The Genomics of Electroconvulsive Therapy (ECT)

Principal Investigator

Joao L. De Quevedo, MD, PhD

Overview:

This study is being carried out to investigate the genetic factors that contribute to mood disorders, specifically major depressive disorder (MDD) and bipolar disorder. This study is also being conducted to investigate how genetic factors can contribute to patient response to Electroconvulsive Therapy (ECT). This study aims to learn whether we can, very early on in treatment or even at first presentation, identify people who will likely respond well to ECT versus people who will likely respond poorly or have adverse effects from ECT.

This is a research study, and all participants are volunteers.

Inclusion Criteria:

• 18 years or older

• Primary lifetime diagnosis of MDD or BPD.
• Currently receiving ECT.
• Has received ECT in the past.
• Is/was a candidate for ECT but declined or opted for another non-first line treatment, such as repetitive transcranial magnetic stimulation or IV/IN ketamine.
• Is/was admitted and treated in the hospital for a severe major depressive episode.
• Additional criteria will apply.

What you may be asked to do:

• You will be asked to provide a blood or a saliva sample at one of the study sites, likely during a regular clinical visit.

Location:

Interventional Psychiatry Clinic

7000 Fannin Street, Suite 1620

Houston, TX, 77030

Contact:

Email: [email protected]

Phone: (713) 486-2567

Take the study survey here