 | MAP00230_Purine_metabolism_h | GenMAPP | H007289_01 | Info | Insulin-like growth factor binding protein 7 | H007289_01 | S75725 | 119206 | IGFBP7 | 0.80895 | 1.034 | |
| 999 | MAP00230_Purine_metabolism_h | GenMAPP | H005402_01 | Info | Fragile histidine triad gene | H005402_01 | U46922 | 77252 | FHIT | Purine metabolism, tsonc | 0.9191308 | 1.011 |
| 1000 | MAP00230_Purine_metabolism_h | GenMAPP | H000621_01 | Info | Adenylosuccinate lyase | H000621_01 | AF067853 | 75527 | ADSL | Perou’s – Intrinsic – Breast-Cancer-Genes, Alanine and aspartate metabolism, Purine metabolism, misc | 0.9269914 | 0.99 |
| 1001 | MAP00230_Purine_metabolism_h | GenMAPP | H007645_01 | Info | Phosphodiesterase 4A, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E2) | H007645_01 | NM_006202 | 89901 | PDE4A | Purine metabolism, immunology | 0.9763196 | 0.997 |
| 1002 | raccycdPathway_h | BioCarta | H003112_01 | Info | Retinoblastoma 1 (including osteosarcoma) | H003112_01 | L41870 | 75770 | RB1 | BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Chaperones modulate interferon Signaling Pathway, Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, FAS signaling pathway ( CD95 ), HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Overview of telomerase RNA component gene hTerc Transcriptional Regulation, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Regulation of transcriptional activity by PML, Telomeres, Telomerase, Cellular Aging, and Immortality, TNFR1 Signaling Pathway, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, immunology, tsonc | 0.0008596 | 0.674 |
| 1003 | raccycdPathway_h | BioCarta | H002412_01 | Info | Cyclin-dependent kinase 2 | H002412_01 | M68520 | 19192 | CDK2 | CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of p27 Phosphorylation during Cell Cycle Progression, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, immunology, signal_transduction | 0.0040171 | 0.711 |
| 1004 | raccycdPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 1005 | raccycdPathway_h | BioCarta | H005436_01 | Info | Homo sapiens cDNA FLJ20653 fis, clone KAT01739 | H005436_01 | AK000660 | 180059 | Perou’s – Intrinsic – Breast-Cancer-Genes, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Influence of Ras and Rho proteins on G1 to S Transition, Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction | 0.0126769 | 0.793 | |
| 1006 | raccycdPathway_h | BioCarta | H002149_01 | Info | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | H002149_01 | U03106 | 179665 | CDKN1A | ATM Signaling Pathway, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Cyclins and Cell Cycle Regulation, Effects of calcineurin in Keratinocyte Differentiation, Erythropoietin mediated neuroprotection through NF-kB, Hypoxia and p53 in the Cardiovascular system, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, immunology, tsonc | 0.0349766 | 1.236 |
| 1007 | raccycdPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 1008 | raccycdPathway_h | BioCarta | H002287_01 | Info | P21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) | H002287_01 | U24152 | 62402 | PAK1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, FAS signaling pathway ( CD95 ), fMLP induced chemokine gene expression in HMC-1 cells, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Rac 1 cell motility signaling pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, TNFR1 Signaling Pathway | 0.1104284 | 0.815 |
| 1009 | raccycdPathway_h | BioCarta | H002323_01 | Info | Cyclin E1 | H002323_01 | M74093 | 9700 | CCNE1 | Perou’s – Intrinsic – Breast-Cancer-Genes, CDK Regulation of DNA Replication, Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, Regulation of p27 Phosphorylation during Cell Cycle Progression, cell_cycle | 0.1107382 | 0.884 |
| 1010 | raccycdPathway_h | BioCarta | H002501_01 | Info | Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | H002501_01 | D25274 | 173737 | RAC1 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, fMLP induced chemokine gene expression in HMC-1 cells, How does salmonella hijack a cell, Influence of Ras and Rho proteins on G1 to S Transition, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , Phosphoinositides and their downstream targets., Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Ras Signaling Pathway, Ras-Independent pathway in NK cell-mediated cytotoxicity, Role of MAL in Rho-Mediated Activation of SRF, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, T Cell Receptor Signaling Pathway, Transcription factor CREB and its extracellular signals, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, uCalpain and friends in Cell spread, Y branching of actin filaments | 0.1980127 | 1.118 |
| 1011 | raccycdPathway_h | BioCarta | H001999_01 | Info | Cyclin D1 (PRAD1: parathyroid adenomatosis 1) | H001999_01 | X59798 | 82932 | CCND1 | Perou’s – Intrinsic – Breast-Cancer-Genes, BTG family proteins and cell cycle regulation, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G1/S Check Point , Cyclins and Cell Cycle Regulation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, p53 Signaling Pathway, WNT Signaling Pathway, cell_cycle, tsonc | 0.3215316 | 0.898 |
| 1012 | raccycdPathway_h | BioCarta | H003162_01 | Info | Transcription factor Dp-1 | H003162_01 | L23959 | 279576 | TFDP1 | Cell Cycle: G1/S Check Point , Cyclin E Destruction Pathway, Cyclins and Cell Cycle Regulation, E2F1 Destruction Pathway, Influence of Ras and Rho proteins on G1 to S Transition, Regulation of p27 Phosphorylation during Cell Cycle Progression | 0.6646128 | 0.958 |
| 1013 | raccycdPathway_h | BioCarta | H003612_01 | Info | V-akt murine thymoma viral oncogene homolog 1 | H003612_01 | M63167 | 71816 | AKT1 | Actions of Nitric Oxide in the Heart, AKT Signaling Pathway, Apoptotic Signaling in Response to DNA Damage, B Cell Survival Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Corticosteroids and cardioprotection, Human Cytomegalovirus and Map Kinase Pathways, Hypoxia and p53 in the Cardiovascular system, IL 4 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, mTOR Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, NFAT and Hypertrophy of the heart (Transcription in the broken heart), Phosphoinositides and their downstream targets., Phospholipase C Signaling Pathway, Phospholipids as signaling intermediaries, PTEN dependent cell cycle arrest and apoptosis, Ras Signaling Pathway, Regulation … | 0.6741257 | 1.038 |
| 1014 | raccycdPathway_h | BioCarta | H002447_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | H002447_01 | M69043 | 81328 | NFKBIA | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … | 0.8245205 | 0.975 |
| 1015 | raccycdPathway_h | BioCarta | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 1016 | raccycdPathway_h | BioCarta | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 1017 | stressPathway_h | BioCarta | H003200_01 | Info | Mitogen-activated protein kinase kinase 3 | H003200_01 | D87116 | 180533 | MAP2K3 | fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, Signal transduction through IL1R, TNF/Stress Related Signaling, Toll-Like Receptor Pathway | 0.0009666 | 1.561 |
| 1018 | stressPathway_h | BioCarta | H002400_01 | Info | CASP2 and RIPK1 domain containing adaptor with death domain | H002400_01 | U84388 | 155566 | CRADD | HIV-I Nef: negative effector of Fas and TNF, TNF/Stress Related Signaling, TNFR1 Signaling Pathway | 0.0051676 | 0.703 |
| 1019 | stressPathway_h | BioCarta | H003232_01 | Info | Mitogen-activated protein kinase kinase kinase 14 | H003232_01 | Y10256 | 47007 | MAP3K14 | CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Keratinocyte Differentiation, MAP Kinase Signaling Pathway, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.005309 | 0.755 |
| 1020 | stressPathway_h | BioCarta | H002895_01 | Info | Mitogen-activated protein kinase 14 | H002895_01 | L35263 | 79107 | MAPK14 | BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), fMLP induced chemokine gene expression in HMC-1 cells, GATA3 participate in activating the Th2 cytokine genes expression, Human Cytomegalovirus and Map Kinase Pathways, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, Map Kinase Inactivation of SMRT Corepressor, MAP Kinase Signaling Pathway, NFAT and Hypertrophy of the heart (Transcription in the broken heart), NFkB activation by Nontypeable Hemophilus influenzae, Oxidative Stress Induced Gene Expression Via Nrf2, p38 MAPK Signaling Pathway , Pertussis toxin-insensitive CCR5 Signaling in Macrophage, Regulation of eIF4e and p70 S6 Kinase, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, SARS Coronavirus Protease, Signal transduction through IL1R, TACI and BCMA stimulation of B cell imm … | 0.0086925 | 1.429 |
| 1021 | stressPathway_h | BioCarta | H003611_01 | Info | Mitogen-activated protein kinase kinase 4 | H003611_01 | L36870 | 75217 | MAP2K4 | Perou’s – Intrinsic – Breast-Cancer-Genes, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Ceramide Signaling Pathway, EGF Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, Inhibition of Cellular Proliferation by Gleevec, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, p38 MAPK Signaling Pathway , PDGF Signaling Pathway, T Cell Receptor Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, Toll-Like Receptor Pathway, Phosphatidylinositol signaling system | 0.012502 | 0.753 |
| 1022 | stressPathway_h | BioCarta | H002503_01 | Info | TRAF family member-associated NFKB activator | H002503_01 | U59863 | 146847 | TANK | TNF/Stress Related Signaling, TNFR2 Signaling Pathway | 0.0790393 | 1.195 |
| 1023 | stressPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 1024 | stressPathway_h | BioCarta | H000042_01 | Info | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | H000042_01 | AF074382 | 43505 | IKBKG | CD40L Signaling Pathway, NF-kB Signaling Pathway, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway | 0.2784213 | 1.13 |
| 1025 | stressPathway_h | BioCarta | H002660_01 | Info | TNFRSF1A-associated via death domain | H002660_01 | L41690 | 89862 | TRADD | Acetylation and Deacetylation of RelA in The Nucleus, Ceramide Signaling Pathway, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , MAP Kinase Signaling Pathway, NF-kB Signaling Pathway, p38 MAPK Signaling Pathway , SODD/TNFR1 Signaling Pathway, TNF/Stress Related Signaling, TNFR1 Signaling Pathway | 0.3157474 | 1.092 |
| 1026 | stressPathway_h | BioCarta | H002136_01 | Info | Mitogen-activating protein kinase kinase kinase kinase 2 | H002136_01 | U07349 | 82979 | MAP4K2 | MAP Kinase Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, TNF/Stress Related Signaling, Phosphatidylinositol signaling system | 0.8239916 | 1.021 |
| 1027 | stressPathway_h | BioCarta | H002447_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | H002447_01 | M69043 | 81328 | NFKBIA | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Signal transduction through IL1R, T Cell Receptor Signaling Pathway, The 4-1BB-dependent immune … | 0.8245205 | 0.975 |
| 1028 | stressPathway_h | BioCarta | H002720_01 | Info | Caspase 2, apoptosis-related cysteine protease (neural precursor cell expressed, developmentally dow | H002720_01 | U13022 | 108131 | CASP2 | Caspase Cascade in Apoptosis, HIV-I Nef: negative effector of Fas and TNF, TNF/Stress Related Signaling, TNFR1 Signaling Pathway, apoptosis, immunology | 0.8522886 | 1.015 |
| 1029 | stressPathway_h | BioCarta | H001376_01 | Info | Homo sapiens mRNA; cDNA DKFZp566L084 (from clone DKFZp566L084) | H001376_01 | AL133012 | 306440 | Acetylation and Deacetylation of RelA in The Nucleus, AKT Signaling Pathway, CD40L Signaling Pathway, Double Stranded RNA Induced Gene Expression, HIV-I Nef: negative effector of Fas and TNF, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, Ras Signaling Pathway, Signal transduction through IL1R, TACI and BCMA stimulation of B cell immune responses., The 4-1BB-dependent immune response, TNF/Stress Related Signaling, TNFR2 Signaling Pathway, Toll-Like Receptor Pathway, cell_cycle, cell_signaling, signal_transduction | 0.8639394 | 0.98 | |
| 1030 | stressPathway_h | BioCarta | H003711_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | H003711_01 | M58603 | 83428 | NFKB1 | Acetylation and Deacetylation of RelA in The Nucleus, Activation of PKC through G protein coupled receptor, AKT Signaling Pathway, ATM Signaling Pathway, Bone Remodelling, Cadmium induces DNA synthesis and proliferation in macrophages, CD40L Signaling Pathway, Ceramide Signaling Pathway, Chaperones modulate interferon Signaling Pathway, Corticosteroids and cardioprotection, CXCR4 Signaling Pathway, Double Stranded RNA Induced Gene Expression, Erythropoietin mediated neuroprotection through NF-kB, fMLP induced chemokine gene expression in HMC-1 cells, Free Radical Induced Apoptosis, HIV-I Nef: negative effector of Fas and TNF, Human Cytomegalovirus and Map Kinase Pathways, Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages, Induction of apoptosis through DR3 and DR4/5 Death Receptors , Influence of Ras and Rho proteins on G1 to S Transition, Keratinocyte Differentiation, MAP Kinase Signaling Pathway, Neuropeptides VIP and PACAP inhibit the apoptosis of a … | 0.8665095 | 1.017 |
| 1031 | stressPathway_h | BioCarta | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 1032 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H010960_01 | Info | ATPase, H+ transporting, lysosomal (vacuolar proton pump) 9kD | H010960_01 | Y15286 | 24322 | ATP6H | ATP synthesis, Oxidative phosphorylation | 0.0040218 | 1.381 |
| 1033 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H006293_01 | Info | ATPase, H+ transporting, lysosomal (vacuolar proton pump) 21kD | H006293_01 | D89052 | 7476 | ATP6F | Perou’s – Intrinsic – Breast-Cancer-Genes, ATP synthesis, Oxidative phosphorylation | 0.0071282 | 1.372 |
| 1034 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H005994_01 | Info | ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta polypeptide, 56/58kD, isoform 2 | H005994_01 | L35249 | 1697 | ATP6B2 | ATP synthesis, Oxidative phosphorylation | 0.0127017 | 1.516 |
| 1035 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H000956_01 | Info | ATPase, H+/K+ exchanging, beta polypeptide | H000956_01 | NM_000705 | 813 | ATP4B | Oxidative phosphorylation, immunology | 0.0161188 | 0.699 |
| 1036 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H006153_01 | Info | ATPase, vacuolar, 14 kD | H006153_01 | D49400 | 78089 | ATP6S14 | ATP synthesis, Oxidative phosphorylation | 0.0256951 | 1.23 |
| 1037 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H001510_01 | Info | NADH dehydrogenase (ubiquinone) Fe-S protein 1 (75kD) (NADH-coenzyme Q reductase) | H001510_01 | X61100 | 8248 | NDUFS1 | Oxidative phosphorylation, Ubiquinone biosynthesis | 0.0288517 | 0.831 |
| 1038 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H002949_01 | Info | Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | H002949_01 | L21936 | 469 | SDHA | Perou’s – Intrinsic – Breast-Cancer-Genes, Citrate cycle (TCA cycle), Oxidative phosphorylation | 0.0908827 | 1.142 |
| 1039 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H008343_01 | Info | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | H008343_01 | NM_006886 | 177530 | ATP5E | ATP synthesis, Oxidative phosphorylation | 0.1448929 | 1.178 |
| 1040 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H001573_01 | Info | NADH dehydrogenase (ubiquinone) flavoprotein 2 (24kD) | H001573_01 | M22538 | 51299 | NDUFV2 | Oxidative phosphorylation, Ubiquinone biosynthesis | 0.1490894 | 1.169 |
| 1041 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H009190_01 | Info | ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD | H009190_01 | X76228 | 77805 | ATP6E | ATP synthesis, Oxidative phosphorylation | 0.1979177 | 0.85 |
| 1042 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H009093_01 | Info | Zinc finger protein 183 (RING finger, C3HC4 type) | H009093_01 | X98253 | 64794 | ZNF183 | 0.2244402 | 0.887 | |
| 1043 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H001563_01 | Info | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (13kD, B13) | H001563_01 | NM_005000 | 83916 | NDUFA5 | Oxidative phosphorylation, Ubiquinone biosynthesis | 0.2314122 | 1.096 |
| 1044 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H016294_01 | Info | Cytochrome c oxidase subunit VIIc | H016294_01 | NM_001867 | 3462 | COX7C | Oxidative phosphorylation, misc | 0.2776215 | 1.133 |
| 1045 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H004736_01 | Info | Cytochrome c oxidase subunit VIIb | H004736_01 | Z14244 | 75752 | COX7B | Oxidative phosphorylation | 0.3908231 | 1.097 |
| 1046 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H007379_01 | Info | Ubiquinol-cytochrome c reductase core protein I | H007379_01 | L16842 | 119251 | UQCRC1 | Electron Transport Reaction in Mitochondria, Oxidative phosphorylation | 0.39336 | 1.084 |
| 1047 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H007321_01 | Info | Cytochrome c oxidase subunit Va | H007321_01 | M22760 | 181028 | COX5A | Oxidative phosphorylation, misc | 0.5263245 | 0.936 |
| 1048 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H001069_01 | Info | ATPase, H+ transporting, lysosomal (vacuolar proton pump) non-catalytic accessory protein 1A (110/11 | H001069_01 | Z71460 | 267871 | ATP6N1A | ATP synthesis, Oxidative phosphorylation | 0.6964768 | 1.037 |
| 1049 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H009563_01 | Info | Ubiquinol-cytochrome c reductase binding protein | H009563_01 | M22348 | 131255 | UQCRB | Oxidative phosphorylation | 0.7540579 | 1.037 |
| 1050 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H010619_01 | Info | Ubiquinol-cytochrome c reductase core protein II | H010619_01 | J04973 | 173554 | UQCRC2 | Oxidative phosphorylation | 0.7842808 | 1.031 |
| 1051 | MAP00190_Oxidative_phosphorylation_h | GenMAPP | H001705_01 | Info | ATPase, Cu++ transporting, beta polypeptide (Wilson disease) | H001705_01 | U11700 | 84999 | ATP7B | immunology | 0.8244516 | 0.981 |
| 1052 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H000208_01 | Info | Breast cancer 1, early onset | H000208_01 | NM_007295 | 194143 | BRCA1 | ATM Signaling Pathway, BRCA1-dependent Ub-ligase activity, CARM1 and Regulation of the Estrogen Receptor, Cell Cycle: G2/M Checkpoint, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology, tsonc | 0.009032 | 0.746 |
| 1053 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H001983_01 | Info | Fanconi anemia, complementation group G | H001983_01 | AJ007669 | 8047 | FANCG | BRCA1-dependent Ub-ligase activity, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology | 0.0098981 | 0.692 |
| 1054 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H002092_01 | Info | Ataxia telangiectasia and Rad3 related | H002092_01 | U49844 | 77613 | ATR | Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Regulation of cell cycle progression by Plk3, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Phosphatidylinositol signaling system, DNA_replication, immunology | 0.0105491 | 0.753 |
| 1055 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H006026_01 | Info | Hypothetical protein | H006026_01 | AL137745 | 278408 | DKFZp434J0310 | Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.0211038 | 1.291 |
| 1056 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H002789_01 | Info | Tumor protein p53 (Li-Fraumeni syndrome) | H002789_01 | NM_000546 | 1846 | TP53 | Apoptotic Signaling in Response to DNA Damage, ATM Signaling Pathway, BTG family proteins and cell cycle regulation, Cell Cycle: G1/S Check Point , Cell Cycle: G2/M Checkpoint, Chaperones modulate interferon Signaling Pathway, CTCF: First Multivalent Nuclear Factor, Double Stranded RNA Induced Gene Expression, Estrogen-responsive protein Efp controls cell cycle and breast tumors growth, Hypoxia and p53 in the Cardiovascular system, Overview of telomerase protein component gene hTert Transcriptional Regulation , p53 Signaling Pathway, RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage, Regulation of cell cycle progression by Plk3, Regulation of transcriptional activity by PML, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, DNA_damage, gene_regulation, immunology, transcription, tsonc | 0.0273242 | 1.207 |
| 1057 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H004571_01 | Info | Meiotic recombination (S. cerevisiae) 11 homolog A | H004571_01 | U37359 | 20555 | MRE11A | ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.0280596 | 0.822 |
| 1058 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H002760_01 | Info | RAD51 (S. cerevisiae) homolog (E coli RecA homolog) | H002760_01 | D14134 | 23044 | RAD51 | ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication | 0.1212274 | 1.154 |
| 1059 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H010490_01 | Info | Three prime repair exonuclease 1 | H010490_01 | AJ243797 | 23595 | TREX1 | Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.3918377 | 1.111 |
| 1060 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H004597_01 | Info | Fanconi anemia, complementation group C | H004597_01 | X66893 | 37953 | FANCC | BRCA1-dependent Ub-ligase activity, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, immunology | 0.4823553 | 1.084 |
| 1061 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H014388_01 | Info | Homo sapiens Fanconi anemia complementation group D2 protein (FANCD2) mRNA, complete CDS, alternative | H014388_01 | AF340183 | 15607 | BRCA1-dependent Ub-ligase activity, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.5088959 | 0.937 | |
| 1062 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H002571_01 | Info | Meiotic recombination (S. cerevisiae) 11 homolog B | H002571_01 | AF022778 | 202379 | MRE11B | ATM Signaling Pathway, Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility | 0.7288114 | 0.971 |
| 1063 | atrbrcaPathway_h | BRCA1 and 2 block cell cycle progression in response to DNA damage and promote double-stranded break repair; mutations induce breast cancer susceptibility. | H000077_01 | Info | RAD1 (S. pombe) homolog | H000077_01 | AF030933 | 7179 | RAD1 | Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility, DNA_damage, DNA_replication | 0.927706 | 0.993 |
| 1064 | EMT_DOWN_h | Jechlinger_et_al_2003 | H002800_01 | Info | Connective tissue growth factor | H002800_01 | X78947 | 75511 | CTGF | immunology, misc | 0.0004011 | 0.555 |
| 1065 | EMT_DOWN_h | Jechlinger_et_al_2003 | H002964_01 | Info | B-cell CLL/lymphoma 6 (zinc finger protein 51) | H002964_01 | U00115 | 155024 | BCL6 | misc, transcription | 0.0026913 | 1.659 |
| 1066 | EMT_DOWN_h | Jechlinger_et_al_2003 | H003834_01 | Info | Integrin, beta 5 | H003834_01 | X53002 | 149846 | ITGB5 | cell_signaling, immunology, metastasis | 0.0034524 | 1.487 |
| 1067 | EMT_DOWN_h | Jechlinger_et_al_2003 | H003132_01 | Info | Nicotinamide nucleotide transhydrogenase | H003132_01 | U40490 | 18136 | NNT | Nicotinate and nicotinamide metabolism | 0.0190971 | 0.722 |
| 1068 | EMT_DOWN_h | Jechlinger_et_al_2003 | H011186_01 | Info | Growth factor receptor-bound protein 7 | H011186_01 | D43772 | 86859 | GRB7 | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.0262471 | 0.742 |
| 1069 | EMT_DOWN_h | Jechlinger_et_al_2003 | H009928_01 | Info | Kruppel-like factor 2 (lung) | H009928_01 | NM_016270 | 107740 | KLF2 | 0.1082236 | 1.312 | |
| 1070 | EMT_DOWN_h | Jechlinger_et_al_2003 | H009527_01 | Info | Vesicle-associated membrane protein 8 (endobrevin) | H009527_01 | AF053233 | 172684 | VAMP8 | 0.1745678 | 1.173 | |
| 1071 | EMT_DOWN_h | Jechlinger_et_al_2003 | H000372_01 | Info | Early growth response 2 (Krox-20 (Drosophila) homolog) | H000372_01 | NM_000399 | 1395 | EGR2 | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, immunology | 0.1772326 | 0.796 |
| 1072 | EMT_DOWN_h | Jechlinger_et_al_2003 | H002555_01 | Info | Junction plakoglobin | H002555_01 | Z68228 | 2340 | JUP | immunology | 0.1776342 | 0.877 |
| 1073 | EMT_DOWN_h | Jechlinger_et_al_2003 | H004003_01 | Info | FBJ murine osteosarcoma viral oncogene homolog B | H004003_01 | L49169 | 75678 | FOSB | FOSB gene expression and drug abuse, immunology, tsonc | 0.2326486 | 1.128 |
| 1074 | EMT_DOWN_h | Jechlinger_et_al_2003 | H008117_01 | Info | Stem cell factor {alternatively spliced} [human, preimplantation embryos, blastocysts, mRNA Partial, | H008117_01 | S80491 | 123028 | CDK Regulation of DNA Replication, Erythrocyte Differentiation Pathway, IL 17 Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Regulation of BAD phosphorylation | 0.2707834 | 1.106 | |
| 1075 | EMT_DOWN_h | Jechlinger_et_al_2003 | H008736_01 | Info | Human clone 23612 mRNA sequence | H008736_01 | U90902 | 82141 | cell_signaling, signal_transduction, tsonc | 0.3721668 | 1.128 | |
| 1076 | EMT_DOWN_h | Jechlinger_et_al_2003 | H002907_01 | Info | Retinoic acid receptor, alpha | H002907_01 | X06614 | 250505 | RARA | Degradation of the RAR and RXR by the proteasome, Map Kinase Inactivation of SMRT Corepressor, Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of transcriptional activity by PML, Transcription Regulation by Methyltransferase of CARM1, development | 0.4825926 | 1.084 |
| 1077 | EMT_DOWN_h | Jechlinger_et_al_2003 | H000698_01 | Info | Plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | H000698_01 | Z34974 | 198382 | PKP1 | 0.5763801 | 0.936 | |
| 1078 | EMT_DOWN_h | Jechlinger_et_al_2003 | H001214_01 | Info | Coagulation factor III (thromboplastin, tissue factor) | H001214_01 | J02931 | 62192 | F3 | Extrinsic Prothrombin Activation Pathway, angiogenesis, immunology, metastasis | 0.5811763 | 0.941 |
| 1079 | EMT_DOWN_h | Jechlinger_et_al_2003 | H003024_01 | Info | Cathepsin H | H003024_01 | X16832 | 288181 | CTSH | Perou’s – Intrinsic – Breast-Cancer-Genes | 0.5964026 | 1.048 |
| 1080 | EMT_DOWN_h | Jechlinger_et_al_2003 | H002859_01 | Info | Cadherin 1, type 1, E-cadherin (epithelial) | H002859_01 | Z13009 | 194657 | CDH1 | Perou’s – Intrinsic – Breast-Cancer-Genes, Downregulated of MTA-3 in ER-negative Breast Tumors, SUMOylation as a mechanism to modulate CtBP-dependent gene responses, TGF beta signaling pathway, tsonc | 0.6478575 | 0.95 |
| 1081 | EMT_DOWN_h | Jechlinger_et_al_2003 | H010580_01 | Info | S-adenosylmethionine decarboxylase 1 | H010580_01 | NM_001634 | 262476 | AMD1 | Arginine and proline metabolism | 0.783262 | 0.974 |
| 1082 | EMT_DOWN_h | Jechlinger_et_al_2003 | H003434_01 | Info | Dual specificity phosphatase 1 | H003434_01 | NM_004417 | 171695 | DUSP1 | CD40L Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, Regulation of MAP Kinase Pathways Through Dual Specificity Phosphatases, TNFR2 Signaling Pathway | 0.8183145 | 0.968 |
| 1083 | EMT_DOWN_h | Jechlinger_et_al_2003 | H003687_01 | Info | T-cell lymphoma invasion and metastasis 1 | H003687_01 | U16296 | 115176 | TIAM1 | cell_signaling, signal_transduction, tsonc | 0.8406417 | 1.019 |
| 1084 | EMT_DOWN_h | Jechlinger_et_al_2003 | H000822_01 | Info | Filamin A, alpha (actin-binding protein-280) | H000822_01 | X53416 | 195464 | FLNA | cell_signaling, metastasis | 0.9573941 | 1.004 |
| 1085 | ngfPathway_h | BioCarta | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 1086 | ngfPathway_h | BioCarta | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 1087 | ngfPathway_h | BioCarta | H014033_01 | Info | Dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | H014033_01 | NM_003863 | 108973 | DPM2 | 0.0983172 | 1.165 | |
| 1088 | ngfPathway_h | BioCarta | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 1089 | ngfPathway_h | BioCarta | H003158_01 | Info | Mitogen-activated protein kinase 8 | H003158_01 | L26318 | 190913 | MAPK8 | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, ATM Signaling Pathway, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Bone Remodelling, Ceramide Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, FAS signaling pathway ( CD95 ), Fc Epsilon Receptor I Signaling in Mast Cells, HIV-I Nef: negative effector of Fas and TNF, Hypoxia and p53 in the Cardiovascular system, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL12 and Stat4 Dependent Signaling Pathway in Th1 Development, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Nerve growth factor pathway (NGF), NFAT and Hypertrophy of the heart (Transcription in the broken heart), Oxidative Stress Induced Gene Expression Via Nrf2, PDGF Signaling Pathway, Pertussis toxin-insensitive CCR5 Sig … | 0.1287835 | 1.166 |
| 1090 | ngfPathway_h | BioCarta | H002724_01 | Info | Nerve growth factor receptor (TNFR superfamily, member 16) | H002724_01 | M14764 | 1827 | NGFR | Erk1/Erk2 Mapk Signaling pathway, Nerve growth factor pathway (NGF), Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway | 0.3282897 | 1.142 |
| 1091 | ngfPathway_h | BioCarta | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 1092 | ngfPathway_h | BioCarta | H002751_01 | Info | Nerve growth factor, beta polypeptide | H002751_01 | X52599 | 2561 | NGFB | BTG family proteins and cell cycle regulation, Erk1/Erk2 Mapk Signaling pathway, Nerve growth factor pathway (NGF), Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Trka Receptor Signaling Pathway, immunology, misc | 0.8279588 | 1.019 |
| 1093 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002420_01 | Info | Promyelocytic leukemia | H002420_01 | M79462 | 89633 | PML | Regulation of transcriptional activity by PML, gene_regulation, immunology, transcription | 0.0004143 | 0.71 |
| 1094 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003463_01 | Info | Spleen focus forming virus (SFFV) proviral integration oncogene spi1 | H003463_01 | X52056 | 157441 | SPI1 | tsonc | 0.0010958 | 1.855 |
| 1095 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002186_01 | Info | Serum response factor (c-fos serum response element-binding transcription factor) | H002186_01 | J03161 | 155321 | SRF | EGF Signaling Pathway, Growth Hormone Signaling Pathway, Hop Pathway in Cardiac Development, IGF-1 Signaling Pathway, IL 6 signaling pathway, Insulin Signaling Pathway, PDGF Signaling Pathway, Role of MAL in Rho-Mediated Activation of SRF, cell_cycle, cell_signaling, development, gene_regulation, transcription | 0.0017465 | 0.722 |
| 1096 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003672_01 | Info | FOS-like antigen-1 | H003672_01 | X16707 | 283565 | FOSL1 | Bone Remodelling, tsonc | 0.0019097 | 0.779 |
| 1097 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002406_01 | Info | Jun B proto-oncogene | H002406_01 | X51345 | 198951 | JUNB | GATA3 participate in activating the Th2 cytokine genes expression, tsonc | 0.0021761 | 1.408 |
| 1098 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002964_01 | Info | B-cell CLL/lymphoma 6 (zinc finger protein 51) | H002964_01 | U00115 | 155024 | BCL6 | misc, transcription | 0.0026913 | 1.659 |
| 1099 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003606_01 | Info | Retinoid X receptor, alpha | H003606_01 | U66306 | 20084 | RXRA | Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Control of Gene Expression by Vitamin D Receptor, Degradation of the RAR and RXR by the proteasome, FXR and LXR Regulation of Cholesterol Metabolism, Map Kinase Inactivation of SMRT Corepressor, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells, Role of PPAR-gamma Coactivators in Obesity and Thermogenesis, Transcription Regulation by Methyltransferase of CARM1, Visceral Fat Deposits and the Metabolic Syndrome, development, gene_regulation, transcription | 0.0142664 | 1.308 |
| 1100 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H000268_01 | Info | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | H000268_01 | U29175 | 78202 | SMARCA4 | Chromatin Remodeling by hSWI/SNF ATP-dependent Complexes, Control of Gene Expression by Vitamin D Receptor, development | 0.0190107 | 0.77 |
| 1101 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H000211_01 | Info | Glioma-associated oncogene homolog (zinc finger protein) | H000211_01 | X07384 | 2693 | GLI | development, gene_regulation, transcription, tsonc | 0.0229022 | 0.821 |
| 1102 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003009_01 | Info | V-myb avian myeloblastosis viral oncogene homolog-like 2 | H003009_01 | X13293 | 179718 | MYBL2 | tsonc | 0.0257612 | 0.656 |
| 1103 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H001315_01 | Info | Runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | H001315_01 | D43968 | 129914 | RUNX1 | 0.0288879 | 0.822 | |
| 1104 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H000343_01 | Info | Early growth response 3 | H000343_01 | X63741 | 74088 | EGR3 | Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, cell_signaling | 0.0317099 | 0.777 |
| 1105 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003156_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide | H003156_01 | M83221 | 858 | RELB | tsonc | 0.0527226 | 1.209 |
| 1106 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002934_01 | Info | Jun D proto-oncogene | H002934_01 | X56681 | 2780 | JUND | B Cell Survival Pathway, FOSB gene expression and drug abuse, gene_regulation, transcription, tsonc | 0.0585954 | 1.197 |
| 1107 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H006601_01 | Info | V-maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog | H006601_01 | AF055376 | 30250 | MAF | GATA3 participate in activating the Th2 cytokine genes expression, tsonc | 0.079493 | 0.812 |
| 1108 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H008525_01 | Info | Homo sapiens cDNA FLJ12900 fis, clone NT2RP2004321 | H008525_01 | AL049381 | 21851 | Perou’s – Intrinsic – Breast-Cancer-Genes, development, gene_regulation, transcription | 0.0950204 | 0.767 | |
| 1109 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003249_01 | Info | V-ets avian erythroblastosis virus E26 oncogene homolog 1 | H003249_01 | X14798 | 248109 | ETS1 | Keratinocyte Differentiation, METS affect on Macrophage Differentiation, tsonc | 0.1428371 | 0.878 |
| 1110 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H001295_01 | Info | Homeo box 11 (T-cell lymphoma 3-associated breakpoint) | H001295_01 | M62626 | 89583 | HOX11 | 0.147156 | 1.16 | |
| 1111 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003550_01 | Info | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | H003550_01 | S76638 | 73090 | NFKB2 | gene_regulation, immunology, transcription, tsonc | 0.1593331 | 1.165 |
| 1112 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003894_01 | Info | Checkpoint suppressor 1 | H003894_01 | U68723 | 211773 | CHES1 | cell_cycle, tsonc | 0.1638845 | 0.865 |
| 1113 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H015267_01 | Info | Myogenic factor 3 | H015267_01 | NM_002478 | 284203 | MYOD1 | Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Signal Dependent Regulation of Myogenesis by Corepressor MITR | 0.1671242 | 1.121 |
| 1114 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H004149_01 | Info | Core-binding factor, beta subunit | H004149_01 | L20298 | 179881 | CBFB | gene_regulation, immunology, transcription | 0.167453 | 1.179 |
| 1115 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002021_01 | Info | V-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein G | H002021_01 | AF059195 | 252229 | MAFG | Perou’s – Intrinsic – Breast-Cancer-Genes, Oxidative Stress Induced Gene Expression Via Nrf2, gene_regulation, transcription, tsonc | 0.1710773 | 1.129 |
| 1116 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H001297_01 | Info | Pre-B-cell leukemia transcription factor 1 | H001297_01 | M86546 | 155691 | PBX1 | Perou’s – Intrinsic – Breast-Cancer-Genes, development, gene_regulation, transcription | 0.1724831 | 1.132 |
| 1117 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H001986_01 | Info | Aryl hydrocarbon receptor | H001986_01 | NM_001621 | 170087 | AHR | Ahr Signal Transduction Pathway, gene_regulation, immunology, transcription | 0.1792938 | 1.117 |
| 1118 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 | 79070 | MYC | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 1119 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H001905_01 | Info | LPS-induced TNF-alpha factor | H001905_01 | NM_004862 | 76507 | PIG7 | 0.2026162 | 1.209 | |
| 1120 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H004003_01 | Info | FBJ murine osteosarcoma viral oncogene homolog B | H004003_01 | L49169 | 75678 | FOSB | FOSB gene expression and drug abuse, immunology, tsonc | 0.2326486 | 1.128 |
| 1121 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H009824_01 | Info | Apoptosis antagonizing transcription factor | H009824_01 | AJ249940 | 16178 | DED | 0.2327972 | 0.904 | |
| 1122 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003656_01 | Info | Ets variant gene 6 (TEL oncogene) | H003656_01 | U11732 | 169081 | ETV6 | immunology, tsonc | 0.3132143 | 0.905 |
| 1123 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H005858_01 | Info | GLI-Kruppel family member HKR3 | H005858_01 | NM_005341 | 2364 | HKR3 | tsonc | 0.3984807 | 1.092 |
| 1124 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003579_01 | Info | TGFB inducible early growth response | H003579_01 | S81439 | 82173 | TIEG | angiogenesis, cell_cycle, cell_signaling, immunology, misc | 0.431719 | 1.086 |
| 1125 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002261_01 | Info | Signal transducer and activator of transcription 5B | H002261_01 | U47686 | 244613 | STAT5B | 0.441402 | 1.071 | |
| 1126 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H000209_01 | Info | Ets variant gene 3 | H000209_01 | L16464 | 179214 | ETV3 | METS affect on Macrophage Differentiation, gene_regulation, transcription, tsonc | 0.4998239 | 1.065 |
| 1127 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H009068_01 | Info | Homo sapiens mRNA; cDNA DKFZp586N1323 (from clone DKFZp586N1323) | H009068_01 | AL080218 | 24064 | 0.509279 | 1.056 | ||
| 1128 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003019_01 | Info | Pre-B-cell leukemia transcription factor 2 | H003019_01 | X59842 | 93728 | PBX2 | development | 0.5530834 | 1.06 |
| 1129 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002518_01 | Info | Zinc finger protein, subfamily 1A, 1 (Ikaros) | H002518_01 | U40462 | 54452 | ZNFN1A1 | 0.5915437 | 0.94 | |
| 1130 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H009346_01 | Info | AML1 | H009346_01 | S76346 | 166060 | 0.6048212 | 1.054 | ||
| 1131 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H001305_01 | Info | Core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related | H001305_01 | D43638 | 31551 | CBFA2T1 | cell_cycle, immunology | 0.6362774 | 0.962 |
| 1132 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002195_01 | Info | Non-metastatic cells 1, protein (NM23A) expressed in | H002195_01 | X17620 | 118638 | NME1 | Endocytotic role of NDK, Phosphins and Dynamin, Granzyme A mediated Apoptosis Pathway, Purine metabolism, Pyrimidine metabolism, cell_cycle, cell_signaling, immunology, signal_transduction, tsonc | 0.6910793 | 0.967 |
| 1133 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H000354_01 | Info | Requiem, apoptosis response zinc finger gene | H000354_01 | AF001433 | 13495 | REQ | B Cell Survival Pathway | 0.7111938 | 1.04 |
| 1134 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H003056_01 | Info | FOS-like antigen 2 | H003056_01 | X16706 | 301612 | FOSL2 | Bone Remodelling, tsonc | 0.85065 | 1.018 |
| 1135 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002350_01 | Info | Peroxisome proliferative activated receptor, alpha | H002350_01 | L02932 | 998 | PPARA | Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Nuclear Receptors in Lipid Metabolism and Toxicity, Regulation of PGC-1a, �-arrestins in GPCR Desensitization, Toll-Like Receptor Pathway | 0.8655149 | 1.015 |
| 1136 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H002963_01 | Info | V-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide | H002963_01 | L19067 | 75569 | RELA | Acetylation and Deacetylation of RelA in The Nucleus, Erythropoietin mediated neuroprotection through NF-kB, Influence of Ras and Rho proteins on G1 to S Transition, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), NFkB activation by Nontypeable Hemophilus influenzae, NF-kB Signaling Pathway, immunology, tsonc | 0.9724165 | 1.003 |
| 1137 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H000210_01 | Info | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | H000210_01 | M57609 | 72916 | GLI3 | Sonic Hedgehog (Shh) Pathway, development, tsonc | 0.9937544 | 1.001 |
| 1138 | CR_TRANSCRIPTION_FACTORS_h | PNAS_2013 | H009950_01 | Info | Hypothetical protein PRO1635 | H009950_01 | AF138861 | 60548 | PRO1635 | cell_cycle, tsonc | 0.9954397 | 0.999 |
| 1139 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002040_01 | Info | Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) | H002040_01 | X00588 | 77432 | EGFR | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc | 0.0004362 | 0.669 |
| 1140 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 1141 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 1142 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002890_01 | Info | Ribosomal protein S6 kinase, 90kD, polypeptide 1 | H002890_01 | L07597 | 149957 | RPS6KA1 | Cell Cycle: G2/M Checkpoint, Erk1/Erk2 Mapk Signaling pathway, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, MAP Kinase Signaling Pathway, Melanocyte Development and Pigmentation Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Role of Erk5 in Neuronal Survival, Transcription factor CREB and its extracellular signals, Phosphatidylinositol signaling system | 0.0138896 | 1.42 |
| 1143 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H011228_01 | Info | G protein-coupled receptor kinase 7 | H011228_01 | AL137615 | 261828 | GPRK7 | Perou’s – Intrinsic – Breast-Cancer-Genes, Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, Phosphatidylinositol signaling system | 0.0572981 | 1.27 |
| 1144 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002473_01 | Info | Insulin-like growth factor 1 receptor | H002473_01 | NM_000875 | 239176 | IGF1R | Perou’s – Intrinsic – Breast-Cancer-Genes, Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK), Erk1/Erk2 Mapk Signaling pathway, IGF-1 Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Regulation of BAD phosphorylation, Skeletal muscle hypertrophy is regulated via AKT/mTOR pathway, Telomeres, Telomerase, Cellular Aging, and Immortality, The IGF-1 Receptor and Longevity, immunology | 0.079692 | 1.158 |
| 1145 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H014033_01 | Info | Dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | H014033_01 | NM_003863 | 108973 | DPM2 | 0.0983172 | 1.165 | |
| 1146 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H003178_01 | Info | Mitogen-activated protein kinase 3 | H003178_01 | X60188 | 861 | MAPK3 | Perou’s – Intrinsic – Breast-Cancer-Genes, Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, How Progesterone Initiates the Oocyte Maturation, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho … | 0.0986041 | 1.184 |
| 1147 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002775_01 | Info | Platelet-derived growth factor receptor, alpha polypeptide | H002775_01 | M21574 | 74615 | PDGFRA | Perou’s – Intrinsic – Breast-Cancer-Genes, CBL mediated ligand-induced downregulation of EGF receptors, Erk1/Erk2 Mapk Signaling pathway, PDGF Signaling Pathway, Phospholipids as signaling intermediaries, Rac 1 cell motility signaling pathway, Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration, immunology, signal_transduction | 0.1636921 | 1.107 |
| 1148 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002091_01 | Info | V-myc avian myelocytomatosis viral oncogene homolog | H002091_01 | K02276 | 79070 | MYC | Cadmium induces DNA synthesis and proliferation in macrophages, CTCF: First Multivalent Nuclear Factor, Erk1/Erk2 Mapk Signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, MAP Kinase Signaling Pathway, Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha), Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells, Overview of telomerase protein component gene hTert Transcriptional Regulation , p38 MAPK Signaling Pathway , Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Telomeres, Telomerase, Cellular Aging, and Immortality, Tumor Suppressor Arf Inhibits Ribosomal Biogenesis, WNT Signaling Pathway, gene_regulation, immunology, transcription, tsonc | 0.1797519 | 0.824 |
| 1149 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002405_01 | Info | Mitogen-activated protein kinase kinase 2 | H002405_01 | L11285 | 72241 | MAP2K2 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Bioactive Peptide Induced Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, fMLP induced chemokine gene expression in HMC-1 cells, Human Cytomegalovirus and Map Kinase Pathways, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Role of MAL in Rho-Mediated Activation of SRF, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling of Hepatocyte Growth Factor Receptor | 0.3118803 | 1.093 |
| 1150 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002724_01 | Info | Nerve growth factor receptor (TNFR superfamily, member 16) | H002724_01 | M14764 | 1827 | NGFR | Erk1/Erk2 Mapk Signaling pathway, Nerve growth factor pathway (NGF), Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway | 0.3282897 | 1.142 |
| 1151 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002722_01 | Info | Mitogen-activated protein kinase kinase 1 | H002722_01 | L11284 | 3446 | MAP2K1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Anthrax Toxin Mechanism of Action, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, Human Cytomegalovirus and Map Kinase Pathways, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links between Pyk2 and Map Kinas … | 0.7377933 | 0.973 |
| 1152 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H006522_01 | Info | Neuroendocrine secretory protein 55 | H006522_01 | AF105253 | 113368 | NESP55 | Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, Attenuation of GPCR Signaling, CCR3 signaling in Eosinophils, ChREBP regulation by carbohydrates and cAMP, Corticosteroids and cardioprotection, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, Erk1/Erk2 Mapk Signaling pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Phospholipase C-epsilon pathway, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Transcription factor CREB and its extracellular signals | 0.7456375 | 1.036 |
| 1153 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H002751_01 | Info | Nerve growth factor, beta polypeptide | H002751_01 | X52599 | 2561 | NGFB | BTG family proteins and cell cycle regulation, Erk1/Erk2 Mapk Signaling pathway, Nerve growth factor pathway (NGF), Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway, Trka Receptor Signaling Pathway, immunology, misc | 0.8279588 | 1.019 |
| 1154 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H003724_01 | Info | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | H003724_01 | NM_002211 | 202661 | ITGB1 | Adhesion and Diapedesis of Lymphocytes, Adhesion Molecules on Lymphocyte, Agrin in Postsynaptic Differentiation, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, B Cell Survival Pathway, Cells and Molecules involved in local acute inflammatory response, Eph Kinases and ephrins support platelet aggregation, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Integrin Signaling Pathway, mCalpain and friends in Cell motility, Monocyte and its Surface Molecules, PTEN dependent cell cycle arrest and apoptosis, Ras-Independent pathway in NK cell-mediated cytotoxicity, Signaling of Hepatocyte Growth Factor Receptor, Trefoil Factors Initiate Mucosal Healing, uCalpain and friends in Cell spread, cell_signaling, immunology, metastasis | 0.9378203 | 0.993 |
| 1155 | erkPathway_h | Cell growth is promoted by Ras activation of the anti-apoptotic p44/42 MAP kinase pathway. | H012856_01 | Info | MAP kinase-interacting serine/threonine kinase 1 | H012856_01 | AB000409 | 5591 | MKNK1 | Erk1/Erk2 Mapk Signaling pathway, MAP Kinase Signaling Pathway, mTOR Signaling Pathway, p38 MAPK Signaling Pathway , Regulation of eIF4e and p70 S6 Kinase, Phosphatidylinositol signaling system | 0.9455231 | 0.992 |
| 1156 | ST_G_alpha_i_Pathway__h | Signalling Transduction KE | H002040_01 | Info | Epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog) | H002040_01 | X00588 | 77432 | EGFR | Agrin in Postsynaptic Differentiation, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Keratinocyte Differentiation, Map Kinase Inactivation of SMRT Corepressor, mCalpain and friends in Cell motility, Neuroregulin receptor degradation protein-1 Controls ErbB3 receptor recycling, Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy, Role of ERBB2 in Signal Transduction and Oncology, Sprouty regulation of tyrosine kinase signals, Telomeres, Telomerase, Cellular Aging, and Immortality, The role of FYVE-finger proteins in vesicle transport, Trefoil Factors Initiate Mucosal Healing, angiogenesis, signal_transduction, tsonc | 0.0004362 | 0.669 |
| 1157 | ST_G_alpha_i_Pathway__h | Signalling Transduction KE | H002055_01 | Info | Growth factor receptor-bound protein 2 | H002055_01 | M96995 | 296381 | GRB2 | Activation of Src by Protein-tyrosine phosphatase alpha, Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Calcium Signaling by HBx of Hepatitis B virus, CBL mediated ligand-induced downregulation of EGF receptors, EGF Signaling Pathway, EPO Signaling Pathway, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 4 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Links between Pyk2 and Map Kinases, MAP Kinase Signaling Pathway, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Nerve growth factor pathway (NGF), p38 MAPK Signaling Pathway , PDGF Signaling Pathway, PTEN dependent cel … | 0.0022348 | 1.459 |
| 1158 | ST_G_alpha_i_Pathway__h | Signalling Transduction KE | H002893_01 | Info | V-raf-1 murine leukemia viral oncogene homolog 1 | H002893_01 | X03484 | 85181 | RAF1 | Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling, Aspirin Blocks Signaling Pathway Involved in Platelet Activation, BCR Signaling Pathway, Bioactive Peptide Induced Signaling Pathway, Cadmium induces DNA synthesis and proliferation in macrophages, CCR3 signaling in Eosinophils, Ceramide Signaling Pathway, CXCR4 Signaling Pathway, EGF Signaling Pathway, EPO Signaling Pathway, Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia, Erk1/Erk2 Mapk Signaling pathway, Fc Epsilon Receptor I Signaling in Mast Cells, fMLP induced chemokine gene expression in HMC-1 cells, Growth Hormone Signaling Pathway, IGF-1 Signaling Pathway, IL 2 signaling pathway, IL 3 signaling pathway, IL 6 signaling pathway, IL-2 Receptor Beta Chain in T cell Activation, Influence of Ras and Rho proteins on G1 to S Transition, Inhibition of Cellular Proliferation by Gleevec, Insulin Signaling Pathway, Integrin Signaling Pathway, Keratinocyte Differentiation, Links betw … | 0.0062484 | 1.596 |
| 1159 | ST_G_alpha_i_Pathway__h | Signalling Transduction KE | H001062_01 | Info | N-acylsphingosine amidohydrolase (acid ceramidase) | H001062_01 | U70063 | 75811 | ASAH | Perou’s – Intrinsic – Breast-Cancer-Genes, Activation of cAMP-dependent protein kinase, PKA, Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor, ChREBP regulation by carbohydrates and cAMP, Cystic fibrosis transmembrane conductance regulator (CFTR) and beta 2 adrenergic receptor (b2AR) pathway, How Progesterone Initiates the Oocyte Maturation, Ion Channels and Their Functional Role in Vascular Endothelium, Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation, Phospholipase C-epsilon pathway, Phospholipids as signaling intermediaries, Regulation of BAD phosphorylation, Regulation of Spermatogenesis by CREM, Role of �-arrestins in the activation and targeting of MAP kinases, Roles of �-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling, Signaling Pathway from G-Protein Families, �-arrestins in GPCR Desensitization, Thrombin signaling and protease-activated receptors, Transcription factor CREB and its … | 0.0187984 | 1.357 |
| 1160 | ST_G_alpha_i_Pathway__h | Signalling Transduction KE | H003628_01 | Info | Dystroglycan 1 (dystrophin-associated glycoprotein 1) | H003628_01 | L19711 | 76111 | DAG1 | Agrin in Postsynaptic Differentiation, immunology | 0.034627 | 0.774 |
| 1161 | ST_G_alpha_i_Pathway__h | Signalling Transduction KE | H016134_01 | Info | V-akt murine thymoma viral oncogene homolog 2 | H016134_01 | NM_001626 | 326445 | AKT2 | Phosphatidylinositol signaling system, cell_cycle, cell_signaling, signal_transduction, tsonc | 0.0530988 | 1.287 |