Clinical Trials

Allergic Fungal Rhinosinusitis

A randomized double-blind placebo-controlled parallel group study assessing the efficacy and safety of dupilumab in patients with Allergic Fungal Rhinosinusitis (AFRS)

• Patients with allergic fungal rhinosinusitis who have had surgery and now have worsening symptoms and recurrent nasal polyps

Chronic Rhinosinusitis with Nasal Polyps

A randomized, double-blind, head-to-head comparison of dupilumab versus omalizumab in severe Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) and comorbid asthma patients

• Ideal for patients with sinus polyps and asthma who have had surgery and now have worsening symptoms and recurrent nasal polyps

Chronic Rhinosinusitis

ENLIGHTEN 1: A Phase III, Randomized, Blinded, Controlled, Parallel-Group Trial to Evaluate the Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis (CRS) in Adults

• Ideal for patients with chronic rhinosinusitis who have not yet undergone sinus surgery with sinus symptoms wanting to trial a steroid releasing depot for treatment