Rapid Reversal of Suicidal Depression: Comparative Effectiveness of Electroconvulsive Therapy vs. Ketamine

Principal Investigator: Joao L. De Quevedo, MD, PhD

Study Contact

Name: BSC Research Team

Email Address: [email protected]

Phone Number:

This study is currently looking for people who:

• Are 18 – 90 years of age.
• Are considered by a clinician as appropriate for referral to treatment services for rapid reversal of acute suicidal depression.
• Meet DSM-5 criteria for Major Depressive Episode (MDE).
• Have acute suicidal ideation or behavior (thinking or behavior suggesting harming or hurting oneself with knowledge that death may result) or attempt.
• Continue to express suicidal ideation since referral.

Study Description:

This study will compare the effectiveness of ketamine compared to electroconvulsive therapy for the treatment of acute suicidal depression. An additional aim is to assess the effects of acute treatment with ketamine or electroconvulsive therapy on the effectiveness of a therapy method called Collaborative Assessment and Management of Suicide after acute treatment and during a 6-month follow-up.

All participants will be compensated for their time.