Dr. Zhang is Vice President and Chief Data Scientist for UTHealth. He is a Professor in the Department of Neurology, McGovern Medical School and Co-Director, Texas Institute for Restorative Neurotechnologies. Prior to joining UTHealth, he was Professor of Internal Medicine and Computer Science at the University of Kentucky, where he also served as the university’s inaugural Director for the Institute for Biomedical Informatics, and Associate Director for the Center for Clinical and Translational Science. His longest career stretch has been spent at Case Western Reserve University, where his role included Division Chief of Medical Informatics, Co-Director of Biomedical Research Information Management Core of the Case Western CTSA, and Associate Director for Case Comprehensive Cancer Center.
Dr. Zhang received his PhD from the University of Cambridge. His earlier research interests included theoretical computer science and semantics of programming languages. In the last decade, his research has revolved around Human-Data Interaction (HDITM), achieved through the development of innovative software and web-based applications spanning the biomedical data lifecycle. Software tools include query interface for clinical research, data management software for clinical trials and biomedical research, and tools for multi-site data integration. He led the development of data infrastructures and manages data resources, following the vision of NIH Data Commons, for the National Sleep Research Resource and for Center for Sudden Unexpected Death in Epilepsy Research, largest and most comprehensive, well-annotated clinical data sets in the two disease areas. He also has a track record of research in biomedical metadata including ontologies and terminology systems, to bring them to bear on HDI. Dr. Zhang effectively brings cutting-edge computer science and informatics methodology to addressing biomedical data/big data challenges through the translation of theory, algorithms, methods and best practices to functional and usable tools impacting the clinical research data lifecycle.


Philosophy, Cambridge University, England

Areas of Interest

Research Interests

Human Data Interaction (HDISM)
Big Data for Healthcare
Ontologies and Metadata
Software Tools and Data Integration for Clinical Applications
Large-scale Data Resource Development and Sharing


Visit the PubMed profile page

  1. Zhang GQ, Cui L, Mueller R, Tao S, Kim M, Rueschman M, Mariani S, Mobley D, Redline S. The National Sleep Research Resource: Towards a Sleep Data Commons. Journal of the American Medical Informatics Association. 2018 May 31. DOI: 10.1093/jamia/ocy064. PMID29860441
  2. Cui L, Zhu W, Tao S, Case JT, Bodenreider O, Zhang GQ. Mining Non-Lattice Subgraphs for Detecting Missing Hierarchical Relations and Concepts in SNOMED CT. Journal of the American Medical Informatics Association 2017 Feb 19. DOI:10.1093/jamia/ocw175. PMID: 28339775
  3. Zhang GQ, Cui L, Lhatoo S, Schuele S, Sahoo S. MEDCIS: Multi-Modality Epilepsy Data Capture and Integration System. AMIA Annual Symp Proc 2014;1248-57. PMC4420009
  4. Cui L, Bodenreider O, Shi J, Zhang GQ. Auditing SNOMED CT Hierarchical Relations Based on Lexical Features of Concepts in Non-lattice Subgraphs. Journal of Biomedical Informatics, 2018;78:177-184.  DOI: 10.1016/j.jbi.2017.12.010. PMID29274386
  5. Tao S, Cui L, Zhang GQ. Facilitating cohort discovery by enhancing ontology exploration, query management and query sharing for large clinical data repositories. AMIA Annual Symp Proc 2017, pp. 1668-1677. PMC5977665