Selected Publications
Smad1 domains interacting with Hoxc-8 induce osteoblast differentiation
Yang, X, Ji, X, Shi, X, Cao, X. Smad1 domains interacting with Hoxc-8 induce osteoblast differentiation. J Biol Chem, 275(2), 1065-72, 2000
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome
Yang, X, Matsuda, K, Bialek, P, Jacquot, S, Masuoka, HC, Schinke, T, Li, L, Brancorsini, S, Sassone-Corsi, P, Townes, TM, Hanauer, A, Karsenty, G. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell, 117(3), 387-98, 2004
Vimentin inhibits ATF4-mediated osteocalcin transcription and osteoblast differentiation
Lian, N, Wang, W, Li, L, Elefteriou, F, Yang, X. Vimentin inhibits ATF4-mediated osteocalcin transcription and osteoblast differentiation. J Biol Chem, 284(44), 30518-25, 2009
Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh
Wang, W, Lian, N, Ma, Y, Li, L, Gallant, RC, Elefteriou, F, Yang, X. Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh. Development, 139(3), 601-11, 2012
FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation
Karolak, M.R., Yang, X., Elefteriou, F. FGFR1 signaling in hypertrophic chondrocytes is attenuated by the Ras-GAP neurofibromin during endochondral bone formation. Hum Mol Genet. 2015 24(9):2552-64. PMID: 25616962