Selected Publications

Posey KL. Curcumin and Resveratrol: Nutraceuticals with so Much Potential for Pseudoachondroplasia and Other ER-Stress Conditions. Biomolecules. 2024 Jan 27;14(2):154. doi: 10.3390/biom14020154. PMID: 38397390; PMCID: PMC10886985.

Hecht JT, Veerisetty AC, Patra D, Hossain MG, Chiu F, Mobed C, Gannon FH, Posey KL. Early Resveratrol Treatment Mitigates Joint Degeneration and Dampens Pain in a Mouse Model of Pseudoachondroplasia (PSACH). Biomolecules. 2023 Oct 20;13(10):1553. doi: 10.3390/biom13101553. PMID: 37892235; PMCID: PMC10605626.

Hecht JT, Chiu F, Veerisetty A, Hossain M, Posey KL. Health consequences of mutant cartilage oligomeric matrix protein and its relationship to abnormal growth and joint degeneration. Matrix Biol. 2023 May;119:101-111. doi: 10.1016/j.matbio.2023.03.008. Epub 2023 Mar 30. PMID: 37001593.

Hecht JT, Veerisetty AC, Hossain MG, Chiu F, Posey KL. CurQ+, a Next-Generation Formulation of Curcumin, Ameliorates Growth Plate Chondrocyte Stress and Increases Limb Growth in a Mouse Model of Pseudoachondroplasia. Int J Mol Sci. 2023 Feb 14;24(4):3845. doi: 10.3390/ijms24043845. PMID: 36835255; PMCID: PMC9959842.

Hecht JT, Veerisetty AC, Hossain MG, Patra D, Chiu F, Coustry F, Posey KL. Joint Degeneration in a Mouse Model of Pseudoachondroplasia: ER Stress, Inflammation, and Block of Autophagy. Int J Mol Sci. 2021 Aug 26;22(17):9239. doi: 10.3390/ijms22179239. PMID: 34502142; PMCID: PMC8431545.

Hecht JT, Coustry F, Veerisetty AC, Hossain MG, Posey KL. Resveratrol Reduces COMPopathy in Mice Through Activation of Autophagy. JBMR Plus. 2021 Jan 22;5(3):e10456. doi: 10.1002/jbm4.10456. PMID: 33778324; PMCID: PMC7990140.

Schweiger S, Matthes F, Posey K, Kickstein E, Weber S, Hettich MM, Pfurtscheller S, Ehninger D, Schneider R, Krauß S. Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex. Sci Rep. 2017 Oct 23;7(1):13753. doi: 10.1038/s41598-017-12974-4. PMID: 29062069; PMCID: PMC5653760.