About the Center

The UTHealth Houston Center for Interventional Psychiatry is a specialized clinical, academic, and educational center dedicated to the care of individuals with severe, complex, and treatment-resistant psychiatric illness. We bring together expertise in psychiatry, neuromodulation, and multidisciplinary care to deliver advanced, evidence-based treatments across the full continuum of care.

The Center was established to address a critical gap in mental health care: patients whose illness does not respond to standard treatments and who require more precise, timely, and intensive interventions. Our team focuses on conditions marked by high symptom burden, functional impairment, and elevated risk, where conventional approaches alone are often insufficient.

We are organized around a matched-care model, meaning that each patient is carefully evaluated and directed to the most appropriate level of care and treatment modality from the outset. Care is delivered across outpatient, intensive outpatient, partial hospitalization, and inpatient settings, allowing patients to move seamlessly between levels as clinical needs evolve.

The Center’s flagship clinical service is the Treatment-Resistant Depression (TRD) Program, which integrates medication optimization, psychotherapy, and interventional psychiatry—including electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine and esketamine, and other neuromodulation approaches—within a coordinated and outcomes-focused framework.

In addition to clinical care, the Center plays a central role in education, research, and national and international collaboration, training clinicians in interventional psychiatry and advancing treatment for mood and other severe psychiatric disorders. Through this integrated mission, we aim to improve patient outcomes while advancing the field of psychiatry.