Research

Here is an overview of the different lines of research happening at our center.

Bioengineering Approaches to Congenital Heart Disease (CHD)

• Modeling human heart development
• Modeling hypoplastic left heart syndrome (HLHS)
• Modeling Endocardial Fibro-elastosis
• Modeling pulmonary artery atresia
• Modeling pulmonary vein stenosis
• Modeling Fontan-associated liver disease (FALD)

Regenerative Medicine Approaches to Congenital Heart Disease (CHD)

• Bioengineered patch devices for CHD reconstruction
• 3D bioprinted cardiac patch to address CHD-associated ischemic injuries

Bioengineering Approaches to Adult Cardiovascular Disease (CVD)

• Cardiac patch devices to treat myocardial infarction
• In vitro modeling of atherosclerosis defects
• In vitro human-based models of ischemic heart injuries
• Modeling coronary aneurysms

Non-Cardiac Research Projects

• Liver disease-on-a-chip platforms
• In vitro modeling of pediatric solid tumors
• In vitro modeling of human brain development and diseases
• Dental tissue engineering – 3D bioprinting
• Orthopedic tissue engineering – 3D bioprinting