Clinical Trials

CONTRAST-NP: Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Lebrikizumab/LY3650150 in Participants with Chronic Rhinosinusitis with Nasal Polyps on Background Intranasal Corticosteroids

• Ideal for adult participants ≥18 years and adolescent participants ≥12 to <18 years of age and weighing ≥40kg at Visit 1 with physician-diagnosed CRS with bilateral nasal polyps

---

DUET: Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

A randomized Phase 2, double-blind, placebo-controlled, parallel-group, 2-arm study to assess the efficacy, safety, and tolerability of subcutaneous lunsekimig in adult participants with chronic rhinosinusitis with nasal polyps (CRSwNP)

• Ideal for participants between the ages of 18 to 80 with ongoing symptoms of CRSwNP including: moderate to severe nasal congestion, blockage, or obstruction; partial or total loss of smell; anterior or posterior rhinorrhea