Selected Publications
Year 2021:
- Wang R *, Lee J-H *, Xiong F, Kim J, Al Hasani L, Krakowiak J, Yuan X, et al. Eltzschig KH, Li W#. SARS-CoV-2 Restructures the Host Chromatin Architecture. bioRxiv. 2021 Jul 21. doi: 10.1101/2021.07.20.453146. PubMed PMID: 34312624; PubMed Central PMCID: PMC8312896. [Pre-print] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312896/
- Lee J-H *, Wang R *, Xiong F *, Krakowiak J, Liao Z, Nguyen P T, et al. Li W#. Enhancer RNA Methylation Orchestrates Transcriptional Condensate Formation and Gene Activation. Molecular Cell. (2021). 81(16):3368-3385.e9. doi: 10.1016/j.molcel.2021.07.024. PubMed PMID: 34375583. https://pubmed.ncbi.nlm.nih.gov/34375583/
- Oh S, Shao J *, Mitra J *, Xiong F, et al. Li W#, Rosenfeld MG#. “Enhancer Release and Retargeting” Activates Disease Susceptibility Genes. Nature. (2021). 595(7869):735-740. doi: 10.1038/s41586-021-03577-1. PubMed PMID: 34040254. https://pubmed.ncbi.nlm.nih.gov/34040254/
- Xiong F *, Wang R *, Lee J-H, Li S, Chen S-F, Liao Z, Nguyen P T, Zhu X, Krakowiak J, Tsai K-L, Liu Y, Li W#. RNA m6A Modification Orchestrates a LINE-1/Host Interaction That Facilitates Retrotransposition and Contributes to Long Gene Vulnerability. Cell Research. (2021) 8:861-885. doi: 10.1038/s41422-021-00515-8. PubMed PMID: 34108665. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324889/
- Hanmandlu A, Zhu L, Mertens TC, Collum S, Bi W, Xiong F, Wang R, Amirthalingam RT, Ren D, Han L, Jyothula SS, Li W, Zheng WJ, Karmouty-Quintana H. Transcriptomic and Epigenetic Profiling of Fibroblasts in Idiopathic Pulmonary Fibrosis (IPF). Am J Respir Cell Mol Biol. (2021). doi: 10.1165/rcmb.2020-0437OC. PubMed PMID: 34370624. https://pubmed.ncbi.nlm.nih.gov/34370624/
- Zhang Z, Hong W, Ruan H, Jing Y, Li S, Liu Y, Wang J, Li W, Diao L, Han L. HeRA: an atlas of enhancer RNAs across human tissues. doi: 10.1093/nar/gkaa940. PubMed PMID: 33119754; Nucleic Acids Res. (2021). 49(D1):D932-D938. doi: 10.1093/nar/gkaa940. PubMed PMID: 33119754. https://pubmed.ncbi.nlm.nih.gov/33119754/
Year 2020:
- Lin C, Li W. Noncoding RNAs as regulators of cancer. doi: 10.1080/15476286.2020.1813920. RNA Biol. (2020) [Editorial]. https://pubmed.ncbi.nlm.nih.gov/32892700/
- Yang M, Lee JH, Zhang Z, De La Rosa R, Bi M, Tan Y, Liao Y, Hong J, Du B, Wu Y, Scheirer J, Hong T, Li W, Fei T, Hsieh CL, Liu Z, Li W, Rosenfeld MG, Xu K. Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor. Cell Rep. (2020). doi: 10.1016/j.celrep.2020.107803. https://pubmed.ncbi.nlm.nih.gov/32579929/
- González-Rodríguez P, Cheray M, Füllgrabe J, Salli M, Engskog-Vlachos M, Keane L, Cunha V, Agata Lupa A, Li W, Ma Q, Dreij K, Rosenfeld MG, Joseph B. The DNA methyltransferase DNMT3A contributes to autophagy long-term memory. Autophagy. (2020). https://europepmc.org/article/pmc/pmc8143216
- Liao Z*, Lee J-H*, Krakowiak J, Wang R, Li W#. Enforced Activation of Enhancer RNAs In Situ through the dCas9 Synergistic Activation Mediator System. J Vis Exp. PMID: 32568241. (2020). https://pubmed.ncbi.nlm.nih.gov/32568241/
- Nguyen T; Kabotyanski E; Reineke L; Shao J; Xiong F; Lee J-H; Dubrulle J; Johnson H; Stossi F; Tsoi, P; Choi K-J; Ellis A; Zhao N; Cao J; Adewunmi O; Ferreon J; Ferreon A; Neilson J; Mancini M; Chen X; Kim J; Ma L; Li W; Rosen M. Jeff. The SINEB1 Element in the Long Non-coding RNA Malat1 is Necessary for TDP-43 Proteostasis. Nucleic Acids Research. (2020). https://pubmed.ncbi.nlm.nih.gov/31863590/
- Lee J-H*, Xiong F*, Li W#. Enhancer RNAs in Cancer: regulation, mechanisms and therapeutic potential. RNA Biology, (2020). [Review] https://pubmed.ncbi.nlm.nih.gov/31916476/
Years 2018 and 2019:
- Zhang Z *, Lee JH*, Ruan H*, Ye Y, Krakowiak J, et al., Li W #, and Han L#. Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer. #: Co-corresponding authors; *: co-first authors. Nature Communications. (2019). https://pubmed.ncbi.nlm.nih.gov/31594934/
- Ruan H; Xiang Y; Ko J; Li S; Jing Y; Zhu X; Ye Y; Zhang Z; Mills T; Feng J; Liu C; Diao L; Li W; Chen Z; He X; Mills G; Blackburn M; Han L. Comprehensive characterization of circular RNAs in ~1000 human cancer cell lines. Genome Medicine. (2019). https://pubmed.ncbi.nlm.nih.gov/31446897/
- Gu, Q. et al. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. http://science.sciencemag.org/content/363/6431/1085
- Cardamone, MD. et al. Mitochondrial retrograde signaling in mammals is mediated by the transcriptional cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation. Mol Cell. 69(5):757-772.e7.2018.
Years 2017 and 2016:
- Gao, X. et al. Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. PNAS. 114(38):10107-10112. 2017.
- Li W, Hu Y, Oh S, Ma Q, Merkurjev D, Song X, Zhou X, Liu Z, Tanasa B, He X, Chen AY, Ohgi K, Zhang J, Liu W, Rosenfeld MG. Condensin I and II Complexes License Full Estrogen Receptor a-Dependent Enhancer Activation. Mol Cell. 59:188-202. 2015.
- Li W, Notani D, Ma Q, Tanasa B, Nunez E, Chen AY, Merkurjev D, Zhang J, Ohgi K, Song X, Oh S, Kim HS, Glass CK, Rosenfeld MG. Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation. Nature. 498:516-20. 2013.
- Li W, Notani D, Rosenfeld MG. Enhancers as non-coding RNA transcription units: recent insights and future perspectives.. Nat Rev Genet. 17:207-23. 2016.