Rapid Reversal of Suicidal Depression: Comparative Effectiveness of Electroconvulsive Therapy vs. Ketamine

Principal Investigator

Joao L. De Quevedo, MD, PhD

Overview:

This study will compare the effectiveness of ketamine compared to electroconvulsive therapy for the treatment of acute suicidal depression. An additional aim is to assess the effects of acute treatment with ketamine or electroconvulsive therapy on the effectiveness of a therapy method called Collaborative Assessment and Management of Suicide after acute treatment and during a 6-month follow-up.

Inclusion Criteria:

• Adults 18 – 90 years of age.
• Meet DSM-5 criteria for Major Depressive Episode (MDE)
• Considered by a clinician as appropriate for referral to treatment services for rapid reversal of acute suicidal depression.
• Have acute suicidal ideation or behavior (thinking or behavior suggesting harming or hurting oneself with the knowledge that death may result) or attempt.
• Continue to express suicidal ideation since referral.

What you may be asked to do:

• Completing surveys.
• Office visits.

What You May Get:

You may be compensated for your time.

Location:

Interventional Psychiatry Clinic

7000 Fannin Street, Suite 1620

Houston, TX, 77030

Contact:

Email: [email protected]

Phone: (713) 486-2567

Take the study survey here 

ClinicalTrials.gov ID: NCT06034821 (https://clinicaltrials.gov/study/NCT06034821)