ChANGE-HD
Child to Adult Neurodevelopment in Gene Expanded Huntington’s Disease
Find this study on clinicaltrials.gov and the University of Iowa website.
| Sponsor | The University of Iowa / National Institutes of Health (NIH) |
| The Study | Child to Adult Neurodevelopment in Gene Expanded Huntington’s Disease (ChANGE-HD) is an observational multi-site brain imaging study that evaluates young people ages 6 to 30 who have a family history of HD (parent or grandparent) at risk of developing Huntington's disease. The study aims to understand how the gene responsible for HD affects brain development throughout the lifespan. |
| Main Goals | • Help explain how the gene responsible for HD affects brain development • Find a way to identify the best time for gene therapy during development • Understand structural and functional aspects of the brain |
| Who can participate? | • Ages 6 - 30 • Be at-risk for Huntington's disease (parent or grandparent with HD) • No history of brain tumor, brain surgery, major head trauma, or epilepsy |
| What is required of participants? | • For those age <18, participation by a parent or guardian • Screening process to ensure eligibility • Neurological exam • Surveys and questionnaires • Blood sample • MRI scan |
| Frequency of Participation | One in-person visit annually |
| Contact | Brittany Duncan at [email protected] or (713) 486-3134 |