Von Willebrand Disease

Von Willebrand Disease (VWD) is a genetic disorder caused by missing or defective clotting proteins called von Willebrand factor (VWF). VWD occurs equally in men and women and it is the most common bleeding disorder, affecting up to 1% of the US population.

Easy bruising, frequent and prolonged nosebleeds, and excessive bleeding during and after invasive procedures are common symptoms of VWD. Women with VWD often experience heavy menstrual bleeding and excessive bleeding after childbirth.

The best place for treatment for VWD is at a Hemophilia Treatment Center, like GSHTC, who provide comprehensive care from skilled hematologists and other professional staff members. The treatment for VWD depends on severity and may include a medication called DDAVP and Intravenous infusion of (VWF). Additionally the use of antfibrinolytic drugs like aminocaproic acid (Amicar) or tranexamic acid (Lysteda) taken by mouth are often recommended before dental procedures, to treat nose and mouth bleeds, and for heavy menstrual bleeding.