Skip to main content
Selected Publications
Excess LIGHT contributes to placental impairment, increased secretion of vasoactive factors, hypertension, and proteinuria in preeclampsia Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage. Detrimental effects of adenosine signaling in sickle cell disease. A2B adenosine receptor-mediated induction of IL-6 promotes CKD. Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling. Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling. Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy. Autoantibody-mediated complement C3a receptor activation contributes to the pathogenesis of preeclampsia. Autoantibody-mediated angiotensin receptor activation contributes to preeclampsia through tumor necrosis factor-alpha signaling. Angiotensin receptor agonistic autoantibody-mediated tumor necrosis factor-alpha induction contributes to increased soluble endoglin production in preeclampsia. The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia. Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice.