Bipolar Disorder in Adults

Stem Cell Clinical Trial for Treatment-Resistant Bipolar Depression

The purpose of this placebo-controlled study is to test the use of one infusion of stem cells in addition to a mood stabilizing medication as a treatment for bipolar disorder.


Transcranial Direct Current Stimulation (tDCS) for Bipolar Disorder

The purpose of this study is to investigate whether non-invasive transcranial direct current stimulation (tDCS) therapy will reduce symptoms of depression and anhedonia (lack of pleasure) in people with Bipolar Disorder.


BD2 Integrated Network & Longitudinal Cohort Study

We invite you to participate in an observational study aimed at filling the gaps in our overall understanding of Bipolar Disorder. This is the largest and most comprehensive longitudinal study of its kind, conducted in collaboration with five prestigious institutions: Mayo Clinic, Johns Hopkins, Harvard/McLean, University of Michigan, and UCLA.


Reasons for or Experiences with the Use of Psychedelics in Individuals with Bipolar Disorder

The purpose of this study is to gather information from individuals with Bipolar Disorder in order to assess (1) motivations for using or considering using classic psychedelics; (2) experiences and/or expectations of experiences of using; (3) whether certain factors related to their personality and mental health may affect these motivations and/or experiences; and (4) whether use of classic psychedelics can impact the symptom presentation of their bipolar disorder.


Fatty Acid Inhibitor Treatment in Bipolar Depression

The purpose of this study is to investigate a new potential antidepressant called palmitoylethanolamide (PEA) alongside a mood stabilizer in patients with bipolar disorder. Eligible participants will receive a clinical evaluation, daily treatment with refills free of charge, and regular follow ups with the study team.


VNS Therapy® System Versus No Stimulation for Treatment-Resistant Depression

This study aims to investigate vagus nerve stimulation (VNS) as an antidepressant treatment for people with bipolar disorder, whose depressive symptoms did not respond to medications.


Exploring the emotional regulation and executive functioning in individuals with bipolar disorder and autistic traits

The purpose of the present study is to understand the relationship between emotional regulation and executive functioning in adults with bipolar disorder (BD) and autistic traits.


Magnetic Seizure Therapy in Bipolar Depression and Treatment Resistant Depression

The purpose of this study is to obtain a preliminary comparison of the feasibility, safety, and efficacy of Magnetic Seizure Therapy (MST) and Electroconvulsive Therapy (ECT).


Use of the Videra Health Phone App for Patients with Bipolar Disorder

The Videra Health application software (app) is a new technology used by doctors to help provide better care for patients by collecting information about their symptoms in between office visits. During this one-year-long study, eligible participants will use a free-of-charge app downloaded on their phone or computer to track their mood by filling out short structured surveys. This study includes periodic assessments through the app and seven remote check-ins with the study team.