Transcranial Electric Stimulation in Anhedonia Treatment of Bipolar Depression

Principal Investigator: Jair C. Soares, MD, PhD

Study Contact

Name: Dana Razouq

Email Address: UTMoodDisorders@uth.tmc.edu

Phone number: 713-486-2523

This study is currently looking for people who:

• Are 18 to 50 years old
• Current bipolar depression
• No substance abuse or dependence
• No diagnosed neurological conditions or severe/uncontrolled medical problems

Study Description:

The purpose of this study is to investigate whether transcranial direct current stimulation (tDCS) therapy will reduce symptoms of depression and anhedonia (lack of pleasure) in people with bipolar disorder. tDCS is an investigational tool for non-invasive brain stimulation. It is a wearable device, similar to a helmet, which delivers low-level electrical signals to the outside of the scalp. In addition to 14 sessions of tDCS therapy and two magnetic resonance imaging (MRI) scans of your brain, this 6-week long study includes clinical and laboratory evaluations, questions about mood, other medical conditions, drug use and you will be asked to provide a blood sample.

All participants will be compensated for their time.