VNS RECOVER Study

Principal Investigator

Joao L. De Quevedo, MD, PhD

Overview:

The UTHealth Houston Center for Interventional Psychiatry at the Faillace Department of Psychiatry and Behavioral Sciences is collaborating with LivaNova, a global medical technology company, to start a new clinical trial – the “RECOVER study” – to help treat depression.

The primary objective of this study is to comprehensively evaluate the effectiveness of active VNS Therapy compared to a no-stimulation control group in achieving a significant reduction in baseline depressive symptom severity. This evaluation will be conducted using various validated depression assessment tools to ensure a robust measurement of outcomes. The assessments will be carried out at the 12-month follow-up period after randomization, allowing for a thorough analysis of the long-term impacts of VNS Therapy on depression symptoms.

Inclusion Criteria:

• 18 years or older.
• Currently depressed.
• Have depression, or bipolar depression, that has lasted for more than two years or recurred several times.
• Have tried at least four types of antidepressant treatments and have not found them helpful.
• Additional criteria will apply.

What you may be asked to do:

• Office visits.
• Completing surveys.

What You May Get:

All participants in the study will receive VNS therapy and all study-related care at no cost to them.

You may be compensated on a per-visit basis.

Location:

Interventional Psychiatry Clinic

7000 Fannin Street, Suite 1620

Houston, TX, 77030

Contact:

Email: [email protected]

Phone: (713) 486-2567

Take the study survey here

ClinicalTrials.gov ID: NCT03887715 (https://clinicaltrials.gov/study/NCT03887715)