Graduate School
Peking University Health Science Center (Beijing Medical University, Beijing, China, 1998
University of Texas M. D. Anderson Cancer Center, Houston, Texas, 1999 - 2004

Areas of Interest

Research Interests

Our research interests focus on the impact of probiotics in neonatal GI-related diseases and autoimmune disorders; the mechanism of probiotics in regulating immunity, modulating gut microbiota and microbial-associated metabolites; the effects of probiotics in gut-brain axis; and the effect of human breast milk factors on the function of probiotics.


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  1. Park ES, Freeborn J, Venna VR, Roos S, Rhoads JM, and Liu Y. Lactobacillus reuteri effects on maternal separation stress in newborn mice. Pediatric Research, 2021, Doi: 10.1038/s41390-021-01374-0.
  2. Liu Y, Tian X, He B, Hoang TK, Taylor CM, Blanchard E, Freeborn J, Park S, Luo M, Couturier J, Tran DQ, Roos S, Wu G, Rhoads JM. Lactobacillus reuteri DSM 17938 feeding of healthy newborn mice regulates immune responses while modulating gut microbiota and boosting beneficial metabolites. Am J Physiol Gastrointest Liver Physiol. 2019 Dec 1;317(6):G824-G838. PMID: 31482733; PMCID: PMC6962498.
  3. Hoang TK, Freeborn J, Wang T, Mai T, He B, Park S, Tran DQ, Roos S, Rhoads JM, Liu Y. Human Breast Milk Promotes the Immunomodulatory Function of Probiotic Lactobacillus reuteri DSM 17938 in the Neonatal Rat Intestine. J Probiotics Health. 2019;7(1). PMID: 31565666; PMCID: PMC6764460.
  4. Mai TT, Tran DQ, Roos S, Rhoads JM, Liu Y. Human Breast Milk Promotes the Secretion of Potentially Beneficial Metabolites by Probiotic Lactobacillus reuteri DSM 17938. Nutrients. 2019 Jul 9;11(7). PMID: 31323989; PMCID: PMC6683045.
  5. He B, Hoang TK, Tian X, Taylor CM, Blanchard E, Luo M, Bhattacharjee MB, Freeborn J, Park S, Couturier J, Lindsey JW, Tran DQ, Rhoads JM, Liu Y. Lactobacillus reuteri Reduces the Severity of Experimental Autoimmune Encephalomyelitis in Mice by Modulating Gut Microbiota. Front Immunol. 2019;10:385. PMID: 30899262; PMCID: PMC6416370.
  6. Hoang TK, He B, Wang T, Tran DQ, Rhoads JM, Liu Y. Protective effect of Lactobacillus reuteri DSM 17938 against experimental necrotizing enterocolitis is mediated by Toll-like receptor 2. Am J Physiol Gastrointest Liver Physiol. 2018 Aug 1;315(2):G231-G240. PMID: 29648878; PMCID: PMC6139641.
  7. He B, Hoang TK, Tran DQ, Rhoads JM, Liu Y. Adenosine A2A Receptor Deletion Blocks the Beneficial Effects of Lactobacillus reuteri in Regulatory T-Deficient Scurfy Mice. Front Immunol. 2017;8:1680. PMID: 29270168; PMCID: PMC5723640.
  8. He B, Hoang TK, Wang T, Ferris M, Taylor CM, Tian X, Luo M, Tran DQ, Zhou J, Tatevian N, Luo F, Molina JG, Blackburn MR, Gomez TH, Roos S, Rhoads JM, Liu Y. Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors. J Exp Med. 2017 Jan;214(1):107-123. PMID: 27994068; PMCID: PMC5206500.



  1. Rhoads JM, Collins J, Fatheree NY, Hashmi SS, Taylor CM, Luo M, Hoang TK, Gleason WA, Van Arsdall MR, Navarro F, Liu Y. Infant Colic Represents Gut Inflammation and Dysbiosis. J Pediatr. 2018 Dec;203:55-61. PMID: 30177353; PMCID: PMC6669027.
  2. Fatheree NY, Liu Y, Taylor CM, Hoang TK, Cai C, Rahbar MH, Hessabi M, Ferris M, McMurtry V, Wong C, Vu T, Dancsak T, Wang T, Gleason W, Bandla V, Navarro F, Tran DQ, Rhoads JM. Lactobacillus reuteri for Infants with Colic: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. J Pediatr. 2017 Dec;191:170-178. PMID: 28969890; PMCID: PMC6336100.



  1. Mai T, Fatheree NY, Gleason W, Liu Y, Rhoads JM. Infantile Colic: New Insights into an Old Problem. Gastroenterol Clin North Am. 2018 Dec;47(4):829-844. Review. PMID: 30337035; PMCID: PMC6659398.
  2. Liu Y, Alookaran JJ, Rhoads JM. Probiotics in Autoimmune and Inflammatory Disorders. Nutrients. 2018 Oct 18;10(10). Review. PMID: 30340338; PMCID: PMC6213508.
  3. Liu Y, Tran DQ, Rhoads JM. Probiotics in Disease Prevention and Treatment. J Clin Pharmacol. 2018 Oct;58 Suppl 10:S164-S179. PMID: 30248200; PMCID: PMC6656559.